## Sat Nov 16 14:16:29 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin8/HKD_2_bin.42.fa -m mmseqs --itype genome -o HKD_2_bin.42 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HKD_2_bin.42 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD2_k127_10048457_1	1449044.JMLE01000048_gene2759	1.905e-75	257.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,1W93C@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
HKD2_k127_10048457_0	1449044.JMLE01000048_gene2760	2.187e-94	323.0	COG0739@1|root,COG0739@2|Bacteria,2IT6R@201174|Actinobacteria,1W9X7@1268|Micrococcaceae	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD2_k127_10049431_3	930171.Asphe3_22800	3.039e-54	190.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,1W7XQ@1268|Micrococcaceae	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD2_k127_10049431_1	290399.Arth_2404	3.448e-135	434.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,1W7RW@1268|Micrococcaceae	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD2_k127_10049431_0	290399.Arth_2403	1.071e-264	820.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,1W7WZ@1268|Micrococcaceae	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD2_k127_10049431_2	1150398.JIBJ01000004_gene2687	1.005e-108	356.0	COG3917@1|root,COG3917@2|Bacteria,2I2EX@201174|Actinobacteria,1W8ZH@1268|Micrococcaceae	201174|Actinobacteria	Q	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
HKD2_k127_10053548_1	452863.Achl_1635	9.056e-83	276.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,1W8KX@1268|Micrococcaceae	201174|Actinobacteria	E	Amino acid permease	ydaO	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD2_k127_10053548_0	1150398.JIBJ01000003_gene1894	3.297e-129	414.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,1W82W@1268|Micrococcaceae	201174|Actinobacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD2_k127_10053548_2	1150398.JIBJ01000003_gene1895	5.511e-74	249.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,1W7MF@1268|Micrococcaceae	201174|Actinobacteria	P	Putative NAD(P)-binding	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD2_k127_10131825_4	1449069.JMLO01000006_gene1050	5.337e-22	96.0	COG0492@1|root,COG2227@1|root,COG0492@2|Bacteria,COG2227@2|Bacteria,2GIXN@201174|Actinobacteria,4FYCP@85025|Nocardiaceae	201174|Actinobacteria	O	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,Pyr_redox_2
HKD2_k127_10131825_0	290399.Arth_1985	5.369e-159	516.0	COG2200@1|root,COG2200@2|Bacteria,2IIRA@201174|Actinobacteria	201174|Actinobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PAS,PAS_3,Response_reg
HKD2_k127_10131825_1	1151119.KB895489_gene514	7.474e-68	241.0	COG1846@1|root,COG1846@2|Bacteria,2IKTI@201174|Actinobacteria,1W9DT@1268|Micrococcaceae	201174|Actinobacteria	K	Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_10131825_2	1150398.JIBJ01000002_gene1123	1.925e-32	126.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,1W859@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA8	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD2_k127_10136957_2	269798.CHU_1108	4.253e-06	54.0	COG0457@1|root,COG0457@2|Bacteria	269798.CHU_1108|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_10136957_1	379731.PST_0581	5.001e-88	300.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1Z0CJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	ISPsy14, transposition helper protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
HKD2_k127_10136957_0	768671.ThimaDRAFT_1929	1.941e-189	605.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1WYPQ@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
HKD2_k127_10152773_1	290399.Arth_1594	9.019e-112	369.0	COG0834@1|root,COG0834@2|Bacteria,2I3WP@201174|Actinobacteria	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
HKD2_k127_10152773_0	1150398.JIBJ01000014_gene2463	8.909e-172	541.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,1W7KP@1268|Micrococcaceae	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
HKD2_k127_103155_2	1150398.JIBJ01000013_gene2563	1.336e-185	589.0	COG1028@1|root,COG1028@2|Bacteria,2GKUH@201174|Actinobacteria,1W878@1268|Micrococcaceae	201174|Actinobacteria	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HKD2_k127_103155_0	290399.Arth_2140	5.107e-273	844.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,1W8FD@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD2_k127_103155_1	290399.Arth_2141	4.135e-245	759.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,1W7XG@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	glgA	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD2_k127_103155_3	290399.Arth_2142	1.616e-69	237.0	COG1960@1|root,COG1960@2|Bacteria,2GJ4X@201174|Actinobacteria,1W7FR@1268|Micrococcaceae	201174|Actinobacteria	I	Acyl-CoA oxidase	acx	-	1.3.3.6	ko:K00232	ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146	M00087,M00113	R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_1037654_2	1151119.KB895500_gene2838	4.807e-25	104.0	COG1073@1|root,COG1073@2|Bacteria,2IQZN@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
HKD2_k127_1037654_1	1150398.JIBJ01000002_gene1266	6.469e-124	403.0	COG1435@1|root,COG1435@2|Bacteria,2GP1W@201174|Actinobacteria,1W8G5@1268|Micrococcaceae	201174|Actinobacteria	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
HKD2_k127_1037654_0	1150398.JIBJ01000002_gene1264	4.112e-315	970.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,1W7PA@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD2_k127_1037654_3	290399.Arth_0166	4.581e-15	81.0	2CC6F@1|root,33HJ8@2|Bacteria,2GX96@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1037654_4	290399.Arth_0167	9.711e-12	65.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,1W9R3@1268|Micrococcaceae	201174|Actinobacteria	S	Lsr2	lsr	-	-	-	-	-	-	-	-	-	-	-	Lsr2
HKD2_k127_104809_3	1158050.KB895452_gene165	1.503e-45	166.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
HKD2_k127_104809_0	1150398.JIBJ01000015_gene2024	0.0	1005.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,1W7WD@1268|Micrococcaceae	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HKD2_k127_104809_1	290399.Arth_2624	8.204e-275	850.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,1W7KA@1268|Micrococcaceae	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD2_k127_104809_2	290399.Arth_2623	8.051e-126	404.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,1W7RG@1268|Micrococcaceae	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
HKD2_k127_1059199_1	290399.Arth_1163	7.185e-32	124.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,1W7XV@1268|Micrococcaceae	201174|Actinobacteria	G	PFAM Aldose 1-epimerase	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HKD2_k127_1059199_0	1449044.JMLE01000007_gene1213	4.771e-186	595.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,1W8PC@1268|Micrococcaceae	201174|Actinobacteria	S	AI-2E family transporter	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
HKD2_k127_1080980_1	1449044.JMLE01000020_gene1859	7.755e-89	295.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,1W8P6@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qorA	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_1080980_0	290399.Arth_1490	0.0	1489.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,1W7VN@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HKD2_k127_1080980_2	1449044.JMLE01000020_gene1864	7.659e-40	147.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,1W80T@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HKD2_k127_1127158_1	1445613.JALM01000137_gene3678	6.523e-10	62.0	COG1397@1|root,COG1397@2|Bacteria,2GNSG@201174|Actinobacteria,4E3K0@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HKD2_k127_1127158_0	106370.Francci3_1108	1.461e-105	356.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_1171246_1	1150398.JIBJ01000013_gene2559	6.318e-107	351.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria,1W9FD@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_1171246_0	290399.Arth_2144	2.311e-255	794.0	COG0183@1|root,COG0183@2|Bacteria,2GJI8@201174|Actinobacteria,1W7KQ@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_1171246_2	290399.Arth_2145	1.497e-15	77.0	COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria,1W8K3@1268|Micrococcaceae	201174|Actinobacteria	IQ	KR domain	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD2_k127_119117_2	1150398.JIBJ01000014_gene2418	8.704e-101	330.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,1W83Q@1268|Micrococcaceae	201174|Actinobacteria	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD2_k127_119117_1	1150398.JIBJ01000014_gene2417	1.673e-122	397.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,1W9C1@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
HKD2_k127_119117_0	1150398.JIBJ01000014_gene2416	4.622e-131	423.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,1W9C1@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
HKD2_k127_119117_3	1158050.KB895467_gene3311	0.0006871	51.0	2EN8E@1|root,33FW7@2|Bacteria,2GVUH@201174|Actinobacteria,1WAA0@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_12254_0	1150398.JIBJ01000002_gene1224	4.524e-264	819.0	COG2610@1|root,COG2610@2|Bacteria,2GITQ@201174|Actinobacteria,1WAK9@1268|Micrococcaceae	201174|Actinobacteria	EG	GntP family permease	ygbN	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
HKD2_k127_12254_1	1150398.JIBJ01000002_gene1223	4.639e-105	352.0	COG0191@1|root,COG0191@2|Bacteria,2H640@201174|Actinobacteria,1WAJH@1268|Micrococcaceae	201174|Actinobacteria	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HKD2_k127_1295289_6	1158050.KB895464_gene3587	1.954e-39	146.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,1W7H8@1268|Micrococcaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HKD2_k127_1295289_0	1449044.JMLE01000006_gene1116	1.936e-167	531.0	COG0306@1|root,COG0306@2|Bacteria,2IK67@201174|Actinobacteria,1W8DN@1268|Micrococcaceae	201174|Actinobacteria	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD2_k127_1295289_2	290399.Arth_0207	2.444e-112	364.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,1W914@1268|Micrococcaceae	201174|Actinobacteria	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HKD2_k127_1295289_1	1150398.JIBJ01000002_gene1238	1.782e-125	403.0	28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,1W8ZY@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1295289_7	1077972.ARGLB_027_01770	1.398e-11	65.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,1W7MZ@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HKD2_k127_1295289_4	1150398.JIBJ01000002_gene1237	6.855e-72	245.0	COG1846@1|root,COG1846@2|Bacteria,2IKTI@201174|Actinobacteria,1W9DT@1268|Micrococcaceae	201174|Actinobacteria	K	Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_1295289_3	290399.Arth_4035	2.109e-83	287.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria,1W9CQ@1268|Micrococcaceae	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HKD2_k127_1295289_5	1906.SFRA_18015	3.288e-69	239.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
HKD2_k127_131454_0	1449353.JQMQ01000005_gene5431	5.786e-153	488.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,2NH8V@228398|Streptacidiphilus	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_131454_1	1150398.JIBJ01000002_gene1195	1.242e-94	313.0	COG1540@1|root,COG1540@2|Bacteria,2H5Y7@201174|Actinobacteria,1W97I@1268|Micrococcaceae	201174|Actinobacteria	S	5-oxoprolinase (ATP-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1326293_6	1150398.JIBJ01000008_gene822	1.822e-131	421.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,1W8QF@1268|Micrococcaceae	201174|Actinobacteria	C	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
HKD2_k127_1326293_0	1150398.JIBJ01000008_gene821	0.0	1270.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,1WA7A@1268|Micrococcaceae	201174|Actinobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
HKD2_k127_1326293_5	1150398.JIBJ01000008_gene820	7.09e-145	464.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,1W9AZ@1268|Micrococcaceae	201174|Actinobacteria	K	DeoR C terminal sensor domain	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HKD2_k127_1326293_1	1150398.JIBJ01000008_gene819	0.0	1247.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
HKD2_k127_1326293_4	1150398.JIBJ01000008_gene818	8.542e-163	524.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,1W9JF@1268|Micrococcaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HKD2_k127_1326293_3	1150398.JIBJ01000008_gene817	2.746e-173	546.0	COG1175@1|root,COG1175@2|Bacteria,2GKC2@201174|Actinobacteria,1WAN6@1268|Micrococcaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
HKD2_k127_1326293_2	1150398.JIBJ01000008_gene816	6.058e-265	818.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,1W9G1@1268|Micrococcaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HKD2_k127_1326293_8	1240349.ANGC01000001_gene2594	1.593e-99	334.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4FV6H@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
HKD2_k127_1326293_9	1150398.JIBJ01000021_gene3740	3.772e-98	334.0	COG1252@1|root,COG1252@2|Bacteria,2GKC0@201174|Actinobacteria	201174|Actinobacteria	C	pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD2_k127_1326293_7	1150398.JIBJ01000008_gene806	1.122e-124	407.0	COG2356@1|root,COG3064@1|root,COG2356@2|Bacteria,COG3064@2|Bacteria,2GJ38@201174|Actinobacteria,1W840@1268|Micrococcaceae	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,Excalibur
HKD2_k127_1330598_1	1150398.JIBJ01000007_gene258	1.268e-94	316.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,1W7XS@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HKD2_k127_1330598_0	1150398.JIBJ01000007_gene257	4.224e-209	656.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,1W8KD@1268|Micrococcaceae	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HKD2_k127_1337337_0	1150398.JIBJ01000008_gene759	1.252e-114	373.0	COG1649@1|root,COG1649@2|Bacteria,2GXT3@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1346223_1	290399.Arth_4082	2.193e-135	434.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1W8PN@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_1346223_0	1150398.JIBJ01000007_gene175	3.195e-141	453.0	COG1414@1|root,COG1414@2|Bacteria,2GNAS@201174|Actinobacteria,1W95D@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_1350538_3	1449044.JMLE01000001_gene3764	2.762e-76	257.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,1W87F@1268|Micrococcaceae	201174|Actinobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
HKD2_k127_1350538_4	452863.Achl_2150	6.963e-72	244.0	2EHND@1|root,33BE5@2|Bacteria,2IKQN@201174|Actinobacteria,1W9N8@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4233)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4233
HKD2_k127_1350538_2	290340.AAur_2371	8.44e-83	279.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,1W92C@1268|Micrococcaceae	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
HKD2_k127_1350538_1	1150398.JIBJ01000004_gene2702	1.02e-118	384.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,1W8VR@1268|Micrococcaceae	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
HKD2_k127_1350538_0	1150398.JIBJ01000004_gene2703	4.215e-295	923.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,1W83P@1268|Micrococcaceae	201174|Actinobacteria	J	ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
HKD2_k127_1357145_4	1449044.JMLE01000019_gene1758	1.79e-117	378.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HKD2_k127_1357145_1	1151119.KB895493_gene1492	1.852e-286	883.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,1W7K3@1268|Micrococcaceae	201174|Actinobacteria	J	Probable RNA and SrmB- binding site of polymerase A	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
HKD2_k127_1357145_5	290340.AAur_4195	2.104e-108	361.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,1W91C@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX domain	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_1357145_0	1150398.JIBJ01000007_gene229	0.0	1041.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,1W83Z@1268|Micrococcaceae	201174|Actinobacteria	S	Integral membrane protein MviN	mviN	GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HKD2_k127_1357145_2	1150398.JIBJ01000007_gene230	2.303e-200	636.0	COG0515@1|root,COG0515@2|Bacteria,2IHZJ@201174|Actinobacteria,1W838@1268|Micrococcaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1357145_3	1150398.JIBJ01000007_gene231	6.196e-199	623.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,1W849@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD2_k127_1357145_6	1150398.JIBJ01000007_gene232	1.512e-63	218.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,1W9S8@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD2_k127_1360845_1	1150398.JIBJ01000002_gene1146	1.737e-45	166.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,1W9YD@1268|Micrococcaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
HKD2_k127_1360845_0	1150398.JIBJ01000002_gene1145	2.218e-162	516.0	COG0697@1|root,COG0697@2|Bacteria,2GNSA@201174|Actinobacteria,1WBFM@1268|Micrococcaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_1360845_2	1150398.JIBJ01000002_gene1144	5.226e-10	60.0	COG0583@1|root,COG0583@2|Bacteria,2GJEC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	iciA	GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K05596	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_1,LysR_substrate
HKD2_k127_1366204_2	1150398.JIBJ01000010_gene600	3.038e-147	469.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,1W7I3@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter	fhuC	-	-	ko:K02074	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
HKD2_k127_1366204_3	1150398.JIBJ01000010_gene599	1.775e-117	385.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,1W7HJ@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	psaA	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
HKD2_k127_1366204_1	1150398.JIBJ01000010_gene598	1.234e-193	608.0	COG1253@1|root,COG1253@2|Bacteria,2GJ8X@201174|Actinobacteria,1W7K9@1268|Micrococcaceae	201174|Actinobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
HKD2_k127_1366204_0	1150398.JIBJ01000010_gene597	4.604e-243	755.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,1W81T@1268|Micrococcaceae	201174|Actinobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD2_k127_1368226_0	1150398.JIBJ01000014_gene2412	0.0	1232.0	COG1038@1|root,COG1038@2|Bacteria,2H238@201174|Actinobacteria,1W85S@1268|Micrococcaceae	201174|Actinobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
HKD2_k127_1368226_1	290399.Arth_1545	7.378e-97	321.0	COG1192@1|root,COG1192@2|Bacteria,2H4UC@201174|Actinobacteria,1W8MJ@1268|Micrococcaceae	201174|Actinobacteria	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HKD2_k127_1382894_0	1150398.JIBJ01000015_gene1947	4.9e-144	461.0	COG1305@1|root,COG1305@2|Bacteria,2GMD7@201174|Actinobacteria,1W9BX@1268|Micrococcaceae	201174|Actinobacteria	E	Transglutaminase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HKD2_k127_1382894_1	1150398.JIBJ01000015_gene1946	4.287e-70	243.0	COG1846@1|root,COG1846@2|Bacteria,2IMUX@201174|Actinobacteria,1W9WZ@1268|Micrococcaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_1382894_2	1077972.ARGLB_096_00130	1.435e-42	156.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,1W7UR@1268|Micrococcaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_1384611_7	1150398.JIBJ01000007_gene99	1.186e-23	101.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,1WARJ@1268|Micrococcaceae	201174|Actinobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
HKD2_k127_1384611_1	1150398.JIBJ01000007_gene100	9.961e-281	868.0	COG1027@1|root,COG1027@2|Bacteria,2I2HG@201174|Actinobacteria,1WAJE@1268|Micrococcaceae	201174|Actinobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD2_k127_1384611_0	290399.Arth_3977	5.535e-295	910.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,1W8VG@1268|Micrococcaceae	201174|Actinobacteria	E	PFAM Amino acid	ansP	-	-	ko:K11738	-	-	-	-	ko00000,ko02000	2.A.3.1.8	-	-	AA_permease
HKD2_k127_1384611_2	1449044.JMLE01000014_gene2407	9.039e-258	798.0	COG0454@1|root,COG0464@1|root,COG0456@2|Bacteria,COG0464@2|Bacteria,2GJ07@201174|Actinobacteria,1WAZR@1268|Micrococcaceae	201174|Actinobacteria	KO	Belongs to the AAA ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Acetyltransf_1
HKD2_k127_1384611_4	1150398.JIBJ01000007_gene105	1.007e-94	312.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA_2	-	2.7.4.1,2.7.6.5,3.1.7.2	ko:K00937,ko:K01139	ko00190,ko00230,ko03018,map00190,map00230,map03018	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	HD_4
HKD2_k127_1384611_3	290399.Arth_3985	5.727e-153	486.0	COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,1W7FH@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HKD2_k127_1384611_5	290399.Arth_3986	5.562e-82	274.0	COG1522@1|root,COG1522@2|Bacteria,2GKYC@201174|Actinobacteria,1WCAW@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD2_k127_1384611_6	1449044.JMLE01000014_gene2394	2.466e-69	237.0	COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria,1W9IT@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
HKD2_k127_1396373_1	1150398.JIBJ01000008_gene655	1.946e-54	196.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
HKD2_k127_1396373_2	290399.Arth_3734	8.493e-33	133.0	2ER8U@1|root,33IUE@2|Bacteria,2GXJ3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1396373_0	452863.Achl_3474	7.912e-106	344.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,1W8JC@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HKD2_k127_1401730_1	290399.Arth_2722	4.954e-119	385.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,1WB7C@1268|Micrococcaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HKD2_k127_1401730_0	1150398.JIBJ01000010_gene527	1.446e-191	611.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,1W7RX@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HKD2_k127_1417263_1	1108045.GORHZ_109_00030	2.741e-47	172.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1417263_0	1108045.GORHZ_109_00020	1.336e-134	443.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
HKD2_k127_1417263_2	653045.Strvi_6190	5.436e-12	67.0	COG1396@1|root,COG1396@2|Bacteria,2GJXM@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
HKD2_k127_1419147_1	1276920.ADIAG_00351	6.024e-44	166.0	COG1846@1|root,COG1846@2|Bacteria,2GTM4@201174|Actinobacteria,1W9Q4@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_1419147_0	1150398.JIBJ01000017_gene1432	2.068e-140	453.0	COG0421@1|root,COG0421@2|Bacteria,2GN8I@201174|Actinobacteria,1W910@1268|Micrococcaceae	201174|Actinobacteria	E	spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Spermine_synth
HKD2_k127_1419147_2	290399.Arth_2507	2.931e-41	152.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,1W8BA@1268|Micrococcaceae	201174|Actinobacteria	E	aminotransferase class I and II	dapC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.6.1.1,2.6.1.17,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260,ko:K14267	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R04475,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv0858c	Aminotran_1_2
HKD2_k127_1422059_6	1150398.JIBJ01000001_gene1385	8.661e-05	46.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1422059_0	1150398.JIBJ01000001_gene1387	7.955e-167	527.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,1W7UF@1268|Micrococcaceae	201174|Actinobacteria	S	PFAM aldo keto reductase	dkgA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
HKD2_k127_1422059_2	1150398.JIBJ01000001_gene1388	7.441e-69	238.0	28XC9@1|root,2ZJA5@2|Bacteria,2IRTE@201174|Actinobacteria,1W9Q5@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1422059_1	1449044.JMLE01000011_gene3405	2.754e-91	304.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria	201174|Actinobacteria	S	regulation of cellular protein catabolic process	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
HKD2_k127_1422059_4	1150398.JIBJ01000001_gene1390	3.43e-28	119.0	COG2879@1|root,COG2879@2|Bacteria,2HTC3@201174|Actinobacteria,1WA98@1268|Micrococcaceae	201174|Actinobacteria	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
HKD2_k127_1422059_3	1449044.JMLE01000011_gene3407	2.997e-41	153.0	COG1966@1|root,COG1966@2|Bacteria,2GIYX@201174|Actinobacteria,1W8N6@1268|Micrococcaceae	201174|Actinobacteria	T	Carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
HKD2_k127_1424860_2	290399.Arth_2152	3.543e-45	169.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
HKD2_k127_1424860_1	1150398.JIBJ01000013_gene2551	9.819e-49	185.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
HKD2_k127_1424860_0	1150398.JIBJ01000013_gene2552	1.015e-98	325.0	2DBXI@1|root,2ZBQ3@2|Bacteria,2GJN1@201174|Actinobacteria,1W9VX@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
HKD2_k127_1438510_2	1150398.JIBJ01000013_gene2517	1.013e-129	415.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,1W7NY@1268|Micrococcaceae	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
HKD2_k127_1438510_1	1150398.JIBJ01000013_gene2516	9.737e-155	500.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,1W9K5@1268|Micrococcaceae	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
HKD2_k127_1438510_3	1150398.JIBJ01000013_gene2515	3.081e-77	266.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,1W98Z@1268|Micrococcaceae	201174|Actinobacteria	O	peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HKD2_k127_1438510_0	1150398.JIBJ01000013_gene2514	7.619e-201	633.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,1W8EM@1268|Micrococcaceae	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
HKD2_k127_144018_4	1150398.JIBJ01000005_gene3360	1.223e-34	133.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
HKD2_k127_144018_1	290399.Arth_2905	8.698e-226	700.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,1W7X3@1268|Micrococcaceae	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
HKD2_k127_144018_2	1150398.JIBJ01000005_gene3358	1.838e-206	644.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,1W8QB@1268|Micrococcaceae	201174|Actinobacteria	C	aldo keto reductase	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
HKD2_k127_144018_0	1150398.JIBJ01000005_gene3357	0.0	1058.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,1W8KH@1268|Micrococcaceae	201174|Actinobacteria	G	4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase	treZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
HKD2_k127_144018_3	1150398.JIBJ01000005_gene3356	2.093e-206	647.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,1W8DQ@1268|Micrococcaceae	201174|Actinobacteria	G	synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
HKD2_k127_1440491_0	1077972.ARGLB_027_02000	2.807e-115	374.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,1W7ZC@1268|Micrococcaceae	201174|Actinobacteria	CH	Phenol hydroxylase, C-terminal dimerisation domain	-	-	1.14.13.7	ko:K03380	ko00623,ko00627,ko01120,map00623,map00627,map01120	-	R00815,R03566	RC00046,RC00236	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Phe_hydrox_dim
HKD2_k127_1440491_1	1150398.JIBJ01000023_gene3888	1.867e-104	341.0	COG0591@1|root,COG0591@2|Bacteria,2GKPW@201174|Actinobacteria,1W7UP@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD2_k127_1463598_8	290340.AAur_3980	0.0001651	44.0	COG1414@1|root,COG1414@2|Bacteria,2IPCZ@201174|Actinobacteria,1W9ER@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_1463598_1	1150398.JIBJ01000007_gene158	3.566e-155	498.0	COG1289@1|root,COG1289@2|Bacteria,2I8WS@201174|Actinobacteria,1WA58@1268|Micrococcaceae	201174|Actinobacteria	S	Fusaric acid resistance protein-like	yccS_2	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HKD2_k127_1463598_5	290399.Arth_4049	1.904e-70	241.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HKD2_k127_1463598_0	1150398.JIBJ01000007_gene162	3.27e-160	510.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,1W8Z0@1268|Micrococcaceae	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
HKD2_k127_1463598_2	1150398.JIBJ01000007_gene164	4e-130	419.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,1W8GD@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	pcaR	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
HKD2_k127_1463598_3	1150398.JIBJ01000007_gene165	1.021e-127	410.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,1W8QD@1268|Micrococcaceae	201174|Actinobacteria	I	CoA-transferase	scoB	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2503c	CoA_trans
HKD2_k127_1463598_4	1101188.KI912156_gene4146	9.379e-116	373.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,1W8HQ@1268|Micrococcaceae	201174|Actinobacteria	I	CoA-transferase	pcaI	-	2.8.3.6	ko:K01031	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_1470487_7	665577.JH993790_gene5792	1.614e-20	93.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve_3
HKD2_k127_1470487_6	479432.Sros_3573	5.762e-26	119.0	2EKKB@1|root,33EA6@2|Bacteria,2IMNJ@201174|Actinobacteria	201174|Actinobacteria	S	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
HKD2_k127_1470487_4	67352.JODS01000048_gene3448	1.295e-33	147.0	2EKKB@1|root,33EA6@2|Bacteria,2IMNJ@201174|Actinobacteria	201174|Actinobacteria	S	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
HKD2_k127_1470487_2	665577.JH993790_gene5728	2.884e-60	213.0	COG2842@1|root,COG2842@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,TniB
HKD2_k127_1470487_1	665577.JH993790_gene5728	4.93e-114	384.0	COG2842@1|root,COG2842@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,TniB
HKD2_k127_1470487_0	1054860.KB913030_gene693	1.651e-290	911.0	COG2801@1|root,COG2801@2|Bacteria,2HITH@201174|Actinobacteria	201174|Actinobacteria	L	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Mu-transpos_C,rve
HKD2_k127_1470487_5	1054860.KB913030_gene694	1.578e-27	115.0	2BSDG@1|root,32MFF@2|Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1470487_3	1054860.KB913030_gene694	3.164e-60	217.0	2BSDG@1|root,32MFF@2|Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1490228_1	1122138.AQUZ01000010_gene5126	6.293e-32	131.0	COG0596@1|root,COG0596@2|Bacteria,2GMYM@201174|Actinobacteria,4DTGY@85009|Propionibacteriales	201174|Actinobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
HKD2_k127_1490228_0	222534.KB893761_gene3419	1.294e-99	341.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4ESJG@85013|Frankiales	201174|Actinobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
HKD2_k127_1490228_2	1121877.JQKF01000006_gene925	1.391e-16	80.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
HKD2_k127_1536124_1	1150398.JIBJ01000010_gene572	5.579e-76	255.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,1W802@1268|Micrococcaceae	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD2_k127_1536124_0	290399.Arth_2665	3.758e-146	466.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,1W8F8@1268|Micrococcaceae	201174|Actinobacteria	D	cell division ATP-binding protein	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD2_k127_1536124_2	1150398.JIBJ01000010_gene574	9.119e-21	92.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,1W7DR@1268|Micrococcaceae	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD2_k127_1559863_0	1150398.JIBJ01000005_gene3371	4.55e-238	739.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,1W7HV@1268|Micrococcaceae	201174|Actinobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
HKD2_k127_1559863_1	290399.Arth_2890	6.289e-181	577.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,1W7HF@1268|Micrococcaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
HKD2_k127_1560956_0	886293.Sinac_2157	3.188e-223	699.0	COG3385@1|root,COG3385@2|Bacteria,2J0KK@203682|Planctomycetes	203682|Planctomycetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_1582981_5	930171.Asphe3_24500	3.339e-30	119.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,1W7ZQ@1268|Micrococcaceae	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
HKD2_k127_1582981_1	1449044.JMLE01000005_gene584	1.493e-111	362.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,1W8W0@1268|Micrococcaceae	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
HKD2_k127_1582981_0	290399.Arth_2586	6.135e-254	788.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,1W8D6@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
HKD2_k127_1582981_3	1197706.AKKK01000052_gene3526	5.125e-50	180.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,1W9U2@1268|Micrococcaceae	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
HKD2_k127_1582981_2	1150398.JIBJ01000015_gene1983	4.628e-97	323.0	2E4AX@1|root,32Z6K@2|Bacteria,2HT79@201174|Actinobacteria,1W9JM@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
HKD2_k127_1596691_2	1115632.JAFW01000001_gene3301	1.361e-94	310.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,1W7R4@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_1596691_0	1150398.JIBJ01000018_gene2226	1.935e-237	746.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,1W7H3@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_1596691_3	930171.Asphe3_08180	2.589e-38	149.0	COG4842@1|root,COG4842@2|Bacteria,2GQI8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the WXG100 family	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
HKD2_k127_1596691_1	290399.Arth_0781	4.551e-153	490.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,1W8WY@1268|Micrococcaceae	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
HKD2_k127_1596691_4	290399.Arth_0779	7.704e-12	64.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,1W8B0@1268|Micrococcaceae	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD2_k127_1604331_1	1217720.ALOX01000142_gene3559	6.159e-49	187.0	2ED3F@1|root,3370B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1604331_0	485913.Krac_9867	9.883e-126	410.0	28JEU@1|root,2Z98W@2|Bacteria,2G8M2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM MULE transposase, conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	MULE
HKD2_k127_1604331_2	794903.OPIT5_24175	6.365e-14	80.0	COG3464@1|root,COG3464@2|Bacteria,46TWJ@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
HKD2_k127_162362_5	762376.AXYL_00857	1.138e-154	498.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VN3E@28216|Betaproteobacteria,3T3CP@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
HKD2_k127_162362_10	1121952.ATXT01000011_gene2708	5.298e-86	291.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4FMU5@85023|Microbacteriaceae	201174|Actinobacteria	S	Uncharacterised protein family (UPF0014)	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
HKD2_k127_162362_1	1151119.KB895489_gene562	1.734e-306	957.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	acpA	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
HKD2_k127_162362_4	1151119.KB895489_gene563	1.9e-192	604.0	COG3391@1|root,COG3391@2|Bacteria,2IDP3@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_162362_12	1304876.AZVC01000004_gene3198	7.125e-69	237.0	COG1302@1|root,COG1302@2|Bacteria,2IMA3@201174|Actinobacteria,1W9D9@1268|Micrococcaceae	201174|Actinobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD2_k127_162362_21	1151118.KB895800_gene184	5.053e-24	102.0	2DED3@1|root,2ZMH1@2|Bacteria,2GXTN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2273
HKD2_k127_162362_14	1304876.AZVC01000004_gene3201	1.016e-59	213.0	2BXHQ@1|root,345PG@2|Bacteria,2GRQ5@201174|Actinobacteria,1WBCQ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_162362_13	1115632.JAFW01000001_gene2062	5.66e-64	234.0	2ASVE@1|root,31IAV@2|Bacteria,2GY33@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_162362_18	1158050.KB895453_gene1026	7.338e-27	111.0	COG3237@1|root,COG3237@2|Bacteria	2|Bacteria	K	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
HKD2_k127_162362_9	1304876.AZVC01000004_gene3204	9.26e-91	303.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,1WA3Q@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_162362_11	1115632.JAFW01000001_gene2065	1.655e-79	276.0	COG1302@1|root,COG1302@2|Bacteria,2IQBU@201174|Actinobacteria,1W9X9@1268|Micrococcaceae	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD2_k127_162362_8	1449044.JMLE01000003_gene2833	1.131e-92	316.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria,1W9CQ@1268|Micrococcaceae	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HKD2_k127_162362_7	1150398.JIBJ01000012_gene2138	7.334e-120	392.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	rsbQ	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
HKD2_k127_162362_6	1150398.JIBJ01000012_gene2137	4.998e-124	409.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
HKD2_k127_162362_17	930171.Asphe3_31690	2.695e-31	124.0	2DP23@1|root,3307G@2|Bacteria,2I053@201174|Actinobacteria,1WA7E@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2945)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2945
HKD2_k127_162362_3	1101188.KI912155_gene1034	2.159e-212	672.0	COG3979@1|root,COG3979@2|Bacteria,2I2XD@201174|Actinobacteria	201174|Actinobacteria	G	chitin binding	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
HKD2_k127_162362_0	1101188.KI912155_gene1033	0.0	1180.0	COG1215@1|root,COG1215@2|Bacteria,2GN8M@201174|Actinobacteria	201174|Actinobacteria	M	probably involved in cell wall	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Glyco_trans_2_3
HKD2_k127_162362_2	1158050.KB895453_gene977	8.006e-266	834.0	28IZ9@1|root,2Z8WS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
HKD2_k127_162362_15	1449044.JMLE01000003_gene2978	1.252e-44	164.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria,1WA3B@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HKD2_k127_1633522_4	290399.Arth_1440	7.06e-21	91.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,1W7G0@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HKD2_k127_1633522_3	1151119.KB895508_gene476	1.199e-38	145.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
HKD2_k127_1633522_1	1045009.AFXQ01000011_gene451	4.547e-95	327.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HKD2_k127_1633522_2	935839.JAGJ01000010_gene303	8.858e-89	300.0	COG1309@1|root,COG1309@2|Bacteria,2I0QC@201174|Actinobacteria,4F5BY@85017|Promicromonosporaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_1633522_0	1043205.AFYF01000058_gene2508	6.663e-173	555.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FFEK@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_1646533_1	1150864.MILUP08_42749	5.737e-15	79.0	COG3293@1|root,COG3293@2|Bacteria,2IHX5@201174|Actinobacteria,4DFFW@85008|Micromonosporales	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HKD2_k127_1646533_0	1246995.AFR_32850	9.657e-138	454.0	COG0654@1|root,COG0654@2|Bacteria,2I901@201174|Actinobacteria,4DJS1@85008|Micromonosporales	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_3,Trp_halogenase
HKD2_k127_1646533_2	882086.SacxiDRAFT_2349	1.195e-08	56.0	29WM0@1|root,30I7P@2|Bacteria,2HRZT@201174|Actinobacteria,4EBJQ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
HKD2_k127_1665874_2	1150398.JIBJ01000009_gene315	3.676e-88	294.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,1W98W@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HKD2_k127_1665874_1	1150398.JIBJ01000009_gene314	1.502e-107	355.0	2E4S1@1|root,32ZKH@2|Bacteria,2IHFD@201174|Actinobacteria,1W9IX@1268|Micrococcaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
HKD2_k127_1665874_0	1077972.ARGLB_098_00440	3.044e-219	688.0	COG0477@1|root,COG2814@2|Bacteria,2GJK6@201174|Actinobacteria,1W8RH@1268|Micrococcaceae	201174|Actinobacteria	EGP	drug resistance transporter, Bcr CflA subfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
HKD2_k127_1682113_1	930171.Asphe3_34120	9.536e-134	445.0	2CVPW@1|root,32SXZ@2|Bacteria,2ITC5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1682113_5	1151119.KB895498_gene3512	1.27e-38	155.0	2EIMI@1|root,33CCT@2|Bacteria,2GSNP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1682113_0	1449044.JMLE01000001_gene3829	2.71e-202	647.0	2EDNG@1|root,337I7@2|Bacteria,2ICQ2@201174|Actinobacteria,1W89N@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF5129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5129
HKD2_k127_1682113_4	1449044.JMLE01000001_gene3828	1.081e-55	197.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD2_k127_1682113_2	1150398.JIBJ01000004_gene2787	6.313e-87	291.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,1WCI9@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD2_k127_1682113_3	290399.Arth_2336	2.399e-84	289.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HKD2_k127_1692815_1	1077972.ARGLB_073_01470	1.435e-131	424.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,1W7MH@1268|Micrococcaceae	201174|Actinobacteria	CP	Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali	mrpA/mrpB	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
HKD2_k127_1692815_0	1449044.JMLE01000010_gene3626	5.658e-135	436.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,1W7Z0@1268|Micrococcaceae	201174|Actinobacteria	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD2_k127_1696568_3	1115632.JAFW01000001_gene676	2.285e-21	94.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,1W7RG@1268|Micrococcaceae	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
HKD2_k127_1696568_0	1150398.JIBJ01000015_gene2021	8.828e-221	686.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,1W7EH@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD2_k127_1696568_1	1150398.JIBJ01000015_gene2020	1.372e-167	537.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,1W8CR@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD2_k127_1696568_2	1150398.JIBJ01000015_gene2019	9.319e-33	131.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,1W8HC@1268|Micrococcaceae	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD2_k127_171060_3	1449044.JMLE01000007_gene1280	4.725e-49	181.0	2DSN0@1|root,33GQX@2|Bacteria,2HN6D@201174|Actinobacteria	201174|Actinobacteria	S	Small secreted domain (DUF320)	-	-	-	-	-	-	-	-	-	-	-	-	DUF320
HKD2_k127_171060_1	1151118.KB895783_gene4066	6.744e-263	844.0	COG0642@1|root,COG0642@2|Bacteria,2I58H@201174|Actinobacteria	201174|Actinobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
HKD2_k127_171060_2	1132441.KI519455_gene3568	6.249e-126	409.0	COG2199@1|root,COG3706@2|Bacteria,2ISZA@201174|Actinobacteria	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
HKD2_k127_171060_6	479435.Kfla_0904	2.291e-09	59.0	COG3237@1|root,COG3237@2|Bacteria,2I0D5@201174|Actinobacteria,4DSKR@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
HKD2_k127_171060_0	1150398.JIBJ01000002_gene1031	0.0	1171.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,1W8TR@1268|Micrococcaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Inhibitor_I9,PA,Peptidase_S8
HKD2_k127_1726908_0	1150398.JIBJ01000017_gene1421	5.536e-212	677.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,1W7K7@1268|Micrococcaceae	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD2_k127_1726908_1	1077972.ARGLB_093_00020	2.225e-92	305.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria,1W7G7@1268|Micrococcaceae	201174|Actinobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD2_k127_175730_0	1150398.JIBJ01000002_gene1159	1.305e-228	715.0	COG0025@1|root,COG0025@2|Bacteria,2GKCK@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD2_k127_175730_1	1150398.JIBJ01000002_gene1158	4.608e-137	439.0	COG0010@1|root,COG0010@2|Bacteria,2IA0Q@201174|Actinobacteria,1W89T@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD2_k127_1763055_3	1150398.JIBJ01000004_gene2622	1.051e-70	240.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,1W7JB@1268|Micrococcaceae	201174|Actinobacteria	I	Acyl transferase domain	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HKD2_k127_1763055_1	1150398.JIBJ01000004_gene2621	8.01e-198	619.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,1W7J6@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0019637,GO:0019693,GO:0019752,GO:0030497,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033818,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901568,GO:1901576,GO:1901681	2.3.1.180	ko:K00648,ko:K11608	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iNJ661.Rv0533c	ACP_syn_III,ACP_syn_III_C
HKD2_k127_1763055_5	1077972.ARGLB_111_00490	2.372e-40	152.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria,1W9NX@1268|Micrococcaceae	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD2_k127_1763055_0	1101188.KI912155_gene3762	2.118e-248	770.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,1W7RP@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HKD2_k127_1763055_2	1101188.KI912155_gene1015	2.653e-116	391.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,1W85W@1268|Micrococcaceae	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD2_k127_1763055_4	479435.Kfla_3609	9.719e-45	166.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4DNXZ@85009|Propionibacteriales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD2_k127_1800934_1	290399.Arth_1090	6.014e-137	437.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,1W8C7@1268|Micrococcaceae	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HKD2_k127_1800934_0	1150398.JIBJ01000006_gene3663	8.705e-138	441.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,1W8C7@1268|Micrococcaceae	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HKD2_k127_1805395_2	1449044.JMLE01000002_gene4460	2.874e-61	218.0	2BG96@1|root,32A69@2|Bacteria,2HC72@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1805395_0	1150398.JIBJ01000005_gene3255	2.945e-168	541.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,1W7NH@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
HKD2_k127_1805395_1	1150398.JIBJ01000005_gene3256	1.655e-91	302.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,1W85M@1268|Micrococcaceae	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD2_k127_1821528_1	1150398.JIBJ01000002_gene883	4.177e-251	781.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,1W87H@1268|Micrococcaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD2_k127_1821528_0	1449044.JMLE01000011_gene3421	0.0	1215.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,1W883@1268|Micrococcaceae	201174|Actinobacteria	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
HKD2_k127_1821528_2	1151119.KB895503_gene3080	1.766e-228	711.0	COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,2GKXT@201174|Actinobacteria,1W7G3@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the globin family	-	-	1.14.12.17	ko:K05916	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Globin,NAD_binding_1
HKD2_k127_1821528_5	1150398.JIBJ01000001_gene1407	1.236e-68	240.0	COG1959@1|root,COG1959@2|Bacteria,2IHTP@201174|Actinobacteria,1W9IN@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
HKD2_k127_1821528_4	1150398.JIBJ01000001_gene1406	1.577e-74	254.0	2EN55@1|root,33FT5@2|Bacteria,2GYVR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1821528_3	1150398.JIBJ01000001_gene1405	7.89e-91	299.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,1W7R2@1268|Micrococcaceae	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD2_k127_1826523_0	886293.Sinac_4767	2.966e-107	364.0	COG3464@1|root,COG3464@2|Bacteria,2IZV3@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Uncharacterised protein family (UPF0236)	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1826665_6	1151126.AQYI01000006_gene3056	2.695e-21	93.0	COG1670@1|root,COG1670@2|Bacteria,2IKZC@201174|Actinobacteria,4FPAZ@85023|Microbacteriaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HKD2_k127_1826665_3	1150398.JIBJ01000005_gene3213	1.199e-93	314.0	COG4242@1|root,COG4242@2|Bacteria,2IG1C@201174|Actinobacteria	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
HKD2_k127_1826665_2	290399.Arth_3069	9.263e-105	341.0	COG0824@1|root,COG0824@2|Bacteria,2IHBJ@201174|Actinobacteria,1W991@1268|Micrococcaceae	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
HKD2_k127_1826665_4	1150398.JIBJ01000005_gene3215	3.166e-77	259.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,1W9G6@1268|Micrococcaceae	201174|Actinobacteria	CO	Belongs to the thioredoxin family	trxA	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
HKD2_k127_1826665_5	1158050.KB895452_gene568	4.097e-46	169.0	COG1359@1|root,COG1359@2|Bacteria,2HPFG@201174|Actinobacteria,1WBR1@1268|Micrococcaceae	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD2_k127_1826665_0	1150398.JIBJ01000005_gene3217	0.0	1020.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,1W8MR@1268|Micrococcaceae	201174|Actinobacteria	IQ	AMP-binding enzyme	fadD35	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_1826665_1	1150398.JIBJ01000005_gene3219	5.641e-171	542.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria,1W88J@1268|Micrococcaceae	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1833054_2	1151119.KB895517_gene2715	4.362e-40	149.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,1W7IQ@1268|Micrococcaceae	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HKD2_k127_1833054_0	1150398.JIBJ01000004_gene3010	2.467e-190	601.0	COG0237@1|root,COG2320@1|root,COG0237@2|Bacteria,COG2320@2|Bacteria,2GN96@201174|Actinobacteria,1W8VX@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
HKD2_k127_1833054_1	290399.Arth_2068	3.229e-108	354.0	COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria,1W98F@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized protein family UPF0029	yigZ	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
HKD2_k127_1833054_3	1150398.JIBJ01000004_gene3008	2.139e-19	93.0	COG1670@1|root,COG1670@2|Bacteria,2GVK3@201174|Actinobacteria,1WBX7@1268|Micrococcaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD2_k127_1866392_3	1304876.AZVC01000015_gene3795	6.63e-73	247.0	COG2890@1|root,COG2890@2|Bacteria,2I3EW@201174|Actinobacteria,1WCE6@1268|Micrococcaceae	201174|Actinobacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1866392_1	1150398.JIBJ01000001_gene1370	2.338e-156	503.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,1W7PI@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
HKD2_k127_1866392_2	1449044.JMLE01000011_gene3382	1.053e-115	376.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,1W948@1268|Micrococcaceae	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HKD2_k127_1866392_0	290399.Arth_0723	1.283e-217	679.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,1W866@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD2_k127_1866392_4	1449044.JMLE01000011_gene3380	4.173e-27	110.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,1W7VB@1268|Micrococcaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_1869587_1	1150398.JIBJ01000003_gene1861	6.381e-109	356.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,1W7T7@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HKD2_k127_1869587_0	1449044.JMLE01000009_gene3239	2.681e-235	731.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,1W8FE@1268|Micrococcaceae	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
HKD2_k127_1870124_0	666681.M301_0435	0.0009521	49.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2VPQ6@28216|Betaproteobacteria	28216|Betaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
HKD2_k127_187533_3	1150398.JIBJ01000005_gene3386	2.618e-24	103.0	COG3346@1|root,COG3346@2|Bacteria,2GMGB@201174|Actinobacteria,1W995@1268|Micrococcaceae	201174|Actinobacteria	S	SURF1 family	-	-	-	-	-	-	-	-	-	-	-	-	SURF1
HKD2_k127_187533_2	1150398.JIBJ01000005_gene3387	3.722e-91	305.0	2E65S@1|root,330UF@2|Bacteria,2IMEQ@201174|Actinobacteria,1W8TQ@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3817
HKD2_k127_187533_0	1077972.ARGLB_085_02870	0.0	1020.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,1W87C@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HKD2_k127_187533_1	290399.Arth_2868	1.774e-288	893.0	COG1112@1|root,COG1196@1|root,COG1112@2|Bacteria,COG1196@2|Bacteria,2GKJW@201174|Actinobacteria,1W85U@1268|Micrococcaceae	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011
HKD2_k127_1888502_1	290399.Arth_1624	1.649e-89	300.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,1W88S@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
HKD2_k127_1888502_0	1158050.KB895452_gene677	1.033e-155	499.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria	201174|Actinobacteria	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HKD2_k127_189646_4	1150398.JIBJ01000006_gene3573	4.226e-136	435.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,1W822@1268|Micrococcaceae	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE1	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
HKD2_k127_189646_3	1150398.JIBJ01000006_gene3572	1.112e-167	543.0	COG2348@1|root,COG2348@2|Bacteria,2HURK@201174|Actinobacteria,1W7J3@1268|Micrococcaceae	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
HKD2_k127_189646_2	1150398.JIBJ01000006_gene3571	1.052e-195	617.0	COG1482@1|root,COG1482@2|Bacteria,2GJXC@201174|Actinobacteria,1W85R@1268|Micrococcaceae	201174|Actinobacteria	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
HKD2_k127_189646_0	1077972.ARGLB_010_00200	2.873e-256	807.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,1W7FP@1268|Micrococcaceae	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD2_k127_189646_6	1150398.JIBJ01000006_gene3569	1.23e-90	307.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,1W8XW@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
HKD2_k127_189646_1	290399.Arth_1189	8.946e-210	668.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,1W7U7@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
HKD2_k127_189646_5	452863.Achl_1261	3.142e-93	312.0	COG2246@1|root,COG2246@2|Bacteria,2IFFV@201174|Actinobacteria,1W9D3@1268|Micrococcaceae	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HKD2_k127_189646_7	1150398.JIBJ01000006_gene3566	1.29e-51	187.0	COG0365@1|root,COG0365@2|Bacteria,2I2IW@201174|Actinobacteria,1W9RG@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
HKD2_k127_19188_2	1449044.JMLE01000008_gene2213	6.561e-30	119.0	2E45J@1|root,32Z1K@2|Bacteria	2|Bacteria	S	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
HKD2_k127_19188_0	452863.Achl_1067	1.359e-168	534.0	COG0604@1|root,COG0604@2|Bacteria,2GIWC@201174|Actinobacteria,1W86E@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
HKD2_k127_19188_1	1150398.JIBJ01000002_gene1187	3.843e-63	221.0	COG3339@1|root,COG3339@2|Bacteria,2IMW8@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HKD2_k127_19188_3	1449044.JMLE01000008_gene2219	3.953e-21	94.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,1WC8W@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_1923914_1	1101188.KI912155_gene3202	2.408e-63	222.0	2C3KP@1|root,2Z802@2|Bacteria,2IFTZ@201174|Actinobacteria	201174|Actinobacteria	S	phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1923914_0	1150398.JIBJ01000004_gene2714	4.776e-148	471.0	COG0834@1|root,COG0834@2|Bacteria,2I3WP@201174|Actinobacteria,1W8T1@1268|Micrococcaceae	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	tcyA	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
HKD2_k127_1923914_2	290399.Arth_2344	3.921e-41	153.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,1W9JX@1268|Micrococcaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	tcyA/tcyB	-	-	ko:K02029,ko:K02030,ko:K02424,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1,SBP_bac_3
HKD2_k127_1933950_1	1150398.JIBJ01000010_gene497	9.221e-118	379.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,1W92Y@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	nudC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
HKD2_k127_1933950_0	1150398.JIBJ01000010_gene498	0.0	1044.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,1W8G0@1268|Micrococcaceae	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
HKD2_k127_1944733_1	1158050.KB895452_gene290	1.548e-146	466.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,1W7G1@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter permease	glnQ	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
HKD2_k127_1944733_0	1158050.KB895452_gene289	1.065e-172	543.0	COG0834@1|root,COG0834@2|Bacteria,2I2QA@201174|Actinobacteria,1WCI0@1268|Micrococcaceae	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD2_k127_194798_1	1150398.JIBJ01000013_gene2573	2.041e-284	876.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,1W7UN@1268|Micrococcaceae	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN_1	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
HKD2_k127_194798_3	1150398.JIBJ01000013_gene2572	1.139e-142	461.0	COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria,1W8ZS@1268|Micrococcaceae	201174|Actinobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
HKD2_k127_194798_0	1150398.JIBJ01000013_gene2571	0.0	1008.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,1W7QA@1268|Micrococcaceae	201174|Actinobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2
HKD2_k127_194798_2	1077972.ARGLB_058_00860	1.678e-192	605.0	COG2307@1|root,COG2307@2|Bacteria,2GN0T@201174|Actinobacteria,1W8H3@1268|Micrococcaceae	201174|Actinobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HKD2_k127_1952636_0	1150398.JIBJ01000009_gene430	4.511e-217	681.0	COG2271@1|root,COG2271@2|Bacteria,2I5T5@201174|Actinobacteria,1W8RF@1268|Micrococcaceae	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_1952636_1	1150398.JIBJ01000009_gene429	1.282e-134	434.0	COG1404@1|root,COG1404@2|Bacteria,2GMN0@201174|Actinobacteria,1W915@1268|Micrococcaceae	201174|Actinobacteria	O	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
HKD2_k127_1952636_2	1150398.JIBJ01000009_gene428	5.343e-102	332.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,1W7YA@1268|Micrococcaceae	201174|Actinobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD2_k127_1982959_1	1150398.JIBJ01000005_gene3156	6.638e-140	445.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,1W88R@1268|Micrococcaceae	201174|Actinobacteria	C	Tryptophan halogenase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
HKD2_k127_1982959_0	290399.Arth_3132	2.448e-152	483.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,1W7IB@1268|Micrococcaceae	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HKD2_k127_1982959_2	290399.Arth_3133	1.59e-91	304.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,1W8BF@1268|Micrococcaceae	201174|Actinobacteria	HQ	Isochorismate synthase	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
HKD2_k127_2069601_1	298655.KI912266_gene2696	1.495e-19	93.0	2E3FZ@1|root,32YET@2|Bacteria,2IGAC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2069601_0	106370.Francci3_1132	2.658e-118	388.0	COG1715@1|root,COG1715@2|Bacteria,2GP9K@201174|Actinobacteria,4ET9P@85013|Frankiales	201174|Actinobacteria	L	Restriction endonuclease	mrr	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
HKD2_k127_2069601_2	106370.Francci3_2058	5.036e-05	45.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4EWGM@85013|Frankiales	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_2099634_0	1150398.JIBJ01000002_gene948	4.354e-222	694.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,1W8KY@1268|Micrococcaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_2099634_2	1150398.JIBJ01000002_gene949	1.072e-140	451.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,1W8HY@1268|Micrococcaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_2099634_1	1150398.JIBJ01000002_gene950	2.947e-187	595.0	COG4833@1|root,COG4833@2|Bacteria,2GNQY@201174|Actinobacteria,1W91T@1268|Micrococcaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 76	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_76
HKD2_k127_2120201_3	1150398.JIBJ01000014_gene2367	3.047e-37	140.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,1W84D@1268|Micrococcaceae	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HKD2_k127_2120201_0	290399.Arth_1519	0.0	1125.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,1W7J1@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
HKD2_k127_2120201_1	290399.Arth_1520	4.327e-118	389.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,1W967@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HKD2_k127_2120201_2	1150398.JIBJ01000014_gene2370	4.697e-59	211.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,1W7NZ@1268|Micrococcaceae	201174|Actinobacteria	L	tyrosine recombinase	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_2125547_0	1150398.JIBJ01000027_gene10	1.493e-247	766.0	COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,1W7ZN@1268|Micrococcaceae	201174|Actinobacteria	KLT	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
HKD2_k127_2125547_1	1150398.JIBJ01000027_gene9	1.476e-79	265.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,1W80X@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
HKD2_k127_2155732_0	1035308.AQYY01000002_gene301	1.452e-69	242.0	COG1028@1|root,COG1028@2|Bacteria	1035308.AQYY01000002_gene301|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2155732_1	290399.Arth_4423	2.95e-59	214.0	COG1742@1|root,COG1742@2|Bacteria,2IKM8@201174|Actinobacteria	201174|Actinobacteria	K	UPF0060 membrane protein	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
HKD2_k127_2158958_0	1150398.JIBJ01000004_gene3015	0.0	1546.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,1W7JM@1268|Micrococcaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
HKD2_k127_2158958_2	1349820.M707_00165	3.758e-89	295.0	COG1247@1|root,COG1247@2|Bacteria,2IHSU@201174|Actinobacteria,1W9IM@1268|Micrococcaceae	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_2158958_1	1449044.JMLE01000001_gene4109	1.365e-168	538.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,1W8C0@1268|Micrococcaceae	201174|Actinobacteria	S	alpha/beta hydrolase fold	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD2_k127_2215997_1	222534.KB893718_gene2230	1.264e-26	114.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,4ETF6@85013|Frankiales	201174|Actinobacteria	S	Lsr2	lsr	-	-	-	-	-	-	-	-	-	-	-	Lsr2
HKD2_k127_2215997_0	574375.BAGA_09620	5.799e-72	251.0	COG1961@1|root,COG1961@2|Bacteria,1UZT3@1239|Firmicutes,4HCR8@91061|Bacilli,1ZQD4@1386|Bacillus	91061|Bacilli	L	Resolvase, N terminal domain	binR	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
HKD2_k127_2215997_2	1380347.JNII01000012_gene2644	0.0001491	49.0	COG0671@1|root,COG0671@2|Bacteria,2GNBT@201174|Actinobacteria,4EW70@85013|Frankiales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K06153,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_2220918_2	290399.Arth_1293	1.236e-44	179.0	COG1716@1|root,COG1716@2|Bacteria,2GPZ0@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
HKD2_k127_2220918_0	290399.Arth_1292	3.455e-130	424.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,1W93Y@1268|Micrococcaceae	201174|Actinobacteria	T	phosphatase	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
HKD2_k127_2220918_1	1449044.JMLE01000046_gene2620	2.946e-89	299.0	COG1714@1|root,COG1716@1|root,COG1714@2|Bacteria,COG1716@2|Bacteria,2GSMX@201174|Actinobacteria	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD
HKD2_k127_2291533_1	1150398.JIBJ01000006_gene3477	5.547e-172	542.0	COG0583@1|root,COG0583@2|Bacteria,2GNFT@201174|Actinobacteria,1W8T4@1268|Micrococcaceae	201174|Actinobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_2291533_0	290399.Arth_1308	7.502e-210	653.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,1W8CD@1268|Micrococcaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HKD2_k127_229167_1	1150398.JIBJ01000006_gene3662	3.034e-73	252.0	COG3591@1|root,COG3591@2|Bacteria,2GJVS@201174|Actinobacteria,1WA3M@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_229167_0	1150398.JIBJ01000006_gene3661	7.326e-174	547.0	COG2838@1|root,COG2838@2|Bacteria,2GJ1C@201174|Actinobacteria,1W7SJ@1268|Micrococcaceae	201174|Actinobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
HKD2_k127_2294567_0	1150398.JIBJ01000009_gene438	1.558e-210	657.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,1W825@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	araJ	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
HKD2_k127_2294567_1	1077972.ARGLB_016_00250	3.022e-62	216.0	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria,1W9UG@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD2_k127_2307585_6	1150398.JIBJ01000004_gene2936	1.035e-102	340.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,1W7VV@1268|Micrococcaceae	201174|Actinobacteria	S	Transporter associated domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD2_k127_2307585_7	1449044.JMLE01000001_gene3943	8.02e-89	302.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,1W9B8@1268|Micrococcaceae	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
HKD2_k127_2307585_1	1158050.KB895454_gene1416	6.342e-215	671.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,1W8BK@1268|Micrococcaceae	201174|Actinobacteria	T	Phosphate starvation-inducible protein PhoH	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HKD2_k127_2307585_4	1150398.JIBJ01000004_gene2927	2.336e-137	458.0	COG5401@1|root,COG5401@2|Bacteria,2IRT5@201174|Actinobacteria,1W9P9@1268|Micrococcaceae	201174|Actinobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
HKD2_k127_2307585_5	1150398.JIBJ01000004_gene2926	4.883e-127	410.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,1W94X@1268|Micrococcaceae	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HKD2_k127_2307585_0	1150398.JIBJ01000004_gene2925	6.189e-229	711.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,1W7PJ@1268|Micrococcaceae	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD2_k127_2307585_2	1150398.JIBJ01000004_gene2924	1.418e-190	598.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,1W7MM@1268|Micrococcaceae	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
HKD2_k127_2307585_3	290399.Arth_2237	4.175e-168	529.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria,1W7MC@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
HKD2_k127_2307585_8	1150398.JIBJ01000004_gene2922	6.661e-78	266.0	COG3296@1|root,COG3296@2|Bacteria,2INY7@201174|Actinobacteria,1W9I2@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
HKD2_k127_2307585_9	1150398.JIBJ01000004_gene2921	6.909e-38	142.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,1W8BU@1268|Micrococcaceae	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
HKD2_k127_2394442_0	290399.Arth_3005	1.279e-266	824.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria,1WCEH@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_2394442_2	1150398.JIBJ01000005_gene3267	1.998e-125	404.0	COG1670@1|root,COG1670@2|Bacteria,2IRHX@201174|Actinobacteria,1W9UM@1268|Micrococcaceae	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,GNAT_acetyltran
HKD2_k127_2394442_1	290399.Arth_3003	5.883e-212	662.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,1W7HM@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HKD2_k127_2394442_4	290399.Arth_3002	7.025e-39	145.0	COG1983@1|root,COG1983@2|Bacteria,2HTBA@201174|Actinobacteria,1WA6M@1268|Micrococcaceae	201174|Actinobacteria	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
HKD2_k127_2394442_5	1077972.ARGLB_078_00720	3.875e-26	109.0	2DS6T@1|root,33ET5@2|Bacteria,2GZNW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2394442_3	1449044.JMLE01000002_gene4444	7.312e-57	201.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,1WA6U@1268|Micrococcaceae	201174|Actinobacteria	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
HKD2_k127_241449_1	1312959.KI914621_gene2441	5.157e-101	335.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,1W8KS@1268|Micrococcaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD2_k127_241449_0	1150398.JIBJ01000004_gene3024	2.64e-177	560.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,1W7F5@1268|Micrococcaceae	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HKD2_k127_241449_2	1150398.JIBJ01000004_gene3025	1.749e-93	325.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,1W7JT@1268|Micrococcaceae	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
HKD2_k127_2435202_2	448385.sce8449	1.193e-28	125.0	2ER00@1|root,33IJJ@2|Bacteria,1QAX2@1224|Proteobacteria,435CD@68525|delta/epsilon subdivisions,2WZPY@28221|Deltaproteobacteria,2Z2HP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2435202_0	448385.sce1047	9.996e-88	302.0	COG3011@1|root,COG3011@2|Bacteria,1Q9T0@1224|Proteobacteria,431NY@68525|delta/epsilon subdivisions,2WWMA@28221|Deltaproteobacteria,2YW28@29|Myxococcales	28221|Deltaproteobacteria	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
HKD2_k127_24385_2	1150398.JIBJ01000005_gene3354	9.934e-34	131.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,1W7JK@1268|Micrococcaceae	201174|Actinobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HKD2_k127_24385_1	1115632.JAFW01000001_gene956	1.05e-67	230.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,1W9BG@1268|Micrococcaceae	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
HKD2_k127_24385_0	1150398.JIBJ01000005_gene3352	9.699e-177	555.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,1W7GJ@1268|Micrococcaceae	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
HKD2_k127_243911_2	1194165.CAJF01000011_gene1095	8.822e-89	293.0	COG0346@1|root,COG0346@2|Bacteria,2GKY9@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	pheB	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HKD2_k127_243911_0	1177594.MIC448_1100038	3.565e-240	758.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FM3X@85023|Microbacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146,ko:K11947	ko00360,ko00624,ko00643,ko01100,ko01120,ko01220,map00360,map00624,map00643,map01100,map01120,map01220	-	R02536,R05649	RC00075,RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD2_k127_243911_1	1177594.MIC448_1100040	1.462e-116	379.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HKD2_k127_2440450_1	452863.Achl_2143	5.724e-118	381.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,1W7QI@1268|Micrococcaceae	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HKD2_k127_2440450_3	1158050.KB895454_gene1593	4.897e-49	175.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,1W9T0@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD2_k127_2440450_2	1150398.JIBJ01000004_gene2705	2.405e-56	197.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,1W9HB@1268|Micrococcaceae	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HKD2_k127_2440450_0	1150398.JIBJ01000004_gene2704	2.861e-226	719.0	COG0351@1|root,COG0819@1|root,COG0351@2|Bacteria,COG0819@2|Bacteria,2GKZM@201174|Actinobacteria,1W81E@1268|Micrococcaceae	201174|Actinobacteria	HK	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TENA_THI-4,TMP-TENI
HKD2_k127_2460153_1	1150398.JIBJ01000004_gene2869	7.171e-250	773.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,1W8HG@1268|Micrococcaceae	201174|Actinobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD2_k127_2460153_2	1449044.JMLE01000001_gene3891	1.674e-123	397.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,1W84W@1268|Micrococcaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD2_k127_2460153_3	1151118.KB895785_gene2732	6.2e-58	203.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,1W9K6@1268|Micrococcaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
HKD2_k127_2460153_4	1077972.ARGLB_039_00490	1.326e-31	125.0	2EGGE@1|root,33A8E@2|Bacteria,2GWWR@201174|Actinobacteria,1WBZG@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2460153_0	290399.Arth_2278	0.0	1162.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,1W7GQ@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD2_k127_2474752_4	290399.Arth_2461	1.294e-79	269.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,1W7PF@1268|Micrococcaceae	201174|Actinobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
HKD2_k127_2474752_3	1150398.JIBJ01000004_gene2626	1.69e-80	275.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,1W9SJ@1268|Micrococcaceae	201174|Actinobacteria	O	Redoxin	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
HKD2_k127_2474752_5	1449044.JMLE01000001_gene3694	1.041e-75	255.0	2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria,1W9EK@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
HKD2_k127_2474752_0	1150398.JIBJ01000004_gene2624	0.0	1797.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,1W7Q7@1268|Micrococcaceae	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD2_k127_2474752_1	290399.Arth_2465	1.481e-238	741.0	COG3835@1|root,COG3835@2|Bacteria,2I2QR@201174|Actinobacteria,1W7QU@1268|Micrococcaceae	201174|Actinobacteria	KT	PucR C-terminal helix-turn-helix domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	HTH_30
HKD2_k127_2474752_2	290399.Arth_2466	2.365e-144	461.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,1W7JB@1268|Micrococcaceae	201174|Actinobacteria	I	Acyl transferase domain	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HKD2_k127_2531125_1	1158050.KB895473_gene2729	6.102e-187	587.0	COG1840@1|root,COG1840@2|Bacteria,2IFVP@201174|Actinobacteria	201174|Actinobacteria	P	COG1840 ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_8
HKD2_k127_2531125_0	1158050.KB895473_gene2730	2.92e-213	667.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1,SBP_bac_6
HKD2_k127_2560486_2	1077972.ARGLB_010_00520	1.184e-136	436.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
HKD2_k127_2560486_0	290399.Arth_1157	1.197e-195	611.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_2560486_1	930171.Asphe3_11890	1.221e-180	567.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,1W9SW@1268|Micrococcaceae	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HKD2_k127_2567057_4	1077972.ARGLB_008_00820	6.443e-83	283.0	COG1716@1|root,COG1716@2|Bacteria,2GSQ0@201174|Actinobacteria,1WA0P@1268|Micrococcaceae	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2567057_5	1150398.JIBJ01000005_gene3063	3.049e-52	193.0	298Q5@1|root,30J5X@2|Bacteria,2GWQN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2567057_2	290399.Arth_3294	2.473e-105	344.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,1W958@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD2_k127_2567057_0	1077972.ARGLB_008_00780	4.623e-115	374.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,1W8DI@1268|Micrococcaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HKD2_k127_2567057_3	1150398.JIBJ01000005_gene3066	9.405e-103	340.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,1W930@1268|Micrococcaceae	201174|Actinobacteria	CO	Redoxin	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HKD2_k127_2567057_1	1349820.M707_20505	3.105e-108	352.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,1W7K5@1268|Micrococcaceae	201174|Actinobacteria	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
HKD2_k127_2569382_4	1151118.KB895808_gene2089	7.231e-24	111.0	COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_2569382_3	1077972.ARGLB_092_00750	5.646e-78	268.0	COG0684@1|root,COG0684@2|Bacteria,2IHQY@201174|Actinobacteria,1W9EE@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	rraA	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
HKD2_k127_2569382_0	1150398.JIBJ01000007_gene118	2.03e-322	990.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,1W8KZ@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_2569382_1	1150398.JIBJ01000007_gene119	2.485e-278	859.0	COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,1W86M@1268|Micrococcaceae	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	gtr	-	-	ko:K08139	ko04113,map04113	-	-	-	ko00000,ko00001,ko02000	2.A.1.1	-	-	Sugar_tr
HKD2_k127_2569382_2	1150398.JIBJ01000007_gene120	7.739e-145	460.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,1W80M@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	yfmO	-	-	ko:K08221	-	-	-	-	ko00000,ko02000	2.A.1.32	-	-	MFS_1
HKD2_k127_2575296_2	1150398.JIBJ01000013_gene2570	3.794e-145	462.0	COG2307@1|root,COG2307@2|Bacteria,2GN0T@201174|Actinobacteria,1W8H3@1268|Micrococcaceae	201174|Actinobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HKD2_k127_2575296_1	1150398.JIBJ01000013_gene2569	1.695e-179	563.0	COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria,1W7XD@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
HKD2_k127_2575296_4	290399.Arth_2134	2.521e-98	325.0	COG3467@1|root,COG3467@2|Bacteria,2IP5U@201174|Actinobacteria,1W9TE@1268|Micrococcaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
HKD2_k127_2575296_0	1150398.JIBJ01000013_gene2567	2.107e-248	778.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	devS	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
HKD2_k127_2575296_3	1150398.JIBJ01000013_gene2566	2.608e-115	379.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD2_k127_2575473_1	1150398.JIBJ01000004_gene2858	1.627e-141	454.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,1W83M@1268|Micrococcaceae	201174|Actinobacteria	J	Histidine--tRNA ligase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HKD2_k127_2575473_2	290399.Arth_2294	1.682e-134	433.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,1W8HR@1268|Micrococcaceae	201174|Actinobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HKD2_k127_2575473_0	1449044.JMLE01000001_gene3872	6.164e-226	707.0	COG3266@1|root,COG3266@2|Bacteria,2I2EC@201174|Actinobacteria,1W81Z@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
HKD2_k127_2583131_0	1150398.JIBJ01000008_gene800	4.128e-217	678.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,2GM5R@201174|Actinobacteria,1W848@1268|Micrococcaceae	201174|Actinobacteria	CE	Belongs to the aldehyde dehydrogenase family	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
HKD2_k127_2584929_0	1150398.JIBJ01000005_gene3414	7.746e-145	463.0	COG2971@1|root,COG2971@2|Bacteria,2GKNB@201174|Actinobacteria,1W9AX@1268|Micrococcaceae	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD2_k127_2584929_1	1150398.JIBJ01000005_gene3413	2.667e-91	306.0	COG2070@1|root,COG2070@2|Bacteria,2GKV4@201174|Actinobacteria,1W92J@1268|Micrococcaceae	201174|Actinobacteria	F	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
HKD2_k127_2585395_0	930171.Asphe3_31750	1.596e-162	512.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,1W8AE@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
HKD2_k127_2585395_1	1150398.JIBJ01000005_gene3114	1.504e-112	370.0	COG1309@1|root,COG1309@2|Bacteria,2GJZJ@201174|Actinobacteria,1W96V@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_2585395_2	290399.Arth_3251	2.06e-45	164.0	COG0346@1|root,COG0346@2|Bacteria,2IRYS@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD2_k127_2586468_1	1077972.ARGLB_073_00930	5.83e-82	276.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria,1W7ZZ@1268|Micrococcaceae	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
HKD2_k127_2586468_0	1150398.JIBJ01000002_gene942	1.429e-298	922.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,1W8AK@1268|Micrococcaceae	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
HKD2_k127_2602156_0	290399.Arth_3849	4.429e-150	477.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,1W7GH@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HKD2_k127_2602156_1	1150398.JIBJ01000008_gene754	2.069e-122	395.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,1W82S@1268|Micrococcaceae	201174|Actinobacteria	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
HKD2_k127_2626550_3	1312959.KI914690_gene2823	7.26e-24	110.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.255	ko:K20791	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
HKD2_k127_2626550_1	930171.Asphe3_04750	3.174e-123	402.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,1W9DS@1268|Micrococcaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
HKD2_k127_2626550_2	1077972.ARGLB_069_00780	1.399e-63	227.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria	201174|Actinobacteria	L	Pfam NUDIX	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_2626550_0	1150398.JIBJ01000004_gene2741	1.309e-214	673.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,1W83C@1268|Micrococcaceae	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD2_k127_2632769_0	1150398.JIBJ01000002_gene1115	8.979e-272	846.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,1WAR6@1268|Micrococcaceae	201174|Actinobacteria	T	Domain of unknown function (DUF4118)	kdpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
HKD2_k127_2632769_1	1150398.JIBJ01000002_gene1116	6.855e-109	382.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,1W8XG@1268|Micrococcaceae	201174|Actinobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_2632769_3	1158050.KB895452_gene645	4.199e-38	152.0	COG1846@1|root,COG1846@2|Bacteria,2IKTI@201174|Actinobacteria,1W9DT@1268|Micrococcaceae	201174|Actinobacteria	K	Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_2632769_2	1150398.JIBJ01000002_gene1117	3.121e-67	236.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,2I3N8@201174|Actinobacteria	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
HKD2_k127_2640500_0	1150398.JIBJ01000007_gene259	1.492e-277	857.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,1W7RY@1268|Micrococcaceae	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
HKD2_k127_2640500_1	1150398.JIBJ01000007_gene258	1.201e-185	582.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,1W7XS@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HKD2_k127_26435_0	1150398.JIBJ01000013_gene2528	6.207e-224	697.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,1W861@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
HKD2_k127_26435_1	1150398.JIBJ01000013_gene2526	2.788e-178	560.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,1W7XB@1268|Micrococcaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
HKD2_k127_26435_2	290399.Arth_2170	2.661e-118	384.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,1W7R1@1268|Micrococcaceae	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HKD2_k127_26435_3	1150398.JIBJ01000013_gene2524	5.617e-08	56.0	COG1994@1|root,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,1W93K@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
HKD2_k127_2652915_6	1449044.JMLE01000035_gene466	3.545e-17	86.0	COG2227@1|root,COG2227@2|Bacteria,2H9ND@201174|Actinobacteria,1WA5S@1268|Micrococcaceae	201174|Actinobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD2_k127_2652915_3	1123024.AUII01000013_gene451	2.439e-168	541.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4E8KN@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_2652915_5	1123258.AQXZ01000018_gene734	3.221e-66	236.0	COG2197@1|root,COG2197@2|Bacteria,2GM7Y@201174|Actinobacteria,4FUI4@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K21685	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,GerE
HKD2_k127_2652915_4	1150398.JIBJ01000002_gene1120	1.185e-88	298.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,1W986@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_2652915_0	290399.Arth_0433	0.0	1084.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,1W82Q@1268|Micrococcaceae	201174|Actinobacteria	I	synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_2652915_1	290399.Arth_0434	3.63e-222	694.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,1W7H7@1268|Micrococcaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE2	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_2652915_2	1150398.JIBJ01000002_gene1117	6.352e-201	633.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,2I3N8@201174|Actinobacteria	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
HKD2_k127_2652995_2	290399.Arth_3083	3.307e-90	299.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria,1W7Z8@1268|Micrococcaceae	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
HKD2_k127_2652995_1	290399.Arth_3082	3.564e-131	427.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria,1W8V5@1268|Micrococcaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HKD2_k127_2652995_3	1169161.KB897716_gene5850	2.312e-88	308.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HKD2_k127_2652995_0	290399.Arth_3080	6.581e-161	509.0	COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,1WCHY@1268|Micrococcaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_2653016_1	1449044.JMLE01000046_gene2622	1.815e-92	316.0	COG1716@1|root,COG1716@2|Bacteria,2GPZ0@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
HKD2_k127_2653016_0	290399.Arth_1294	1.06e-181	572.0	COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,1WAQV@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HKD2_k127_2670559_4	290399.Arth_2849	4.019e-77	287.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,1WB4B@1268|Micrococcaceae	201174|Actinobacteria	H	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HKD2_k127_2670559_3	1449044.JMLE01000002_gene4290	2.239e-88	304.0	COG1522@1|root,COG1522@2|Bacteria,2GMSR@201174|Actinobacteria,1W9AV@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD2_k127_2670559_0	1150398.JIBJ01000005_gene3408	9.877e-209	656.0	COG0477@1|root,COG2814@2|Bacteria,2I2P6@201174|Actinobacteria,1WAB4@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_2670559_2	290399.Arth_2854	2.075e-93	308.0	COG1522@1|root,COG1522@2|Bacteria,2GKYC@201174|Actinobacteria,1W9AH@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD2_k127_2670559_1	1150398.JIBJ01000005_gene3406	1.957e-195	613.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,1W7Y5@1268|Micrococcaceae	201174|Actinobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD2_k127_2670559_5	378753.KRH_12690	2.398e-17	86.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,1W8BJ@1268|Micrococcaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
HKD2_k127_2677693_4	1158050.KB895463_gene3790	1.753e-56	198.0	COG1832@1|root,COG1832@2|Bacteria,2GT41@201174|Actinobacteria,1W9GV@1268|Micrococcaceae	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
HKD2_k127_2677693_3	494419.ALPM01000077_gene1632	5.432e-114	374.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,1W8F2@1268|Micrococcaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ssuB	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
HKD2_k127_2677693_1	1312954.KI914857_gene1278	4.164e-137	460.0	COG0715@1|root,COG0715@2|Bacteria,2GMEC@201174|Actinobacteria,1W7EK@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter substrate-binding protein	-	-	-	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	NMT1
HKD2_k127_2677693_2	494419.ALPM01000077_gene1634	4.078e-124	404.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,1W8T5@1268|Micrococcaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	ssuC	-	-	ko:K15554	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	BPD_transp_1
HKD2_k127_2677693_0	1150398.JIBJ01000002_gene1048	1.18e-196	634.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,1W8BD@1268|Micrococcaceae	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD2_k127_2679843_0	1197706.AKKK01000025_gene2985	4.645e-188	596.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,1W8GA@1268|Micrococcaceae	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HKD2_k127_2679843_1	1449044.JMLE01000044_gene531	2.654e-68	238.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,1W815@1268|Micrococcaceae	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,TspO_MBR
HKD2_k127_2689222_1	1449044.JMLE01000020_gene1852	2.418e-80	269.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,1W8Z3@1268|Micrococcaceae	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
HKD2_k127_2689222_0	290399.Arth_1502	4.63e-242	748.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,1W8DZ@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
HKD2_k127_2711846_2	290399.Arth_3371	5.381e-54	201.0	COG4965@1|root,COG4965@2|Bacteria,2I0QG@201174|Actinobacteria,1W9JZ@1268|Micrococcaceae	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HKD2_k127_2711846_0	1150398.JIBJ01000024_gene3928	3.462e-183	591.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,1W8DR@1268|Micrococcaceae	201174|Actinobacteria	U	Secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
HKD2_k127_2711846_1	1077972.ARGLB_008_01400	7.627e-140	455.0	COG0455@1|root,COG0455@2|Bacteria,2GIVN@201174|Actinobacteria,1W9WT@1268|Micrococcaceae	201174|Actinobacteria	D	bacterial-type flagellum organization	cpaE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CbiA
HKD2_k127_2712444_0	290399.Arth_2211	4.118e-202	631.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,1W82C@1268|Micrococcaceae	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
HKD2_k127_2712444_2	1449044.JMLE01000001_gene3964	4.043e-149	475.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,1W835@1268|Micrococcaceae	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
HKD2_k127_2712444_3	1077972.ARGLB_039_01270	1.801e-131	441.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,1W7VA@1268|Micrococcaceae	201174|Actinobacteria	C	cytochrome c oxidase, subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
HKD2_k127_2712444_1	1150398.JIBJ01000004_gene2959	4.281e-181	571.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,1W7SK@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
HKD2_k127_2712444_7	290399.Arth_2207	9.2e-50	179.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,1W9QU@1268|Micrococcaceae	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
HKD2_k127_2712444_6	1150398.JIBJ01000004_gene2961	6.068e-54	192.0	2E6D0@1|root,3310N@2|Bacteria,2GQP8@201174|Actinobacteria,1WA0I@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
HKD2_k127_2712444_5	290399.Arth_0076	1.847e-81	286.0	COG1335@1|root,COG1335@2|Bacteria,2IG6Q@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HKD2_k127_2712444_9	262543.Exig_0529	8.179e-48	175.0	COG1942@1|root,COG1942@2|Bacteria,1V3SS@1239|Firmicutes,4HI9G@91061|Bacilli	91061|Bacilli	S	tautomerase	yodA	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
HKD2_k127_2712444_8	1312959.KI914695_gene2742	9.85e-50	180.0	COG0640@1|root,COG0640@2|Bacteria,2IM0G@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	kmtR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD2_k127_2712444_4	1150399.AQYK01000002_gene3263	1.732e-103	349.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4FM9J@85023|Microbacteriaceae	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD2_k127_2730704_2	1077972.ARGLB_051_01750	3.358e-09	58.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,1W7J1@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
HKD2_k127_2730704_0	1150398.JIBJ01000014_gene2367	7.018e-309	953.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,1W84D@1268|Micrococcaceae	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HKD2_k127_2730704_1	1150398.JIBJ01000014_gene2366	8.125e-136	433.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,1W7J2@1268|Micrococcaceae	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HKD2_k127_2734690_2	1150398.JIBJ01000004_gene2850	1.637e-154	489.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,1W8CX@1268|Micrococcaceae	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HKD2_k127_2734690_4	1150398.JIBJ01000004_gene2851	2.546e-62	217.0	COG1862@1|root,COG1862@2|Bacteria,2GPDR@201174|Actinobacteria,1W9WY@1268|Micrococcaceae	201174|Actinobacteria	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HKD2_k127_2734690_0	290399.Arth_2299	0.0	1011.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,1W7SG@1268|Micrococcaceae	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD2_k127_2734690_1	290399.Arth_2298	2.355e-181	571.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,1W888@1268|Micrococcaceae	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD2_k127_2734690_3	290399.Arth_2297	6.992e-140	447.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,1W7JR@1268|Micrococcaceae	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD2_k127_2740254_1	1150398.JIBJ01000006_gene3606	3.625e-68	233.0	COG3153@1|root,COG3602@1|root,COG3153@2|Bacteria,COG3602@2|Bacteria,2IM16@201174|Actinobacteria	201174|Actinobacteria	S	ACT domain	-	-	-	ko:K09964	-	-	-	-	ko00000	-	-	-	ACT_3,ACT_7,Acetyltransf_1
HKD2_k127_2740254_0	290399.Arth_1154	2.243e-252	784.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD2_k127_2748055_0	1150398.JIBJ01000005_gene3059	5.494e-150	477.0	COG0560@1|root,COG0560@2|Bacteria,2GJW9@201174|Actinobacteria,1W7V2@1268|Micrococcaceae	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB1	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HAD
HKD2_k127_2748055_2	1150398.JIBJ01000005_gene3060	1.013e-33	131.0	COG0695@1|root,COG0695@2|Bacteria,2I598@201174|Actinobacteria,1W9Z3@1268|Micrococcaceae	201174|Actinobacteria	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
HKD2_k127_2748055_1	1449044.JMLE01000004_gene2535	2.933e-119	387.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,1W8PD@1268|Micrococcaceae	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HKD2_k127_2782371_5	288705.RSal33209_3558	2.573e-12	66.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,1WA9W@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD2_k127_2782371_0	290399.Arth_0001	8.454e-292	900.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,1W7KZ@1268|Micrococcaceae	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
HKD2_k127_2782371_1	1150398.JIBJ01000007_gene240	1.359e-230	717.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,1W83N@1268|Micrococcaceae	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HKD2_k127_2782371_3	290399.Arth_0003	2.552e-178	564.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,1W8GC@1268|Micrococcaceae	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
HKD2_k127_2782371_2	290399.Arth_0004	1.099e-219	687.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,1W87X@1268|Micrococcaceae	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HKD2_k127_2782371_4	1150398.JIBJ01000007_gene243	3.45e-50	179.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,1W9C5@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
HKD2_k127_2790878_4	1150398.JIBJ01000009_gene438	1.679e-29	117.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,1W825@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	araJ	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
HKD2_k127_2790878_0	1150398.JIBJ01000009_gene437	5.687e-158	505.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,1WAXQ@1268|Micrococcaceae	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD2_k127_2790878_2	290399.Arth_1481	2.397e-47	171.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,1WA7N@1268|Micrococcaceae	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
HKD2_k127_2790878_1	930171.Asphe3_14640	4.096e-144	461.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,1W7S9@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD2_k127_2790878_3	1150398.JIBJ01000009_gene434	8.771e-41	152.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,1W95P@1268|Micrococcaceae	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD2_k127_2795544_1	290399.Arth_1580	6.797e-47	168.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,1W7MK@1268|Micrococcaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD2_k127_2795544_0	1150398.JIBJ01000014_gene2447	0.0	1013.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,1W7G6@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HKD2_k127_28081_3	1449044.JMLE01000014_gene2360	2.172e-172	542.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,1W7MS@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_28081_0	1150398.JIBJ01000007_gene139	2.915e-275	855.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	4CL	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_28081_6	1150398.JIBJ01000007_gene138	1.548e-66	229.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria	201174|Actinobacteria	T	universal stress protein	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD2_k127_28081_1	1150398.JIBJ01000007_gene137	1.028e-253	785.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,1W81W@1268|Micrococcaceae	201174|Actinobacteria	EK	aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HKD2_k127_28081_4	452863.Achl_3810	1.509e-97	321.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria	201174|Actinobacteria	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD2_k127_28081_5	290399.Arth_4018	2.532e-87	297.0	COG1309@1|root,COG1309@2|Bacteria,2GRIJ@201174|Actinobacteria,1WBRT@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_28081_2	290399.Arth_4017	6.446e-203	632.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,1W8RI@1268|Micrococcaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppB1	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD2_k127_28081_8	1449044.JMLE01000014_gene2371	8.031e-35	142.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,1W8QG@1268|Micrococcaceae	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HKD2_k127_2810250_1	930171.Asphe3_06200	9.442e-36	136.0	COG0412@1|root,COG0412@2|Bacteria,2GJMH@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	cmbl	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
HKD2_k127_2810250_0	1449044.JMLE01000011_gene3484	4.607e-269	829.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,1W82N@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HKD2_k127_2818518_0	1299327.I546_7208	2.788e-188	594.0	COG4974@1|root,COG4974@2|Bacteria,2GN10@201174|Actinobacteria,23FBC@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_2834829_3	1210884.HG799464_gene10927	1.178e-17	86.0	COG5433@1|root,COG5433@2|Bacteria,2J33P@203682|Planctomycetes	2|Bacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_2834829_2	1122138.AQUZ01000083_gene3524	7.048e-30	128.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4DUHR@85009|Propionibacteriales	201174|Actinobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_2834829_0	1123508.JH636444_gene5638	1.548e-76	265.0	COG3335@1|root,COG3335@2|Bacteria,2J2S1@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
HKD2_k127_2834829_1	1210884.HG799464_gene10935	3.091e-61	216.0	COG3415@1|root,COG3415@2|Bacteria,2J37P@203682|Planctomycetes	203682|Planctomycetes	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_33
HKD2_k127_2834829_4	595460.RRSWK_02302	2.901e-12	79.0	2DWZ6@1|root,342MS@2|Bacteria	595460.RRSWK_02302|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2878459_0	930171.Asphe3_09710	1.224e-282	871.0	COG2211@1|root,COG2211@2|Bacteria,2I3KV@201174|Actinobacteria,1W839@1268|Micrococcaceae	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_2878459_1	494419.ALPM01000035_gene3200	5.858e-44	162.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,1W8VV@1268|Micrococcaceae	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD2_k127_2882768_1	1449044.JMLE01000002_gene4468	6.637e-109	353.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,1W7KK@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD2_k127_2882768_4	1150398.JIBJ01000005_gene3252	3.523e-09	57.0	2BK86@1|root,32EN4@2|Bacteria,2GXC1@201174|Actinobacteria,1WACQ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2882877_1	1150398.JIBJ01000007_gene151	2.899e-57	200.0	COG1246@1|root,COG1246@2|Bacteria,2I5HV@201174|Actinobacteria	201174|Actinobacteria	E	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_2882877_0	290399.Arth_4034	2.213e-99	329.0	COG0406@1|root,COG0406@2|Bacteria,2GP71@201174|Actinobacteria,1W9ME@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	lpqD	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HKD2_k127_2882877_2	1312954.KI914852_gene638	3.541e-35	137.0	COG3568@1|root,COG3568@2|Bacteria,2H3ST@201174|Actinobacteria,1WB2R@1268|Micrococcaceae	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD2_k127_2884952_1	1449044.JMLE01000004_gene2579	1.278e-77	267.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,1W9N5@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	litS	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD2_k127_2884952_0	1158050.KB895452_gene687	3.074e-103	346.0	arCOG06227@1|root,2ZCRG@2|Bacteria,2I96P@201174|Actinobacteria,1W8K5@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD2_k127_2884952_3	1449044.JMLE01000011_gene3393	5.322e-33	128.0	2E46R@1|root,33FF6@2|Bacteria,2GS7S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2884952_2	930171.Asphe3_27560	8.441e-57	201.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,1W9HT@1268|Micrococcaceae	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HKD2_k127_2884952_4	1123065.ATWL01000002_gene1435	7.202e-23	98.0	2CH5R@1|root,32S5B@2|Bacteria,2IQUR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD2_k127_2891169_10	1150398.JIBJ01000011_gene2357	7.607e-88	294.0	COG3226@1|root,COG3226@2|Bacteria,2I3XB@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
HKD2_k127_2891169_9	290399.Arth_2808	1.469e-98	326.0	2DRTH@1|root,33CZB@2|Bacteria,2GY6H@201174|Actinobacteria,1WAGS@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2891169_8	1150398.JIBJ01000011_gene2355	2.296e-112	374.0	COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,1W8WH@1268|Micrococcaceae	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2891169_2	1077972.ARGLB_085_02280	1.248e-185	584.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,1W7RN@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
HKD2_k127_2891169_0	1449044.JMLE01000002_gene4248	7.522e-207	652.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,1W80Q@1268|Micrococcaceae	201174|Actinobacteria	E	Succinyl-diaminopimelate desuccinylase	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD2_k127_2891169_4	1101188.KI912155_gene661	3.18e-147	469.0	COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,1W83H@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	gluD	-	-	ko:K10007	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
HKD2_k127_2891169_11	288705.RSal33209_1182	2.745e-85	287.0	COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,1W83H@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	gluD	-	-	ko:K10007	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
HKD2_k127_2891169_3	1101188.KI912155_gene659	5.602e-156	509.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,1W7GR@1268|Micrococcaceae	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	gluB	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
HKD2_k127_2891169_5	290399.Arth_2801	1.029e-146	466.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,1W7V7@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter, ATP-binding protein	gluA	-	-	ko:K10008	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.9	-	-	ABC_tran
HKD2_k127_2891169_6	1150398.JIBJ01000011_gene2348	4.108e-145	466.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,1W86V@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD2_k127_2891169_12	1150398.JIBJ01000011_gene2347	2.621e-34	136.0	COG3599@1|root,COG3599@2|Bacteria,2I575@201174|Actinobacteria,1WAAG@1268|Micrococcaceae	201174|Actinobacteria	D	regulation of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
HKD2_k127_2891169_1	1150398.JIBJ01000011_gene2346	1.254e-202	639.0	COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria,1W8D4@1268|Micrococcaceae	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
HKD2_k127_2891169_13	1349820.M707_07275	1.499e-33	130.0	2E39N@1|root,32Y97@2|Bacteria,2GQFF@201174|Actinobacteria,1WA84@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3117
HKD2_k127_2891169_7	1150398.JIBJ01000011_gene2344	5.578e-122	397.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,1W964@1268|Micrococcaceae	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
HKD2_k127_2901917_2	1121106.JQKB01000116_gene5362	9.222e-36	137.0	COG1961@1|root,COG3039@1|root,COG1961@2|Bacteria,COG3039@2|Bacteria,1MXTN@1224|Proteobacteria,2TYT4@28211|Alphaproteobacteria,2JWYX@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_5
HKD2_k127_2901917_1	272134.KB731325_gene510	1.27e-43	162.0	COG2801@1|root,COG2801@2|Bacteria,1G5GD@1117|Cyanobacteria,1HGQD@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
HKD2_k127_2901917_3	329726.AM1_0495	2.536e-05	53.0	COG2801@1|root,COG2801@2|Bacteria,1G5GD@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
HKD2_k127_2901917_0	1123508.JH636439_gene1757	3.593e-143	463.0	COG3119@1|root,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
HKD2_k127_2910697_0	1150398.JIBJ01000015_gene2017	1.092e-132	426.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,1W7VX@1268|Micrococcaceae	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
HKD2_k127_2910697_1	1150398.JIBJ01000015_gene2016	8.648e-113	368.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,1W91N@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
HKD2_k127_2919785_1	290399.Arth_3583	7.766e-303	938.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,1W7Z7@1268|Micrococcaceae	201174|Actinobacteria	IQ	Activates fatty acids by binding to coenzyme A	fadD2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD2_k127_2919785_0	1150398.JIBJ01000004_gene2990	0.0	1412.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,1W7PV@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
HKD2_k127_2919785_2	290399.Arth_2032	7.628e-123	394.0	COG0009@1|root,COG0009@2|Bacteria,2GNEW@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
HKD2_k127_2919785_3	1151119.KB895498_gene3557	6.462e-78	263.0	COG3981@1|root,COG3981@2|Bacteria,2IGK9@201174|Actinobacteria	201174|Actinobacteria	L	Gcn5-related n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD2_k127_2919948_5	452863.Achl_3931	5.865e-41	154.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,1W7KC@1268|Micrococcaceae	201174|Actinobacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD2_k127_2919948_1	1151119.KB895493_gene1500	2.315e-118	384.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,1W92S@1268|Micrococcaceae	201174|Actinobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HKD2_k127_2919948_2	1150398.JIBJ01000007_gene236	1.035e-79	276.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,1W97Y@1268|Micrococcaceae	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
HKD2_k127_2919948_0	290399.Arth_4169	7.356e-178	560.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,1W8EF@1268|Micrococcaceae	201174|Actinobacteria	U	PFAM 60 kDa inner membrane insertion protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HKD2_k127_2919948_3	1077972.ARGLB_037_00480	8.49e-64	224.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,1W9QQ@1268|Micrococcaceae	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD2_k127_2919948_4	452863.Achl_3936	1.04e-57	203.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,1W9VW@1268|Micrococcaceae	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD2_k127_2919948_6	1077972.ARGLB_037_00500	3.844e-18	84.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD2_k127_2929835_2	1150398.JIBJ01000008_gene754	3.518e-21	93.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,1W82S@1268|Micrococcaceae	201174|Actinobacteria	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
HKD2_k127_2929835_0	1449044.JMLE01000010_gene3600	1.733e-283	874.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,1W7GH@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HKD2_k127_2929835_1	290399.Arth_3848	1.11e-134	435.0	COG0147@1|root,COG0572@1|root,COG0147@2|Bacteria,COG0572@2|Bacteria,2GKJT@201174|Actinobacteria,1W83E@1268|Micrococcaceae	201174|Actinobacteria	EH	synthase component I	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind,GATase
HKD2_k127_2933082_0	290399.Arth_4146	2.669e-245	767.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,1W85I@1268|Micrococcaceae	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	pbp2B	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	MecA_N,PBP_dimer,Transpeptidase
HKD2_k127_2959284_2	1150398.JIBJ01000008_gene804	1.428e-56	199.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,1W7SV@1268|Micrococcaceae	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HKD2_k127_2959284_1	290399.Arth_3887	5.654e-81	270.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,1W95Q@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HKD2_k127_2959284_0	1150398.JIBJ01000008_gene802	9.515e-166	524.0	COG0583@1|root,COG0583@2|Bacteria,2GM99@201174|Actinobacteria,1W8XJ@1268|Micrococcaceae	201174|Actinobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_2959284_3	452863.Achl_3674	6.531e-11	63.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,1W7V4@1268|Micrococcaceae	201174|Actinobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD2_k127_2960518_2	1206739.BAGJ01000176_gene3073	2.431e-15	76.0	COG2271@1|root,COG2271@2|Bacteria,2GIS1@201174|Actinobacteria,4FYA3@85025|Nocardiaceae	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_2960518_0	1158050.KB895465_gene3489	1.573e-117	385.0	COG4221@1|root,COG4221@2|Bacteria,2GRRV@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_2960518_1	1151118.KB895783_gene3724	5.109e-39	147.0	COG3795@1|root,COG3795@2|Bacteria,2IKXM@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD2_k127_2963833_1	1077972.ARGLB_037_00600	5.807e-88	294.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,1W9HN@1268|Micrococcaceae	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
HKD2_k127_2963833_0	1150398.JIBJ01000007_gene245	1.67e-311	958.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,1W7NR@1268|Micrococcaceae	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD2_k127_2990711_3	1151119.KB895500_gene2726	1.758e-105	346.0	COG2186@1|root,COG2186@2|Bacteria,2GKBM@201174|Actinobacteria,1W9MP@1268|Micrococcaceae	201174|Actinobacteria	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HKD2_k127_2990711_0	1151119.KB895500_gene2725	7.693e-230	718.0	COG1653@1|root,COG1653@2|Bacteria,2GNI2@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
HKD2_k127_2990711_1	1151119.KB895500_gene2724	9.846e-169	533.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HKD2_k127_2990711_2	1151119.KB895500_gene2723	1.153e-150	497.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria,1WCBH@1268|Micrococcaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HKD2_k127_2997853_1	290399.Arth_2489	1.642e-179	567.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,1W7ST@1268|Micrococcaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD2_k127_2997853_0	290399.Arth_2490	1.769e-185	582.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,1W8FU@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
HKD2_k127_2998636_3	1394178.AWOO02000060_gene507	6.757e-11	65.0	COG3415@1|root,COG3415@2|Bacteria,2IHIM@201174|Actinobacteria,4EQ0E@85012|Streptosporangiales	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_29,HTH_32,HTH_33
HKD2_k127_2998636_1	591167.Sfla_6450	9.043e-57	207.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
HKD2_k127_2998636_2	1169154.KB897781_gene5441	1.103e-55	201.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_2998636_0	263358.VAB18032_01470	2.189e-78	273.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4DC2W@85008|Micromonosporales	201174|Actinobacteria	L	FOG Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
HKD2_k127_3008968_0	1150398.JIBJ01000002_gene1016	6.263e-260	803.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,1W8F1@1268|Micrococcaceae	201174|Actinobacteria	E	TIGRFAM formaldehyde dehydrogenase, glutathione-independent	fdhA	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,AlaDh_PNT_C
HKD2_k127_3008968_1	290399.Arth_0561	8.976e-49	177.0	COG1409@1|root,COG1409@2|Bacteria,2HKQQ@201174|Actinobacteria,1WB44@1268|Micrococcaceae	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD2_k127_3015093_1	385682.AFSL01000040_gene227	1.206e-14	86.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	2.7.7.4	ko:K00957,ko:K07497	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_23,HTH_29,PAPS_reduct,rve,rve_3
HKD2_k127_3015093_0	886293.Sinac_3713	2.567e-115	377.0	COG4948@1|root,COG4948@2|Bacteria,2IX8Q@203682|Planctomycetes	2|Bacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
HKD2_k127_3017707_0	1299327.I546_3206	2.91e-88	298.0	COG1028@1|root,COG1028@2|Bacteria,2I3EJ@201174|Actinobacteria,237YX@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_3017707_1	1463917.JODC01000044_gene2166	5.271e-88	310.0	COG1028@1|root,COG1028@2|Bacteria,2IAN1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HKD2_k127_3017707_4	656024.FsymDg_4147	4.335e-20	96.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
HKD2_k127_3017707_2	326424.FRAAL4653	3.501e-62	217.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
HKD2_k127_3017707_3	1120948.KB903229_gene5070	1.608e-48	175.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4DZVF@85010|Pseudonocardiales	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD2_k127_3068672_0	1150398.JIBJ01000009_gene421	5e-324	994.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,1W7Y0@1268|Micrococcaceae	201174|Actinobacteria	L	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
HKD2_k127_3068672_2	1150398.JIBJ01000009_gene422	1.565e-144	461.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,1W8BQ@1268|Micrococcaceae	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HKD2_k127_3068672_3	1150398.JIBJ01000009_gene423	2.926e-41	158.0	COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria,1WA5I@1268|Micrococcaceae	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD2_k127_3068672_1	930171.Asphe3_14530	2.087e-214	668.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,1W82X@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_3068672_4	290399.Arth_1471	7.516e-22	96.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,1W8FB@1268|Micrococcaceae	201174|Actinobacteria	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HKD2_k127_3072435_3	1449044.JMLE01000003_gene2959	1.65e-67	231.0	COG0025@1|root,COG5207@1|root,COG0025@2|Bacteria,COG5207@2|Bacteria,2GIUT@201174|Actinobacteria,1W86C@1268|Micrococcaceae	201174|Actinobacteria	P	Na H antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
HKD2_k127_3072435_0	290399.Arth_3530	8.722e-229	715.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,1W88D@1268|Micrococcaceae	201174|Actinobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HKD2_k127_3072435_2	1132441.KI519455_gene3825	4.802e-103	348.0	COG2801@1|root,COG2801@2|Bacteria,2IEHA@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
HKD2_k127_3072435_4	1132441.KI519455_gene3824	3.519e-36	143.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
HKD2_k127_3072435_1	494419.ALPM01000044_gene2529	3.642e-182	572.0	COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
HKD2_k127_3074523_1	1121362.A605_00275	4.001e-37	141.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,22PAI@1653|Corynebacteriaceae	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
HKD2_k127_3074523_3	1151119.KB895496_gene3850	1.59e-23	102.0	2BMBM@1|root,32FVR@2|Bacteria,2HCE3@201174|Actinobacteria,1WC69@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3074523_0	930171.Asphe3_36440	4.373e-59	213.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3074523_2	290399.Arth_3457	1.414e-28	115.0	COG0589@1|root,COG0589@2|Bacteria,2HESA@201174|Actinobacteria,1WBX0@1268|Micrococcaceae	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD2_k127_3085688_3	1150398.JIBJ01000004_gene3000	8.75e-67	245.0	2ERCX@1|root,33IYJ@2|Bacteria,2IJT0@201174|Actinobacteria,1W9GJ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3085688_2	1150398.JIBJ01000004_gene2999	3.484e-143	464.0	COG0589@1|root,COG0589@2|Bacteria,2GQ37@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD2_k127_3085688_1	1150398.JIBJ01000004_gene2998	2.501e-246	779.0	COG2312@1|root,COG2312@2|Bacteria,2I2XA@201174|Actinobacteria	201174|Actinobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
HKD2_k127_3085688_0	1150398.JIBJ01000004_gene2997	8.12e-255	791.0	COG1236@1|root,COG1236@2|Bacteria,2HEXB@201174|Actinobacteria,1WAYE@1268|Micrococcaceae	201174|Actinobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
HKD2_k127_3114827_7	1349820.M707_17730	2.202e-19	87.0	COG1054@1|root,COG1054@2|Bacteria,2GMMP@201174|Actinobacteria,1W8JF@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
HKD2_k127_3114827_2	1150398.JIBJ01000002_gene1121	2.883e-136	440.0	COG4307@1|root,COG4307@2|Bacteria,2GKD6@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
HKD2_k127_3114827_0	452863.Achl_1807	7.615e-178	567.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD2_k127_3114827_1	1077972.ARGLB_080_00230	8.061e-167	527.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,1W7S6@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD2_k127_3114827_3	1150398.JIBJ01000024_gene3916	1.338e-102	343.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,1W9HE@1268|Micrococcaceae	201174|Actinobacteria	K	TipAS antibiotic-recognition domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
HKD2_k127_3114827_4	1150398.JIBJ01000024_gene3915	6.118e-82	276.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,1W7R3@1268|Micrococcaceae	201174|Actinobacteria	J	Methyltransferase small domain	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
HKD2_k127_3128009_3	290399.Arth_2878	4.028e-61	221.0	COG3103@1|root,COG3103@2|Bacteria,2IGZN@201174|Actinobacteria,1WA9S@1268|Micrococcaceae	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF4157,Phenol_MetA_deg,SH3_3
HKD2_k127_3128009_2	1150398.JIBJ01000015_gene1963	2.41e-160	507.0	COG1073@1|root,COG1073@2|Bacteria,2I5TW@201174|Actinobacteria,1W8CZ@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HKD2_k127_3128009_4	288705.RSal33209_1510	3.024e-47	173.0	COG0508@1|root,COG0508@2|Bacteria,2INGT@201174|Actinobacteria,1WBJB@1268|Micrococcaceae	201174|Actinobacteria	C	Biotin-requiring enzyme	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
HKD2_k127_3128009_0	1150398.JIBJ01000015_gene1961	7.505e-203	637.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,1W8EH@1268|Micrococcaceae	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD2_k127_3128009_1	1150398.JIBJ01000015_gene1960	6.086e-197	617.0	COG1071@1|root,COG1071@2|Bacteria,2HZWG@201174|Actinobacteria,1W7N7@1268|Micrococcaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD2_k127_3128009_5	1150398.JIBJ01000015_gene1959	3.05e-15	76.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,1W7WF@1268|Micrococcaceae	201174|Actinobacteria	E	amino acid	aroP	-	-	ko:K03293,ko:K11735,ko:K16237	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.12,2.A.3.1.4,2.A.3.1.5	-	-	AA_permease
HKD2_k127_3155003_1	1120917.AQXM01000050_gene1011	2.189e-70	238.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,1W7FS@1268|Micrococcaceae	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD2_k127_3155003_2	290340.AAur_1762	9.372e-36	138.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,1WA2V@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3155003_0	1150398.JIBJ01000003_gene1927	3.948e-161	513.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,1W8GY@1268|Micrococcaceae	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD2_k127_3158871_1	1150398.JIBJ01000002_gene1154	1.026e-141	453.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,1W7WA@1268|Micrococcaceae	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD2_k127_3158871_2	1150398.JIBJ01000002_gene1155	5.09e-97	323.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FHA,NAD_binding_8,Pyr_redox_2
HKD2_k127_3158871_3	290399.Arth_0381	1.568e-65	230.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,1W9NQ@1268|Micrococcaceae	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K07156,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC,CopD
HKD2_k127_3158871_0	1150398.JIBJ01000002_gene1157	8.363e-294	904.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,1W82D@1268|Micrococcaceae	201174|Actinobacteria	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HKD2_k127_3158871_4	1150398.JIBJ01000002_gene1158	2.823e-26	110.0	COG0010@1|root,COG0010@2|Bacteria,2IA0Q@201174|Actinobacteria,1W89T@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD2_k127_3171634_4	1150398.JIBJ01000010_gene486	1.103e-55	196.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,1W8AT@1268|Micrococcaceae	201174|Actinobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HKD2_k127_3171634_3	290399.Arth_2766	1.971e-115	384.0	COG1587@1|root,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,1W9C7@1268|Micrococcaceae	201174|Actinobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD2_k127_3171634_1	1150398.JIBJ01000010_gene484	1.509e-185	584.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,1W8GX@1268|Micrococcaceae	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
HKD2_k127_3171634_0	1150398.JIBJ01000010_gene483	7.632e-252	789.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,1W7W4@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
HKD2_k127_3171634_2	290399.Arth_2769	2.218e-140	447.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,1W8FW@1268|Micrococcaceae	201174|Actinobacteria	S	chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
HKD2_k127_3171634_5	1150398.JIBJ01000010_gene480	8.584e-28	113.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,1W7TH@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
HKD2_k127_317167_3	1150398.JIBJ01000008_gene823	2.195e-182	577.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,1W8JZ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HKD2_k127_317167_2	1449044.JMLE01000010_gene3649	6.337e-185	582.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,1W89F@1268|Micrococcaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	yvbT	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_317167_4	1151119.KB895494_gene3139	2.351e-161	516.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,1WCI4@1268|Micrococcaceae	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
HKD2_k127_317167_6	290399.Arth_3900	1.091e-120	391.0	COG0693@1|root,COG0693@2|Bacteria,2GMFW@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM ThiJ PfpI domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
HKD2_k127_317167_1	1449044.JMLE01000010_gene3666	4.918e-305	941.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,1W7YQ@1268|Micrococcaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
HKD2_k127_317167_5	1150398.JIBJ01000008_gene829	5.325e-160	511.0	COG3087@1|root,COG3087@2|Bacteria,2IEWB@201174|Actinobacteria,1W7RH@1268|Micrococcaceae	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_317167_0	1150398.JIBJ01000008_gene830	0.0	1236.0	COG0526@1|root,COG0526@2|Bacteria,2GKDT@201174|Actinobacteria,1W88Z@1268|Micrococcaceae	201174|Actinobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,NHL,Thioredoxin_8
HKD2_k127_317167_7	1449044.JMLE01000010_gene3670	1.185e-11	64.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,1W8D7@1268|Micrococcaceae	201174|Actinobacteria	P	Copper resistance	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
HKD2_k127_3188487_1	1150398.JIBJ01000019_gene857	4.505e-123	398.0	COG0583@1|root,COG0583@2|Bacteria,2GNFT@201174|Actinobacteria,1W8T4@1268|Micrococcaceae	201174|Actinobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_3188487_0	1304876.AZVC01000001_gene1751	1.731e-162	512.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,1W886@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HKD2_k127_3208635_1	290399.Arth_2163	3.473e-93	309.0	COG1960@1|root,COG1960@2|Bacteria,2HSST@201174|Actinobacteria,1W7MD@1268|Micrococcaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_3208635_0	1449044.JMLE01000001_gene4014	1.907e-274	845.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,1W7IP@1268|Micrococcaceae	201174|Actinobacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD2_k127_3212450_3	1150398.JIBJ01000010_gene592	8.982e-88	305.0	COG1695@1|root,COG1695@2|Bacteria,2GMKD@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD2_k127_3212450_1	1150398.JIBJ01000010_gene593	3.42e-150	479.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HKD2_k127_3212450_2	1158050.KB895452_gene182	3.232e-122	394.0	COG2755@1|root,COG2755@2|Bacteria,2IA8J@201174|Actinobacteria,1W92B@1268|Micrococcaceae	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_3212450_0	290399.Arth_2645	1.489e-252	781.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,1W8AB@1268|Micrococcaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HKD2_k127_3248997_1	1449044.JMLE01000022_gene1473	6.603e-73	248.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria,1W9HH@1268|Micrococcaceae	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD2_k127_3248997_0	1150398.JIBJ01000023_gene3878	3.514e-242	750.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,1W7RR@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_3255077_1	290399.Arth_1380	6.652e-86	286.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria,1W9HK@1268|Micrococcaceae	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD2_k127_3255077_0	1150398.JIBJ01000009_gene334	5.344e-220	687.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,1W89B@1268|Micrococcaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD2_k127_3264302_0	1157943.KB892705_gene703	3.723e-203	646.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria,237RJ@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
HKD2_k127_3264302_1	1299327.I546_4389	6.897e-41	155.0	COG1321@1|root,COG1321@2|Bacteria,2ICG2@201174|Actinobacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
HKD2_k127_3266663_1	1150398.JIBJ01000007_gene185	1.003e-48	181.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,1W9PZ@1268|Micrococcaceae	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HKD2_k127_3266663_0	1077972.ARGLB_036_00130	5.067e-224	699.0	COG3292@1|root,COG3292@2|Bacteria,2I5U5@201174|Actinobacteria	201174|Actinobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3266663_2	1077972.ARGLB_036_00140	1.911e-35	136.0	COG1977@1|root,COG1977@2|Bacteria,2GQM9@201174|Actinobacteria	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD2_k127_3268528_6	1150398.JIBJ01000008_gene759	1.444e-28	126.0	COG1649@1|root,COG1649@2|Bacteria,2GXT3@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3268528_0	1150398.JIBJ01000008_gene760	2.795e-213	672.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,1WBCF@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Polysacc_deac_1
HKD2_k127_3268528_3	1349820.M707_06210	3.496e-74	260.0	COG0189@1|root,COG0189@2|Bacteria,2IK92@201174|Actinobacteria	201174|Actinobacteria	HJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
HKD2_k127_3268528_1	1150398.JIBJ01000008_gene762	3.423e-160	510.0	COG2120@1|root,COG2120@2|Bacteria,2GMXC@201174|Actinobacteria	201174|Actinobacteria	T	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD2_k127_3268528_4	290399.Arth_3858	1.067e-48	178.0	COG5515@1|root,COG5515@2|Bacteria,2GUHP@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1737)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1737
HKD2_k127_3268528_5	290399.Arth_3859	3.186e-48	181.0	COG0607@1|root,COG0607@2|Bacteria,2IN3Q@201174|Actinobacteria,1W9J8@1268|Micrococcaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_3268528_2	1349820.M707_19035	4.415e-151	480.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,1W8HN@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0391	Cys_Met_Meta_PP
HKD2_k127_3287489_0	1150398.JIBJ01000009_gene339	3.615e-314	974.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,1W8EI@1268|Micrococcaceae	201174|Actinobacteria	I	Biotin carboxylase	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
HKD2_k127_3304331_3	1150398.JIBJ01000002_gene1275	2.42e-38	143.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,1W9QG@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
HKD2_k127_3304331_0	1150398.JIBJ01000002_gene1276	1.297e-158	503.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,1W7GZ@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD2_k127_3304331_1	1449044.JMLE01000006_gene1064	4.717e-121	390.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,1W897@1268|Micrococcaceae	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
HKD2_k127_3304331_2	1150398.JIBJ01000002_gene1278	1.966e-61	213.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,1W8A6@1268|Micrococcaceae	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD2_k127_3305300_0	595460.RRSWK_01451	1.508e-32	132.0	2DWZ6@1|root,342MS@2|Bacteria	595460.RRSWK_01451|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3305300_1	688246.Premu_2107	2.132e-21	106.0	2946W@1|root,2ZRMA@2|Bacteria	2|Bacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3310945_2	1463858.JOHR01000003_gene1924	2.398e-33	143.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria	201174|Actinobacteria	IQ	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
HKD2_k127_3310945_0	1150399.AQYK01000001_gene952	1.535e-173	554.0	COG0477@1|root,COG0477@2|Bacteria,2I2Q2@201174|Actinobacteria,4FRAB@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
HKD2_k127_3310945_1	1380354.JIAN01000005_gene2314	1.574e-148	475.0	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
HKD2_k127_3321116_3	930171.Asphe3_29110	3.428e-60	209.0	COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,1WCHY@1268|Micrococcaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_3321116_0	290399.Arth_3078	6.165e-304	943.0	COG0753@1|root,COG0753@2|Bacteria,2GITN@201174|Actinobacteria,1W7QZ@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the catalase family	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
HKD2_k127_3321116_2	290399.Arth_3077	3.838e-84	281.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,1W9HV@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the Fur family	catR	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD2_k127_3321116_1	1449044.JMLE01000002_gene4524	1.829e-226	706.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,1W7N5@1268|Micrococcaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
HKD2_k127_3331554_2	1158050.KB895461_gene2980	8.3e-18	91.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	yknZ	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
HKD2_k127_3331554_0	1158050.KB895461_gene2979	1.42e-120	390.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,1W7J8@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_3331554_1	1158050.KB895461_gene2978	1.888e-77	265.0	COG0845@1|root,COG0845@2|Bacteria,2H154@201174|Actinobacteria	201174|Actinobacteria	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD2_k127_3335180_4	1150398.JIBJ01000019_gene844	5.177e-35	135.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,1W8EV@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
HKD2_k127_3335180_2	452863.Achl_2264	2.583e-157	507.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,1W81A@1268|Micrococcaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF2437)	fahA	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
HKD2_k127_3335180_3	1150398.JIBJ01000019_gene846	9.988e-123	402.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,1W80Y@1268|Micrococcaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_3335180_0	1150398.JIBJ01000019_gene847	8.529e-230	714.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,1W7I8@1268|Micrococcaceae	201174|Actinobacteria	E	Aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD2_k127_3335180_1	1150398.JIBJ01000019_gene848	1.811e-170	537.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,1W87R@1268|Micrococcaceae	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD2_k127_3454418_3	1449044.JMLE01000001_gene4097	8.779e-17	79.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,1W7JT@1268|Micrococcaceae	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
HKD2_k127_3454418_0	1150398.JIBJ01000004_gene3026	2.982e-196	613.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,1W8GI@1268|Micrococcaceae	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
HKD2_k127_3454418_1	290399.Arth_2086	1.413e-133	426.0	COG0605@1|root,COG0605@2|Bacteria,2GJV8@201174|Actinobacteria,1W8BW@1268|Micrococcaceae	201174|Actinobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD2_k127_3454418_2	1150398.JIBJ01000004_gene3028	5.099e-63	217.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,1W7Q3@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD2_k127_346272_1	1158050.KB895455_gene1709	3.186e-175	552.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,1W7F0@1268|Micrococcaceae	201174|Actinobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
HKD2_k127_346272_3	930171.Asphe3_10460	4.05e-88	295.0	COG1853@1|root,COG1853@2|Bacteria,2GK9V@201174|Actinobacteria,1W9MJ@1268|Micrococcaceae	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD2_k127_346272_2	1150398.JIBJ01000002_gene1168	7.072e-141	450.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,1W7Z1@1268|Micrococcaceae	201174|Actinobacteria	IQ	3-hydroxybutyrate dehydrogenase	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD2_k127_346272_0	290399.Arth_0365	1.261e-270	835.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1W8NJ@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_346272_5	290399.Arth_0364	2.822e-32	128.0	COG0583@1|root,COG0583@2|Bacteria,2GMWK@201174|Actinobacteria,1W98U@1268|Micrococcaceae	201174|Actinobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_3470220_8	1449044.JMLE01000007_gene1172	4.76e-10	63.0	COG4478@1|root,COG4478@2|Bacteria,2IFW4@201174|Actinobacteria,1W8XP@1268|Micrococcaceae	201174|Actinobacteria	D	TIGRFAM integral membrane protein TIGR01906	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
HKD2_k127_3470220_3	1449044.JMLE01000007_gene1175	2.489e-192	611.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,1W867@1268|Micrococcaceae	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	lppS	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD2_k127_3470220_2	1449044.JMLE01000007_gene1176	1.476e-204	648.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,1W867@1268|Micrococcaceae	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	lppS	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD2_k127_3470220_0	452863.Achl_1269	1.017e-309	951.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,1W7GS@1268|Micrococcaceae	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
HKD2_k127_3470220_7	1150398.JIBJ01000006_gene3560	6.425e-26	109.0	COG2835@1|root,COG2835@2|Bacteria,2HDNM@201174|Actinobacteria,1WACF@1268|Micrococcaceae	201174|Actinobacteria	S	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_3470220_6	290399.Arth_1196	1.23e-60	213.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,1WA16@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
HKD2_k127_3470220_5	1150398.JIBJ01000006_gene3562	1.219e-80	271.0	COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria,1WBNB@1268|Micrococcaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
HKD2_k127_3470220_1	1449044.JMLE01000007_gene1181	2.295e-208	664.0	COG3147@1|root,COG3147@2|Bacteria,2HC8A@201174|Actinobacteria,1W8W7@1268|Micrococcaceae	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3470220_4	1150398.JIBJ01000006_gene3564	2.313e-130	425.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,1W7U4@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
HKD2_k127_3487300_1	522306.CAP2UW1_1998	9.14e-35	136.0	29VND@1|root,30H5P@2|Bacteria,1RBVN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3487300_0	1123274.KB899408_gene3794	1.477e-86	299.0	COG1457@1|root,COG1457@2|Bacteria,2J6MY@203691|Spirochaetes	203691|Spirochaetes	F	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
HKD2_k127_3500446_3	1150398.JIBJ01000002_gene935	7.761e-16	78.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,1WB9X@1268|Micrococcaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_3500446_0	1150398.JIBJ01000002_gene934	6.891e-156	494.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,1W94Z@1268|Micrococcaceae	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HKD2_k127_3500446_2	408672.NBCG_01508	8.473e-24	103.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4DPDX@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
HKD2_k127_3500446_1	1150398.JIBJ01000002_gene933	4.788e-55	193.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,1W837@1268|Micrococcaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
HKD2_k127_352724_0	1150398.JIBJ01000003_gene1845	1.082e-152	484.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,1W7TZ@1268|Micrococcaceae	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
HKD2_k127_352724_1	1150398.JIBJ01000003_gene1846	1.356e-134	437.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,1W89R@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HKD2_k127_352724_3	1150398.JIBJ01000003_gene1847	6.687e-38	147.0	290XR@1|root,2ZNJH@2|Bacteria,2GV1T@201174|Actinobacteria,1WA2N@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_352724_2	1150398.JIBJ01000003_gene1848	1.694e-80	273.0	2EGC7@1|root,33A40@2|Bacteria,2HTAP@201174|Actinobacteria,1WA4G@1268|Micrococcaceae	201174|Actinobacteria	S	Tryptophan-associated transmembrane protein (Trp_oprn_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_oprn_chp
HKD2_k127_3551582_0	1150398.JIBJ01000013_gene2511	0.0	1203.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,1W7HX@1268|Micrococcaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
HKD2_k127_3556085_3	1150398.JIBJ01000023_gene3871	4.056e-18	83.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,1W9E7@1268|Micrococcaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
HKD2_k127_3556085_2	290399.Arth_0872	3.617e-75	254.0	COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria	201174|Actinobacteria	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
HKD2_k127_3556085_4	1077972.ARGLB_064_00690	5.226e-06	55.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PAS_3
HKD2_k127_3556085_0	1150398.JIBJ01000023_gene3874	4.049e-219	685.0	COG4268@1|root,COG4268@2|Bacteria,2GKET@201174|Actinobacteria,1W9TJ@1268|Micrococcaceae	201174|Actinobacteria	V	McrBC 5-methylcytosine restriction system component	-	-	-	ko:K19147	-	-	-	-	ko00000,ko02048	-	-	-	McrBC
HKD2_k127_3556085_1	1449044.JMLE01000022_gene1476	1.483e-134	429.0	COG0464@1|root,COG1401@1|root,COG0464@2|Bacteria,COG1401@2|Bacteria,2GM1I@201174|Actinobacteria,1W9XC@1268|Micrococcaceae	201174|Actinobacteria	L	AAA domain (dynein-related subfamily)	mcrB	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
HKD2_k127_3567578_2	1150398.JIBJ01000004_gene2798	1.18e-90	304.0	COG3021@1|root,COG3021@2|Bacteria,2IABR@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD2_k127_3567578_0	1150398.JIBJ01000004_gene2799	1.947e-158	503.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,1W8ZK@1268|Micrococcaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
HKD2_k127_3567578_3	290399.Arth_2326	3.413e-59	207.0	COG4852@1|root,COG4852@2|Bacteria,2GQ8R@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
HKD2_k127_3567578_1	1150398.JIBJ01000004_gene2801	4.954e-98	324.0	COG0095@1|root,COG0095@2|Bacteria,2IG61@201174|Actinobacteria,1W947@1268|Micrococcaceae	201174|Actinobacteria	H	Lipoate-protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3621087_0	1150398.JIBJ01000007_gene173	1.955e-203	644.0	COG1082@1|root,COG3185@1|root,COG1082@2|Bacteria,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria,1W7S5@1268|Micrococcaceae	201174|Actinobacteria	EG	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AP_endonuc_2,Glyoxalase,Glyoxalase_5
HKD2_k127_3621087_1	1449044.JMLE01000014_gene2308	3.577e-136	436.0	COG0169@1|root,COG0169@2|Bacteria,2GPXV@201174|Actinobacteria,1W7Q2@1268|Micrococcaceae	201174|Actinobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_dh_N,ThiF
HKD2_k127_364364_3	1150398.JIBJ01000007_gene248	3.611e-59	206.0	COG0697@1|root,COG0697@2|Bacteria,2I198@201174|Actinobacteria,1WBRV@1268|Micrococcaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_364364_0	290399.Arth_0010	3.937e-166	527.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,1W8IM@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_364364_1	1449044.JMLE01000019_gene1781	1.287e-133	433.0	2DD1M@1|root,2ZG5Q@2|Bacteria,2IFGU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_364364_2	1150398.JIBJ01000007_gene251	1.119e-114	372.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,1W90A@1268|Micrococcaceae	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HKD2_k127_364364_4	290340.AAur_0017	2.229e-26	108.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,1W97V@1268|Micrococcaceae	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
HKD2_k127_3646205_3	1449044.JMLE01000001_gene3985	4.335e-110	363.0	COG0500@1|root,COG2226@2|Bacteria,2HCAN@201174|Actinobacteria,1W9KF@1268|Micrococcaceae	201174|Actinobacteria	Q	Methyltransferase domain	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
HKD2_k127_3646205_5	1349820.M707_00730	2.857e-60	224.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria,1W9SI@1268|Micrococcaceae	201174|Actinobacteria	OU	NfeD-like C-terminal, partner-binding	nfeD	-	-	-	-	-	-	-	-	-	-	-	NfeD
HKD2_k127_3646205_1	290399.Arth_2189	2.012e-167	530.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,1W7U0@1268|Micrococcaceae	201174|Actinobacteria	O	prohibitin homologues	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
HKD2_k127_3646205_4	290399.Arth_2188	1.485e-65	225.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,1W9F0@1268|Micrococcaceae	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
HKD2_k127_3646205_2	1150398.JIBJ01000013_gene2509	1.825e-145	464.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,1W8CU@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD2_k127_3646205_0	290399.Arth_2186	6.406e-220	688.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,1W8DT@1268|Micrococcaceae	201174|Actinobacteria	S	Amidohydrolase family	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD2_k127_368392_5	1471459.JFLJ01000087_gene1278	0.0001028	45.0	2B9CK@1|root,322QB@2|Bacteria,1GNDI@1117|Cyanobacteria,1MP8T@1212|Prochloraceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_368392_1	1449044.JMLE01000020_gene1842	1.065e-250	778.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,1W7I7@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD2_k127_368392_0	290399.Arth_1511	0.0	1321.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,1W8J8@1268|Micrococcaceae	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
HKD2_k127_368392_4	1150398.JIBJ01000009_gene469	2.601e-82	278.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,1W8XB@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HKD2_k127_368392_3	1158050.KB895468_gene3204	6.517e-105	345.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,1W99W@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	alkA	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD2_k127_368392_2	1150398.JIBJ01000009_gene465	4.782e-198	623.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,1W842@1268|Micrococcaceae	201174|Actinobacteria	FL	AlkA N-terminal domain	alkA	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
HKD2_k127_3684199_0	1150398.JIBJ01000013_gene2512	4.477e-125	402.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,1W7NG@1268|Micrococcaceae	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD2_k127_3684199_1	1150398.JIBJ01000013_gene2513	1.806e-36	139.0	COG1826@1|root,COG1826@2|Bacteria,2HTA4@201174|Actinobacteria,1WA1J@1268|Micrococcaceae	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HKD2_k127_3684199_2	1077972.ARGLB_058_00340	4.969e-32	131.0	2AYXA@1|root,31R30@2|Bacteria,2GS8V@201174|Actinobacteria,1WA7P@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3684199_3	1158050.KB895454_gene1376	1.055e-12	69.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,1W8EM@1268|Micrococcaceae	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
HKD2_k127_3686393_1	930171.Asphe3_31480	2.696e-114	374.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,1W7J0@1268|Micrococcaceae	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
HKD2_k127_3686393_0	1150398.JIBJ01000002_gene1316	1.768e-146	468.0	COG1073@1|root,COG1073@2|Bacteria,2I5TQ@201174|Actinobacteria,1W9AQ@1268|Micrococcaceae	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HKD2_k127_3686393_2	1449044.JMLE01000006_gene1006	1.592e-104	345.0	COG2357@1|root,COG2357@2|Bacteria,2GKF8@201174|Actinobacteria,1W8UI@1268|Micrococcaceae	201174|Actinobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,RelA_SpoT
HKD2_k127_3697875_1	290340.AAur_1480	1.51e-55	198.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,1W8Z2@1268|Micrococcaceae	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
HKD2_k127_3697875_0	1150398.JIBJ01000006_gene3460	5.193e-167	529.0	COG2755@1|root,COG2755@2|Bacteria,2GNBP@201174|Actinobacteria,1W7H2@1268|Micrococcaceae	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_3718618_3	290399.Arth_2711	2.288e-73	253.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria,1W7II@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_3718618_1	1449044.JMLE01000005_gene718	2.879e-138	440.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,1W88X@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_3718618_2	1150398.JIBJ01000010_gene530	2.097e-122	397.0	arCOG11972@1|root,30KBF@2|Bacteria,2I5TX@201174|Actinobacteria,1W9KP@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
HKD2_k127_3718618_0	1150398.JIBJ01000010_gene529	6.378e-155	496.0	COG0620@1|root,COG0620@2|Bacteria,2GMPS@201174|Actinobacteria,1W9I4@1268|Micrococcaceae	201174|Actinobacteria	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
HKD2_k127_373992_0	1150398.JIBJ01000002_gene893	9.478e-152	481.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,1W7EV@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	tcrX	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_3783657_2	1150398.JIBJ01000005_gene3229	2.275e-11	64.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,1W834@1268|Micrococcaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_3783657_0	1077972.ARGLB_080_01700	3.895e-263	826.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,1WAT8@1268|Micrococcaceae	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD2_k127_3783657_1	1150398.JIBJ01000005_gene3231	1.51e-103	336.0	COG0754@1|root,COG0754@2|Bacteria,2GMQ5@201174|Actinobacteria,1W7QW@1268|Micrococcaceae	201174|Actinobacteria	E	Glutathionylspermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
HKD2_k127_3834050_1	1449044.JMLE01000010_gene3547	8.729e-142	452.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,1W7EZ@1268|Micrococcaceae	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD2_k127_3834050_2	1150398.JIBJ01000008_gene727	1.53e-113	368.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,1W8ZW@1268|Micrococcaceae	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HKD2_k127_3834050_0	1077972.ARGLB_073_01110	2.883e-186	584.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,1W8NZ@1268|Micrococcaceae	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD2_k127_3834052_4	1150398.JIBJ01000002_gene1198	5.683e-85	285.0	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria,1WCEB@1268|Micrococcaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
HKD2_k127_3834052_1	290399.Arth_0306	1.193e-164	529.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,1W90Y@1268|Micrococcaceae	201174|Actinobacteria	K	lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
HKD2_k127_3834052_3	290399.Arth_0305	5.292e-113	366.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,1W920@1268|Micrococcaceae	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
HKD2_k127_3834052_6	1150398.JIBJ01000002_gene1201	1.578e-38	147.0	2DRBI@1|root,33B4D@2|Bacteria,2GWXK@201174|Actinobacteria,1WC4C@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3834052_2	1150398.JIBJ01000002_gene1202	2.292e-123	401.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria,1W8HJ@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator, DeoR family	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HKD2_k127_3834052_0	1150398.JIBJ01000002_gene1203	2.207e-173	551.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,1W7SN@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.11,2.7.1.56	ko:K00882,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R02071,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HKD2_k127_3834052_5	1150398.JIBJ01000002_gene1204	6.922e-80	270.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,1W7N3@1268|Micrococcaceae	201174|Actinobacteria	GT	PTS system, fructose-specific	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HKD2_k127_3839774_2	290399.Arth_1588	8.41e-89	293.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,1W7Q6@1268|Micrococcaceae	201174|Actinobacteria	GK	Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD2_k127_3839774_1	290399.Arth_1586	1.489e-89	297.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,1W97H@1268|Micrococcaceae	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HKD2_k127_3839774_0	1150398.JIBJ01000014_gene2453	1.427e-228	715.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,1W7ZS@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
HKD2_k127_3839774_3	1151118.KB895794_gene1756	8.64e-55	218.0	COG1853@1|root,COG1853@2|Bacteria,2GYGX@201174|Actinobacteria	201174|Actinobacteria	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD2_k127_3839842_2	290399.Arth_0736	5.116e-211	660.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,1W8A2@1268|Micrococcaceae	201174|Actinobacteria	G	Protein of unknown function (DUF3417)	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
HKD2_k127_3839842_0	1150398.JIBJ01000001_gene1355	0.0	1292.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,1W87G@1268|Micrococcaceae	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
HKD2_k127_3839842_1	1449044.JMLE01000011_gene3366	2.439e-226	702.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,1W86G@1268|Micrococcaceae	201174|Actinobacteria	G	Trehalose synthase	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
HKD2_k127_3840371_1	930171.Asphe3_20930	3.702e-21	93.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,1W8QY@1268|Micrococcaceae	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_3840371_0	1150398.JIBJ01000002_gene1174	0.0	1444.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,1W82E@1268|Micrococcaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
HKD2_k127_3847072_0	1449044.JMLE01000013_gene2683	3.318e-96	322.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD2_k127_3847072_2	1150398.JIBJ01000018_gene2231	6.004e-34	132.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,1WBU8@1268|Micrococcaceae	201174|Actinobacteria	K	Cold shock protein domain	scoF4	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_3847072_1	1449044.JMLE01000013_gene2685	7.928e-50	183.0	2DP6P@1|root,330SA@2|Bacteria,2IIAP@201174|Actinobacteria,1W9GA@1268|Micrococcaceae	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
HKD2_k127_3859356_3	452863.Achl_2719	6.351e-36	139.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,1W7NK@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
HKD2_k127_3859356_0	290399.Arth_3009	1.752e-145	467.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria	201174|Actinobacteria	S	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD2_k127_3859356_1	1150398.JIBJ01000005_gene3261	2.116e-123	397.0	COG3485@1|root,COG3485@2|Bacteria,2I2IN@201174|Actinobacteria,1W8RZ@1268|Micrococcaceae	201174|Actinobacteria	Q	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
HKD2_k127_3859356_2	1150398.JIBJ01000005_gene3259	3.514e-119	388.0	2DJPX@1|root,32UDI@2|Bacteria,2IIFD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3859356_5	930171.Asphe3_28550	8.668e-11	66.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,1W86R@1268|Micrococcaceae	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HKD2_k127_3877106_4	1150398.JIBJ01000007_gene72	9.427e-77	258.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,1W8JW@1268|Micrococcaceae	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_3877106_6	1276920.ADIAG_02048	4.377e-30	125.0	2DRKY@1|root,33C8C@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4282
HKD2_k127_3877106_2	1151118.KB895784_gene3230	3.75e-133	429.0	COG3336@1|root,COG3336@2|Bacteria,2I8JX@201174|Actinobacteria	201174|Actinobacteria	S	cytochrome C oxidase	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG
HKD2_k127_3877106_3	1151119.KB895501_gene2866	4.754e-80	296.0	COG2755@1|root,COG2755@2|Bacteria,2HTH2@201174|Actinobacteria,1W9XH@1268|Micrococcaceae	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_3877106_1	1150398.JIBJ01000007_gene84	7.255e-192	612.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,1WB4K@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
HKD2_k127_3877106_5	1449044.JMLE01000028_gene261	8.901e-57	204.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_3,Flavodoxin_5
HKD2_k127_3877106_0	290399.Arth_3962	1.902e-206	649.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,1W8IY@1268|Micrococcaceae	201174|Actinobacteria	E	alcohol dehydrogenase	adh	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
HKD2_k127_3877106_8	1150398.JIBJ01000007_gene88	3.332e-25	119.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,1W9FU@1268|Micrococcaceae	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD2_k127_387852_0	1150398.JIBJ01000006_gene3463	4.276e-223	692.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,1W7QJ@1268|Micrococcaceae	201174|Actinobacteria	C	methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_3880022_1	1158050.KB895471_gene2585	3.327e-157	500.0	COG2224@1|root,COG2224@2|Bacteria,2GNAY@201174|Actinobacteria,1W7KS@1268|Micrococcaceae	201174|Actinobacteria	C	Isocitrate lyase	aceA	GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
HKD2_k127_3880022_0	290399.Arth_0584	4.278e-307	944.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,2GMWU@201174|Actinobacteria,1W7QE@1268|Micrococcaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
HKD2_k127_3880022_2	1151119.KB895499_gene3694	7.282e-81	273.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,1W851@1268|Micrococcaceae	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	poxB	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD2_k127_3882748_0	106370.Francci3_0121	7.872e-167	536.0	COG3385@1|root,COG3385@2|Bacteria,2ICCW@201174|Actinobacteria	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
HKD2_k127_3882748_2	1089545.KB913037_gene846	1.696e-20	97.0	2C56A@1|root,323M1@2|Bacteria,2I5ZX@201174|Actinobacteria,4EE21@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3882748_1	1114959.SZMC14600_18584	1.393e-49	187.0	2B9V1@1|root,32380@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
HKD2_k127_3892752_0	1150398.JIBJ01000009_gene463	4.741e-118	383.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria	201174|Actinobacteria	S	maleylpyruvate isomerase	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_C,MDMPI_N
HKD2_k127_3892752_1	1077972.ARGLB_016_00060	2.832e-77	271.0	COG0350@1|root,COG0350@2|Bacteria,2IHP1@201174|Actinobacteria,1W9PC@1268|Micrococcaceae	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1
HKD2_k127_3892752_2	1150398.JIBJ01000009_gene465	7.39e-68	235.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,1W842@1268|Micrococcaceae	201174|Actinobacteria	FL	AlkA N-terminal domain	alkA	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
HKD2_k127_3900848_1	1150398.JIBJ01000006_gene3644	1.625e-72	247.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,1W7YM@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,ACT_6,Formyl_trans_N
HKD2_k127_3900848_0	1101188.KI912155_gene2374	2.476e-267	825.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,1W82M@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD2_k127_3901564_0	1150398.JIBJ01000004_gene2720	2.743e-176	557.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GIU4@201174|Actinobacteria,1W8AN@1268|Micrococcaceae	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
HKD2_k127_3901564_1	1150398.JIBJ01000004_gene2719	6.747e-66	226.0	COG2813@1|root,COG2813@2|Bacteria,2I8VY@201174|Actinobacteria,1W8WK@1268|Micrococcaceae	201174|Actinobacteria	J	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA	rlmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.172,2.1.1.174	ko:K00564,ko:K11391	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
HKD2_k127_391073_0	1150398.JIBJ01000006_gene3537	1.205e-260	829.0	COG1474@1|root,COG2197@1|root,COG1474@2|Bacteria,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria,1WAFR@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HKD2_k127_391073_1	1150398.JIBJ01000006_gene3538	1.028e-70	242.0	COG2909@1|root,COG2909@2|Bacteria,2GM03@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,GerE
HKD2_k127_3912882_1	290399.Arth_3478	6.347e-64	222.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,1W8BP@1268|Micrococcaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD2_k127_3912882_0	1150398.JIBJ01000012_gene2071	1.571e-220	692.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,1W904@1268|Micrococcaceae	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
HKD2_k127_3921131_11	1449044.JMLE01000019_gene1708	1.597e-12	68.0	2DRB9@1|root,33B2J@2|Bacteria,2GX8G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3921131_3	290399.Arth_4102	2.638e-168	545.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_3921131_6	1150398.JIBJ01000007_gene190	8.747e-94	309.0	COG5516@1|root,COG5516@2|Bacteria,2GNZF@201174|Actinobacteria,1WA53@1268|Micrococcaceae	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
HKD2_k127_3921131_10	1349820.M707_15070	1.911e-44	165.0	2FA57@1|root,342DZ@2|Bacteria,2GT3P@201174|Actinobacteria,1W9V1@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3921131_8	1150398.JIBJ01000007_gene192	5.868e-75	256.0	COG3247@1|root,COG3247@2|Bacteria,2GS60@201174|Actinobacteria,1WA6K@1268|Micrococcaceae	201174|Actinobacteria	S	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
HKD2_k127_3921131_1	1449044.JMLE01000019_gene1713	6.312e-214	671.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,1W7SB@1268|Micrococcaceae	201174|Actinobacteria	V	MATE efflux family protein	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD2_k127_3921131_2	1150398.JIBJ01000007_gene195	6.549e-190	613.0	COG1607@1|root,COG1607@2|Bacteria,2GK6X@201174|Actinobacteria,1W8U1@1268|Micrococcaceae	201174|Actinobacteria	I	Thioesterase superfamily	-	-	3.1.2.23	ko:K01075,ko:K10806	ko00130,ko00362,ko01040,ko01100,ko01110,ko01120,map00130,map00362,map01040,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
HKD2_k127_3921131_0	1077972.ARGLB_037_00080	3.755e-291	896.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,1W8BX@1268|Micrococcaceae	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
HKD2_k127_3921131_5	1158050.KB895461_gene2939	1.006e-103	340.0	COG0431@1|root,COG0431@2|Bacteria,2IHWU@201174|Actinobacteria,1W97G@1268|Micrococcaceae	201174|Actinobacteria	S	FMN reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
HKD2_k127_3921131_4	290340.AAur_4160	1.384e-134	435.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,1W877@1268|Micrococcaceae	201174|Actinobacteria	S	thymidilate synthase from Mycobacterium tuberculosis. Many phenazine compounds are found in nature and are produced by bacteria such as Pseudomonas spp., Streptomyces spp., and Pantoea agglomerans. These compounds have been implicated in the virulence and competitive fitness of producing organisms. For example, the phenazine pyocyanin produced by Pseudomonas aeruginosa contributes to its ability to colonise the lungs of cystic fibrosis patients. Similarly, phenazine-1-carboxylic acid, produced by a number of Pseudomonas, increases survival in soil environments and has been shown to be essential for the biological control activity of certain strains	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
HKD2_k127_3921131_7	1150398.JIBJ01000007_gene202	1.057e-84	283.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,1W8YX@1268|Micrococcaceae	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HKD2_k127_3923701_0	290399.Arth_2724	4.875e-292	900.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,1WB5K@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD2_k127_3923701_1	290399.Arth_2727	1.713e-230	727.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,1W80K@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD2_k127_3923701_2	1150398.JIBJ01000010_gene521	1.039e-224	700.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,1W8C2@1268|Micrococcaceae	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD2_k127_3923701_3	1150398.JIBJ01000010_gene520	4.135e-135	439.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_3934831_3	930171.Asphe3_17500	8.603e-77	266.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,1W95E@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_3934831_1	290399.Arth_0473	5.285e-137	441.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
HKD2_k127_3934831_2	1151119.KB895491_gene1877	2.063e-135	438.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
HKD2_k127_3934831_0	1449044.JMLE01000029_gene139	0.0	1062.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,1W8NY@1268|Micrococcaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
HKD2_k127_3935989_1	1151119.KB895503_gene3077	2.225e-148	484.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,1W7R2@1268|Micrococcaceae	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD2_k127_3935989_0	1150398.JIBJ01000001_gene1404	1.595e-155	495.0	COG0514@1|root,COG1040@1|root,COG0514@2|Bacteria,COG1040@2|Bacteria,2GJSS@201174|Actinobacteria,1W88N@1268|Micrococcaceae	201174|Actinobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
HKD2_k127_3956880_3	1150398.JIBJ01000011_gene2330	3.609e-16	79.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
HKD2_k127_3956880_2	1077972.ARGLB_085_02050	3.847e-88	296.0	COG3396@1|root,COG3396@2|Bacteria,2GKXZ@201174|Actinobacteria,1WAIV@1268|Micrococcaceae	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
HKD2_k127_3956880_0	1150398.JIBJ01000011_gene2332	5.314e-276	855.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,1W8GM@1268|Micrococcaceae	201174|Actinobacteria	K	RNB	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
HKD2_k127_3956880_1	1197706.AKKK01000013_gene2060	1.248e-256	793.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,1W7PX@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HKD2_k127_395833_0	1150398.JIBJ01000006_gene3689	1.315e-184	589.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
HKD2_k127_395833_1	1150398.JIBJ01000006_gene3688	5.016e-136	437.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
HKD2_k127_3971520_1	290399.Arth_2102	1.126e-57	220.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,1W8XU@1268|Micrococcaceae	201174|Actinobacteria	K	Winged helix-turn-helix DNA-binding	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
HKD2_k127_3971520_0	1150398.JIBJ01000004_gene3045	4.055e-160	508.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,1W7NC@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_3977144_2	1077972.ARGLB_013_00060	2.539e-101	332.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,1W9GW@1268|Micrococcaceae	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HKD2_k127_3977144_1	1150398.JIBJ01000009_gene368	6.485e-202	633.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,1W7IA@1268|Micrococcaceae	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HKD2_k127_3977144_4	290399.Arth_1415	8.179e-48	175.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,1WA8F@1268|Micrococcaceae	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
HKD2_k127_3977144_0	290399.Arth_1416	0.0	1628.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,1W85P@1268|Micrococcaceae	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HKD2_k127_3977144_3	452863.Achl_1427	9.176e-76	259.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,1W9KS@1268|Micrococcaceae	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD2_k127_3981750_10	1150398.JIBJ01000015_gene1988	5.478e-125	400.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,1W7ZQ@1268|Micrococcaceae	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
HKD2_k127_3981750_12	1158050.KB895452_gene123	1.103e-55	196.0	2CAFG@1|root,32RRB@2|Bacteria,2IQ98@201174|Actinobacteria,1W9TC@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
HKD2_k127_3981750_3	1150398.JIBJ01000015_gene1993	3.956e-211	665.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,1W7EQ@1268|Micrococcaceae	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HKD2_k127_3981750_8	290399.Arth_2594	5.145e-150	480.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,1W90S@1268|Micrococcaceae	201174|Actinobacteria	O	Tetratricopeptide repeat	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
HKD2_k127_3981750_2	290399.Arth_2595	3.48e-276	861.0	2DKU3@1|root,30ATH@2|Bacteria,2I4Z7@201174|Actinobacteria,1W862@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3981750_4	1449044.JMLE01000005_gene593	1.342e-202	637.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,1W7V8@1268|Micrococcaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD2_k127_3981750_7	1150398.JIBJ01000015_gene1997	2.493e-152	484.0	COG2945@1|root,COG2945@2|Bacteria,2GP8G@201174|Actinobacteria,1W84B@1268|Micrococcaceae	201174|Actinobacteria	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_6
HKD2_k127_3981750_13	1158050.KB895452_gene134	6.366e-54	193.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,1WA0J@1268|Micrococcaceae	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3981750_9	1150398.JIBJ01000015_gene1999	4.164e-138	448.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,1W8CI@1268|Micrococcaceae	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
HKD2_k127_3981750_14	930171.Asphe3_24630	3.925e-39	145.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,1W9PW@1268|Micrococcaceae	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_3981750_0	1150398.JIBJ01000015_gene2001	0.0	1311.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156
HKD2_k127_3981750_5	1150398.JIBJ01000015_gene2002	1.229e-193	614.0	COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,1W7TM@1268|Micrococcaceae	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD2_k127_3981750_11	290340.AAur_2593	1.879e-77	261.0	2E6YX@1|root,331I5@2|Bacteria,2IFIG@201174|Actinobacteria,1W9H9@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2550)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2550
HKD2_k127_3981750_15	1121360.AUAQ01000015_gene1890	2.812e-15	83.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria,22NGR@1653|Corynebacteriaceae	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
HKD2_k127_3981750_1	1150398.JIBJ01000015_gene2005	4.087e-308	947.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,1W7K4@1268|Micrococcaceae	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD2_k127_3981750_6	290399.Arth_2606	1.071e-159	505.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,1W86S@1268|Micrococcaceae	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HKD2_k127_3986303_2	290340.AAur_2266	3.207e-55	196.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,1W8FY@1268|Micrococcaceae	201174|Actinobacteria	EF	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
HKD2_k127_3986303_1	1150398.JIBJ01000004_gene2889	3.351e-75	258.0	COG0505@1|root,COG0505@2|Bacteria,2GM9I@201174|Actinobacteria,1W9DR@1268|Micrococcaceae	201174|Actinobacteria	EF	Belongs to the CarA family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3986303_0	1150398.JIBJ01000004_gene2888	8.586e-154	486.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,1W7JS@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD2_k127_3993456_2	1077972.ARGLB_051_01010	8.866e-178	558.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria,1W8P5@1268|Micrococcaceae	201174|Actinobacteria	J	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD2_k127_3993456_5	1150398.JIBJ01000014_gene2457	3.203e-27	111.0	2EHMB@1|root,33BD3@2|Bacteria,2GR7D@201174|Actinobacteria,1WA35@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3993456_4	1449044.JMLE01000017_gene1395	3.957e-102	340.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,1W958@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD2_k127_3993456_3	290399.Arth_1591	4.816e-159	505.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,1W8FM@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HKD2_k127_3993456_1	1150398.JIBJ01000014_gene2462	2.001e-298	916.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,1W7XJ@1268|Micrococcaceae	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD2_k127_3993456_0	452863.Achl_1592	0.0	1238.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,1W7KP@1268|Micrococcaceae	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
HKD2_k127_4006370_3	1150398.JIBJ01000006_gene3624	1.949e-58	203.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria,1W97P@1268|Micrococcaceae	201174|Actinobacteria	O	Organic hydroperoxide resistance protein	ohr	-	-	-	-	-	-	-	-	-	-	-	OsmC
HKD2_k127_4006370_1	1150398.JIBJ01000006_gene3623	4.718e-191	605.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,1W85N@1268|Micrococcaceae	201174|Actinobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
HKD2_k127_4006370_0	1158050.KB895456_gene1947	2.007e-214	668.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,1W86W@1268|Micrococcaceae	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HKD2_k127_4006370_2	1158050.KB895456_gene1946	8.696e-88	294.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,1W8HD@1268|Micrococcaceae	201174|Actinobacteria	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HKD2_k127_40092_2	290399.Arth_0417	7.685e-181	576.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,1W911@1268|Micrococcaceae	201174|Actinobacteria	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
HKD2_k127_40092_5	1449044.JMLE01000047_gene3688	8.315e-34	132.0	293PN@1|root,2ZR5B@2|Bacteria,2GZX7@201174|Actinobacteria,1WAE4@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_40092_3	1449044.JMLE01000047_gene3687	5.89e-175	550.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,1W99D@1268|Micrococcaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	sugD	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HKD2_k127_40092_1	1150398.JIBJ01000002_gene1132	3.822e-196	614.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,1W887@1268|Micrococcaceae	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	sugC	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HKD2_k127_40092_0	290399.Arth_0413	1.549e-232	724.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,1W8PA@1268|Micrococcaceae	201174|Actinobacteria	G	extracellular solute-binding protein	sugB	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HKD2_k127_40092_4	290399.Arth_0411	9.517e-75	254.0	2FGZC@1|root,348UG@2|Bacteria,2GVEP@201174|Actinobacteria,1WB97@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4016070_0	1150398.JIBJ01000005_gene3086	2.954e-237	736.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,1W7ZC@1268|Micrococcaceae	201174|Actinobacteria	CH	Phenol hydroxylase, C-terminal dimerisation domain	-	-	1.14.13.7	ko:K03380	ko00623,ko00627,ko01120,map00623,map00627,map01120	-	R00815,R03566	RC00046,RC00236	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Phe_hydrox_dim
HKD2_k127_4016070_1	452863.Achl_3608	1.183e-95	314.0	COG0179@1|root,COG0684@1|root,COG0179@2|Bacteria,COG0684@2|Bacteria,2GN1K@201174|Actinobacteria,1W81V@1268|Micrococcaceae	201174|Actinobacteria	HQ	Aldolase/RraA	hpaG	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase,RraA-like
HKD2_k127_4021837_0	1150398.JIBJ01000005_gene3377	1.222e-303	944.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,1W8H6@1268|Micrococcaceae	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD2_k127_4021837_2	290399.Arth_2882	9.249e-140	450.0	COG1808@1|root,COG1808@2|Bacteria,2GJQ4@201174|Actinobacteria,1W800@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
HKD2_k127_4021837_1	290399.Arth_2880	1.836e-296	916.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,1W8H6@1268|Micrococcaceae	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD2_k127_4040354_2	43759.JNWK01000071_gene4586	3.869e-41	160.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
HKD2_k127_4040354_1	1151119.KB895496_gene3880	1.536e-88	304.0	COG3707@1|root,COG3707@2|Bacteria,2I8E6@201174|Actinobacteria	201174|Actinobacteria	K	Antar domain	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,PAS_3
HKD2_k127_4040354_0	1150398.JIBJ01000002_gene1109	0.0	1133.0	COG0531@1|root,COG0531@2|Bacteria,2GM81@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4055812_2	290399.Arth_4139	1.011e-84	286.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,1W8F6@1268|Micrococcaceae	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_4055812_1	290399.Arth_4140	5.352e-115	375.0	COG1349@1|root,COG1349@2|Bacteria,2GJK9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, deor family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HKD2_k127_4055812_0	1150398.JIBJ01000007_gene217	0.0	1099.0	COG0488@1|root,COG0488@2|Bacteria,2GMUD@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD2_k127_4055812_3	930171.Asphe3_39620	8.082e-18	82.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,1W85I@1268|Micrococcaceae	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	pbp2B	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	MecA_N,PBP_dimer,Transpeptidase
HKD2_k127_4067041_0	290399.Arth_3273	8.52e-177	559.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,1W8VG@1268|Micrococcaceae	201174|Actinobacteria	E	PFAM Amino acid	ansP	-	-	ko:K11738	-	-	-	-	ko00000,ko02000	2.A.3.1.8	-	-	AA_permease
HKD2_k127_4067041_1	1077972.ARGLB_008_00650	5.19e-69	237.0	COG1266@1|root,COG1266@2|Bacteria,2IPC6@201174|Actinobacteria,1W9EW@1268|Micrococcaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD2_k127_4074652_0	290399.Arth_1263	3.264e-150	476.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,1W8BM@1268|Micrococcaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD2_k127_4074652_1	1906.SFRA_02315	3.621e-48	179.0	COG1309@1|root,COG1309@2|Bacteria,2GPKZ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_4074652_2	1906.SFRA_02310	4.263e-47	181.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_4096938_0	1304876.AZVC01000015_gene3820	1.503e-120	387.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,1W8FT@1268|Micrococcaceae	201174|Actinobacteria	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD2_k127_4096938_1	290399.Arth_0674	1.719e-110	363.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria	201174|Actinobacteria	Q	oxidoreductase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,DAO,NAD_binding_8
HKD2_k127_4108359_2	290399.Arth_2168	5.113e-07	51.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,1W861@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
HKD2_k127_4108359_0	1115632.JAFW01000001_gene74	2.321e-160	513.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,1W7GW@1268|Micrococcaceae	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD2_k127_4108359_1	290399.Arth_2166	9.273e-134	432.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,1W8QR@1268|Micrococcaceae	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
HKD2_k127_4186590_0	1150398.JIBJ01000015_gene1959	6.831e-221	696.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,1W7WF@1268|Micrococcaceae	201174|Actinobacteria	E	amino acid	aroP	-	-	ko:K03293,ko:K11735,ko:K16237	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.12,2.A.3.1.4,2.A.3.1.5	-	-	AA_permease
HKD2_k127_4225138_0	1150398.JIBJ01000003_gene1859	1.394e-181	574.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,1W7DQ@1268|Micrococcaceae	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0034641,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD2_k127_4225200_2	290399.Arth_3448	8.006e-67	229.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,1W9QM@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD2_k127_4225200_3	930171.Asphe3_33630	4.897e-15	79.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ
HKD2_k127_4225200_0	1150398.JIBJ01000012_gene2057	3.849e-81	273.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
HKD2_k127_4271381_0	290399.Arth_1070	4.623e-175	552.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,1W7H1@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	mgtA	GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12583	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD2_k127_4271381_2	1151119.KB895501_gene2873	3.947e-36	138.0	2EF7K@1|root,3390K@2|Bacteria,2GQM6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4271381_1	1150398.JIBJ01000006_gene3684	1.179e-36	140.0	COG2268@1|root,COG2268@2|Bacteria,2GK9I@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Flot
HKD2_k127_4279301_4	1158050.KB895463_gene3771	2.253e-70	245.0	COG0640@1|root,COG0640@2|Bacteria,2GTPG@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HKD2_k127_4279301_1	1150398.JIBJ01000008_gene662	2.784e-189	595.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD2_k127_4279301_0	1150398.JIBJ01000008_gene663	4.011e-261	812.0	COG2271@1|root,COG2271@2|Bacteria,2GIS1@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_4279301_2	1150398.JIBJ01000008_gene664	1.71e-136	443.0	COG1028@1|root,COG1028@2|Bacteria,2GP5H@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HKD2_k127_4279301_3	1150398.JIBJ01000008_gene665	2.169e-94	322.0	COG3246@1|root,COG3246@2|Bacteria,2I9EQ@201174|Actinobacteria	201174|Actinobacteria	K	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
HKD2_k127_4284643_4	1449044.JMLE01000011_gene3385	1.116e-07	53.0	2EHMU@1|root,33BDI@2|Bacteria,2HZH7@201174|Actinobacteria,1WABZ@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
HKD2_k127_4284643_0	290399.Arth_0718	1.258e-215	677.0	COG0626@1|root,COG0626@2|Bacteria,2GMD8@201174|Actinobacteria,1W83S@1268|Micrococcaceae	201174|Actinobacteria	E	cystathionine gamma-synthase	metB	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
HKD2_k127_4284643_2	1449044.JMLE01000011_gene3387	1e-102	343.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,1W963@1268|Micrococcaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
HKD2_k127_4284643_1	452863.Achl_0842	2.568e-208	660.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,1W7G2@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase III	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
HKD2_k127_4284643_3	1150398.JIBJ01000001_gene1376	1.54e-37	145.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria,1W7Q9@1268|Micrococcaceae	201174|Actinobacteria	M	TAP-like protein	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
HKD2_k127_4292771_0	1150398.JIBJ01000004_gene2833	3.021e-236	737.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,1W8NQ@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HKD2_k127_4292771_8	1150398.JIBJ01000004_gene2832	4.928e-44	164.0	2DGAK@1|root,2ZV5P@2|Bacteria,2GUTC@201174|Actinobacteria,1W9ST@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4292771_5	290399.Arth_2320	8.098e-70	239.0	2B5TA@1|root,31YNZ@2|Bacteria,2H112@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4292771_6	1150398.JIBJ01000004_gene2830	1.797e-48	175.0	COG1605@1|root,COG1605@2|Bacteria,2GT4M@201174|Actinobacteria	201174|Actinobacteria	E	Chorismate mutase type II	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
HKD2_k127_4292771_4	290399.Arth_2322	6.324e-73	247.0	COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria,1WC1Q@1268|Micrococcaceae	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD2_k127_4292771_2	290399.Arth_2323	4.957e-138	465.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,1W8ZF@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HKD2_k127_4292771_7	290340.AAur_2316	3.595e-46	176.0	COG0695@1|root,COG0695@2|Bacteria,2IQF9@201174|Actinobacteria	201174|Actinobacteria	O	Glutaredoxin	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
HKD2_k127_4292771_1	1150398.JIBJ01000004_gene2825	2.146e-220	687.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,1W8I5@1268|Micrococcaceae	201174|Actinobacteria	C	Mycothiol-dependent formaldehyde dehydrogenase	adhC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_4292771_3	1150398.JIBJ01000004_gene2824	8.078e-115	378.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,1W908@1268|Micrococcaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	blaB4	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HKD2_k127_4292771_9	1150398.JIBJ01000004_gene2823	4.005e-18	86.0	COG2318@1|root,COG2318@2|Bacteria,2IGJQ@201174|Actinobacteria	201174|Actinobacteria	H	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
HKD2_k127_4307463_0	290399.Arth_0731	5.46e-188	589.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,1W7KD@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD2_k127_4307463_1	1197706.AKKK01000009_gene488	3.746e-123	401.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,1W7EC@1268|Micrococcaceae	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
HKD2_k127_4307463_2	290399.Arth_0733	8.328e-97	319.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,1W8MH@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD2_k127_4312799_0	1177594.MIC448_1720007	4.096e-129	429.0	COG0683@1|root,COG0683@2|Bacteria,2IE34@201174|Actinobacteria	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
HKD2_k127_4312799_1	1177594.MIC448_1720006	2.232e-59	211.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_4325151_2	290399.Arth_0644	2.222e-19	90.0	COG0438@1|root,COG0438@2|Bacteria,2H5RV@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD2_k127_4325151_0	1150398.JIBJ01000002_gene904	2.343e-188	602.0	COG3214@1|root,COG3214@2|Bacteria,2HYBB@201174|Actinobacteria,1WB54@1268|Micrococcaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
HKD2_k127_4325151_1	1197706.AKKK01000009_gene594	2.78e-50	179.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,1W9GI@1268|Micrococcaceae	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
HKD2_k127_4327413_2	290399.Arth_3058	8.398e-109	356.0	COG0477@1|root,COG2814@2|Bacteria,2GMBQ@201174|Actinobacteria,1WC3A@1268|Micrococcaceae	201174|Actinobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_4327413_3	290399.Arth_3059	6.056e-85	283.0	COG1733@1|root,COG1733@2|Bacteria,2IP16@201174|Actinobacteria	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD2_k127_4327413_0	1449044.JMLE01000002_gene4507	1.109e-206	660.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,1WAQ5@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
HKD2_k127_4327413_1	290399.Arth_3061	6.122e-118	380.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,1W89J@1268|Micrococcaceae	201174|Actinobacteria	E	cystathionine	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
HKD2_k127_4342733_0	1150398.JIBJ01000007_gene69	1.199e-96	321.0	2BYAG@1|root,2ZC13@2|Bacteria,2IGUZ@201174|Actinobacteria,1WA00@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4342733_1	1101188.KI912156_gene3954	6.336e-64	223.0	COG3012@1|root,COG3012@2|Bacteria,2IQEM@201174|Actinobacteria,1W9RD@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
HKD2_k127_4342733_2	1150398.JIBJ01000007_gene72	4.629e-28	117.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,1W8JW@1268|Micrococcaceae	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_4358979_0	1210884.HG799470_gene14318	6.314e-75	267.0	COG5659@1|root,COG5659@2|Bacteria,2IWRG@203682|Planctomycetes	203682|Planctomycetes	L	best DB hits BLAST gb AAD45539.1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_4364981_0	1077972.ARGLB_010_00510	2.865e-117	383.0	COG4760@1|root,COG4760@2|Bacteria,2GNCK@201174|Actinobacteria,1W8ZB@1268|Micrococcaceae	201174|Actinobacteria	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
HKD2_k127_4364981_1	290399.Arth_1158	2.079e-75	258.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
HKD2_k127_4396626_2	118173.KB235911_gene102	0.0006157	42.0	2B9V1@1|root,32380@2|Bacteria,1GGKW@1117|Cyanobacteria,1HGRP@1150|Oscillatoriales	1117|Cyanobacteria	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
HKD2_k127_4396626_0	886293.Sinac_2157	2.551e-112	378.0	COG3385@1|root,COG3385@2|Bacteria,2J0KK@203682|Planctomycetes	203682|Planctomycetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_4396626_1	886293.Sinac_2040	2.8e-51	204.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
HKD2_k127_4426406_1	290399.Arth_3301	6.546e-36	136.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,1WA40@1268|Micrococcaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HKD2_k127_4426406_0	290399.Arth_3302	2.71e-195	615.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria	201174|Actinobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
HKD2_k127_4434781_4	1150398.JIBJ01000002_gene1258	1.276e-49	179.0	COG1925@1|root,COG3412@1|root,COG1925@2|Bacteria,COG3412@2|Bacteria,2IHRN@201174|Actinobacteria,1WBBT@1268|Micrococcaceae	201174|Actinobacteria	G	PTS system fructose IIA component	dhaM	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man,PTS-HPr
HKD2_k127_4434781_2	1158050.KB895464_gene3569	1.959e-158	505.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,1W7UH@1268|Micrococcaceae	201174|Actinobacteria	L	FES	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD2_k127_4434781_3	1151119.KB895500_gene2815	1.03e-70	245.0	2E5CN@1|root,3304R@2|Bacteria,2GM9T@201174|Actinobacteria,1W9J6@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4434781_0	1150398.JIBJ01000002_gene1254	1.193e-213	665.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,1W83G@1268|Micrococcaceae	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
HKD2_k127_4434781_1	1150398.JIBJ01000002_gene1253	6.526e-209	669.0	COG4108@1|root,COG4108@2|Bacteria,2GKQA@201174|Actinobacteria,1WB6R@1268|Micrococcaceae	201174|Actinobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
HKD2_k127_4491340_0	298653.Franean1_3436	2.119e-288	891.0	COG1321@1|root,COG1321@2|Bacteria,2ICG2@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4491340_1	446470.Snas_5024	3.718e-24	104.0	COG4319@1|root,COG4319@2|Bacteria,2IIFR@201174|Actinobacteria,4F04C@85014|Glycomycetales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD2_k127_4506212_1	930171.Asphe3_19500	2.188e-80	270.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,1W7UY@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD2_k127_4506212_0	1150398.JIBJ01000004_gene2945	3.674e-298	921.0	COG3573@1|root,COG3573@2|Bacteria,2GIYM@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenase	-	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
HKD2_k127_4506212_2	1150398.JIBJ01000004_gene2944	6.446e-60	220.0	COG2267@1|root,COG2267@2|Bacteria,2GIVB@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HKD2_k127_4520089_4	1151119.KB895497_gene3290	6.361e-54	193.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,1W8BP@1268|Micrococcaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD2_k127_4520089_0	1150398.JIBJ01000012_gene2074	3.032e-107	355.0	COG3707@1|root,COG3707@2|Bacteria,2IF8A@201174|Actinobacteria,1W9JA@1268|Micrococcaceae	201174|Actinobacteria	T	ANTAR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
HKD2_k127_4520089_2	452863.Achl_2847	8.476e-88	296.0	COG1075@1|root,COG1075@2|Bacteria,2IHUU@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4520089_1	1150398.JIBJ01000012_gene2075	6.359e-107	353.0	COG2267@1|root,COG2267@2|Bacteria,2IMQQ@201174|Actinobacteria,1WARY@1268|Micrococcaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
HKD2_k127_4520089_5	208444.JNYY01000001_gene5518	1.982e-42	158.0	COG1917@1|root,COG1917@2|Bacteria,2IQ74@201174|Actinobacteria,4ECDH@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4520089_3	1150398.JIBJ01000012_gene2077	1.9e-74	252.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria,1WA7G@1268|Micrococcaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
HKD2_k127_4540055_0	1122138.AQUZ01000137_gene3267	2.508e-154	495.0	COG3547@1|root,COG3547@2|Bacteria,2H56K@201174|Actinobacteria	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HKD2_k127_4557881_2	1197706.AKKK01000015_gene2519	8.756e-30	119.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,1W8MI@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
HKD2_k127_4557881_1	1150398.JIBJ01000006_gene3609	9.555e-158	505.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,1W7XW@1268|Micrococcaceae	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD2_k127_4557881_0	1150398.JIBJ01000006_gene3608	8.437e-181	571.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,1W8AQ@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
HKD2_k127_456584_0	1115632.JAFW01000001_gene399	1.841e-84	286.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria	201174|Actinobacteria	L	DNA alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HKD2_k127_456584_1	1150398.JIBJ01000004_gene2668	4.354e-33	134.0	COG5416@1|root,COG5416@2|Bacteria,2GQTQ@201174|Actinobacteria	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
HKD2_k127_456584_2	290399.Arth_2420	2.188e-22	102.0	COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,1W9UK@1268|Micrococcaceae	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb2	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD2_k127_47391_3	1150398.JIBJ01000010_gene592	2.958e-18	84.0	COG1695@1|root,COG1695@2|Bacteria,2GMKD@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD2_k127_47391_2	1449044.JMLE01000005_gene658	9.987e-42	164.0	COG5662@1|root,COG5662@2|Bacteria,2IRFU@201174|Actinobacteria,1W9R8@1268|Micrococcaceae	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
HKD2_k127_47391_0	1150398.JIBJ01000010_gene590	1.548e-125	408.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,1W8HP@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_47391_1	1077972.ARGLB_085_00660	1.699e-81	276.0	COG2259@1|root,COG2259@2|Bacteria,2HD6Y@201174|Actinobacteria,1W9JP@1268|Micrococcaceae	201174|Actinobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD2_k127_4749385_3	1298860.AUEM01000001_gene1201	4.075e-12	65.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2GMG7@201174|Actinobacteria	201174|Actinobacteria	KT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
HKD2_k127_4749385_0	1121924.ATWH01000002_gene4086	4.099e-188	597.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4FKQR@85023|Microbacteriaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_4749385_1	1121924.ATWH01000002_gene4087	2.873e-55	194.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria,4FQ1G@85023|Microbacteriaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD2_k127_4749385_2	290399.Arth_3611	1.474e-53	189.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria	201174|Actinobacteria	K	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
HKD2_k127_4865602_1	290399.Arth_2397	3.34e-258	799.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,1W87F@1268|Micrococcaceae	201174|Actinobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
HKD2_k127_4865602_0	290399.Arth_2398	7.043e-266	822.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,1W7TY@1268|Micrococcaceae	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HKD2_k127_4875593_4	1151119.KB895516_gene2668	2.026e-56	198.0	COG0730@1|root,COG0730@2|Bacteria,2GMNQ@201174|Actinobacteria,1W7VH@1268|Micrococcaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD2_k127_4875593_0	1150398.JIBJ01000009_gene361	1.034e-246	767.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
HKD2_k127_4875593_1	1150398.JIBJ01000009_gene364	5.017e-136	449.0	COG3570@1|root,COG3570@2|Bacteria,2GNSH@201174|Actinobacteria,1W940@1268|Micrococcaceae	201174|Actinobacteria	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
HKD2_k127_4875593_2	290399.Arth_1411	6.108e-115	374.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,1W8BB@1268|Micrococcaceae	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD2_k127_4875593_3	1150398.JIBJ01000009_gene366	3.827e-57	209.0	2DSVA@1|root,33HJF@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4439
HKD2_k127_48875_1	1150398.JIBJ01000020_gene3838	2.682e-87	293.0	COG3409@1|root,COG3409@2|Bacteria,2IM37@201174|Actinobacteria,1WBE2@1268|Micrococcaceae	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_48875_3	1349820.M707_17285	3.496e-28	122.0	COG1699@1|root,COG1699@2|Bacteria	2|Bacteria	S	bacterial-type flagellum assembly	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
HKD2_k127_48875_0	1150398.JIBJ01000020_gene3836	1.285e-126	412.0	COG1344@1|root,COG1344@2|Bacteria,2IA40@201174|Actinobacteria	201174|Actinobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
HKD2_k127_48875_2	452863.Achl_3000	1.081e-64	228.0	COG1256@1|root,COG1256@2|Bacteria,2GNXQ@201174|Actinobacteria	201174|Actinobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD2_k127_4901945_1	290340.AAur_2301	3.948e-69	237.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,1W90D@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
HKD2_k127_4901945_0	1150398.JIBJ01000004_gene2845	6.449e-250	779.0	COG0770@1|root,COG0770@2|Bacteria,2I2EU@201174|Actinobacteria,1W7KI@1268|Micrococcaceae	201174|Actinobacteria	M	Mur ligase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
HKD2_k127_4901945_2	1150398.JIBJ01000004_gene2844	3.754e-52	197.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,1W7IS@1268|Micrococcaceae	201174|Actinobacteria	S	glutamine amidotransferase	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
HKD2_k127_49441_0	1150398.JIBJ01000003_gene1881	2.795e-317	976.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,1W7M8@1268|Micrococcaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HKD2_k127_49441_1	1077972.ARGLB_039_00020	3.07e-18	85.0	COG0346@1|root,COG0346@2|Bacteria,2H9P4@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD2_k127_4972140_1	1150398.JIBJ01000010_gene586	2.776e-160	505.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,1W7J9@1268|Micrococcaceae	201174|Actinobacteria	G	Inositol monophosphatase family	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HKD2_k127_4972140_0	1150398.JIBJ01000010_gene587	3.146e-206	643.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,1W86A@1268|Micrococcaceae	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
HKD2_k127_5003093_0	1077972.ARGLB_054_00650	4.739e-135	436.0	COG3290@1|root,COG3290@2|Bacteria,2GIRZ@201174|Actinobacteria,1W8SW@1268|Micrococcaceae	201174|Actinobacteria	T	Signal transduction histidine kinase regulating citrate malate metabolism	citA	-	2.7.13.3	ko:K02476	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,SPOB_a,sCache_3_2
HKD2_k127_5003093_1	1349820.M707_05210	1.148e-120	392.0	COG2851@1|root,COG2851@2|Bacteria,2GNWE@201174|Actinobacteria,1W8T6@1268|Micrococcaceae	201174|Actinobacteria	C	Citrate transporter	citN	-	-	ko:K03300	-	-	-	-	ko00000	2.A.11	-	-	CitMHS
HKD2_k127_5007823_2	1132441.KI519454_gene1147	8.502e-79	275.0	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria,1W7YU@1268|Micrococcaceae	201174|Actinobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
HKD2_k127_5007823_1	1150398.JIBJ01000002_gene954	2.122e-211	671.0	COG2141@1|root,COG2141@2|Bacteria,2GNR5@201174|Actinobacteria,1W8RQ@1268|Micrococcaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_5007823_0	1449044.JMLE01000008_gene2146	1.657e-216	673.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,1W8FV@1268|Micrococcaceae	201174|Actinobacteria	S	alcohol dehydrogenase	adhC	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_5009379_0	1133849.O3I_024350	4.006e-131	438.0	COG3464@1|root,COG4584@1|root,COG3464@2|Bacteria,COG4584@2|Bacteria,2I7EH@201174|Actinobacteria,4FX9S@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
HKD2_k127_5009379_2	479432.Sros_2012	4.201e-17	83.0	297NG@1|root,2ZUVE@2|Bacteria,2ISFI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5009379_1	479432.Sros_2013	6.709e-40	154.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
HKD2_k127_5010838_3	1151119.KB895500_gene2721	1.569e-89	300.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,1WBIH@1268|Micrococcaceae	201174|Actinobacteria	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
HKD2_k127_5010838_1	1151119.KB895500_gene2720	1.415e-115	392.0	COG0524@1|root,COG0524@2|Bacteria,2GMD4@201174|Actinobacteria,1WB4R@1268|Micrococcaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HKD2_k127_5010838_0	1115632.JAFW01000001_gene2836	1.052e-268	828.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,1W81J@1268|Micrococcaceae	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	rspA	GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD2_k127_5010838_2	1150398.JIBJ01000012_gene2063	3.38e-109	359.0	COG0671@1|root,COG0671@2|Bacteria,2HGNW@201174|Actinobacteria,1WA3K@1268|Micrococcaceae	201174|Actinobacteria	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_5010838_4	1150398.JIBJ01000012_gene2062	1.047e-38	147.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,1WBUP@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
HKD2_k127_5010838_6	290399.Arth_3448	4.21e-24	102.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,1W9QM@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD2_k127_503540_2	290399.Arth_1595	4.552e-65	223.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,1W836@1268|Micrococcaceae	201174|Actinobacteria	P	Bacterial extracellular solute-binding proteins, family 3	glnP	-	-	ko:K02029,ko:K02030,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1,SBP_bac_3
HKD2_k127_503540_0	290399.Arth_1596	2.087e-144	459.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,1W7PY@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HKD2_k127_503540_1	290399.Arth_1598	1.139e-67	237.0	COG1670@1|root,COG1670@2|Bacteria,2GX51@201174|Actinobacteria,1WBW8@1268|Micrococcaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_503540_3	1123322.KB904677_gene3122	2.36e-57	204.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
HKD2_k127_503540_4	1077972.ARGLB_051_00920	6.454e-57	198.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,1W84K@1268|Micrococcaceae	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD2_k127_5056562_0	13689.BV96_04745	3.188e-91	319.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2K2UN@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
HKD2_k127_5056562_1	1331060.RLDS_25170	6.255e-07	53.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria,2K0MX@204457|Sphingomonadales	204457|Sphingomonadales	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
HKD2_k127_5070890_3	1449044.JMLE01000023_gene180	1.264e-30	121.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,1W831@1268|Micrococcaceae	201174|Actinobacteria	I	3-oxoacid CoA-transferase, B subunit	scoB	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2503c	CoA_trans
HKD2_k127_5070890_2	1151119.KB895509_gene409	2.527e-93	313.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,1W93S@1268|Micrococcaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HKD2_k127_5070890_0	1449044.JMLE01000023_gene182	1.037e-152	488.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,1W8AM@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0071704	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HKD2_k127_5070890_1	1150398.JIBJ01000009_gene345	2.347e-101	335.0	COG4565@1|root,COG4565@2|Bacteria,2GMAN@201174|Actinobacteria	201174|Actinobacteria	T	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,Response_reg
HKD2_k127_5074398_1	886293.Sinac_7019	5.131e-28	127.0	COG5549@1|root,COG5549@2|Bacteria,2J1GF@203682|Planctomycetes	203682|Planctomycetes	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Peptidase_M10
HKD2_k127_5108360_0	649747.HMPREF0083_03041	4.687e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1VKSM@1239|Firmicutes,4IBSI@91061|Bacilli,2701Q@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
HKD2_k127_5125507_0	251229.Chro_2396	7.102e-39	153.0	COG0607@1|root,COG0607@2|Bacteria,1G8N9@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_5125507_1	861299.J421_2955	2.569e-36	143.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	srpB	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
HKD2_k127_5125507_3	90814.KL370891_gene780	2.438e-06	49.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5125507_2	887929.HMP0721_2517	1.644e-08	55.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5131726_0	1077972.ARGLB_085_02350	4.204e-177	568.0	COG0477@1|root,COG0477@2|Bacteria,2I48M@201174|Actinobacteria,1WAYK@1268|Micrococcaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD2_k127_5131726_2	1158050.KB895452_gene341	5.637e-24	104.0	2DRKW@1|root,33C7X@2|Bacteria,2GX14@201174|Actinobacteria,1WACN@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5131726_1	1077972.ARGLB_085_02340	7.677e-25	104.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,1W9H7@1268|Micrococcaceae	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
HKD2_k127_5133483_1	290399.Arth_2063	8.377e-137	449.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,1W7EA@1268|Micrococcaceae	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD2_k127_5133483_3	1077972.ARGLB_091_00540	1.471e-69	240.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,1W9AU@1268|Micrococcaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD2_k127_5133483_2	1150398.JIBJ01000004_gene3003	7.011e-84	281.0	COG0262@1|root,COG0262@2|Bacteria,2GW2Y@201174|Actinobacteria,1WA3Z@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD2_k127_5133483_4	1150398.JIBJ01000004_gene3002	1.105e-28	115.0	2ESB2@1|root,33JVS@2|Bacteria,2I89P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5133483_0	1449044.JMLE01000001_gene4126	1.745e-216	676.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,1W8GS@1268|Micrococcaceae	201174|Actinobacteria	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD2_k127_5135343_1	1150398.JIBJ01000002_gene1065	3.126e-135	433.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Abhydrolase_1,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,Sulfotransfer_3,Thioesterase,ketoacyl-synt
HKD2_k127_5135343_0	290399.Arth_0515	2.21e-171	540.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,1W86Y@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	nagD	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
HKD2_k127_5135343_2	1150398.JIBJ01000002_gene1063	8.126e-131	418.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,1W7E6@1268|Micrococcaceae	201174|Actinobacteria	J	rRNA methyltransferase	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HKD2_k127_5135343_3	1121924.ATWH01000010_gene930	1.835e-08	55.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4FK83@85023|Microbacteriaceae	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD2_k127_5137162_0	1150398.JIBJ01000002_gene1068	2.762e-105	345.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,1W8RG@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HKD2_k127_5137162_1	1158050.KB895455_gene1715	2.033e-95	330.0	COG0365@1|root,COG0365@2|Bacteria,2GNE8@201174|Actinobacteria,1WB4P@1268|Micrococcaceae	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5146909_5	1121924.ATWH01000010_gene930	1.638e-38	148.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4FK83@85023|Microbacteriaceae	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD2_k127_5146909_2	1150398.JIBJ01000002_gene1061	2.51e-214	666.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,1W8G1@1268|Micrococcaceae	201174|Actinobacteria	G	fructose-bisphosphate aldolase	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HKD2_k127_5146909_4	1158050.KB895463_gene3778	2.105e-77	268.0	2BNGC@1|root,32H4D@2|Bacteria,2I8BD@201174|Actinobacteria,1W9H2@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
HKD2_k127_5146909_3	1150398.JIBJ01000002_gene1059	2.245e-120	390.0	COG1573@1|root,COG1573@2|Bacteria,2IKC9@201174|Actinobacteria	201174|Actinobacteria	L	uracil-dna glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5146909_0	1150398.JIBJ01000002_gene1058	1.932e-249	772.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,1W8SE@1268|Micrococcaceae	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE2	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
HKD2_k127_5146909_1	1151119.KB895513_gene117	3.287e-218	678.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,1W7UU@1268|Micrococcaceae	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD2_k127_5154083_1	1150398.JIBJ01000008_gene684	1.693e-86	289.0	COG3758@1|root,COG3758@2|Bacteria,2IFWP@201174|Actinobacteria	201174|Actinobacteria	S	HutD	ves	-	-	ko:K09975	-	-	-	-	ko00000	-	-	-	HutD
HKD2_k127_5154083_0	290399.Arth_3759	1.44e-89	298.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,1WC12@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HKD2_k127_5154083_2	1151119.KB895497_gene3392	4.39e-05	46.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	yvnB	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	LTD,Laminin_G_3,Metallophos
HKD2_k127_5159849_0	1158050.KB895453_gene1145	4.172e-129	425.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,1W8DA@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HKD2_k127_5159849_1	1158050.KB895461_gene2978	8.55e-41	160.0	COG0845@1|root,COG0845@2|Bacteria,2H154@201174|Actinobacteria	201174|Actinobacteria	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD2_k127_5162768_0	1449044.JMLE01000001_gene4055	7.977e-153	484.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,1W83K@1268|Micrococcaceae	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
HKD2_k127_5162768_3	1150398.JIBJ01000013_gene2577	8.387e-134	429.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,1W8HE@1268|Micrococcaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD2_k127_5162768_1	1101188.KI912155_gene3535	4.536e-146	469.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,1W86K@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HKD2_k127_5162768_4	1449044.JMLE01000001_gene4058	7.769e-127	414.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,1W93B@1268|Micrococcaceae	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
HKD2_k127_5162768_2	1150398.JIBJ01000013_gene2580	2.169e-138	444.0	COG1028@1|root,COG1028@2|Bacteria,2GNX5@201174|Actinobacteria,1W7U1@1268|Micrococcaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_5170961_0	1449044.JMLE01000012_gene3028	9.314e-215	669.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,1W81Y@1268|Micrococcaceae	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
HKD2_k127_5170961_1	290399.Arth_3439	1.522e-91	306.0	COG0546@1|root,COG0546@2|Bacteria,2GIU8@201174|Actinobacteria,1WB9V@1268|Micrococcaceae	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HKD2_k127_5181456_1	1449044.JMLE01000019_gene1708	1.597e-12	68.0	2DRB9@1|root,33B2J@2|Bacteria,2GX8G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5181456_0	1449044.JMLE01000063_gene275	3.693e-294	909.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,1W7IN@1268|Micrococcaceae	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
HKD2_k127_5182054_2	1206731.BAGB01000170_gene4597	1.98e-68	242.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria	201174|Actinobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD2_k127_5182054_1	1280698.AUJS01000032_gene2024	3.773e-87	304.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,27W0D@189330|Dorea	186801|Clostridia	L	Phage integrase SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_5182054_3	913865.DOT_1768	4.144e-64	233.0	COG0582@1|root,COG0582@2|Bacteria,1V2MU@1239|Firmicutes,24FW7@186801|Clostridia,2626W@186807|Peptococcaceae	186801|Clostridia	L	phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD2_k127_5182054_4	913865.DOT_1769	4.46e-63	238.0	COG4974@1|root,COG4974@2|Bacteria,1U0MD@1239|Firmicutes,24FWH@186801|Clostridia,261AT@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
HKD2_k127_5182054_5	1229780.BN381_440002	1.964e-19	89.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria	201174|Actinobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD2_k127_5182054_0	543632.JOJL01000097_gene5165	1.932e-128	421.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_5193148_0	1150398.JIBJ01000008_gene711	0.0	1027.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,1W7XC@1268|Micrococcaceae	201174|Actinobacteria	L	helicase	helZ	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HKD2_k127_5193148_2	1150398.JIBJ01000008_gene706	3.661e-121	395.0	2DBB1@1|root,2Z854@2|Bacteria,2GNBN@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
HKD2_k127_5193148_1	1150398.JIBJ01000008_gene705	5.993e-183	578.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,1W8S9@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HKD2_k127_5193148_3	930171.Asphe3_35700	7.869e-27	109.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1WAIS@1268|Micrococcaceae	201174|Actinobacteria	EGP	transporter	kgtP	-	-	ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2	-	-	MFS_1,Sugar_tr
HKD2_k127_5196740_0	290399.Arth_4154	4.841e-243	758.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,1W9U0@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
HKD2_k127_5196740_1	1150398.JIBJ01000007_gene223	2.786e-171	546.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,1W85C@1268|Micrococcaceae	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
HKD2_k127_5202060_1	479432.Sros_7182	2.364e-09	64.0	COG0582@1|root,COG0582@2|Bacteria,2I8XR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
HKD2_k127_5202060_0	479432.Sros_4677	5.401e-58	205.0	COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria,4EKTT@85012|Streptosporangiales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
HKD2_k127_5204547_4	1150398.JIBJ01000023_gene3897	5.051e-56	198.0	COG2071@1|root,COG2071@2|Bacteria,2HRHB@201174|Actinobacteria,1WBJX@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
HKD2_k127_5204547_3	1077972.ARGLB_083_01400	1.501e-75	256.0	COG3832@1|root,COG3832@2|Bacteria,2IFJT@201174|Actinobacteria,1WA32@1268|Micrococcaceae	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HKD2_k127_5204547_0	1150398.JIBJ01000023_gene3892	6.762e-197	618.0	COG1611@1|root,COG1611@2|Bacteria,2GPA4@201174|Actinobacteria,1WAY2@1268|Micrococcaceae	201174|Actinobacteria	S	Rossmann fold nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
HKD2_k127_5204547_1	1150398.JIBJ01000023_gene3891	8.477e-128	424.0	COG5549@1|root,COG5549@2|Bacteria,2IPE2@201174|Actinobacteria	201174|Actinobacteria	O	Matrixin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
HKD2_k127_5204547_2	1150398.JIBJ01000023_gene3890	8.818e-102	333.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,1W7KV@1268|Micrococcaceae	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD2_k127_5219616_2	930171.Asphe3_09230	6.907e-34	132.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,1W8J4@1268|Micrococcaceae	201174|Actinobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,DUF3553,Helicase_C,RecQ_Zn_bind
HKD2_k127_5219616_1	1449044.JMLE01000021_gene1941	3.801e-41	153.0	COG1254@1|root,COG1254@2|Bacteria,2HTBB@201174|Actinobacteria,1WA6N@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
HKD2_k127_5219616_3	1150398.JIBJ01000011_gene2303	2.5e-28	119.0	COG3422@1|root,COG3422@2|Bacteria	2|Bacteria	S	double-strand break repair	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
HKD2_k127_5219616_0	1150398.JIBJ01000011_gene2306	1.311e-83	285.0	COG0668@1|root,COG0668@2|Bacteria,2GJ51@201174|Actinobacteria,1W8C4@1268|Micrococcaceae	201174|Actinobacteria	M	Mechanosensitive ion channel	mscS	-	-	-	-	-	-	-	-	-	-	-	MS_channel
HKD2_k127_5223711_2	1150398.JIBJ01000006_gene3519	2.291e-41	154.0	COG1959@1|root,COG1959@2|Bacteria,2IFQN@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD2_k127_5223711_0	1449044.JMLE01000031_gene74	1.545e-163	516.0	COG0005@1|root,COG0005@2|Bacteria,2GKEI@201174|Actinobacteria,1W7FK@1268|Micrococcaceae	201174|Actinobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD2_k127_5223711_1	290399.Arth_1263	1.025e-73	255.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,1W8BM@1268|Micrococcaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD2_k127_5243595_2	1449044.JMLE01000034_gene2056	5.137e-122	395.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,1W7JF@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
HKD2_k127_5243595_1	1150398.JIBJ01000012_gene2124	1.353e-144	479.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,1W9JI@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
HKD2_k127_5243595_0	494419.ALPM01000122_gene1272	1.801e-173	555.0	COG0451@1|root,COG0451@2|Bacteria,2GNUX@201174|Actinobacteria	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD2_k127_5243595_3	1150398.JIBJ01000008_gene667	3.135e-14	73.0	COG2128@1|root,COG2128@2|Bacteria,2IG23@201174|Actinobacteria,1W9IE@1268|Micrococcaceae	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD2_k127_5248338_1	1349820.M707_03540	1.84e-77	263.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_5248338_3	1449044.JMLE01000005_gene669	8.891e-63	216.0	2F5V4@1|root,33YE1@2|Bacteria,2IMSY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248338_6	134676.ACPL_1084	0.0004005	46.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD2_k127_5248338_0	290399.Arth_2662	3.114e-90	298.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,1W981@1268|Micrococcaceae	201174|Actinobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD2_k127_5248338_2	1077972.ARGLB_085_00800	1.432e-76	256.0	COG4942@1|root,COG4942@2|Bacteria,2GP1Y@201174|Actinobacteria,1W8TY@1268|Micrococcaceae	201174|Actinobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD2_k127_5251225_1	1101188.KI912156_gene4388	1.88e-84	282.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,1W7KG@1268|Micrococcaceae	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD2_k127_5251225_0	290399.Arth_0202	1.592e-196	619.0	COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,1W7JU@1268|Micrococcaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD2_k127_5251225_2	1150398.JIBJ01000002_gene1245	9.445e-70	238.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,1W7YK@1268|Micrococcaceae	201174|Actinobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HKD2_k127_5253312_1	1150398.JIBJ01000002_gene1181	5.395e-46	167.0	COG1215@1|root,COG1215@2|Bacteria,2IHNF@201174|Actinobacteria,1WBHX@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD2_k127_5253312_0	290399.Arth_0338	0.0	1142.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,1WAZ3@1268|Micrococcaceae	201174|Actinobacteria	P	Cation transporting ATPase, C-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD2_k127_5254193_1	1150398.JIBJ01000009_gene462	6.704e-58	202.0	COG0259@1|root,COG0259@2|Bacteria,2GKP3@201174|Actinobacteria,1WBFY@1268|Micrococcaceae	201174|Actinobacteria	H	Pfam:PNPOx_C	pdxH_1	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
HKD2_k127_5254193_0	290399.Arth_1503	2.407e-287	889.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,1W7IJ@1268|Micrococcaceae	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HKD2_k127_5254193_2	290399.Arth_1502	4.383e-36	136.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,1W8DZ@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
HKD2_k127_5263522_0	1150398.JIBJ01000018_gene2229	3.554e-176	556.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,1W8B0@1268|Micrococcaceae	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD2_k127_5263522_1	290399.Arth_0778	1.38e-55	198.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD2_k127_5264802_6	1151119.KB895522_gene2560	6.699e-08	59.0	COG2321@1|root,COG2321@2|Bacteria,2H3UT@201174|Actinobacteria,1W890@1268|Micrococcaceae	201174|Actinobacteria	S	Putative neutral zinc metallopeptidase	ypfJ	GO:0005575,GO:0005576	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
HKD2_k127_5264802_0	1150398.JIBJ01000004_gene3054	3.104e-217	683.0	COG0318@1|root,COG0318@2|Bacteria,2I908@201174|Actinobacteria,1W8UB@1268|Micrococcaceae	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5264802_2	290399.Arth_2110	6.921e-168	541.0	COG0183@1|root,COG0183@2|Bacteria,2GM29@201174|Actinobacteria,1WAEC@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the thiolase family	yhfS	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_5264802_4	1150398.JIBJ01000013_gene2590	1.924e-91	307.0	COG0619@1|root,COG0619@2|Bacteria,2IQMQ@201174|Actinobacteria,1W9JS@1268|Micrococcaceae	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16783	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25.1	-	-	CbiQ
HKD2_k127_5264802_3	1150398.JIBJ01000013_gene2589	3.87e-96	332.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,1W90I@1268|Micrococcaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	bioM	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
HKD2_k127_5264802_5	1150398.JIBJ01000013_gene2588	8.359e-86	290.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,1W985@1268|Micrococcaceae	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HKD2_k127_5264802_1	930171.Asphe3_18410	4.832e-170	535.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,1W7TX@1268|Micrococcaceae	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
HKD2_k127_5282125_1	1158050.KB895452_gene99	7.514e-123	394.0	COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,2GNMT@201174|Actinobacteria,1W98B@1268|Micrococcaceae	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD2_k127_5282125_0	1150398.JIBJ01000015_gene1956	8.208e-259	811.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,1W7ND@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HKD2_k127_5282125_2	1150398.JIBJ01000015_gene1955	6.295e-82	293.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,1W8C1@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
HKD2_k127_5288375_0	290399.Arth_3930	8.823e-146	465.0	COG2755@1|root,COG2755@2|Bacteria,2IBVP@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_5288375_3	290399.Arth_3929	9.768e-47	174.0	COG2350@1|root,COG2350@2|Bacteria,2GRVC@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD2_k127_5288375_2	1150398.JIBJ01000007_gene54	5.78e-87	289.0	COG1846@1|root,COG1846@2|Bacteria,2GMV1@201174|Actinobacteria,1W962@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_5288375_1	1150398.JIBJ01000007_gene53	4.177e-141	449.0	COG2755@1|root,COG2755@2|Bacteria,2GNBP@201174|Actinobacteria,1W86F@1268|Micrococcaceae	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_529597_2	1150398.JIBJ01000002_gene1241	5.974e-48	171.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,1W7H8@1268|Micrococcaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HKD2_k127_529597_0	290399.Arth_0204	4.889e-208	649.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,1W8AH@1268|Micrococcaceae	201174|Actinobacteria	P	Phosphate transport system permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD2_k127_529597_1	1449044.JMLE01000006_gene1113	2.968e-110	357.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,1W7KG@1268|Micrococcaceae	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD2_k127_5299857_0	1499967.BAYZ01000110_gene3008	5.007e-56	211.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,rve,rve_3
HKD2_k127_5300594_0	1150398.JIBJ01000019_gene873	0.0	1439.0	COG0841@1|root,COG0841@2|Bacteria,2GMQX@201174|Actinobacteria,1W82T@1268|Micrococcaceae	201174|Actinobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD2_k127_5300594_1	1150398.JIBJ01000015_gene1944	8.55e-63	218.0	COG0477@1|root,COG0477@2|Bacteria,2GKQH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_5303072_1	1150398.JIBJ01000011_gene2358	2.393e-98	321.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,1W7QK@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD2_k127_5303072_0	1150398.JIBJ01000011_gene2359	1.341e-219	684.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,1W7FY@1268|Micrococcaceae	201174|Actinobacteria	E	Aminotransferase	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HKD2_k127_5308637_2	1077972.ARGLB_016_00250	3.751e-53	189.0	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria,1W9UG@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD2_k127_5308637_0	290399.Arth_1485	2.643e-202	636.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,1W8Q9@1268|Micrococcaceae	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD2_k127_5308637_1	1449044.JMLE01000020_gene1867	8.669e-80	270.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,1W9YJ@1268|Micrococcaceae	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
HKD2_k127_5314423_1	494419.ALPM01000079_gene1987	1.31e-194	612.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,1W7FV@1268|Micrococcaceae	201174|Actinobacteria	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HKD2_k127_5314423_4	465541.ATCJ01000004_gene7507	1.39e-35	151.0	2E5NA@1|root,330D3@2|Bacteria,2IQ91@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
HKD2_k127_5314423_2	1349820.M707_19525	3.235e-116	380.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,1W8BB@1268|Micrococcaceae	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD2_k127_5314423_5	1150398.JIBJ01000015_gene1972	3.531e-20	100.0	COG2149@1|root,COG2149@2|Bacteria,2GWSM@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
HKD2_k127_5314423_3	595593.JREV01000021_gene1772	5.641e-46	170.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
HKD2_k127_5314423_0	1151119.KB895502_gene2989	2.703e-267	831.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria	201174|Actinobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
HKD2_k127_5323194_2	1101188.KI912155_gene2080	8.08e-58	205.0	COG3832@1|root,COG3832@2|Bacteria,2IIF0@201174|Actinobacteria	201174|Actinobacteria	J	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD2_k127_5323194_1	1449044.JMLE01000004_gene2474	1.297e-93	311.0	COG0640@1|root,COG0640@2|Bacteria,2IKVA@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HKD2_k127_5323194_0	1150398.JIBJ01000024_gene3914	4.322e-137	446.0	COG0477@1|root,COG2814@2|Bacteria,2IA1T@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_5326016_4	290399.Arth_3261	6.346e-34	137.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Laminin_G_3,Trypsin,fn3
HKD2_k127_5326016_1	1150398.JIBJ01000005_gene3097	1.423e-93	319.0	COG2365@1|root,COG2365@2|Bacteria,2IR8R@201174|Actinobacteria,1W9RM@1268|Micrococcaceae	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
HKD2_k127_5326016_0	1449044.JMLE01000004_gene2573	2.476e-113	367.0	COG1670@1|root,COG1670@2|Bacteria,2I90W@201174|Actinobacteria,1WC14@1268|Micrococcaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD2_k127_5326016_2	290399.Arth_3265	8.463e-59	207.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria	201174|Actinobacteria	E	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HKD2_k127_5326016_3	452863.Achl_3061	1.437e-50	179.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,1W8IV@1268|Micrococcaceae	201174|Actinobacteria	I	Dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD2_k127_5339628_0	1150398.JIBJ01000004_gene2854	4.175e-303	929.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,1W7JR@1268|Micrococcaceae	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD2_k127_5339628_1	1150398.JIBJ01000004_gene2855	2.338e-74	255.0	2DT7K@1|root,33J1V@2|Bacteria,2GTSK@201174|Actinobacteria,1W9SN@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1
HKD2_k127_5344864_2	290399.Arth_3345	6.924e-113	366.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,1W7JP@1268|Micrococcaceae	201174|Actinobacteria	BQ	acetoin utilization protein	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
HKD2_k127_5344864_0	290399.Arth_3346	9.008e-266	823.0	COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria,1W807@1268|Micrococcaceae	201174|Actinobacteria	P	Cation transport protein	trkB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HKD2_k127_5344864_1	1150398.JIBJ01000024_gene3906	2.986e-128	413.0	COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria,1W7PH@1268|Micrococcaceae	201174|Actinobacteria	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD2_k127_5344864_3	1449044.JMLE01000008_gene2120	3.048e-67	229.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
HKD2_k127_5362430_1	1151118.KB895787_gene1371	3.019e-12	67.0	COG4148@1|root,COG4148@2|Bacteria,2I34H@201174|Actinobacteria,1W9P1@1268|Micrococcaceae	201174|Actinobacteria	P	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
HKD2_k127_5362430_0	290340.AAur_3537	9.542e-225	704.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,1W7WG@1268|Micrococcaceae	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
HKD2_k127_5364325_0	290399.Arth_3378	0.0	1049.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,1W8HI@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD2_k127_5364325_1	1206730.BAGA01000109_gene5587	0.0002769	49.0	COG3832@1|root,COG3832@2|Bacteria,2ISYE@201174|Actinobacteria,4G9A8@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HKD2_k127_5371246_6	1077972.ARGLB_098_00310	6.339e-90	299.0	COG4147@1|root,COG4147@2|Bacteria,2GM3H@201174|Actinobacteria,1W8K6@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
HKD2_k127_5371246_5	290399.Arth_1372	9.964e-98	321.0	COG3599@1|root,COG3599@2|Bacteria,2GTPA@201174|Actinobacteria,1W9PV@1268|Micrococcaceae	201174|Actinobacteria	D	DivIVA domain repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5371246_1	290399.Arth_1371	3.209e-153	499.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,1W92E@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HKD2_k127_5371246_4	1449044.JMLE01000023_gene161	6.446e-105	342.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,1W8X2@1268|Micrococcaceae	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD2_k127_5371246_2	290340.AAur_1505	2.176e-150	479.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,1W7PZ@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD2_k127_5371246_0	930171.Asphe3_13580	3.958e-156	497.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,1W7J7@1268|Micrococcaceae	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD2_k127_5371246_3	1150398.JIBJ01000009_gene320	1.955e-141	451.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,1W7PE@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HKD2_k127_5375249_0	105425.BBPL01000102_gene1194	1.135e-170	552.0	COG3385@1|root,COG3385@2|Bacteria,2GKQB@201174|Actinobacteria,2NGZJ@228398|Streptacidiphilus	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
HKD2_k127_5375249_1	298653.Franean1_0474	6.58e-130	444.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve_3
HKD2_k127_5376095_2	1150398.JIBJ01000003_gene1890	3.763e-45	163.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,1W7HA@1268|Micrococcaceae	201174|Actinobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HKD2_k127_5376095_1	1150398.JIBJ01000003_gene1889	1.049e-100	330.0	2EEJD@1|root,338DD@2|Bacteria,2GVE2@201174|Actinobacteria,1WA0V@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5376095_0	290399.Arth_1649	1.531e-161	517.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,1W8BT@1268|Micrococcaceae	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
HKD2_k127_5380093_1	290399.Arth_1132	6.041e-110	356.0	COG0836@1|root,COG0836@2|Bacteria,2GIRM@201174|Actinobacteria,1W7I1@1268|Micrococcaceae	201174|Actinobacteria	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HKD2_k127_5380093_0	1158050.KB895456_gene1952	1.849e-247	765.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,1W7X1@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase family M20/M25/M40	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD2_k127_5380093_2	1150398.JIBJ01000006_gene3625	3.061e-37	141.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,1W9PB@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_5382232_2	1349820.M707_20175	9.229e-17	79.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,1W87E@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD2_k127_5382232_0	1077972.ARGLB_016_00120	3.982e-227	709.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,1W82I@1268|Micrococcaceae	201174|Actinobacteria	E	acetylornithine	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD2_k127_5382232_1	1349820.M707_20165	4.968e-46	177.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,1W82H@1268|Micrococcaceae	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD2_k127_5386182_0	1150398.JIBJ01000005_gene3226	6.155e-141	456.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,1WAQ5@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
HKD2_k127_5386182_1	1150398.JIBJ01000005_gene3225	4.579e-138	441.0	COG0477@1|root,COG2814@2|Bacteria,2GMBQ@201174|Actinobacteria,1WC3A@1268|Micrococcaceae	201174|Actinobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_5396309_1	886293.Sinac_3270	2.452e-06	51.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5396309_0	1210884.HG799470_gene14318	4.253e-74	266.0	COG5659@1|root,COG5659@2|Bacteria,2IWRG@203682|Planctomycetes	203682|Planctomycetes	L	best DB hits BLAST gb AAD45539.1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_54151_1	380394.Lferr_1829	1.48e-61	215.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,1SMIH@1236|Gammaproteobacteria,2NDMU@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
HKD2_k127_54151_0	1301098.PKB_3068	2.438e-121	403.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,1MVPR@1224|Proteobacteria,1RRTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	estB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD2_k127_5424067_0	1150398.JIBJ01000017_gene1414	4.691e-155	491.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,1W7ST@1268|Micrococcaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD2_k127_5424067_1	1150398.JIBJ01000017_gene1413	7.299e-128	411.0	COG0596@1|root,COG0596@2|Bacteria,2IDI0@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HKD2_k127_5424067_2	1349820.M707_02260	7.474e-10	66.0	COG1228@1|root,COG1228@2|Bacteria,2GKRZ@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD2_k127_5431775_1	1150398.JIBJ01000019_gene861	5.663e-29	123.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
HKD2_k127_5431775_0	1150398.JIBJ01000001_gene1383	4.053e-120	395.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_5438008_7	288705.RSal33209_3528	3.677e-08	55.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1WAIS@1268|Micrococcaceae	201174|Actinobacteria	EGP	transporter	-	-	-	ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2	-	-	MFS_1,Sugar_tr
HKD2_k127_5438008_6	290399.Arth_4121	1.042e-94	317.0	COG4291@1|root,COG4291@2|Bacteria,2IIVD@201174|Actinobacteria,1WBYE@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
HKD2_k127_5438008_1	1150398.JIBJ01000007_gene207	3.056e-256	796.0	COG1362@1|root,COG1362@2|Bacteria,2GKW4@201174|Actinobacteria,1W82Z@1268|Micrococcaceae	201174|Actinobacteria	E	M18 family aminopeptidase	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
HKD2_k127_5438008_0	1151119.KB895493_gene1479	7.918e-262	811.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,1W7WF@1268|Micrococcaceae	201174|Actinobacteria	E	amino acid	gabP	-	-	ko:K11735,ko:K16237	-	-	-	-	ko00000,ko02000	2.A.3.1.12,2.A.3.1.4,2.A.3.1.5	-	-	AA_permease
HKD2_k127_5438008_5	1151119.KB895493_gene1480	4.447e-104	346.0	COG1277@1|root,COG1277@2|Bacteria,2GMJD@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HKD2_k127_5438008_3	1150398.JIBJ01000007_gene213	6.732e-166	526.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,1W8JE@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_5438008_2	1150398.JIBJ01000007_gene214	1.584e-253	788.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GM2U@201174|Actinobacteria,1WB0E@1268|Micrococcaceae	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	bmrU	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
HKD2_k127_5438008_4	1150398.JIBJ01000007_gene215	9.819e-118	383.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,1W8F6@1268|Micrococcaceae	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_5440693_0	1150398.JIBJ01000007_gene173	2.197e-162	514.0	COG1082@1|root,COG3185@1|root,COG1082@2|Bacteria,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria,1W7S5@1268|Micrococcaceae	201174|Actinobacteria	EG	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AP_endonuc_2,Glyoxalase,Glyoxalase_5
HKD2_k127_5440693_1	1150398.JIBJ01000007_gene172	1.193e-149	476.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,1W7QP@1268|Micrococcaceae	201174|Actinobacteria	Q	protocatechuate 3,4-dioxygenase	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
HKD2_k127_5447462_2	882086.SacxiDRAFT_2349	4.052e-08	54.0	29WM0@1|root,30I7P@2|Bacteria,2HRZT@201174|Actinobacteria,4EBJQ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
HKD2_k127_5447462_0	211114.JOEF01000062_gene1836	2.253e-157	498.0	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria,4DZS4@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Peptidase_S9
HKD2_k127_5447462_1	1206725.BAFU01000053_gene1758	2.176e-129	416.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4FUI5@85025|Nocardiaceae	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
HKD2_k127_5452933_0	1150398.JIBJ01000007_gene63	0.0	1540.0	COG4913@1|root,COG4913@2|Bacteria,2GMIP@201174|Actinobacteria,1W7Z6@1268|Micrococcaceae	201174|Actinobacteria	S	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
HKD2_k127_5452933_1	1150398.JIBJ01000007_gene62	3.78e-54	191.0	2AS54@1|root,31HHY@2|Bacteria,2IAIN@201174|Actinobacteria,1W9D7@1268|Micrococcaceae	201174|Actinobacteria	S	FBP C-terminal treble-clef zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	FBP_C
HKD2_k127_5470894_2	1150398.JIBJ01000003_gene1877	5.233e-50	178.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,1W8M0@1268|Micrococcaceae	201174|Actinobacteria	E	Threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD2_k127_5470894_1	1150398.JIBJ01000003_gene1878	5.728e-113	368.0	2AIF4@1|root,318WM@2|Bacteria,2GK8R@201174|Actinobacteria,1W8XI@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
HKD2_k127_5470894_0	1150398.JIBJ01000003_gene1879	4.429e-254	787.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,1W8GE@1268|Micrococcaceae	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
HKD2_k127_5472123_2	1077972.ARGLB_043_00130	7.538e-78	261.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,1W7FN@1268|Micrococcaceae	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD2_k127_5472123_1	1150398.JIBJ01000006_gene3542	5.836e-89	301.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,1W8Y3@1268|Micrococcaceae	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HKD2_k127_5472123_0	1150398.JIBJ01000006_gene3541	5.933e-112	362.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,1W7NW@1268|Micrococcaceae	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD2_k127_5472123_3	1150398.JIBJ01000006_gene3540	6.272e-55	199.0	COG2197@1|root,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HKD2_k127_5475904_1	290399.Arth_2722	2.111e-76	258.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,1WB7C@1268|Micrococcaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HKD2_k127_5475904_0	290399.Arth_2723	1.023e-210	657.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,1WB1Z@1268|Micrococcaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD2_k127_5475904_2	290399.Arth_2724	3.49e-55	193.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,1WB5K@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD2_k127_5498895_3	1349820.M707_11585	0.0004845	45.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,1W98E@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
HKD2_k127_5498895_0	1077972.ARGLB_098_00040	4.841e-243	752.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,1W81G@1268|Micrococcaceae	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
HKD2_k127_5498895_1	1077972.ARGLB_098_00050	3.098e-43	159.0	COG2350@1|root,COG2350@2|Bacteria,2GQTW@201174|Actinobacteria	201174|Actinobacteria	S	PFAM YCII-related	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
HKD2_k127_5498895_2	1150398.JIBJ01000009_gene354	2.859e-07	51.0	2E3HJ@1|root,32YG5@2|Bacteria,2GQV8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5502594_2	494419.ALPM01000063_gene2260	6.399e-109	357.0	COG0596@1|root,COG0596@2|Bacteria,2I2VI@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
HKD2_k127_5502594_0	1150398.JIBJ01000004_gene2899	2.006e-202	647.0	COG0438@1|root,COG0438@2|Bacteria,2GN9W@201174|Actinobacteria,1W7P7@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_5502594_1	1449044.JMLE01000001_gene3919	1.218e-140	459.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,1W91J@1268|Micrococcaceae	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
HKD2_k127_5502594_3	290399.Arth_2252	1.303e-105	344.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,1W8V3@1268|Micrococcaceae	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
HKD2_k127_550438_2	290399.Arth_3172	9.442e-09	61.0	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria,1W8RT@1268|Micrococcaceae	201174|Actinobacteria	D	Involved in chromosome	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
HKD2_k127_550438_1	1150398.JIBJ01000005_gene3141	5.361e-160	509.0	COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria,1W7ZK@1268|Micrococcaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	blaB	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_550438_0	1158050.KB895452_gene662	9.502e-179	569.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,1W7XA@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_5509151_2	290399.Arth_1536	2.725e-06	49.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,1W8ZE@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
HKD2_k127_5509151_1	1150398.JIBJ01000014_gene2403	1.095e-111	367.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,1WCB9@1268|Micrococcaceae	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD2_k127_5509151_0	1150398.JIBJ01000014_gene2404	2.416e-315	968.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,1W7HN@1268|Micrococcaceae	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
HKD2_k127_5514990_2	1150398.JIBJ01000010_gene480	4.693e-196	644.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,1W7TH@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
HKD2_k127_5514990_1	1150398.JIBJ01000010_gene479	7.917e-219	683.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,1W8SM@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
HKD2_k127_5514990_0	452863.Achl_2495	3.727e-222	697.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,1W7MZ@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HKD2_k127_5514990_3	1150398.JIBJ01000010_gene477	8.336e-159	505.0	COG1028@1|root,COG1028@2|Bacteria,2GJVU@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_5518334_0	290399.Arth_0771	1.794e-229	712.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,1W7MG@1268|Micrococcaceae	201174|Actinobacteria	V	Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
HKD2_k127_5518334_1	1150398.JIBJ01000018_gene2236	1.231e-178	563.0	COG2966@1|root,COG2966@2|Bacteria,2GJMC@201174|Actinobacteria,1W7N6@1268|Micrococcaceae	201174|Actinobacteria	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HKD2_k127_5549212_0	1158050.KB895462_gene3884	5.174e-220	685.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1W7UE@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_5549212_1	290399.Arth_1268	1.071e-159	505.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,1W8N1@1268|Micrococcaceae	201174|Actinobacteria	P	Major Facilitator Superfamily	narU	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	iNJ661.Rv0267	MFS_1
HKD2_k127_5559999_2	1150398.JIBJ01000013_gene2501	2.453e-33	143.0	2CJ1M@1|root,32XE8@2|Bacteria,2GVFV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5559999_0	1449044.JMLE01000001_gene3981	9.372e-50	180.0	COG3631@1|root,COG3631@2|Bacteria,2IMVY@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD2_k127_5559999_1	1150398.JIBJ01000013_gene2500	1.983e-40	153.0	COG0654@1|root,COG0654@2|Bacteria,2HT9P@201174|Actinobacteria,1WA08@1268|Micrococcaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HKD2_k127_5564189_4	1132441.KI519455_gene3468	8.33e-73	249.0	COG1216@1|root,COG1216@2|Bacteria,2I406@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_5564189_5	1132441.KI519455_gene3467	8.864e-71	249.0	COG3222@1|root,COG3222@2|Bacteria,2GN3B@201174|Actinobacteria,1WADJ@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
HKD2_k127_5564189_7	1132441.KI519455_gene3466	1.153e-61	220.0	COG2227@1|root,COG2227@2|Bacteria,2GJAQ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
HKD2_k127_5564189_2	1132441.KI519455_gene3463	1.312e-127	427.0	COG1216@1|root,COG1216@2|Bacteria,2H44J@201174|Actinobacteria,1WAUK@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
HKD2_k127_5564189_3	1132441.KI519455_gene3472	1.423e-91	310.0	COG0005@1|root,COG0005@2|Bacteria,2GKGG@201174|Actinobacteria,1WBPZ@1268|Micrococcaceae	201174|Actinobacteria	F	Phosphorylase superfamily	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HKD2_k127_5564189_1	1132441.KI519455_gene3471	9.466e-158	511.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,1W892@1268|Micrococcaceae	201174|Actinobacteria	M	GDP-mannose 4,6 dehydratase	wbiB	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD2_k127_5564189_8	1150399.AQYK01000002_gene3592	1.666e-13	79.0	2BIA9@1|root,32CFW@2|Bacteria,2GTQ5@201174|Actinobacteria,4FQGI@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5564189_0	1132441.KI519455_gene3464	2.474e-168	537.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,1WARB@1268|Micrococcaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
HKD2_k127_5564189_6	443906.CMM_0145	7.014e-69	241.0	2C254@1|root,2ZWPJ@2|Bacteria,2INBE@201174|Actinobacteria,4FSFE@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5583747_1	1077972.ARGLB_080_01040	1.283e-99	330.0	COG2852@1|root,COG2852@2|Bacteria,2GTCW@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
HKD2_k127_5583747_2	1158050.KB895452_gene612	6.223e-87	287.0	2ENAH@1|root,33FY7@2|Bacteria,2IRJG@201174|Actinobacteria,1W9SZ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5583747_0	1150398.JIBJ01000005_gene3160	8.626e-115	372.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,1W8YW@1268|Micrococcaceae	201174|Actinobacteria	S	UPF0126 domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0126
HKD2_k127_5602028_1	1150398.JIBJ01000004_gene2946	6.588e-133	426.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,1W7UY@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD2_k127_5602028_2	1449044.JMLE01000001_gene3954	6.397e-99	325.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,1W9EI@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
HKD2_k127_5602028_0	1150398.JIBJ01000004_gene2948	2.122e-260	816.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,1W89P@1268|Micrococcaceae	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD2_k127_5602028_3	1077972.ARGLB_039_01180	8.71e-70	237.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,1W965@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD2_k127_5606897_1	290399.Arth_4028	1.159e-126	407.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,1W804@1268|Micrococcaceae	201174|Actinobacteria	C	Pyruvate dehydrogenase	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD2_k127_5606897_0	290399.Arth_4027	9.437e-203	633.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,1W826@1268|Micrococcaceae	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD2_k127_5606897_2	1150398.JIBJ01000007_gene141	8.683e-69	239.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,1W7MS@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_5653726_0	1150398.JIBJ01000002_gene1067	1.669e-128	416.0	COG3707@1|root,COG3707@2|Bacteria,2IF8A@201174|Actinobacteria,1W9JA@1268|Micrococcaceae	201174|Actinobacteria	T	ANTAR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
HKD2_k127_5656498_0	543632.JOJL01000124_gene8439	1.613e-39	160.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4DD18@85008|Micromonosporales	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_5656498_1	998088.B565_2242	2.322e-14	74.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,1RRAM@1236|Gammaproteobacteria,1Y6DF@135624|Aeromonadales	135624|Aeromonadales	K	UTRA	-	-	-	ko:K11922	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
HKD2_k127_5660788_7	1150398.JIBJ01000004_gene2674	4.331e-14	72.0	2AH8W@1|root,317IZ@2|Bacteria,2HZ70@201174|Actinobacteria,1W9W5@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5660788_5	644283.Micau_2252	1.116e-53	204.0	COG3281@1|root,COG3281@2|Bacteria,2GPHW@201174|Actinobacteria,4DJH9@85008|Micromonosporales	201174|Actinobacteria	G	Trehalose synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5660788_6	1150398.JIBJ01000004_gene2930	8.635e-51	184.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD2_k127_5660788_3	1449044.JMLE01000001_gene3745	6.486e-91	306.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,1W95M@1268|Micrococcaceae	201174|Actinobacteria	O	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD2_k127_5660788_2	1150398.JIBJ01000004_gene2676	4.815e-100	334.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,1W9AP@1268|Micrococcaceae	201174|Actinobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HKD2_k127_5660788_0	1150398.JIBJ01000004_gene2677	4.648e-159	507.0	COG0451@1|root,COG0451@2|Bacteria,2GP01@201174|Actinobacteria,1WA44@1268|Micrococcaceae	201174|Actinobacteria	GM	NAD dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD2_k127_5660788_4	1150398.JIBJ01000004_gene2678	3.529e-80	269.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria,1WB7H@1268|Micrococcaceae	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
HKD2_k127_5660788_1	1150398.JIBJ01000004_gene2679	7.597e-126	406.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,1W7Z2@1268|Micrococcaceae	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
HKD2_k127_5665683_0	1150398.JIBJ01000005_gene3384	1.977e-283	872.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,1W7WK@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HKD2_k127_5665683_1	290399.Arth_2872	7.141e-89	295.0	COG1762@1|root,COG1762@2|Bacteria,2IMPP@201174|Actinobacteria,1WASX@1268|Micrococcaceae	201174|Actinobacteria	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	fruB	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
HKD2_k127_5665683_2	1449044.JMLE01000002_gene4310	1.3e-19	88.0	COG3346@1|root,COG3346@2|Bacteria,2GMGB@201174|Actinobacteria,1W995@1268|Micrococcaceae	201174|Actinobacteria	S	SURF1 family	-	-	-	-	-	-	-	-	-	-	-	-	SURF1
HKD2_k127_5672539_0	290399.Arth_1181	2.492e-120	387.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,1W7E8@1268|Micrococcaceae	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD2_k127_5672539_1	1151119.KB895495_gene2358	4.833e-64	224.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,1W9J1@1268|Micrococcaceae	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_5672539_2	290399.Arth_1177	5.612e-51	183.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,1W9Z7@1268|Micrococcaceae	201174|Actinobacteria	NOU	peptidase	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
HKD2_k127_56814_1	1150398.JIBJ01000010_gene492	1.203e-127	409.0	COG0847@1|root,COG0847@2|Bacteria,2I2KI@201174|Actinobacteria,1W8ZA@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase III	dnaQ2	-	2.7.7.7	ko:K02337,ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HKD2_k127_56814_2	1150398.JIBJ01000010_gene493	2.574e-57	209.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria,1WA7H@1268|Micrococcaceae	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
HKD2_k127_56814_0	1150398.JIBJ01000010_gene494	0.0	1103.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,1W8FJ@1268|Micrococcaceae	201174|Actinobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C
HKD2_k127_5745716_2	926569.ANT_08030	2.571e-11	67.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
HKD2_k127_5745716_1	1122138.AQUZ01000083_gene3524	1.34e-17	86.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4DUHR@85009|Propionibacteriales	201174|Actinobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_5745716_0	886293.Sinac_2162	9.681e-107	361.0	COG1570@1|root,COG1961@1|root,COG1570@2|Bacteria,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	xseA	-	3.1.11.6	ko:K03601,ko:K13582	ko03430,ko04112,map03430,map04112	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,KfrA_N,Recombinase,Resolvase,Zn_ribbon_recom,tRNA_anti_2
HKD2_k127_5746660_1	521674.Plim_1047	1.245e-94	325.0	COG3385@1|root,COG3385@2|Bacteria,2IYW8@203682|Planctomycetes	203682|Planctomycetes	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HKD2_k127_5746660_0	991905.SL003B_4075	2.331e-105	357.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria	1224|Proteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_38,HTH_7,rve
HKD2_k127_5746660_2	1123229.AUBC01000040_gene3836	2.382e-25	117.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TS16@28211|Alphaproteobacteria,3JSGF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
HKD2_k127_5768772_2	1101188.KI912155_gene2592	6.964e-08	54.0	COG1846@1|root,COG1846@2|Bacteria,2IK59@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_5768772_0	1101188.KI912155_gene2594	2.474e-165	524.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,1W89S@1268|Micrococcaceae	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
HKD2_k127_5768772_1	290399.Arth_3399	1.524e-39	152.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,1W7R8@1268|Micrococcaceae	201174|Actinobacteria	M	penicillin-binding protein	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
HKD2_k127_5788068_0	1089553.Tph_c08010	2.46e-76	271.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1TT8V@1239|Firmicutes,24BFH@186801|Clostridia,42ETS@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
HKD2_k127_5788068_1	1121028.ARQE01000007_gene3749	3.26e-14	74.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2TRJN@28211|Alphaproteobacteria,2PK7R@255475|Aurantimonadaceae	28211|Alphaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HKD2_k127_5800842_1	1299327.I546_0750	1.328e-48	178.0	2DXQ4@1|root,345YG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5800842_0	1299327.I546_0751	7.45e-146	475.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
HKD2_k127_5800842_2	1032480.MLP_18900	1.149e-45	167.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4DU8I@85009|Propionibacteriales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
HKD2_k127_5803650_3	1150398.JIBJ01000005_gene3071	1.077e-05	47.0	2EGDD@1|root,33A58@2|Bacteria,2GR3X@201174|Actinobacteria,1WA3P@1268|Micrococcaceae	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
HKD2_k127_5803650_2	1150398.JIBJ01000005_gene3072	2.643e-41	154.0	2DZ3S@1|root,34CBX@2|Bacteria,2GX0A@201174|Actinobacteria,1W9Y3@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4229
HKD2_k127_5803650_0	1449044.JMLE01000004_gene2552	7.889e-163	517.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,1W8AZ@1268|Micrococcaceae	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD2_k127_5803650_1	1150398.JIBJ01000005_gene3074	1.151e-108	356.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,1W7N2@1268|Micrococcaceae	201174|Actinobacteria	IQ	AMP-binding enzyme	menE	-	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5813836_3	1243664.CAVL020000061_gene3853	1.716e-08	58.0	29S0J@1|root,30D4W@2|Bacteria,1UAUR@1239|Firmicutes,4IM7J@91061|Bacilli,1ZJEQ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5813836_0	290399.Arth_2749	0.0	1770.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,1W7F6@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
HKD2_k127_5813836_1	1150398.JIBJ01000010_gene501	1.606e-171	553.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,1W85H@1268|Micrococcaceae	201174|Actinobacteria	T	Belongs to the peptidase S16 family	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
HKD2_k127_5813836_2	1150398.JIBJ01000010_gene500	3.219e-26	108.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,1W7XE@1268|Micrococcaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
HKD2_k127_5845041_3	1276920.ADIAG_02611	1.251e-13	71.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5845041_0	1273125.Rrhod_3359	1.636e-117	394.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4FYGY@85025|Nocardiaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD2_k127_5845041_1	1078020.KEK_03932	1.23e-57	214.0	COG1309@1|root,COG1309@2|Bacteria,2GNY5@201174|Actinobacteria,234VN@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	ethR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K21961	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
HKD2_k127_5845041_2	1211815.CBYP010000067_gene78	9.793e-53	188.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	ethA	-	-	ko:K10215	ko00627,ko01120,map00627,map01120	-	R07836,R07837	RC02100,RC03121	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,FMO-like,NAD_binding_8,Pyr_redox_2
HKD2_k127_5861890_0	1150398.JIBJ01000002_gene987	0.0	1013.0	COG2225@1|root,COG2225@2|Bacteria,2GJGP@201174|Actinobacteria,1W7W5@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
HKD2_k127_5871117_2	1150398.JIBJ01000005_gene3234	2.759e-48	178.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,1W8DH@1268|Micrococcaceae	201174|Actinobacteria	L	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD2_k127_5871117_0	1150398.JIBJ01000005_gene3233	5.092e-115	374.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria,1W9MH@1268|Micrococcaceae	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
HKD2_k127_5871117_1	1150398.JIBJ01000005_gene3232	6.131e-76	264.0	2EK75@1|root,33DXI@2|Bacteria,2GZ47@201174|Actinobacteria,1WBN1@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5871117_3	290399.Arth_3053	6.208e-34	132.0	COG0754@1|root,COG0754@2|Bacteria,2GMQ5@201174|Actinobacteria,1W7QW@1268|Micrococcaceae	201174|Actinobacteria	E	Glutathionylspermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
HKD2_k127_590101_1	930171.Asphe3_00570	2.372e-45	175.0	2DB9H@1|root,2Z7WW@2|Bacteria,2I2TQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
HKD2_k127_590101_0	1449044.JMLE01000035_gene440	1.963e-148	486.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	celR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HKD2_k127_590101_2	1449044.JMLE01000004_gene2582	4.478e-11	63.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,1W9BY@1268|Micrococcaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD2_k127_5905528_0	1150398.JIBJ01000004_gene2880	1.1e-140	447.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,1W7I0@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
HKD2_k127_5905528_1	1150398.JIBJ01000004_gene2881	2.57e-73	261.0	29762@1|root,2ZUDZ@2|Bacteria,2GXRB@201174|Actinobacteria,1WBMV@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
HKD2_k127_5905528_2	1449044.JMLE01000001_gene3902	6.706e-54	191.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,1W7FZ@1268|Micrococcaceae	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD2_k127_5931680_3	1150398.JIBJ01000015_gene1950	2.821e-12	73.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,1WARN@1268|Micrococcaceae	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD2_k127_5931680_1	1150398.JIBJ01000015_gene1951	6.557e-120	388.0	COG3358@1|root,COG3358@2|Bacteria,2GP66@201174|Actinobacteria,1WB7U@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
HKD2_k127_5931680_2	1150398.JIBJ01000015_gene1952	5.093e-75	257.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	GtrA
HKD2_k127_5931680_0	1150398.JIBJ01000015_gene1953	1.278e-139	449.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,1W7I6@1268|Micrococcaceae	201174|Actinobacteria	E	Aminotransferase class-V	iscS1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD2_k127_5954151_3	1158050.KB895466_gene3368	5.154e-72	244.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,1W8Z2@1268|Micrococcaceae	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
HKD2_k127_5954151_4	1449044.JMLE01000032_gene4554	3.154e-33	138.0	COG2501@1|root,COG2501@2|Bacteria,2GQG8@201174|Actinobacteria,1WA2A@1268|Micrococcaceae	201174|Actinobacteria	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
HKD2_k127_5954151_1	1150398.JIBJ01000006_gene3457	2.084e-160	510.0	COG3238@1|root,COG3238@2|Bacteria,2IB1U@201174|Actinobacteria,1W8XR@1268|Micrococcaceae	201174|Actinobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
HKD2_k127_5954151_0	1151119.KB895509_gene359	8.222e-308	945.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,1W8CY@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
HKD2_k127_5954151_2	290399.Arth_1331	8.131e-94	310.0	COG0454@1|root,COG0456@2|Bacteria,2IH4B@201174|Actinobacteria,1W8TX@1268|Micrococcaceae	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_5962434_1	1150398.JIBJ01000002_gene1205	4.684e-44	163.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,1W9UI@1268|Micrococcaceae	201174|Actinobacteria	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HKD2_k127_5962434_0	1151119.KB895492_gene1678	1.602e-286	882.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,1W7N3@1268|Micrococcaceae	201174|Actinobacteria	GT	PTS system, fructose-specific	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HKD2_k127_5982154_0	1449044.JMLE01000001_gene3915	2.54e-189	602.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,1W7NF@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD2_k127_5982154_3	1150398.JIBJ01000004_gene2895	5.631e-47	169.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,1W9QX@1268|Micrococcaceae	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
HKD2_k127_5982154_1	1150398.JIBJ01000004_gene2894	9.068e-114	368.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,1W8JJ@1268|Micrococcaceae	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HKD2_k127_5982154_4	1150398.JIBJ01000004_gene2893	1.316e-39	157.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,1W9UW@1268|Micrococcaceae	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5982154_2	452863.Achl_1998	3.949e-56	198.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,1W8FK@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD2_k127_6034291_0	1449044.JMLE01000027_gene1609	2.566e-176	560.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,1W7FE@1268|Micrococcaceae	201174|Actinobacteria	T	phosphatase	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HKD2_k127_6034291_2	1150398.JIBJ01000007_gene262	6.723e-90	301.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,1W93H@1268|Micrococcaceae	201174|Actinobacteria	T	Forkhead associated domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
HKD2_k127_6034291_1	1150398.JIBJ01000007_gene263	2.725e-121	393.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,1W8EC@1268|Micrococcaceae	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
HKD2_k127_6041575_0	1158050.KB895454_gene1431	1.439e-154	489.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,1W7I4@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HKD2_k127_6041575_1	1449044.JMLE01000001_gene3926	1.188e-151	487.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,1W8ZP@1268|Micrococcaceae	201174|Actinobacteria	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD2_k127_6041575_2	1449044.JMLE01000001_gene3929	4.499e-64	229.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,1W9R6@1268|Micrococcaceae	201174|Actinobacteria	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HKD2_k127_6041575_3	1077972.ARGLB_039_00920	1.329e-20	104.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,1W8GP@1268|Micrococcaceae	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HKD2_k127_6092889_1	290399.Arth_2360	2.159e-129	415.0	COG2230@1|root,COG2230@2|Bacteria,2GM5H@201174|Actinobacteria	201174|Actinobacteria	M	synthase	ufaA1	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
HKD2_k127_6092889_0	290399.Arth_2359	5.33e-212	667.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
HKD2_k127_614418_0	1150398.JIBJ01000001_gene1393	1.574e-140	449.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,1W82Y@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
HKD2_k127_614418_2	290399.Arth_0680	4.946e-84	283.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,1WAK3@1268|Micrococcaceae	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
HKD2_k127_614418_1	290399.Arth_0681	2.849e-109	357.0	COG1966@1|root,COG1966@2|Bacteria,2GIYX@201174|Actinobacteria,1W8N6@1268|Micrococcaceae	201174|Actinobacteria	T	Carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
HKD2_k127_6177825_1	909663.KI867150_gene2709	1.07e-11	69.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42R4P@68525|delta/epsilon subdivisions,2X5AT@28221|Deltaproteobacteria,2MQF9@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
HKD2_k127_6177825_0	909663.KI867150_gene2708	2.301e-145	471.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42T20@68525|delta/epsilon subdivisions,2WP7S@28221|Deltaproteobacteria,2MQGC@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Integrase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
HKD2_k127_6177825_2	864069.MicloDRAFT_00010690	6.792e-06	48.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2TQPC@28211|Alphaproteobacteria,1JXET@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
HKD2_k127_6221701_2	290399.Arth_1976	6.317e-65	227.0	COG3476@1|root,COG3476@2|Bacteria,2I3NJ@201174|Actinobacteria,1WA10@1268|Micrococcaceae	201174|Actinobacteria	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
HKD2_k127_6221701_1	1449044.JMLE01000004_gene2592	5.193e-77	266.0	COG3707@1|root,COG3707@2|Bacteria,2I8E6@201174|Actinobacteria	201174|Actinobacteria	K	Antar domain	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,PAS_3
HKD2_k127_6221701_0	1150398.JIBJ01000022_gene3763	1.197e-108	357.0	COG1309@1|root,COG1309@2|Bacteria,2GQRD@201174|Actinobacteria,1WBVH@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
HKD2_k127_6224463_2	1150398.JIBJ01000013_gene2501	5.591e-25	104.0	2CJ1M@1|root,32XE8@2|Bacteria,2GVFV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6224463_1	1150398.JIBJ01000013_gene2502	1.393e-97	323.0	COG0242@1|root,COG0242@2|Bacteria,2GNZ9@201174|Actinobacteria,1W9CR@1268|Micrococcaceae	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD2_k127_6224463_0	290399.Arth_2192	2.5e-323	1001.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,1W8NG@1268|Micrococcaceae	201174|Actinobacteria	EU	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD2_k127_6239601_1	1150398.JIBJ01000006_gene3660	1.583e-23	107.0	2DCUI@1|root,2ZFDT@2|Bacteria,2GY7T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6239601_0	290399.Arth_1096	7.31e-170	548.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria,1W9CQ@1268|Micrococcaceae	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HKD2_k127_6288033_0	1123319.AUBE01000036_gene2449	5.37e-80	274.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
HKD2_k127_6288033_1	358823.DF19_29580	6.078e-73	250.0	COG3415@1|root,COG3415@2|Bacteria,2IHIM@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_33
HKD2_k127_6288033_2	101510.RHA1_ro01667	1.006e-10	62.0	COG3293@1|root,COG3293@2|Bacteria,2IIB4@201174|Actinobacteria,4G2PD@85025|Nocardiaceae	201174|Actinobacteria	L	transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
HKD2_k127_62941_2	1115632.JAFW01000001_gene833	3.157e-98	325.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria	201174|Actinobacteria	U	UPF0056 membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
HKD2_k127_62941_1	452863.Achl_2507	1.085e-155	494.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,1W8C3@1268|Micrococcaceae	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
HKD2_k127_62941_0	1150398.JIBJ01000011_gene2336	2.455e-183	575.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,1W83T@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD2_k127_632598_1	886293.Sinac_5034	1.141e-39	151.0	COG2365@1|root,COG2365@2|Bacteria,2J1CF@203682|Planctomycetes	203682|Planctomycetes	T	Protein tyrosine serine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
HKD2_k127_632598_0	1210884.HG799466_gene12525	5.57e-44	169.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_632598_2	1429046.RR21198_5554	8.026e-28	119.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4G4Z5@85025|Nocardiaceae	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_632598_3	1123024.AUII01000011_gene4401	2.101e-09	68.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4EAVH@85010|Pseudonocardiales	201174|Actinobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_6331546_2	930171.Asphe3_15130	1.488e-132	425.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,1W7QR@1268|Micrococcaceae	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD2_k127_6331546_4	1197706.AKKK01000066_gene3656	5.213e-96	331.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,1W99J@1268|Micrococcaceae	201174|Actinobacteria	K	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD2_k127_6331546_1	1449044.JMLE01000017_gene1339	3.881e-204	644.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,1W7DV@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD2_k127_6331546_0	1150398.JIBJ01000014_gene2401	1.949e-204	657.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,1W87D@1268|Micrococcaceae	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
HKD2_k127_6331546_3	1150398.JIBJ01000014_gene2402	2.575e-105	366.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,1W8ZE@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
HKD2_k127_636366_5	1150398.JIBJ01000015_gene1976	3.743e-118	382.0	COG0847@1|root,COG0847@2|Bacteria,2IIG4@201174|Actinobacteria,1W7WS@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T
HKD2_k127_636366_8	1151061.CAJY01000028_gene880	9.467e-49	180.0	2DMC7@1|root,32J0V@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
HKD2_k127_636366_7	1150398.JIBJ01000015_gene1974	7.197e-97	336.0	COG1397@1|root,COG1397@2|Bacteria,2GKHI@201174|Actinobacteria,1W8U8@1268|Micrococcaceae	201174|Actinobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HKD2_k127_636366_6	1150398.JIBJ01000015_gene1971	1.157e-109	365.0	COG0580@1|root,COG0580@2|Bacteria,2IF7U@201174|Actinobacteria,1W9MF@1268|Micrococcaceae	201174|Actinobacteria	G	Major intrinsic protein	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
HKD2_k127_636366_2	1150398.JIBJ01000015_gene1970	7.213e-204	639.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,1W857@1268|Micrococcaceae	201174|Actinobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HKD2_k127_636366_0	1449044.JMLE01000005_gene570	0.0	1172.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,1W8AG@1268|Micrococcaceae	201174|Actinobacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
HKD2_k127_636366_3	1449044.JMLE01000005_gene569	3.008e-167	538.0	COG0477@1|root,COG2814@2|Bacteria,2GMHP@201174|Actinobacteria,1W9KU@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_636366_4	1150398.JIBJ01000015_gene1967	1.946e-120	389.0	COG1414@1|root,COG1414@2|Bacteria,2GMEA@201174|Actinobacteria,1W9AB@1268|Micrococcaceae	201174|Actinobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_636366_1	1150398.JIBJ01000015_gene1964	1.742e-268	831.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1W80G@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_636366_9	452863.Achl_3766	4.767e-14	79.0	COG3103@1|root,COG3103@2|Bacteria,2IGZN@201174|Actinobacteria,1WA9S@1268|Micrococcaceae	201174|Actinobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6388987_0	981369.JQMJ01000001_gene6656	1.445e-164	527.0	COG1609@1|root,COG1609@2|Bacteria,2GK7G@201174|Actinobacteria,2NKXB@228398|Streptacidiphilus	201174|Actinobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
HKD2_k127_6399775_2	1150398.JIBJ01000026_gene34	3.229e-56	211.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,2GMX8@201174|Actinobacteria,1W8PR@1268|Micrococcaceae	201174|Actinobacteria	L	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_12,AAA_30,RNase_H_2
HKD2_k127_6399775_1	1150398.JIBJ01000026_gene33	9.835e-85	293.0	COG3449@1|root,COG3449@2|Bacteria,2IHU0@201174|Actinobacteria,1WBEB@1268|Micrococcaceae	201174|Actinobacteria	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
HKD2_k127_6399775_0	1150398.JIBJ01000026_gene32	5.884e-186	586.0	COG2183@1|root,COG2183@2|Bacteria,2GKCI@201174|Actinobacteria,1WAQZ@1268|Micrococcaceae	201174|Actinobacteria	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HKD2_k127_6399915_0	930171.Asphe3_27280	1.245e-189	593.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,1W7MT@1268|Micrococcaceae	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD2_k127_6399915_1	1150398.JIBJ01000005_gene3375	6.674e-53	187.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,1W9GN@1268|Micrococcaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD2_k127_6399915_3	1158050.KB895452_gene401	7.774e-09	56.0	COG2265@1|root,COG2265@2|Bacteria,2GK97@201174|Actinobacteria,1W7T4@1268|Micrococcaceae	201174|Actinobacteria	J	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_15,Methyltransf_25
HKD2_k127_6401612_0	1150398.JIBJ01000005_gene3174	1.579e-115	377.0	2DBB1@1|root,2Z854@2|Bacteria,2GNBN@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
HKD2_k127_6401612_1	1150398.JIBJ01000005_gene3175	1.094e-89	298.0	2C7GR@1|root,32H51@2|Bacteria,2IPDA@201174|Actinobacteria,1WC70@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6401612_2	1150398.JIBJ01000005_gene3180	4.925e-29	115.0	COG3835@1|root,COG3835@2|Bacteria,2IH74@201174|Actinobacteria,1W8PY@1268|Micrococcaceae	201174|Actinobacteria	KT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
HKD2_k127_6409223_0	222534.KB893755_gene4259	1.203e-196	616.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4ERIG@85013|Frankiales	201174|Actinobacteria	L	PFAM Transposase, Mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HKD2_k127_6409223_2	1380393.JHVP01000004_gene401	1.12e-22	109.0	COG5416@1|root,COG5416@2|Bacteria,2HD5K@201174|Actinobacteria	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
HKD2_k127_6409223_1	574375.BAGA_09620	3.677e-72	248.0	COG1961@1|root,COG1961@2|Bacteria,1UZT3@1239|Firmicutes,4HCR8@91061|Bacilli,1ZQD4@1386|Bacillus	91061|Bacilli	L	Resolvase, N terminal domain	binR	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
HKD2_k127_6409650_0	1150398.JIBJ01000002_gene981	1.765e-210	657.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1WAIS@1268|Micrococcaceae	201174|Actinobacteria	EGP	transporter	kgtP	-	-	ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2	-	-	MFS_1,Sugar_tr
HKD2_k127_6409650_1	290399.Arth_0593	5.956e-158	501.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,1W8RX@1268|Micrococcaceae	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HKD2_k127_6425022_0	886293.Sinac_2157	9.563e-220	689.0	COG3385@1|root,COG3385@2|Bacteria,2J0KK@203682|Planctomycetes	203682|Planctomycetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_6425022_1	290317.Cpha266_0332	4.201e-56	202.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
HKD2_k127_6425545_0	1150398.JIBJ01000002_gene1197	1.36e-209	661.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,1W8UT@1268|Micrococcaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
HKD2_k127_6425545_1	1150398.JIBJ01000002_gene1198	1.499e-57	201.0	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria,1WCEB@1268|Micrococcaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
HKD2_k127_6427771_4	1150398.JIBJ01000005_gene3139	7.927e-55	210.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,1W7XA@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_6427771_1	1150398.JIBJ01000005_gene3138	9.998e-220	689.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,1W7IV@1268|Micrococcaceae	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD2_k127_6427771_0	1150398.JIBJ01000005_gene3137	9.468e-230	715.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,1W8FX@1268|Micrococcaceae	201174|Actinobacteria	C	Pyruvate dehydrogenase	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD2_k127_6427771_3	1150398.JIBJ01000005_gene3136	2.848e-86	286.0	COG1522@1|root,COG1522@2|Bacteria,2HVG9@201174|Actinobacteria,1W9CY@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD2_k127_6427771_2	1150398.JIBJ01000005_gene3134	8.834e-104	338.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,1W827@1268|Micrococcaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	paaG	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD2_k127_6432462_0	1341151.ASZU01000003_gene2371	3.673e-19	100.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,27D2T@186824|Thermoactinomycetaceae	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_6433716_4	909613.UO65_4379	3.507e-14	72.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_6433716_3	103733.JNYO01000001_gene295	1.186e-16	91.0	2E9GJ@1|root,333PP@2|Bacteria,2HC60@201174|Actinobacteria,4DXR0@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
HKD2_k127_6433716_1	1123251.ATWM01000001_gene908	3.519e-25	108.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	isaA	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	LysM,SLT,Transglycosylas
HKD2_k127_6433716_0	1380356.JNIK01000006_gene1437	4.251e-58	211.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4EURQ@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
HKD2_k127_6433716_2	477641.MODMU_3377	2.456e-17	81.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4ESIH@85013|Frankiales	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
HKD2_k127_6435144_2	1150398.JIBJ01000009_gene452	2.783e-94	314.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,1W8P6@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qorA	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_6435144_0	1150398.JIBJ01000009_gene454	2.405e-200	626.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,1W82P@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD2_k127_6435144_1	1449044.JMLE01000020_gene1856	4.427e-186	585.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,1W87V@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HKD2_k127_6458652_0	1101188.KI912155_gene3582	1.076e-123	401.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,1W9AA@1268|Micrococcaceae	201174|Actinobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
HKD2_k127_6458652_2	710696.Intca_0271	3.694e-88	310.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4FG0T@85021|Intrasporangiaceae	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
HKD2_k127_6458652_1	1449044.JMLE01000041_gene1786	2.105e-98	326.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
HKD2_k127_6458652_3	1150398.JIBJ01000004_gene3015	1.136e-39	149.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,1W7JM@1268|Micrococcaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
HKD2_k127_6466049_0	1150398.JIBJ01000002_gene939	3.309e-143	456.0	COG0564@1|root,COG0564@2|Bacteria,2GJ2Z@201174|Actinobacteria,1W864@1268|Micrococcaceae	201174|Actinobacteria	J	synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD2_k127_6466049_1	1150398.JIBJ01000002_gene940	1.025e-105	346.0	COG0586@1|root,COG0586@2|Bacteria,2ID8E@201174|Actinobacteria	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD2_k127_6466049_2	1150398.JIBJ01000002_gene941	1.318e-49	177.0	2EKUG@1|root,33EI5@2|Bacteria,2GTFS@201174|Actinobacteria,1WA0C@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6472803_8	1101188.KI912155_gene2592	1.959e-63	221.0	COG1846@1|root,COG1846@2|Bacteria,2IK59@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_6472803_10	1449044.JMLE01000025_gene3325	1.589e-44	163.0	COG1550@1|root,COG1550@2|Bacteria,2IQW4@201174|Actinobacteria,1WA43@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
HKD2_k127_6472803_9	290399.Arth_0538	3.701e-60	209.0	COG1359@1|root,COG1359@2|Bacteria,2IQ6Y@201174|Actinobacteria,1W9Q9@1268|Micrococcaceae	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD2_k127_6472803_5	1150398.JIBJ01000002_gene1039	5.938e-107	349.0	COG0457@1|root,COG0457@2|Bacteria,2IRQN@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_4
HKD2_k127_6472803_7	290399.Arth_0536	1.269e-66	240.0	COG4762@1|root,COG4762@2|Bacteria,2IQ4G@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1990
HKD2_k127_6472803_6	1449044.JMLE01000025_gene3329	4.219e-70	239.0	COG2315@1|root,COG2315@2|Bacteria,2IHRR@201174|Actinobacteria,1W9W9@1268|Micrococcaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
HKD2_k127_6472803_1	1150398.JIBJ01000002_gene1042	1.967e-209	657.0	COG1960@1|root,COG1960@2|Bacteria,2H7DI@201174|Actinobacteria,1W7T8@1268|Micrococcaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_6472803_2	1150398.JIBJ01000002_gene1043	2.965e-168	531.0	COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,1WCJU@1268|Micrococcaceae	201174|Actinobacteria	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD2_k127_6472803_0	1150398.JIBJ01000002_gene1044	2.254e-288	888.0	COG2141@1|root,COG2141@2|Bacteria,2GJAN@201174|Actinobacteria,1WAVI@1268|Micrococcaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_6472803_4	1150398.JIBJ01000002_gene1045	1.8e-118	383.0	COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,1W8QH@1268|Micrococcaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
HKD2_k127_6472803_3	1150398.JIBJ01000002_gene1046	1.274e-133	430.0	COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,1W8K4@1268|Micrococcaceae	201174|Actinobacteria	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
HKD2_k127_6482904_0	1150398.JIBJ01000003_gene1880	5.238e-249	771.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,1WAF7@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_6482904_1	290399.Arth_1654	2.899e-28	128.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,1W7M8@1268|Micrococcaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HKD2_k127_6484023_0	1101188.KI912155_gene1074	2.26e-166	526.0	COG3396@1|root,COG3396@2|Bacteria,2GJIU@201174|Actinobacteria,1W8M6@1268|Micrococcaceae	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase	paaI	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HKD2_k127_6484023_1	1150398.JIBJ01000005_gene3132	3.538e-89	312.0	COG2151@1|root,COG2151@2|Bacteria,2II4H@201174|Actinobacteria,1W96G@1268|Micrococcaceae	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase	paaJ	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
HKD2_k127_6484023_2	1150398.JIBJ01000005_gene3133	6.218e-16	78.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,1W7N8@1268|Micrococcaceae	201174|Actinobacteria	C	Phenylacetate-CoA oxygenase reductase, PaaK subunit	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,FA_desaturase,Fer2,NAD_binding_1
HKD2_k127_6490014_0	1158050.KB895462_gene3887	1.057e-203	636.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,1W7FM@1268|Micrococcaceae	201174|Actinobacteria	I	carboxylase	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
HKD2_k127_6490014_1	1150398.JIBJ01000006_gene3505	7.087e-114	369.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,1W917@1268|Micrococcaceae	201174|Actinobacteria	D	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
HKD2_k127_6495385_2	930171.Asphe3_19710	1.988e-36	139.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,1W9PA@1268|Micrococcaceae	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HKD2_k127_6495385_1	1150398.JIBJ01000004_gene2919	3.233e-73	250.0	COG2337@1|root,COG2337@2|Bacteria,2GM10@201174|Actinobacteria,1W9KJ@1268|Micrococcaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
HKD2_k127_6495385_0	1101188.KI912155_gene3293	6.673e-313	966.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,1W80C@1268|Micrococcaceae	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
HKD2_k127_6500223_0	1150398.JIBJ01000006_gene3479	2.319e-246	762.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,1W7IC@1268|Micrococcaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HKD2_k127_6500223_1	290399.Arth_1306	1.559e-55	195.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,1W9RS@1268|Micrococcaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HKD2_k127_6501965_1	1151119.KB895518_gene2619	2.173e-175	580.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,1W84F@1268|Micrococcaceae	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD2_k127_6501965_0	290399.Arth_1530	3.371e-248	774.0	COG1301@1|root,COG1301@2|Bacteria,2GK6U@201174|Actinobacteria,1W7IK@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
HKD2_k127_6501965_2	290399.Arth_1529	2.643e-87	294.0	COG3290@1|root,COG3290@2|Bacteria,2GIRZ@201174|Actinobacteria,1W918@1268|Micrococcaceae	201174|Actinobacteria	T	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8,SPOB_a,sCache_3_2
HKD2_k127_6512915_0	1312959.KI914663_gene3624	1.08e-118	394.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE,EAL,GGDEF
HKD2_k127_6512915_2	1158050.KB895455_gene1813	1.068e-50	182.0	2DS7J@1|root,33EW7@2|Bacteria,2H97C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
HKD2_k127_6512915_1	290399.Arth_1881	3.665e-62	220.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Acetyltransf_3
HKD2_k127_6512915_3	290399.Arth_1882	3.356e-06	51.0	2EI9I@1|root,33C0W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6528028_2	1150398.JIBJ01000005_gene3431	0.0	1006.0	COG0747@1|root,COG0747@2|Bacteria,2GMMG@201174|Actinobacteria,1W8VD@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD2_k127_6528028_4	1150398.JIBJ01000005_gene3432	5.747e-284	879.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,1W7V0@1268|Micrococcaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD2_k127_6528028_5	1150398.JIBJ01000005_gene3433	9.137e-195	612.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,1W7UC@1268|Micrococcaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HKD2_k127_6528028_8	290399.Arth_2824	2.475e-96	318.0	2E7VQ@1|root,332AI@2|Bacteria,2IMG7@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_6
HKD2_k127_6528028_0	1150398.JIBJ01000005_gene3435	0.0	1071.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,1W7RX@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HKD2_k127_6528028_1	290399.Arth_2822	0.0	1058.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,1W7W7@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	dppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
HKD2_k127_6528028_7	1276920.ADIAG_01208	2.693e-137	442.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,1W8S7@1268|Micrococcaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
HKD2_k127_6528028_6	290399.Arth_2820	1.617e-189	595.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,1W8T0@1268|Micrococcaceae	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	dppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
HKD2_k127_6528028_3	290399.Arth_2819	1e-323	997.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,1W7RX@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HKD2_k127_6531487_2	1077972.ARGLB_010_00830	1.238e-46	167.0	COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,1W7Q4@1268|Micrococcaceae	201174|Actinobacteria	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD2_k127_6531487_0	1150398.JIBJ01000006_gene3635	2.294e-197	619.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,1W811@1268|Micrococcaceae	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HKD2_k127_6531487_3	351607.Acel_0391	2.721e-45	174.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria,4ESTP@85013|Frankiales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD2_k127_6531487_1	1150398.JIBJ01000006_gene3633	4.093e-145	468.0	COG1295@1|root,COG1295@2|Bacteria,2GN79@201174|Actinobacteria,1W9I6@1268|Micrococcaceae	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD2_k127_6550360_0	1177594.MIC448_1720003	5.586e-124	404.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4FN03@85023|Microbacteriaceae	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HKD2_k127_6550360_1	1304872.JAGC01000003_gene2526	3.379e-53	195.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2MGE3@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HKD2_k127_6557371_1	1077972.ARGLB_047_00630	1.275e-99	326.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,1W87H@1268|Micrococcaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD2_k127_6557371_3	1151119.KB895503_gene3083	2.585e-98	327.0	COG1124@1|root,COG1124@2|Bacteria,2I5T0@201174|Actinobacteria,1W99V@1268|Micrococcaceae	201174|Actinobacteria	EP	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6557371_0	1150398.JIBJ01000002_gene885	6.695e-321	993.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,1W8KG@1268|Micrococcaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
HKD2_k127_6557371_2	1449044.JMLE01000011_gene3426	1.753e-98	348.0	COG1309@1|root,COG1309@2|Bacteria,2GJBV@201174|Actinobacteria,1W906@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_6566271_2	930171.Asphe3_05010	2.765e-47	169.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,1W9YD@1268|Micrococcaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
HKD2_k127_6566271_0	1150398.JIBJ01000002_gene1148	1.732e-156	507.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,1W8XK@1268|Micrococcaceae	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
HKD2_k127_6566271_1	1150398.JIBJ01000002_gene1149	2.669e-119	387.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,1WB69@1268|Micrococcaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
HKD2_k127_6585402_1	1158050.KB895454_gene1492	2.89e-85	286.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,1W8NQ@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HKD2_k127_6585402_0	930171.Asphe3_20470	0.0	1218.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,1W7U2@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
HKD2_k127_6589480_3	1304876.AZVC01000010_gene2256	3.342e-15	76.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,1W9YJ@1268|Micrococcaceae	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
HKD2_k127_6589480_1	1449044.JMLE01000020_gene1866	9.801e-62	226.0	COG2968@1|root,COG2968@2|Bacteria,2IPEJ@201174|Actinobacteria,1WBC7@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
HKD2_k127_6589480_2	1150398.JIBJ01000009_gene446	9.997e-54	194.0	2CR5C@1|root,32SNF@2|Bacteria,2IT0H@201174|Actinobacteria,1W9Y1@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
HKD2_k127_6589480_0	290399.Arth_1489	3.044e-191	597.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,1W80T@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HKD2_k127_6589681_0	1150398.JIBJ01000005_gene3238	0.0	1013.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,1W8MG@1268|Micrococcaceae	201174|Actinobacteria	G	PFAM alpha amylase, catalytic	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
HKD2_k127_6601956_1	1385935.N836_22145	5.132e-13	73.0	COG2963@1|root,COG2963@2|Bacteria,1GAKB@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
HKD2_k127_6601956_0	1487953.JMKF01000069_gene148	2.146e-94	319.0	COG2801@1|root,COG2801@2|Bacteria,1G5GD@1117|Cyanobacteria,1HGQD@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
HKD2_k127_6612016_1	1449044.JMLE01000031_gene72	1.575e-81	273.0	COG1109@1|root,COG1109@2|Bacteria,2GJ3Q@201174|Actinobacteria,1W7VY@1268|Micrococcaceae	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pmmB	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD2_k127_6612016_2	1150398.JIBJ01000006_gene3521	1.09e-48	179.0	COG2146@1|root,COG2146@2|Bacteria,2IQM4@201174|Actinobacteria,1WA1Z@1268|Micrococcaceae	201174|Actinobacteria	P	Nitrite reductase NAD(P)H , small subunit	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
HKD2_k127_6612016_0	1150398.JIBJ01000006_gene3522	5.593e-235	734.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,1W8TN@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
HKD2_k127_6623670_0	1150398.JIBJ01000014_gene2438	2.183e-110	367.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,1W9HM@1268|Micrococcaceae	201174|Actinobacteria	M	cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
HKD2_k127_6623670_1	1077972.ARGLB_051_01170	3.176e-99	327.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,1W7MP@1268|Micrococcaceae	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD2_k127_6630289_2	1150398.JIBJ01000006_gene3538	1.142e-274	868.0	COG2909@1|root,COG2909@2|Bacteria,2GM03@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,GerE
HKD2_k127_6630289_0	1150398.JIBJ01000006_gene3539	0.0	1043.0	COG1474@1|root,COG2197@1|root,COG1474@2|Bacteria,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria,1WC20@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HKD2_k127_6630289_1	1150398.JIBJ01000006_gene3540	1.921e-301	932.0	COG2197@1|root,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HKD2_k127_6649276_2	1108045.GORHZ_155_00110	7.603e-09	59.0	2DMMA@1|root,32SDH@2|Bacteria,2IM8C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
HKD2_k127_6649276_0	749414.SBI_08641	6.362e-71	256.0	COG3293@1|root,COG3293@2|Bacteria,2GMT0@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
HKD2_k127_6649276_1	2002.JOEQ01000094_gene7915	1.665e-57	204.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4EQG3@85012|Streptosporangiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_6651921_3	1150398.JIBJ01000011_gene2342	7.591e-08	57.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	prtR	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
HKD2_k127_6651921_2	1449044.JMLE01000002_gene4236	7.855e-63	218.0	COG1826@1|root,COG1826@2|Bacteria,2IR0U@201174|Actinobacteria,1W9S3@1268|Micrococcaceae	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0008150,GO:0040007	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HKD2_k127_6651921_0	1150398.JIBJ01000011_gene2340	1.974e-196	623.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,1W86X@1268|Micrococcaceae	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HKD2_k127_6651921_1	1449044.JMLE01000002_gene4234	2.715e-109	357.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria,1W8YU@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
HKD2_k127_667_0	1150398.JIBJ01000020_gene3823	2.722e-149	484.0	COG1157@1|root,COG1157@2|Bacteria,2GKGV@201174|Actinobacteria,1WAT4@1268|Micrococcaceae	201174|Actinobacteria	NU	ATP synthase alpha/beta family, nucleotide-binding domain	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD2_k127_667_1	1150398.JIBJ01000020_gene3824	9.037e-98	327.0	COG1317@1|root,COG1317@2|Bacteria,2ISF1@201174|Actinobacteria	201174|Actinobacteria	NU	Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
HKD2_k127_667_2	1150398.JIBJ01000020_gene3825	8.136e-39	145.0	COG1536@1|root,COG1536@2|Bacteria,2GP1H@201174|Actinobacteria	201174|Actinobacteria	N	flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
HKD2_k127_6672563_1	1150398.JIBJ01000009_gene359	6.023e-53	188.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,1W8B7@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
HKD2_k127_6672563_0	1077972.ARGLB_098_00030	9.356e-135	433.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,1W98E@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
HKD2_k127_6680528_0	1150398.JIBJ01000002_gene1278	2.107e-210	656.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,1W8A6@1268|Micrococcaceae	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD2_k127_6680528_3	1449044.JMLE01000006_gene1062	5.797e-108	364.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,1W813@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HKD2_k127_6680528_2	290399.Arth_0149	3.53e-163	541.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,1W7SE@1268|Micrococcaceae	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
HKD2_k127_6680528_1	1449044.JMLE01000006_gene1060	2.346e-200	639.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,1W89H@1268|Micrococcaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
HKD2_k127_6680528_4	1449044.JMLE01000006_gene1058	3.903e-76	258.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,1W8MK@1268|Micrococcaceae	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD2_k127_6689930_1	1158050.KB895452_gene87	4.061e-139	443.0	COG0579@1|root,COG0579@2|Bacteria,2GJZ8@201174|Actinobacteria,1W8MW@1268|Micrococcaceae	201174|Actinobacteria	C	malate quinone oxidoreductase	mqo	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0044424,GO:0044464,GO:0055114,GO:0071944	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
HKD2_k127_6689930_0	1449044.JMLE01000016_gene864	3.69e-303	936.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,1W8B4@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD2_k127_6689930_2	1150398.JIBJ01000019_gene870	6.471e-105	346.0	COG2335@1|root,COG2335@2|Bacteria,2GJC2@201174|Actinobacteria	201174|Actinobacteria	M	Fasciclin	mpt	GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fasciclin
HKD2_k127_6689930_3	1077972.ARGLB_096_00070	2.542e-81	273.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,1W9A9@1268|Micrococcaceae	201174|Actinobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD2_k127_6689930_4	290399.Arth_2545	1.762e-69	239.0	COG1846@1|root,COG1846@2|Bacteria,2IQXC@201174|Actinobacteria,1W9JU@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HKD2_k127_6689930_6	1463825.JNXC01000005_gene2397	2.068e-05	48.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria,4E2P0@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
HKD2_k127_6689930_5	1151119.KB895488_gene922	2.897e-20	91.0	COG0091@1|root,COG0091@2|Bacteria	2|Bacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6726490_4	290399.Arth_1453	2.192e-163	515.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,1W7VF@1268|Micrococcaceae	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HKD2_k127_6726490_3	1150398.JIBJ01000009_gene406	9.482e-170	542.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,1W7MR@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD2_k127_6726490_2	1449044.JMLE01000020_gene1907	2.731e-178	566.0	COG3503@1|root,COG3503@2|Bacteria,2I2JM@201174|Actinobacteria,1W95A@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
HKD2_k127_6726490_8	1150398.JIBJ01000009_gene402	4.678e-77	273.0	COG5010@1|root,COG5010@2|Bacteria,2IFHE@201174|Actinobacteria,1WCN7@1268|Micrococcaceae	201174|Actinobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6726490_5	1151119.KB895508_gene469	5.221e-135	435.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,1W8N2@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HKD2_k127_6726490_10	1101188.KI912155_gene2678	5.646e-76	258.0	COG0314@1|root,COG0314@2|Bacteria,2IQ9F@201174|Actinobacteria,1W9EC@1268|Micrococcaceae	201174|Actinobacteria	H	MoaE protein	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
HKD2_k127_6726490_6	1150398.JIBJ01000009_gene397	1.043e-87	303.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,1W9TB@1268|Micrococcaceae	201174|Actinobacteria	H	Probable molybdopterin binding domain	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
HKD2_k127_6726490_9	1150398.JIBJ01000009_gene396	5.31e-76	257.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,1W98T@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0008150,GO:0009605,GO:0009607,GO:0031347,GO:0031348,GO:0035821,GO:0040007,GO:0043207,GO:0044003,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0075136,GO:0080134	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
HKD2_k127_6726490_1	1150398.JIBJ01000009_gene395	2.713e-180	573.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,1W92T@1268|Micrococcaceae	201174|Actinobacteria	H	molybdenum cofactor	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HKD2_k127_6726490_0	1151118.KB895792_gene1977	2.392e-196	629.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,1W8AY@1268|Micrococcaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
HKD2_k127_6726490_7	1449044.JMLE01000020_gene1915	1.711e-83	279.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,1W7G0@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HKD2_k127_673166_2	1077972.ARGLB_091_00320	9.409e-34	130.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
HKD2_k127_673166_0	1150398.JIBJ01000003_gene1527	2.448e-53	197.0	COG1183@1|root,COG1183@2|Bacteria,2I5UA@201174|Actinobacteria,1WCEE@1268|Micrococcaceae	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
HKD2_k127_673166_1	1150398.JIBJ01000003_gene1526	2.299e-45	171.0	2E7W4@1|root,332AV@2|Bacteria,2IMEE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_673166_3	1150398.JIBJ01000004_gene2968	6.323e-17	81.0	COG3794@1|root,COG3794@2|Bacteria,2GS7W@201174|Actinobacteria	201174|Actinobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
HKD2_k127_6733365_4	1150398.JIBJ01000006_gene3537	1.16e-09	61.0	COG1474@1|root,COG2197@1|root,COG1474@2|Bacteria,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria,1WAFR@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HKD2_k127_6733365_0	1150398.JIBJ01000006_gene3536	7.785e-241	749.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,1W7H4@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
HKD2_k127_6733365_1	1150398.JIBJ01000006_gene3535	2.519e-73	249.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,1W9Q2@1268|Micrococcaceae	201174|Actinobacteria	C	SUF system FeS assembly protein	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HKD2_k127_6733365_2	1150398.JIBJ01000006_gene3532	5.055e-31	122.0	2ERSU@1|root,33JC1@2|Bacteria,2GX4U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6733365_3	1349820.M707_05575	1.197e-22	97.0	COG3832@1|root,COG3832@2|Bacteria,2IS30@201174|Actinobacteria,1W9PU@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
HKD2_k127_6734164_1	1166018.FAES_2561	7.888e-32	128.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
HKD2_k127_6734164_3	1123393.KB891328_gene684	2.64e-05	51.0	COG4736@1|root,COG4736@2|Bacteria,1PWVN@1224|Proteobacteria,2WCEC@28216|Betaproteobacteria,1KTI8@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Cbb3-type cytochrome oxidase component FixQ	-	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
HKD2_k127_6734164_0	278957.ABEA03000019_gene1944	1.176e-36	149.0	COG2010@1|root,COG2010@2|Bacteria,46SVP@74201|Verrucomicrobia,3K83H@414999|Opitutae	414999|Opitutae	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
HKD2_k127_6734164_2	1123253.AUBD01000016_gene1974	1.231e-29	122.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1X4FV@135614|Xanthomonadales	135614|Xanthomonadales	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
HKD2_k127_6734417_1	1150398.JIBJ01000009_gene418	4.239e-165	520.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,1W7KM@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD2_k127_6734417_2	1132441.KI519454_gene508	1.09e-90	306.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,1W8XQ@1268|Micrococcaceae	201174|Actinobacteria	J	Methyltransferase	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
HKD2_k127_6734417_0	1150398.JIBJ01000009_gene420	2.119e-297	920.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,1W7ZF@1268|Micrococcaceae	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD2_k127_6734417_3	930171.Asphe3_14500	3.556e-82	278.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,1W7Y0@1268|Micrococcaceae	201174|Actinobacteria	L	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
HKD2_k127_6766023_1	930171.Asphe3_12430	1.575e-95	317.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,1W9EG@1268|Micrococcaceae	201174|Actinobacteria	K	tetR family	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_6766023_0	1077972.ARGLB_043_00120	3.222e-143	460.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,1W8CB@1268|Micrococcaceae	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
HKD2_k127_6796244_0	446471.Xcel_2469	1.448e-18	99.0	COG4118@1|root,COG4118@2|Bacteria,2HCMM@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
HKD2_k127_6796244_1	106370.Francci3_2058	5.682e-06	48.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4EWGM@85013|Frankiales	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_6796356_0	1150398.JIBJ01000003_gene1905	2.842e-300	926.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,1W87A@1268|Micrococcaceae	201174|Actinobacteria	CJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
HKD2_k127_6796356_1	1150398.JIBJ01000003_gene1904	6.665e-134	429.0	29850@1|root,2ZVAX@2|Bacteria,2GKR1@201174|Actinobacteria,1W99A@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6796524_2	1077972.ARGLB_074_00640	7.447e-45	162.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,1W7P8@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
HKD2_k127_6796524_3	1150398.JIBJ01000004_gene2710	8.269e-31	122.0	2BAQ6@1|root,32453@2|Bacteria,2H8YV@201174|Actinobacteria,1WBZQ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6796524_0	1449044.JMLE01000001_gene3776	1.635e-113	371.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,1W82V@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD2_k127_6796524_1	1150398.JIBJ01000004_gene2712	1.494e-89	305.0	2B7HY@1|root,320NA@2|Bacteria,2H4EF@201174|Actinobacteria,1WB89@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6796978_1	1449044.JMLE01000001_gene3897	1.84e-63	226.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,1W905@1268|Micrococcaceae	201174|Actinobacteria	E	shikimate dehydrogenase	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
HKD2_k127_6796978_0	1150398.JIBJ01000004_gene2876	5.721e-198	626.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,1W86T@1268|Micrococcaceae	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD2_k127_680377_3	452863.Achl_2544	1.076e-85	287.0	COG0300@1|root,COG0300@2|Bacteria,2HJGE@201174|Actinobacteria,1WBSE@1268|Micrococcaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_680377_1	1449044.JMLE01000009_gene3156	7.107e-97	318.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,1WB49@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
HKD2_k127_680377_0	1122997.AUDD01000009_gene230	1.506e-125	412.0	COG0329@1|root,COG0329@2|Bacteria,2HM5H@201174|Actinobacteria	201174|Actinobacteria	EM	Belongs to the DapA family	dapA4	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD2_k127_680377_2	1312954.KI914885_gene2527	1.575e-95	317.0	COG3046@1|root,COG3046@2|Bacteria,2GMF6@201174|Actinobacteria	201174|Actinobacteria	S	deoxyribodipyrimidine	cry1	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
HKD2_k127_6806193_2	1150398.JIBJ01000009_gene329	3.079e-49	175.0	COG3275@1|root,COG3275@2|Bacteria,2GJD4@201174|Actinobacteria,1W8CN@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,His_kinase
HKD2_k127_6806193_1	1150398.JIBJ01000009_gene328	3.619e-134	435.0	COG3279@1|root,COG3279@2|Bacteria,2GKK5@201174|Actinobacteria,1W932@1268|Micrococcaceae	201174|Actinobacteria	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD2_k127_6806193_3	1150398.JIBJ01000009_gene327	7.072e-46	174.0	2E3NY@1|root,32YM2@2|Bacteria,2II83@201174|Actinobacteria,1W9VQ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6806193_0	290399.Arth_1373	6.705e-145	462.0	COG4147@1|root,COG4147@2|Bacteria,2GM3H@201174|Actinobacteria,1W8K6@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
HKD2_k127_6820097_1	1101188.KI912155_gene1778	2.929e-130	426.0	COG0697@1|root,COG0697@2|Bacteria,2H1HG@201174|Actinobacteria,1W96Q@1268|Micrococcaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
HKD2_k127_6820097_4	1150398.JIBJ01000002_gene888	2.944e-39	154.0	2DRPJ@1|root,33CGW@2|Bacteria,2HYWU@201174|Actinobacteria,1WC6P@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6820097_2	290399.Arth_0659	2.348e-106	345.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,1W9MK@1268|Micrococcaceae	201174|Actinobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
HKD2_k127_6820097_0	1150398.JIBJ01000002_gene891	6.063e-155	492.0	COG0745@1|root,COG0745@2|Bacteria,2IAQJ@201174|Actinobacteria,1W83X@1268|Micrococcaceae	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HKD2_k127_6838756_2	345341.KUTG_04140	6.386e-31	126.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6838756_1	1449044.JMLE01000001_gene3718	1.479e-130	422.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD2_k127_6838756_0	1150398.JIBJ01000004_gene2645	1.282e-137	440.0	COG3022@1|root,COG3022@2|Bacteria,2GJPM@201174|Actinobacteria,1W8F9@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0246 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
HKD2_k127_6864383_0	290399.Arth_3885	2.383e-244	756.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,1W7V4@1268|Micrococcaceae	201174|Actinobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD2_k127_6864811_0	290399.Arth_1385	1.353e-195	618.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,1W82J@1268|Micrococcaceae	201174|Actinobacteria	I	carboxylase	accD1	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD2_k127_6864811_1	1449044.JMLE01000023_gene175	6.45e-68	234.0	COG1309@1|root,COG1309@2|Bacteria,2GIUW@201174|Actinobacteria,1W98S@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_6865012_1	290399.Arth_0195	2.074e-223	693.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,1W8CV@1268|Micrococcaceae	201174|Actinobacteria	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD2_k127_6865012_0	290399.Arth_0197	3.92e-249	775.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,1W8GQ@1268|Micrococcaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copB	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
HKD2_k127_6870335_0	768710.DesyoDRAFT_3154	9.478e-43	167.0	COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,24AQA@186801|Clostridia,261N3@186807|Peptococcaceae	186801|Clostridia	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
HKD2_k127_6870335_1	1569209.BBPH01000095_gene1458	1.749e-11	73.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2PW8K@265|Paracoccus	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
HKD2_k127_6877883_3	1150398.JIBJ01000002_gene1012	6.381e-13	68.0	COG5450@1|root,32SQA@2|Bacteria,2IKJX@201174|Actinobacteria,1W9FF@1268|Micrococcaceae	201174|Actinobacteria	K	Transcription regulator of the Arc MetJ class	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6877883_1	1150398.JIBJ01000002_gene1013	5.397e-163	516.0	COG0561@1|root,COG0561@2|Bacteria,2IAAY@201174|Actinobacteria,1W99R@1268|Micrococcaceae	201174|Actinobacteria	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6877883_0	1150398.JIBJ01000002_gene1014	4.533e-317	974.0	COG0438@1|root,COG0438@2|Bacteria,2GJBP@201174|Actinobacteria,1WAZM@1268|Micrococcaceae	201174|Actinobacteria	M	Stealth protein CR3, conserved region 3	cpsY	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
HKD2_k127_6877883_2	1150398.JIBJ01000002_gene1015	1.653e-33	130.0	COG1409@1|root,COG1409@2|Bacteria,2HKQQ@201174|Actinobacteria,1WB44@1268|Micrococcaceae	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD2_k127_6905740_3	1150398.JIBJ01000005_gene3367	2.194e-76	260.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,1W9H6@1268|Micrococcaceae	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD2_k127_6905740_0	1150398.JIBJ01000005_gene3366	9.015e-219	683.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,1W7P9@1268|Micrococcaceae	201174|Actinobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,TsaE
HKD2_k127_6905740_1	1150398.JIBJ01000005_gene3365	3.846e-209	660.0	COG0524@1|root,COG0524@2|Bacteria,2GKQP@201174|Actinobacteria	201174|Actinobacteria	G	Carbohydrate kinase	scrK	-	-	-	-	-	-	-	-	-	-	-	PfkB
HKD2_k127_6905740_2	1150398.JIBJ01000005_gene3364	2.035e-97	331.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria	201174|Actinobacteria	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
HKD2_k127_6913370_2	1150398.JIBJ01000008_gene660	2.437e-32	135.0	2DQKZ@1|root,337IN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
HKD2_k127_6913370_1	1077972.ARGLB_073_00220	9.389e-38	143.0	2EGRW@1|root,33AI2@2|Bacteria,2HT9I@201174|Actinobacteria,1W9ZS@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
HKD2_k127_6913370_0	1150398.JIBJ01000008_gene659	5.648e-118	385.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD2_k127_6913370_3	1349820.M707_12495	1.647e-20	91.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,1W7UB@1268|Micrococcaceae	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD2_k127_6926370_6	290399.Arth_1633	5.283e-53	190.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,1W93E@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
HKD2_k127_6926370_5	1077972.ARGLB_051_00550	9.984e-54	192.0	2ATJW@1|root,32RNQ@2|Bacteria,2I810@201174|Actinobacteria,1W9IK@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
HKD2_k127_6926370_4	290399.Arth_1635	4.978e-69	243.0	2E4C2@1|root,32Z7M@2|Bacteria,2IFS5@201174|Actinobacteria,1W97E@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3093)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3093
HKD2_k127_6926370_3	1077972.ARGLB_051_00530	2.283e-77	272.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,1W91W@1268|Micrococcaceae	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HKD2_k127_6926370_1	1150398.JIBJ01000003_gene1898	2.995e-110	364.0	28J4D@1|root,30NZ9@2|Bacteria,2I2E9@201174|Actinobacteria,1W9GR@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
HKD2_k127_6926370_7	1077972.ARGLB_051_00510	1.337e-37	152.0	COG1200@1|root,COG1200@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
HKD2_k127_6926370_0	1150398.JIBJ01000003_gene1896	5.043e-113	376.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,1W90J@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
HKD2_k127_6926370_2	1449044.JMLE01000009_gene3273	3.77e-78	264.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,1W7MF@1268|Micrococcaceae	201174|Actinobacteria	P	Putative NAD(P)-binding	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD2_k127_694681_1	1150398.JIBJ01000002_gene946	4.961e-92	306.0	COG1309@1|root,COG1309@2|Bacteria,2IJIU@201174|Actinobacteria	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_694681_0	1150398.JIBJ01000002_gene943	2.768e-105	346.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
HKD2_k127_6988603_0	290340.AAur_3971	1.459e-151	486.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,1W8T8@1268|Micrococcaceae	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
HKD2_k127_6988603_1	1077972.ARGLB_080_00520	6.059e-96	325.0	COG4291@1|root,COG4291@2|Bacteria,2IIVD@201174|Actinobacteria,1W9T4@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
HKD2_k127_6988603_2	1158050.KB895456_gene2104	3.141e-59	205.0	COG3511@1|root,COG3511@2|Bacteria,2IC2P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
HKD2_k127_7001610_2	290399.Arth_3407	1.046e-204	643.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,1W8AY@1268|Micrococcaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
HKD2_k127_7001610_0	1150398.JIBJ01000012_gene2047	9.769e-248	768.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,1W832@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD2_k127_7001610_3	1150398.JIBJ01000012_gene2046	1.642e-176	561.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,1W7X6@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HKD2_k127_7001610_1	1150398.JIBJ01000012_gene2045	8.961e-232	722.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2IS61@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,TPR_6
HKD2_k127_7001610_6	1123024.AUII01000023_gene262	1.065e-05	52.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
HKD2_k127_7001610_4	290399.Arth_3403	1.84e-28	116.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,1W7RR@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_7001800_7	288705.RSal33209_2242	1.501e-30	124.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,1W7NC@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_7001800_4	1150398.JIBJ01000004_gene3044	2.891e-122	402.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,1W8GF@1268|Micrococcaceae	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD2_k127_7001800_3	290399.Arth_2099	1.822e-160	511.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,1W7TW@1268|Micrococcaceae	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
HKD2_k127_7001800_5	452863.Achl_1764	2.238e-87	293.0	COG0586@1|root,COG0586@2|Bacteria,2IA3P@201174|Actinobacteria	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD2_k127_7001800_2	1449044.JMLE01000001_gene4084	2.082e-190	596.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,1W7N9@1268|Micrococcaceae	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
HKD2_k127_7001800_0	290399.Arth_2097	0.0	1289.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,1W7N4@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
HKD2_k127_7001800_1	1449044.JMLE01000001_gene4086	4.728e-209	653.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,1W8SQ@1268|Micrococcaceae	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HKD2_k127_7001800_6	1150398.JIBJ01000004_gene3036	3.186e-61	214.0	COG0166@1|root,COG0166@2|Bacteria,2HT2Q@201174|Actinobacteria,1W8PK@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD2_k127_7006026_0	1279017.AQYJ01000023_gene3265	4.094e-49	194.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	2.4.1.10	ko:K00692	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R05140	RC00077	ko00000,ko00001,ko01000,ko01003	-	GH68	-	Alpha-L-AF_C,Alpha-amylase,Big_2,CBM_4_9,Glyco_hydro_32N,Glyco_hydro_43,Glyco_hydro_66,Glyco_hydro_68,Laminin_G_3,PUD,SLH,VCBS
HKD2_k127_700906_1	1150398.JIBJ01000004_gene2841	1.156e-96	321.0	COG2267@1|root,COG2267@2|Bacteria,2I2Q9@201174|Actinobacteria,1WBC5@1268|Micrococcaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD2_k127_700906_2	1304876.AZVC01000013_gene2653	1.008e-57	205.0	COG1246@1|root,COG1246@2|Bacteria,2I5U0@201174|Actinobacteria,1WBRZ@1268|Micrococcaceae	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD2_k127_700906_0	1449044.JMLE01000001_gene3860	4.457e-111	368.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,1W7IS@1268|Micrococcaceae	201174|Actinobacteria	S	glutamine amidotransferase	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
HKD2_k127_7023863_1	1158050.KB895454_gene1233	3.508e-128	417.0	2DBB1@1|root,2Z854@2|Bacteria,2GNBN@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
HKD2_k127_7023863_2	1151119.KB895491_gene1885	5.291e-21	94.0	COG3237@1|root,COG3237@2|Bacteria,2GQQ4@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
HKD2_k127_7023863_0	1150398.JIBJ01000001_gene1382	1.162e-249	788.0	COG2730@1|root,COG2730@2|Bacteria,2I2VY@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase family 5	celA	-	3.2.1.4	ko:K01179,ko:K20628	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase,fn3
HKD2_k127_7023863_3	1035308.AQYY01000002_gene301	9.888e-10	59.0	COG1028@1|root,COG1028@2|Bacteria	1035308.AQYY01000002_gene301|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7049282_1	1121937.AUHJ01000010_gene1750	2.692e-26	111.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,466RA@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0656 Aldo keto reductases, related to diketogulonate reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_7049282_0	1232410.KI421421_gene3631	7.063e-170	542.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
HKD2_k127_7071905_0	1150398.JIBJ01000005_gene3150	6.931e-238	741.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,1W7T6@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
HKD2_k127_7091207_4	1449044.JMLE01000014_gene2316	3.936e-31	122.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,1W8HQ@1268|Micrococcaceae	201174|Actinobacteria	I	CoA-transferase	pcaI	-	2.8.3.6	ko:K01031	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_7091207_0	1151119.KB895493_gene1425	1.121e-226	708.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,1W8Q0@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_7091207_3	1151119.KB895493_gene1426	2.491e-76	262.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,1W9KC@1268|Micrococcaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
HKD2_k127_7091207_2	290399.Arth_4075	2.868e-141	455.0	COG2267@1|root,COG2267@2|Bacteria,2I3KS@201174|Actinobacteria,1W95S@1268|Micrococcaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	pcaD	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
HKD2_k127_7091207_1	290399.Arth_4076	1.131e-197	625.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,1W8EA@1268|Micrococcaceae	201174|Actinobacteria	F	Adenylosuccinate lyase C-terminus	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
HKD2_k127_7098791_4	1150398.JIBJ01000020_gene3820	3.141e-54	203.0	COG3144@1|root,COG3144@2|Bacteria,2GQY6@201174|Actinobacteria	201174|Actinobacteria	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
HKD2_k127_7098791_3	1150398.JIBJ01000020_gene3819	5.139e-57	202.0	COG1843@1|root,COG1843@2|Bacteria,2IQIQ@201174|Actinobacteria	201174|Actinobacteria	N	Flagellar hook capping protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD
HKD2_k127_7098791_0	1150398.JIBJ01000020_gene3818	9.685e-182	575.0	COG1749@1|root,COG1749@2|Bacteria,2I62V@201174|Actinobacteria	201174|Actinobacteria	N	Flagellar basal body rod protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
HKD2_k127_7098791_5	1150398.JIBJ01000020_gene3814	1.184e-41	158.0	COG1582@1|root,COG1582@2|Bacteria,2GRTC@201174|Actinobacteria	201174|Actinobacteria	N	PFAM flagellar FlbD family protein	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
HKD2_k127_7098791_1	1150398.JIBJ01000020_gene3813	1.684e-135	435.0	COG1291@1|root,COG1291@2|Bacteria,2I92C@201174|Actinobacteria	201174|Actinobacteria	N	MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
HKD2_k127_7098791_2	1150398.JIBJ01000020_gene3812	1.769e-125	424.0	COG1360@1|root,COG1360@2|Bacteria,2IG81@201174|Actinobacteria	201174|Actinobacteria	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
HKD2_k127_7098791_6	1150398.JIBJ01000020_gene3811	1.377e-17	83.0	COG1868@1|root,COG1868@2|Bacteria,2ICP2@201174|Actinobacteria	201174|Actinobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
HKD2_k127_7108133_1	290399.Arth_0193	6.792e-75	252.0	COG2508@1|root,COG2508@2|Bacteria,2GR38@201174|Actinobacteria,1W87S@1268|Micrococcaceae	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
HKD2_k127_7108133_0	1150398.JIBJ01000002_gene1252	1.343e-210	663.0	COG0515@1|root,COG2203@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,2IAZC@201174|Actinobacteria,1W9CQ@1268|Micrococcaceae	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Pkinase
HKD2_k127_7108133_2	452863.Achl_0346	3.897e-41	151.0	COG4108@1|root,COG4108@2|Bacteria,2GKQA@201174|Actinobacteria,1WB6R@1268|Micrococcaceae	201174|Actinobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
HKD2_k127_7120995_0	290399.Arth_3922	5.562e-190	599.0	COG4097@1|root,COG4097@2|Bacteria,2GKWX@201174|Actinobacteria	201174|Actinobacteria	P	ferric reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
HKD2_k127_7120995_1	595593.JREV01000039_gene3773	4.855e-19	87.0	COG0227@1|root,COG0227@2|Bacteria,2IQAT@201174|Actinobacteria,1W9UQ@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD2_k127_7145796_2	525368.HMPREF0591_0172	9.044e-27	126.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,23CCY@1762|Mycobacteriaceae	201174|Actinobacteria	L	N-terminal domain of reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
HKD2_k127_7145796_0	105422.BBPM01000098_gene5214	1.253e-247	785.0	COG1961@1|root,COG1961@2|Bacteria,2INJA@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD2_k127_7145796_1	525368.HMPREF0591_0172	2.373e-27	114.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,23CCY@1762|Mycobacteriaceae	201174|Actinobacteria	L	N-terminal domain of reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
HKD2_k127_7148168_0	290399.Arth_0145	1.549e-164	520.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,1W8S6@1268|Micrococcaceae	201174|Actinobacteria	I	PFAM Carboxylesterase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
HKD2_k127_7148168_1	1115632.JAFW01000001_gene2429	2.466e-102	334.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,1W7DP@1268|Micrococcaceae	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
HKD2_k127_7265084_0	1150398.JIBJ01000004_gene2838	8.622e-312	957.0	COG0339@1|root,COG0339@2|Bacteria,2GM2Z@201174|Actinobacteria,1W7UD@1268|Micrococcaceae	201174|Actinobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
HKD2_k127_7265084_1	1151119.KB895491_gene1817	1.79e-23	99.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,1W7GP@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
HKD2_k127_7277685_0	331869.BAL199_05104	1.256e-100	344.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4BPBH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
HKD2_k127_7277685_1	1007105.PT7_2947	2.173e-29	126.0	COG4665@1|root,COG4665@2|Bacteria,1RK2F@1224|Proteobacteria	1224|Proteobacteria	Q	COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
HKD2_k127_7280283_0	1150398.JIBJ01000020_gene3821	6.368e-92	312.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	3.4.14.13	ko:K20742,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SLT
HKD2_k127_7280283_1	1150398.JIBJ01000020_gene3822	1.751e-52	190.0	2EEBK@1|root,3385W@2|Bacteria,2GU93@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
HKD2_k127_7280283_2	1150398.JIBJ01000020_gene3823	2.032e-11	64.0	COG1157@1|root,COG1157@2|Bacteria,2GKGV@201174|Actinobacteria,1WAT4@1268|Micrococcaceae	201174|Actinobacteria	NU	ATP synthase alpha/beta family, nucleotide-binding domain	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD2_k127_7289732_1	1150398.JIBJ01000003_gene1871	6.294e-78	270.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,1W9EP@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HKD2_k127_7289732_2	1077972.ARGLB_051_00220	6.132e-70	239.0	COG2166@1|root,COG2166@2|Bacteria,2IMBF@201174|Actinobacteria,1W9G9@1268|Micrococcaceae	201174|Actinobacteria	S	Fe-S metabolism associated domain	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
HKD2_k127_7289732_0	290399.Arth_1666	1.913e-188	589.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,1W8G7@1268|Micrococcaceae	201174|Actinobacteria	P	Sulfurtransferase	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD2_k127_7289732_3	1150398.JIBJ01000003_gene1868	2.178e-57	203.0	COG1485@1|root,COG1485@2|Bacteria,2GNQA@201174|Actinobacteria,1W80D@1268|Micrococcaceae	201174|Actinobacteria	S	AFG1-like ATPase	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
HKD2_k127_7307842_1	1150398.JIBJ01000020_gene3811	4.352e-78	262.0	COG1868@1|root,COG1868@2|Bacteria,2ICP2@201174|Actinobacteria	201174|Actinobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
HKD2_k127_7307842_0	1150398.JIBJ01000020_gene3810	4.12e-128	413.0	COG1886@1|root,COG1886@2|Bacteria,2IGHQ@201174|Actinobacteria	201174|Actinobacteria	N	Flagellar motor switch protein FliN	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
HKD2_k127_7307842_3	1150398.JIBJ01000020_gene3809	4.475e-55	198.0	COG3190@1|root,COG3190@2|Bacteria,2GVZZ@201174|Actinobacteria	201174|Actinobacteria	N	Flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
HKD2_k127_7307842_2	1150398.JIBJ01000020_gene3808	4.593e-78	273.0	COG1338@1|root,COG1338@2|Bacteria,2GP63@201174|Actinobacteria	201174|Actinobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
HKD2_k127_7348815_2	1150398.JIBJ01000002_gene1206	3.159e-43	164.0	2DNW5@1|root,32ZGI@2|Bacteria,2IQ5T@201174|Actinobacteria	201174|Actinobacteria	S	Rho termination factor	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
HKD2_k127_7348815_1	1150398.JIBJ01000002_gene1207	2.747e-149	480.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,1W8QJ@1268|Micrococcaceae	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
HKD2_k127_7348815_0	1150398.JIBJ01000002_gene1208	0.0	1069.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,1W81P@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
HKD2_k127_7353212_1	886293.Sinac_5991	5.874e-29	117.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_7353212_0	886293.Sinac_4374	5.43e-215	676.0	COG3464@1|root,COG3464@2|Bacteria,2IZV3@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Uncharacterised protein family (UPF0236)	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_73716_6	1150398.JIBJ01000004_gene2944	1.498e-23	100.0	COG2267@1|root,COG2267@2|Bacteria,2GIVB@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HKD2_k127_73716_4	1449044.JMLE01000001_gene3950	9.043e-159	504.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,1W8EW@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD2_k127_73716_5	1150398.JIBJ01000004_gene2942	3.03e-143	465.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,1W8B1@1268|Micrococcaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HKD2_k127_73716_1	1150398.JIBJ01000004_gene2941	0.0	1108.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,1W8F0@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
HKD2_k127_73716_0	1150398.JIBJ01000004_gene2940	0.0	1120.0	COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,1W7VT@1268|Micrococcaceae	201174|Actinobacteria	O	peptidase M13	pepO	-	3.4.24.11,3.4.24.71	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
HKD2_k127_73716_2	1150398.JIBJ01000004_gene2938	4.372e-247	773.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,1W7KT@1268|Micrococcaceae	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
HKD2_k127_73716_3	930171.Asphe3_19580	2.332e-160	506.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,1W85Z@1268|Micrococcaceae	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD2_k127_7372733_1	219305.MCAG_02126	1.051e-75	266.0	COG0582@1|root,COG0582@2|Bacteria,2GJ2M@201174|Actinobacteria,4D9U1@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD2_k127_7372733_3	928724.SacglDRAFT_02911	3.918e-18	88.0	COG3311@1|root,COG3311@2|Bacteria,2GR55@201174|Actinobacteria,4ED20@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HKD2_k127_7372733_2	543632.JOJL01000043_gene3771	4.234e-34	136.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4DC2W@85008|Micromonosporales	201174|Actinobacteria	L	FOG Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_7372733_0	66874.JOFS01000005_gene3925	5.586e-237	736.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
HKD2_k127_7390684_0	290399.Arth_2503	7.773e-104	339.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,1W94D@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HKD2_k127_7390684_2	1077972.ARGLB_111_00170	1.539e-86	287.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,1W999@1268|Micrococcaceae	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD2_k127_7390684_1	1150398.JIBJ01000017_gene1430	3.517e-101	333.0	COG0300@1|root,COG0300@2|Bacteria,2IAR1@201174|Actinobacteria,1W951@1268|Micrococcaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.105	ko:K07124,ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
HKD2_k127_743408_2	1150398.JIBJ01000003_gene1931	6.111e-38	145.0	COG2047@1|root,COG2047@2|Bacteria,2GK8I@201174|Actinobacteria,1W7IR@1268|Micrococcaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
HKD2_k127_743408_0	1132441.KI519454_gene701	2.177e-220	695.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,1W7GU@1268|Micrococcaceae	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HKD2_k127_743408_1	290340.AAur_1756	6.498e-118	382.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,1W7HP@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoyl dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD2_k127_7499648_2	177437.HRM2_12740	4.936e-16	87.0	COG1589@1|root,COG1589@2|Bacteria,1N3SG@1224|Proteobacteria,42U3W@68525|delta/epsilon subdivisions,2WQPU@28221|Deltaproteobacteria,2MPUX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
HKD2_k127_7499648_0	1121405.dsmv_3405	5.472e-208	659.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD2_k127_7499648_1	933262.AXAM01000013_gene1288	1.164e-93	318.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MHZT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD2_k127_7544466_3	1077972.ARGLB_058_00450	6.668e-09	57.0	COG1994@1|root,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,1W93K@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
HKD2_k127_7544466_1	290340.AAur_2173	1.075e-207	651.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,1W80E@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
HKD2_k127_7544466_0	1132441.KI519454_gene1306	4.616e-312	963.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,1W7N1@1268|Micrococcaceae	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
HKD2_k127_7544466_2	1150398.JIBJ01000013_gene2521	4.835e-88	294.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,1W8F7@1268|Micrococcaceae	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
HKD2_k127_7566827_0	994479.GL877882_gene7062	7.627e-132	436.0	COG4467@1|root,COG4467@2|Bacteria,2INTI@201174|Actinobacteria,4ECV4@85010|Pseudonocardiales	201174|Actinobacteria	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
HKD2_k127_7580194_2	290399.Arth_1570	5.435e-34	137.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,1W7R5@1268|Micrococcaceae	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD2_k127_7580194_0	1150398.JIBJ01000014_gene2435	4.31e-235	737.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,1W7HZ@1268|Micrococcaceae	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
HKD2_k127_7580194_1	1150398.JIBJ01000014_gene2434	1.826e-146	467.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,1W88G@1268|Micrococcaceae	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
HKD2_k127_7597_1	1151119.KB895489_gene547	5.274e-120	389.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,1W7R8@1268|Micrococcaceae	201174|Actinobacteria	M	penicillin-binding protein	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
HKD2_k127_7597_0	930171.Asphe3_05650	0.0	1234.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,1W7MA@1268|Micrococcaceae	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD2_k127_7604706_0	290399.Arth_3442	3.662e-149	488.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,1W81Y@1268|Micrococcaceae	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
HKD2_k127_7604706_1	1150398.JIBJ01000012_gene2055	1.007e-133	429.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,1WBIC@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
HKD2_k127_7604706_2	1150398.JIBJ01000012_gene2056	6.053e-45	168.0	COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,1W8E5@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
HKD2_k127_7641746_0	981369.JQMJ01000001_gene6656	1.243e-127	422.0	COG1609@1|root,COG1609@2|Bacteria,2GK7G@201174|Actinobacteria,2NKXB@228398|Streptacidiphilus	201174|Actinobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
HKD2_k127_7641746_1	66874.JOFS01000044_gene63	3.424e-99	331.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
HKD2_k127_7666680_2	1151119.KB895492_gene1590	5.067e-81	271.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,1W84Y@1268|Micrococcaceae	201174|Actinobacteria	L	ATP-dependent DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD2_k127_7666680_0	290399.Arth_0815	1.794e-233	724.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,1W847@1268|Micrococcaceae	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HKD2_k127_7666680_3	1349820.M707_16780	2.009e-78	267.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,1W8NT@1268|Micrococcaceae	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
HKD2_k127_7666686_0	1150398.JIBJ01000004_gene2679	0.0	1293.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,1W7Z2@1268|Micrococcaceae	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
HKD2_k127_7672453_1	1089553.Tph_c19880	1.62e-140	457.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,42ERZ@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HKD2_k127_7672453_0	1121405.dsmv_0324	6.34e-190	600.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2MIK2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA-2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD2_k127_767991_1	1449044.JMLE01000013_gene2752	4.14e-69	235.0	COG2182@1|root,COG2182@2|Bacteria,2HST8@201174|Actinobacteria,1W7NN@1268|Micrococcaceae	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
HKD2_k127_767991_0	1150398.JIBJ01000027_gene14	1.058e-295	913.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,1W7MN@1268|Micrococcaceae	201174|Actinobacteria	G	N-terminal of TM subunit in PBP-dependent ABC transporters	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,TM_PBP2_N
HKD2_k127_767991_2	290399.Arth_0746	6.195e-11	74.0	COG3833@1|root,COG3833@2|Bacteria,2I2EZ@201174|Actinobacteria,1W8CM@1268|Micrococcaceae	201174|Actinobacteria	G	ABC transporter	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
HKD2_k127_7681128_3	1150398.JIBJ01000010_gene582	7.414e-66	226.0	COG1321@1|root,COG1321@2|Bacteria,2GK7P@201174|Actinobacteria,1W8ST@1268|Micrococcaceae	201174|Actinobacteria	K	iron dependent repressor	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD2_k127_7681128_1	1150398.JIBJ01000010_gene583	1.543e-204	644.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,1W7E2@1268|Micrococcaceae	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	mntH	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
HKD2_k127_7681128_2	1197706.AKKK01000013_gene1945	3.911e-128	415.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,1W8MM@1268|Micrococcaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD2_k127_7681128_0	290399.Arth_2656	1.277e-254	791.0	COG0520@1|root,COG0520@2|Bacteria,2GMIC@201174|Actinobacteria,1W7SQ@1268|Micrococcaceae	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD2_k127_7682298_10	1150398.JIBJ01000010_gene517	9.902e-18	96.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,1W9H8@1268|Micrococcaceae	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
HKD2_k127_7682298_1	1150398.JIBJ01000010_gene516	1.483e-163	525.0	COG0484@1|root,COG0484@2|Bacteria,2IDAA@201174|Actinobacteria,1W86U@1268|Micrococcaceae	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
HKD2_k127_7682298_8	1449044.JMLE01000005_gene743	2.629e-87	289.0	COG0219@1|root,COG0219@2|Bacteria,2IHN9@201174|Actinobacteria,1W93Z@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	spoU	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HKD2_k127_7682298_6	1077972.ARGLB_085_01560	2.076e-104	345.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,1W9WP@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD2_k127_7682298_5	1150398.JIBJ01000010_gene513	1.488e-112	370.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,1WA4R@1268|Micrococcaceae	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	GO:0000988,GO:0000989,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010608,GO:0016020,GO:0016989,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RskA
HKD2_k127_7682298_0	1449044.JMLE01000005_gene746	3.695e-263	814.0	COG2610@1|root,COG2610@2|Bacteria,2GITQ@201174|Actinobacteria,1W7VJ@1268|Micrococcaceae	201174|Actinobacteria	EG	GntP family permease	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
HKD2_k127_7682298_7	1449044.JMLE01000005_gene747	4.635e-91	302.0	COG3265@1|root,COG3265@2|Bacteria,2GMW2@201174|Actinobacteria,1W96P@1268|Micrococcaceae	201174|Actinobacteria	G	TIGRFAM carbohydrate kinase, thermoresistant glucokinase family	gntK	-	2.7.1.12,2.7.1.71	ko:K00851,ko:K00891	ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230	M00022	R01737,R02412	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HKD2_k127_7682298_2	1150398.JIBJ01000010_gene510	1.918e-145	465.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,1W8ZV@1268|Micrococcaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD2_k127_7682298_4	1150398.JIBJ01000010_gene509	1.978e-139	464.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,1W93M@1268|Micrococcaceae	201174|Actinobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HKD2_k127_7682298_3	1150398.JIBJ01000010_gene508	1.86e-141	453.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,1W90M@1268|Micrococcaceae	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD2_k127_7682298_9	1150398.JIBJ01000010_gene507	3.416e-72	245.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,1W7SI@1268|Micrococcaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	degP	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
HKD2_k127_7691178_0	290399.Arth_0145	6.625e-120	389.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,1W8S6@1268|Micrococcaceae	201174|Actinobacteria	I	PFAM Carboxylesterase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
HKD2_k127_7691178_1	930171.Asphe3_02810	9.53e-114	371.0	COG2410@1|root,COG2410@2|Bacteria,2IJME@201174|Actinobacteria,1W99C@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
HKD2_k127_7694140_4	1158050.KB895452_gene165	3.327e-11	75.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
HKD2_k127_7694140_0	1449044.JMLE01000005_gene625	5.69e-178	567.0	COG3227@1|root,COG3227@2|Bacteria,2GJEW@201174|Actinobacteria,1WACU@1268|Micrococcaceae	201174|Actinobacteria	E	Thermolysin metallopeptidase, catalytic domain	prt1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M4,Peptidase_M4_C
HKD2_k127_7694140_2	1150398.JIBJ01000015_gene2030	1.971e-33	132.0	2EK97@1|root,33DZG@2|Bacteria,2GXZX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7694140_1	1077972.ARGLB_085_00440	3.096e-177	558.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria,1WAZK@1268|Micrococcaceae	201174|Actinobacteria	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
HKD2_k127_7698420_0	1101188.KI912155_gene2088	7.582e-80	277.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PKD,Stig1
HKD2_k127_7698420_1	290399.Arth_3840	2.265e-71	259.0	COG1974@1|root,COG1974@2|Bacteria,2GPJI@201174|Actinobacteria,1W9XM@1268|Micrococcaceae	201174|Actinobacteria	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
HKD2_k127_7698420_2	452863.Achl_0220	4.343e-25	104.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,1W8SK@1268|Micrococcaceae	201174|Actinobacteria	L	Domain of unknown function (DUF4113)	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
HKD2_k127_7703695_2	1150398.JIBJ01000014_gene2405	9.406e-106	347.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HKD2_k127_7703695_5	1449044.JMLE01000017_gene1345	4.306e-74	250.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,1W9FA@1268|Micrococcaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
HKD2_k127_7703695_4	1150398.JIBJ01000014_gene2407	6.697e-82	276.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,1W9G2@1268|Micrococcaceae	201174|Actinobacteria	T	Forkhead associated domain	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
HKD2_k127_7703695_0	1449044.JMLE01000017_gene1347	4.727e-134	437.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,1W9BZ@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
HKD2_k127_7703695_3	1150398.JIBJ01000014_gene2409	1.122e-98	326.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,1W9B4@1268|Micrococcaceae	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
HKD2_k127_7703695_1	1150398.JIBJ01000014_gene2410	2.565e-120	387.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,1W7XU@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD2_k127_7733683_1	1349820.M707_03610	2.649e-125	402.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,1W7QJ@1268|Micrococcaceae	201174|Actinobacteria	C	methylmalonate-semialdehyde dehydrogenase	mmsA	GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_7733683_0	290399.Arth_0419	1.267e-167	529.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,1W7TS@1268|Micrococcaceae	201174|Actinobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD2_k127_7733683_2	1150398.JIBJ01000002_gene1128	7.563e-113	376.0	2BPHM@1|root,32IA4@2|Bacteria,2GM2J@201174|Actinobacteria,1W92Z@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7741370_2	1150398.JIBJ01000005_gene3166	3.413e-26	110.0	COG0715@1|root,COG0715@2|Bacteria,2GK7X@201174|Actinobacteria,1W8D5@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
HKD2_k127_7741370_1	1121924.ATWH01000006_gene1971	7.872e-71	247.0	2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria,4FPBZ@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7741370_0	290399.Arth_3122	1.33e-103	338.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,1W8W6@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
HKD2_k127_7744072_6	1349820.M707_15525	4.4e-23	98.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,1W8PW@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.5.1.54	ko:K01626,ko:K16019	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01051,map01100,map01110,map01130,map01230,map02024	M00022	R01826,R06591	RC00435,RC01556	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2178c	DAHP_synth_2
HKD2_k127_7744072_0	1150398.JIBJ01000014_gene2420	0.0	1043.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,1W808@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HKD2_k127_7744072_2	1449044.JMLE01000017_gene1360	6.668e-193	612.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2IBV1@201174|Actinobacteria,1W7WW@1268|Micrococcaceae	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
HKD2_k127_7744072_4	1150398.JIBJ01000014_gene2422	4.052e-61	211.0	2E0H9@1|root,32W34@2|Bacteria,2IHPW@201174|Actinobacteria,1W9QD@1268|Micrococcaceae	201174|Actinobacteria	S	transcriptional regulator	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010565,GO:0016310,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7744072_1	1150398.JIBJ01000014_gene2423	6.597e-199	624.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,1W86P@1268|Micrococcaceae	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD2_k127_7744072_5	290399.Arth_1558	6.612e-53	192.0	2DSRG@1|root,33H6C@2|Bacteria,2H0QX@201174|Actinobacteria,1WBJT@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7744072_3	1150398.JIBJ01000014_gene2425	4.068e-121	392.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,1W7S7@1268|Micrococcaceae	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
HKD2_k127_7744506_5	1150398.JIBJ01000020_gene3797	1.176e-59	208.0	COG1309@1|root,COG1309@2|Bacteria,2IQNP@201174|Actinobacteria,1W99M@1268|Micrococcaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_7744506_0	1150398.JIBJ01000020_gene3798	5.565e-241	754.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,1W8UR@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
HKD2_k127_7744506_2	1150398.JIBJ01000020_gene3799	1.945e-82	276.0	COG0783@1|root,COG0783@2|Bacteria,2IFDP@201174|Actinobacteria,1W91X@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
HKD2_k127_7744506_1	1150398.JIBJ01000020_gene3800	3.658e-131	424.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD2_k127_7744506_6	1150398.JIBJ01000020_gene3802	1.002e-31	127.0	COG1551@1|root,COG1551@2|Bacteria,2GRPH@201174|Actinobacteria	201174|Actinobacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
HKD2_k127_7744506_3	1150398.JIBJ01000020_gene3803	3.349e-77	266.0	2DHM9@1|root,32U9E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7768897_0	1150398.JIBJ01000005_gene3124	1.487e-119	396.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD2_k127_7768897_1	1150398.JIBJ01000005_gene3123	3.524e-17	81.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,1W7GV@1268|Micrococcaceae	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD2_k127_7774861_4	1194165.CAJF01000017_gene3561	1.563e-36	139.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria,4FRT4@85023|Microbacteriaceae	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HKD2_k127_7774861_1	1194165.CAJF01000017_gene3562	4.147e-159	509.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,4FKMK@85023|Microbacteriaceae	201174|Actinobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
HKD2_k127_7774861_0	1177594.MIC448_1100042	2.912e-276	853.0	COG0404@1|root,COG0404@2|Bacteria,2GPU4@201174|Actinobacteria,4FRKK@85023|Microbacteriaceae	201174|Actinobacteria	E	Aminomethyltransferase folate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
HKD2_k127_7774861_2	1177594.MIC448_1100043	2.311e-90	305.0	COG1695@1|root,COG1695@2|Bacteria,2I997@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
HKD2_k127_7774861_3	1194165.CAJF01000011_gene1108	5.231e-37	140.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
HKD2_k127_7775331_0	290399.Arth_3445	5.599e-165	524.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
HKD2_k127_7775331_1	1150398.JIBJ01000012_gene2056	1.316e-157	499.0	COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,1W8E5@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
HKD2_k127_7777282_2	105425.BBPL01000055_gene5552	2.716e-22	100.0	COG3293@1|root,COG3293@2|Bacteria,2GMT0@201174|Actinobacteria,2NFP7@228398|Streptacidiphilus	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
HKD2_k127_7777282_1	1123320.KB889716_gene7686	3.053e-30	125.0	2BHEB@1|root,32BGC@2|Bacteria,2GTIS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7777282_0	1299327.I546_7209	7.523e-286	895.0	COG0582@1|root,COG0582@2|Bacteria,2I8Z3@201174|Actinobacteria,236MD@1762|Mycobacteriaceae	201174|Actinobacteria	L	Phage integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD2_k127_7786076_4	1077972.ARGLB_010_00440	1.858e-58	203.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,1W841@1268|Micrococcaceae	201174|Actinobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
HKD2_k127_7786076_2	1349820.M707_05875	7.632e-89	296.0	COG0705@1|root,COG0705@2|Bacteria,2HCGE@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD2_k127_7786076_1	1449044.JMLE01000007_gene1210	3.967e-101	330.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,1W98J@1268|Micrococcaceae	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD2_k127_7786076_3	1150398.JIBJ01000006_gene3591	1.033e-61	216.0	2DRBP@1|root,33B4I@2|Bacteria,2GRH6@201174|Actinobacteria,1WAD8@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4307
HKD2_k127_7786076_0	1150398.JIBJ01000006_gene3590	7.529e-175	556.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,1W7GB@1268|Micrococcaceae	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
HKD2_k127_7786076_6	1158050.KB895456_gene1916	1.214e-26	114.0	28XBN@1|root,2ZJ9I@2|Bacteria,2GY64@201174|Actinobacteria,1WA95@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7786076_5	1150398.JIBJ01000006_gene3588	1.688e-42	160.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,1W7EU@1268|Micrococcaceae	201174|Actinobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HKD2_k127_7790137_2	1150398.JIBJ01000005_gene3389	8.848e-90	303.0	COG1112@1|root,COG1196@1|root,COG1112@2|Bacteria,COG1196@2|Bacteria,2GKJW@201174|Actinobacteria,1W85U@1268|Micrococcaceae	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011
HKD2_k127_7790137_4	1150398.JIBJ01000005_gene3390	1.704e-79	273.0	COG3745@1|root,COG3745@2|Bacteria,2GQJH@201174|Actinobacteria,1WA6R@1268|Micrococcaceae	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,RcpC,SAF
HKD2_k127_7790137_6	1150398.JIBJ01000005_gene3391	2.003e-38	144.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,1WA3U@1268|Micrococcaceae	201174|Actinobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
HKD2_k127_7790137_5	1150398.JIBJ01000005_gene3392	1.24e-71	248.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,1W9K2@1268|Micrococcaceae	201174|Actinobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HKD2_k127_7790137_0	1150398.JIBJ01000005_gene3393	6.353e-180	565.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria,1W7TF@1268|Micrococcaceae	201174|Actinobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD2_k127_7790137_1	1150398.JIBJ01000005_gene3394	2.601e-121	391.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,1W8YQ@1268|Micrococcaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HKD2_k127_7790137_3	1150398.JIBJ01000005_gene3395	3.364e-85	291.0	2EEES@1|root,3388S@2|Bacteria,2GSIB@201174|Actinobacteria,1W9F6@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7790312_7	1223545.GS4_26_00370	9.988e-32	127.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	marR5	-	-	-	-	-	-	-	-	-	-	-	HTH_34
HKD2_k127_7790312_6	754252.PFREUD_11190	1.024e-42	162.0	2B48T@1|root,31X00@2|Bacteria,2GY61@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7790312_0	290399.Arth_1275	0.0	1395.0	COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,1W7K8@1268|Micrococcaceae	201174|Actinobacteria	D	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
HKD2_k127_7790312_2	1150398.JIBJ01000006_gene3501	4.634e-95	316.0	COG1309@1|root,COG1309@2|Bacteria,2HGU2@201174|Actinobacteria,1W9B2@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_7790312_4	1101188.KI912155_gene2525	1.677e-57	201.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,1WB9D@1268|Micrococcaceae	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD2_k127_7790312_3	452863.Achl_1321	3.411e-61	216.0	2DIQ5@1|root,32UBF@2|Bacteria,2IMKR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7790312_1	290399.Arth_1278	5.684e-260	806.0	COG1301@1|root,COG1301@2|Bacteria,2GK6U@201174|Actinobacteria,1W7KR@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
HKD2_k127_7790312_5	1283287.KB822577_gene3087	4.255e-57	200.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4DRSQ@85009|Propionibacteriales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7790423_0	1449044.JMLE01000004_gene2455	1.286e-117	383.0	COG0749@1|root,COG0749@2|Bacteria,2GM8R@201174|Actinobacteria,1W7NX@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase	polA2	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A
HKD2_k127_7790423_1	1077972.ARGLB_008_01400	1.094e-112	373.0	COG0455@1|root,COG0455@2|Bacteria,2GIVN@201174|Actinobacteria,1W9WT@1268|Micrococcaceae	201174|Actinobacteria	D	bacterial-type flagellum organization	cpaE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CbiA
HKD2_k127_7792620_1	1150398.JIBJ01000017_gene1425	6.812e-121	395.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,1W8IU@1268|Micrococcaceae	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HKD2_k127_7792620_0	1150398.JIBJ01000017_gene1426	1.897e-135	434.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,1W86I@1268|Micrococcaceae	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HKD2_k127_7792620_2	452863.Achl_2240	2.474e-34	132.0	COG0333@1|root,COG0333@2|Bacteria,2HT7Q@201174|Actinobacteria,1W9PQ@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HKD2_k127_7803714_1	290399.Arth_1337	6.363e-43	156.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,1W7KN@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
HKD2_k127_7803714_0	1150398.JIBJ01000006_gene3446	0.0	1143.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,1W7DS@1268|Micrococcaceae	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
HKD2_k127_7809110_0	290399.Arth_0718	4.2e-134	429.0	COG0626@1|root,COG0626@2|Bacteria,2GMD8@201174|Actinobacteria,1W83S@1268|Micrococcaceae	201174|Actinobacteria	E	cystathionine gamma-synthase	metB	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
HKD2_k127_7809110_2	290399.Arth_0719	4.255e-57	200.0	2EHMU@1|root,33BDI@2|Bacteria,2HZH7@201174|Actinobacteria,1WABZ@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
HKD2_k127_7809110_1	1115632.JAFW01000001_gene3155	4.491e-94	310.0	COG4122@1|root,COG4122@2|Bacteria,2GK2F@201174|Actinobacteria,1W83F@1268|Micrococcaceae	201174|Actinobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7834468_3	1115632.JAFW01000001_gene2623	7.604e-55	192.0	COG0500@1|root,COG0500@2|Bacteria,2I3YC@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HKD2_k127_7834468_0	1151118.KB895787_gene1370	2.3e-95	327.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,1W959@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	tcsS2	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
HKD2_k127_7834468_1	1151118.KB895787_gene1369	2.231e-89	300.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,1W8YJ@1268|Micrococcaceae	201174|Actinobacteria	T	Response regulators are key elements in two-component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD2_k127_7834468_2	1151118.KB895787_gene1368	9.334e-74	259.0	2BG8A@1|root,32A59@2|Bacteria,2HTRI@201174|Actinobacteria,1WC60@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7835492_2	1449044.JMLE01000001_gene3700	4.426e-68	233.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,1WC8Z@1268|Micrococcaceae	201174|Actinobacteria	EK	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
HKD2_k127_7835492_0	290399.Arth_2517	1.865e-277	854.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,1W7VW@1268|Micrococcaceae	201174|Actinobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD2_k127_7835492_1	290399.Arth_2516	7.669e-98	332.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,1W9BW@1268|Micrococcaceae	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD2_k127_7838446_5	1132441.KI519454_gene2267	6.645e-12	70.0	COG1028@1|root,COG1028@2|Bacteria,2GJVU@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_7838446_0	1150398.JIBJ01000010_gene476	6.659e-226	703.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,1W898@1268|Micrococcaceae	201174|Actinobacteria	H	The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HKD2_k127_7838446_1	290399.Arth_2775	2.815e-120	397.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,1W93Q@1268|Micrococcaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_7838446_4	1077972.ARGLB_085_01980	4.147e-31	124.0	2E3M2@1|root,32YJA@2|Bacteria,2GQQW@201174|Actinobacteria,1WACH@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
HKD2_k127_7838446_3	1150398.JIBJ01000010_gene473	2.856e-42	158.0	2AZA7@1|root,31RHE@2|Bacteria,2H9NY@201174|Actinobacteria,1WBTJ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7838446_2	452863.Achl_1037	1.821e-57	204.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD2_k127_7846587_4	1435356.Y013_03875	1.433e-75	256.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria,4FW3R@85025|Nocardiaceae	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
HKD2_k127_7846587_3	1206739.BAGJ01000176_gene3068	9.35e-98	329.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4FZ49@85025|Nocardiaceae	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HKD2_k127_7846587_2	1206739.BAGJ01000176_gene3069	3.221e-114	374.0	COG1414@1|root,COG1414@2|Bacteria,2IBGJ@201174|Actinobacteria,4FWZU@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_7846587_1	426716.JOAJ01000009_gene6029	1.561e-204	647.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4FZJN@85025|Nocardiaceae	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
HKD2_k127_7846587_0	1206726.BAFV01000073_gene5121	4.389e-223	698.0	COG0044@1|root,COG0044@2|Bacteria,2GKEC@201174|Actinobacteria,4FWD5@85025|Nocardiaceae	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.3,3.5.2.5	ko:K01464,ko:K01465,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00051,M00546	R01993,R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
HKD2_k127_7852545_1	1449044.JMLE01000001_gene3925	1.817e-191	597.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,1W7I4@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HKD2_k127_7852545_0	290399.Arth_2248	0.0	1000.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,1W7NV@1268|Micrococcaceae	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HKD2_k127_7852545_2	290399.Arth_2249	4.343e-149	474.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,1W7QT@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
HKD2_k127_7852545_3	290399.Arth_2250	2.103e-114	371.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,1W8QW@1268|Micrococcaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HKD2_k127_7854027_1	1150398.JIBJ01000014_gene2375	3.334e-150	475.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,1W88K@1268|Micrococcaceae	201174|Actinobacteria	S	2-methylcitrate dehydratase	prpD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
HKD2_k127_7854027_0	1151119.KB895518_gene2612	6.083e-183	574.0	COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,1W7IE@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
HKD2_k127_7854027_2	1158050.KB895467_gene3285	2.922e-23	100.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,1W7RE@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	prpC	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0071704	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD2_k127_7860533_0	465541.ATCJ01000005_gene691	7.725e-160	513.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
HKD2_k127_7860533_1	298653.Franean1_5357	9.836e-10	59.0	28IHG@1|root,2Z8IP@2|Bacteria,2ID5Q@201174|Actinobacteria,4EUV6@85013|Frankiales	201174|Actinobacteria	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
HKD2_k127_7863039_9	1449044.JMLE01000013_gene2668	9.822e-05	47.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,1W7JW@1268|Micrococcaceae	201174|Actinobacteria	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD2_k127_7863039_3	1449044.JMLE01000013_gene2667	1.467e-136	437.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,1W8V6@1268|Micrococcaceae	201174|Actinobacteria	K	Helix-turn-helix diphteria tox regulatory element	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD2_k127_7863039_4	1150398.JIBJ01000018_gene2216	2.372e-124	405.0	COG0739@1|root,COG0739@2|Bacteria,2IT6R@201174|Actinobacteria,1W9X7@1268|Micrococcaceae	201174|Actinobacteria	M	peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD2_k127_7863039_5	1150398.JIBJ01000018_gene2215	5.151e-116	377.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HKD2_k127_7863039_6	1150398.JIBJ01000018_gene2214	4.7e-104	338.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,1W8YF@1268|Micrococcaceae	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
HKD2_k127_7863039_7	1077972.ARGLB_083_01820	3.844e-69	240.0	COG0746@1|root,COG0746@2|Bacteria,2GJVE@201174|Actinobacteria,1W9S9@1268|Micrococcaceae	201174|Actinobacteria	H	MobA-like NTP transferase domain	mobA	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
HKD2_k127_7863039_8	1150398.JIBJ01000018_gene2212	7.748e-39	153.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HKD2_k127_7863039_1	1150398.JIBJ01000018_gene2211	1.095e-224	708.0	COG0303@1|root,COG0303@2|Bacteria,2GP1B@201174|Actinobacteria,1W8QS@1268|Micrococcaceae	201174|Actinobacteria	H	Probable molybdopterin binding domain	moaA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HKD2_k127_7863039_2	1150398.JIBJ01000018_gene2210	5.814e-159	507.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,1W8DX@1268|Micrococcaceae	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD2_k127_7863039_0	1151119.KB895492_gene1580	0.0	1151.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,1W7JA@1268|Micrococcaceae	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
HKD2_k127_7864260_1	1449044.JMLE01000004_gene2461	1.786e-35	140.0	2EGB2@1|root,33A2X@2|Bacteria	2|Bacteria	-	-	-	GO:0008150,GO:0010941,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044531,GO:0044532,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0060548,GO:0065007	-	-	-	-	-	-	-	-	-	-	TadE
HKD2_k127_7864260_2	1197706.AKKK01000022_gene2336	4.124e-25	114.0	2DRBM@1|root,33B4F@2|Bacteria	2|Bacteria	S	TIGRFAM helicase secretion neighborhood TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
HKD2_k127_7864260_0	1150398.JIBJ01000024_gene3921	2.44e-111	361.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,1W7HY@1268|Micrococcaceae	201174|Actinobacteria	L	helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
HKD2_k127_7869139_0	1349767.GJA_5476	3.017e-28	126.0	COG3385@1|root,COG3385@2|Bacteria,1R5MG@1224|Proteobacteria,2WFGK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7869139_1	1210884.HG799462_gene8568	3.156e-05	56.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HKD2_k127_7870011_7	290399.Arth_1580	1.318e-15	79.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,1W7MK@1268|Micrococcaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD2_k127_7870011_3	290399.Arth_1579	2.734e-91	305.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,1W976@1268|Micrococcaceae	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HKD2_k127_7870011_0	1150398.JIBJ01000014_gene2444	2.181e-103	340.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,1W9BV@1268|Micrococcaceae	201174|Actinobacteria	D	DivIVA protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
HKD2_k127_7870011_6	452863.Achl_1578	1.062e-40	152.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,1W9V9@1268|Micrococcaceae	201174|Actinobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
HKD2_k127_7870011_1	290399.Arth_1576	4.152e-97	319.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,1W9K3@1268|Micrococcaceae	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HKD2_k127_7870011_2	1150398.JIBJ01000014_gene2441	1.763e-96	322.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,1W92A@1268|Micrococcaceae	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD2_k127_7870011_4	290399.Arth_1574	1.659e-89	302.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,1W94Y@1268|Micrococcaceae	201174|Actinobacteria	S	Multi-copper polyphenol oxidoreductase laccase	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HKD2_k127_7870011_5	1150398.JIBJ01000014_gene2439	3.727e-44	162.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,1W8CK@1268|Micrococcaceae	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HKD2_k127_7875867_1	290340.AAur_2522	4e-73	247.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,1W7UR@1268|Micrococcaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_7875867_0	1150398.JIBJ01000015_gene1944	1.19e-189	599.0	COG0477@1|root,COG0477@2|Bacteria,2GKQH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_7876050_0	1449044.JMLE01000002_gene4313	4.1e-157	496.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,1W7ZM@1268|Micrococcaceae	201174|Actinobacteria	F	IMP dehydrogenase family protein	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
HKD2_k127_7876050_3	452863.Achl_2583	1.625e-93	311.0	2C62X@1|root,2ZEWS@2|Bacteria,2HAF1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7876050_4	1151119.KB895490_gene2236	1.576e-78	271.0	2A4DI@1|root,30SZC@2|Bacteria,2GJJM@201174|Actinobacteria,1W94G@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7876050_1	930171.Asphe3_27200	2.662e-148	470.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,1WBE0@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
HKD2_k127_7884546_4	290340.AAur_0316	1.341e-12	68.0	COG1846@1|root,COG1846@2|Bacteria,2IKTI@201174|Actinobacteria,1W9DT@1268|Micrococcaceae	201174|Actinobacteria	K	Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_7884546_3	1150398.JIBJ01000002_gene1123	4.337e-139	453.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,1W859@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA8	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD2_k127_7884546_2	1449044.JMLE01000035_gene473	5.987e-157	500.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,1W8GG@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
HKD2_k127_7884546_1	1150398.JIBJ01000002_gene1125	1.854e-163	531.0	COG1024@1|root,COG1024@2|Bacteria,2GMET@201174|Actinobacteria,1W81X@1268|Micrococcaceae	201174|Actinobacteria	I	enoyl-CoA hydratase	echA9	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
HKD2_k127_7884546_0	1150398.JIBJ01000002_gene1126	7.897e-186	582.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,1W7QJ@1268|Micrococcaceae	201174|Actinobacteria	C	methylmalonate-semialdehyde dehydrogenase	mmsA	GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_7901176_0	105422.BBPM01000098_gene5214	5.499e-262	823.0	COG1961@1|root,COG1961@2|Bacteria,2INJA@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD2_k127_7901176_1	1108045.GORHZ_109_00020	1.616e-129	428.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
HKD2_k127_7901176_3	1108045.GORHZ_203_00030	2.716e-35	139.0	2C62F@1|root,335K1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7901176_2	1121877.JQKF01000006_gene925	1.294e-52	192.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
HKD2_k127_7909910_3	290399.Arth_2066	4.157e-60	211.0	COG5579@1|root,COG5579@2|Bacteria,2IM9J@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
HKD2_k127_7909910_1	1304876.AZVC01000002_gene878	3.375e-308	946.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,1W80Z@1268|Micrococcaceae	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HKD2_k127_7909910_2	452863.Achl_1803	7.349e-180	572.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,1W8V2@1268|Micrococcaceae	201174|Actinobacteria	S	Sterol carrier protein domain	eis	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
HKD2_k127_7909910_0	1150398.JIBJ01000004_gene3005	0.0	1090.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,1W7EA@1268|Micrococcaceae	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD2_k127_7925338_1	1463855.JOHV01000010_gene5594	3.7e-65	229.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria	201174|Actinobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_7925338_2	1223523.H340_06776	2.267e-12	78.0	COG3837@1|root,COG3837@2|Bacteria,2IRJR@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD2_k127_7925338_0	1123024.AUII01000033_gene1399	3.483e-68	237.0	COG2197@1|root,COG2197@2|Bacteria,2IBK0@201174|Actinobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
HKD2_k127_7936051_1	1150398.JIBJ01000006_gene3493	1.045e-106	347.0	COG1028@1|root,COG1028@2|Bacteria,2GIRG@201174|Actinobacteria,1W84V@1268|Micrococcaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short,adh_short_C2
HKD2_k127_7936051_0	1150398.JIBJ01000006_gene3492	4.199e-159	505.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,1W9TT@1268|Micrococcaceae	201174|Actinobacteria	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
HKD2_k127_7937591_0	379066.GAU_1611	6.173e-26	111.0	COG0253@1|root,COG0253@2|Bacteria,1ZU42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD2_k127_7937591_1	1122222.AXWR01000004_gene1772	1.042e-09	68.0	2CVD4@1|root,32SXD@2|Bacteria,1WMZT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7951676_0	1210884.HG799477_gene15428	8.524e-118	391.0	28JEU@1|root,2Z98W@2|Bacteria	2|Bacteria	S	PFAM MULE transposase, conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	MULE,Transposase_mut
HKD2_k127_7951676_1	1217720.ALOX01000142_gene3559	5.02e-57	207.0	2ED3F@1|root,3370B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7951676_2	1210884.HG799464_gene10857	4.619e-09	57.0	COG3415@1|root,COG3415@2|Bacteria,2J0C8@203682|Planctomycetes	2|Bacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
HKD2_k127_7960830_2	1077972.ARGLB_073_00310	5.303e-05	47.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
HKD2_k127_7960830_0	1158050.KB895461_gene2925	4.75e-141	460.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_7C,Glycos_transf_2
HKD2_k127_7960830_1	1158050.KB895461_gene2926	3.178e-65	234.0	COG1215@1|root,COG1215@2|Bacteria,2I2NS@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_7969511_3	1150398.JIBJ01000009_gene346	2.891e-47	173.0	COG3290@1|root,COG3290@2|Bacteria,2GIRZ@201174|Actinobacteria,1W8SW@1268|Micrococcaceae	201174|Actinobacteria	T	Signal transduction histidine kinase regulating citrate malate metabolism	-	-	2.7.13.3	ko:K02476	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,PAS_4,PAS_8,SPOB_a,sCache_3_2
HKD2_k127_7969511_0	1150398.JIBJ01000009_gene347	1.811e-180	570.0	COG3181@1|root,COG3181@2|Bacteria,2GJ89@201174|Actinobacteria,1W8WP@1268|Micrococcaceae	201174|Actinobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
HKD2_k127_7969511_2	1150398.JIBJ01000009_gene348	9.165e-83	295.0	293R6@1|root,2ZR6U@2|Bacteria,2HRYX@201174|Actinobacteria	201174|Actinobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
HKD2_k127_7969511_1	1150398.JIBJ01000009_gene349	5.068e-95	315.0	COG3333@1|root,COG3333@2|Bacteria,2GJB2@201174|Actinobacteria,1W7VZ@1268|Micrococcaceae	201174|Actinobacteria	S	Tripartite tricarboxylate transporter TctA family	tctA	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
HKD2_k127_8018412_1	290399.Arth_2700	2.089e-76	259.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,1W8IX@1268|Micrococcaceae	201174|Actinobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
HKD2_k127_8018412_0	1150398.JIBJ01000010_gene544	0.0	1266.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,1W7V1@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
HKD2_k127_8020238_1	1150398.JIBJ01000007_gene60	6.757e-151	495.0	COG0609@1|root,COG0609@2|Bacteria,2GJB9@201174|Actinobacteria,1W90U@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HKD2_k127_8020238_0	1158050.KB895475_gene2811	1.677e-167	533.0	COG0614@1|root,COG0614@2|Bacteria,2IA3G@201174|Actinobacteria,1W7K2@1268|Micrococcaceae	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HKD2_k127_8020468_1	345341.KUTG_09476	1.777e-07	56.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4E13H@85010|Pseudonocardiales	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_8020468_0	1089545.KB913037_gene4736	1.733e-116	391.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4E8AR@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HKD2_k127_8031991_5	290399.Arth_1246	2.09e-34	132.0	COG1988@1|root,COG1988@2|Bacteria,2GMNG@201174|Actinobacteria,1W9V2@1268|Micrococcaceae	201174|Actinobacteria	S	membrane-bound metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
HKD2_k127_8031991_6	1151119.KB895495_gene2306	3.23e-28	117.0	2B3MN@1|root,31WB1@2|Bacteria,2GWYW@201174|Actinobacteria,1WAA2@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8031991_2	290399.Arth_1248	5.64e-122	395.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,1W8DB@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD2_k127_8031991_1	1150398.JIBJ01000006_gene3525	3.619e-134	435.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nasA	-	1.6.99.3,1.7.7.2	ko:K00367,ko:K00372,ko:K03885	ko00190,ko00910,ko01120,map00190,map00910,map01120	M00531	R00791,R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
HKD2_k127_8031991_0	1150398.JIBJ01000006_gene3524	1.324e-202	654.0	COG0745@1|root,COG1587@1|root,COG0745@2|Bacteria,COG1587@2|Bacteria,2GKMM@201174|Actinobacteria,1W8PZ@1268|Micrococcaceae	201174|Actinobacteria	HKT	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Trans_reg_C
HKD2_k127_8031991_3	1132441.KI519454_gene245	1.536e-108	367.0	COG0007@1|root,COG0007@2|Bacteria,2GK3B@201174|Actinobacteria,1W93A@1268|Micrococcaceae	201174|Actinobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
HKD2_k127_8031991_4	1151119.KB895495_gene2301	4.603e-62	215.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,1W8TN@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
HKD2_k127_8034580_2	1150398.JIBJ01000023_gene3879	9.579e-292	899.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,1W84P@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	novA1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_8034580_0	290399.Arth_0854	0.0	1056.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,1W8GZ@1268|Micrococcaceae	201174|Actinobacteria	EGP	drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_8034580_4	1150398.JIBJ01000023_gene3881	4.425e-70	247.0	COG1846@1|root,COG1846@2|Bacteria,2IFZ3@201174|Actinobacteria,1WCKN@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_8034580_1	1449044.JMLE01000022_gene1466	0.0	1052.0	COG0028@1|root,COG0028@2|Bacteria,2GKQM@201174|Actinobacteria,1W8I6@1268|Micrococcaceae	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvB4	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD2_k127_8034580_3	1101188.KI912155_gene2253	8.911e-217	674.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,1W7Z5@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the arginase family	gbh	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD2_k127_8040366_0	290399.Arth_0215	5.129e-222	705.0	COG2072@1|root,COG2072@2|Bacteria,2GKBD@201174|Actinobacteria,1WCE9@1268|Micrococcaceae	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
HKD2_k127_8040366_2	1150398.JIBJ01000022_gene3757	3.92e-68	250.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,1W979@1268|Micrococcaceae	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD2_k127_8040366_1	290399.Arth_0212	6.685e-206	644.0	COG0798@1|root,COG0798@2|Bacteria,2GJ4H@201174|Actinobacteria,1W8VQ@1268|Micrococcaceae	201174|Actinobacteria	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
HKD2_k127_8040570_1	1423754.BALY01000014_gene142	4.584e-09	62.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_8040570_0	1499967.BAYZ01000110_gene3008	1.554e-55	208.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,rve,rve_3
HKD2_k127_8058497_2	1150398.JIBJ01000014_gene2448	7.705e-64	229.0	COG5343@1|root,COG5343@2|Bacteria,2IM7X@201174|Actinobacteria	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
HKD2_k127_8058497_1	1132441.KI519455_gene3683	1.327e-138	469.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,1W9AJ@1268|Micrococcaceae	201174|Actinobacteria	C	oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD2_k127_8058497_0	290399.Arth_3779	2.2e-168	538.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria,1W8UM@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_8058497_4	644548.SCNU_13774	1.901e-13	72.0	2B5RK@1|root,31YM5@2|Bacteria,2I01V@201174|Actinobacteria,4GFIY@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8058497_3	290399.Arth_0211	4.926e-43	158.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,1W9FK@1268|Micrococcaceae	201174|Actinobacteria	K	arsR family	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
HKD2_k127_8078549_1	290399.Arth_0547	1.825e-55	200.0	2BYGI@1|root,333FU@2|Bacteria	2|Bacteria	S	Strong inhibitor of bacterial serine proteases such as subtilisin	-	-	-	-	-	-	-	-	-	-	-	-	SSI
HKD2_k127_8078549_0	1150398.JIBJ01000002_gene1029	4.648e-165	526.0	2BYH3@1|root,2Z7SZ@2|Bacteria,2GMTF@201174|Actinobacteria,1W7DW@1268|Micrococcaceae	201174|Actinobacteria	S	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8088578_2	867903.ThesuDRAFT_01275	7.848e-37	158.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,3WD6V@538999|Clostridiales incertae sedis	186801|Clostridia	C	acyl-CoA transferase carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HKD2_k127_8088578_0	1380347.JNII01000006_gene1939	9.649e-171	547.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4ESHG@85013|Frankiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08172	-	-	-	-	ko00000,ko02000	2.A.1.6.6	-	-	MFS_1,Sugar_tr
HKD2_k127_8088578_1	930171.Asphe3_10490	1.541e-78	267.0	COG1414@1|root,COG1414@2|Bacteria,2HFKK@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_8092337_3	1150398.JIBJ01000006_gene3685	5.05e-29	116.0	2EF7K@1|root,3390K@2|Bacteria,2GQM6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8092337_0	290399.Arth_1073	2.669e-245	767.0	COG2268@1|root,COG2268@2|Bacteria,2GK9I@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Flot
HKD2_k127_8092337_2	290399.Arth_1084	9.118e-81	273.0	2C9IE@1|root,31AT3@2|Bacteria,2IM6M@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
HKD2_k127_8092337_1	1077972.ARGLB_065_00130	2.046e-163	520.0	COG3266@1|root,COG3266@2|Bacteria,2I39E@201174|Actinobacteria,1W7EP@1268|Micrococcaceae	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8096926_0	1150398.JIBJ01000012_gene2083	1.448e-152	503.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
HKD2_k127_8096926_2	1449044.JMLE01000012_gene3140	6.624e-30	122.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
HKD2_k127_8096926_1	452863.Achl_0325	2.812e-102	336.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,1W8YC@1268|Micrococcaceae	201174|Actinobacteria	S	Intracellular protease, PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
HKD2_k127_8118563_0	1121405.dsmv_1696	1.416e-185	593.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MHX7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
HKD2_k127_8126015_2	1077972.ARGLB_014_00110	1.343e-38	146.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD2_k127_8126015_0	290399.Arth_0522	6.423e-161	507.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,1W7UU@1268|Micrococcaceae	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD2_k127_8128871_7	1150398.JIBJ01000009_gene410	1.437e-37	142.0	COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,1W9NN@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
HKD2_k127_8128871_3	1158050.KB895468_gene3253	1.992e-79	267.0	COG1426@1|root,COG1426@2|Bacteria,2I2G5@201174|Actinobacteria,1WCMF@1268|Micrococcaceae	201174|Actinobacteria	K	helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
HKD2_k127_8128871_4	1150398.JIBJ01000009_gene412	1.135e-71	246.0	COG1846@1|root,COG1846@2|Bacteria,2IQNM@201174|Actinobacteria,1WA1R@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_8128871_6	290399.Arth_1459	7.627e-38	142.0	2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,1WA02@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
HKD2_k127_8128871_0	1150398.JIBJ01000009_gene414	2.929e-215	669.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,1W8D0@1268|Micrococcaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HKD2_k127_8128871_5	1077972.ARGLB_016_00510	1.489e-64	226.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,1W9FR@1268|Micrococcaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HKD2_k127_8128871_8	1157634.KB912980_gene1380	5.006e-33	130.0	COG1476@1|root,COG1476@2|Bacteria,2I44J@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HKD2_k127_8128871_2	1449044.JMLE01000003_gene2796	2.25e-139	445.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria	201174|Actinobacteria	J	Methionine aminopeptidase	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD2_k127_8128871_1	290399.Arth_1462	2.38e-180	566.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,1W86Z@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD2_k127_8132332_6	1158050.KB895452_gene152	8.132e-112	361.0	COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,1W8H9@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	glfT1	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008378,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.4.1.287	ko:K16649	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
HKD2_k127_8132332_2	1158050.KB895452_gene151	1.353e-166	537.0	COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_8132332_1	1158050.KB895452_gene150	0.0	1080.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,1W8XA@1268|Micrococcaceae	201174|Actinobacteria	M	CoA-binding domain	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
HKD2_k127_8132332_3	1158050.KB895452_gene149	1.537e-166	533.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,1W819@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
HKD2_k127_8132332_8	1150398.JIBJ01000015_gene2012	4.932e-68	238.0	2DSZR@1|root,33I3C@2|Bacteria,2GUCJ@201174|Actinobacteria,1WA3W@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	-
HKD2_k127_8132332_9	290399.Arth_2612	5.637e-44	164.0	COG5336@1|root,COG5336@2|Bacteria,2GS71@201174|Actinobacteria,1WCK2@1268|Micrococcaceae	201174|Actinobacteria	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8132332_4	1077972.ARGLB_085_00240	3.731e-153	486.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,1WAQD@1268|Micrococcaceae	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HKD2_k127_8132332_10	1077972.ARGLB_085_00230	3.054e-30	132.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,1WA1S@1268|Micrococcaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD2_k127_8132332_7	930171.Asphe3_24720	3.917e-85	284.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,1W8WU@1268|Micrococcaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HKD2_k127_8132332_5	1449044.JMLE01000005_gene605	1.417e-136	438.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,1W805@1268|Micrococcaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
HKD2_k127_8132332_0	1150398.JIBJ01000015_gene2007	0.0	1085.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,1W7FF@1268|Micrococcaceae	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD2_k127_8132332_11	1115632.JAFW01000001_gene659	2.644e-20	90.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,1W86S@1268|Micrococcaceae	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HKD2_k127_8140546_1	1173022.Cri9333_0577	1.054e-41	156.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_8140546_2	1385935.N836_22145	3.276e-15	79.0	COG2963@1|root,COG2963@2|Bacteria,1GAKB@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
HKD2_k127_8140546_0	102129.Lepto7375DRAFT_7503	2.559e-91	309.0	COG2801@1|root,COG2801@2|Bacteria,1G5GD@1117|Cyanobacteria,1HGQD@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
HKD2_k127_8156475_0	1151119.KB895495_gene2329	5.182e-301	929.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,1W7ZB@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_8156475_1	1150398.JIBJ01000006_gene3552	5.683e-35	143.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,1W8S0@1268|Micrococcaceae	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
HKD2_k127_8159843_3	1132441.KI519455_gene3060	5.364e-103	339.0	COG1802@1|root,COG1802@2|Bacteria,2GMZ9@201174|Actinobacteria,1W9HA@1268|Micrococcaceae	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HKD2_k127_8159843_2	1132441.KI519455_gene3059	8.207e-125	403.0	COG3819@1|root,COG3819@2|Bacteria,2GP03@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF969)	-	-	-	-	-	-	-	-	-	-	-	-	DUF969
HKD2_k127_8159843_0	1132441.KI519455_gene3058	2.566e-175	557.0	COG3817@1|root,COG3817@2|Bacteria,2I9GU@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF979)	-	-	-	-	-	-	-	-	-	-	-	-	DUF979
HKD2_k127_8159843_1	1132441.KI519455_gene3057	5.885e-155	494.0	2C57D@1|root,2Z7RS@2|Bacteria,2GNIJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
HKD2_k127_81838_1	1150398.JIBJ01000002_gene1115	8.079e-236	734.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,1WAR6@1268|Micrococcaceae	201174|Actinobacteria	T	Domain of unknown function (DUF4118)	kdpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
HKD2_k127_81838_2	1150398.JIBJ01000002_gene1114	5.072e-81	274.0	COG2156@1|root,COG2156@2|Bacteria,2GK75@201174|Actinobacteria,1W9IH@1268|Micrococcaceae	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
HKD2_k127_81838_0	1150398.JIBJ01000002_gene1113	0.0	1154.0	COG2216@1|root,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria,1W89X@1268|Micrococcaceae	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
HKD2_k127_81838_3	1158050.KB895453_gene982	6.895e-64	220.0	COG2060@1|root,COG2060@2|Bacteria,2GK51@201174|Actinobacteria,1W96F@1268|Micrococcaceae	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
HKD2_k127_8232921_3	290399.Arth_2433	2.308e-33	130.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria	201174|Actinobacteria	L	DNA alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HKD2_k127_8232921_0	290399.Arth_2434	1.124e-301	932.0	2AMJ0@1|root,31CER@2|Bacteria,2I3ZG@201174|Actinobacteria,1WCDZ@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
HKD2_k127_8232921_1	290399.Arth_2435	3.697e-115	374.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,1W94E@1268|Micrococcaceae	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
HKD2_k127_8232921_2	1150398.JIBJ01000004_gene2662	1.047e-42	162.0	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria,1W81K@1268|Micrococcaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_8259125_1	1121434.AULY01000010_gene2403	4.527e-30	121.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,42PAQ@68525|delta/epsilon subdivisions,2WKN9@28221|Deltaproteobacteria,2M9RR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
HKD2_k127_8259125_0	882082.SaccyDRAFT_1772	3.672e-45	179.0	COG3395@1|root,COG3395@2|Bacteria,2GNIH@201174|Actinobacteria,4E73F@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
HKD2_k127_8267108_1	1150398.JIBJ01000007_gene259	1.438e-15	83.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,1W7RY@1268|Micrococcaceae	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
HKD2_k127_8267108_0	1150398.JIBJ01000007_gene260	3.222e-262	812.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,1W7JX@1268|Micrococcaceae	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD2_k127_8271778_0	1158050.KB895467_gene3355	7.416e-163	512.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,1W84K@1268|Micrococcaceae	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD2_k127_8271778_2	1150398.JIBJ01000014_gene2468	2.199e-80	269.0	COG1714@1|root,COG1714@2|Bacteria,2IQMG@201174|Actinobacteria,1W9JJ@1268|Micrococcaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD2_k127_8271778_1	1449044.JMLE01000017_gene1406	3.493e-132	424.0	2AUFS@1|root,2ZA62@2|Bacteria,2I87X@201174|Actinobacteria,1W8NV@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4191
HKD2_k127_8271778_3	1150398.JIBJ01000014_gene2471	8.269e-50	177.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,1W7U8@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HKD2_k127_8298766_0	1550073.JROH01000035_gene2627	5.007e-19	101.0	COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,2U1IW@28211|Alphaproteobacteria,2K0T3@204457|Sphingomonadales	204457|Sphingomonadales	L	TrwC protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC,Viral_helicase1
HKD2_k127_8298766_1	1123023.JIAI01000055_gene2526	2.84e-11	66.0	28MWI@1|root,2ZB3T@2|Bacteria,2GRHZ@201174|Actinobacteria	201174|Actinobacteria	S	Plasmid encoded RepA protein	repW	-	-	-	-	-	-	-	-	-	-	-	RepA_C
HKD2_k127_8302501_2	1077972.ARGLB_054_00800	4.417e-85	284.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,1W8NJ@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_8302501_1	1150398.JIBJ01000006_gene3467	4.971e-203	642.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,1W7RT@1268|Micrococcaceae	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD2_k127_8302501_0	1150398.JIBJ01000006_gene3468	3.684e-272	841.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,1W7SC@1268|Micrococcaceae	201174|Actinobacteria	E	O-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD2_k127_8305780_2	1449044.JMLE01000004_gene2434	1.927e-129	417.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,1W86Q@1268|Micrococcaceae	201174|Actinobacteria	O	Colicin V production protein	cvpA	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
HKD2_k127_8305780_1	290399.Arth_3395	1.39e-135	432.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1W7T9@1268|Micrococcaceae	201174|Actinobacteria	K	Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD2_k127_8305780_0	290399.Arth_3396	3.047e-177	557.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,1W974@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_8305780_3	1150398.JIBJ01000012_gene2038	4.922e-11	62.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,1W96K@1268|Micrococcaceae	201174|Actinobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD2_k127_8330877_1	1210884.HG799470_gene14318	2.804e-19	93.0	COG5659@1|root,COG5659@2|Bacteria,2IWRG@203682|Planctomycetes	203682|Planctomycetes	L	best DB hits BLAST gb AAD45539.1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_8330877_0	886293.Sinac_2157	4.732e-223	700.0	COG3385@1|root,COG3385@2|Bacteria,2J0KK@203682|Planctomycetes	203682|Planctomycetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_8330877_2	331869.BAL199_00645	3.583e-09	63.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,4BSI7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
HKD2_k127_83370_0	1150398.JIBJ01000024_gene3934	7.087e-106	358.0	2ECJB@1|root,336HD@2|Bacteria,2GMJH@201174|Actinobacteria,1W9P5@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_83370_1	290399.Arth_3378	3.012e-34	132.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,1W8HI@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD2_k127_8339614_1	1150398.JIBJ01000004_gene2725	3.402e-84	282.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,1W8II@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	calB	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_8339614_0	290399.Arth_2365	1.469e-98	323.0	28PC3@1|root,2ZC4J@2|Bacteria,2HDQS@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2004)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2004
HKD2_k127_8339614_2	1150398.JIBJ01000004_gene2720	2.786e-34	132.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GIU4@201174|Actinobacteria,1W8AN@1268|Micrococcaceae	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
HKD2_k127_8352453_1	710111.FraQA3DRAFT_5016	1.216e-08	64.0	2FK7M@1|root,34BVC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8352453_0	710111.FraQA3DRAFT_5017	1.188e-81	287.0	COG0699@1|root,COG0699@2|Bacteria,2IMJQ@201174|Actinobacteria	201174|Actinobacteria	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Pox_A32
HKD2_k127_8382559_3	1150398.JIBJ01000002_gene893	2.535e-66	226.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,1W7EV@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	tcrX	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_8382559_0	1150398.JIBJ01000002_gene894	1.657e-249	778.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,1W8V0@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_8382559_1	1150398.JIBJ01000002_gene896	3.236e-240	751.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
HKD2_k127_8382559_2	1150398.JIBJ01000002_gene897	6.242e-87	290.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria	201174|Actinobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD2_k127_8414790_0	1150398.JIBJ01000007_gene148	1.404e-291	897.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,1W7E5@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
HKD2_k127_8414790_1	1312954.KI914852_gene638	1.753e-70	246.0	COG3568@1|root,COG3568@2|Bacteria,2H3ST@201174|Actinobacteria,1WB2R@1268|Micrococcaceae	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD2_k127_8445438_1	1150398.JIBJ01000008_gene752	7.208e-77	259.0	COG0147@1|root,COG0572@1|root,COG0147@2|Bacteria,COG0572@2|Bacteria,2GKJT@201174|Actinobacteria,1W83E@1268|Micrococcaceae	201174|Actinobacteria	EH	synthase component I	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind,GATase
HKD2_k127_8445438_0	1150398.JIBJ01000008_gene751	1.438e-81	276.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,1W9TN@1268|Micrococcaceae	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD2_k127_8445438_2	1312954.KI914878_gene1378	1.166e-65	233.0	COG0454@1|root,COG0456@2|Bacteria,2IFM6@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Condensation
HKD2_k127_8445438_4	1416752.AYME01000005_gene1640	2.298e-53	196.0	COG1309@1|root,COG1309@2|Bacteria,2IJIU@201174|Actinobacteria,4FNXM@85023|Microbacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_8445438_3	452863.Achl_1693	3.802e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,1W9WP@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD2_k127_8445438_5	66897.DJ64_03200	5.626e-53	187.0	COG3340@1|root,COG3340@2|Bacteria,2GMIV@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
HKD2_k127_8480706_2	1449044.JMLE01000008_gene2219	5.274e-65	225.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,1WC8W@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_8480706_4	930171.Asphe3_04480	1.007e-46	170.0	COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,1W9UF@1268|Micrococcaceae	201174|Actinobacteria	S	Thiamine-binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
HKD2_k127_8480706_5	1132441.KI519455_gene3565	1.246e-18	97.0	2ERT9@1|root,33JCG@2|Bacteria,2GXHB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8480706_0	1312954.KI914852_gene663	4.986e-219	702.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	epsG	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
HKD2_k127_8480706_1	1150398.JIBJ01000002_gene1183	2.724e-150	489.0	COG1960@1|root,COG1960@2|Bacteria,2GKK2@201174|Actinobacteria,1W9A7@1268|Micrococcaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_M
HKD2_k127_8480706_3	290340.AAur_3424	2.578e-64	224.0	COG0500@1|root,COG2120@1|root,COG0500@2|Bacteria,COG2120@2|Bacteria,2IA7G@201174|Actinobacteria,1W8UF@1268|Micrococcaceae	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,NodS,PIG-L
HKD2_k127_8495996_2	1150398.JIBJ01000005_gene3174	4.822e-114	373.0	2DBB1@1|root,2Z854@2|Bacteria,2GNBN@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
HKD2_k127_8495996_3	290399.Arth_3106	8.359e-89	296.0	2C7GR@1|root,32H51@2|Bacteria,2IPDA@201174|Actinobacteria,1WC70@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8495996_4	290399.Arth_3102	8.723e-54	209.0	COG2091@1|root,COG2091@2|Bacteria,2HTQ0@201174|Actinobacteria,1WC13@1268|Micrococcaceae	201174|Actinobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
HKD2_k127_8495996_1	290399.Arth_3101	2.473e-142	461.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,1W949@1268|Micrococcaceae	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
HKD2_k127_8495996_0	290399.Arth_3100	3.217e-158	504.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,1W7SX@1268|Micrococcaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD2_k127_8495996_5	452863.Achl_1745	6.944e-40	148.0	COG3251@1|root,COG3251@2|Bacteria,2GQFU@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH
HKD2_k127_8495996_6	1115632.JAFW01000001_gene4421	7.29e-24	102.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,1WCH3@1268|Micrococcaceae	201174|Actinobacteria	Q	Peptide synthetase	-	-	6.3.2.14	ko:K02364	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
HKD2_k127_8501755_2	1150398.JIBJ01000002_gene1100	4.263e-28	113.0	COG0477@1|root,COG2814@2|Bacteria,2I2P6@201174|Actinobacteria,1WAB4@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_8501755_1	1150398.JIBJ01000002_gene1101	1.531e-94	312.0	COG1309@1|root,COG1309@2|Bacteria,2HFWU@201174|Actinobacteria,1WC36@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
HKD2_k127_8501755_0	1150398.JIBJ01000002_gene1102	1.51e-208	651.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,1W8BC@1268|Micrococcaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
HKD2_k127_8520446_0	1151119.KB895501_gene2893	1.44e-306	943.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,1W7WP@1268|Micrococcaceae	201174|Actinobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
HKD2_k127_8576807_1	1150398.JIBJ01000006_gene3555	2.821e-126	414.0	COG1928@1|root,COG1928@2|Bacteria,2I2H1@201174|Actinobacteria,1W7US@1268|Micrococcaceae	201174|Actinobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	pmt	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
HKD2_k127_8576807_0	1150398.JIBJ01000006_gene3554	9.638e-144	461.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,1W7DZ@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD2_k127_8595217_1	1449044.JMLE01000046_gene2616	4.474e-156	496.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,1WB5R@1268|Micrococcaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD2_k127_8595217_0	1304876.AZVC01000010_gene2065	9.714e-222	695.0	COG4733@1|root,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,1WATK@1268|Micrococcaceae	201174|Actinobacteria	S	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
HKD2_k127_8616139_0	656024.FsymDg_1984	3.493e-88	302.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2IDYA@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Transposase IS3 IS911	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
HKD2_k127_8616139_1	1229780.BN381_250012	2.24e-80	289.0	COG3464@1|root,COG3464@2|Bacteria,2I56J@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8616139_2	1449347.JQLN01000001_gene18	1.571e-36	141.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
HKD2_k127_8639617_1	1150398.JIBJ01000003_gene1843	9.445e-28	119.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,1W89S@1268|Micrococcaceae	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
HKD2_k127_8639617_0	930171.Asphe3_16710	1.449e-313	962.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,1W7MB@1268|Micrococcaceae	201174|Actinobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD2_k127_86580_2	1150398.JIBJ01000006_gene3686	2.846e-51	183.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,1W7H1@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	mgtA	GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12583	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD2_k127_86580_0	1449044.JMLE01000007_gene1311	5.207e-217	687.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,1W7QB@1268|Micrococcaceae	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD2_k127_86580_1	1150398.JIBJ01000006_gene3687	1.449e-161	516.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8
HKD2_k127_8673602_0	1032480.MLP_17780	7.796e-26	123.0	COG3385@1|root,COG3385@2|Bacteria,2GKQB@201174|Actinobacteria,4DSZZ@85009|Propionibacteriales	201174|Actinobacteria	L	Insertion element 4 transposase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
HKD2_k127_8734896_3	1150398.JIBJ01000008_gene742	1.948e-64	228.0	2DMP1@1|root,32SS8@2|Bacteria,2INWH@201174|Actinobacteria,1WCK8@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
HKD2_k127_8734896_0	1077972.ARGLB_027_01350	7.526e-292	906.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria	201174|Actinobacteria	IQ	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD2_k127_8734896_1	1150398.JIBJ01000008_gene740	6.611e-252	783.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_8734896_2	1150398.JIBJ01000008_gene739	3.555e-154	491.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
HKD2_k127_8734896_4	290399.Arth_3817	3.919e-44	161.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria	201174|Actinobacteria	E	Lysine exporter protein (LysE YggA)	rhtB	-	-	ko:K05834	-	-	-	-	ko00000,ko02000	2.A.76.1.1	-	-	LysE
HKD2_k127_8742192_0	1158050.KB895452_gene522	5.13e-160	509.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,1W8VB@1268|Micrococcaceae	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD2_k127_8742192_1	290399.Arth_3014	4.41e-76	257.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,1W85M@1268|Micrococcaceae	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD2_k127_8834095_1	1303692.SFUL_598	3.427e-63	225.0	COG0596@1|root,COG0596@2|Bacteria,2I4JZ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
HKD2_k127_8834095_0	1151119.KB895496_gene3846	1.759e-82	281.0	COG0500@1|root,COG0500@2|Bacteria,2HFN5@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
HKD2_k127_8834095_2	1132441.KI519454_gene1447	1.118e-46	171.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE,EAL,GGDEF
HKD2_k127_8836489_1	1150398.JIBJ01000002_gene895	4.928e-67	236.0	COG4942@1|root,COG4942@2|Bacteria,2I5TS@201174|Actinobacteria	201174|Actinobacteria	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8836489_0	1150398.JIBJ01000002_gene901	9.526e-76	254.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,1W89U@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HKD2_k127_88427_4	1449044.JMLE01000007_gene1161	6.271e-27	110.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,1W8PX@1268|Micrococcaceae	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD2_k127_88427_2	1449044.JMLE01000007_gene1162	1.497e-159	506.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,1W7JH@1268|Micrococcaceae	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HKD2_k127_88427_0	290399.Arth_1212	4.525e-183	582.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,1WA71@1268|Micrococcaceae	201174|Actinobacteria	S	G5	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
HKD2_k127_88427_1	1150398.JIBJ01000006_gene3549	1.926e-163	517.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,1W8J7@1268|Micrococcaceae	201174|Actinobacteria	L	hydrolase, TatD family	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HKD2_k127_88427_3	290399.Arth_1210	5.413e-87	309.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,1W7KE@1268|Micrococcaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD2_k127_8880347_0	290399.Arth_2632	1.544e-205	642.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,1W7M5@1268|Micrococcaceae	201174|Actinobacteria	L	ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
HKD2_k127_8880347_1	929712.KI912613_gene1453	9.973e-94	329.0	COG0300@1|root,COG0300@2|Bacteria,2H30G@201174|Actinobacteria,4CQR8@84995|Rubrobacteria	84995|Rubrobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_894210_1	1150398.JIBJ01000005_gene3324	3.724e-156	496.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,1W7TI@1268|Micrococcaceae	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD2_k127_894210_0	1150398.JIBJ01000005_gene3325	1.613e-205	653.0	COG5002@1|root,COG5002@2|Bacteria,2HGIV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8
HKD2_k127_894210_2	1150398.JIBJ01000005_gene3326	2.351e-82	279.0	COG0745@1|root,COG0745@2|Bacteria,2ICPT@201174|Actinobacteria	201174|Actinobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_8944976_2	1449044.JMLE01000029_gene131	2.576e-88	291.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_8944976_1	1158050.KB895457_gene2198	6.569e-89	295.0	COG2249@1|root,COG2249@2|Bacteria	2|Bacteria	K	NAD(P)H dehydrogenase (quinone) activity	ywrO	-	1.6.5.2	ko:K00355,ko:K11748	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
HKD2_k127_8944976_0	1150398.JIBJ01000002_gene1099	1.141e-132	436.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,1W8Q3@1268|Micrococcaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD2_k127_8944976_3	1150398.JIBJ01000002_gene1100	5.37e-68	234.0	COG0477@1|root,COG2814@2|Bacteria,2I2P6@201174|Actinobacteria,1WAB4@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_8945213_3	864069.MicloDRAFT_00002930	3.905e-12	72.0	COG3335@1|root,COG3335@2|Bacteria,1MXYQ@1224|Proteobacteria,2TSX4@28211|Alphaproteobacteria,1JYEX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
HKD2_k127_8945213_2	1123508.JH636441_gene3524	2.28e-46	180.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_32
HKD2_k127_8945213_1	1210884.HG799475_gene15312	8.425e-54	194.0	COG3415@1|root,COG3415@2|Bacteria,2J3GY@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8945213_0	1210884.HG799475_gene15311	6.045e-79	274.0	COG3335@1|root,COG3335@2|Bacteria,2J2QQ@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
HKD2_k127_8945213_4	631454.N177_1898	2.157e-08	56.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
HKD2_k127_8947133_0	1150398.JIBJ01000002_gene1222	3.483e-185	587.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,1W91A@1268|Micrococcaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Phospholip_A2_3
HKD2_k127_8947133_2	1150398.JIBJ01000002_gene1221	3.064e-52	198.0	COG2388@1|root,COG2388@2|Bacteria	2|Bacteria	S	GCN5-related N-acetyl-transferase	-	-	2.7.7.7	ko:K02346,ko:K06975	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Acetyltransf_CG,CMD
HKD2_k127_8947133_1	290399.Arth_0280	5.741e-65	240.0	2BG7S@1|root,32A4P@2|Bacteria,2HTQX@201174|Actinobacteria,1WC43@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8947133_3	1150398.JIBJ01000002_gene1219	2.259e-46	169.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,1W8W2@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HKD2_k127_8967775_3	1101188.KI912155_gene884	1.106e-38	144.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,1W7S1@1268|Micrococcaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD2_k127_8967775_0	1150398.JIBJ01000005_gene3274	2.583e-243	757.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,1W82R@1268|Micrococcaceae	201174|Actinobacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_8967775_2	290399.Arth_2996	1.013e-43	163.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,1W9P4@1268|Micrococcaceae	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HKD2_k127_8967775_1	1304876.AZVC01000001_gene1283	4.725e-146	466.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,1W89Q@1268|Micrococcaceae	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
HKD2_k127_8967775_4	1101188.KI912155_gene880	2.352e-33	128.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,1W8YY@1268|Micrococcaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HKD2_k127_8988330_1	1151118.KB895799_gene567	5.578e-66	229.0	COG1595@1|root,COG1595@2|Bacteria,2GSY2@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_8988330_2	1150398.JIBJ01000014_gene2372	6.336e-56	196.0	COG1051@1|root,COG1051@2|Bacteria,2INIJ@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD2_k127_9001498_0	1150398.JIBJ01000017_gene1417	4.813e-261	806.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,1W88D@1268|Micrococcaceae	201174|Actinobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HKD2_k127_9001498_1	1150398.JIBJ01000017_gene1418	2.718e-212	668.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,1W7XF@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_9001498_2	290399.Arth_2494	1.024e-191	600.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,1W899@1268|Micrococcaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD2_k127_9003997_2	448385.sce1662	1.715e-17	84.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2YU89@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
HKD2_k127_9003997_0	933262.AXAM01000013_gene1287	6.517e-141	457.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2MIUK@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD2_k127_9003997_1	933262.AXAM01000013_gene1288	8.064e-60	226.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MHZT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD2_k127_9005205_4	1048339.KB913029_gene4385	0.0007747	43.0	2CNY9@1|root,31GEE@2|Bacteria,2IKKZ@201174|Actinobacteria,4ET09@85013|Frankiales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
HKD2_k127_9005205_3	1150398.JIBJ01000004_gene3033	5.891e-140	448.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,1W97T@1268|Micrococcaceae	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
HKD2_k127_9005205_2	290399.Arth_2093	7.736e-185	580.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,1W7RV@1268|Micrococcaceae	201174|Actinobacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
HKD2_k127_9005205_0	290399.Arth_2094	0.0	1020.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,1W7WN@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
HKD2_k127_9005205_1	1158050.KB895454_gene1293	1.646e-253	786.0	COG0166@1|root,COG0166@2|Bacteria,2HT2Q@201174|Actinobacteria,1W8PK@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD2_k127_9014639_0	1150398.JIBJ01000001_gene1353	0.0	1626.0	COG0296@1|root,COG3281@1|root,COG0296@2|Bacteria,COG3281@2|Bacteria,2GJ5C@201174|Actinobacteria,1W809@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HKD2_k127_9015930_1	290399.Arth_2789	1.109e-103	342.0	2CAW2@1|root,32RS7@2|Bacteria,2IB15@201174|Actinobacteria,1W9NI@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9015930_0	290399.Arth_2790	2.299e-265	818.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,1W7F8@1268|Micrococcaceae	201174|Actinobacteria	P	CBS domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
HKD2_k127_9022082_2	1151118.KB895790_gene1139	1.512e-123	402.0	COG1414@1|root,COG1414@2|Bacteria,2GJUA@201174|Actinobacteria,1W8QN@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	iclR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
HKD2_k127_9022082_1	930171.Asphe3_30780	1.674e-208	656.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,1W8H1@1268|Micrococcaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
HKD2_k127_9022082_0	290399.Arth_4142	1.18e-261	817.0	COG1620@1|root,COG1620@2|Bacteria,2GIUF@201174|Actinobacteria,1W81F@1268|Micrococcaceae	201174|Actinobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
HKD2_k127_9022082_3	494419.ALPM01000008_gene1871	2.142e-114	374.0	COG2225@1|root,COG2225@2|Bacteria	2|Bacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	GO:0000287,GO:0001968,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009117,GO:0009150,GO:0009259,GO:0009436,GO:0009986,GO:0009987,GO:0015936,GO:0015980,GO:0016020,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0042603,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046810,GO:0046872,GO:0046912,GO:0046983,GO:0048037,GO:0050662,GO:0050840,GO:0051186,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0356	Malate_synthase
HKD2_k127_9026592_5	1349820.M707_03110	1.693e-86	289.0	COG0847@1|root,COG0847@2|Bacteria,2IIG4@201174|Actinobacteria,1W7WS@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T
HKD2_k127_9026592_3	1449044.JMLE01000005_gene576	2.001e-146	467.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,1W96Y@1268|Micrococcaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
HKD2_k127_9026592_4	1449044.JMLE01000005_gene577	2.859e-113	372.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,1W7MW@1268|Micrococcaceae	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HKD2_k127_9026592_2	1077972.ARGLB_096_00400	1.082e-152	484.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,1W7XR@1268|Micrococcaceae	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
HKD2_k127_9026592_1	1150398.JIBJ01000015_gene1980	3.828e-161	526.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,1W84Q@1268|Micrococcaceae	201174|Actinobacteria	S	Beta-lactamase superfamily domain	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HKD2_k127_9026592_0	1150398.JIBJ01000015_gene1981	1.437e-180	569.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,1W8AJ@1268|Micrococcaceae	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HKD2_k127_9029444_1	1101188.KI912156_gene4225	4.535e-140	453.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,1W94P@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	chrS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
HKD2_k127_9029444_0	1150398.JIBJ01000007_gene221	1.015e-141	460.0	COG0577@1|root,COG0577@2|Bacteria,2GMC4@201174|Actinobacteria,1W8KR@1268|Micrococcaceae	201174|Actinobacteria	V	FtsX-like permease family	hrtB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD2_k127_9029444_2	981369.JQMJ01000004_gene1888	1.138e-40	154.0	COG1136@1|root,COG1136@2|Bacteria,2GNB3@201174|Actinobacteria,2NHNM@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	hrtA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_9030376_0	1150398.JIBJ01000002_gene1290	4.025e-173	552.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,1W7X8@1268|Micrococcaceae	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
HKD2_k127_9030376_2	1077972.ARGLB_032_00200	6.577e-59	206.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria,1W9PD@1268|Micrococcaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_9030376_1	1449044.JMLE01000006_gene1033	5.514e-149	478.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,1W7WM@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the amidase family	amiB	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
HKD2_k127_9041264_5	1150398.JIBJ01000005_gene3188	1.024e-58	205.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria,1W7UA@1268|Micrococcaceae	201174|Actinobacteria	S	RarD protein	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
HKD2_k127_9041264_4	1150398.JIBJ01000005_gene3184	2.84e-154	492.0	COG0589@1|root,COG0589@2|Bacteria,2GKQ1@201174|Actinobacteria	201174|Actinobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD2_k127_9041264_3	452863.Achl_2793	6.009e-256	804.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria,1WAFB@1268|Micrococcaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 10	tomA	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
HKD2_k127_9041264_0	452863.Achl_2794	1.944e-320	987.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_9041264_2	452863.Achl_2795	4.841e-259	810.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_9041264_6	68170.KL590512_gene3248	1.761e-46	184.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4EEFB@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
HKD2_k127_9041264_1	1449044.JMLE01000039_gene2024	3.034e-265	818.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,1W8CS@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD2_k127_9054620_2	1101188.KI912155_gene2398	2.861e-181	572.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,1W8HD@1268|Micrococcaceae	201174|Actinobacteria	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HKD2_k127_9054620_1	1158050.KB895456_gene1945	4.712e-259	804.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,1W833@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HKD2_k127_9054620_0	1158050.KB895456_gene1944	7.756e-278	860.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,1W80R@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HKD2_k127_9054620_3	1150398.JIBJ01000006_gene3618	2.176e-66	250.0	COG0295@1|root,COG0295@2|Bacteria,2IHP7@201174|Actinobacteria	201174|Actinobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
HKD2_k127_9054620_4	1150398.JIBJ01000006_gene3617	1.107e-38	153.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,1W8FS@1268|Micrococcaceae	201174|Actinobacteria	F	pyrimidine-nucleoside phosphorylase	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HKD2_k127_9094887_0	1449044.JMLE01000002_gene4300	8.132e-289	891.0	COG0488@1|root,COG0488@2|Bacteria,2I69P@201174|Actinobacteria,1WCBP@1268|Micrococcaceae	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD2_k127_9094887_1	136273.GY22_02365	3.835e-49	184.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,1W8BJ@1268|Micrococcaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
HKD2_k127_9101108_2	1115632.JAFW01000001_gene4347	7.884e-65	235.0	2BFB8@1|root,32949@2|Bacteria,2ISHF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
HKD2_k127_9101108_4	1150398.JIBJ01000008_gene769	2.067e-42	156.0	2DR0Y@1|root,339QH@2|Bacteria,2GWIF@201174|Actinobacteria,1WA8X@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
HKD2_k127_9101108_3	1151119.KB895494_gene3165	1.385e-61	214.0	COG1320@1|root,COG1320@2|Bacteria,2IQXD@201174|Actinobacteria,1W9UU@1268|Micrococcaceae	201174|Actinobacteria	P	TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit	mrpG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
HKD2_k127_9101108_5	1132441.KI519455_gene2948	2.587e-30	123.0	COG2212@1|root,COG2212@2|Bacteria,2GZ4N@201174|Actinobacteria,1WA3N@1268|Micrococcaceae	201174|Actinobacteria	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	mrpF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
HKD2_k127_9101108_1	1150398.JIBJ01000008_gene772	2.405e-93	309.0	COG1863@1|root,COG1863@2|Bacteria,2IQD6@201174|Actinobacteria,1W96R@1268|Micrococcaceae	201174|Actinobacteria	P	Na+/H+ ion antiporter subunit	mrpE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
HKD2_k127_9101108_0	1158050.KB895453_gene750	4.868e-258	800.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria,1W87T@1268|Micrococcaceae	201174|Actinobacteria	CP	Proton-conducting membrane transporter	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
HKD2_k127_9102095_1	1150398.JIBJ01000002_gene953	5.233e-50	178.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,1W939@1268|Micrococcaceae	201174|Actinobacteria	E	Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
HKD2_k127_9102095_0	1150398.JIBJ01000002_gene955	1.673e-187	593.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria	201174|Actinobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
HKD2_k127_9120682_2	930171.Asphe3_11820	9.912e-36	142.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,1W7XW@1268|Micrococcaceae	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD2_k127_9120682_0	290399.Arth_1149	6.174e-117	384.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,1W8MI@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
HKD2_k127_9120682_1	1150398.JIBJ01000006_gene3611	6.678e-71	246.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,1W9DI@1268|Micrococcaceae	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
HKD2_k127_9128997_0	1449044.JMLE01000007_gene1248	3.6e-245	759.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,1W817@1268|Micrococcaceae	201174|Actinobacteria	C	Succinate dehydrogenase flavoprotein subunit	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD2_k127_9128997_2	290340.AAur_1246	1.256e-88	297.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,1W966@1268|Micrococcaceae	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
HKD2_k127_9128997_3	290399.Arth_1131	3.292e-75	254.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,1W9JW@1268|Micrococcaceae	201174|Actinobacteria	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
HKD2_k127_9128997_1	290399.Arth_1132	6.493e-123	399.0	COG0836@1|root,COG0836@2|Bacteria,2GIRM@201174|Actinobacteria,1W7I1@1268|Micrococcaceae	201174|Actinobacteria	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HKD2_k127_9135_1	452863.Achl_0694	2.308e-46	172.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,1W7ZP@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase III, subunits gamma and tau	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD2_k127_9135_0	1449044.JMLE01000025_gene3311	3.58e-125	401.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,1W7NI@1268|Micrococcaceae	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
HKD2_k127_9135_2	1246995.AFR_07375	9.743e-45	164.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4DFCP@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD2_k127_9139999_0	452863.Achl_2052	1.088e-277	863.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,1W8BJ@1268|Micrococcaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
HKD2_k127_9139999_2	1158050.KB895461_gene2932	3.188e-129	422.0	COG2273@1|root,COG2273@2|Bacteria,2IFI2@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
HKD2_k127_9139999_1	1151119.KB895489_gene574	4.786e-141	452.0	COG0121@1|root,COG0121@2|Bacteria,2GJSY@201174|Actinobacteria	201174|Actinobacteria	S	glutamine amidotransferase	-	-	3.5.1.118	ko:K07008	ko00340,map00340	-	R11021	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	GATase_4
HKD2_k127_9139999_3	290399.Arth_1959	1.295e-30	123.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,1WAK6@1268|Micrococcaceae	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_9141973_1	1150398.JIBJ01000002_gene1262	8.808e-134	426.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,1W8S4@1268|Micrococcaceae	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD2_k127_9141973_3	1449044.JMLE01000006_gene1082	1.782e-96	316.0	COG1246@1|root,COG1246@2|Bacteria,2GJBT@201174|Actinobacteria,1W91Z@1268|Micrococcaceae	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	argA	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HKD2_k127_9141973_0	1150398.JIBJ01000002_gene1260	1.9e-199	623.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,1W94S@1268|Micrococcaceae	201174|Actinobacteria	G	Dihydroxyacetone kinase	dhaK	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
HKD2_k127_9141973_2	1150398.JIBJ01000002_gene1259	6.373e-101	340.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,1WAU3@1268|Micrococcaceae	201174|Actinobacteria	S	Dak2	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
HKD2_k127_9141973_4	1150398.JIBJ01000002_gene1258	5.293e-51	186.0	COG1925@1|root,COG3412@1|root,COG1925@2|Bacteria,COG3412@2|Bacteria,2IHRN@201174|Actinobacteria,1WBBT@1268|Micrococcaceae	201174|Actinobacteria	G	PTS system fructose IIA component	dhaM	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man,PTS-HPr
HKD2_k127_9172830_1	1150398.JIBJ01000005_gene3424	3.352e-169	535.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,1W7PD@1268|Micrococcaceae	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HKD2_k127_9172830_3	1150398.JIBJ01000005_gene3423	8.967e-26	119.0	COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,1WA5T@1268|Micrococcaceae	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HKD2_k127_9172830_2	1150398.JIBJ01000005_gene3422	2.017e-157	500.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,1W8TG@1268|Micrococcaceae	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
HKD2_k127_9172830_0	1150398.JIBJ01000005_gene3421	2.717e-268	826.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,1W81C@1268|Micrococcaceae	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_9187131_2	1449044.JMLE01000013_gene2653	4.785e-37	150.0	COG0494@1|root,COG0494@2|Bacteria,2IRKE@201174|Actinobacteria,1W9ZC@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_9187131_1	1150398.JIBJ01000018_gene2202	2.213e-54	201.0	2E4H1@1|root,32ZC5@2|Bacteria,2IFIP@201174|Actinobacteria,1WA2P@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9187131_0	1150398.JIBJ01000018_gene2201	1.278e-103	344.0	COG3371@1|root,COG3371@2|Bacteria,2IP8C@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
HKD2_k127_9188618_5	935839.JAGJ01000010_gene304	1.38e-83	286.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4F57Z@85017|Promicromonosporaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_9188618_1	1045009.AFXQ01000011_gene448	5.599e-137	458.0	COG4177@1|root,COG4177@2|Bacteria,2GNZK@201174|Actinobacteria,1WCHX@1268|Micrococcaceae	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_9188618_2	312284.A20C1_00991	5.207e-135	447.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,3UX74@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_9188618_3	1449058.JQKT01000007_gene1101	1.861e-105	352.0	COG0410@1|root,COG0410@2|Bacteria,2I93D@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
HKD2_k127_9188618_4	1045009.AFXQ01000011_gene445	2.933e-102	340.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,1W9SW@1268|Micrococcaceae	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HKD2_k127_9188618_0	935839.JAGJ01000010_gene309	2.136e-163	523.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4F45N@85017|Promicromonosporaceae	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD2_k127_921829_1	397291.C804_00483	8.614e-05	55.0	2946W@1|root,2ZRMA@2|Bacteria	2|Bacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_921829_0	1210884.HG799462_gene9016	6.577e-05	52.0	COG3415@1|root,COG3415@2|Bacteria,2J3KA@203682|Planctomycetes	203682|Planctomycetes	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_33
HKD2_k127_9219432_0	1077972.ARGLB_111_00450	2.464e-194	618.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,1W7T5@1268|Micrococcaceae	201174|Actinobacteria	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HKD2_k127_9219432_1	1449044.JMLE01000016_gene941	3.272e-47	172.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,1W7X2@1268|Micrococcaceae	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HKD2_k127_9228341_0	1449044.JMLE01000001_gene4152	0.0	1036.0	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria,1W7YU@1268|Micrococcaceae	201174|Actinobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
HKD2_k127_9228341_1	1077972.ARGLB_064_00360	6.228e-144	471.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,1W8M3@1268|Micrococcaceae	201174|Actinobacteria	P	TIGRFAM cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
HKD2_k127_9228341_3	290340.AAur_pTC20043	1.124e-47	172.0	COG0640@1|root,COG0640@2|Bacteria,2IMDE@201174|Actinobacteria,1W9YB@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21885	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
HKD2_k127_9228341_2	1121019.AUMN01000020_gene1621	1.67e-140	449.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,1WAJ3@1268|Micrococcaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
HKD2_k127_9240479_0	1101188.KI912155_gene986	8.198e-123	395.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,1W84I@1268|Micrococcaceae	201174|Actinobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	fprA	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
HKD2_k127_9240479_1	452863.Achl_2792	2.063e-117	384.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria,1W7UA@1268|Micrococcaceae	201174|Actinobacteria	S	RarD protein	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
HKD2_k127_9253010_1	933262.AXAM01000029_gene2747	1.277e-22	100.0	2DNCT@1|root,32WU5@2|Bacteria,1RKZ5@1224|Proteobacteria,42T1G@68525|delta/epsilon subdivisions,2WPD4@28221|Deltaproteobacteria,2MPJX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
HKD2_k127_9253010_0	1121405.dsmv_3391	4.061e-191	606.0	COG0493@1|root,COG2878@1|root,COG0493@2|Bacteria,COG2878@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2WIVF@28221|Deltaproteobacteria,2MIVJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Fe-S cluster domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fer4,Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
HKD2_k127_9260510_2	1449044.JMLE01000014_gene2356	4.337e-65	224.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria,1W9SA@1268|Micrococcaceae	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
HKD2_k127_9260510_0	1150398.JIBJ01000007_gene144	6.909e-204	639.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,1W8IA@1268|Micrococcaceae	201174|Actinobacteria	E	May catalyze the transamination reaction in phenylalanine biosynthesis	pat	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_9260510_1	1150398.JIBJ01000007_gene143	9.166e-120	395.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,1W804@1268|Micrococcaceae	201174|Actinobacteria	C	Pyruvate dehydrogenase	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD2_k127_9260512_0	1150398.JIBJ01000009_gene374	4.154e-229	718.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,1WAP8@1268|Micrococcaceae	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_9260512_1	290399.Arth_1424	1.455e-156	503.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,1W8QE@1268|Micrococcaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
HKD2_k127_9260512_2	290399.Arth_1425	4.512e-60	212.0	2EP16@1|root,33GN1@2|Bacteria,2IR85@201174|Actinobacteria,1W9J0@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_926352_1	1150398.JIBJ01000009_gene384	4.973e-95	312.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,1WAEG@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
HKD2_k127_926352_2	290399.Arth_1433	1.71e-47	171.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,1W9NP@1268|Micrococcaceae	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD2_k127_926352_0	1150398.JIBJ01000009_gene386	0.0	1395.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,1W868@1268|Micrococcaceae	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD2_k127_927437_1	479432.Sros_3614	3.522e-05	46.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4EFZA@85012|Streptosporangiales	201174|Actinobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
HKD2_k127_927437_0	298653.Franean1_6737	9.268e-178	571.0	COG3464@1|root,COG3464@2|Bacteria,2IQ9H@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
HKD2_k127_9274711_0	1158050.KB895461_gene2980	2.728e-141	451.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	yknZ	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
HKD2_k127_9274711_1	1077972.ARGLB_039_00020	3.633e-49	178.0	COG0346@1|root,COG0346@2|Bacteria,2H9P4@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD2_k127_9274740_0	1151119.KB895492_gene1650	4.857e-191	600.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,1W7W9@1268|Micrococcaceae	201174|Actinobacteria	IQ	AMP-binding enzyme	bfmM	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD2_k127_9274740_1	1158050.KB895470_gene2665	7.064e-90	297.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,1W7F3@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_9311181_1	1150398.JIBJ01000014_gene2431	1.525e-133	430.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,1W7PK@1268|Micrococcaceae	201174|Actinobacteria	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD2_k127_9311181_0	1150398.JIBJ01000014_gene2432	1.72e-230	722.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,1W7YT@1268|Micrococcaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD2_k127_9340000_1	1449044.JMLE01000023_gene156	6.747e-217	674.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,1W7H7@1268|Micrococcaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_9340000_0	1150398.JIBJ01000009_gene317	2.019e-223	696.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,1W8HM@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD2_k127_9340000_2	1151118.KB895784_gene3286	1.94e-115	374.0	COG0697@1|root,COG0697@2|Bacteria,2HT24@201174|Actinobacteria,1W8NH@1268|Micrococcaceae	201174|Actinobacteria	EG	Magnesium transporter NIPA	-	-	-	-	-	-	-	-	-	-	-	-	Mg_trans_NIPA
HKD2_k127_9409613_2	1151119.KB895489_gene484	7.344e-42	156.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,1W7PY@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	tcyC	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HKD2_k127_9409613_0	1158050.KB895452_gene619	2.898e-172	546.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,1W8RJ@1268|Micrococcaceae	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	yecS	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HKD2_k127_9409613_1	1158050.KB895452_gene618	4.572e-169	534.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,1W85W@1268|Micrococcaceae	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD2_k127_9450763_3	1150398.JIBJ01000004_gene2640	1.964e-89	295.0	COG1045@1|root,COG1045@2|Bacteria,2IHW5@201174|Actinobacteria,1W7G4@1268|Micrococcaceae	201174|Actinobacteria	E	Serine acetyltransferase	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HKD2_k127_9450763_0	1151119.KB895491_gene1990	1.466e-297	914.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,1W7UK@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
HKD2_k127_9450763_1	1150398.JIBJ01000004_gene2637	5.044e-132	424.0	COG2186@1|root,COG2186@2|Bacteria,2GKBM@201174|Actinobacteria,1W9MP@1268|Micrococcaceae	201174|Actinobacteria	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HKD2_k127_9450763_2	1449044.JMLE01000001_gene3696	1.161e-107	351.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,1W7PF@1268|Micrococcaceae	201174|Actinobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
HKD2_k127_9452246_2	1115632.JAFW01000001_gene4063	3.267e-22	96.0	COG0346@1|root,COG0346@2|Bacteria,2IRQX@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD2_k127_9452246_1	930171.Asphe3_16010	6.254e-81	272.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria,1W9MR@1268|Micrococcaceae	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD2_k127_9452246_0	1150398.JIBJ01000003_gene1906	6.106e-150	477.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,1W7XT@1268|Micrococcaceae	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrA2	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD2_k127_9453677_1	494419.ALPM01000008_gene1870	4.077e-16	78.0	COG3193@1|root,COG3193@2|Bacteria,2IK20@201174|Actinobacteria	201174|Actinobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
HKD2_k127_9453677_0	1158050.KB895452_gene650	1.603e-224	707.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,1W7KT@1268|Micrococcaceae	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
HKD2_k127_9461402_0	290399.Arth_0340	7.632e-193	610.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,1WATE@1268|Micrococcaceae	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
HKD2_k127_9461402_2	1150398.JIBJ01000002_gene1175	5.071e-107	357.0	COG0726@1|root,COG0726@2|Bacteria,2GN6G@201174|Actinobacteria,1WCHE@1268|Micrococcaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HKD2_k127_9461402_1	1150398.JIBJ01000002_gene1174	2.932e-127	413.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,1W82E@1268|Micrococcaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
HKD2_k127_9467260_1	1150398.JIBJ01000018_gene2219	3.93e-145	464.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,1W8HW@1268|Micrococcaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	pimH	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HKD2_k127_9467260_4	1150398.JIBJ01000018_gene2220	2.035e-61	220.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,1WA67@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
HKD2_k127_9467260_3	1449044.JMLE01000013_gene2670	6.264e-74	251.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,1W9DU@1268|Micrococcaceae	201174|Actinobacteria	K	Cold shock protein domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_9467260_0	1150398.JIBJ01000018_gene2223	0.0	1268.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria,1W8YI@1268|Micrococcaceae	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
HKD2_k127_9467260_2	1150398.JIBJ01000018_gene2224	2.461e-78	262.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,1W8GW@1268|Micrococcaceae	201174|Actinobacteria	L	helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
HKD2_k127_9471468_2	1101188.KI912155_gene2407	6.091e-83	278.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,1W828@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HKD2_k127_9471468_1	1150398.JIBJ01000006_gene3613	3.069e-87	298.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,1W97B@1268|Micrococcaceae	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
HKD2_k127_9471468_0	1150398.JIBJ01000006_gene3614	2.193e-135	432.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,1W7MY@1268|Micrococcaceae	201174|Actinobacteria	F	adenosine deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
HKD2_k127_949588_4	1449044.JMLE01000002_gene4436	1.404e-41	154.0	COG0454@1|root,COG0456@2|Bacteria,2I8J8@201174|Actinobacteria,1WA4H@1268|Micrococcaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_949588_1	1150398.JIBJ01000005_gene3280	1.545e-198	623.0	COG3153@1|root,COG3153@2|Bacteria,2IPF8@201174|Actinobacteria,1W8UG@1268|Micrococcaceae	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_949588_2	1150398.JIBJ01000005_gene3281	3.432e-99	326.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,1W8CA@1268|Micrococcaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HKD2_k127_949588_3	452863.Achl_2701	9.456e-64	220.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,1W9KD@1268|Micrococcaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HKD2_k127_949588_0	1150398.JIBJ01000005_gene3283	8.936e-297	922.0	COG0737@1|root,COG0737@2|Bacteria,2GKC3@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.5,3.1.3.6,3.1.4.16	ko:K01081,ko:K01119	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HKD2_k127_9498473_3	290399.Arth_3027	3.745e-82	274.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,1W9AM@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the UPF0336 family	hadA	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
HKD2_k127_9498473_5	1150398.JIBJ01000005_gene3242	1.465e-29	118.0	2B5CS@1|root,31Y6Y@2|Bacteria,2H0B0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3188
HKD2_k127_9498473_2	290399.Arth_3031	5.71e-122	405.0	2C1IE@1|root,32R8R@2|Bacteria,2IJ1X@201174|Actinobacteria,1WAHS@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
HKD2_k127_9498473_0	1158050.KB895452_gene542	5.943e-173	544.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,1W8JD@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HKD2_k127_9498473_1	1150398.JIBJ01000005_gene3239	1.713e-158	505.0	COG4989@1|root,COG4989@2|Bacteria,2GM3C@201174|Actinobacteria,1W8C5@1268|Micrococcaceae	201174|Actinobacteria	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_9498473_4	290399.Arth_3038	8.97e-39	145.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,1W8MG@1268|Micrococcaceae	201174|Actinobacteria	G	PFAM alpha amylase, catalytic	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
HKD2_k127_9521141_0	1449044.JMLE01000006_gene1110	6.944e-209	651.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,1W87Q@1268|Micrococcaceae	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
HKD2_k127_9521141_1	1150398.JIBJ01000002_gene1245	6.442e-158	500.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,1W7YK@1268|Micrococcaceae	201174|Actinobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HKD2_k127_9565187_1	290340.AAur_1214	1.043e-33	131.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,1W8TD@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	araH	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
HKD2_k127_9565187_0	1150398.JIBJ01000006_gene3652	8.578e-310	952.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
HKD2_k127_9565187_2	1150398.JIBJ01000006_gene3651	9.053e-32	124.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,1W806@1268|Micrococcaceae	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
HKD2_k127_9618205_1	1150398.JIBJ01000010_gene596	9.941e-271	839.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GNDC@201174|Actinobacteria,1W7WE@1268|Micrococcaceae	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HKD2_k127_9618205_0	1150398.JIBJ01000010_gene595	5.418e-278	861.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,1W8AB@1268|Micrococcaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HKD2_k127_9620185_2	1150398.JIBJ01000010_gene504	4.023e-55	194.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,1W7UJ@1268|Micrococcaceae	201174|Actinobacteria	L	Deoxyribodipyrimidine photo-lyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
HKD2_k127_9620185_1	290340.AAur_2727	5.011e-142	454.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria,1W7WU@1268|Micrococcaceae	201174|Actinobacteria	KT	Phage shock protein A, PspA	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
HKD2_k127_9620185_0	1150398.JIBJ01000010_gene506	1.827e-320	995.0	COG1512@1|root,COG1512@2|Bacteria,2GMGW@201174|Actinobacteria,1W7FD@1268|Micrococcaceae	201174|Actinobacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HKD2_k127_9620185_3	290340.AAur_2726	0.0007066	46.0	COG1512@1|root,COG4487@1|root,COG1512@2|Bacteria,COG4487@2|Bacteria,2GMGW@201174|Actinobacteria,1W7FD@1268|Micrococcaceae	201174|Actinobacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HKD2_k127_9640220_2	246200.SPO1224	4.112e-14	78.0	COG0433@1|root,COG0433@2|Bacteria,1N28R@1224|Proteobacteria,2U47U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
HKD2_k127_9640220_0	298653.Franean1_3580	2.581e-129	422.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,4ERUS@85013|Frankiales	201174|Actinobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
HKD2_k127_9640220_1	365528.KB891159_gene5407	1.583e-20	94.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2IAHV@201174|Actinobacteria,4EV3F@85013|Frankiales	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_32,HTH_33
HKD2_k127_9650059_0	1122611.KB904012_gene6810	1.604e-171	550.0	COG3385@1|root,COG3385@2|Bacteria,2GJUG@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
HKD2_k127_9650059_1	953739.SVEN_0443	2.238e-07	53.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_9659463_1	1449044.JMLE01000039_gene2026	8.322e-77	258.0	COG3835@1|root,COG3835@2|Bacteria,2IH74@201174|Actinobacteria,1W8PY@1268|Micrococcaceae	201174|Actinobacteria	KT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
HKD2_k127_9659463_0	1449044.JMLE01000039_gene2025	9.391e-298	915.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,1W7W6@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_9659463_2	1077972.ARGLB_080_01330	8.797e-28	113.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,1W8CS@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD2_k127_96728_7	290399.Arth_4015	1.242e-166	526.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,1W7RX@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HKD2_k127_96728_1	1449044.JMLE01000014_gene2373	0.0	1053.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,1W8WV@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD2_k127_96728_6	1150398.JIBJ01000007_gene130	1.01e-175	556.0	COG0673@1|root,COG0673@2|Bacteria,2GN2Z@201174|Actinobacteria,1W9X8@1268|Micrococcaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD2_k127_96728_4	452863.Achl_3803	2.385e-223	701.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,1W7R7@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD2_k127_96728_3	1150398.JIBJ01000007_gene128	2.389e-230	719.0	COG2508@1|root,COG2508@2|Bacteria,2GKV3@201174|Actinobacteria,1W7F2@1268|Micrococcaceae	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
HKD2_k127_96728_9	1150398.JIBJ01000007_gene126	2.134e-62	218.0	COG3311@1|root,COG3311@2|Bacteria,2I5UD@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HKD2_k127_96728_2	1158050.KB895469_gene3168	5.981e-302	932.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,1W8PV@1268|Micrococcaceae	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HKD2_k127_96728_8	1150398.JIBJ01000007_gene124	7.229e-126	406.0	COG1309@1|root,COG1309@2|Bacteria,2I9S3@201174|Actinobacteria,1WB4C@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
HKD2_k127_96728_0	290399.Arth_4004	0.0	1099.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,2GMYR@201174|Actinobacteria,1WAKG@1268|Micrococcaceae	201174|Actinobacteria	G	Phosphotransferase system, EIIC	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HKD2_k127_96728_5	1150398.JIBJ01000007_gene122	8.419e-207	647.0	COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,1W8UE@1268|Micrococcaceae	201174|Actinobacteria	G	Mannitol-1-phosphate 5-dehydrogenase	mtlD	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
HKD2_k127_9674270_1	690850.Desaf_2331	0.000134	44.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,433G7@68525|delta/epsilon subdivisions,2WXN9@28221|Deltaproteobacteria,2MF0Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
HKD2_k127_9674270_0	485913.Krac_2893	2.686e-116	391.0	28JEU@1|root,2Z98W@2|Bacteria	2|Bacteria	S	PFAM MULE transposase, conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	MULE,Transposase_mut
HKD2_k127_9682199_4	1151118.KB895783_gene3701	8.446e-72	253.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,1W98R@1268|Micrococcaceae	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
HKD2_k127_9682199_0	1150398.JIBJ01000005_gene3417	2.806e-194	610.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,1W7U5@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iNJ661.Rv3758c	ABC_tran
HKD2_k127_9682199_2	290399.Arth_2843	2.589e-172	552.0	COG1162@1|root,COG1162@2|Bacteria,2GMDX@201174|Actinobacteria,1WBQ5@1268|Micrococcaceae	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
HKD2_k127_9682199_3	1150398.JIBJ01000005_gene3415	1.033e-78	270.0	COG1051@1|root,COG1051@2|Bacteria,2IQZT@201174|Actinobacteria,1W9MZ@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD2_k127_9682199_1	290399.Arth_2844	2.126e-173	548.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria,1W7EM@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HKD2_k127_9682199_5	1150398.JIBJ01000005_gene3414	4.609e-12	66.0	COG2971@1|root,COG2971@2|Bacteria,2GKNB@201174|Actinobacteria,1W9AX@1268|Micrococcaceae	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD2_k127_9685220_0	1077972.ARGLB_008_01240	3.254e-175	551.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,1W7IU@1268|Micrococcaceae	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
HKD2_k127_9685220_2	1150398.JIBJ01000024_gene3911	1.058e-75	255.0	2CH9A@1|root,33I4V@2|Bacteria,2H5ZY@201174|Actinobacteria,1WBKK@1268|Micrococcaceae	201174|Actinobacteria	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
HKD2_k127_9685220_1	1349820.M707_17765	8.797e-86	286.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,1W8BN@1268|Micrococcaceae	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD2_k127_9687264_0	1380346.JNIH01000004_gene2282	1.514e-121	403.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1
HKD2_k127_9703814_0	290399.Arth_3572	3.576e-234	726.0	COG0025@1|root,COG5207@1|root,COG0025@2|Bacteria,COG5207@2|Bacteria,2GIUT@201174|Actinobacteria,1W86C@1268|Micrococcaceae	201174|Actinobacteria	P	Na H antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
HKD2_k127_9703814_1	452863.Achl_3417	7.737e-118	385.0	COG2085@1|root,COG2085@2|Bacteria,2GJF5@201174|Actinobacteria,1WA22@1268|Micrococcaceae	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
HKD2_k127_9721938_0	1158050.KB895454_gene1349	6.726e-219	679.0	COG0435@1|root,COG0435@2|Bacteria,2GIXK@201174|Actinobacteria,1W8FN@1268|Micrococcaceae	201174|Actinobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
HKD2_k127_9721938_3	1150398.JIBJ01000013_gene2554	2.48e-165	544.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,1W8VN@1268|Micrococcaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD2_k127_9721938_2	1150398.JIBJ01000013_gene2555	4.895e-167	532.0	COG4129@1|root,COG4129@2|Bacteria,2IM22@201174|Actinobacteria,1WA80@1268|Micrococcaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	ArAE_1
HKD2_k127_9721938_4	1150398.JIBJ01000013_gene2556	8.489e-144	481.0	COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,1W92I@1268|Micrococcaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HKD2_k127_9721938_1	1449044.JMLE01000001_gene4036	1.015e-216	677.0	COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria,1W8K3@1268|Micrococcaceae	201174|Actinobacteria	IQ	KR domain	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD2_k127_9739649_2	455632.SGR_4936	9.243e-05	46.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,417TU@629295|Streptomyces griseus group	201174|Actinobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
HKD2_k127_9739649_0	1077972.ARGLB_008_01820	1.14e-125	406.0	COG4221@1|root,COG4221@2|Bacteria,2GJWX@201174|Actinobacteria,1WAII@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_9739649_1	290399.Arth_3409	2.734e-57	203.0	COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,1W9SC@1268|Micrococcaceae	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
HKD2_k127_9743100_3	1150398.JIBJ01000019_gene849	3.114e-137	437.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,1W80S@1268|Micrococcaceae	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
HKD2_k127_9743100_2	1150398.JIBJ01000019_gene850	3.877e-149	482.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD2_k127_9743100_0	1150398.JIBJ01000019_gene851	0.0	1549.0	COG0577@1|root,COG0577@2|Bacteria,2HW2M@201174|Actinobacteria,1WC3Y@1268|Micrococcaceae	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9743100_1	1158050.KB895452_gene74	5.113e-235	728.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,1W8GU@1268|Micrococcaceae	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
HKD2_k127_978399_0	33876.JNXY01000012_gene4247	3.19e-112	366.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4D9RX@85008|Micromonosporales	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HKD2_k127_978399_3	1288083.AUKR01000001_gene1137	1.297e-06	52.0	COG4424@1|root,COG4424@2|Bacteria,2HYF0@201174|Actinobacteria	201174|Actinobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
HKD2_k127_978399_2	106370.Francci3_3263	6.864e-09	63.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
HKD2_k127_978399_1	1121272.KB903291_gene3537	2.96e-32	128.0	COG1661@1|root,COG1661@2|Bacteria,2HWPW@201174|Actinobacteria,4DJVD@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF296
HKD2_k127_978399_5	1121272.KB903291_gene3536	0.000308	49.0	COG1396@1|root,COG1396@2|Bacteria,2IP2C@201174|Actinobacteria	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
HKD2_k127_978399_4	106370.Francci3_2058	5.682e-06	48.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4EWGM@85013|Frankiales	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
HKD2_k127_9806677_2	886293.Sinac_7094	7.967e-75	259.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
HKD2_k127_9806677_0	1454004.AW11_01872	1.738e-125	416.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2VJ2W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
HKD2_k127_9806677_1	76114.ebA1942	1.722e-87	299.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VNSH@28216|Betaproteobacteria,2KYPA@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
HKD2_k127_9806677_3	886293.Sinac_7094	1.621e-35	136.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
HKD2_k127_9824452_0	1150398.JIBJ01000012_gene2073	5e-324	1001.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,1W8BP@1268|Micrococcaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD2_k127_9851202_1	1150398.JIBJ01000002_gene1087	1.19e-162	514.0	COG0171@1|root,COG0171@2|Bacteria,2HFW0@201174|Actinobacteria,1W7S0@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
HKD2_k127_9851202_0	1150398.JIBJ01000002_gene1070	1.998e-201	633.0	COG0654@1|root,COG0654@2|Bacteria,2GXK6@201174|Actinobacteria,1W8JB@1268|Micrococcaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HKD2_k127_9851202_2	290399.Arth_4487	1.04e-107	352.0	COG3544@1|root,COG3544@2|Bacteria,2IKUE@201174|Actinobacteria,1W8KT@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
HKD2_k127_9851202_3	290399.Arth_4485	1.712e-94	314.0	COG4454@1|root,COG4454@2|Bacteria,2I9JP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SoxE
HKD2_k127_9851202_4	290399.Arth_4484	1.189e-39	148.0	COG3462@1|root,COG3462@2|Bacteria,2GWIQ@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
HKD2_k127_9851202_7	1151119.KB895489_gene646	1.373e-30	124.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
HKD2_k127_9851202_6	1101188.KI912155_gene2608	3.962e-35	134.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,1WAPB@1268|Micrococcaceae	201174|Actinobacteria	C	e3 binding domain	-	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_9858845_3	1150398.JIBJ01000004_gene2984	1.316e-36	139.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,1W8F5@1268|Micrococcaceae	201174|Actinobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD2_k127_9858845_0	1150398.JIBJ01000004_gene2983	3.615e-79	274.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria,1W9FG@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
HKD2_k127_9858845_2	290399.Arth_0347	7.168e-64	221.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,1W9UV@1268|Micrococcaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
HKD2_k127_9858845_1	290399.Arth_0348	9.154e-76	267.0	COG0711@1|root,COG0711@2|Bacteria,2IQQZ@201174|Actinobacteria,1WA1F@1268|Micrococcaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9858845_4	1150398.JIBJ01000002_gene1171	1.927e-36	139.0	COG4122@1|root,COG4122@2|Bacteria,2I5RE@201174|Actinobacteria,1WCE5@1268|Micrococcaceae	201174|Actinobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD2_k127_9870289_3	1197706.AKKK01000022_gene2344	5.213e-14	74.0	COG3422@1|root,COG3422@2|Bacteria	2|Bacteria	S	double-strand break repair	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
HKD2_k127_9870289_1	1150398.JIBJ01000024_gene3932	1.526e-129	417.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,1W9CH@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX domain	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HKD2_k127_9870289_0	1150398.JIBJ01000024_gene3933	1.17e-152	489.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,1W7ED@1268|Micrococcaceae	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD2_k127_9870289_2	1449044.JMLE01000004_gene2451	7.395e-38	142.0	2ECJB@1|root,336HD@2|Bacteria,2GMJH@201174|Actinobacteria,1W9P5@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9888038_1	357808.RoseRS_0068	9.015e-33	142.0	COG3385@1|root,COG3385@2|Bacteria,2G8GC@200795|Chloroflexi,376GC@32061|Chloroflexia	32061|Chloroflexia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HKD2_k127_9888038_0	886293.Sinac_5645	9.245e-60	225.0	COG3385@1|root,COG3385@2|Bacteria,2IZKA@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase Tn5 dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_Tn5,Tnp_DNA_bind
HKD2_k127_9910686_1	930171.Asphe3_14980	3.778e-79	267.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,1W7J2@1268|Micrococcaceae	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HKD2_k127_9910686_0	290399.Arth_1516	4.635e-138	442.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,1W8NS@1268|Micrococcaceae	201174|Actinobacteria	J	FtsJ-like methyltransferase	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HKD2_k127_9916181_1	1312959.KI914621_gene2412	3.447e-162	517.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,2GN09@201174|Actinobacteria,1W7MB@1268|Micrococcaceae	201174|Actinobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD2_k127_9916181_0	290399.Arth_1692	1.531e-311	959.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,1W89V@1268|Micrococcaceae	201174|Actinobacteria	E	Glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
HKD2_k127_9916181_2	1132441.KI519454_gene784	1.034e-43	159.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,1W7ZA@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HKD2_k127_9989866_2	1121381.JNIV01000213_gene4188	7.591e-08	57.0	COG3676@1|root,COG3676@2|Bacteria	2|Bacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
HKD2_k127_9989866_0	886293.Sinac_7148	1.119e-245	764.0	COG3385@1|root,COG3385@2|Bacteria,2IZE5@203682|Planctomycetes	203682|Planctomycetes	L	COG5659 FOG Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
HKD2_k127_9989866_1	1210884.HG799465_gene11704	3.284e-31	131.0	COG5659@1|root,COG5659@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
## 2419 queries scanned
## Total time (seconds): 56.59164786338806
## Rate: 42.74 q/s