## Wed Oct 16 20:58:30 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/HKD2_bin.66.fa -m mmseqs --itype genome -o HKD2_bin.66 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/HKD2_bin.66 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD2_k127_10006706_1	1078085.HMPREF1210_02017	6.536e-96	316.0	28K3D@1|root,2Z9SI@2|Bacteria,1UZKH@1239|Firmicutes,4HDH6@91061|Bacilli,26F03@186818|Planococcaceae	91061|Bacilli	S	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS
HKD2_k127_10006706_0	574376.BAMA_20785	7.554e-134	434.0	COG0697@1|root,COG0697@2|Bacteria,1TP9B@1239|Firmicutes,4H9TT@91061|Bacilli,1ZB35@1386|Bacillus	91061|Bacilli	EG	Putative multidrug resistance efflux transporter	yjlA	-	-	-	-	-	-	-	-	-	-	-	EmrE
HKD2_k127_10006706_2	1131730.BAVI_00785	1.429e-93	308.0	COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli,1ZFT9@1386|Bacillus	91061|Bacilli	S	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD2_k127_1002294_16	218284.CCDN010000005_gene3200	9.305e-86	285.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,1ZBIZ@1386|Bacillus	91061|Bacilli	H	Lipoate-protein ligase	lplJ	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
HKD2_k127_1002294_11	1403313.AXBR01000023_gene2397	4.153e-124	401.0	COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,1ZCZE@1386|Bacillus	91061|Bacilli	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HKD2_k127_1002294_23	796606.BMMGA3_04165	9.024e-14	72.0	2C2JF@1|root,33CZ0@2|Bacteria,1VN4G@1239|Firmicutes,4HR1T@91061|Bacilli,1ZK0S@1386|Bacillus	91061|Bacilli	S	YhfH-like protein	yhfH	-	-	-	-	-	-	-	-	-	-	-	YhfH
HKD2_k127_1002294_25	1385514.N782_03495	7.278e-08	55.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1002294_0	1174504.AJTN02000016_gene229	3.41e-263	829.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus	91061|Bacilli	S	YhgE Pip N-terminal domain protein	yhgE	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,DUF3533
HKD2_k127_1002294_15	1403313.AXBR01000023_gene2398	4.068e-91	302.0	COG1309@1|root,COG1309@2|Bacteria,1V2H2@1239|Firmicutes,4HHJD@91061|Bacilli,1ZFYK@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yhgD	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
HKD2_k127_1002294_5	1403313.AXBR01000023_gene2400	1.163e-167	530.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,1ZAZ6@1386|Bacillus	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
HKD2_k127_1002294_3	1403313.AXBR01000023_gene2401	4.668e-199	622.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,4HAXT@91061|Bacilli,1ZDGX@1386|Bacillus	91061|Bacilli	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
HKD2_k127_1002294_19	1403313.AXBR01000023_gene2402	1.994e-67	233.0	COG2329@1|root,COG2329@2|Bacteria,1V501@1239|Firmicutes,4HHA2@91061|Bacilli,1ZGDD@1386|Bacillus	91061|Bacilli	S	enzyme involved in biosynthesis of extracellular polysaccharides	traP	GO:0005575,GO:0016020	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
HKD2_k127_1002294_6	1403313.AXBR01000023_gene2407	7.591e-160	512.0	COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,1ZBQG@1386|Bacillus	91061|Bacilli	U	ABC transporter	ecsB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	EcsB
HKD2_k127_1002294_10	1307436.PBF_03065	4.598e-126	406.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,1ZBAI@1386|Bacillus	91061|Bacilli	V	transporter (ATP-binding protein)	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_1002294_18	1403313.AXBR01000023_gene2409	2.239e-78	263.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,1ZGI0@1386|Bacillus	91061|Bacilli	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HKD2_k127_1002294_2	1403313.AXBR01000023_gene2410	8.996e-200	625.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,1ZB9N@1386|Bacillus	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD2_k127_1002294_20	1403313.AXBR01000023_gene2412	5.323e-35	137.0	COG4980@1|root,COG4980@2|Bacteria,1VAKP@1239|Firmicutes,4HKD5@91061|Bacilli,1ZJ3D@1386|Bacillus	91061|Bacilli	S	YtxH-like protein	yhaH	-	-	-	-	-	-	-	-	-	-	-	YtxH
HKD2_k127_1002294_14	1403313.AXBR01000023_gene2413	2.066e-100	329.0	COG1846@1|root,COG1846@2|Bacteria,1UY04@1239|Firmicutes,4HBQS@91061|Bacilli,1ZBRK@1386|Bacillus	91061|Bacilli	K	Negative regulator of protease production and sporulation	hpr	GO:0000003,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K09682	-	-	-	-	ko00000,ko03000	-	-	-	MarR
HKD2_k127_1002294_22	665952.HMPREF1015_01665	2.721e-19	91.0	2C7NP@1|root,32YAN@2|Bacteria,1VF0A@1239|Firmicutes,4HPFX@91061|Bacilli,1ZJ09@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1002294_12	1403313.AXBR01000023_gene2415	1.224e-113	373.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus	91061|Bacilli	M	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K01802,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,Trigger_C
HKD2_k127_1002294_17	265729.GS18_0204495	7.473e-81	276.0	COG2138@1|root,COG2138@2|Bacteria,1TRDV@1239|Firmicutes,4H9RT@91061|Bacilli,1ZGH1@1386|Bacillus	91061|Bacilli	S	Sirohydrochlorin ferrochelatase	sirB	-	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
HKD2_k127_1002294_7	265729.GS18_0204490	8.499e-137	437.0	COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,1ZBV1@1386|Bacillus	91061|Bacilli	H	Belongs to the precorrin methyltransferase family	cobA	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15610	TP_methylase
HKD2_k127_1002294_13	265729.GS18_0204485	1.577e-108	353.0	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,1ZBCZ@1386|Bacillus	91061|Bacilli	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
HKD2_k127_1002294_1	265729.GS18_0204480	1.313e-205	644.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,1ZCB4@1386|Bacillus	91061|Bacilli	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
HKD2_k127_1002294_8	265729.GS18_0204470	4.878e-132	422.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,1ZCBJ@1386|Bacillus	91061|Bacilli	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15570	PAPS_reduct
HKD2_k127_1002294_4	1347368.HG964407_gene6769	2.273e-186	586.0	COG1118@1|root,COG1118@2|Bacteria,1UI6I@1239|Firmicutes,4ISFJ@91061|Bacilli,1ZS5E@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
HKD2_k127_1002294_9	1347368.HG964407_gene6770	3.241e-126	409.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,4H9XE@91061|Bacilli,1ZB4T@1386|Bacillus	91061|Bacilli	P	COG4208 ABC-type sulfate transport system, permease component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
HKD2_k127_10043581_6	1198452.Jab_2c02210	1.587e-07	55.0	COG1879@1|root,COG1879@2|Bacteria,1MXQN@1224|Proteobacteria,2VS1W@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Periplasmic binding protein LacI transcriptional regulator	torT	-	-	ko:K11930	-	-	-	-	ko00000	-	-	-	Peripla_BP_1,Peripla_BP_4
HKD2_k127_10043581_0	748727.CLJU_c01270	1.956e-103	355.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	iHN637.CLJU_RS00620	ABC_tran
HKD2_k127_10043581_3	675812.VHA_002366	1.145e-69	248.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XZQJ@135623|Vibrionales	135623|Vibrionales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HKD2_k127_10043581_1	1343739.PAP_05465	4.001e-80	275.0	COG1540@1|root,arCOG05810@2157|Archaea,2XVRI@28890|Euryarchaeota,242SZ@183968|Thermococci	183968|Thermococci	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
HKD2_k127_10043581_5	1235835.C814_00930	2.371e-48	182.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia,3WNN6@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:AHS1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
HKD2_k127_10043581_2	649747.HMPREF0083_00419	6.131e-70	249.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HTJN@91061|Bacilli,2725A@186822|Paenibacillaceae	91061|Bacilli	E	Pfam:AHS2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
HKD2_k127_10043581_4	926561.KB900617_gene1388	5.247e-62	226.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WAG1@53433|Halanaerobiales	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD2_k127_1007868_13	265729.GS18_0213460	2.331e-38	145.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,1ZDBB@1386|Bacillus	91061|Bacilli	E	belongs to the PRA-CH family	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
HKD2_k127_1007868_12	1034347.CAHJ01000027_gene3893	4.104e-50	180.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,1ZDBB@1386|Bacillus	91061|Bacilli	E	belongs to the PRA-CH family	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
HKD2_k127_1007868_2	1403313.AXBR01000013_gene1324	1.135e-148	471.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,1ZAUX@1386|Bacillus	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14115	His_biosynth
HKD2_k127_1007868_5	1403313.AXBR01000013_gene1323	8.3e-132	424.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,1ZC7D@1386|Bacillus	91061|Bacilli	E	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD2_k127_1007868_8	1403313.AXBR01000013_gene1322	1.747e-107	350.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,1ZBC4@1386|Bacillus	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD2_k127_1007868_7	1174504.AJTN02000230_gene1225	7.148e-111	360.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,1ZBVJ@1386|Bacillus	91061|Bacilli	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14130	IGPD
HKD2_k127_1007868_0	1403313.AXBR01000013_gene1320	3.861e-209	656.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus	91061|Bacilli	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU34910	Histidinol_dh
HKD2_k127_1007868_6	1174504.AJTN02000230_gene1223	3.807e-119	384.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,1ZCFW@1386|Bacillus	91061|Bacilli	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,tRNA-synt_His
HKD2_k127_1007868_1	1403313.AXBR01000013_gene1318	8.279e-204	639.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,1ZB4H@1386|Bacillus	91061|Bacilli	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
HKD2_k127_1007868_10	1405.DJ92_2219	9.535e-84	280.0	COG0110@1|root,COG0110@2|Bacteria,1V1SM@1239|Firmicutes,4HFTP@91061|Bacilli,1ZBJ5@1386|Bacillus	91061|Bacilli	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	yvoF	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
HKD2_k127_1007868_9	1307436.PBF_08553	7.487e-86	289.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4HE7X@91061|Bacilli,1ZB95@1386|Bacillus	91061|Bacilli	S	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool	ppaX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD2_k127_1007868_3	1403313.AXBR01000013_gene1312	1.042e-139	451.0	COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,4HAIZ@91061|Bacilli,1ZAYP@1386|Bacillus	91061|Bacilli	P	COG0370 Fe2 transport system protein B	yvoD	-	-	-	-	-	-	-	-	-	-	-	Gate
HKD2_k127_1007868_4	1403313.AXBR01000013_gene1311	2.902e-136	437.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,1ZAR8@1386|Bacillus	91061|Bacilli	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HKD2_k127_1007868_11	1403313.AXBR01000013_gene1310	1.095e-82	276.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,1ZD05@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HKD2_k127_10108778_3	871963.Desdi_1621	6.651e-54	193.0	COG1064@1|root,COG1064@2|Bacteria	2|Bacteria	P	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_10108778_4	1120972.AUMH01000002_gene2667	3.482e-16	78.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4HB69@91061|Bacilli,279AQ@186823|Alicyclobacillaceae	91061|Bacilli	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD2_k127_10108778_0	398511.BpOF4_02075	1.55e-142	463.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4HB69@91061|Bacilli,1ZQUT@1386|Bacillus	91061|Bacilli	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD2_k127_10108778_1	1120973.AQXL01000132_gene2247	5.301e-94	316.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,2794N@186823|Alicyclobacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD2_k127_10108778_2	1120973.AQXL01000132_gene2248	8.04e-60	208.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,279C1@186823|Alicyclobacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD2_k127_10126803_2	1403313.AXBR01000006_gene48	1.075e-187	591.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD2_k127_10126803_0	1403313.AXBR01000006_gene50	1.86e-209	659.0	COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus	91061|Bacilli	V	Multidrug efflux pump	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HKD2_k127_10126803_4	1403313.AXBR01000006_gene52	1.247e-42	160.0	2DR1M@1|root,339SJ@2|Bacteria,1VMD6@1239|Firmicutes,4HRV5@91061|Bacilli,1ZGEB@1386|Bacillus	91061|Bacilli	S	COG0071 Molecular chaperone (small heat shock protein)	yozR	-	-	-	-	-	-	-	-	-	-	-	CS
HKD2_k127_10126803_5	1403313.AXBR01000006_gene54	8.378e-40	151.0	2E327@1|root,32Y2F@2|Bacteria,1VEQD@1239|Firmicutes,4HPXZ@91061|Bacilli,1ZQS0@1386|Bacillus	91061|Bacilli	S	YtkA-like	ytkA	-	-	-	-	-	-	-	-	-	-	-	YtkA
HKD2_k127_10126803_1	1403313.AXBR01000006_gene55	1.426e-208	658.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HANF@91061|Bacilli,1ZS27@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_10126803_3	1403313.AXBR01000006_gene56	2.544e-93	310.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZARN@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_10139322_8	1403313.AXBR01000002_gene4434	1.811e-11	66.0	COG5444@1|root,COG5444@2|Bacteria,1UZ44@1239|Firmicutes,4HDSN@91061|Bacilli,1ZB37@1386|Bacillus	91061|Bacilli	S	LXG domain of WXG superfamily	-	-	-	-	-	-	-	-	-	-	-	-	LXG,Ntox15,PT-TG
HKD2_k127_10139322_10	873449.STRCR_0253	1.166e-07	54.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,DUF11,HemolysinCabind,PT-VENN
HKD2_k127_10139322_4	315749.Bcer98_0196	1.69e-135	435.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,1ZC55@1386|Bacillus	91061|Bacilli	S	reductase	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_10139322_9	857293.CAAU_0268	9.497e-09	59.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,36DNH@31979|Clostridiaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD2_k127_10139322_0	1033734.CAET01000060_gene2025	8.717e-189	591.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli,1ZB8Z@1386|Bacillus	91061|Bacilli	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_10139322_6	1403313.AXBR01000023_gene2697	4.569e-14	72.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,1ZM61@1386|Bacillus	91061|Bacilli	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD2_k127_10139322_3	1211814.CAPG01000078_gene3719	7.444e-140	449.0	COG1024@1|root,COG1024@2|Bacteria,1UZG3@1239|Firmicutes,4HDQ0@91061|Bacilli,1ZD6Y@1386|Bacillus	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD2_k127_10139322_7	1340434.AXVA01000016_gene701	1.318e-13	72.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_10139322_5	1243664.CAVL020000037_gene947	1.704e-110	364.0	COG1302@1|root,COG1302@2|Bacteria,1V1TU@1239|Firmicutes,4HG8E@91061|Bacilli,1ZFEB@1386|Bacillus	91061|Bacilli	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_10139322_2	666686.B1NLA3E_10920	7.931e-141	459.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,1ZC54@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	cda1	GO:0005575,GO:0016020	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CBM_6,DUF3298,DUF4163,Polysacc_deac_1
HKD2_k127_10139322_1	1403313.AXBR01000022_gene2819	1.697e-183	580.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,1ZB1N@1386|Bacillus	91061|Bacilli	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	yqiG	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HKD2_k127_10188490_0	796606.BMMGA3_10495	2.102e-222	708.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	gmr	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9
HKD2_k127_10188490_1	1403313.AXBR01000007_gene292	3.386e-216	674.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus	91061|Bacilli	L	Belongs to the methyltransferase superfamily	ypsC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
HKD2_k127_10190896_0	796606.BMMGA3_15230	2.363e-271	846.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,4HEM3@91061|Bacilli,1ZDPH@1386|Bacillus	91061|Bacilli	KT	HD domain	M1-580	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_3,PAS_9
HKD2_k127_10190896_1	1340434.AXVA01000007_gene5002	4.722e-07	51.0	29T3W@1|root,30EAG@2|Bacteria,1UCBE@1239|Firmicutes,4INTU@91061|Bacilli,1ZNXZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_10190896_2	1340434.AXVA01000007_gene5002	3.682e-06	48.0	29T3W@1|root,30EAG@2|Bacteria,1UCBE@1239|Firmicutes,4INTU@91061|Bacilli,1ZNXZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_10197447_18	1227360.C176_06877	1.479e-63	218.0	COG0491@1|root,COG0491@2|Bacteria,1UZGY@1239|Firmicutes,4HBDD@91061|Bacilli,26DY8@186818|Planococcaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_10197447_28	935836.JAEL01000018_gene1085	9.243e-16	79.0	29RXV@1|root,30D25@2|Bacteria,1UAQH@1239|Firmicutes,4IM35@91061|Bacilli,1ZIZ9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_10197447_27	981383.AEWH01000071_gene1098	3.239e-16	83.0	2DU7D@1|root,33P82@2|Bacteria,1VMSY@1239|Firmicutes,4HSFM@91061|Bacilli	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2187
HKD2_k127_10197447_9	1403313.AXBR01000014_gene2228	4.7e-134	430.0	COG1506@1|root,COG1506@2|Bacteria,1U5SB@1239|Firmicutes,4HB1A@91061|Bacilli,1ZC9W@1386|Bacillus	91061|Bacilli	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	ytmA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HKD2_k127_10197447_25	1403313.AXBR01000014_gene2229	1.135e-32	128.0	2EA0D@1|root,3345V@2|Bacteria,1VES6@1239|Firmicutes,4HNHV@91061|Bacilli,1ZHVU@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2584)	ytmB	-	-	-	-	-	-	-	-	-	-	-	DUF2584
HKD2_k127_10197447_21	1033734.CAET01000058_gene1911	1.063e-46	171.0	COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,4HKWP@91061|Bacilli,1ZH86@1386|Bacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_10197447_10	1444309.JAQG01000171_gene397	1.106e-115	376.0	COG3860@1|root,COG3860@2|Bacteria,1TPHH@1239|Firmicutes,4HCHE@91061|Bacilli,26TD0@186822|Paenibacillaceae	91061|Bacilli	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GerE
HKD2_k127_10197447_22	1132442.KB889752_gene3632	1.662e-42	159.0	COG3860@1|root,COG3860@2|Bacteria,1VH55@1239|Firmicutes,4IQ7W@91061|Bacilli,1ZRHX@1386|Bacillus	91061|Bacilli	S	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
HKD2_k127_10197447_0	1211814.CAPG01000080_gene3764	2.656e-288	891.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus	91061|Bacilli	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09060,iYO844.BSU30560	PEPCK_ATP
HKD2_k127_10197447_24	935836.JAEL01000097_gene3436	5.352e-40	151.0	COG3011@1|root,COG3011@2|Bacteria,1VJ6C@1239|Firmicutes,4HP2J@91061|Bacilli,1ZGQM@1386|Bacillus	91061|Bacilli	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
HKD2_k127_10197447_2	1403313.AXBR01000014_gene2240	9.587e-230	716.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,1ZBHR@1386|Bacillus	91061|Bacilli	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD2_k127_10197447_13	1403313.AXBR01000014_gene2241	9.743e-97	318.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4HFPC@91061|Bacilli,1ZBFS@1386|Bacillus	91061|Bacilli	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	ytoA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD2_k127_10197447_7	1403313.AXBR01000014_gene2242	1.199e-150	479.0	COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,1ZBD1@1386|Bacillus	91061|Bacilli	I	Alpha beta hydrolase	ytpA	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
HKD2_k127_10197447_20	1234664.AMRO01000077_gene3272	9.515e-53	189.0	COG3193@1|root,COG3193@2|Bacteria,1V5C7@1239|Firmicutes,4HHN9@91061|Bacilli,1WGSJ@129337|Geobacillus	91061|Bacilli	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
HKD2_k127_10197447_6	1234664.AMRO01000077_gene3271	2.286e-167	529.0	COG0346@1|root,COG0346@2|Bacteria,1TRBJ@1239|Firmicutes,4HADI@91061|Bacilli,1WFNK@129337|Geobacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HKD2_k127_10197447_26	1234664.AMRO01000077_gene3263	1.053e-30	122.0	COG1018@1|root,COG1018@2|Bacteria,1VKC9@1239|Firmicutes,4HRAY@91061|Bacilli,1WHKB@129337|Geobacillus	91061|Bacilli	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	Fer2
HKD2_k127_10197447_4	1234664.AMRO01000077_gene3262	5.426e-175	568.0	COG1719@1|root,COG2508@1|root,COG1719@2|Bacteria,COG2508@2|Bacteria,1TRK4@1239|Firmicutes,4HB2R@91061|Bacilli	91061|Bacilli	T	hydrocarbon binding protein (contains V4R domain)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,V4R,XylR_N
HKD2_k127_10197447_1	649747.HMPREF0083_02462	7.842e-284	877.0	COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,4HG6M@91061|Bacilli,271UI@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
HKD2_k127_10197447_23	1211814.CAPG01000019_gene636	8.002e-42	156.0	2DMJY@1|root,32UH5@2|Bacteria,1VB6N@1239|Firmicutes,4HM39@91061|Bacilli,1ZHPA@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_10197447_11	649747.HMPREF0083_02460	1.101e-101	344.0	COG2207@1|root,COG2207@2|Bacteria,1V5UU@1239|Firmicutes,4HFX2@91061|Bacilli	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC
HKD2_k127_10197447_14	935837.JAEK01000034_gene3054	1.21e-96	320.0	COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,4HDC3@91061|Bacilli,1ZR9J@1386|Bacillus	91061|Bacilli	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
HKD2_k127_10197447_12	649747.HMPREF0083_02460	1.711e-97	332.0	COG2207@1|root,COG2207@2|Bacteria,1V5UU@1239|Firmicutes,4HFX2@91061|Bacilli	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC
HKD2_k127_10197447_15	1403313.AXBR01000014_gene2244	3.076e-88	294.0	COG0275@1|root,COG0275@2|Bacteria,1UHPG@1239|Firmicutes,4IS5B@91061|Bacilli,1ZFKV@1386|Bacillus	91061|Bacilli	M	Putative rRNA methylase	ytqB	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
HKD2_k127_10197447_3	1403313.AXBR01000014_gene2245	4.89e-197	615.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli,1ZBM1@1386|Bacillus	91061|Bacilli	S	Fe-S oxidoreductase	ytqA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
HKD2_k127_10197447_19	1211035.CD30_00105	1.811e-56	200.0	COG1846@1|root,COG1846@2|Bacteria,1VBQ1@1239|Firmicutes,4HMXC@91061|Bacilli,3IXZY@400634|Lysinibacillus	91061|Bacilli	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HKD2_k127_10197447_5	345219.Bcoa_0775	1.752e-169	540.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_10197447_17	935837.JAEK01000002_gene1974	2.665e-74	255.0	COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,1ZDP2@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ycfA	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_10197447_8	1131730.BAVI_25175	2.389e-147	474.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,1ZAPY@1386|Bacillus	91061|Bacilli	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD2_k127_10197447_16	935837.JAEK01000002_gene1972	3.886e-86	287.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,1ZDAX@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	ybhF_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_10200503_3	1139996.OMQ_01943	4.403e-27	116.0	2CKMR@1|root,32VKF@2|Bacteria,1VAAV@1239|Firmicutes,4HKU6@91061|Bacilli,4B3B9@81852|Enterococcaceae	91061|Bacilli	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
HKD2_k127_10200503_1	1403313.AXBR01000023_gene2500	4.786e-144	464.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBXS@1386|Bacillus	91061|Bacilli	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	yrpB	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
HKD2_k127_10200503_2	218284.CCDN010000001_gene686	4.62e-88	294.0	COG1268@1|root,COG1268@2|Bacteria,1TS7R@1239|Firmicutes,4HC1H@91061|Bacilli,1ZCIP@1386|Bacillus	91061|Bacilli	S	Biotin biosynthesis protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HKD2_k127_10200503_0	997296.PB1_11139	4.958e-172	544.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,4HAGM@91061|Bacilli,1ZCAU@1386|Bacillus	91061|Bacilli	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30200	BATS,Radical_SAM
HKD2_k127_1064468_7	1267580.AF6_0293	1.587e-07	55.0	COG1918@1|root,COG1918@2|Bacteria,1VK8Z@1239|Firmicutes,4HR83@91061|Bacilli,21X5G@150247|Anoxybacillus	91061|Bacilli	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HKD2_k127_1064468_3	1403313.AXBR01000012_gene1207	3.939e-113	367.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus	91061|Bacilli	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_1064468_2	1403313.AXBR01000012_gene1208	3.799e-126	406.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,1ZCXP@1386|Bacillus	91061|Bacilli	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_1064468_1	1403313.AXBR01000012_gene1213	1.919e-129	417.0	COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus	91061|Bacilli	IQ	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD2_k127_1064468_4	1403313.AXBR01000005_gene1890	3.934e-58	205.0	COG3238@1|root,COG3238@2|Bacteria,1V6JD@1239|Firmicutes,4IR7J@91061|Bacilli,1ZRS6@1386|Bacillus	91061|Bacilli	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
HKD2_k127_1064468_5	665952.HMPREF1015_01246	4.627e-55	197.0	COG2172@1|root,COG2172@2|Bacteria,1V6Y4@1239|Firmicutes,4HIQU@91061|Bacilli,1ZG7T@1386|Bacillus	91061|Bacilli	T	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
HKD2_k127_1064468_0	666686.B1NLA3E_02750	7.019e-311	962.0	COG1366@1|root,COG3852@1|root,COG1366@2|Bacteria,COG3852@2|Bacteria,1TT64@1239|Firmicutes,4HCAK@91061|Bacilli,1ZDJS@1386|Bacillus	91061|Bacilli	T	STAS domain	rsbRD	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	HATPase_c,HisKA,STAS
HKD2_k127_1064468_6	1449063.JMLS01000003_gene1849	3.044e-36	144.0	COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,26V0I@186822|Paenibacillaceae	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K06595	-	-	-	-	ko00000,ko02035	-	-	-	MCPsignal,Protoglobin
HKD2_k127_1089065_0	997296.PB1_09392	1.514e-161	512.0	2BZ6P@1|root,2Z8AB@2|Bacteria,1TRT3@1239|Firmicutes,4HD7G@91061|Bacilli,1ZQQP@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF2935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2935
HKD2_k127_1089065_2	1131730.BAVI_16907	2.103e-61	214.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,1ZH0E@1386|Bacillus	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
HKD2_k127_1089065_1	1340434.AXVA01000020_gene1422	7.076e-98	325.0	COG1651@1|root,COG1651@2|Bacteria,1V6IC@1239|Firmicutes,4HIBC@91061|Bacilli,1ZR7I@1386|Bacillus	91061|Bacilli	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HKD2_k127_1089065_3	1157490.EL26_12220	2.101e-52	191.0	COG1668@1|root,COG1668@2|Bacteria,1V5UX@1239|Firmicutes,4HJFQ@91061|Bacilli	91061|Bacilli	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HKD2_k127_1134631_4	1033738.CAEP01000060_gene2620	9.939e-39	149.0	COG1414@1|root,COG1414@2|Bacteria,1TQS2@1239|Firmicutes,4HFQN@91061|Bacilli,26EX0@186818|Planococcaceae	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_1134631_3	246194.CHY_1736	1.226e-74	259.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42EVN@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149,5.3.3.18	ko:K07546,ko:K08299,ko:K15866	ko00360,ko00623,ko01100,ko01120,ko01220,map00360,map00623,map01100,map01120,map01220	M00418	R05599,R09837,R09839,R10675	RC00004,RC00326,RC01095,RC01435,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD2_k127_1134631_2	1231057.AMGD01000006_gene2657	1.372e-179	567.0	COG1960@1|root,COG1960@2|Bacteria,1UUIF@1239|Firmicutes,4HDSX@91061|Bacilli,26EN9@186818|Planococcaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
HKD2_k127_1134631_1	1231057.AMGD01000006_gene2656	1.831e-224	698.0	COG1960@1|root,COG1960@2|Bacteria,1UZSE@1239|Firmicutes,4H9NI@91061|Bacilli,26E0T@186818|Planococcaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_1134631_0	1132442.KB889753_gene120	0.0	1352.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD2_k127_115913_2	192952.MM_3222	1.001e-33	133.0	arCOG04910@1|root,arCOG04910@2157|Archaea	2157|Archaea	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
HKD2_k127_115913_1	192952.MM_1221	3.552e-44	162.0	arCOG04743@1|root,arCOG04743@2157|Archaea,2XXSX@28890|Euryarchaeota,2NA4F@224756|Methanomicrobia	224756|Methanomicrobia	S	Non-histone chromosomal protein MC1	-	-	-	-	-	-	-	-	-	-	-	-	MC1
HKD2_k127_115913_0	192952.MM_0680	7.457e-100	327.0	COG1432@1|root,arCOG02408@2157|Archaea,2XX7V@28890|Euryarchaeota,2N9P5@224756|Methanomicrobia	224756|Methanomicrobia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
HKD2_k127_1169865_4	1385513.N780_01305	2.064e-06	51.0	COG0671@1|root,COG0671@2|Bacteria,1UYGU@1239|Firmicutes,4HB7A@91061|Bacilli,2Y98J@289201|Pontibacillus	91061|Bacilli	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD2_k127_1169865_2	666686.B1NLA3E_05480	1.207e-71	244.0	COG0454@1|root,COG0456@2|Bacteria,1V47B@1239|Firmicutes,4HHAS@91061|Bacilli,1ZI27@1386|Bacillus	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_1169865_1	1294265.JCM21738_5331	1.755e-93	309.0	COG0492@1|root,COG0492@2|Bacteria,1UXYT@1239|Firmicutes,4HDB8@91061|Bacilli,1ZBEB@1386|Bacillus	91061|Bacilli	O	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
HKD2_k127_1169865_3	649639.Bcell_1171	1.448e-42	163.0	29SJQ@1|root,30DQY@2|Bacteria,1UBK1@1239|Firmicutes,4IMZZ@91061|Bacilli,1ZMCG@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1169865_0	1403313.AXBR01000022_gene2792	9.552e-192	601.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus	91061|Bacilli	E	COG2309 Leucyl aminopeptidase (aminopeptidase T)	ampS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
HKD2_k127_1183839_5	265729.GS18_0213850	1.164e-10	64.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4IQSP@91061|Bacilli,1ZRN9@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD2_k127_1183839_1	406124.ACPC01000020_gene3904	5.46e-145	469.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,1ZBZB@1386|Bacillus	91061|Bacilli	M	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
HKD2_k127_1183839_3	406124.ACPC01000020_gene3905	1.08e-100	333.0	COG0463@1|root,COG0463@2|Bacteria,1TSFF@1239|Firmicutes,4HCPR@91061|Bacilli,1ZS5R@1386|Bacillus	91061|Bacilli	M	Glycosyltransferase like family 2	tuaG	-	-	ko:K16698	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD2_k127_1183839_0	406124.ACPC01000020_gene3908	7.178e-177	564.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD2_k127_1183839_2	406124.ACPC01000020_gene3909	1.009e-132	428.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD2_k127_1183839_4	406124.ACPC01000020_gene3912	5.466e-50	182.0	COG1216@1|root,COG1216@2|Bacteria,1VDZ5@1239|Firmicutes,4IPQ8@91061|Bacilli,1ZHYW@1386|Bacillus	91061|Bacilli	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_1285023_0	913865.DOT_1392	8.154e-87	316.0	COG0745@1|root,COG3852@1|root,COG4191@1|root,COG0745@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1UKQJ@1239|Firmicutes,25GUU@186801|Clostridia,267HU@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HKD2_k127_1287370_0	1117379.BABA_21031	4.495e-182	573.0	COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,1ZB12@1386|Bacillus	91061|Bacilli	E	amino acid	lysP	-	-	ko:K11733	-	-	-	-	ko00000,ko02000	2.A.3.1.2	-	-	AA_permease
HKD2_k127_1287370_1	1117379.BABA_21026	1.161e-127	413.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZDFA@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yitT3	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD2_k127_1287370_2	1499680.CCFE01000030_gene3456	3.551e-87	294.0	COG4990@1|root,COG4990@2|Bacteria,1UYFQ@1239|Firmicutes,4HJET@91061|Bacilli,1ZRG6@1386|Bacillus	91061|Bacilli	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HKD2_k127_1287370_4	218284.CCDN010000002_gene2057	5.072e-14	72.0	COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus	91061|Bacilli	S	general stress protein	ydaG	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyrid_ox_like
HKD2_k127_1287370_3	1231057.AMGD01000081_gene887	6.601e-25	104.0	COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,26FDN@186818|Planococcaceae	91061|Bacilli	S	general stress protein	ydaG	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyrid_ox_like
HKD2_k127_1306186_1	1134413.ANNK01000017_gene1870	2.01e-75	259.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,1ZCM7@1386|Bacillus	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD2_k127_1306186_5	1117379.BABA_22793	1.365e-47	178.0	COG2199@1|root,COG2199@2|Bacteria,1VATI@1239|Firmicutes,4HIV8@91061|Bacilli,1ZI6H@1386|Bacillus	91061|Bacilli	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HKD2_k127_1306186_0	218284.CCDN010000001_gene1484	6.004e-91	301.0	COG1978@1|root,COG1978@2|Bacteria,1V6RQ@1239|Firmicutes,4HG45@91061|Bacilli,1ZG17@1386|Bacillus	91061|Bacilli	S	Ribonuclease H-like	-	-	-	ko:K09776	-	-	-	-	ko00000	-	-	-	RNaseH_like
HKD2_k127_1306186_6	1384057.CD33_06630	0.0006968	44.0	28N5J@1|root,2ZBAR@2|Bacteria,1V0YS@1239|Firmicutes,4HYNX@91061|Bacilli	91061|Bacilli	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1306186_4	1196028.ALEF01000016_gene2685	6.336e-54	194.0	COG1406@1|root,COG1406@2|Bacteria,1V9SN@1239|Firmicutes,4HJCY@91061|Bacilli	91061|Bacilli	N	inhibitor of MCP methylation, homolog of CheC	cheX	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
HKD2_k127_1306186_3	935836.JAEL01000002_gene553	9.767e-59	205.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,4HGY2@91061|Bacilli,1ZG7Q@1386|Bacillus	91061|Bacilli	T	response regulator	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
HKD2_k127_1306186_2	1236973.JCM9157_4356	1.303e-71	249.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
HKD2_k127_1315760_2	1347086.CCBA010000005_gene4119	7.464e-19	85.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,4HA6G@91061|Bacilli,1ZD7J@1386|Bacillus	91061|Bacilli	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD2_k127_1315760_1	1231057.AMGD01000028_gene1949	1.129e-58	211.0	COG2755@1|root,COG2755@2|Bacteria,1VAXZ@1239|Firmicutes,4HMD9@91061|Bacilli	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_1315760_0	1305836.AXVE01000002_gene3153	4.308e-74	258.0	COG0840@1|root,COG1366@1|root,COG0840@2|Bacteria,COG1366@2|Bacteria,1UYVT@1239|Firmicutes,4HDB6@91061|Bacilli,26DH3@186818|Planococcaceae	91061|Bacilli	NT	transmembrane signaling receptor activity	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	STAS
HKD2_k127_1319233_5	1403313.AXBR01000021_gene3064	1.002e-205	641.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus	91061|Bacilli	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD2_k127_1319233_13	1403313.AXBR01000021_gene3063	6.566e-83	277.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,1ZG6S@1386|Bacillus	91061|Bacilli	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HKD2_k127_1319233_2	1174504.AJTN02000199_gene4611	1.239e-210	657.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus	91061|Bacilli	K	Participates in both transcription termination and antitermination	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HKD2_k127_1319233_18	1403313.AXBR01000021_gene3060	2.228e-42	156.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,1ZHSV@1386|Bacillus	91061|Bacilli	K	nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
HKD2_k127_1319233_16	1174504.AJTN02000199_gene4613	2.299e-46	168.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,1ZI1N@1386|Bacillus	91061|Bacilli	J	ribosomal protein	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
HKD2_k127_1319233_0	1403313.AXBR01000021_gene3058	0.0	1194.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HKD2_k127_1319233_17	1403313.AXBR01000021_gene3057	1.124e-45	166.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,4HNXC@91061|Bacilli,1ZI43@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
HKD2_k127_1319233_14	1403313.AXBR01000021_gene3056	1.922e-63	218.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,1ZGB3@1386|Bacillus	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD2_k127_1319233_7	1174504.AJTN02000199_gene4617	8.586e-158	501.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
HKD2_k127_1319233_10	1403313.AXBR01000021_gene3054	1.464e-150	481.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,1ZBFH@1386|Bacillus	91061|Bacilli	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06310	FAD_syn,Flavokinase
HKD2_k127_1319233_15	265729.GS18_0205025	8.315e-47	169.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,1ZH7M@1386|Bacillus	91061|Bacilli	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD2_k127_1319233_1	1461580.CCAS010000004_gene537	0.0	1176.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD2_k127_1319233_21	1385514.N782_03495	9.106e-05	46.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1319233_9	1403313.AXBR01000021_gene3051	6.051e-153	488.0	COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,4HAHC@91061|Bacilli,1ZC6V@1386|Bacillus	91061|Bacilli	G	Sporulation protein, polysaccharide deacetylase	ylxY	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_1319233_4	1403313.AXBR01000021_gene3050	1.312e-209	657.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli,1ZDJE@1386|Bacillus	91061|Bacilli	S	Belongs to the peptidase M16 family	mlpA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD2_k127_1319233_19	1403313.AXBR01000021_gene3049	3.704e-34	134.0	COG1873@1|root,COG1873@2|Bacteria,1VEJW@1239|Firmicutes,4HPFQ@91061|Bacilli,1ZI6Z@1386|Bacillus	91061|Bacilli	S	YlmC YmxH family	ymxH	-	-	-	-	-	-	-	-	-	-	-	PRC
HKD2_k127_1319233_8	1403313.AXBR01000021_gene3048	1.406e-157	500.0	COG1052@1|root,COG1052@2|Bacteria,1UI1W@1239|Firmicutes,4HA71@91061|Bacilli,1ZAZJ@1386|Bacillus	91061|Bacilli	CH	Dipicolinate synthase subunit A	dpaA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K06410	-	-	-	-	ko00000	-	-	iYO844.BSU16730	2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N
HKD2_k127_1319233_12	1403313.AXBR01000021_gene3047	2.303e-112	364.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,4HAU9@91061|Bacilli,1ZCJQ@1386|Bacillus	91061|Bacilli	H	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	iYO844.BSU16740	Flavoprotein
HKD2_k127_1319233_20	1294265.JCM21738_1787	1.434e-05	48.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD2_k127_1319233_6	1403313.AXBR01000021_gene3046	2.454e-189	596.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,1ZAVS@1386|Bacillus	91061|Bacilli	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD2_k127_1319233_3	1403313.AXBR01000021_gene3045	2.975e-210	659.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZBSQ@1386|Bacillus	91061|Bacilli	E	Belongs to the aspartokinase family	dapG	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
HKD2_k127_1319233_11	1403313.AXBR01000021_gene3044	7.293e-150	477.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD2_k127_1367964_1	1111479.AXAR01000005_gene632	1.873e-74	253.0	COG3832@1|root,COG3832@2|Bacteria,1VPKT@1239|Firmicutes,4IIMY@91061|Bacilli,27AN4@186823|Alicyclobacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD2_k127_1367964_0	765913.ThidrDRAFT_4634	1.217e-95	327.0	COG0160@1|root,COG0160@2|Bacteria,1QY1E@1224|Proteobacteria,1T4FT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.33	ko:K20428	ko00525,ko01130,map00525,map01130	-	R02773	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
HKD2_k127_1367964_2	666686.B1NLA3E_09705	4.335e-63	224.0	28V78@1|root,2ZHAD@2|Bacteria,1W2H7@1239|Firmicutes,4I0PG@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1385822_5	1347369.CCAD010000062_gene4039	2.257e-34	135.0	2B68X@1|root,31Z68@2|Bacteria,1V93N@1239|Firmicutes,4HIJ8@91061|Bacilli,1ZFXK@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1385822_1	1131730.BAVI_11719	5.348e-133	430.0	COG1131@1|root,COG1131@2|Bacteria,1TQD5@1239|Firmicutes,4HBW8@91061|Bacilli,1ZCFU@1386|Bacillus	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_1385822_4	1211814.CAPG01000014_gene494	3.294e-48	175.0	COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,4HKVW@91061|Bacilli,1ZH42@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
HKD2_k127_1385822_2	1403313.AXBR01000007_gene452	4.305e-116	378.0	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,1ZBRZ@1386|Bacillus	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HKD2_k127_1385822_0	1403313.AXBR01000007_gene453	2.243e-142	457.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqjP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_1385822_3	1403313.AXBR01000007_gene454	1.674e-98	327.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD2_k127_139179_1	1403313.AXBR01000006_gene29	0.0	1014.0	COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus	91061|Bacilli	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	odhA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HKD2_k127_139179_8	1403313.AXBR01000006_gene30	6.883e-95	318.0	COG3384@1|root,COG3384@2|Bacteria,1TSRZ@1239|Firmicutes,4HAAN@91061|Bacilli,1ZBC3@1386|Bacillus	91061|Bacilli	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
HKD2_k127_139179_11	1403313.AXBR01000006_gene31	6.733e-82	280.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HEQR@91061|Bacilli,1ZEGM@1386|Bacillus	91061|Bacilli	G	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_139179_0	1403313.AXBR01000006_gene32	0.0	1939.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus	91061|Bacilli	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HKD2_k127_139179_2	491915.Aflv_2165	5.651e-264	826.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,21VE8@150247|Anoxybacillus	91061|Bacilli	E	Methylenetetrahydrofolate reductase	yitJ	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
HKD2_k127_139179_3	997296.PB1_13084	8.421e-200	636.0	COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus	91061|Bacilli	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.1.3.21,1.1.5.3	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	-	R00846,R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HKD2_k127_139179_6	1403313.AXBR01000006_gene36	1.538e-138	448.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli,1ZB9J@1386|Bacillus	91061|Bacilli	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
HKD2_k127_139179_5	1403313.AXBR01000006_gene37	1.22e-139	453.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus	91061|Bacilli	L	ATP-dependent DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_M
HKD2_k127_139179_7	1403313.AXBR01000006_gene37	9.443e-107	349.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus	91061|Bacilli	L	ATP-dependent DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_M
HKD2_k127_139179_4	1403313.AXBR01000006_gene38	4.741e-156	497.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,1ZD98@1386|Bacillus	91061|Bacilli	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD2_k127_139179_9	1403313.AXBR01000006_gene40	3.511e-87	291.0	COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,4HFQA@91061|Bacilli,1ZB5T@1386|Bacillus	91061|Bacilli	P	Reversible hydration of carbon dioxide	ytiB	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD2_k127_139179_10	1403313.AXBR01000006_gene41	1.547e-83	284.0	2AN4K@1|root,31D2C@2|Bacteria,1U9HP@1239|Firmicutes,4IJMR@91061|Bacilli,1ZBF7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_139179_13	1403313.AXBR01000006_gene43	2.492e-42	158.0	COG3296@1|root,COG3296@2|Bacteria,1VJNI@1239|Firmicutes,4HKFS@91061|Bacilli,1ZQSE@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
HKD2_k127_139179_12	1403313.AXBR01000006_gene45	9.161e-82	275.0	COG1670@1|root,COG1670@2|Bacteria,1V0BB@1239|Firmicutes,4HAK2@91061|Bacilli,1ZDJN@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD2_k127_139179_14	1385514.N782_03495	0.0008562	43.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1405667_1	665959.HMPREF1013_03913	2.902e-22	97.0	COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,4HA3D@91061|Bacilli,1ZAUE@1386|Bacillus	91061|Bacilli	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD2_k127_1405667_0	1131730.BAVI_03254	2.936e-243	753.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus	91061|Bacilli	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_1405667_2	1230342.CTM_16166	7.425e-09	61.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,36DVY@31979|Clostridiaceae	1239|Firmicutes	EG	Spore germination protein	-	-	-	ko:K06295,ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
HKD2_k127_14146_2	1038866.KB902821_gene7487	2.477e-16	81.0	COG4122@1|root,COG4122@2|Bacteria,1P7RY@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD2_k127_14146_0	997296.PB1_00350	6.27e-186	584.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4HB2M@91061|Bacilli,1ZE0N@1386|Bacillus	91061|Bacilli	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HKD2_k127_14146_1	997296.PB1_00345	2.873e-18	85.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4ITCR@91061|Bacilli	91061|Bacilli	M	GDP-mannose 4,6 dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HKD2_k127_1428967_0	661478.OP10G_0619	1.742e-66	244.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
HKD2_k127_1428967_1	886293.Sinac_7569	2.798e-53	207.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
HKD2_k127_1428967_2	714943.Mucpa_3893	9.822e-14	81.0	COG1807@1|root,COG1807@2|Bacteria,4NXH6@976|Bacteroidetes,1IVBY@117747|Sphingobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1451135_5	1169144.KB910935_gene2009	1.327e-90	303.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHIC@91061|Bacilli,1ZC3A@1386|Bacillus	91061|Bacilli	KT	LuxR family transcriptional regulator	yfiK	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
HKD2_k127_1451135_3	1174504.AJTN02000185_gene136	1.399e-111	374.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HHFU@91061|Bacilli,1ZPX5@1386|Bacillus	91061|Bacilli	T	Histidine kinase	baeS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
HKD2_k127_1451135_1	1403313.AXBR01000002_gene4373	9.04e-228	711.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,1ZBR5@1386|Bacillus	91061|Bacilli	E	Belongs to the aspartokinase family	lysC	GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU03790	AA_kinase,ACT,ACT_7
HKD2_k127_1451135_4	265729.GS18_0202895	8.997e-103	335.0	COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli,1ZB8C@1386|Bacillus	91061|Bacilli	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
HKD2_k127_1451135_2	1131730.BAVI_10116	9.209e-120	392.0	COG1622@1|root,COG1622@2|Bacteria,1TPF6@1239|Firmicutes,4HA9J@91061|Bacilli,1ZB28@1386|Bacillus	91061|Bacilli	C	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I	qoxA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600	1.10.3.12	ko:K02826	ko00190,ko01100,map00190,map01100	M00416	R09492	RC00819	ko00000,ko00001,ko00002,ko01000	3.D.4.1	-	iSB619.SA_RS05175	COX2,COX2_TM
HKD2_k127_1451135_0	1403313.AXBR01000002_gene4380	8.423e-314	969.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus	91061|Bacilli	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	qoxB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.10.3.12	ko:K02827	ko00190,ko01100,map00190,map01100	M00416	R09492	RC00819	ko00000,ko00001,ko00002,ko01000	3.D.4.1	-	-	COX1
HKD2_k127_1470784_1	1340434.AXVA01000003_gene2458	2.864e-158	509.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20951	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	PQQ_2
HKD2_k127_1470784_2	509191.AEDB02000075_gene2813	1.288e-18	99.0	2DTQ8@1|root,33M9P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1470784_0	666686.B1NLA3E_02805	0.0	2275.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,4HBZV@91061|Bacilli,1ZIHT@1386|Bacillus	91061|Bacilli	G	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
HKD2_k127_147613_3	1174504.AJTN02000211_gene3638	2.743e-22	99.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03697,ko:K04086	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,UVR
HKD2_k127_147613_1	235909.GK1038	1.23e-85	288.0	COG3291@1|root,COG3291@2|Bacteria,1V0FC@1239|Firmicutes,4HES3@91061|Bacilli,1WE6R@129337|Geobacillus	91061|Bacilli	S	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
HKD2_k127_147613_0	1382358.JHVN01000010_gene1558	4.413e-148	475.0	COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli	91061|Bacilli	L	uV damage repair endonuclease	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
HKD2_k127_147613_2	1405.DJ92_3407	4.667e-27	113.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,1ZQCE@1386|Bacillus	91061|Bacilli	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD2_k127_1478982_7	1131730.BAVI_23423	4e-79	267.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,1ZEV1@1386|Bacillus	91061|Bacilli	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
HKD2_k127_1478982_3	1131730.BAVI_23428	7.07e-109	366.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,4HIDJ@91061|Bacilli,1ZR3V@1386|Bacillus	91061|Bacilli	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX,DHHW
HKD2_k127_1478982_0	1403313.AXBR01000008_gene666	5.285e-238	741.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,1ZBCW@1386|Bacillus	91061|Bacilli	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD2_k127_1478982_8	1403313.AXBR01000008_gene665	1.138e-77	260.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,4HHCF@91061|Bacilli,1ZFKT@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	cymR	GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044212,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:1901363	-	ko:K17472	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
HKD2_k127_1478982_2	1403313.AXBR01000008_gene664	7.362e-206	645.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus	91061|Bacilli	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD2_k127_1478982_1	1403313.AXBR01000008_gene663	4.994e-232	720.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD2_k127_1478982_9	666686.B1NLA3E_11445	2.232e-66	231.0	COG0346@1|root,COG0346@2|Bacteria,1V6MB@1239|Firmicutes,4IR8V@91061|Bacilli,1ZRSM@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD2_k127_1478982_6	1122921.KB898186_gene4829	5.136e-87	293.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,26S2B@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_1478982_4	666686.B1NLA3E_17600	5.974e-102	332.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4HEIB@91061|Bacilli,1ZEZ9@1386|Bacillus	91061|Bacilli	L	COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
HKD2_k127_1478982_12	265729.GS18_0215980	2.756e-10	63.0	29S5Q@1|root,30DA8@2|Bacteria,1UB2B@1239|Firmicutes,4IMF7@91061|Bacilli,1ZK0P@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1478982_11	1273538.G159_09935	4.754e-18	88.0	2DR0X@1|root,339QF@2|Bacteria,1VKZP@1239|Firmicutes,4HRD3@91061|Bacilli,26GC8@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1478982_10	1078085.HMPREF1210_01001	7.297e-55	195.0	2E3QE@1|root,32YNC@2|Bacteria,1VGUX@1239|Firmicutes,4HNTQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1478982_14	883114.HMPREF9709_00153	0.0003683	45.0	2E3AZ@1|root,32YAF@2|Bacteria,1VF37@1239|Firmicutes,24R3T@186801|Clostridia,22HTH@1570339|Peptoniphilaceae	186801|Clostridia	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
HKD2_k127_1478982_5	1403313.AXBR01000008_gene662	1.866e-91	302.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
HKD2_k127_1493805_3	1403313.AXBR01000005_gene1845	1.534e-190	603.0	COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,1ZASU@1386|Bacillus	91061|Bacilli	E	Belongs to the serine threonine dehydratase family. DsdA subfamily	dsdA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008721,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	PALP
HKD2_k127_1493805_2	1403313.AXBR01000005_gene1846	3.928e-230	725.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HBKC@91061|Bacilli,1ZDNI@1386|Bacillus	91061|Bacilli	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
HKD2_k127_1493805_4	1403313.AXBR01000005_gene1847	5.799e-154	492.0	COG2141@1|root,COG2141@2|Bacteria,1TQWJ@1239|Firmicutes,4HBMR@91061|Bacilli,1ZAPR@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	yvbT	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_1493805_0	1117379.BABA_19891	1.275e-318	990.0	COG1112@1|root,COG1112@2|Bacteria,1UNF1@1239|Firmicutes,4IPKF@91061|Bacilli,1ZDR8@1386|Bacillus	91061|Bacilli	L	COG1112 Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
HKD2_k127_1493805_1	1403313.AXBR01000005_gene1851	1.601e-314	970.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZC6I@1386|Bacillus	91061|Bacilli	E	oligoendopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD2_k127_1493805_6	1385514.N782_03495	1.208e-05	48.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1493805_5	1396.DJ87_2923	6.558e-102	334.0	COG1182@1|root,COG1182@2|Bacteria,1UGCK@1239|Firmicutes,4HAPQ@91061|Bacilli,1ZR58@1386|Bacillus	91061|Bacilli	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
HKD2_k127_149861_0	1403313.AXBR01000007_gene278	6.911e-237	745.0	COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus	91061|Bacilli	S	Dynamin family	ypbR	GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529	-	-	-	-	-	-	-	-	-	-	Dynamin_N
HKD2_k127_149861_3	1403313.AXBR01000007_gene280	3.745e-68	236.0	COG1755@1|root,COG1755@2|Bacteria,1V6IY@1239|Firmicutes,4HIFN@91061|Bacilli,1ZGT0@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ypbQ	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
HKD2_k127_149861_2	1403313.AXBR01000007_gene281	8.134e-177	560.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus	91061|Bacilli	Q	Naringenin-chalcone synthase	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
HKD2_k127_149861_4	491915.Aflv_1362	2.241e-52	188.0	COG1406@1|root,COG1406@2|Bacteria,1V9SN@1239|Firmicutes,4HJCY@91061|Bacilli,21VUU@150247|Anoxybacillus	91061|Bacilli	N	Chemotaxis phosphatase CheX	cheX	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
HKD2_k127_149861_5	1117379.BABA_02447	1.333e-08	56.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,1ZCU1@1386|Bacillus	91061|Bacilli	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	HNH,RVT_1
HKD2_k127_149861_1	1384057.CD33_14910	8.887e-194	617.0	COG2199@1|root,COG2199@2|Bacteria,1TR65@1239|Firmicutes,4HBA6@91061|Bacilli,3IVYA@400634|Lysinibacillus	91061|Bacilli	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
HKD2_k127_1525806_0	1403313.AXBR01000021_gene3232	5.769e-129	414.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZCBT@1386|Bacillus	91061|Bacilli	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22640	PALP
HKD2_k127_1525806_2	1403313.AXBR01000021_gene3231	8.71e-114	372.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,1ZC5U@1386|Bacillus	91061|Bacilli	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HKD2_k127_1525806_3	1243664.CAVL020000025_gene1609	1.029e-85	288.0	COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,1ZCEH@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0637 family	yktB	-	-	-	-	-	-	-	-	-	-	-	DUF1054
HKD2_k127_1525806_1	1403313.AXBR01000021_gene3227	7.404e-118	385.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,1ZAS1@1386|Bacillus	91061|Bacilli	G	Inositol monophosphatase	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HKD2_k127_1525806_5	1403313.AXBR01000021_gene3226	2.533e-19	89.0	2DPF7@1|root,331TZ@2|Bacteria,1VEDX@1239|Firmicutes,4HPQF@91061|Bacilli,1ZK0B@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5325
HKD2_k127_1525806_6	1034347.CAHJ01000011_gene2229	3.071e-10	61.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,1ZB9R@1386|Bacillus	91061|Bacilli	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
HKD2_k127_1543417_4	1117379.BABA_14762	2.437e-17	82.0	2AMYB@1|root,31CVE@2|Bacteria,1W36W@1239|Firmicutes,4I0UP@91061|Bacilli,1ZPS3@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1543417_0	1403313.AXBR01000005_gene1842	9.933e-211	663.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB2U@91061|Bacilli,1ZB5R@1386|Bacillus	91061|Bacilli	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	gabR	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
HKD2_k127_1543417_1	981383.AEWH01000050_gene95	2.481e-170	539.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli	91061|Bacilli	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
HKD2_k127_1543417_2	1403313.AXBR01000005_gene1840	1.038e-72	250.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,1ZD5C@1386|Bacillus	91061|Bacilli	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
HKD2_k127_1543417_3	1403313.AXBR01000005_gene1837	2.028e-70	242.0	COG0431@1|root,COG0431@2|Bacteria,1V7R9@1239|Firmicutes,4HJFY@91061|Bacilli,1ZH1J@1386|Bacillus	91061|Bacilli	S	FMN reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
HKD2_k127_156945_0	1347086.CCBA010000031_gene971	4.668e-145	466.0	COG3544@1|root,COG3544@2|Bacteria,1UZIE@1239|Firmicutes,4HD94@91061|Bacilli,1ZDCC@1386|Bacillus	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD2_k127_156945_1	1461580.CCAS010000013_gene1711	8.25e-41	158.0	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4HCGU@91061|Bacilli,1ZFSM@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	yocH	-	-	-	-	-	-	-	-	-	-	-	3D,LysM
HKD2_k127_161796_0	1274524.BSONL12_18394	7.972e-136	449.0	COG5444@1|root,COG5444@2|Bacteria,1UZ44@1239|Firmicutes,4HDSN@91061|Bacilli,1ZB37@1386|Bacillus	91061|Bacilli	S	LXG domain of WXG superfamily	-	-	-	-	-	-	-	-	-	-	-	-	LXG,Ntox15,PT-TG
HKD2_k127_161796_3	1124780.ANNU01000078_gene760	1.126e-24	109.0	COG1714@1|root,COG1714@2|Bacteria,4NW7J@976|Bacteroidetes,47X24@768503|Cytophagia	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD2_k127_161796_4	1121091.AUMP01000006_gene4144	4.725e-22	98.0	2ENUM@1|root,33GFQ@2|Bacteria,1VKUV@1239|Firmicutes,4HR78@91061|Bacilli	91061|Bacilli	S	Family of unknown function (DUF5344)	ywqI	-	-	-	-	-	-	-	-	-	-	-	DUF5344
HKD2_k127_161796_5	279010.BL03861	1.62e-20	95.0	2E38D@1|root,30E31@2|Bacteria,1UC2A@1239|Firmicutes,4INID@91061|Bacilli,1ZNIQ@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF5082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5082
HKD2_k127_161796_2	665959.HMPREF1013_05268	8.728e-26	112.0	2CK53@1|root,33EWP@2|Bacteria,1VNC3@1239|Firmicutes,4HSK6@91061|Bacilli,1ZC8G@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5383)	yueC	-	-	-	-	-	-	-	-	-	-	-	DUF5383
HKD2_k127_161796_1	1196031.ALEG01000042_gene2324	2.243e-125	411.0	COG1511@1|root,COG1511@2|Bacteria,1UZD1@1239|Firmicutes,4HEK8@91061|Bacilli,1ZC64@1386|Bacillus	91061|Bacilli	S	domain protein	yueB	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
HKD2_k127_1668791_3	634956.Geoth_1126	1.078e-15	87.0	2A26D@1|root,30QGZ@2|Bacteria,1V5Z0@1239|Firmicutes,4HHP3@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1668791_1	1462526.BN990_04489	1.12e-19	89.0	2DSPR@1|root,33GZ3@2|Bacteria,1VPAK@1239|Firmicutes,4HRQJ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1668791_5	562743.JH976441_gene400	7.843e-12	67.0	2ESK9@1|root,33K4V@2|Bacteria,1VKCF@1239|Firmicutes,4HSU5@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1668791_2	1462526.BN990_04492	1.973e-16	80.0	2EIPK@1|root,33CF0@2|Bacteria,1VQ5D@1239|Firmicutes,4HS46@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1668791_4	1462526.BN990_04495	8.664e-13	69.0	2DSBF@1|root,33FDM@2|Bacteria,1VKAB@1239|Firmicutes,4HST0@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1668791_0	634956.Geoth_1120	5.865e-26	110.0	2EGYB@1|root,33AQF@2|Bacteria,1VPC3@1239|Firmicutes,4HRVC@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1677345_5	1403313.AXBR01000024_gene4800	6.171e-19	87.0	2EPEG@1|root,33H12@2|Bacteria,1VK9A@1239|Firmicutes,4HSBT@91061|Bacilli,1ZK9G@1386|Bacillus	91061|Bacilli	S	IDEAL	-	-	-	-	-	-	-	-	-	-	-	-	IDEAL
HKD2_k127_1677345_2	1307436.PBF_05168	4.418e-66	230.0	29323@1|root,2ZQJA@2|Bacteria,1UMPM@1239|Firmicutes,4ITY4@91061|Bacilli,1ZD3A@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1677345_1	935837.JAEK01000019_gene762	1.001e-66	230.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,4HJH0@91061|Bacilli,1ZGEW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF523)	ybbK	-	-	-	-	-	-	-	-	-	-	-	DUF523
HKD2_k127_1677345_6	935837.JAEK01000017_gene1348	2.296e-09	62.0	2EPRW@1|root,328T4@2|Bacteria,1UURW@1239|Firmicutes,4I6SK@91061|Bacilli,1ZK92@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1677345_0	665952.HMPREF1015_02156	1.217e-139	449.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1657,DUF421
HKD2_k127_1677345_4	665952.HMPREF1015_02157	3.737e-28	114.0	2EPX8@1|root,33HHR@2|Bacteria,1VG9Y@1239|Firmicutes,4HPWQ@91061|Bacilli,1ZISM@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1657)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1657
HKD2_k127_1677345_3	1382358.JHVN01000005_gene3054	2.917e-33	128.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,4H9W9@91061|Bacilli,21VKB@150247|Anoxybacillus	91061|Bacilli	I	Stage V sporulation protein AD (SpoVAD)	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
HKD2_k127_1694817_5	1403313.AXBR01000028_gene5081	3.112e-51	182.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,1ZGZ0@1386|Bacillus	91061|Bacilli	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HKD2_k127_1694817_3	1403313.AXBR01000028_gene5080	1.144e-93	309.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,1ZFIJ@1386|Bacillus	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD2_k127_1694817_6	1174504.AJTN02000193_gene4153	2.572e-42	155.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,1ZHUE@1386|Bacillus	91061|Bacilli	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HKD2_k127_1694817_2	1403313.AXBR01000028_gene5078	1.924e-97	328.0	COG4241@1|root,COG4241@2|Bacteria,1UZYE@1239|Firmicutes,4HAFH@91061|Bacilli,1ZC1B@1386|Bacillus	91061|Bacilli	S	membrane	yybS	-	-	-	-	-	-	-	-	-	-	-	DUF2232
HKD2_k127_1694817_0	1403313.AXBR01000028_gene5077	0.0	1090.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus	91061|Bacilli	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
HKD2_k127_1694817_4	1403313.AXBR01000028_gene5076	1.668e-76	258.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,1ZGEE@1386|Bacillus	91061|Bacilli	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HKD2_k127_1694817_1	1403313.AXBR01000028_gene5075	5.273e-118	381.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD2_k127_169514_3	562743.JH976434_gene1171	4.399e-06	49.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli	91061|Bacilli	G	Phosphoglucomutase	pgcA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD2_k127_169514_2	1340434.AXVA01000001_gene1174	1.715e-37	145.0	29RAQ@1|root,30CCF@2|Bacteria,1U9MH@1239|Firmicutes,4IJSY@91061|Bacilli,1ZG4U@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5365)	yhcU	-	-	-	-	-	-	-	-	-	-	-	DUF5365
HKD2_k127_169514_0	1340434.AXVA01000001_gene1173	1.579e-118	388.0	COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,1ZDMG@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD2_k127_169514_1	796606.BMMGA3_03760	8.317e-39	145.0	COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,1ZJBG@1386|Bacillus	91061|Bacilli	S	membrane	ydaS	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
HKD2_k127_1749274_6	1294265.JCM21738_873	9.989e-08	53.0	COG1887@1|root,COG1887@2|Bacteria,1TP75@1239|Firmicutes,4H9Q1@91061|Bacilli,1ZB61@1386|Bacillus	91061|Bacilli	M	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	tagB	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_1,Glyphos_transf
HKD2_k127_1749274_1	1033734.CAET01000067_gene2131	1.152e-140	454.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HVYS@91061|Bacilli,1ZS2C@1386|Bacillus	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_1749274_5	1131730.BAVI_17062	6.105e-38	145.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HNJ5@91061|Bacilli,1ZI1Q@1386|Bacillus	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K19449	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD2_k127_1749274_0	666686.B1NLA3E_04410	1.567e-189	598.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HBZ8@91061|Bacilli,1ZCTS@1386|Bacillus	91061|Bacilli	E	Belongs to the DegT DnrJ EryC1 family	epsN	-	-	ko:K19430	-	-	-	-	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
HKD2_k127_1749274_3	666686.B1NLA3E_04405	2.237e-74	255.0	COG0110@1|root,COG0110@2|Bacteria,1V8CV@1239|Firmicutes,4HJ0P@91061|Bacilli,1ZGBH@1386|Bacillus	91061|Bacilli	GM	COG0110 Acetyltransferase (isoleucine patch superfamily)	epsM	GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
HKD2_k127_1749274_2	666686.B1NLA3E_04400	6.332e-88	293.0	COG2148@1|root,COG2148@2|Bacteria,1TP49@1239|Firmicutes,4HFZV@91061|Bacilli,1ZC89@1386|Bacillus	91061|Bacilli	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	epsL	GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0016740,GO:0016772,GO:0016780,GO:0043170,GO:0044238,GO:0071704	-	ko:K13012,ko:K19428	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
HKD2_k127_1749274_4	1196031.ALEG01000067_gene4782	1.944e-45	166.0	COG0438@1|root,COG0438@2|Bacteria,1V09V@1239|Firmicutes,4HM8X@91061|Bacilli,1ZAUY@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD2_k127_1752218_5	1347369.CCAD010000048_gene200	9.993e-65	226.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus	91061|Bacilli	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD2_k127_1752218_8	1348908.KI518615_gene1208	8.464e-09	58.0	2DGYU@1|root,2ZXTP@2|Bacteria,1W5PW@1239|Firmicutes,4I0AQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1752218_3	1340434.AXVA01000003_gene2539	7.446e-78	265.0	COG2258@1|root,COG2258@2|Bacteria,1UB2C@1239|Firmicutes,4HB26@91061|Bacilli,1ZCRA@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yflK	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
HKD2_k127_1752218_1	796606.BMMGA3_09800	5.787e-148	480.0	COG3852@1|root,COG3852@2|Bacteria,1TSQA@1239|Firmicutes,4HD59@91061|Bacilli,1ZDM3@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
HKD2_k127_1752218_6	1340434.AXVA01000016_gene724	1.798e-31	126.0	2E4AM@1|root,32XKC@2|Bacteria,1VE9E@1239|Firmicutes,4HN07@91061|Bacilli,1ZJ0J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1752218_7	1117379.BABA_18797	1.071e-30	121.0	2CGYI@1|root,32YUY@2|Bacteria,1VGI2@1239|Firmicutes,4HPBN@91061|Bacilli,1ZJ06@1386|Bacillus	91061|Bacilli	S	Cold-inducible protein YdjO	-	-	-	-	-	-	-	-	-	-	-	-	YdjO
HKD2_k127_1752218_2	1236973.JCM9157_4196	7.873e-105	348.0	COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4HD3P@91061|Bacilli,1ZDCB@1386|Bacillus	91061|Bacilli	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD2_k127_1752218_0	1117379.BABA_18807	3.101e-159	507.0	COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,1ZD4R@1386|Bacillus	91061|Bacilli	F	nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
HKD2_k127_1752218_4	666686.B1NLA3E_11910	3.376e-70	243.0	COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus	91061|Bacilli	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.1.3.21,1.1.5.3	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	-	R00846,R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HKD2_k127_1760786_1	1461580.CCAS010000024_gene2463	3.884e-70	244.0	28XAZ@1|root,2ZJ8Y@2|Bacteria,1V2XT@1239|Firmicutes,4HGD4@91061|Bacilli,1ZG66@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1760786_2	1461580.CCAS010000024_gene2464	9.28e-64	226.0	29UJD@1|root,30FWM@2|Bacteria,1V548@1239|Firmicutes,4HIC6@91061|Bacilli,1ZGAZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1760786_4	1499680.CCFE01000021_gene2190	9.051e-36	138.0	29RY1@1|root,30D2B@2|Bacteria,1UAQR@1239|Firmicutes,4IM3C@91061|Bacilli,1ZJ0C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1760786_0	1262449.CP6013_2154	1.679e-121	417.0	COG1404@1|root,COG1404@2|Bacteria,1TS1X@1239|Firmicutes,24B4P@186801|Clostridia,36HUH@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S8 family	-	-	-	ko:K20486	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S8
HKD2_k127_1760786_3	309799.DICTH_0238	1.244e-36	160.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
HKD2_k127_1788938_0	1405.DJ92_4474	8.187e-251	781.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus	91061|Bacilli	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	yvdB	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HKD2_k127_1788938_1	1118054.CAGW01000119_gene3392	2.516e-161	514.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes	1239|Firmicutes	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
HKD2_k127_1788938_4	1169144.KB910935_gene2006	1.206e-99	337.0	COG0842@1|root,COG0842@2|Bacteria,1V7HN@1239|Firmicutes,4HGE5@91061|Bacilli,1ZCVY@1386|Bacillus	91061|Bacilli	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD2_k127_1788938_3	1169144.KB910935_gene2007	2.047e-100	341.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1V8HM@1239|Firmicutes,4IPM5@91061|Bacilli,1ZRCG@1386|Bacillus	91061|Bacilli	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD2_k127_1788938_2	1174504.AJTN02000185_gene134	1.801e-109	360.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HDH1@91061|Bacilli,1ZPYP@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	drrA	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
HKD2_k127_1794376_4	1403313.AXBR01000026_gene5188	9.213e-80	268.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,1ZFJ9@1386|Bacillus	91061|Bacilli	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
HKD2_k127_1794376_6	1403313.AXBR01000026_gene5189	2.689e-22	98.0	2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4HRG1@91061|Bacilli,1ZJ42@1386|Bacillus	91061|Bacilli	S	DNA-directed RNA polymerase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	EpuA
HKD2_k127_1794376_2	1403313.AXBR01000026_gene5190	2.959e-105	348.0	COG4786@1|root,COG4786@2|Bacteria,1TSYY@1239|Firmicutes,4HC6B@91061|Bacilli,1ZCIJ@1386|Bacillus	91061|Bacilli	N	flagellar basal body	flhP	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD2_k127_1794376_1	1403313.AXBR01000026_gene5191	4.245e-115	376.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,4HCKG@91061|Bacilli,1ZBEC@1386|Bacillus	91061|Bacilli	N	flagellar basal body	flhO	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD2_k127_1794376_0	1174504.AJTN02000207_gene3340	5.985e-201	628.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZC87@1386|Bacillus	91061|Bacilli	D	Rod shape-determining protein	mbl	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD2_k127_1794376_5	1174504.AJTN02000207_gene3341	3.095e-50	180.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,4HKIY@91061|Bacilli,1ZGY1@1386|Bacillus	91061|Bacilli	K	Stage III sporulation protein D	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
HKD2_k127_1794376_3	1403313.AXBR01000026_gene5194	4.381e-105	349.0	COG0739@1|root,COG0739@2|Bacteria,1V7CU@1239|Firmicutes,4HCZJ@91061|Bacilli,1ZC61@1386|Bacillus	91061|Bacilli	M	COG0739 Membrane proteins related to metalloendopeptidases	spoIIQ	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	ko:K06386	-	-	-	-	ko00000	1.A.34.1.1	-	-	Peptidase_M23
HKD2_k127_1794376_7	1403313.AXBR01000026_gene5195	8.426e-10	60.0	COG5652@1|root,COG5652@2|Bacteria,1VZIP@1239|Firmicutes,4I0XH@91061|Bacilli,1ZHW3@1386|Bacillus	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD2_k127_1794444_3	1232437.KL661971_gene4894	8.42e-35	138.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MKU8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
HKD2_k127_1794444_0	1502851.FG93_02805	2.154e-87	295.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,3JRXW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	glnQ	-	3.6.3.21	ko:K02028,ko:K10038	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.2	-	-	ABC_tran
HKD2_k127_1794444_1	1502851.FG93_02804	1.196e-76	262.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,2U2RK@28211|Alphaproteobacteria,3JUD6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HKD2_k127_1794444_2	1502851.FG93_02803	4.307e-73	256.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD2_k127_1794444_4	511680.BUTYVIB_00824	3.699e-28	122.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,4C1NG@830|Butyrivibrio	186801|Clostridia	K	FCD	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HKD2_k127_1794444_5	573370.DMR_41930	2.551e-11	68.0	COG0629@1|root,COG0629@2|Bacteria,1N7Y7@1224|Proteobacteria,42VDE@68525|delta/epsilon subdivisions,2WRWY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
HKD2_k127_1799613_3	1340434.AXVA01000004_gene2607	6.399e-10	61.0	COG3677@1|root,COG3677@2|Bacteria,1UYY4@1239|Firmicutes,4HDGD@91061|Bacilli,1ZD8V@1386|Bacillus	91061|Bacilli	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
HKD2_k127_1799613_2	1408303.JNJJ01000067_gene2284	1.036e-14	74.0	COG3677@1|root,COG3677@2|Bacteria,1UYY4@1239|Firmicutes,4HDGD@91061|Bacilli,1ZD8V@1386|Bacillus	91061|Bacilli	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
HKD2_k127_1799613_4	665952.HMPREF1015_00670	1.886e-07	55.0	COG0526@1|root,COG0526@2|Bacteria,1V1R4@1239|Firmicutes,4HFWU@91061|Bacilli,1ZBFR@1386|Bacillus	91061|Bacilli	CO	thiol-disulfide	ykuV	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD2_k127_1799613_1	1403313.AXBR01000021_gene3254	7.926e-114	370.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZC2N@1386|Bacillus	91061|Bacilli	P	COG0569 K transport systems, NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD2_k127_1799613_5	1385514.N782_03495	9.008e-07	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1799613_0	1403313.AXBR01000021_gene3253	3.227e-253	782.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZBCD@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD2_k127_1799791_13	1403313.AXBR01000008_gene562	7.431e-26	108.0	COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
HKD2_k127_1799791_7	1034347.CAHJ01000039_gene4626	3.413e-124	398.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus	91061|Bacilli	P	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD2_k127_1799791_11	1131730.BAVI_19619	4.938e-69	237.0	COG2839@1|root,COG2839@2|Bacteria,1V5DQ@1239|Firmicutes,4HJSF@91061|Bacilli,1ZQR9@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
HKD2_k127_1799791_10	1174504.AJTN02000181_gene273	2.093e-73	255.0	COG5521@1|root,COG5521@2|Bacteria,1V2MC@1239|Firmicutes,4HGIF@91061|Bacilli,1ZBMN@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1189)	yqgB	-	-	-	-	-	-	-	-	-	-	-	DUF1189
HKD2_k127_1799791_6	997296.PB1_15039	1.364e-124	419.0	COG0840@1|root,COG0840@2|Bacteria,1TZ8Z@1239|Firmicutes,4HBMM@91061|Bacilli,1ZDNK@1386|Bacillus	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	mcp4	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
HKD2_k127_1799791_15	1403313.AXBR01000008_gene566	1.913e-22	100.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	fimV	-	-	ko:K08086,ko:K15845	ko05120,map05120	-	-	-	ko00000,ko00001	-	-	-	LysM,TPR_19
HKD2_k127_1799791_1	1403313.AXBR01000008_gene567	2.656e-216	674.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H9S1@91061|Bacilli,1ZCV1@1386|Bacillus	91061|Bacilli	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
HKD2_k127_1799791_14	218284.CCDN010000001_gene778	3.213e-24	108.0	COG4709@1|root,COG4709@2|Bacteria,1VEVX@1239|Firmicutes,4HP5D@91061|Bacilli,1ZIJI@1386|Bacillus	91061|Bacilli	S	membrane	yqfX	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1799791_8	1403313.AXBR01000008_gene569	9.804e-87	292.0	COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,4HG86@91061|Bacilli,1ZDPA@1386|Bacillus	91061|Bacilli	S	Belongs to the 5'(3')-deoxyribonucleotidase family	yqfW	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
HKD2_k127_1799791_9	1403313.AXBR01000008_gene570	9.511e-74	249.0	COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,1ZG74@1386|Bacillus	91061|Bacilli	P	Belongs to the Fur family	zur	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02076	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD2_k127_1799791_4	1403313.AXBR01000008_gene571	2.078e-139	446.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli,1ZB0A@1386|Bacillus	91061|Bacilli	P	COG1108 ABC-type Mn2 Zn2 transport systems, permease components	zurM	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HKD2_k127_1799791_5	1403313.AXBR01000008_gene572	1.195e-133	428.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,1ZBS5@1386|Bacillus	91061|Bacilli	P	'COG1121 ABC-type Mn Zn transport systems, ATPase component'	zurA	-	-	ko:K02074,ko:K09817	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
HKD2_k127_1799791_3	1403313.AXBR01000008_gene574	2.407e-163	517.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,1ZBYQ@1386|Bacillus	91061|Bacilli	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
HKD2_k127_1799791_0	1403313.AXBR01000008_gene575	2.471e-229	715.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,1ZDG5@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures	cshB	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
HKD2_k127_1799791_12	1403313.AXBR01000008_gene577	4.652e-31	130.0	2ECSV@1|root,336QF@2|Bacteria,1VFWG@1239|Firmicutes,4HP8Y@91061|Bacilli,1ZIWT@1386|Bacillus	91061|Bacilli	S	YqfQ-like protein	yqfQ	-	-	-	-	-	-	-	-	-	-	-	YqfQ
HKD2_k127_1799791_2	1403313.AXBR01000008_gene578	1.01e-179	565.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus	91061|Bacilli	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
HKD2_k127_1837446_6	743719.PaelaDRAFT_0626	9.252e-06	51.0	2EMTC@1|root,33FFQ@2|Bacteria,1VPA9@1239|Firmicutes,4HRY3@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1837446_0	1405.DJ92_3068	8.509e-229	717.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,1ZDGT@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HKD2_k127_1837446_1	345219.Bcoa_0798	1.059e-42	160.0	2EH4F@1|root,33AWE@2|Bacteria,1UC9C@1239|Firmicutes,4HYKA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1837446_5	1127131.WEISSC39_09690	6.789e-07	51.0	COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,4AYX7@81850|Leuconostocaceae	91061|Bacilli	F	DNA/RNA non-specific endonuclease	endA	-	-	ko:K15051	-	-	-	-	ko00000	-	-	-	Endonuclea_NS_2,Endonuclease_NS
HKD2_k127_1837446_7	1007103.AFHW01000190_gene1142	1.506e-05	49.0	29KKJ@1|root,307HW@2|Bacteria,1U1QG@1239|Firmicutes,4IB6W@91061|Bacilli,273T5@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1837446_4	1305836.AXVE01000015_gene3040	3.248e-07	52.0	2936E@1|root,2ZD0R@2|Bacteria,1W2G2@1239|Firmicutes,4I0IS@91061|Bacilli,26I0E@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_183751_1	1340434.AXVA01000022_gene3935	6.092e-32	127.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1
HKD2_k127_183751_2	665959.HMPREF1013_05292	9.686e-12	73.0	29RU0@1|root,30CXX@2|Bacteria,1UAIR@1239|Firmicutes,4IKX7@91061|Bacilli,1ZI65@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_183751_3	1121091.AUMP01000032_gene3061	2.889e-07	54.0	COG1525@1|root,COG1525@2|Bacteria,1V46V@1239|Firmicutes,4HHJ1@91061|Bacilli	91061|Bacilli	L	RNA catabolic process	yokF	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
HKD2_k127_183751_0	272558.10176540	2.063e-95	337.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	mcpB1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
HKD2_k127_1839910_0	1403313.AXBR01000009_gene786	5.351e-258	797.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
HKD2_k127_1839910_1	1403313.AXBR01000009_gene787	6.348e-187	587.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,1ZARK@1386|Bacillus	91061|Bacilli	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HKD2_k127_1839910_3	1403313.AXBR01000009_gene788	1.101e-90	305.0	COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1ZGER@1386|Bacillus	91061|Bacilli	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD2_k127_1839910_2	1403313.AXBR01000009_gene789	3.808e-142	454.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,1ZCR0@1386|Bacillus	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
HKD2_k127_1841208_2	1403313.AXBR01000009_gene841	1.041e-307	949.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD2_k127_1841208_4	1403313.AXBR01000009_gene843	1.931e-67	231.0	COG3766@1|root,COG3766@2|Bacteria,1V6MT@1239|Firmicutes,4HH4E@91061|Bacilli,1ZG9Y@1386|Bacillus	91061|Bacilli	S	membrane	yshE	-	-	ko:K08989	-	-	-	-	ko00000	-	-	-	DUF350
HKD2_k127_1841208_0	1174504.AJTN02000191_gene4261	0.0	1157.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1ZBJV@1386|Bacillus	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD2_k127_1841208_1	1403313.AXBR01000009_gene846	8.257e-312	963.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus	91061|Bacilli	L	COG1796 DNA polymerase IV (family X)	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
HKD2_k127_1841208_7	1294265.JCM21738_1787	5.188e-05	48.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD2_k127_1841208_3	1403313.AXBR01000009_gene847	8.112e-84	282.0	COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,1ZDGZ@1386|Bacillus	91061|Bacilli	S	membrane protein, required for colicin V production	yshB	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
HKD2_k127_1841208_5	1403313.AXBR01000009_gene848	7.038e-32	126.0	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,1ZHZX@1386|Bacillus	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HKD2_k127_1841208_6	1340434.AXVA01000010_gene5484	2.976e-05	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1884404_0	997296.PB1_00330	1.643e-215	673.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HDMN@91061|Bacilli,1ZPWM@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_1,TPR_2
HKD2_k127_1884404_1	997296.PB1_00325	9.934e-212	666.0	COG0438@1|root,COG0438@2|Bacteria,1UMR3@1239|Firmicutes,4HDH9@91061|Bacilli	91061|Bacilli	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1,TPR_8
HKD2_k127_1884404_3	1089548.KI783301_gene2405	1.19e-34	135.0	2E9SM@1|root,333YT@2|Bacteria,1VH0N@1239|Firmicutes,4HNSD@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1884404_2	349161.Dred_1382	1.668e-59	209.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD2_k127_194823_0	1403313.AXBR01000002_gene4248	0.0	1033.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus	91061|Bacilli	P	COG2217 Cation transport ATPase	zosA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
HKD2_k127_194823_12	1444310.JANV01000013_gene4251	2.493e-07	52.0	29S58@1|root,30D9S@2|Bacteria,1UB1M@1239|Firmicutes,4IMEH@91061|Bacilli,1ZJYU@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_194823_6	1403313.AXBR01000002_gene4249	1.329e-116	381.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD2_k127_194823_11	1294265.JCM21738_463	2.427e-24	104.0	COG4840@1|root,COG4840@2|Bacteria,1VEYR@1239|Firmicutes,4HNKK@91061|Bacilli,1ZJ0U@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0435 family	yfkK	-	-	-	-	-	-	-	-	-	-	-	DUF1128
HKD2_k127_194823_10	1403313.AXBR01000002_gene4254	7.104e-31	123.0	COG5460@1|root,COG5460@2|Bacteria,1VNAE@1239|Firmicutes,4HRC9@91061|Bacilli,1ZIV1@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
HKD2_k127_194823_3	1403313.AXBR01000002_gene4255	8.78e-149	472.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZBQI@1386|Bacillus	91061|Bacilli	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD2_k127_194823_9	1403313.AXBR01000002_gene4257	9.695e-43	158.0	2E8H8@1|root,332VF@2|Bacteria,1VI1H@1239|Firmicutes,4HQ7K@91061|Bacilli,1ZIED@1386|Bacillus	91061|Bacilli	S	Late competence development protein ComFB	-	-	-	ko:K02241	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComFB
HKD2_k127_194823_7	1403313.AXBR01000002_gene4258	5.569e-102	336.0	COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,1ZB4F@1386|Bacillus	91061|Bacilli	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
HKD2_k127_194823_5	1174504.AJTN02000232_gene2457	8.785e-127	409.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus	91061|Bacilli	N	flagellar motor	motA	GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
HKD2_k127_194823_4	1403313.AXBR01000002_gene4260	7.431e-135	439.0	COG3180@1|root,COG3180@2|Bacteria,1UVXN@1239|Firmicutes,4HEJT@91061|Bacilli,1ZQPP@1386|Bacillus	91061|Bacilli	S	Transition state regulatory protein AbrB	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
HKD2_k127_194823_2	1174504.AJTN02000232_gene2451	1.422e-168	534.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HC52@91061|Bacilli,1ZCN2@1386|Bacillus	91061|Bacilli	D	Rod-share determining protein MreBH	mreBH	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD2_k127_194823_1	1034347.CAHJ01000068_gene2589	5.618e-179	572.0	COG0642@1|root,COG2205@2|Bacteria,1TRAB@1239|Firmicutes,4HAXE@91061|Bacilli,1ZEN9@1386|Bacillus	91061|Bacilli	T	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
HKD2_k127_194823_8	1034347.CAHJ01000068_gene2590	1.436e-95	316.0	28MY0@1|root,2ZB4Y@2|Bacteria,1V0KB@1239|Firmicutes,4HE2C@91061|Bacilli,1ZE6E@1386|Bacillus	91061|Bacilli	-	-	ywdD	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1962064_1	1340434.AXVA01000008_gene3684	5.225e-63	219.0	COG1309@1|root,COG1309@2|Bacteria,1TP0U@1239|Firmicutes,4HE9Q@91061|Bacilli,1ZBMJ@1386|Bacillus	91061|Bacilli	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_1962064_0	1117379.BABA_20286	6.934e-257	799.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_1962064_2	1196031.ALEG01000061_gene2181	1.166e-41	154.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,1ZB4N@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_1974793_8	1385511.N783_07535	1.026e-21	95.0	COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,4HATV@91061|Bacilli,2Y9BW@289201|Pontibacillus	91061|Bacilli	S	Choloylglycine hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
HKD2_k127_1974793_10	1347086.CCBA010000031_gene966	0.0002316	45.0	2DGN4@1|root,2ZWMV@2|Bacteria,1W6QT@1239|Firmicutes,4I0RX@91061|Bacilli,1ZJJ1@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1974793_1	1243664.CAVL020000054_gene3112	4.876e-318	982.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,1ZAPW@1386|Bacillus	91061|Bacilli	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD2_k127_1974793_4	1132442.KB889752_gene2772	1.957e-91	309.0	COG4990@1|root,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HK8M@91061|Bacilli,1ZDKM@1386|Bacillus	91061|Bacilli	NU	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HKD2_k127_1974793_5	1034347.CAHJ01000027_gene3839	8.71e-45	164.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_1974793_0	345219.Bcoa_0583	0.0	1154.0	COG1196@1|root,COG4717@1|root,COG1196@2|Bacteria,COG4717@2|Bacteria,1UBN9@1239|Firmicutes,4IN2W@91061|Bacilli,1ZMPW@1386|Bacillus	91061|Bacilli	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
HKD2_k127_1974793_2	1123284.KB899044_gene560	3.759e-197	621.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,26NWI@186821|Sporolactobacillaceae	91061|Bacilli	L	Calcineurin-like phosphoesterase	yhaO	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
HKD2_k127_1974793_7	1403313.AXBR01000013_gene1554	1.717e-28	118.0	29RJ6@1|root,30CN9@2|Bacteria,1UA4M@1239|Firmicutes,4IKEV@91061|Bacilli,1ZGSF@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1974793_9	1321778.HMPREF1982_03663	2.981e-10	64.0	COG4902@1|root,COG4902@2|Bacteria,1UNE2@1239|Firmicutes,25H1F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
HKD2_k127_1974793_6	1384049.CD29_03955	1.75e-32	128.0	2E5KF@1|root,330BM@2|Bacteria,1VEYE@1239|Firmicutes,4HNR3@91061|Bacilli,3IZQP@400634|Lysinibacillus	91061|Bacilli	S	Small, acid-soluble spore proteins, alpha/beta type	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HKD2_k127_1974793_3	1132442.KB889752_gene1835	8.682e-114	370.0	COG1041@1|root,COG1041@2|Bacteria,1TRH9@1239|Firmicutes,4HCHR@91061|Bacilli,1ZBCC@1386|Bacillus	91061|Bacilli	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
HKD2_k127_1982700_5	1403313.AXBR01000009_gene904	5.092e-157	497.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,1ZB3M@1386|Bacillus	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD2_k127_1982700_4	1403313.AXBR01000009_gene903	9.106e-164	520.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,1ZC5V@1386|Bacillus	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
HKD2_k127_1982700_3	1403313.AXBR01000009_gene902	5.52e-182	572.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,1ZB3D@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	iYO844.BSU29190	PFK
HKD2_k127_1982700_0	1403313.AXBR01000009_gene901	4.925e-314	969.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HKD2_k127_1982700_8	1403313.AXBR01000009_gene900	1.082e-51	186.0	COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,4HNQ9@91061|Bacilli,1ZQRP@1386|Bacillus	91061|Bacilli	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	fxsA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
HKD2_k127_1982700_1	1403313.AXBR01000009_gene899	7.474e-298	918.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,1ZBY7@1386|Bacillus	91061|Bacilli	C	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
HKD2_k127_1982700_2	1174504.AJTN02000257_gene1519	3.562e-230	717.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli,1ZBPW@1386|Bacillus	91061|Bacilli	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
HKD2_k127_1982700_6	1403313.AXBR01000009_gene897	2.906e-146	478.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,4HC6G@91061|Bacilli,1ZBXK@1386|Bacillus	91061|Bacilli	S	sporulation integral membrane protein YtvI	ytvI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD2_k127_1982700_7	1403313.AXBR01000009_gene896	7.238e-67	230.0	COG2707@1|root,COG2707@2|Bacteria,1VBA7@1239|Firmicutes,4HKC9@91061|Bacilli,1ZG6J@1386|Bacillus	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF441
HKD2_k127_1982700_9	1403313.AXBR01000009_gene895	2.686e-50	180.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1ZBAY@1386|Bacillus	91061|Bacilli	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD2_k127_1984724_1	1132442.KB889753_gene123	6.038e-190	594.0	COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,4HBEX@91061|Bacilli,1ZBHT@1386|Bacillus	91061|Bacilli	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	cysI	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HKD2_k127_1984724_5	666686.B1NLA3E_19090	7.231e-45	168.0	COG0196@1|root,COG0196@2|Bacteria,1VXBN@1239|Firmicutes,4HXKJ@91061|Bacilli,1ZHUP@1386|Bacillus	91061|Bacilli	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavokinase
HKD2_k127_1984724_6	720555.BATR1942_01180	9.115e-33	130.0	COG0196@1|root,COG0196@2|Bacteria,1U8V1@1239|Firmicutes,4IITF@91061|Bacilli,1ZJM2@1386|Bacillus	91061|Bacilli	H	riboflavin kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1984724_9	796606.BMMGA3_09040	2.679e-13	71.0	2DC8S@1|root,2ZD9J@2|Bacteria,1UB2T@1239|Firmicutes,4IMFH@91061|Bacilli,1ZK1E@1386|Bacillus	91061|Bacilli	S	Uncharacterized small protein (DUF2292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2292
HKD2_k127_1984724_3	1132442.KB889752_gene1488	8.137e-151	482.0	COG2175@1|root,COG2175@2|Bacteria,1V8TM@1239|Firmicutes,4HK2N@91061|Bacilli,1ZDYH@1386|Bacillus	91061|Bacilli	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K22303	-	-	-	-	ko00000,ko01000	-	-	-	TauD
HKD2_k127_1984724_2	1132442.KB889752_gene1236	2.458e-158	501.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_1984724_4	1132442.KB889752_gene1237	5.085e-132	425.0	COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HCJ7@91061|Bacilli,1ZBH6@1386|Bacillus	91061|Bacilli	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD2_k127_1984724_10	306281.AJLK01000103_gene3375	4.695e-10	60.0	COG2141@1|root,COG2141@2|Bacteria,1GBUI@1117|Cyanobacteria	1117|Cyanobacteria	C	TIGRFAM Nitrilotriacetate monooxygenase component A pristinamycin IIA synthase subunit A	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HKD2_k127_1984724_0	1132442.KB889752_gene1238	3.908e-284	874.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	yxeK	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_1984724_7	1132442.KB889752_gene1239	1.013e-31	125.0	COG0715@1|root,COG0715@2|Bacteria,1V9ZY@1239|Firmicutes,4HTB1@91061|Bacilli,1ZDC2@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
HKD2_k127_1986483_7	1403313.AXBR01000007_gene354	3.73e-149	476.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,1ZC9C@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD2_k127_1986483_21	1174504.AJTN02000249_gene822	2.604e-45	166.0	COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,4HKTN@91061|Bacilli,1ZH0S@1386|Bacillus	91061|Bacilli	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	aroH	GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
HKD2_k127_1986483_3	1403313.AXBR01000007_gene352	4.575e-183	578.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus	91061|Bacilli	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_1986483_4	1403313.AXBR01000007_gene351	2.707e-165	526.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus	91061|Bacilli	E	prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22610	ACT,PDH
HKD2_k127_1986483_0	1403313.AXBR01000007_gene350	5.181e-207	650.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HKD2_k127_1986483_1	1403313.AXBR01000007_gene349	7.678e-192	606.0	COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	ypiA	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
HKD2_k127_1986483_16	1403313.AXBR01000007_gene348	5.685e-96	316.0	COG5582@1|root,COG5582@2|Bacteria,1V5KV@1239|Firmicutes,4HEE0@91061|Bacilli,1ZB4J@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0302 family	ypiB	-	-	-	-	-	-	-	-	-	-	-	IDEAL,UPF0302
HKD2_k127_1986483_20	1403313.AXBR01000007_gene347	2.76e-47	173.0	2CSPZ@1|root,32SRK@2|Bacteria,1VBS0@1239|Firmicutes,4HKXQ@91061|Bacilli,1ZI4R@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2487)	ypiF	-	-	-	-	-	-	-	-	-	-	-	DUF2487
HKD2_k127_1986483_17	1403313.AXBR01000007_gene346	5.854e-90	299.0	COG0723@1|root,COG0723@2|Bacteria,1TQUH@1239|Firmicutes,4HBX1@91061|Bacilli,1ZFNX@1386|Bacillus	91061|Bacilli	C	Menaquinol-cytochrome c reductase	qcrA	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CytB6-F_Fe-S,Rieske
HKD2_k127_1986483_10	1403313.AXBR01000007_gene345	1.685e-139	443.0	COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,4H9XV@91061|Bacilli,1ZB3U@1386|Bacillus	91061|Bacilli	C	COG1290 Cytochrome b subunit of the bc complex	qcrB	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
HKD2_k127_1986483_9	1403313.AXBR01000007_gene344	6.667e-147	467.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,1ZCZW@1386|Bacillus	91061|Bacilli	C	Menaquinol-cytochrome c reductase cytochrome b c subunit	qcrC	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrome_CBB3
HKD2_k127_1986483_14	1403313.AXBR01000007_gene343	1.505e-99	327.0	COG4347@1|root,COG4347@2|Bacteria,1V1NI@1239|Firmicutes,4HFTW@91061|Bacilli,1ZFJF@1386|Bacillus	91061|Bacilli	S	membrane	ypjA	-	-	-	-	-	-	-	-	-	-	-	DUF1405
HKD2_k127_1986483_15	1403313.AXBR01000007_gene342	4.793e-97	323.0	28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus	91061|Bacilli	S	sporulation protein	ypjB	-	-	-	-	-	-	-	-	-	-	-	Spore_YpjB
HKD2_k127_1986483_22	1385514.N782_03495	4.353e-09	59.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1986483_12	1403313.AXBR01000007_gene341	1.125e-113	369.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,1ZD1M@1386|Bacillus	91061|Bacilli	S	Zn-dependent protease	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HKD2_k127_1986483_6	1403313.AXBR01000007_gene340	4.304e-150	479.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,1ZBUC@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	ypjC	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD2_k127_1986483_19	1403313.AXBR01000007_gene339	2.059e-53	189.0	COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,4HISK@91061|Bacilli,1ZH1U@1386|Bacillus	91061|Bacilli	S	Nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
HKD2_k127_1986483_8	1403313.AXBR01000007_gene338	2.283e-148	471.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,1ZAWD@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22490	DapB_C,DapB_N
HKD2_k127_1986483_18	1403313.AXBR01000007_gene337	5.991e-69	235.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,4HH64@91061|Bacilli,1ZGAF@1386|Bacillus	91061|Bacilli	G	methylglyoxal synthase	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HKD2_k127_1986483_13	1403313.AXBR01000007_gene336	3.661e-113	368.0	COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus	91061|Bacilli	S	proteins, LmbE homologs	ypjG	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
HKD2_k127_1986483_2	1403313.AXBR01000007_gene335	2.268e-190	600.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus	91061|Bacilli	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD2_k127_1986483_11	1499685.CCFJ01000046_gene3627	2.093e-114	381.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,1ZC20@1386|Bacillus	91061|Bacilli	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HKD2_k127_1986483_5	1403313.AXBR01000007_gene333	2.787e-157	501.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HKD2_k127_1989779_29	1403313.AXBR01000021_gene3130	1.184e-86	290.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HKD2_k127_1989779_8	1403313.AXBR01000021_gene3131	2.438e-203	638.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD2_k127_1989779_36	1403313.AXBR01000021_gene3132	8.825e-26	108.0	COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,1ZIVD@1386|Bacillus	91061|Bacilli	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
HKD2_k127_1989779_25	1403313.AXBR01000021_gene3133	1.512e-105	345.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,1ZBZI@1386|Bacillus	91061|Bacilli	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15680	Guanylate_kin
HKD2_k127_1989779_34	1403313.AXBR01000021_gene3134	6.826e-42	154.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,4HKDP@91061|Bacilli,1ZHVQ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0296 family	ylzA	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HKD2_k127_1989779_17	1403313.AXBR01000021_gene3135	1.573e-117	385.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus	91061|Bacilli	S	stress-induced protein	yloC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD2_k127_1989779_2	1403313.AXBR01000021_gene3136	0.0	1401.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus	91061|Bacilli	P	COG0474 Cation transport ATPase	yloB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	iYO844.BSU15650	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD2_k127_1989779_3	1403313.AXBR01000021_gene3138	5.136e-292	905.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus	91061|Bacilli	K	RNA-binding protein homologous to eukaryotic snRNP	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
HKD2_k127_1989779_15	1243664.CAVL020000016_gene2041	4.275e-121	393.0	COG1119@1|root,COG1119@2|Bacteria,1TRR4@1239|Firmicutes,4HB4U@91061|Bacilli,1ZBUE@1386|Bacillus	91061|Bacilli	P	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HKD2_k127_1989779_31	86416.Clopa_3246	1.297e-61	229.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,36FHQ@31979|Clostridiaceae	186801|Clostridia	FP	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
HKD2_k127_1989779_24	1403313.AXBR01000021_gene3139	1.687e-106	348.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,1ZASD@1386|Bacillus	91061|Bacilli	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15560	Pribosyltran
HKD2_k127_1989779_23	1403313.AXBR01000021_gene3140	7.566e-107	351.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,1ZB1I@1386|Bacillus	91061|Bacilli	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD2_k127_1989779_10	1403313.AXBR01000021_gene3141	7.019e-173	545.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,1ZBNC@1386|Bacillus	91061|Bacilli	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15540	DHO_dh
HKD2_k127_1989779_16	1403313.AXBR01000021_gene3142	6.029e-119	386.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli,1ZBJI@1386|Bacillus	91061|Bacilli	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iYO844.BSU15530	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
HKD2_k127_1989779_0	1403313.AXBR01000021_gene3143	0.0	1925.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus	91061|Bacilli	F	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD2_k127_1989779_9	1403313.AXBR01000021_gene3144	3.542e-200	628.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,1ZB7G@1386|Bacillus	91061|Bacilli	F	Carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15510	CPSase_sm_chain,GATase
HKD2_k127_1989779_5	1403313.AXBR01000021_gene3145	2.008e-231	721.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus	91061|Bacilli	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD2_k127_1989779_18	935837.JAEK01000005_gene4552	1.553e-116	385.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,1ZBHG@1386|Bacillus	91061|Bacilli	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
HKD2_k127_1989779_27	1403313.AXBR01000021_gene3148	4.18e-91	301.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,1ZB3P@1386|Bacillus	91061|Bacilli	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD2_k127_1989779_11	1403313.AXBR01000021_gene3149	8.935e-169	533.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1ZC3M@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD2_k127_1989779_32	545693.BMQ_4259	8.573e-61	213.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,1ZGBF@1386|Bacillus	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HKD2_k127_1989779_1	1403313.AXBR01000021_gene3151	0.0	1672.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus	91061|Bacilli	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
HKD2_k127_1989779_28	1403313.AXBR01000021_gene3152	2.118e-89	297.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,1ZFNB@1386|Bacillus	91061|Bacilli	D	Cell division initiation protein	divIVA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
HKD2_k127_1989779_20	1403313.AXBR01000021_gene3153	1.035e-112	368.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,1ZC97@1386|Bacillus	91061|Bacilli	S	conserved protein, contains S4-like domain	ylmH	-	-	-	-	-	-	-	-	-	-	-	S4
HKD2_k127_1989779_35	997296.PB1_01480	1.653e-31	124.0	COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,1ZHUZ@1386|Bacillus	91061|Bacilli	S	membrane	ylmG	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
HKD2_k127_1989779_30	1403313.AXBR01000021_gene3155	1.111e-73	250.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,1ZGE0@1386|Bacillus	91061|Bacilli	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HKD2_k127_1989779_26	1403313.AXBR01000021_gene3156	1.011e-103	340.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,1ZARM@1386|Bacillus	91061|Bacilli	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD2_k127_1989779_19	1174504.AJTN02000161_gene422	1.028e-112	369.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,1ZBZZ@1386|Bacillus	91061|Bacilli	S	Belongs to the multicopper oxidase YfiH RL5 family	ylmD	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HKD2_k127_1989779_33	1403313.AXBR01000021_gene3159	4.083e-42	156.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,4HNT3@91061|Bacilli,1ZI0Y@1386|Bacillus	91061|Bacilli	S	sporulation protein	ylmC	-	-	-	-	-	-	-	-	-	-	-	PRC
HKD2_k127_1989779_13	1403313.AXBR01000021_gene3160	1.928e-153	487.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,4H9MN@91061|Bacilli,1ZB53@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD2_k127_1989779_14	1499680.CCFE01000024_gene2831	3.465e-132	424.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,4H9PG@91061|Bacilli,1ZBKD@1386|Bacillus	91061|Bacilli	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD2_k127_1989779_21	1403313.AXBR01000021_gene3162	7.708e-111	366.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,4HDX6@91061|Bacilli,1ZAV2@1386|Bacillus	91061|Bacilli	M	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR	spoIIGA	GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
HKD2_k127_1989779_37	1340434.AXVA01000010_gene5484	3.364e-05	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_1989779_7	1403313.AXBR01000021_gene3163	9.69e-207	647.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HKD2_k127_1989779_4	1403313.AXBR01000021_gene3164	1.086e-233	727.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus	91061|Bacilli	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	DUF3484,FtsA,SHS2_FTSA
HKD2_k127_1989779_22	1403313.AXBR01000021_gene3168	2.096e-110	361.0	COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,1ZDSW@1386|Bacillus	91061|Bacilli	D	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex	divIB	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
HKD2_k127_1989779_12	1403313.AXBR01000021_gene3169	2.374e-154	492.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,1ZC3F@1386|Bacillus	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
HKD2_k127_1989779_6	1403313.AXBR01000021_gene3170	7.971e-219	681.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBY5@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD2_k127_1998246_1	1403313.AXBR01000021_gene3109	0.0	1063.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD2_k127_1998246_5	1403313.AXBR01000021_gene3110	7.135e-126	405.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,1ZAPM@1386|Bacillus	91061|Bacilli	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HKD2_k127_1998246_9	1403313.AXBR01000021_gene3111	1.471e-34	134.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,1ZHY7@1386|Bacillus	91061|Bacilli	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD2_k127_1998246_6	1403313.AXBR01000021_gene3112	8.207e-125	403.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
HKD2_k127_1998246_4	1403313.AXBR01000021_gene3113	2.158e-148	475.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HKD2_k127_1998246_3	1403313.AXBR01000021_gene3114	1.133e-168	534.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,1ZBW8@1386|Bacillus	91061|Bacilli	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HKD2_k127_1998246_7	1403313.AXBR01000021_gene3115	6.506e-94	310.0	COG1349@1|root,COG1349@2|Bacteria,1V3MJ@1239|Firmicutes,4HHFC@91061|Bacilli,1ZAV1@1386|Bacillus	91061|Bacilli	K	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism	fapR	-	-	-	-	-	-	-	-	-	-	-	4HBT,HTH_DeoR,MaoC_dehydratas
HKD2_k127_1998246_0	1403313.AXBR01000021_gene3116	0.0	1150.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus	91061|Bacilli	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HKD2_k127_1998246_2	1403313.AXBR01000021_gene3119	2.234e-284	881.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus	91061|Bacilli	S	kinase related to dihydroxyacetone kinase	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
HKD2_k127_1998246_8	1403313.AXBR01000021_gene3120	9.84e-66	225.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,1ZG6I@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yloU	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD2_k127_1998246_10	665959.HMPREF1013_00373	3.791e-29	117.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,1ZIVY@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD2_k127_2016221_8	1117379.BABA_06341	7.298e-06	50.0	2EEB8@1|root,3385J@2|Bacteria,1VM15@1239|Firmicutes,4HPJI@91061|Bacilli,1ZJ91@1386|Bacillus	91061|Bacilli	S	Spore germination protein GerPE	gerPE	-	-	ko:K06303	-	-	-	-	ko00000	-	-	-	GerPE
HKD2_k127_2016221_6	235909.GK0687	3.904e-11	65.0	2C5QJ@1|root,33C5U@2|Bacteria,1VK5Y@1239|Firmicutes,4HR2R@91061|Bacilli,1WH01@129337|Geobacillus	91061|Bacilli	S	Spore gernimation protein GerPD	gerPD	-	-	ko:K06302	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_2016221_2	1403313.AXBR01000023_gene2374	2.227e-72	249.0	2EBJR@1|root,335K6@2|Bacteria,1VF1J@1239|Firmicutes,4HNKG@91061|Bacilli,1ZI2K@1386|Bacillus	91061|Bacilli	S	Spore germination protein	gerPC	-	-	ko:K06301	-	-	-	-	ko00000	-	-	-	GerPC
HKD2_k127_2016221_5	1403313.AXBR01000023_gene2373	5.934e-20	90.0	2EBHF@1|root,335HY@2|Bacteria,1VHMW@1239|Firmicutes,4HPZZ@91061|Bacilli,1ZIW2@1386|Bacillus	91061|Bacilli	S	cell differentiation	gerPB	-	-	ko:K06300	-	-	-	-	ko00000	-	-	-	GerPB
HKD2_k127_2016221_4	1403313.AXBR01000023_gene2372	7.044e-30	120.0	2DPJX@1|root,332FH@2|Bacteria,1VF9T@1239|Firmicutes,4HPCA@91061|Bacilli,1ZIV2@1386|Bacillus	91061|Bacilli	S	Spore germination protein	gerPA	GO:0000003,GO:0008150,GO:0009847,GO:0019954,GO:0030436,GO:0032502,GO:0043934	-	ko:K06299	-	-	-	-	ko00000	-	-	-	gerPA
HKD2_k127_2016221_3	1403313.AXBR01000023_gene2368	6.161e-43	160.0	2CKSS@1|root,32W2Q@2|Bacteria,1VB9W@1239|Firmicutes,4HMC5@91061|Bacilli,1ZHSY@1386|Bacillus	91061|Bacilli	S	UPF0344 protein	yisL	-	-	-	-	-	-	-	-	-	-	-	DUF1516
HKD2_k127_2016221_1	1403313.AXBR01000023_gene2367	2.105e-86	288.0	2E4ZB@1|root,32ZT1@2|Bacteria,1VHAC@1239|Firmicutes,4HQBP@91061|Bacilli,1ZD5D@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2777)	yisN	-	-	-	-	-	-	-	-	-	-	-	DUF2777
HKD2_k127_2016221_0	1403313.AXBR01000023_gene2366	0.0	1128.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,1ZBY8@1386|Bacillus	91061|Bacilli	E	Asparagine synthase	asnO	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD2_k127_2016221_7	1340434.AXVA01000010_gene5484	4.127e-06	48.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2029646_0	1117379.BABA_13412	2.071e-164	519.0	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,4HD04@91061|Bacilli,1ZDKD@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
HKD2_k127_2029646_1	1347086.CCBA010000019_gene1047	1.321e-84	283.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZFRC@1386|Bacillus	91061|Bacilli	U	Peptidase S24-like	sipS	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD2_k127_2029646_4	634956.Geoth_0518	4.279e-26	112.0	2E9PH@1|root,3092W@2|Bacteria,1U4CJ@1239|Firmicutes,4HZUZ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2029646_2	1243664.CAVL020000024_gene2937	1.341e-41	153.0	COG0346@1|root,COG0346@2|Bacteria,1V3YM@1239|Firmicutes,4HH9D@91061|Bacilli,1ZG2I@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
HKD2_k127_206007_3	1345697.M493_16440	3.987e-38	153.0	COG0791@1|root,COG2247@1|root,COG0791@2|Bacteria,COG2247@2|Bacteria,1V2SY@1239|Firmicutes,4HGDM@91061|Bacilli,1WHRC@129337|Geobacillus	91061|Bacilli	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
HKD2_k127_206007_4	1122985.HMPREF1991_00671	2.973e-06	55.0	COG1404@1|root,COG1404@2|Bacteria,4P1G4@976|Bacteroidetes,2FX6D@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Peptidase_S8_N
HKD2_k127_206007_1	1267580.AF6_2535	5.049e-131	423.0	COG3550@1|root,COG3550@2|Bacteria,1VJ1Y@1239|Firmicutes,4HKJY@91061|Bacilli	91061|Bacilli	S	peptidyl-serine autophosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
HKD2_k127_206007_2	235909.GK3291	2.483e-121	393.0	2DBHY@1|root,2Z9DM@2|Bacteria,1UPS2@1239|Firmicutes,4IV9U@91061|Bacilli	91061|Bacilli	S	HIRAN	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
HKD2_k127_206007_0	1121289.JHVL01000012_gene1738	1.132e-149	476.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,36EIH@31979|Clostridiaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD2_k127_2060816_0	1347369.CCAD010000035_gene1070	8.146e-178	564.0	COG1680@1|root,COG1680@2|Bacteria,1V2AR@1239|Firmicutes,4HGF0@91061|Bacilli,1ZI9D@1386|Bacillus	91061|Bacilli	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD2_k127_2060816_2	1132442.KB889752_gene2767	2.251e-64	224.0	COG0640@1|root,COG0640@2|Bacteria,1VCMI@1239|Firmicutes,4HJJ5@91061|Bacilli,1ZHF7@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HKD2_k127_2060816_1	1132442.KB889752_gene2766	9.326e-102	341.0	COG1073@1|root,COG1073@2|Bacteria,1TSFY@1239|Firmicutes,4HG5Y@91061|Bacilli,1ZFTK@1386|Bacillus	91061|Bacilli	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD2_k127_2060816_3	1121091.AUMP01000004_gene2395	3.692e-48	182.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,4HEYB@91061|Bacilli	91061|Bacilli	S	Putative membrane peptidase family (DUF2324)	yhfC	-	-	-	-	-	-	-	-	-	-	-	DUF2324
HKD2_k127_2060816_4	1403313.AXBR01000014_gene2257	6.382e-47	171.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HA1X@91061|Bacilli,1ZCDN@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	gltC	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K09681	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HKD2_k127_2067370_0	666686.B1NLA3E_11330	1.169e-264	815.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA8B@91061|Bacilli,1ZAPG@1386|Bacillus	91061|Bacilli	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
HKD2_k127_2067370_1	666686.B1NLA3E_11335	1.869e-232	721.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,4HD3B@91061|Bacilli,1ZDTC@1386|Bacillus	91061|Bacilli	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
HKD2_k127_2086712_1	1340434.AXVA01000003_gene2399	1.311e-179	568.0	COG1075@1|root,COG1075@2|Bacteria,1VIWR@1239|Firmicutes,4HQU4@91061|Bacilli,1ZKJQ@1386|Bacillus	91061|Bacilli	S	Lecithin:cholesterol acyltransferase	est	-	-	-	-	-	-	-	-	-	-	-	LCAT,PPC
HKD2_k127_2086712_0	666686.B1NLA3E_09465	1.543e-184	580.0	28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,1ZCDZ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3231
HKD2_k127_2086712_2	1132442.KB889752_gene3872	2.854e-96	316.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS_1	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD2_k127_208785_5	1403313.AXBR01000008_gene539	1.711e-08	55.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqgX	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HKD2_k127_208785_3	1218173.BALCAV_0221005	9.035e-43	162.0	COG0824@1|root,COG0824@2|Bacteria,1V5WJ@1239|Firmicutes,4HHKT@91061|Bacilli,1ZGHW@1386|Bacillus	91061|Bacilli	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
HKD2_k127_208785_4	1174504.AJTN02000181_gene248	6.662e-37	140.0	2E1GI@1|root,32WUX@2|Bacteria,1VB9C@1239|Firmicutes,4HNTC@91061|Bacilli,1ZQN9@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2626)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2626
HKD2_k127_208785_1	997296.PB1_14879	3.179e-94	316.0	COG2345@1|root,COG2345@2|Bacteria,1UYQM@1239|Firmicutes,4HAZZ@91061|Bacilli,1ZC2X@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase,HTH_20
HKD2_k127_208785_0	1174504.AJTN02000181_gene245	1.248e-158	506.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZBK5@1386|Bacillus	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	comGA	-	-	ko:K02243	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.14.1	-	-	T2SSE
HKD2_k127_208785_2	1403313.AXBR01000008_gene533	4.677e-70	243.0	COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus	91061|Bacilli	NU	COG1459 Type II secretory pathway, component PulF	comGB	-	-	ko:K02244	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.14.1	-	-	T2SSF
HKD2_k127_21155_2	243164.DET1501	6.684e-29	123.0	COG0716@1|root,COG0716@2|Bacteria,2GAZ4@200795|Chloroflexi,34DME@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_21155_1	871963.Desdi_0742	3.848e-60	216.0	29HWC@1|root,304TF@2|Bacteria,1VJR2@1239|Firmicutes,24S15@186801|Clostridia,2658U@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
HKD2_k127_21155_0	1034347.CAHJ01000029_gene3543	2.442e-148	499.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,PilZ
HKD2_k127_2129643_4	1347086.CCBA010000023_gene2173	4.147e-31	128.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4084,EAL,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PilZ
HKD2_k127_2129643_1	1403313.AXBR01000008_gene727	1.92e-248	769.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,1ZBXR@1386|Bacillus	91061|Bacilli	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His
HKD2_k127_2129643_0	1403313.AXBR01000008_gene726	3.772e-319	983.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,1ZBXI@1386|Bacillus	91061|Bacilli	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HKD2_k127_2129643_2	1403313.AXBR01000008_gene724	1.242e-148	480.0	COG0624@1|root,COG0624@2|Bacteria,1TPSM@1239|Firmicutes,4HD69@91061|Bacilli,1ZDSF@1386|Bacillus	91061|Bacilli	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD2_k127_2129643_3	1403313.AXBR01000008_gene723	2.404e-142	454.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,4H9KZ@91061|Bacilli,1ZBGG@1386|Bacillus	91061|Bacilli	H	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	yrvM	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
HKD2_k127_2129643_6	1340434.AXVA01000010_gene5484	2.354e-05	48.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2162476_9	1403313.AXBR01000008_gene505	5.064e-36	141.0	2E7KE@1|root,3322G@2|Bacteria,1VG6C@1239|Firmicutes,4HNMG@91061|Bacilli,1ZH76@1386|Bacillus	91061|Bacilli	S	Stage III sporulation protein AF (Spore_III_AF)	spoIIIAF	-	-	ko:K06395	-	-	-	-	ko00000	-	-	-	Spore_III_AF
HKD2_k127_2162476_4	1174504.AJTN02000225_gene1886	2.832e-83	282.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_2162476_7	1403313.AXBR01000008_gene503	3.228e-54	197.0	29WYG@1|root,30IKQ@2|Bacteria,1V4Y2@1239|Firmicutes,4HI5K@91061|Bacilli,1ZHEH@1386|Bacillus	91061|Bacilli	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
HKD2_k127_2162476_6	1403313.AXBR01000008_gene502	1.85e-62	219.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,1ZGFF@1386|Bacillus	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD2_k127_2162476_0	1403313.AXBR01000008_gene501	1.086e-264	818.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1ZC56@1386|Bacillus	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD2_k127_2162476_5	1403313.AXBR01000008_gene500	5.045e-75	253.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,1ZG6N@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yqhY	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD2_k127_2162476_8	1403313.AXBR01000008_gene499	2.216e-53	190.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus	91061|Bacilli	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HKD2_k127_2162476_2	1403313.AXBR01000008_gene498	2.728e-155	494.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HKD2_k127_2162476_1	1174504.AJTN02000042_gene3077	1.275e-205	649.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HKD2_k127_2162476_10	1403313.AXBR01000007_gene495	8.052e-31	123.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,1ZIVS@1386|Bacillus	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HKD2_k127_2162476_3	1403313.AXBR01000007_gene494	7.178e-141	452.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,1ZC4G@1386|Bacillus	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD2_k127_218861_2	1134413.ANNK01000091_gene48	1.441e-130	439.0	COG1719@1|root,COG3835@1|root,COG1719@2|Bacteria,COG3835@2|Bacteria,1TRK4@1239|Firmicutes,4HB2R@91061|Bacilli,1ZCZ8@1386|Bacillus	91061|Bacilli	KT	hydrocarbon binding protein (contains V4R domain)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,V4R,XylR_N
HKD2_k127_218861_1	1045855.DSC_09350	7.025e-144	460.0	COG1028@1|root,COG1028@2|Bacteria,1N32I@1224|Proteobacteria,1RRJG@1236|Gammaproteobacteria,1X5BU@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.56	ko:K08690	ko00621,ko01100,ko01120,ko01220,map00621,map01100,map01120,map01220	M00543	R05239,R05241	RC00534	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
HKD2_k127_218861_4	935836.JAEL01000041_gene4733	1.315e-47	173.0	COG2146@1|root,COG2146@2|Bacteria,1VF0R@1239|Firmicutes,4HSGD@91061|Bacilli	91061|Bacilli	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
HKD2_k127_218861_3	358220.C380_15930	3.766e-85	285.0	COG5517@1|root,COG5517@2|Bacteria,1RDWV@1224|Proteobacteria,2VX4T@28216|Betaproteobacteria,4AI7N@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Ring hydroxylating beta subunit	-	-	1.14.12.11,1.14.12.18,1.14.12.3	ko:K15750,ko:K16268	ko00361,ko00362,ko00621,ko00623,ko00625,ko01100,ko01120,ko01220,map00361,map00362,map00621,map00623,map00625,map01100,map01120,map01220	M00543,M00547	R03543,R03559,R05261,R05262,R05263,R05264,R05429,R06831,R06856,R09151,R09152	RC00098,RC00267,RC00951,RC03011,RC03012,RC03013	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Ring_hydroxyl_B
HKD2_k127_218861_0	358220.C380_15925	3.655e-266	824.0	COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,2VQ87@28216|Betaproteobacteria,4AG7U@80864|Comamonadaceae	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	bphA1	-	1.14.12.11,1.14.12.18,1.14.12.19,1.14.12.3	ko:K03268,ko:K05708,ko:K08689	ko00360,ko00361,ko00362,ko00621,ko00623,ko00625,ko01100,ko01120,ko01220,map00360,map00361,map00362,map00621,map00623,map00625,map01100,map01120,map01220	M00543,M00545,M00547	R03543,R03559,R05261,R05262,R05263,R05264,R05429,R06782,R06783,R06831,R06856,R09151,R09152	RC00098,RC00267,RC00951,RC03011,RC03012,RC03013	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
HKD2_k127_218861_5	768710.DesyoDRAFT_1594	1.231e-10	61.0	COG1309@1|root,COG1309@2|Bacteria,1UWC3@1239|Firmicutes,25MKA@186801|Clostridia,266A8@186807|Peptococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_219697_3	1347369.CCAD010000045_gene528	9.464e-63	220.0	COG1595@1|root,COG1595@2|Bacteria,1UZM5@1239|Firmicutes,4HEK0@91061|Bacilli,1ZEV7@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_219697_0	1347369.CCAD010000045_gene529	7.806e-117	387.0	COG1252@1|root,COG1252@2|Bacteria,1UY7H@1239|Firmicutes,4HF9C@91061|Bacilli,1ZMS6@1386|Bacillus	91061|Bacilli	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD2_k127_219697_4	1052684.PPM_4100	1.988e-45	167.0	COG4994@1|root,COG4994@2|Bacteria,1VN9J@1239|Firmicutes,4HZ1D@91061|Bacilli,272R3@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD2_k127_219697_2	720555.BATR1942_11930	2.667e-74	252.0	COG0454@1|root,COG0454@2|Bacteria,1V4EA@1239|Firmicutes,4HHBF@91061|Bacilli,1ZGG7@1386|Bacillus	91061|Bacilli	K	acetyltransferase	ysnE	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD2_k127_219697_1	1461580.CCAS010000086_gene4351	1.121e-96	318.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,1ZEC8@1386|Bacillus	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HKD2_k127_2221578_3	1403313.AXBR01000024_gene4664	3.579e-26	109.0	COG2427@1|root,32RCT@2|Bacteria,1V7FZ@1239|Firmicutes,4HK07@91061|Bacilli,1ZR46@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1641)	yjlC	-	-	-	-	-	-	-	-	-	-	-	DUF1641
HKD2_k127_2221578_4	935836.JAEL01000076_gene3059	2.052e-12	70.0	29RVN@1|root,30CZP@2|Bacteria,1UAM5@1239|Firmicutes,4IKZU@91061|Bacilli,1ZII6@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2221578_1	1243664.CAVL020000008_gene4275	1.069e-90	305.0	COG0515@1|root,COG0515@2|Bacteria,1V52K@1239|Firmicutes,4IQ8M@91061|Bacilli,1ZRK1@1386|Bacillus	91061|Bacilli	KLT	RIO1 family	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HKD2_k127_2221578_0	665959.HMPREF1013_02865	4.876e-107	356.0	29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus	91061|Bacilli	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
HKD2_k127_2221578_2	1403313.AXBR01000013_gene1348	6.701e-84	279.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus	91061|Bacilli	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD2_k127_2223980_12	1385514.N782_03495	6.097e-06	50.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2223980_11	1385514.N782_03495	9.868e-07	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2223980_5	1403313.AXBR01000013_gene1494	1e-84	283.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,4HH9K@91061|Bacilli,1ZFM5@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	alaR	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HKD2_k127_2223980_2	1403313.AXBR01000013_gene1495	1.119e-207	650.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus	91061|Bacilli	E	Aminotransferase	yugH	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_2223980_6	1174504.AJTN02000200_gene3507	1.465e-62	217.0	COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,1ZHK5@1386|Bacillus	91061|Bacilli	J	RNA binding protein (contains ribosomal protein S1 domain)	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
HKD2_k127_2223980_1	935836.JAEL01000021_gene1547	3.929e-217	677.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,1ZAV3@1386|Bacillus	91061|Bacilli	E	Catalyzes the interconversion of ornithine to glutamate semialdehyde	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
HKD2_k127_2223980_8	218284.CCDN010000005_gene3475	8.791e-36	137.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,4HP56@91061|Bacilli,1ZHUV@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF378)	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
HKD2_k127_2223980_3	1403313.AXBR01000013_gene1500	1.676e-202	634.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,1ZBKF@1386|Bacillus	91061|Bacilli	C	oxidoreductases, Fe-dependent alcohol dehydrogenase family	yugJ	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
HKD2_k127_2223980_0	1403313.AXBR01000013_gene1501	3.75e-255	791.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,1ZB6B@1386|Bacillus	91061|Bacilli	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD2_k127_2223980_4	720555.BATR1942_01025	1.692e-134	430.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,1ZBN0@1386|Bacillus	91061|Bacilli	K	transcriptional regulatory protein	yeeN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HKD2_k127_2223980_9	398511.BpOF4_09460	3.204e-21	97.0	2EE98@1|root,3383N@2|Bacteria,1VGWV@1239|Firmicutes,4HQJB@91061|Bacilli,1ZG7F@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF5082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5082
HKD2_k127_2223980_10	1121091.AUMP01000030_gene3999	5.129e-16	80.0	2ETT8@1|root,33MAM@2|Bacteria,1VM27@1239|Firmicutes,4HSSA@91061|Bacilli	91061|Bacilli	S	Family of unknown function (DUF5344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5344
HKD2_k127_2223980_7	1002809.SSIL_1312	4.186e-53	205.0	COG5444@1|root,COG5444@2|Bacteria,1TXMN@1239|Firmicutes,4IIPK@91061|Bacilli,26H15@186818|Planococcaceae	2|Bacteria	S	nuclease activity	-	-	-	ko:K21493	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	LXG,Ntox15
HKD2_k127_2231879_3	1403313.AXBR01000021_gene3174	3.397e-15	75.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZBC0@1386|Bacillus	91061|Bacilli	M	stage V sporulation protein D	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD2_k127_2231879_0	1403313.AXBR01000021_gene3173	8.952e-251	781.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD2_k127_2231879_2	1403313.AXBR01000021_gene3172	1.184e-180	568.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,1ZBIK@1386|Bacillus	91061|Bacilli	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HKD2_k127_2231879_1	1403313.AXBR01000021_gene3171	4.03e-243	756.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD2_k127_2239958_0	1403313.AXBR01000013_gene1327	1.688e-260	810.0	COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yvcD	-	-	-	-	-	-	-	-	-	-	-	HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8
HKD2_k127_2239958_2	714961.BFZC1_09280	1.851e-179	565.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3IW96@400634|Lysinibacillus	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD2_k127_2239958_6	1403313.AXBR01000013_gene1329	3.051e-92	304.0	COG1051@1|root,COG1051@2|Bacteria,1V3BX@1239|Firmicutes,4HGE6@91061|Bacilli,1ZFT4@1386|Bacillus	91061|Bacilli	F	Nudix hydrolase	yvcI	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD2_k127_2239958_4	1174504.AJTN02000230_gene1234	4.943e-156	496.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,1ZCWE@1386|Bacillus	91061|Bacilli	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HKD2_k127_2239958_3	1403313.AXBR01000013_gene1331	7.919e-174	550.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,1ZB2R@1386|Bacillus	91061|Bacilli	S	Required for morphogenesis under gluconeogenic growth conditions	yvcK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
HKD2_k127_2239958_1	1403313.AXBR01000013_gene1332	5.546e-183	574.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus	91061|Bacilli	K	May be required for sporulation	whiA	GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
HKD2_k127_2239958_7	1403313.AXBR01000013_gene1333	1.136e-32	129.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKKW@91061|Bacilli,1ZHV0@1386|Bacillus	91061|Bacilli	G	Phosphocarrier protein Chr	crh	-	-	ko:K11184	-	-	-	-	ko00000	-	-	-	PTS-HPr
HKD2_k127_2239958_5	1403313.AXBR01000013_gene1334	5.284e-109	355.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,1ZARS@1386|Bacillus	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD2_k127_2282179_4	1384049.CD29_02740	1.869e-33	131.0	2EEHB@1|root,338B5@2|Bacteria,1VHMZ@1239|Firmicutes,4HPTA@91061|Bacilli,3IYEP@400634|Lysinibacillus	91061|Bacilli	S	Cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HKD2_k127_2282179_2	649747.HMPREF0083_04490	4.518e-87	290.0	COG2318@1|root,COG2318@2|Bacteria,1V70V@1239|Firmicutes,4HJAI@91061|Bacilli,270JZ@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD2_k127_2282179_1	1461580.CCAS010000086_gene4350	1.166e-87	291.0	COG3773@1|root,COG3773@2|Bacteria,1V1K8@1239|Firmicutes,4HFTU@91061|Bacilli,1ZFVT@1386|Bacillus	91061|Bacilli	M	Cell wall	cwlJ	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
HKD2_k127_2282179_3	1294265.JCM21738_1549	2.084e-85	285.0	COG0782@1|root,COG0782@2|Bacteria	2|Bacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD2_k127_2282179_0	1078085.HMPREF1210_00693	1.158e-127	412.0	2EUS4@1|root,33N7Q@2|Bacteria,1VKV1@1239|Firmicutes,4HRK2@91061|Bacilli	91061|Bacilli	S	Toxin SpoIISA, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	SpoIISA_toxin
HKD2_k127_2284933_1	1403313.AXBR01000006_gene96	2.207e-105	349.0	COG2755@1|root,COG2755@2|Bacteria,1UZYP@1239|Firmicutes,4HDQY@91061|Bacilli,1ZEFB@1386|Bacillus	91061|Bacilli	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_2284933_3	1403313.AXBR01000006_gene95	9.27e-76	258.0	COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,1ZF26@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ypmS	-	-	-	-	-	-	-	-	-	-	-	DUF2140
HKD2_k127_2284933_2	1340434.AXVA01000016_gene770	1.127e-89	297.0	COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,1ZCC5@1386|Bacillus	91061|Bacilli	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HKD2_k127_2284933_4	1403313.AXBR01000006_gene92	3.526e-75	255.0	COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,1ZFQG@1386|Bacillus	91061|Bacilli	O	peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
HKD2_k127_2284933_0	1403313.AXBR01000006_gene88	1.099e-164	524.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HB1P@91061|Bacilli,1ZQ9Y@1386|Bacillus	91061|Bacilli	V	peptidase S66	yocD	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD2_k127_2286802_3	1174504.AJTN02000219_gene1049	4.183e-33	129.0	COG3541@1|root,COG3541@2|Bacteria,1TT57@1239|Firmicutes,4HD38@91061|Bacilli,1ZBMK@1386|Bacillus	91061|Bacilli	S	Predicted nucleotidyltransferase	ycgL	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
HKD2_k127_2286802_5	1236973.JCM9157_4762	2.958e-11	64.0	2BGZF@1|root,32AZJ@2|Bacteria,1UB2A@1239|Firmicutes,4IMF6@91061|Bacilli,1ZK0N@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2286802_6	1145276.T479_17270	8.741e-06	49.0	2F7Z6@1|root,33DE9@2|Bacteria,1VKF9@1239|Firmicutes,4HS2A@91061|Bacilli,3J01H@400634|Lysinibacillus	91061|Bacilli	S	YfhD-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YfhD
HKD2_k127_2286802_1	649639.Bcell_4031	1.459e-91	304.0	COG1670@1|root,COG1670@2|Bacteria,1V5BA@1239|Firmicutes,4HHR5@91061|Bacilli,1ZG8F@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD2_k127_2286802_0	1033734.CAET01000005_gene3698	1.914e-94	316.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,1ZCUB@1386|Bacillus	91061|Bacilli	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
HKD2_k127_2286802_2	1123252.ATZF01000004_gene2234	2.341e-91	301.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HKD2_k127_2286802_4	290402.Cbei_4071	2.707e-30	123.0	COG1971@1|root,COG1971@2|Bacteria,1VBB9@1239|Firmicutes,25CUU@186801|Clostridia,36M3E@31979|Clostridiaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD2_k127_2287068_1	1403313.AXBR01000025_gene4870	5.231e-168	532.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus	91061|Bacilli	S	COG1253 Hemolysins and related proteins containing CBS domains	yhdP	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD2_k127_2287068_2	1174504.AJTN02000059_gene4481	1.248e-63	222.0	2AKA0@1|root,31B0I@2|Bacteria,1V6KC@1239|Firmicutes,4HK0A@91061|Bacilli,1ZH2N@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
HKD2_k127_2287068_4	1174504.AJTN02000059_gene4481	3.427e-46	171.0	2AKA0@1|root,31B0I@2|Bacteria,1V6KC@1239|Firmicutes,4HK0A@91061|Bacilli,1ZH2N@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
HKD2_k127_2287068_3	1174504.AJTN02000050_gene1743	1.457e-46	173.0	COG1846@1|root,COG1846@2|Bacteria,1V8TC@1239|Firmicutes,4HK9G@91061|Bacilli,1ZBA1@1386|Bacillus	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	ycgE	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
HKD2_k127_2287068_0	1403313.AXBR01000025_gene4877	1.378e-245	767.0	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	mdr	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_2291951_4	1117379.BABA_22688	1.601e-19	91.0	29RKP@1|root,30CPX@2|Bacteria,1UA6Y@1239|Firmicutes,4IKI3@91061|Bacilli,1ZH1M@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2291951_1	1461580.CCAS010000044_gene3402	3.65e-83	283.0	2E161@1|root,32WKW@2|Bacteria,1VCRY@1239|Firmicutes,4HM23@91061|Bacilli,1ZF5P@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2291951_3	1131730.BAVI_03529	2.584e-54	194.0	2ECB2@1|root,3369D@2|Bacteria,1VHPV@1239|Firmicutes,4HP90@91061|Bacilli,1ZGD5@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2291951_2	1461580.CCAS010000044_gene3400	1.906e-76	259.0	COG0681@1|root,COG0681@2|Bacteria,1VJEA@1239|Firmicutes,4HPIS@91061|Bacilli,1ZI08@1386|Bacillus	91061|Bacilli	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD2_k127_2291951_0	665952.HMPREF1015_01747	1.872e-131	425.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,1ZBT5@1386|Bacillus	91061|Bacilli	K	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD2_k127_2315495_2	1117379.BABA_11501	1.154e-175	557.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,1ZB5A@1386|Bacillus	91061|Bacilli	S	COG4956 Integral membrane protein (PIN domain superfamily)	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TRAM
HKD2_k127_2315495_7	1174504.AJTN02000017_gene203	1.215e-103	341.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
HKD2_k127_2315495_9	1403313.AXBR01000025_gene5003	9.426e-88	291.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,1ZB1U@1386|Bacillus	91061|Bacilli	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
HKD2_k127_2315495_16	1385514.N782_03495	5.694e-10	61.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2315495_0	1403313.AXBR01000025_gene5002	1.84e-280	865.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,1ZAWK@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065	6.1.1.24	ko:K09698	ko00970,ko01100,map00970,map01100	M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSB619.SA_RS02860	tRNA-synt_1c
HKD2_k127_2315495_6	1034347.CAHJ01000085_gene1588	2.8e-117	379.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,1ZCNM@1386|Bacillus	91061|Bacilli	E	Serine acetyltransferase	cysE	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02865,iYO844.BSU00930	Hexapep,SATase_N
HKD2_k127_2315495_1	1174504.AJTN02000017_gene207	1.153e-258	802.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,1ZB69@1386|Bacillus	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HKD2_k127_2315495_13	1403313.AXBR01000025_gene4998	3.595e-65	224.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,1ZH0Z@1386|Bacillus	91061|Bacilli	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
HKD2_k127_2315495_3	1403313.AXBR01000025_gene4997	8.145e-138	440.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD2_k127_2315495_10	1403313.AXBR01000025_gene4996	9.12e-86	286.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,1ZCMG@1386|Bacillus	91061|Bacilli	S	RNA-binding protein containing a PIN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
HKD2_k127_2315495_5	1174504.AJTN02000017_gene211	1.897e-121	391.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,1ZBEV@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_2315495_15	796606.BMMGA3_00615	2.523e-16	79.0	COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,1ZKEU@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD2_k127_2315495_14	1403313.AXBR01000025_gene4994	1.124e-25	107.0	COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,1ZIY2@1386|Bacillus	91061|Bacilli	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HKD2_k127_2315495_8	1174504.AJTN02000017_gene213	7.451e-102	332.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,1ZBRH@1386|Bacillus	91061|Bacilli	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HKD2_k127_2315495_11	796606.BMMGA3_00630	7.687e-84	281.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,1ZFIG@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HKD2_k127_2315495_4	1403313.AXBR01000025_gene4991	1.828e-132	424.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HKD2_k127_2315495_12	1174504.AJTN02000017_gene216	6.719e-81	271.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HKD2_k127_2335861_1	1131730.BAVI_25140	9.881e-80	269.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HDYW@91061|Bacilli,1ZC45@1386|Bacillus	91061|Bacilli	M	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	ykoN	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD2_k127_2335861_2	666686.B1NLA3E_13485	6.312e-62	214.0	COG3339@1|root,COG3339@2|Bacteria,1VAM6@1239|Firmicutes,4HKE7@91061|Bacilli,1ZH5S@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HKD2_k127_2335861_0	666686.B1NLA3E_08985	1.176e-169	535.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5,Fer4_7,Fer4_9
HKD2_k127_243776_16	1469948.JPNB01000001_gene1204	4.433e-06	51.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,36GH1@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD2_k127_243776_17	1123489.AUAN01000011_gene1480	1.872e-05	47.0	COG3677@1|root,COG3677@2|Bacteria,1V39M@1239|Firmicutes	1239|Firmicutes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
HKD2_k127_243776_10	1174504.AJTN02000099_gene2595	2.499e-22	102.0	2DJG3@1|root,30609@2|Bacteria,1TYZ9@1239|Firmicutes,4I85K@91061|Bacilli,1ZP3K@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_243776_2	1174504.AJTN02000157_gene515	2.03e-179	569.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,1ZDCS@1386|Bacillus	91061|Bacilli	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	yknZ	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD2_k127_243776_9	441769.ABFU01000053_gene4090	4.03e-30	120.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,1ZC14@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	yknY	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_243776_6	1034347.CAHJ01000022_gene3320	1.285e-61	215.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,1ZC14@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	yknY	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_243776_4	1131730.BAVI_07269	1.815e-112	376.0	COG0845@1|root,COG0845@2|Bacteria,1VBR9@1239|Firmicutes,4HG5X@91061|Bacilli,1ZQX8@1386|Bacillus	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
HKD2_k127_243776_8	1243664.CAVL020000008_gene4380	9.393e-53	194.0	2EJ6V@1|root,33CY2@2|Bacteria,1VPDN@1239|Firmicutes,4HS8D@91061|Bacilli,1ZIQW@1386|Bacillus	91061|Bacilli	S	Yip1 domain	yknW	-	-	-	-	-	-	-	-	-	-	-	Yip1
HKD2_k127_243776_3	666686.B1NLA3E_08360	8.873e-173	549.0	COG4362@1|root,COG4362@2|Bacteria,1TRDM@1239|Firmicutes,4HAR0@91061|Bacilli,1ZB33@1386|Bacillus	91061|Bacilli	C	Belongs to the NOS family. Bacterial NOS oxygenase subfamily	nos	GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004517,GO:0006807,GO:0006809,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017144,GO:0034641,GO:0042133,GO:0042136,GO:0044237,GO:0044249,GO:0044271,GO:0046209,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:1903409,GO:2001057	1.14.14.47	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	-	R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000	-	-	-	NO_synthase
HKD2_k127_243776_7	666686.B1NLA3E_16895	9.077e-54	193.0	COG2963@1|root,COG2963@2|Bacteria,1V771@1239|Firmicutes,4HJ16@91061|Bacilli,1ZH8P@1386|Bacillus	91061|Bacilli	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_243776_11	318464.IO99_18810	1.033e-18	87.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,24B89@186801|Clostridia,36GS0@31979|Clostridiaceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
HKD2_k127_243776_5	1403313.AXBR01000007_gene215	6.288e-68	233.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli,1ZC3V@1386|Bacillus	91061|Bacilli	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
HKD2_k127_243776_13	218284.CCDN010000001_gene816	2.403e-08	55.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,1ZDA0@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HKD2_k127_243776_1	1403313.AXBR01000021_gene3012	6.774e-311	962.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus	91061|Bacilli	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HKD2_k127_243776_0	1403313.AXBR01000021_gene3013	0.0	1398.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus	91061|Bacilli	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HKD2_k127_252147_0	218284.CCDN010000008_gene4076	2.964e-136	447.0	COG3307@1|root,COG3307@2|Bacteria,1U9JD@1239|Firmicutes,4IJQJ@91061|Bacilli,1ZDN2@1386|Bacillus	91061|Bacilli	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_252147_2	218284.CCDN010000008_gene4075	1.28e-21	99.0	29S18@1|root,30D5M@2|Bacteria,1UAVT@1239|Firmicutes,4IM8N@91061|Bacilli,1ZJGY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2572412_5	1121090.KB894685_gene3937	2.634e-22	99.0	COG0639@1|root,COG0639@2|Bacteria,1TPCI@1239|Firmicutes,4HBD8@91061|Bacilli,1ZBK8@1386|Bacillus	91061|Bacilli	T	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP	prpE	GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.16,3.6.1.41	ko:K01090,ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD2_k127_2572412_0	1340434.AXVA01000003_gene1454	8.863e-136	435.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus	91061|Bacilli	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD2_k127_2572412_4	1121929.KB898672_gene4013	9.987e-38	148.0	28Q17@1|root,2ZCJP@2|Bacteria,1V1H6@1239|Firmicutes,4HGUD@91061|Bacilli,470RX@74385|Gracilibacillus	91061|Bacilli	S	Spore coat protein Z	-	-	-	ko:K06344	-	-	-	-	ko00000	-	-	-	Spore-coat_CotZ
HKD2_k127_2572412_2	1294265.JCM21738_1905	6.415e-45	165.0	2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli,1ZHZZ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1360)	yjcA	-	-	-	-	-	-	-	-	-	-	-	DUF1360
HKD2_k127_2572412_3	997296.PB1_02765	1.54e-40	154.0	2CY4V@1|root,32T3F@2|Bacteria,1VDQ0@1239|Firmicutes,4HKEQ@91061|Bacilli,1ZIB4@1386|Bacillus	91061|Bacilli	S	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YhcN_YlaJ
HKD2_k127_2572412_1	1340434.AXVA01000003_gene1459	1.111e-82	276.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,4HH0C@91061|Bacilli,1ZFW2@1386|Bacillus	91061|Bacilli	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HKD2_k127_25822_8	1145276.T479_03725	3.689e-23	99.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,3IYC3@400634|Lysinibacillus	91061|Bacilli	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_25822_1	1243664.CAVL020000049_gene5077	1.007e-143	461.0	COG0715@1|root,COG0715@2|Bacteria,1TRT8@1239|Firmicutes,4HCK6@91061|Bacilli,1ZB5K@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
HKD2_k127_25822_2	1243664.CAVL020000049_gene5076	2.913e-118	384.0	COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HCJ7@91061|Bacilli,1ZBH6@1386|Bacillus	91061|Bacilli	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD2_k127_25822_6	997296.PB1_11569	1.446e-66	231.0	COG1733@1|root,COG1733@2|Bacteria,1V622@1239|Firmicutes,4HH7F@91061|Bacilli,1ZGF8@1386|Bacillus	91061|Bacilli	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD2_k127_25822_4	796606.BMMGA3_08575	4.793e-79	268.0	297NE@1|root,2ZUVC@2|Bacteria,1V58Z@1239|Firmicutes,4HI1Z@91061|Bacilli,1ZFX0@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
HKD2_k127_25822_0	796606.BMMGA3_08570	1.245e-144	466.0	COG1960@1|root,COG1960@2|Bacteria,1UYHK@1239|Firmicutes,4HCT5@91061|Bacilli,1ZDKG@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_N
HKD2_k127_25822_3	649747.HMPREF0083_00153	8.428e-83	278.0	COG3226@1|root,COG3226@2|Bacteria,1V50H@1239|Firmicutes,4HJQ2@91061|Bacilli,26WQ2@186822|Paenibacillaceae	91061|Bacilli	K	TetR family transcriptional regulator	pksA	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
HKD2_k127_25822_5	720555.BATR1942_06340	8.964e-78	264.0	28NRE@1|root,2ZBQP@2|Bacteria,1V2C0@1239|Firmicutes,4HGF6@91061|Bacilli,1ZFQD@1386|Bacillus	91061|Bacilli	S	Membrane	ymcC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_25822_7	1403313.AXBR01000007_gene446	5.045e-63	218.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus	91061|Bacilli	S	COG1073 Hydrolases of the alpha beta superfamily	yqkD	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD2_k127_2599609_0	1408303.JNJJ01000057_gene1323	0.0	1064.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus	91061|Bacilli	P	P-type ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD2_k127_2599609_3	997296.PB1_12419	2.682e-31	123.0	COG2608@1|root,COG2608@2|Bacteria,1VERB@1239|Firmicutes,4HNP0@91061|Bacilli,1ZITG@1386|Bacillus	91061|Bacilli	P	Copper resistance protein CopZ	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
HKD2_k127_2599609_2	997296.PB1_12424	6.684e-51	182.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,4HJ3J@91061|Bacilli,1ZH3J@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	csoR_2	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HKD2_k127_2599609_1	574375.BAGA_28945	4.56e-307	950.0	COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,1ZC7Q@1386|Bacillus	91061|Bacilli	E	amino acid	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD2_k127_266608_3	1403313.AXBR01000009_gene796	2.214e-250	775.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD2_k127_266608_4	1403313.AXBR01000009_gene797	7.129e-232	722.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
HKD2_k127_266608_8	1403313.AXBR01000009_gene798	1.762e-116	384.0	COG3118@1|root,COG3118@2|Bacteria,1VEXG@1239|Firmicutes,4HQMC@91061|Bacilli,1ZDM8@1386|Bacillus	91061|Bacilli	O	COG0457 FOG TPR repeat	ysoA	-	-	-	-	-	-	-	-	-	-	-	TPR_19
HKD2_k127_266608_10	1174504.AJTN02000191_gene4221	1.117e-98	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,1ZAVC@1386|Bacillus	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HKD2_k127_266608_2	1403313.AXBR01000009_gene800	5.129e-275	849.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10700	Aconitase
HKD2_k127_266608_6	1403313.AXBR01000009_gene801	1.208e-185	585.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli,1ZB3Y@1386|Bacillus	91061|Bacilli	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU28270	Iso_dh
HKD2_k127_266608_1	1403313.AXBR01000009_gene802	2.732e-277	858.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus	91061|Bacilli	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10690,iYO844.BSU28280	HMGL-like,LeuA_dimer
HKD2_k127_266608_5	1403313.AXBR01000009_gene803	4.826e-192	602.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli,1ZCH5@1386|Bacillus	91061|Bacilli	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
HKD2_k127_266608_11	1403313.AXBR01000009_gene804	5.239e-79	267.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli,1ZFP3@1386|Bacillus	91061|Bacilli	E	Acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ACT,ACT_5,ALS_ss_C
HKD2_k127_266608_0	1174504.AJTN02000191_gene4227	3.622e-279	867.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,1ZB1D@1386|Bacillus	91061|Bacilli	E	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	iYO844.BSU28310	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD2_k127_266608_7	1123405.AUMM01000063_gene1669	1.293e-157	501.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli,26PIU@186821|Sporolactobacillaceae	91061|Bacilli	H	N-terminal domain of lipoyl synthase of Radical_SAM family	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HKD2_k127_266608_9	1385511.N783_04185	8.612e-113	369.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,2Y9K9@289201|Pontibacillus	91061|Bacilli	H	Octanoyltransferase	lipM	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HKD2_k127_266608_12	1174504.AJTN02000191_gene4229	4.643e-54	193.0	COG1876@1|root,COG1876@2|Bacteria,1VC9C@1239|Firmicutes,4HNA4@91061|Bacilli,1ZGE1@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_4
HKD2_k127_2671191_0	1117379.BABA_19971	4.046e-137	440.0	COG3384@1|root,COG3384@2|Bacteria,1TSRZ@1239|Firmicutes,4HAAN@91061|Bacilli,1ZBC3@1386|Bacillus	91061|Bacilli	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	ligB1	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
HKD2_k127_2671191_1	1340434.AXVA01000008_gene3728	1.286e-86	289.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V2FR@1239|Firmicutes,4HGV3@91061|Bacilli,1ZCQZ@1386|Bacillus	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	puuR_1	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
HKD2_k127_2671191_2	195250.CM001776_gene1002	1.24e-12	75.0	COG0593@1|root,COG0593@2|Bacteria,1G1BW@1117|Cyanobacteria,1GYYD@1129|Synechococcus	1117|Cyanobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD2_k127_2671191_3	218284.CCDN010000002_gene2425	9.855e-10	60.0	2EECF@1|root,3386Q@2|Bacteria,1VIE5@1239|Firmicutes,4HPWH@91061|Bacilli,1ZI7F@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3949)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3949
HKD2_k127_272612_1	574376.BAMA_23000	6.242e-87	290.0	COG1451@1|root,COG1451@2|Bacteria,1V0CS@1239|Firmicutes,4HE0S@91061|Bacilli,1ZBQ8@1386|Bacillus	91061|Bacilli	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
HKD2_k127_272612_2	1347369.CCAD010000075_gene3210	7.168e-80	269.0	COG4807@1|root,COG4807@2|Bacteria,1V4DA@1239|Firmicutes,4HH2A@91061|Bacilli,1ZFS1@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1456)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
HKD2_k127_272612_0	717606.PaecuDRAFT_1786	8.584e-95	319.0	COG0491@1|root,COG0491@2|Bacteria,1UUWQ@1239|Firmicutes,4HFZ8@91061|Bacilli,27532@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HKD2_k127_272612_3	218284.CCDN010000002_gene2658	9.219e-19	85.0	COG2318@1|root,COG2318@2|Bacteria,1V38X@1239|Firmicutes,4HGQ4@91061|Bacilli,1ZHN6@1386|Bacillus	91061|Bacilli	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
HKD2_k127_2765680_2	666686.B1NLA3E_20175	1.28e-59	209.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ywkD	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD2_k127_2765680_4	235909.GK3232	0.0004293	44.0	29HWF@1|root,304TI@2|Bacteria,1TX55@1239|Firmicutes,4I61F@91061|Bacilli,1WH3E@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2765680_1	1307436.PBF_01435	5.734e-167	535.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA
HKD2_k127_2765680_0	1117379.BABA_06426	1.868e-179	566.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,1ZB5V@1386|Bacillus	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD2_k127_2765680_3	1243664.CAVL020000058_gene4458	3.084e-53	191.0	COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,4H9XA@91061|Bacilli,1ZBXX@1386|Bacillus	91061|Bacilli	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
HKD2_k127_2804044_1	1273538.G159_02485	4.367e-60	213.0	COG1309@1|root,COG1309@2|Bacteria,1V1C8@1239|Firmicutes,4HJ6G@91061|Bacilli,26FNU@186818|Planococcaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
HKD2_k127_2804044_0	649747.HMPREF0083_04931	3.374e-169	536.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,26RP3@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	mmgA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
HKD2_k127_2832212_6	1403313.AXBR01000009_gene868	1.404e-85	286.0	COG0398@1|root,COG0398@2|Bacteria,1V8XH@1239|Firmicutes,4HJZ2@91061|Bacilli,1ZFKY@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD2_k127_2832212_9	1174504.AJTN02000191_gene4279	4.908e-25	107.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,4HNXQ@91061|Bacilli,1ZIYS@1386|Bacillus	91061|Bacilli	S	Membrane	ysdA	-	-	-	-	-	-	-	-	-	-	-	DUF1294
HKD2_k127_2832212_7	1403313.AXBR01000009_gene870	3.942e-65	223.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,1ZG75@1386|Bacillus	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD2_k127_2832212_8	1423321.AS29_16230	7.405e-28	114.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,1ZJBX@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HKD2_k127_2832212_3	1211814.CAPG01000051_gene2660	7.268e-95	314.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,1ZCBZ@1386|Bacillus	91061|Bacilli	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HKD2_k127_2832212_0	1403313.AXBR01000009_gene876	0.0	1208.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HKD2_k127_2832212_4	1403313.AXBR01000009_gene877	1.554e-91	309.0	2AZZM@1|root,31S9P@2|Bacteria,1V6WH@1239|Firmicutes,4HMZM@91061|Bacilli,1ZDWA@1386|Bacillus	91061|Bacilli	S	YtxC-like family	ytxC	-	-	-	-	-	-	-	-	-	-	-	YtxC
HKD2_k127_2832212_2	1403313.AXBR01000009_gene878	2.931e-147	471.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,1ZB6G@1386|Bacillus	91061|Bacilli	L	Primosomal protein DnaI	dnaI	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	DnaI_N,IstB_IS21
HKD2_k127_2832212_1	1174504.AJTN02000041_gene2441	3.404e-181	578.0	COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,1ZBJY@1386|Bacillus	91061|Bacilli	L	Membrane attachment protein	dnaB	-	-	ko:K03346	-	-	-	-	ko00000,ko03032	-	-	-	DnaB_2
HKD2_k127_2832212_5	1403313.AXBR01000009_gene881	7.683e-87	287.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,1ZFS0@1386|Bacillus	91061|Bacilli	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HKD2_k127_2838586_4	1403313.AXBR01000021_gene2979	1.248e-145	464.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus	91061|Bacilli	P	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
HKD2_k127_2838586_0	1403313.AXBR01000021_gene2980	3.514e-204	642.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus	91061|Bacilli	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD2_k127_2838586_2	1403313.AXBR01000021_gene2982	1.039e-163	519.0	COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZBII@1386|Bacillus	91061|Bacilli	O	stage V sporulation protein K	spoVK	-	-	ko:K06413	-	-	-	-	ko00000	-	-	-	AAA
HKD2_k127_2838586_8	1174504.AJTN02000023_gene4674	1.33e-37	143.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4HKN1@91061|Bacilli,1ZQS1@1386|Bacillus	91061|Bacilli	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
HKD2_k127_2838586_3	1403313.AXBR01000021_gene2984	2.639e-156	497.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HKD2_k127_2838586_7	1340434.AXVA01000006_gene4395	1.008e-56	205.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD2_k127_2838586_5	1403313.AXBR01000017_gene3608	1.911e-142	464.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus	91061|Bacilli	T	Histidine kinase	kinB	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA
HKD2_k127_2838586_6	1169144.KB910931_gene988	3.555e-74	253.0	2CJF8@1|root,2ZCAP@2|Bacteria,1V3BA@1239|Firmicutes,4HFSQ@91061|Bacilli,1ZG4X@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3189
HKD2_k127_2838586_1	1211814.CAPG01000048_gene2544	1.441e-190	611.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	tlpA3	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
HKD2_k127_2838586_9	1340434.AXVA01000010_gene5484	5.438e-09	59.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2842675_0	1403313.AXBR01000009_gene830	1.5e-323	992.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05640	FAD_binding_2,Succ_DH_flav_C
HKD2_k127_2842675_1	1403313.AXBR01000009_gene829	1.975e-159	504.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,1ZAPQ@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhB	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
HKD2_k127_2842675_2	1307436.PBF_13084	2.068e-57	202.0	COG0824@1|root,COG0824@2|Bacteria,1V6GS@1239|Firmicutes,4HJ05@91061|Bacilli,1ZH3F@1386|Bacillus	91061|Bacilli	S	thioesterase	ysmA	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD2_k127_2842675_5	1403313.AXBR01000009_gene827	8.898e-24	100.0	COG2197@1|root,COG2197@2|Bacteria,1VBZR@1239|Firmicutes,4HKT4@91061|Bacilli,1ZHTA@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	gerE	-	-	ko:K01994	-	-	-	-	ko00000,ko03000	-	-	-	GerE
HKD2_k127_2842675_3	313595.P700755_002015	3.658e-37	151.0	2DI6B@1|root,3025A@2|Bacteria,4NP85@976|Bacteroidetes,1IIGC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2842675_4	1120965.AUBV01000009_gene3131	1.845e-31	133.0	28MQ6@1|root,2ZAZ6@2|Bacteria,4NJIV@976|Bacteroidetes	976|Bacteroidetes	S	Beta protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_protein
HKD2_k127_288682_1	1499680.CCFE01000011_gene654	5.603e-162	529.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	gmr	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_4,PAS_8,PAS_9
HKD2_k127_288682_3	935837.JAEK01000004_gene4646	4.315e-17	81.0	2DR71@1|root,33AGR@2|Bacteria,1VKHI@1239|Firmicutes,4IMK8@91061|Bacilli,1ZKBW@1386|Bacillus	91061|Bacilli	S	Putative motility protein	yjfB	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
HKD2_k127_288682_2	545693.BMQ_1577	1.904e-103	341.0	COG0428@1|root,COG0428@2|Bacteria,1V1UC@1239|Firmicutes,4HGST@91061|Bacilli,1ZCIQ@1386|Bacillus	91061|Bacilli	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HKD2_k127_288682_4	491915.Aflv_0307	4.708e-13	69.0	2DRT6@1|root,33CYC@2|Bacteria,1VMWG@1239|Firmicutes,4HR9A@91061|Bacilli,21XAN@150247|Anoxybacillus	91061|Bacilli	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
HKD2_k127_288682_0	1380408.AVGH01000029_gene76	7.48e-288	897.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,21W1M@150247|Anoxybacillus	91061|Bacilli	P	Ferrous iron transport protein B C terminus	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	iSB619.SA_RS13395	FeoB_C,FeoB_N,Gate
HKD2_k127_288682_5	1117379.BABA_06006	1.275e-05	47.0	COG1918@1|root,COG1918@2|Bacteria,1VGV9@1239|Firmicutes,4HPQB@91061|Bacilli,1ZJ0N@1386|Bacillus	91061|Bacilli	P	COG1918 Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HKD2_k127_289440_0	1403313.AXBR01000002_gene4425	1.777e-163	521.0	COG2733@1|root,COG2733@2|Bacteria,1TS8F@1239|Firmicutes,4HC8U@91061|Bacilli,1ZCND@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD2_k127_289440_1	1403313.AXBR01000024_gene4605	1.474e-53	189.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKGZ@91061|Bacilli,1ZR2S@1386|Bacillus	91061|Bacilli	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD2_k127_289440_2	1403313.AXBR01000024_gene4606	7.984e-28	113.0	2EISG@1|root,33CHT@2|Bacteria,1VMS2@1239|Firmicutes,4HSBQ@91061|Bacilli,1ZJ70@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2932265_45	1297581.H919_02157	6.646e-14	73.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,21VG8@150247|Anoxybacillus	91061|Bacilli	S	Cytidylyltransferase family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
HKD2_k127_2932265_16	1403313.AXBR01000021_gene3069	1.43e-132	426.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,1ZC2T@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD2_k127_2932265_24	1403313.AXBR01000021_gene3070	5.945e-95	313.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,1ZAZF@1386|Bacillus	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD2_k127_2932265_13	1403313.AXBR01000021_gene3071	4.597e-142	452.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus	91061|Bacilli	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
HKD2_k127_2932265_8	1403313.AXBR01000021_gene3072	4.468e-155	493.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,1ZB7R@1386|Bacillus	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD2_k127_2932265_9	1403313.AXBR01000021_gene3073	6.999e-152	481.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,1ZAYU@1386|Bacillus	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HKD2_k127_2932265_44	1211814.CAPG01000037_gene2075	1.215e-15	86.0	2D5MU@1|root,32TJF@2|Bacteria,1V9ZA@1239|Firmicutes,4HMQI@91061|Bacilli,1ZFEI@1386|Bacillus	91061|Bacilli	-	-	ylxL	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2932265_43	1211814.CAPG01000037_gene2076	5.438e-19	91.0	2EQVH@1|root,33IFA@2|Bacteria,1VKS4@1239|Firmicutes,4HS0N@91061|Bacilli,1ZJ67@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2932265_18	1243664.CAVL020000025_gene1433	8.23e-126	417.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,4H9TJ@91061|Bacilli,1ZC1A@1386|Bacillus	91061|Bacilli	L	Flagellar Assembly Protein A	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
HKD2_k127_2932265_19	1403313.AXBR01000021_gene3076	9.736e-123	397.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,4HCJV@91061|Bacilli,1ZAPF@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigD	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD2_k127_2932265_27	1034347.CAHJ01000010_gene2051	3.467e-70	241.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4HIVG@91061|Bacilli,1ZGE3@1386|Bacillus	91061|Bacilli	NT	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
HKD2_k127_2932265_26	997296.PB1_00990	2.753e-91	304.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4HB40@91061|Bacilli,1ZDIE@1386|Bacillus	91061|Bacilli	NT	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation	cheC	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
HKD2_k127_2932265_32	1034347.CAHJ01000010_gene2053	5.886e-57	202.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,4HHB5@91061|Bacilli,1ZGZE@1386|Bacillus	91061|Bacilli	NT	COG0835 Chemotaxis signal transduction protein	cheW	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
HKD2_k127_2932265_1	345219.Bcoa_0034	1.218e-270	848.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus	91061|Bacilli	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
HKD2_k127_2932265_12	997296.PB1_01005	3.317e-147	475.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,4HBJY@91061|Bacilli,1ZC36@1386|Bacillus	91061|Bacilli	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
HKD2_k127_2932265_23	1174504.AJTN02000190_gene730	2.66e-110	363.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,4HCWZ@91061|Bacilli,1ZE3G@1386|Bacillus	91061|Bacilli	D	Belongs to the ParA family	ylxH	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
HKD2_k127_2932265_20	796606.BMMGA3_06210	2.462e-115	383.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1ZCJ9@1386|Bacillus	91061|Bacilli	N	Flagellar biosynthesis regulator FlhF	flhF	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
HKD2_k127_2932265_0	1174504.AJTN02000190_gene732	0.0	1072.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,1ZBID@1386|Bacillus	91061|Bacilli	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
HKD2_k127_2932265_11	1174504.AJTN02000190_gene733	1.854e-149	480.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,1ZBSH@1386|Bacillus	91061|Bacilli	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
HKD2_k127_2932265_22	1174504.AJTN02000190_gene734	3.624e-111	364.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,4HA2E@91061|Bacilli,1ZBJF@1386|Bacillus	91061|Bacilli	N	Flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
HKD2_k127_2932265_40	997296.PB1_01035	4.442e-34	132.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,4HKVS@91061|Bacilli,1ZI12@1386|Bacillus	91061|Bacilli	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
HKD2_k127_2932265_21	1243664.CAVL020000025_gene1447	6.422e-112	364.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,4HA79@91061|Bacilli,1ZCWT@1386|Bacillus	91061|Bacilli	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
HKD2_k127_2932265_35	1243664.CAVL020000025_gene1448	7e-48	179.0	COG3190@1|root,COG3190@2|Bacteria,1VGFI@1239|Firmicutes,4HJJQ@91061|Bacilli,1ZETY@1386|Bacillus	91061|Bacilli	N	Flagellar biosynthesis protein, FliO	fliZ	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
HKD2_k127_2932265_30	665959.HMPREF1013_00313	4.747e-62	214.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,4HGY2@91061|Bacilli,1ZG7Q@1386|Bacillus	91061|Bacilli	T	response regulator	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
HKD2_k127_2932265_10	1347368.HG964403_gene4700	1.104e-151	490.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,4HC56@91061|Bacilli,1ZB7S@1386|Bacillus	91061|Bacilli	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliY	GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
HKD2_k127_2932265_7	1174504.AJTN02000190_gene740	5.608e-171	541.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,4HAAY@91061|Bacilli,1ZCI6@1386|Bacillus	91061|Bacilli	N	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
HKD2_k127_2932265_37	1174504.AJTN02000190_gene741	5.297e-42	158.0	COG1580@1|root,COG1580@2|Bacteria,1V6K9@1239|Firmicutes,4HIJZ@91061|Bacilli,1ZI2U@1386|Bacillus	91061|Bacilli	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
HKD2_k127_2932265_42	935836.JAEL01000002_gene557	9.335e-21	94.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,4HP2W@91061|Bacilli,1ZIYN@1386|Bacillus	91061|Bacilli	N	protein, possibly involved in motility	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
HKD2_k127_2932265_17	997296.PB1_01075	2.039e-131	432.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,4IS7Y@91061|Bacilli,1ZS24@1386|Bacillus	91061|Bacilli	N	flagellar	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
HKD2_k127_2932265_38	1174504.AJTN02000190_gene744	5.352e-40	151.0	2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,4HMCM@91061|Bacilli,1ZHWB@1386|Bacillus	91061|Bacilli	N	Putative flagellar	flg	-	-	-	-	-	-	-	-	-	-	-	Flagellar_put
HKD2_k127_2932265_28	1174504.AJTN02000190_gene745	7.623e-69	239.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,4HNQK@91061|Bacilli,1ZI5S@1386|Bacillus	91061|Bacilli	N	Flagellar basal body rod modification protein	flgD	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD
HKD2_k127_2932265_31	1243664.CAVL020000025_gene1457	8.171e-58	219.0	COG3144@1|root,COG3144@2|Bacteria,1VI6B@1239|Firmicutes,4HGUR@91061|Bacilli,1ZJ6D@1386|Bacillus	91061|Bacilli	N	Flagellar hook-length control	fliK	GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
HKD2_k127_2932265_39	1243664.CAVL020000025_gene1458	3.386e-36	145.0	COG3334@1|root,COG3334@2|Bacteria,1V87H@1239|Firmicutes,4HM5Z@91061|Bacilli,1ZCXR@1386|Bacillus	91061|Bacilli	S	MgtE intracellular N domain	ylxF	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
HKD2_k127_2932265_34	1243664.CAVL020000025_gene1459	5.736e-50	181.0	COG2882@1|root,COG2882@2|Bacteria,1V6SQ@1239|Firmicutes,4HJZP@91061|Bacilli,1ZGXV@1386|Bacillus	91061|Bacilli	N	Flagellar biosynthesis chaperone	fliJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
HKD2_k127_2932265_3	796606.BMMGA3_06130	2.081e-220	690.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4HAUY@91061|Bacilli,1ZBXU@1386|Bacillus	91061|Bacilli	NU	COG1157 Flagellar biosynthesis type III secretory pathway ATPase	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD2_k127_2932265_33	1294265.JCM21738_300	8.325e-53	195.0	COG1317@1|root,COG1317@2|Bacteria,1VEUV@1239|Firmicutes,4HGNK@91061|Bacilli,1ZQRU@1386|Bacillus	91061|Bacilli	NU	Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
HKD2_k127_2932265_6	1174504.AJTN02000071_gene3966	1.361e-191	601.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,4HAFZ@91061|Bacilli,1ZAQU@1386|Bacillus	91061|Bacilli	N	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
HKD2_k127_2932265_5	935836.JAEL01000002_gene567	1.215e-202	643.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus	91061|Bacilli	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
HKD2_k127_2932265_41	35841.BT1A1_1559	2.833e-28	116.0	COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,4HNZW@91061|Bacilli,1ZIT0@1386|Bacillus	91061|Bacilli	N	Flagellar hook-basal body	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
HKD2_k127_2932265_29	1243664.CAVL020000025_gene1465	1.24e-65	226.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,4HH4W@91061|Bacilli,1ZGA0@1386|Bacillus	91061|Bacilli	N	Belongs to the flagella basal body rod proteins family	flgC	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD2_k127_2932265_36	665959.HMPREF1013_00330	6.443e-45	167.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,4HPTR@91061|Bacilli,1ZQN1@1386|Bacillus	91061|Bacilli	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
HKD2_k127_2932265_15	1403313.AXBR01000021_gene3083	2.634e-135	434.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli,1ZBT9@1386|Bacillus	91061|Bacilli	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
HKD2_k127_2932265_2	1403313.AXBR01000021_gene3084	1.341e-255	793.0	COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus	91061|Bacilli	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
HKD2_k127_2932265_25	1403313.AXBR01000021_gene3085	3.051e-93	310.0	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,1ZCMN@1386|Bacillus	91061|Bacilli	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
HKD2_k127_2932265_14	1403313.AXBR01000021_gene3086	7.45e-140	449.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,1ZB91@1386|Bacillus	91061|Bacilli	L	tyrosine recombinase XerC	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_2932265_4	1403313.AXBR01000021_gene3087	3.805e-210	656.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,1ZAR2@1386|Bacillus	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
HKD2_k127_293353_0	1403313.AXBR01000007_gene404	5.365e-121	390.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,1ZBNQ@1386|Bacillus	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD2_k127_293353_2	1174504.AJTN02000187_gene4761	6.515e-86	287.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,4HH1Y@91061|Bacilli,1ZFIY@1386|Bacillus	91061|Bacilli	S	Spore maturation protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
HKD2_k127_293353_3	345219.Bcoa_2917	3.377e-73	251.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,4HBTK@91061|Bacilli,1ZBSV@1386|Bacillus	91061|Bacilli	S	Spore maturation protein	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HKD2_k127_293353_1	1403313.AXBR01000007_gene407	4.503e-105	344.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,1ZBRQ@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacB	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD2_k127_293568_6	1403313.AXBR01000007_gene357	2.479e-84	280.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,1ZFJ7@1386|Bacillus	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HKD2_k127_293568_2	1403313.AXBR01000007_gene358	2.958e-164	522.0	COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,1ZAZ7@1386|Bacillus	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	hepT	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.30,2.5.1.83	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	-	R09245,R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD2_k127_293568_3	1403313.AXBR01000007_gene359	1.181e-120	390.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,1ZB6U@1386|Bacillus	91061|Bacilli	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HKD2_k127_293568_7	1403313.AXBR01000007_gene360	6.706e-84	286.0	COG0142@1|root,COG0142@2|Bacteria,1V1TG@1239|Firmicutes,4HFY5@91061|Bacilli,1ZQJT@1386|Bacillus	91061|Bacilli	H	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1	hepS	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	HEPPP_synt_1
HKD2_k127_293568_9	1403313.AXBR01000007_gene361	1.599e-34	133.0	2E4ES@1|root,32Z9Y@2|Bacteria,1VF84@1239|Firmicutes,4HNYS@91061|Bacilli,1ZHX6@1386|Bacillus	91061|Bacilli	K	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan	mtrB	-	-	ko:K06285	-	-	-	-	ko00000,ko03000	-	-	-	TrpBP
HKD2_k127_293568_4	1403313.AXBR01000007_gene362	3.146e-109	355.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,1ZAZD@1386|Bacillus	91061|Bacilli	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD2_k127_293568_11	1385514.N782_03495	8.03e-07	51.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_293568_8	1403313.AXBR01000007_gene363	3.814e-53	187.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZH48@1386|Bacillus	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hbs	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD2_k127_293568_0	1403313.AXBR01000007_gene364	4.817e-302	929.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,4HBH1@91061|Bacilli,1ZBNH@1386|Bacillus	91061|Bacilli	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
HKD2_k127_293568_5	1403313.AXBR01000007_gene365	3.797e-93	311.0	28J08@1|root,2Z8XG@2|Bacteria,1V177@1239|Firmicutes,4HCWC@91061|Bacilli,1ZCRV@1386|Bacillus	91061|Bacilli	-	-	yphF	-	-	-	-	-	-	-	-	-	-	-	DUF3939
HKD2_k127_293568_10	1033734.CAET01000076_gene3079	3.022e-20	92.0	2EJSH@1|root,33DH6@2|Bacteria,1VMUI@1239|Firmicutes,4HS5M@91061|Bacilli,1ZJ2B@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2768)	yphE	-	-	-	-	-	-	-	-	-	-	-	DUF2768
HKD2_k127_293568_1	1403313.AXBR01000007_gene369	5.349e-187	587.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus	91061|Bacilli	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD2_k127_2938852_4	1340434.AXVA01000010_gene5484	1.301e-06	50.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2938852_3	1403313.AXBR01000010_gene960	1.532e-33	134.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,1ZEKS@1386|Bacillus	91061|Bacilli	S	COG4980 Gas vesicle protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
HKD2_k127_2938852_1	1403313.AXBR01000010_gene961	1.792e-53	192.0	COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,1ZGYS@1386|Bacillus	91061|Bacilli	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	ytxG	-	-	-	-	-	-	-	-	-	-	-	DUF948
HKD2_k127_2938852_0	1403313.AXBR01000010_gene962	2.792e-221	689.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4HBUQ@91061|Bacilli,1ZD71@1386|Bacillus	91061|Bacilli	E	aminopeptidase	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
HKD2_k127_2938852_2	1243664.CAVL020000056_gene2394	2.248e-43	167.0	COG4314@1|root,COG4314@2|Bacteria,1V8NY@1239|Firmicutes,4HIVN@91061|Bacilli,1ZH9X@1386|Bacillus	91061|Bacilli	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
HKD2_k127_29608_1	1134413.ANNK01000091_gene48	9.915e-195	625.0	COG1719@1|root,COG3835@1|root,COG1719@2|Bacteria,COG3835@2|Bacteria,1TRK4@1239|Firmicutes,4HB2R@91061|Bacilli,1ZCZ8@1386|Bacillus	91061|Bacilli	KT	hydrocarbon binding protein (contains V4R domain)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,V4R,XylR_N
HKD2_k127_29608_3	666686.B1NLA3E_08475	1.273e-141	456.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	prmB	-	-	ko:K02823,ko:K18225,ko:K22356	ko00240,ko00625,ko00640,ko01100,ko01120,map00240,map00625,map00640,map01100,map01120	-	R05444,R10702,R11901	RC01383,RC03249	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD2_k127_29608_0	666686.B1NLA3E_08465	4.028e-266	825.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	-	ko:K16242	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002,ko01000	-	-	-	YHS,zf-FCS
HKD2_k127_29608_4	562970.Btus_0960	2.338e-31	125.0	2CJVU@1|root,301RP@2|Bacteria,1W0UR@1239|Firmicutes,4HZ21@91061|Bacilli	91061|Bacilli	C	MmoB/DmpM family	-	-	-	ko:K16244	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	MmoB_DmpM
HKD2_k127_29608_2	666686.B1NLA3E_08455	3.634e-168	535.0	2DB9W@1|root,2Z7Z9@2|Bacteria,1UCDJ@1239|Firmicutes,4HTJM@91061|Bacilli,1ZP0X@1386|Bacillus	91061|Bacilli	S	Methane/Phenol/Toluene Hydroxylase	-	-	-	ko:K16243	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002	-	-	-	Phenol_Hydrox
HKD2_k127_2985334_7	1340434.AXVA01000010_gene5484	2.798e-05	48.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_2985334_4	406124.ACPC01000007_gene3373	6.317e-72	247.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,4HIPC@91061|Bacilli,1ZG08@1386|Bacillus	91061|Bacilli	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
HKD2_k127_2985334_6	666686.B1NLA3E_02975	3.99e-17	85.0	COG0697@1|root,COG0697@2|Bacteria,1TRJZ@1239|Firmicutes,4HDJI@91061|Bacilli,1ZCMU@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	yvbV	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_2985334_1	666686.B1NLA3E_10000	5.811e-114	372.0	COG1117@1|root,COG1117@2|Bacteria,1V2UH@1239|Firmicutes,4HDCU@91061|Bacilli,1ZDW3@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	yjkB	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HKD2_k127_2985334_0	666686.B1NLA3E_10005	5.6e-121	392.0	COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,1ZB6C@1386|Bacillus	91061|Bacilli	S	transport system, permease component	ybbM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
HKD2_k127_2985334_2	1347369.CCAD010000078_gene2948	1.311e-102	337.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,4HDC7@91061|Bacilli,1ZBS1@1386|Bacillus	91061|Bacilli	S	membrane	yvgT	-	-	-	-	-	-	-	-	-	-	-	UPF0126
HKD2_k127_2985334_3	666686.B1NLA3E_12560	1.591e-76	258.0	COG3773@1|root,COG3773@2|Bacteria,1V3QK@1239|Firmicutes,4HH00@91061|Bacilli,1ZGB9@1386|Bacillus	91061|Bacilli	M	Cell wall	cwlJ	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
HKD2_k127_2985334_5	1174504.AJTN02000034_gene3481	2.175e-56	200.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli,1ZCJD@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
HKD2_k127_307109_0	926690.KE386573_gene103	1.115e-109	363.0	COG0388@1|root,arCOG00062@2157|Archaea,2XVVK@28890|Euryarchaeota,23US8@183963|Halobacteria	183963|Halobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
HKD2_k127_307109_1	189753.AXAS01000102_gene5978	2.464e-78	276.0	COG0683@1|root,COG0683@2|Bacteria,1MUZU@1224|Proteobacteria,2TS7Z@28211|Alphaproteobacteria,3JV40@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	MA20_08735	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_5,Peripla_BP_6
HKD2_k127_307109_2	189753.AXAS01000066_gene6114	1.656e-60	219.0	COG0559@1|root,COG0559@2|Bacteria,1P4N0@1224|Proteobacteria,2U1CE@28211|Alphaproteobacteria,3JVN5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11960	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
HKD2_k127_307109_3	189753.AXAS01000102_gene5976	1.732e-60	222.0	COG4177@1|root,COG4177@2|Bacteria,1MWRD@1224|Proteobacteria,2TS03@28211|Alphaproteobacteria,3JW99@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
HKD2_k127_307109_4	1261545.MBE-HAL_2218	1.375e-07	53.0	COG4674@1|root,arCOG00927@2157|Archaea,2XURA@28890|Euryarchaeota,23UDA@183963|Halobacteria	183963|Halobacteria	E	ABC transporter, ATP-binding protein	urtD	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
HKD2_k127_3077357_0	1196322.A370_03070	2.181e-80	275.0	COG2230@1|root,COG2230@2|Bacteria,1UJ6V@1239|Firmicutes,25EX4@186801|Clostridia,36HJD@31979|Clostridiaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD2_k127_3077357_1	420247.Msm_0713	4.53e-27	117.0	COG1936@1|root,arCOG01038@2157|Archaea,2XX2A@28890|Euryarchaeota,23P4V@183925|Methanobacteria	183925|Methanobacteria	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
HKD2_k127_3081655_12	562743.JH976434_gene1029	5.068e-17	83.0	29JKI@1|root,2ZUBB@2|Bacteria,1W57X@1239|Firmicutes,4I1CV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3081655_9	1211814.CAPG01000074_gene3473	6.897e-28	113.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,4HS76@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
HKD2_k127_3081655_15	1307436.PBF_22023	7.772e-06	53.0	COG0677@1|root,COG0677@2|Bacteria,1V98N@1239|Firmicutes,4HK57@91061|Bacilli,1ZQY8@1386|Bacillus	91061|Bacilli	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3081655_7	1132442.KB889752_gene501	3.254e-33	136.0	COG1403@1|root,COG1403@2|Bacteria,1U3M9@1239|Firmicutes,4HY8U@91061|Bacilli	91061|Bacilli	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3081655_8	1121087.AUCK01000002_gene2474	8.624e-31	128.0	COG2963@1|root,COG2963@2|Bacteria,1V6XW@1239|Firmicutes,4HIUS@91061|Bacilli,1ZNRZ@1386|Bacillus	91061|Bacilli	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23
HKD2_k127_3081655_0	981383.AEWH01000067_gene226	7.009e-235	734.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli	91061|Bacilli	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
HKD2_k127_3081655_1	1121091.AUMP01000003_gene2583	3.521e-233	736.0	28N6S@1|root,2ZBBK@2|Bacteria,1V2EC@1239|Firmicutes,4HV2Y@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
HKD2_k127_3081655_5	1134413.ANNK01000120_gene2028	3.603e-42	156.0	2AJ1X@1|root,319K5@2|Bacteria,1U7WC@1239|Firmicutes,4IHTR@91061|Bacilli,1ZNH3@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2829)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2829
HKD2_k127_3081655_6	1134413.ANNK01000120_gene2029	3.399e-40	149.0	2AHSZ@1|root,3185G@2|Bacteria,1UCU6@1239|Firmicutes,4IPAC@91061|Bacilli,1ZPME@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3081655_4	1121091.AUMP01000003_gene2584	1.824e-64	229.0	2DXGY@1|root,344ZF@2|Bacteria,1VZG6@1239|Firmicutes,4HYHP@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3081655_2	1121091.AUMP01000003_gene2585	5.814e-177	557.0	28W6R@1|root,2ZI7D@2|Bacteria,1V1MZ@1239|Firmicutes,4HTYQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3081655_3	871968.DESME_08885	2.989e-103	359.0	28PXR@1|root,2ZCHM@2|Bacteria,1V24G@1239|Firmicutes,24G17@186801|Clostridia,265R8@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3081655_14	398767.Glov_2915	1.923e-06	60.0	COG0028@1|root,COG1361@1|root,COG3468@1|root,COG5492@1|root,COG0028@2|Bacteria,COG1361@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
HKD2_k127_3102149_0	1340434.AXVA01000023_gene3355	1.771e-303	934.0	COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus	91061|Bacilli	E	arginine degradation protein	rocB	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M20
HKD2_k127_3134041_2	1403313.AXBR01000025_gene4989	6.148e-56	197.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,1ZG84@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HKD2_k127_3134041_1	1403313.AXBR01000025_gene4988	3.5e-103	338.0	COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,1ZBPR@1386|Bacillus	91061|Bacilli	J	Methyltransferase	rsmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
HKD2_k127_3134041_0	1403313.AXBR01000025_gene4987	0.0	1889.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HKD2_k127_3137483_5	1174504.AJTN02000243_gene4284	3.239e-28	115.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD2_k127_3137483_2	1444310.JANV01000154_gene2307	2.769e-123	400.0	COG4813@1|root,COG4813@2|Bacteria,1TPZ1@1239|Firmicutes,4HARS@91061|Bacilli,1ZC3B@1386|Bacillus	91061|Bacilli	G	Trehalose utilisation	thuA	-	-	-	-	-	-	-	-	-	-	-	ThuA
HKD2_k127_3137483_4	666686.B1NLA3E_01710	9.755e-48	174.0	COG2259@1|root,COG2259@2|Bacteria,1VQEW@1239|Firmicutes,4HXTP@91061|Bacilli	91061|Bacilli	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD2_k127_3137483_0	1403313.AXBR01000002_gene4447	4.045e-198	631.0	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
HKD2_k127_3137483_3	1403313.AXBR01000023_gene2642	4.454e-118	388.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HB6E@91061|Bacilli,1ZQNX@1386|Bacillus	91061|Bacilli	S	Na -dependent transporter	ybaS	-	-	-	-	-	-	-	-	-	-	-	SBF,SBF_like
HKD2_k127_3137483_1	649747.HMPREF0083_01895	3.173e-193	607.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,26UWU@186822|Paenibacillaceae	91061|Bacilli	I	Acyl--CoA ligase	acsA1	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_314850_3	1134413.ANNK01000054_gene2195	5.437e-21	95.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,4IT0E@91061|Bacilli,1ZSHN@1386|Bacillus	91061|Bacilli	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
HKD2_k127_314850_2	1033734.CAET01000069_gene2466	2.214e-142	462.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,4HBFI@91061|Bacilli,1ZD1H@1386|Bacillus	91061|Bacilli	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HKD2_k127_314850_1	1385513.N780_02820	6.53e-162	515.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,2Y97X@289201|Pontibacillus	91061|Bacilli	NU	Twitching motility protein PilT	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HKD2_k127_314850_0	1385511.N783_08825	1.585e-181	575.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,2Y9KV@289201|Pontibacillus	91061|Bacilli	NU	Type II secretion system protein E	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
HKD2_k127_3154652_6	1403313.AXBR01000022_gene2820	2.017e-24	102.0	COG0316@1|root,COG0316@2|Bacteria,1VB5R@1239|Firmicutes,4HKPI@91061|Bacilli,1ZGXR@1386|Bacillus	91061|Bacilli	S	Heme biosynthesis protein HemY	-	-	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	-
HKD2_k127_3154652_0	1117379.BABA_12116	6.504e-212	664.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZC6E@1386|Bacillus	91061|Bacilli	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD2_k127_3154652_2	1403313.AXBR01000022_gene2803	4.433e-131	430.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,4HDAX@91061|Bacilli,1ZCUD@1386|Bacillus	91061|Bacilli	M	protein conserved in bacteria	spl	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HKD2_k127_3154652_4	1403313.AXBR01000022_gene2802	2.789e-50	182.0	2D46J@1|root,32TGE@2|Bacteria,1VD1S@1239|Firmicutes,4HKFR@91061|Bacilli,1ZIVT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3154652_5	1121090.KB894696_gene77	7.1e-33	129.0	2DTR5@1|root,33MCD@2|Bacteria,1VH2H@1239|Firmicutes,4HQ9N@91061|Bacilli,1ZI67@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2653)	yxcD	-	-	-	-	-	-	-	-	-	-	-	DUF2653
HKD2_k127_3154652_3	1403313.AXBR01000022_gene2797	2.492e-121	394.0	COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HD7T@91061|Bacilli,1ZGIF@1386|Bacillus	91061|Bacilli	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HKD2_k127_3154652_1	1243664.CAVL020000008_gene4050	2.034e-138	447.0	COG1960@1|root,COG1960@2|Bacteria,1V0U8@1239|Firmicutes,4HEJX@91061|Bacilli,1ZF9H@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_3159755_2	997296.PB1_07317	1.392e-119	386.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,1ZB67@1386|Bacillus	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD2_k127_3159755_0	574376.BAMA_12640	2.144e-228	713.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HKD2_k127_3159755_3	315749.Bcer98_4026	2.933e-119	387.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,1ZBYD@1386|Bacillus	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HKD2_k127_3159755_4	1169144.KB910926_gene1097	7.729e-44	163.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,1ZHUH@1386|Bacillus	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD2_k127_3159755_5	491915.Aflv_2863	7.747e-17	81.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,21VVM@150247|Anoxybacillus	91061|Bacilli	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD2_k127_3159755_1	1169144.KB910926_gene1095	4.062e-146	465.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD2_k127_3192899_0	1403313.AXBR01000027_gene5265	4.464e-224	696.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus	91061|Bacilli	S	COG1078 HD superfamily phosphohydrolases	ywfO	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
HKD2_k127_3192899_17	1294265.JCM21738_1787	3.471e-07	57.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD2_k127_3192899_12	1403313.AXBR01000027_gene5266	5.953e-38	142.0	COG4844@1|root,COG4844@2|Bacteria,1VB5Q@1239|Firmicutes,4HKJX@91061|Bacilli,1ZHXV@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0741 family	ywzC	-	-	-	-	-	-	-	-	-	-	-	DUF1450
HKD2_k127_3192899_5	1403313.AXBR01000027_gene5267	3.908e-109	357.0	2C8MW@1|root,2ZCFU@2|Bacteria,1V10H@1239|Firmicutes,4HE3P@91061|Bacilli,1ZCQG@1386|Bacillus	91061|Bacilli	S	Transcriptional regulator	rsfA	-	-	ko:K06314	-	-	-	-	ko00000,ko03000	-	-	-	Myb_DNA-bind_6
HKD2_k127_3192899_3	1403313.AXBR01000027_gene5268	6.007e-130	419.0	COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,1ZCIA@1386|Bacillus	91061|Bacilli	H	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes	lipL	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.200,2.3.1.204	ko:K16869,ko:K18821	-	-	-	-	ko00000,ko01000	-	-	-	BPL_LplA_LipB
HKD2_k127_3192899_1	997296.PB1_07807	6.952e-159	507.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,1ZC98@1386|Bacillus	91061|Bacilli	C	In Salmonella this enzyme is required for ethanolamine catabolism	pta	-	2.3.1.8,3.6.3.21	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00236,M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	iSB619.SA_RS03155	PTA_PTB
HKD2_k127_3192899_2	1403313.AXBR01000027_gene5270	4.383e-144	459.0	COG3253@1|root,COG3253@2|Bacteria,1TQB2@1239|Firmicutes,4H9YI@91061|Bacilli,1ZAZY@1386|Bacillus	91061|Bacilli	C	May function as heme-dependent peroxidase	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
HKD2_k127_3192899_9	1403313.AXBR01000027_gene5271	9.571e-61	215.0	2CWP1@1|root,32T03@2|Bacteria,1VAD2@1239|Firmicutes,4HKGQ@91061|Bacilli,1ZH2J@1386|Bacillus	91061|Bacilli	S	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA	gerQ	GO:0005575,GO:0005618,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0019538,GO:0030312,GO:0031160,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0071944,GO:1901564	-	ko:K06305	-	-	-	-	ko00000	-	-	-	Spore_GerQ
HKD2_k127_3192899_11	1403313.AXBR01000027_gene5272	2.4e-54	192.0	COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli,1ZGYJ@1386|Bacillus	91061|Bacilli	S	small membrane protein	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
HKD2_k127_3192899_14	1501230.ET33_25875	3.588e-18	85.0	2EH2E@1|root,33AUC@2|Bacteria,1VMDA@1239|Firmicutes,4HRKE@91061|Bacilli,273YF@186822|Paenibacillaceae	91061|Bacilli	S	Uracil-DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3192899_7	1174504.AJTN02000251_gene2980	1.866e-100	331.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,1ZBCY@1386|Bacillus	91061|Bacilli	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HKD2_k127_3192899_4	1243664.CAVL020000058_gene4414	1.1e-121	396.0	COG0583@1|root,COG0583@2|Bacteria,1V1MH@1239|Firmicutes,4HFVE@91061|Bacilli,1ZD99@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	citR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K19242	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HKD2_k127_3192899_8	1243664.CAVL020000058_gene4415	2.121e-99	329.0	COG0500@1|root,COG2226@2|Bacteria,1V261@1239|Firmicutes,4HI81@91061|Bacilli,1ZAPH@1386|Bacillus	91061|Bacilli	Q	O-methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
HKD2_k127_3192899_10	1403313.AXBR01000027_gene5283	1.376e-55	196.0	COG2120@1|root,COG2120@2|Bacteria,1VA8Q@1239|Firmicutes,4HKMK@91061|Bacilli,1ZH30@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1806)	yojF	-	-	-	-	-	-	-	-	-	-	-	DUF1806
HKD2_k127_3192899_6	1403313.AXBR01000027_gene5284	1.758e-105	346.0	COG2120@1|root,COG2120@2|Bacteria,1TPSJ@1239|Firmicutes,4HA2P@91061|Bacilli,1ZB3T@1386|Bacillus	91061|Bacilli	S	deacetylase	bshB2	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
HKD2_k127_3192899_13	946235.CAER01000060_gene3279	2.873e-18	85.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,23K34@182709|Oceanobacillus	91061|Bacilli	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_3192982_3	1294265.JCM21738_1173	1.148e-54	195.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,4HAQ2@91061|Bacilli,1ZBZF@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD2_k127_3192982_1	1384049.CD29_14915	2.716e-66	229.0	COG0454@1|root,COG0456@2|Bacteria,1V7Q4@1239|Firmicutes,4HHHA@91061|Bacilli,3IY7J@400634|Lysinibacillus	91061|Bacilli	K	GNAT family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD2_k127_3192982_2	491915.Aflv_1549	1.694e-58	224.0	2EEBD@1|root,3385Q@2|Bacteria,1VEQZ@1239|Firmicutes,4HPXT@91061|Bacilli,21WVV@150247|Anoxybacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3192982_0	1305836.AXVE01000004_gene1305	1.222e-69	241.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26GSH@186818|Planococcaceae	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD2_k127_3192982_4	1169144.KB910952_gene3183	1.989e-53	193.0	COG1277@1|root,COG1277@2|Bacteria,1V2P1@1239|Firmicutes,4HG7C@91061|Bacilli,1ZG5K@1386|Bacillus	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD2_k127_3207_2	1403313.AXBR01000014_gene2257	6.126e-115	375.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HA1X@91061|Bacilli,1ZCDN@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	gltC	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K09681	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HKD2_k127_3207_0	1403313.AXBR01000014_gene2258	0.0	2498.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus	91061|Bacilli	E	glutamate synthase	gltA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD2_k127_3207_1	545693.BMQ_2099	2.431e-280	866.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,1ZC3C@1386|Bacillus	91061|Bacilli	E	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
HKD2_k127_3207_4	1307436.PBF_18114	2.702e-30	123.0	COG4858@1|root,COG4858@2|Bacteria,1V8U0@1239|Firmicutes,4HIMP@91061|Bacilli,1ZFXH@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3207_3	1121091.AUMP01000015_gene667	4.056e-46	168.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli	91061|Bacilli	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD2_k127_3250349_4	647113.Metok_0539	3.762e-23	102.0	COG0076@1|root,arCOG00027@2157|Archaea,2XT09@28890|Euryarchaeota,23QHF@183939|Methanococci	183939|Methanococci	F	Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis	mfnA	GO:0003674,GO:0003824,GO:0004068,GO:0004837,GO:0005488,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019842,GO:0030170,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070279,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001119,GO:2001120	4.1.1.11,4.1.1.25	ko:K18933	ko00350,ko00410,ko00680,ko00770,ko01100,ko01110,map00350,map00410,map00680,map00770,map01100,map01110	-	R00489,R00736	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
HKD2_k127_3250349_1	671143.DAMO_2657	2.492e-55	209.0	COG1821@1|root,COG1821@2|Bacteria	2|Bacteria	GM	Pfam ATP-grasp domain	-	-	6.3.4.24	ko:K06914	ko00680,map00680	-	R10902	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_3
HKD2_k127_3250349_0	634498.mru_1695	5.39e-69	247.0	COG1548@1|root,arCOG04369@2157|Archaea,2XVPP@28890|Euryarchaeota,23NVV@183925|Methanobacteria	183925|Methanobacteria	K	H4MPT-linked C1 transfer pathway protein	-	-	2.5.1.131	ko:K07072	ko00680,map00680	-	R11040	RC01372,RC03335	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_A
HKD2_k127_3250349_3	877455.Metbo_0405	4.637e-40	158.0	COG2054@1|root,arCOG00859@2157|Archaea,2XVEI@28890|Euryarchaeota,23P3Z@183925|Methanobacteria	183925|Methanobacteria	S	aspartate glutamate uridylate kinase	-	-	2.7.4.31	ko:K07144	ko00680,map00680	-	R11039	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD2_k127_3250349_2	247490.KSU1_D0178	1.303e-46	174.0	COG2410@1|root,COG2410@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF429)	-	-	-	ko:K09147	-	-	-	-	ko00000	-	-	-	DUF429
HKD2_k127_3250349_6	633148.Tagg_0901	3.781e-05	51.0	COG3432@1|root,arCOG01055@2157|Archaea,2XSK9@28889|Crenarchaeota	28889|Crenarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
HKD2_k127_3250349_8	1121947.AUHK01000004_gene1078	7.8e-05	52.0	COG3428@1|root,COG3428@2|Bacteria,1VD6M@1239|Firmicutes,24VEW@186801|Clostridia	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
HKD2_k127_3250349_5	195522.BD01_1385	7.052e-11	70.0	COG0727@1|root,arCOG02579@2157|Archaea,2Y268@28890|Euryarchaeota,24416@183968|Thermococci	183968|Thermococci	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD2_k127_3250349_7	272557.APE_0179a	5.68e-05	48.0	arCOG04057@1|root,arCOG04057@2157|Archaea	2157|Archaea	J	Belongs to the eukaryotic ribosomal protein eL38 family	rpl38e	-	-	ko:K02923	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L38e
HKD2_k127_3267836_3	1121289.JHVL01000014_gene1763	1.339e-46	173.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,36EQ4@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD2_k127_3267836_1	1243664.CAVL020000049_gene5084	5.922e-141	451.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,1ZCDW@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_3267836_0	1243664.CAVL020000049_gene5085	6.953e-154	492.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4IUPS@91061|Bacilli,1ZSIB@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HKD2_k127_3267836_2	1243664.CAVL020000049_gene5086	6.029e-119	386.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,1ZDT5@1386|Bacillus	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_3267836_4	1403313.AXBR01000009_gene786	1.259e-43	159.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
HKD2_k127_328186_2	1034347.CAHJ01000084_gene1339	7.064e-134	426.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1ZQ3H@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	bglA	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HKD2_k127_328186_4	1034347.CAHJ01000084_gene1340	3.007e-46	168.0	COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,1ZI2Z@1386|Bacillus	91061|Bacilli	G	phosphotransferase system	licA	-	2.7.1.196,2.7.1.205,2.7.1.207	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	M00275,M00281	R04393,R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.1,4.A.3.2	-	iYO844.BSU38570	PTS_IIA
HKD2_k127_328186_0	1034347.CAHJ01000084_gene1341	1.248e-223	699.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,1ZBJ7@1386|Bacillus	91061|Bacilli	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	licC	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	iYO844.BSU38390	PTS_EIIC
HKD2_k127_328186_3	1034347.CAHJ01000084_gene1342	6.228e-49	176.0	COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HM5Q@91061|Bacilli,1ZIC3@1386|Bacillus	91061|Bacilli	G	transporter subunit IIB	licB	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
HKD2_k127_328186_1	1034347.CAHJ01000084_gene1343	1.145e-189	598.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,1ZQ0I@1386|Bacillus	91061|Bacilli	GKT	Mga helix-turn-helix domain	licR	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
HKD2_k127_332933_2	1227352.C173_14610	1.04e-50	186.0	COG1434@1|root,COG1434@2|Bacteria,1VB45@1239|Firmicutes,4HMVM@91061|Bacilli,26U1E@186822|Paenibacillaceae	91061|Bacilli	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD2_k127_332933_5	1403313.AXBR01000022_gene2709	9.487e-42	159.0	COG1595@1|root,COG1595@2|Bacteria,1VFHW@1239|Firmicutes,4HQ70@91061|Bacilli,1ZIYW@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD2_k127_332933_6	1174504.AJTN02000213_gene2528	1.076e-26	117.0	2C6U3@1|root,304U1@2|Bacteria,1U9UP@1239|Firmicutes,4IK2E@91061|Bacilli,1ZKMA@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_332933_4	1403313.AXBR01000015_gene2115	3.3e-43	174.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,1ZS4T@1386|Bacillus	91061|Bacilli	F	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases	cpdB	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,CHB_HEX_C_1,Gram_pos_anchor,Metallophos,SLH
HKD2_k127_332933_1	1408303.JNJJ01000001_gene3851	1.409e-123	401.0	COG2217@1|root,COG2217@2|Bacteria,1UHSD@1239|Firmicutes,4IS9K@91061|Bacilli,1ZS3Q@1386|Bacillus	91061|Bacilli	P	EcsC protein family	ydbA	-	-	-	-	-	-	-	-	-	-	-	EcsC
HKD2_k127_332933_3	1408303.JNJJ01000124_gene4024	1.052e-48	180.0	COG1943@1|root,COG1943@2|Bacteria,1V6R5@1239|Firmicutes,4HGQT@91061|Bacilli,1ZFV8@1386|Bacillus	91061|Bacilli	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD2_k127_332933_0	1403313.AXBR01000026_gene5168	6.683e-131	426.0	COG2385@1|root,COG2385@2|Bacteria,1V9XE@1239|Firmicutes,4HDNT@91061|Bacilli,1ZF67@1386|Bacillus	91061|Bacilli	D	Stage II sporulation protein	lytB	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	CW_binding_2,PG_binding_1,SH3_3,SpoIID
HKD2_k127_3394940_0	1227360.C176_00335	0.0	1523.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,26F0S@186818|Planococcaceae	91061|Bacilli	M	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8,SLH
HKD2_k127_3394940_1	1174504.AJTN02000010_gene4498	1.267e-310	966.0	COG0653@1|root,COG0653@2|Bacteria,1TSCF@1239|Firmicutes,4HBNY@91061|Bacilli,1ZD65@1386|Bacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0022804,GO:0022857,GO:0022884,GO:0032940,GO:0033036,GO:0042886,GO:0042887,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD2_k127_3422927_3	335543.Sfum_0966	3.252e-24	105.0	2F478@1|root,33WY8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3422927_0	335543.Sfum_0965	1.728e-170	554.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria	1224|Proteobacteria	E	asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD2_k127_3422927_1	335543.Sfum_0963	9.113e-72	259.0	COG3307@1|root,COG3307@2|Bacteria,1Q4PM@1224|Proteobacteria,42ZKE@68525|delta/epsilon subdivisions,2WUZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HKD2_k127_3422927_2	935840.JAEQ01000003_gene100	8.112e-31	131.0	COG0726@1|root,COG0726@2|Bacteria,1R881@1224|Proteobacteria,2U1Y9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_3463652_2	1034769.KB910518_gene3974	1.149e-26	112.0	28XPJ@1|root,2ZJKD@2|Bacteria,1W2F3@1239|Firmicutes,4HZUY@91061|Bacilli,26ZVA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3463652_6	491915.Aflv_0781	0.0003352	48.0	2BZUZ@1|root,32YFC@2|Bacteria,1VHUY@1239|Firmicutes,4HPTS@91061|Bacilli,21VYC@150247|Anoxybacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3463652_1	1382358.JHVN01000024_gene1694	1.749e-69	243.0	COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HDFH@91061|Bacilli,21WS1@150247|Anoxybacillus	91061|Bacilli	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HKD2_k127_3463652_0	574376.BAMA_12440	9.133e-94	315.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,4HH4U@91061|Bacilli,1ZH4M@1386|Bacillus	91061|Bacilli	L	IstB-like ATP binding protein	-	-	-	ko:K02315,ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HKD2_k127_3463652_4	649639.Bcell_2749	1.903e-06	55.0	2AJFQ@1|root,31A21@2|Bacteria,1U8MS@1239|Firmicutes,4IIJS@91061|Bacilli,1ZNPH@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3515817_0	1131730.BAVI_25155	5.665e-126	411.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus	91061|Bacilli	T	Histidine kinase	ykoH3	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_3515817_1	1131730.BAVI_25160	2.242e-113	370.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,1ZD1X@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ykoG3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_3515817_3	1174504.AJTN02000200_gene3539	7.967e-35	136.0	2CDZ2@1|root,32RYS@2|Bacteria,1VABM@1239|Firmicutes,4HKKB@91061|Bacilli,1ZHT7@1386|Bacillus	91061|Bacilli	S	Putative membrane protein	yuiB	-	-	-	-	-	-	-	-	-	-	-	YuiB
HKD2_k127_3515817_2	1403313.AXBR01000013_gene1458	2.54e-72	246.0	COG1051@1|root,COG1051@2|Bacteria,1V4TX@1239|Firmicutes,4HH70@91061|Bacilli,1ZGXJ@1386|Bacillus	91061|Bacilli	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_3515817_4	1340434.AXVA01000010_gene5484	8.46e-08	56.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_354606_4	1347369.CCAD010000072_gene3581	3.156e-29	133.0	COG0642@1|root,COG2205@2|Bacteria,1UPFH@1239|Firmicutes,4IV44@91061|Bacilli,1ZG3M@1386|Bacillus	91061|Bacilli	T	Membrane-associated sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	MASE3
HKD2_k127_354606_1	1444309.JAQG01000015_gene1598	1.036e-47	190.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HAUU@91061|Bacilli,26TU8@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	nreB	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
HKD2_k127_354606_2	1499680.CCFE01000033_gene3982	2.256e-34	137.0	COG0835@1|root,COG0835@2|Bacteria,1U32S@1239|Firmicutes,4I55E@91061|Bacilli,1ZJ58@1386|Bacillus	91061|Bacilli	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
HKD2_k127_354606_0	1227352.C173_27540	6.593e-219	707.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,4HEHQ@91061|Bacilli,26QYN@186822|Paenibacillaceae	91061|Bacilli	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	-	-	-	-	-	-	-	-	-	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
HKD2_k127_354606_3	756499.Desde_1657	1.214e-31	136.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,261XC@186807|Peptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,sCache_2
HKD2_k127_3658947_6	1051501.AYTL01000030_gene2388	7.632e-66	228.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus	91061|Bacilli	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
HKD2_k127_3658947_11	1294265.JCM21738_1838	1.225e-06	51.0	COG4768@1|root,COG4768@2|Bacteria,1UBBB@1239|Firmicutes,4IMQ8@91061|Bacilli,1ZKKT@1386|Bacillus	91061|Bacilli	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
HKD2_k127_3658947_9	1403313.AXBR01000007_gene300	1.27e-37	148.0	29NR8@1|root,309P6@2|Bacteria,1U5F9@1239|Firmicutes,4IF6W@91061|Bacilli,1ZJ7A@1386|Bacillus	91061|Bacilli	S	YppG-like protein	yppG	-	-	-	-	-	-	-	-	-	-	-	YppG
HKD2_k127_3658947_8	1403313.AXBR01000007_gene302	5.346e-40	152.0	2C8E7@1|root,32RKZ@2|Bacteria,1VIES@1239|Firmicutes,4HKFC@91061|Bacilli,1ZITF@1386|Bacillus	91061|Bacilli	S	Bacterial domain of unknown function (DUF1798)	yppE	-	-	-	-	-	-	-	-	-	-	-	DUF1798
HKD2_k127_3658947_12	1347369.CCAD010000022_gene1664	0.0004293	44.0	COG1835@1|root,COG1835@2|Bacteria,1UNRM@1239|Firmicutes,4IUMP@91061|Bacilli,1ZBMH@1386|Bacillus	91061|Bacilli	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD2_k127_3658947_3	1403313.AXBR01000007_gene304	9.523e-117	382.0	28MSG@1|root,2ZB0U@2|Bacteria,1TT1H@1239|Firmicutes,4HBNQ@91061|Bacilli,1ZCHW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2515)	yppC	-	-	-	-	-	-	-	-	-	-	-	DUF2515
HKD2_k127_3658947_5	1403313.AXBR01000007_gene305	1.354e-94	313.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,1ZCV9@1386|Bacillus	91061|Bacilli	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
HKD2_k127_3658947_0	1403313.AXBR01000007_gene306	0.0	1178.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	ponA	GO:0005575,GO:0005576	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,fn3
HKD2_k127_3658947_7	1403313.AXBR01000007_gene307	5.591e-42	160.0	2EGVD@1|root,33AMM@2|Bacteria,1VKVK@1239|Firmicutes,4HRYS@91061|Bacilli,1ZITC@1386|Bacillus	91061|Bacilli	-	-	ypoC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3658947_2	1403313.AXBR01000007_gene308	9.036e-125	401.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,1ZBJE@1386|Bacillus	91061|Bacilli	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD2_k127_3658947_4	1174504.AJTN02000249_gene790	5.135e-104	343.0	COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,1ZC34@1386|Bacillus	91061|Bacilli	L	DNA replication protein DnaD	dnaD	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2,HTH_36
HKD2_k127_3658947_1	1403313.AXBR01000007_gene310	1.951e-253	785.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,1ZC51@1386|Bacillus	91061|Bacilli	J	asparaginyl-tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD2_k127_3668841_13	1403313.AXBR01000023_gene2438	1.47e-07	58.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1ZB1W@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0754 family	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD2_k127_3668841_12	1385514.N782_03495	4.856e-09	58.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3668841_9	1403313.AXBR01000023_gene2437	1.068e-50	182.0	COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,1ZH14@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0342 family	yheA	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HKD2_k127_3668841_5	1403313.AXBR01000023_gene2436	2.265e-132	427.0	COG0561@1|root,COG0561@2|Bacteria,1V2XI@1239|Firmicutes,4HG2U@91061|Bacilli,1ZB1F@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	yhaX	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HKD2_k127_3668841_8	1403313.AXBR01000023_gene2434	2.452e-52	188.0	COG2318@1|root,COG2318@2|Bacteria,1VCS4@1239|Firmicutes,4HM90@91061|Bacilli,1ZERV@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD2_k127_3668841_7	1403313.AXBR01000023_gene2428	1.92e-101	336.0	COG1024@1|root,COG1024@2|Bacteria,1TRCQ@1239|Firmicutes,4HDUU@91061|Bacilli,1ZARB@1386|Bacillus	91061|Bacilli	I	enoyl-CoA hydratase	yhaR	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD2_k127_3668841_10	1403313.AXBR01000023_gene2427	2.423e-25	105.0	2E4GP@1|root,32ZBV@2|Bacteria,1VF2A@1239|Firmicutes,4HNUS@91061|Bacilli,1ZIT1@1386|Bacillus	91061|Bacilli	S	YhzD-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhzD
HKD2_k127_3668841_6	1408424.JHYI01000046_gene1573	1.843e-111	367.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,1ZC9T@1386|Bacillus	91061|Bacilli	S	ABC transporter, ATP-binding protein	yhaQ	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD2_k127_3668841_3	1403313.AXBR01000018_gene3470	3.995e-153	494.0	COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,1ZBM6@1386|Bacillus	91061|Bacilli	CP	COG1668 ABC-type Na efflux pump, permease component	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD2_k127_3668841_1	1403313.AXBR01000023_gene2426	4.008e-164	520.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZC73@1386|Bacillus	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	ytkP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD2_k127_3668841_0	1403313.AXBR01000023_gene2417	4.346e-179	564.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,1ZB1G@1386|Bacillus	91061|Bacilli	L	Shows a 3'-5' exoribonuclease activity	yhaM	GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
HKD2_k127_3668841_2	1291050.JAGE01000002_gene3609	1.981e-160	512.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
HKD2_k127_3668841_4	315730.BcerKBAB4_1012	1.121e-134	433.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,4HBGV@91061|Bacilli,1ZCMQ@1386|Bacillus	91061|Bacilli	O	COG0555 ABC-type sulfate transport system, permease component	cysT	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
HKD2_k127_3691131_1	1305836.AXVE01000001_gene2726	5.354e-77	259.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,26EAW@186818|Planococcaceae	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
HKD2_k127_3691131_3	1236973.JCM9157_1034	2.672e-18	87.0	2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus	91061|Bacilli	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
HKD2_k127_3691131_2	997296.PB1_07492	1.038e-28	117.0	2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus	91061|Bacilli	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
HKD2_k127_3691131_0	1122918.KB907256_gene2356	4.851e-111	361.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,26QCC@186822|Paenibacillaceae	91061|Bacilli	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	XK27_00915	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_3698450_2	1395587.P364_0109945	3.324e-59	214.0	COG1653@1|root,COG1653@2|Bacteria,1TQ1D@1239|Firmicutes,4HC43@91061|Bacilli,26SVN@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_8
HKD2_k127_3698450_1	1395587.P364_0109940	9.071e-121	394.0	COG0395@1|root,COG0395@2|Bacteria,1TSKG@1239|Firmicutes,4HCDM@91061|Bacilli,26QAF@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter permease	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
HKD2_k127_3698450_0	1395587.P364_0109935	5.87e-130	422.0	COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,4HD1Z@91061|Bacilli,26QEA@186822|Paenibacillaceae	91061|Bacilli	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
HKD2_k127_3706604_3	1403313.AXBR01000021_gene3087	7.956e-34	130.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,1ZAR2@1386|Bacillus	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
HKD2_k127_3706604_0	1403313.AXBR01000021_gene3088	0.0	1239.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
HKD2_k127_3706604_1	1403313.AXBR01000021_gene3089	8.588e-130	420.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,1ZBZ3@1386|Bacillus	91061|Bacilli	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HKD2_k127_3706604_2	796606.BMMGA3_06060	7.636e-118	379.0	COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,4HA2J@91061|Bacilli,1ZCHE@1386|Bacillus	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU16100	CoA_binding,Ligase_CoA
HKD2_k127_3707450_4	1403313.AXBR01000022_gene2722	6.178e-58	207.0	COG3594@1|root,COG3594@2|Bacteria,1TPGY@1239|Firmicutes,4HCER@91061|Bacilli,1ZDAV@1386|Bacillus	91061|Bacilli	G	COG3594 Fucose 4-O-acetylase and related acetyltransferases	ykrP	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD2_k127_3707450_6	1158604.I591_00983	9.179e-07	55.0	2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli,4B3V7@81852|Enterococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
HKD2_k127_3707450_0	1174504.AJTN02000234_gene3205	3.727e-304	939.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,4HA0Y@91061|Bacilli,1ZAU7@1386|Bacillus	91061|Bacilli	C	Fe-S oxidoreductase	bchE	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
HKD2_k127_3707450_1	1403313.AXBR01000022_gene2740	3.347e-196	620.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZD2H@1386|Bacillus	91061|Bacilli	P	COG0168 Trk-type K transport systems, membrane components	ktrD	-	-	-	-	-	-	-	-	-	-	-	TrkH
HKD2_k127_3707450_5	1403313.AXBR01000022_gene2741	2.043e-26	109.0	2BX75@1|root,32YR8@2|Bacteria,1VJMT@1239|Firmicutes,4HP70@91061|Bacilli,1ZIU2@1386|Bacillus	91061|Bacilli	S	small acid-soluble spore protein	sspD	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
HKD2_k127_3707450_3	1403313.AXBR01000022_gene2743	1.878e-59	221.0	2E3R1@1|root,32YNU@2|Bacteria,1VEND@1239|Firmicutes,4HNII@91061|Bacilli,1ZFAW@1386|Bacillus	91061|Bacilli	S	Anti-sigma factor N-terminus	rsgI	-	-	-	-	-	-	-	-	-	-	-	RsgI_N
HKD2_k127_3707450_2	1403313.AXBR01000022_gene2744	3.612e-93	311.0	COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,4HEBS@91061|Bacilli,1ZCY4@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigI	-	-	ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
HKD2_k127_3745222_0	1211114.ALIP01000104_gene957	7.193e-119	387.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1X33S@135614|Xanthomonadales	135614|Xanthomonadales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_3745222_3	1342301.JASD01000008_gene679	4.162e-24	111.0	COG2227@1|root,COG2227@2|Bacteria,1NB77@1224|Proteobacteria,2UARG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD2_k127_3745222_2	1047013.AQSP01000144_gene861	6.82e-38	157.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
HKD2_k127_3745222_4	504728.K649_04110	4.758e-16	79.0	COG2445@1|root,COG2445@2|Bacteria,1WK62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
HKD2_k127_3793236_1	1294265.JCM21738_2530	1.169e-182	575.0	COG0438@1|root,COG0438@2|Bacteria,1URQU@1239|Firmicutes,4HC5Z@91061|Bacilli,1ZCV3@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD2_k127_3793236_2	1117379.BABA_02984	3.322e-131	429.0	COG0515@1|root,COG0515@2|Bacteria,1VBSJ@1239|Firmicutes,4HKRP@91061|Bacilli,1ZBIH@1386|Bacillus	91061|Bacilli	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3793236_3	1131730.BAVI_14314	6.176e-39	152.0	COG1714@1|root,COG1714@2|Bacteria,1VIH4@1239|Firmicutes,4HSGI@91061|Bacilli,1ZF2E@1386|Bacillus	91061|Bacilli	S	membrane protein domain	yxaI	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD2_k127_3793236_0	1174504.AJTN02000004_gene2471	0.0	1386.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HKD2_k127_3796178_0	1403313.AXBR01000009_gene779	4.739e-160	515.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,1ZAWN@1386|Bacillus	91061|Bacilli	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD2_k127_3796415_0	1169144.KB910956_gene4134	9.668e-221	689.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD2_k127_3796415_1	574376.BAMA_12025	6.307e-132	424.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus	91061|Bacilli	L	hydrolase, TatD	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HKD2_k127_3855452_4	1340434.AXVA01000003_gene2020	3.575e-40	154.0	2D5FM@1|root,32TJ0@2|Bacteria,1VC6G@1239|Firmicutes,4HKFH@91061|Bacilli,1ZHDG@1386|Bacillus	91061|Bacilli	S	polyhydroxyalkanoic acid inclusion protein PhaP	phaP	-	-	-	-	-	-	-	-	-	-	-	PhaP_Bmeg
HKD2_k127_3855452_3	1460634.JCM19037_3956	3.355e-52	187.0	COG1695@1|root,COG1695@2|Bacteria,1V7D3@1239|Firmicutes,4HINI@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	phaQ	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD2_k127_3855452_5	1340434.AXVA01000003_gene2022	1.165e-33	135.0	2DSEU@1|root,33FV9@2|Bacteria,1VCU2@1239|Firmicutes,4HPZM@91061|Bacilli,1ZGVC@1386|Bacillus	91061|Bacilli	S	polyhydroxyalkanoic acid synthase, PhaR subunit	phaR	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
HKD2_k127_3855452_1	1340434.AXVA01000003_gene2023	7.668e-109	357.0	COG1028@1|root,COG1028@2|Bacteria,1UZB2@1239|Firmicutes,4HA42@91061|Bacilli,1ZDHI@1386|Bacillus	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
HKD2_k127_3855452_0	1340434.AXVA01000003_gene2024	3.792e-177	560.0	COG3243@1|root,COG3243@2|Bacteria,1V0SA@1239|Firmicutes,4HCRB@91061|Bacilli,1ZAX8@1386|Bacillus	91061|Bacilli	I	Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD2_k127_3855452_2	1160707.AJIK01000029_gene1620	2.301e-62	222.0	COG2267@1|root,COG2267@2|Bacteria,1UWXW@1239|Firmicutes,4HDPP@91061|Bacilli,26II4@186818|Planococcaceae	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
HKD2_k127_3878324_2	1403313.AXBR01000026_gene5148	8.385e-136	439.0	COG1316@1|root,COG1316@2|Bacteria,1TQ9C@1239|Firmicutes,4HB29@91061|Bacilli,1ZB6K@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ywtF_2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD2_k127_3878324_0	1403313.AXBR01000026_gene5149	6.171e-161	513.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,1ZBZB@1386|Bacillus	91061|Bacilli	M	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
HKD2_k127_3878324_1	1403313.AXBR01000026_gene5155	1.545e-136	437.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli,1ZC6D@1386|Bacillus	91061|Bacilli	GM	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system	tagH	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0015921,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1901264,GO:1901505	3.6.3.40	ko:K09693	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.104	-	-	ABC_tran,LysM
HKD2_k127_3878324_3	1403313.AXBR01000026_gene5156	7.28e-126	407.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,4HB9R@91061|Bacilli,1ZC4D@1386|Bacillus	91061|Bacilli	GM	Transport permease protein	tagG	GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0033036,GO:0051179,GO:0051234,GO:0071702,GO:1901264	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
HKD2_k127_3878324_4	1403313.AXBR01000026_gene5157	5.622e-08	55.0	COG1887@1|root,COG1887@2|Bacteria,1TP75@1239|Firmicutes,4H9Q1@91061|Bacilli,1ZB61@1386|Bacillus	91061|Bacilli	M	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	tagF	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glyphos_transf
HKD2_k127_3925540_5	1340434.AXVA01000010_gene5484	3.583e-06	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3925540_0	1174504.AJTN02000233_gene2554	5.941e-283	886.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4HBAG@91061|Bacilli,1ZBRW@1386|Bacillus	91061|Bacilli	D	Cell division protein FtsA	ftsA_1	-	-	-	-	-	-	-	-	-	-	-	FtsA,PilM_2
HKD2_k127_3925540_2	1403313.AXBR01000010_gene958	2.112e-199	624.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,1ZB0X@1386|Bacillus	91061|Bacilli	E	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate	aroA	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD2_k127_3925540_4	1385514.N782_03495	1.612e-06	50.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_3925540_3	1403313.AXBR01000010_gene957	2.723e-170	540.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,1ZCFZ@1386|Bacillus	91061|Bacilli	K	catabolite control protein A	ccpA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HKD2_k127_3925540_1	1403313.AXBR01000010_gene956	2.022e-208	652.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus	91061|Bacilli	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	iYO844.BSU29710	Hist_deacetyl
HKD2_k127_3947034_1	1449343.JQLQ01000002_gene910	2.375e-60	211.0	COG2128@1|root,COG2128@2|Bacteria,1VAK9@1239|Firmicutes,4HQMH@91061|Bacilli	91061|Bacilli	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD2_k127_3947034_2	935836.JAEL01000013_gene4542	3.798e-60	211.0	28NEG@1|root,32W71@2|Bacteria,1VAPN@1239|Firmicutes,4HQ5K@91061|Bacilli,1ZRE2@1386|Bacillus	91061|Bacilli	S	Staygreen protein	-	-	-	-	-	-	-	-	-	-	-	-	Staygreen
HKD2_k127_3947034_0	44251.PDUR_27270	2.112e-163	523.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HF7X@91061|Bacilli,26QF7@186822|Paenibacillaceae	91061|Bacilli	T	5TMR of 5TMR-LYT	-	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA
HKD2_k127_4000241_3	1403313.AXBR01000003_gene3962	5.209e-310	952.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,1ZB6Z@1386|Bacillus	91061|Bacilli	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HKD2_k127_4000241_4	1403313.AXBR01000003_gene3963	2.286e-203	656.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus	91061|Bacilli	E	COG1305 Transglutaminase-like enzymes	yebA	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
HKD2_k127_4000241_8	1174504.AJTN02000003_gene2111	7.083e-82	286.0	COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,1ZCAS@1386|Bacillus	91061|Bacilli	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	yeaD	-	-	-	-	-	-	-	-	-	-	-	DUF58
HKD2_k127_4000241_5	1403313.AXBR01000003_gene3965	2.786e-157	501.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZDJ1@1386|Bacillus	91061|Bacilli	S	COG0714 MoxR-like ATPases	yeaC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD2_k127_4000241_0	1227360.C176_05657	0.0	1260.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,26D5K@186818|Planococcaceae	91061|Bacilli	P	COG0474 Cation transport ATPase	yoaB	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD2_k127_4000241_2	1403313.AXBR01000004_gene1614	3.356e-319	980.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,1ZBKJ@1386|Bacillus	91061|Bacilli	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD2_k127_4000241_10	1403313.AXBR01000004_gene1615	3.553e-51	183.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,1ZGZ1@1386|Bacillus	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD2_k127_4000241_7	1403313.AXBR01000004_gene1616	6.363e-85	287.0	COG1266@1|root,COG1266@2|Bacteria,1V7N7@1239|Firmicutes,4HI4E@91061|Bacilli,1ZRP1@1386|Bacillus	91061|Bacilli	S	metal-dependent membrane protease	ydiL	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD2_k127_4000241_11	1403313.AXBR01000004_gene1617	3.533e-27	111.0	28VF7@1|root,2ZHHS@2|Bacteria,1W30J@1239|Firmicutes,4I07C@91061|Bacilli,1ZJ43@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4305
HKD2_k127_4000241_6	1174504.AJTN02000261_gene562	2.18e-111	362.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,1ZANM@1386|Bacillus	91061|Bacilli	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HKD2_k127_4000241_1	1403313.AXBR01000004_gene1620	0.0	1060.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD2_k127_4000241_9	666686.B1NLA3E_02430	2.284e-72	251.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
HKD2_k127_400795_1	1403313.AXBR01000005_gene2008	1.956e-117	385.0	COG0492@1|root,COG0492@2|Bacteria,1TSQS@1239|Firmicutes,4HC5G@91061|Bacilli,1ZB58@1386|Bacillus	91061|Bacilli	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
HKD2_k127_400795_2	1121091.AUMP01000020_gene3714	2.19e-76	260.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli	91061|Bacilli	I	Acyl-CoA hydrolase	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
HKD2_k127_400795_0	1123284.KB899044_gene539	2.2e-168	538.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli	91061|Bacilli	P	cation transport ATPase	pacL	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD2_k127_4155653_0	1403313.AXBR01000021_gene3175	1.572e-248	775.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus	91061|Bacilli	M	Penicillin-binding Protein	pbpX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD2_k127_4155653_2	1403313.AXBR01000021_gene3176	2.353e-38	146.0	COG4839@1|root,COG4839@2|Bacteria,1VDUV@1239|Firmicutes,4HKM7@91061|Bacilli,1ZIVC@1386|Bacillus	91061|Bacilli	D	Essential cell division protein	ftsL	-	-	-	-	-	-	-	-	-	-	-	DivIC
HKD2_k127_4155653_1	1403313.AXBR01000021_gene3177	6.581e-161	509.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,1ZCHN@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD2_k127_4155653_3	1403313.AXBR01000021_gene3178	3.637e-35	134.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,1ZFN0@1386|Bacillus	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HKD2_k127_4156237_0	504472.Slin_4251	2.549e-10	66.0	2CH0Y@1|root,32S8V@2|Bacteria,4NSPM@976|Bacteroidetes,47RDF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4156237_1	1247024.JRLH01000008_gene1540	1.616e-06	60.0	COG2755@1|root,COG2755@2|Bacteria,1NVG5@1224|Proteobacteria,1S15J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4156237_2	1247024.JRLH01000008_gene1540	5.121e-06	58.0	COG2755@1|root,COG2755@2|Bacteria,1NVG5@1224|Proteobacteria,1S15J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4162792_0	1403313.AXBR01000002_gene4396	0.0	1203.0	COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus	91061|Bacilli	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,TPR_8
HKD2_k127_4162792_1	1305836.AXVE01000015_gene3009	1.563e-88	297.0	COG2323@1|root,COG2323@2|Bacteria,1V1AI@1239|Firmicutes,4HDBF@91061|Bacilli,26EVK@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD2_k127_4162792_3	1403313.AXBR01000002_gene4384	2.98e-46	175.0	29XQF@1|root,30JG4@2|Bacteria,1TZDG@1239|Firmicutes,4I8MN@91061|Bacilli,1ZKNV@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4162792_2	1243664.CAVL020000016_gene2040	7.452e-51	181.0	COG0526@1|root,COG0526@2|Bacteria,1VA84@1239|Firmicutes,4HKCD@91061|Bacilli,1ZHXM@1386|Bacillus	91061|Bacilli	CO	Thioredoxin	ydbP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD2_k127_4166528_2	1403313.AXBR01000023_gene2678	1.141e-94	314.0	COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,4HGDN@91061|Bacilli,1ZBT2@1386|Bacillus	91061|Bacilli	S	B3/4 domain	yhzB	-	-	-	-	-	-	-	-	-	-	-	B3_4
HKD2_k127_4166528_3	1462527.CCDM010000002_gene685	1.079e-08	58.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4166528_4	1385514.N782_03495	3.08e-07	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4166528_0	1134413.ANNK01000090_gene143	8.14e-147	468.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,1ZBN8@1386|Bacillus	91061|Bacilli	S	HAD-hyrolase-like	ysaA	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD2_k127_4166528_1	1340434.AXVA01000003_gene2019	5.668e-111	362.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1ZBHS@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD2_k127_4179353_1	574375.BAGA_22525	9.639e-139	442.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus	91061|Bacilli	C	isocitrate	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD2_k127_4179353_0	1169144.KB910962_gene3008	1.296e-175	553.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZC27@1386|Bacillus	91061|Bacilli	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HKD2_k127_4179353_2	574375.BAGA_04455	2.255e-134	430.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,1ZBGS@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_4179353_3	1382358.JHVN01000020_gene1393	5.124e-93	316.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,21V7Q@150247|Anoxybacillus	91061|Bacilli	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
HKD2_k127_4189759_3	1403313.AXBR01000004_gene1624	1.974e-70	240.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,1ZGBU@1386|Bacillus	91061|Bacilli	S	ATPase or kinase	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD2_k127_4189759_2	1403313.AXBR01000004_gene1623	4.092e-116	377.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,1ZC43@1386|Bacillus	91061|Bacilli	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD2_k127_4189759_4	1460635.JCM19038_3966	3.779e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
HKD2_k127_4189759_0	1174504.AJTN02000261_gene559	2.646e-189	594.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,1ZBT3@1386|Bacillus	91061|Bacilli	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD2_k127_4189759_1	1499680.CCFE01000023_gene2490	1.17e-119	400.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
HKD2_k127_41969_6	1469948.JPNB01000001_gene1204	3.474e-61	218.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,36GH1@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD2_k127_41969_8	1122915.AUGY01000174_gene4168	6.341e-27	111.0	2DNDD@1|root,32WXK@2|Bacteria,1VA1A@1239|Firmicutes,4HM40@91061|Bacilli,272MI@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_41969_7	1122915.AUGY01000174_gene4168	1.621e-35	136.0	2DNDD@1|root,32WXK@2|Bacteria,1VA1A@1239|Firmicutes,4HM40@91061|Bacilli,272MI@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_41969_4	1132442.KB889752_gene963	8.023e-69	236.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,1ZHDQ@1386|Bacillus	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
HKD2_k127_41969_0	1403313.AXBR01000017_gene3652	9.69e-190	601.0	COG2244@1|root,COG2244@2|Bacteria,1VRYZ@1239|Firmicutes,4HV8Z@91061|Bacilli,1ZCGG@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	ykvU	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_C
HKD2_k127_41969_3	714961.BFZC1_10582	4.422e-74	254.0	2C5T7@1|root,32VPK@2|Bacteria,1VASY@1239|Firmicutes,4HMXX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_41969_2	1295642.H839_05294	6.334e-76	257.0	COG0791@1|root,COG0791@2|Bacteria,1VX13@1239|Firmicutes,4HX2B@91061|Bacilli,1WHCE@129337|Geobacillus	91061|Bacilli	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HKD2_k127_41969_1	1536773.R70331_14030	1.967e-88	300.0	COG0596@1|root,COG0596@2|Bacteria,1UYIN@1239|Firmicutes,4HEY9@91061|Bacilli,26QGH@186822|Paenibacillaceae	91061|Bacilli	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD2_k127_41969_5	1450694.BTS2_1180	4.966e-66	232.0	COG1309@1|root,COG1309@2|Bacteria,1V1ZJ@1239|Firmicutes,4IK6T@91061|Bacilli,1ZFGB@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_4222646_0	1403313.AXBR01000002_gene4148	1.272e-192	604.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus	91061|Bacilli	E	Aminotransferase	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_4222646_2	1403313.AXBR01000022_gene2836	1.031e-159	506.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	ssuB	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_4222646_3	1403313.AXBR01000022_gene2835	3.088e-120	390.0	COG0600@1|root,COG0600@2|Bacteria,1TR9N@1239|Firmicutes,4HC2U@91061|Bacilli,1ZQFP@1386|Bacillus	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	ssuC_2	-	-	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	BPD_transp_1
HKD2_k127_4222646_1	1403313.AXBR01000022_gene2834	5.723e-173	547.0	COG0715@1|root,COG0715@2|Bacteria,1TRT8@1239|Firmicutes,4HCK6@91061|Bacilli,1ZB5K@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	ssuA	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
HKD2_k127_4222646_4	1294265.JCM21738_1172	2.471e-51	183.0	COG0741@1|root,COG0741@2|Bacteria,1VD4A@1239|Firmicutes,4HN7R@91061|Bacilli,1ZDE7@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yocA	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
HKD2_k127_4230298_7	997296.PB1_07072	2.569e-45	165.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,1ZH0F@1386|Bacillus	91061|Bacilli	K	COG2002 Regulators of stationary sporulation gene expression	abrB	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
HKD2_k127_4230298_3	1403313.AXBR01000030_gene5385	7.613e-161	509.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus	91061|Bacilli	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD2_k127_4230298_8	1196029.ALIM01000036_gene1069	5.126e-26	110.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,1ZIXI@1386|Bacillus	91061|Bacilli	L	endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD2_k127_4230298_4	1403313.AXBR01000030_gene5387	7.842e-138	441.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus	91061|Bacilli	S	Conserved hypothetical protein 95	yabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.223	ko:K07461,ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GIY-YIG,MTS
HKD2_k127_4230298_6	1174504.AJTN02000203_gene2794	4.171e-50	181.0	COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,1ZGZH@1386|Bacillus	91061|Bacilli	L	Involved in initiation control of chromosome replication	yabA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	YabB
HKD2_k127_4230298_1	1403313.AXBR01000030_gene5389	1.41e-168	531.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli,1ZBCK@1386|Bacillus	91061|Bacilli	S	stage 0 sporulation protein	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	PSP1
HKD2_k127_4230298_2	1403313.AXBR01000030_gene5390	7.009e-165	523.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,1ZBDA@1386|Bacillus	91061|Bacilli	L	DNA polymerase III	holB	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
HKD2_k127_4230298_5	1403313.AXBR01000030_gene5393	2.79e-93	310.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,1ZBSZ@1386|Bacillus	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
HKD2_k127_4230298_0	1403313.AXBR01000030_gene5394	8.057e-188	598.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus	91061|Bacilli	E	Orn Lys Arg decarboxylase	yaaO	-	-	-	-	-	-	-	-	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD2_k127_4230298_9	1403313.AXBR01000030_gene5395	4.482e-24	101.0	2EIS2@1|root,33CHE@2|Bacteria,1VM34@1239|Firmicutes,4HR6Z@91061|Bacilli,1ZK09@1386|Bacillus	91061|Bacilli	S	Inhibitor of sigma-G Gin	csfB	-	-	-	-	-	-	-	-	-	-	-	Gin
HKD2_k127_4253306_2	1408424.JHYI01000001_gene2051	2.448e-23	99.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,4HKDP@91061|Bacilli,1ZHVQ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0296 family	ylzA	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HKD2_k127_4253306_0	1122947.FR7_3262	1.154e-143	460.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4H2DA@909932|Negativicutes	909932|Negativicutes	S	TIGR00255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD2_k127_4253306_1	1122947.FR7_3261	9.858e-28	114.0	2D5XH@1|root,32TK0@2|Bacteria,1VBUI@1239|Firmicutes,4H55H@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4254259_2	1403313.AXBR01000013_gene1509	3.003e-134	431.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,1ZD80@1386|Bacillus	91061|Bacilli	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD2_k127_4254259_7	1340434.AXVA01000010_gene5484	5.492e-06	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4254259_3	1395513.P343_04755	1.437e-131	430.0	COG0477@1|root,COG2814@2|Bacteria,1TQKU@1239|Firmicutes,4HA5Q@91061|Bacilli	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	yybF1	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
HKD2_k127_4254259_4	1403313.AXBR01000013_gene1529	1.846e-96	323.0	COG1309@1|root,COG1309@2|Bacteria,1TP0U@1239|Firmicutes,4HE9Q@91061|Bacilli,1ZBMJ@1386|Bacillus	91061|Bacilli	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_4254259_1	1403313.AXBR01000010_gene1176	3.217e-215	678.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_4254259_5	1243664.CAVL020000019_gene3598	5.584e-59	207.0	COG0322@1|root,COG0322@2|Bacteria,1V8E6@1239|Firmicutes,4HJHV@91061|Bacilli,1ZGGU@1386|Bacillus	91061|Bacilli	L	COG0322 Nuclease subunit of the excinuclease complex	yurQ	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	-	-	-	-	-	-	-	-	-	GIY-YIG
HKD2_k127_4254259_0	796606.BMMGA3_09065	7.894e-289	904.0	COG0840@1|root,COG0840@2|Bacteria,1TRC5@1239|Firmicutes,4HTVX@91061|Bacilli,1ZM39@1386|Bacillus	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
HKD2_k127_4254259_6	1408303.JNJJ01000021_gene4942	6.443e-44	164.0	COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,1ZB5G@1386|Bacillus	91061|Bacilli	E	Proline dehydrogenase	fadM	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD2_k127_4255577_7	1403313.AXBR01000005_gene1816	1.953e-58	205.0	2F172@1|root,33U86@2|Bacteria,1VUP5@1239|Firmicutes,4HVPB@91061|Bacilli,1ZH8W@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4255577_5	1117379.BABA_20866	2.039e-132	425.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,1ZAS3@1386|Bacillus	91061|Bacilli	L	exodeoxyribonuclease III	exoA	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD2_k127_4255577_1	1403313.AXBR01000005_gene1820	4.778e-251	780.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus	91061|Bacilli	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HKD2_k127_4255577_3	1403313.AXBR01000005_gene1821	5.006e-183	578.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,1ZBVM@1386|Bacillus	91061|Bacilli	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD2_k127_4255577_2	1403313.AXBR01000005_gene1822	6.372e-211	659.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,1ZCF2@1386|Bacillus	91061|Bacilli	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD2_k127_4255577_0	1089548.KI783301_gene1967	3.23e-252	794.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli	91061|Bacilli	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HKD2_k127_4255577_4	1033734.CAET01000016_gene4060	5.645e-177	558.0	COG3387@1|root,COG3387@2|Bacteria,1V0CI@1239|Firmicutes,4HCZU@91061|Bacilli,1ZD6W@1386|Bacillus	91061|Bacilli	G	Glycosyl hydrolases family 15	-	-	-	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_15
HKD2_k127_4255577_6	935836.JAEL01000006_gene2842	7.19e-68	240.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
HKD2_k127_4256708_1	1461580.CCAS010000068_gene4050	5.329e-180	565.0	COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,4HBEX@91061|Bacilli,1ZBHT@1386|Bacillus	91061|Bacilli	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	cysI	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HKD2_k127_4256708_0	997296.PB1_02455	5.534e-313	968.0	COG0369@1|root,COG0369@2|Bacteria,1TP5J@1239|Firmicutes,4HCQI@91061|Bacilli,1ZANY@1386|Bacillus	91061|Bacilli	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU33440	FAD_binding_1,Flavodoxin_1,NAD_binding_1
HKD2_k127_4256708_2	997296.PB1_02460	8.488e-163	515.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,1ZBIX@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	cysL	-	-	ko:K21900	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HKD2_k127_4256708_8	1340434.AXVA01000010_gene5484	5.206e-06	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4256708_4	395494.Galf_0920	3.126e-108	364.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,44VG5@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD2_k127_4256708_3	1117379.BABA_02187	1.086e-116	382.0	COG0679@1|root,COG0679@2|Bacteria,1V0ZS@1239|Firmicutes,4HFI1@91061|Bacilli,1ZDFZ@1386|Bacillus	91061|Bacilli	S	Membrane transport protein	XK27_04815	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HKD2_k127_4256708_6	997296.PB1_03855	1.339e-62	220.0	2ES56@1|root,33JPZ@2|Bacteria,1U2H0@1239|Firmicutes,4IM8G@91061|Bacilli,1ZJGI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4256708_7	1499680.CCFE01000033_gene3947	1.822e-18	85.0	COG4877@1|root,COG4877@2|Bacteria,1VEY1@1239|Firmicutes,4HNMN@91061|Bacilli,1ZJ24@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Arc,HicB,RHH_5
HKD2_k127_4256708_5	666686.B1NLA3E_00865	3.177e-98	322.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,4HA6G@91061|Bacilli,1ZD7J@1386|Bacillus	91061|Bacilli	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD2_k127_4257335_2	1403313.AXBR01000023_gene2361	7.187e-123	402.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	malR	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
HKD2_k127_4257335_1	1403313.AXBR01000023_gene2363	6.001e-178	571.0	COG0366@1|root,COG0366@2|Bacteria,1TSVI@1239|Firmicutes,4HCV2@91061|Bacilli,1ZDR6@1386|Bacillus	91061|Bacilli	G	Alpha amylase, catalytic domain	amyA	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
HKD2_k127_4257335_0	1403313.AXBR01000023_gene2365	1.701e-277	863.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus	91061|Bacilli	G	Alpha amylase, N-terminal ig-like domain	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N,Malt_amylase_C
HKD2_k127_4257335_3	1340434.AXVA01000010_gene5484	4.933e-06	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4266325_0	1307436.PBF_01435	6.465e-164	526.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA
HKD2_k127_4266325_1	1484479.DI14_13320	1.465e-56	214.0	COG0265@1|root,COG0265@2|Bacteria,1UZ8K@1239|Firmicutes,4HPBV@91061|Bacilli	91061|Bacilli	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
HKD2_k127_4390281_1	997296.PB1_03860	9.309e-202	633.0	COG3733@1|root,COG3733@2|Bacteria,1TY2K@1239|Firmicutes,4I75Q@91061|Bacilli,1ZC7C@1386|Bacillus	91061|Bacilli	Q	Copper amine oxidase, enzyme domain	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
HKD2_k127_4390281_2	666686.B1NLA3E_18975	2.012e-66	235.0	COG2207@1|root,COG2207@2|Bacteria,1V3PR@1239|Firmicutes,4IR30@91061|Bacilli,1ZRR7@1386|Bacillus	1239|Firmicutes	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD2_k127_4390281_0	1403313.AXBR01000009_gene782	0.0	1174.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD2_k127_440273_2	1174504.AJTN02000174_gene3957	7.239e-155	492.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZAR0@1386|Bacillus	91061|Bacilli	E	Arginine	speA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	4.1.1.17,4.1.1.19	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00133,M00134	R00566,R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD2_k127_440273_1	1403313.AXBR01000021_gene3240	1.055e-177	559.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBRG@1386|Bacillus	91061|Bacilli	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	fabK	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
HKD2_k127_440273_6	1174504.AJTN02000174_gene3955	2.673e-36	138.0	COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,1ZHT9@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0223 family	yktA	-	-	-	-	-	-	-	-	-	-	-	UPF0223
HKD2_k127_440273_0	1403313.AXBR01000021_gene3237	5.539e-221	694.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus	91061|Bacilli	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD2_k127_440273_4	1403313.AXBR01000021_gene3236	4.593e-96	317.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,1ZBB7@1386|Bacillus	91061|Bacilli	EH	Anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD2_k127_440273_7	1385514.N782_03495	7.482e-07	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_440273_3	1403313.AXBR01000021_gene3235	1.106e-151	486.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
HKD2_k127_440273_5	1403313.AXBR01000021_gene3234	1.034e-79	269.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,1ZD63@1386|Bacillus	91061|Bacilli	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HKD2_k127_4429781_5	1403313.AXBR01000026_gene5166	6.735e-22	97.0	COG0653@1|root,COG0653@2|Bacteria,1TSCF@1239|Firmicutes,4HBNY@91061|Bacilli,1ZD65@1386|Bacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0022804,GO:0022857,GO:0022884,GO:0032940,GO:0033036,GO:0042886,GO:0042887,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD2_k127_4429781_2	1307436.PBF_07888	3.848e-102	340.0	2BYTC@1|root,2Z9IH@2|Bacteria,1TSAA@1239|Firmicutes,4HCVE@91061|Bacilli,1ZBVB@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4429781_6	1340434.AXVA01000010_gene5484	1.675e-07	57.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4429781_3	796606.BMMGA3_15155	6.562e-54	192.0	2BRS2@1|root,32KRY@2|Bacteria,1V885@1239|Firmicutes,4HIYJ@91061|Bacilli,1ZH4A@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4429781_1	1403313.AXBR01000026_gene5163	4.617e-142	456.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4IQSP@91061|Bacilli,1ZRN9@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD2_k127_4429781_0	997296.PB1_08917	7.6e-143	473.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZDXZ@1386|Bacillus	91061|Bacilli	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Cu_amine_oxidN1,Peptidase_M14
HKD2_k127_4429781_4	1403313.AXBR01000026_gene5162	1.88e-45	166.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	cwlS	-	-	ko:K19223,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
HKD2_k127_4445551_2	1403313.AXBR01000007_gene387	8.595e-62	216.0	2EENU@1|root,338GN@2|Bacteria,1VK1A@1239|Firmicutes,4HNX3@91061|Bacilli,1ZC57@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2663)	ypbF	-	-	-	-	-	-	-	-	-	-	-	DUF2663
HKD2_k127_4445551_1	1403313.AXBR01000007_gene384	6.697e-82	276.0	COG4862@1|root,COG4862@2|Bacteria,1V1B7@1239|Firmicutes,4HBM5@91061|Bacilli,1ZF7G@1386|Bacillus	91061|Bacilli	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC	mecB	GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
HKD2_k127_4445551_0	1403313.AXBR01000007_gene383	2.587e-176	554.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gudB	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.2,1.4.1.4	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD2_k127_4461286_3	1403313.AXBR01000013_gene1457	2.629e-31	123.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	yumB	GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iYO844.BSU32100	Pyr_redox_2
HKD2_k127_4461286_0	1403313.AXBR01000013_gene1456	4.839e-180	567.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1ZCEZ@1386|Bacillus	91061|Bacilli	C	reductase	yumC	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	iYO844.BSU32110	Pyr_redox_2
HKD2_k127_4461286_2	1174504.AJTN02000200_gene3543	1.074e-58	205.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,1ZH92@1386|Bacillus	91061|Bacilli	S	Belongs to the HesB IscA family	yutM	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD2_k127_4461286_1	1243664.CAVL020000054_gene2971	5.182e-85	286.0	COG1655@1|root,COG1655@2|Bacteria,1UY0V@1239|Firmicutes,4HDH4@91061|Bacilli,1ZD58@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
HKD2_k127_447225_0	580340.Tlie_1478	8.796e-91	319.0	COG3959@1|root,COG3959@2|Bacteria,3TA23@508458|Synergistetes	508458|Synergistetes	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD2_k127_447225_1	1449126.JQKL01000014_gene2985	4.812e-90	305.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
HKD2_k127_4492144_2	1307436.PBF_16379	1.796e-74	260.0	COG0631@1|root,COG0631@2|Bacteria,1V9VA@1239|Firmicutes,4HJDH@91061|Bacilli,1ZG0X@1386|Bacillus	91061|Bacilli	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
HKD2_k127_4492144_1	574376.BAMA_03105	5.308e-81	276.0	COG2188@1|root,COG2188@2|Bacteria,1UYYY@1239|Firmicutes,4HHGX@91061|Bacilli,1ZCNI@1386|Bacillus	91061|Bacilli	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
HKD2_k127_4492144_0	697284.ERIC2_c20470	2.542e-108	360.0	COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,4HDKQ@91061|Bacilli	91061|Bacilli	M	Sugar isomerase, AgaS family	agaS	-	-	ko:K02082	-	-	-	-	ko00000,ko01000	-	-	-	SIS
HKD2_k127_452958_14	1294265.JCM21738_1787	3.72e-06	50.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD2_k127_452958_3	1403313.AXBR01000021_gene3026	1.878e-204	642.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,1ZC5R@1386|Bacillus	91061|Bacilli	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HKD2_k127_452958_10	634956.Geoth_2626	2.716e-90	300.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,1WF1K@129337|Geobacillus	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06365	CDP-OH_P_transf
HKD2_k127_452958_9	1403313.AXBR01000021_gene3028	5.59e-104	345.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1ZDC1@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
HKD2_k127_452958_5	1403313.AXBR01000021_gene3029	3.838e-147	470.0	28HGR@1|root,2Z7SI@2|Bacteria,1TRXV@1239|Firmicutes,4HA2I@91061|Bacilli,1ZAU1@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3388)	ymfK	-	-	-	-	-	-	-	-	-	-	-	DUF3388
HKD2_k127_452958_11	1403313.AXBR01000021_gene3030	1.466e-40	151.0	2E5KP@1|root,330BT@2|Bacteria,1VGM7@1239|Firmicutes,4HNNX@91061|Bacilli,1ZHTB@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3243)	ymfJ	-	-	-	-	-	-	-	-	-	-	-	DUF3243
HKD2_k127_452958_8	1403313.AXBR01000021_gene3031	2.948e-128	412.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,4HEU2@91061|Bacilli,1ZCIS@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HKD2_k127_452958_2	1403313.AXBR01000021_gene3032	2.532e-222	694.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,1ZBXQ@1386|Bacillus	91061|Bacilli	S	zinc protease	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD2_k127_452958_4	1403313.AXBR01000021_gene3033	3.104e-197	623.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,1ZCAJ@1386|Bacillus	91061|Bacilli	S	Peptidase M16	albE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
HKD2_k127_452958_6	1403313.AXBR01000021_gene3037	1.763e-146	472.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus	91061|Bacilli	S	ABC-type transport system, periplasmic component surface lipoprotein	tcsA	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
HKD2_k127_452958_12	1501230.ET33_11325	5.729e-32	126.0	2E4AM@1|root,32XKC@2|Bacteria,1VE9E@1239|Firmicutes,4HN07@91061|Bacilli,275TK@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_452958_0	1403313.AXBR01000021_gene3040	0.0	1152.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HKD2_k127_452958_7	1403313.AXBR01000021_gene3042	4.327e-130	418.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,4H9XG@91061|Bacilli,1ZBH5@1386|Bacillus	91061|Bacilli	OU	COG0740 Protease subunit of ATP-dependent Clp proteases	tepA	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
HKD2_k127_452958_1	1403313.AXBR01000021_gene3043	6.563e-293	905.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD2_k127_453431_0	649747.HMPREF0083_00313	7.76e-122	409.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9
HKD2_k127_453431_3	1121938.AUDY01000011_gene759	1.007e-26	115.0	2DN8F@1|root,32W3A@2|Bacteria,1VB6U@1239|Firmicutes,4HKBV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_453431_2	1042163.BRLA_c023010	1.754e-68	234.0	COG4319@1|root,COG4319@2|Bacteria,1V5V3@1239|Firmicutes,4HIZV@91061|Bacilli	91061|Bacilli	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
HKD2_k127_453431_1	1185653.A1A1_16453	5.805e-73	249.0	COG0494@1|root,COG0494@2|Bacteria,1V4B2@1239|Firmicutes,4HGZZ@91061|Bacilli,26FKH@186818|Planococcaceae	91061|Bacilli	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_45674_0	1403313.AXBR01000007_gene332	4.54e-140	449.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus	91061|Bacilli	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22430	Pantoate_transf
HKD2_k127_45674_1	1403313.AXBR01000007_gene331	2.116e-129	418.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,1ZAV5@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HKD2_k127_45674_2	1174504.AJTN02000249_gene798	2.506e-64	222.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,1ZG9V@1386|Bacillus	91061|Bacilli	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HKD2_k127_4569577_7	1403313.AXBR01000002_gene4108	3.96e-20	92.0	29NRW@1|root,309PW@2|Bacteria,1U5GK@1239|Firmicutes,4IF7D@91061|Bacilli,1ZIZN@1386|Bacillus	91061|Bacilli	S	YgaB-like protein	ygaB	-	-	-	-	-	-	-	-	-	-	-	YgaB
HKD2_k127_4569577_6	1174504.AJTN02000238_gene540	1.637e-103	337.0	COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,1ZB2J@1386|Bacillus	91061|Bacilli	J	Belongs to the UPF0374 family	ygaC	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
HKD2_k127_4569577_1	1174504.AJTN02000238_gene539	2.775e-297	919.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus	91061|Bacilli	V	ABC transporter	ygaD	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
HKD2_k127_4569577_0	1403313.AXBR01000002_gene4097	0.0	2494.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus	91061|Bacilli	E	glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD2_k127_4569577_2	1174504.AJTN02000238_gene536	3.058e-249	772.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HBDZ@91061|Bacilli,1ZB74@1386|Bacillus	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	gsaB	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU08710	Aminotran_3
HKD2_k127_4569577_3	1403313.AXBR01000002_gene4094	4.304e-188	591.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,1ZBGB@1386|Bacillus	91061|Bacilli	S	transport system, ATPase component	drrA1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_4569577_4	1403313.AXBR01000002_gene4093	7.803e-135	433.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,1ZBKH@1386|Bacillus	91061|Bacilli	S	ABC transporter (permease)	M1-956	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
HKD2_k127_4569577_5	1403313.AXBR01000002_gene4092	1.699e-131	422.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,1ZAWY@1386|Bacillus	91061|Bacilli	S	transport system, permease component	M1-957	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
HKD2_k127_4577578_0	1403313.AXBR01000008_gene655	0.0	1541.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD2_k127_4588920_2	1169144.KB910924_gene434	4.349e-23	98.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,4HKDP@91061|Bacilli,1ZHVQ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0296 family	ylzA	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HKD2_k127_4588920_0	1169144.KB910924_gene435	1.133e-123	404.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus	91061|Bacilli	S	stress-induced protein	yloC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD2_k127_4588920_1	574375.BAGA_00775	1.24e-57	202.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus	91061|Bacilli	P	COG0474 Cation transport ATPase	yloB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	iYO844.BSU15650	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD2_k127_4601333_2	1403313.AXBR01000013_gene1309	6.933e-11	63.0	COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,1ZC95@1386|Bacillus	91061|Bacilli	S	Putative adhesin	yvlB	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HKD2_k127_4601333_1	997296.PB1_09467	8.409e-75	258.0	COG0860@1|root,COG0860@2|Bacteria,1V4B9@1239|Firmicutes,4HGZ9@91061|Bacilli,1ZPVS@1386|Bacillus	91061|Bacilli	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1,SPOR
HKD2_k127_4601333_0	1403313.AXBR01000013_gene1310	2.762e-122	394.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,1ZD05@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HKD2_k127_4601871_11	1403313.AXBR01000007_gene454	1.208e-52	187.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD2_k127_4601871_14	1444306.JFZC01000047_gene393	1.536e-21	96.0	2DQ8S@1|root,335BX@2|Bacteria,1UIQX@1239|Firmicutes,4ISQU@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
HKD2_k127_4601871_10	1211814.CAPG01000093_gene4264	2.184e-59	208.0	COG1846@1|root,COG1846@2|Bacteria,1V73Z@1239|Firmicutes,4HIWP@91061|Bacilli,1ZFY6@1386|Bacillus	91061|Bacilli	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
HKD2_k127_4601871_16	1117379.BABA_12515	6.764e-08	59.0	29KSF@1|root,307PV@2|Bacteria,1U20D@1239|Firmicutes,4IBH8@91061|Bacilli,1ZGQZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4601871_12	1403313.AXBR01000007_gene456	7.439e-47	174.0	COG0789@1|root,COG0789@2|Bacteria,1VH5D@1239|Firmicutes,4HQ0J@91061|Bacilli,1ZG6F@1386|Bacillus	91061|Bacilli	K	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure	racA	-	-	ko:K11686	-	-	-	-	ko00000,ko03036	-	-	-	MerR_1
HKD2_k127_4601871_6	1403313.AXBR01000007_gene460	9.125e-132	424.0	COG1562@1|root,COG1562@2|Bacteria,1TRWV@1239|Firmicutes,4HAFU@91061|Bacilli,1ZD6E@1386|Bacillus	91061|Bacilli	I	Squalene/phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
HKD2_k127_4601871_3	1403313.AXBR01000007_gene461	8.498e-156	497.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus	91061|Bacilli	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
HKD2_k127_4601871_1	1403313.AXBR01000007_gene462	2.443e-256	797.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,1ZCZ3@1386|Bacillus	91061|Bacilli	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
HKD2_k127_4601871_7	1121091.AUMP01000003_gene2709	1.757e-113	368.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli	91061|Bacilli	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_4601871_8	935837.JAEK01000008_gene3438	1.543e-112	366.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,1ZCXP@1386|Bacillus	91061|Bacilli	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_4601871_0	665952.HMPREF1015_01123	1.271e-282	873.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZBHM@1386|Bacillus	91061|Bacilli	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	yngE	-	-	-	-	-	-	-	-	-	-	iYO844.BSU18210	Carboxyl_trans
HKD2_k127_4601871_5	1132442.KB889752_gene1039	1.329e-133	430.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	yngF	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD2_k127_4601871_4	345219.Bcoa_1873	6.579e-136	438.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1ZC18@1386|Bacillus	91061|Bacilli	E	Hydroxymethylglutaryl-CoA lyase	yngG	GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD2_k127_4601871_13	345219.Bcoa_1872	2.529e-23	100.0	COG0511@1|root,COG0511@2|Bacteria,1UI6N@1239|Firmicutes,4ISFM@91061|Bacilli,1ZIUY@1386|Bacillus	91061|Bacilli	I	Biotin carboxyl carrier protein	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD2_k127_4601871_2	345219.Bcoa_1871	7.768e-231	721.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus	91061|Bacilli	I	Biotin carboxylase	yngH	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD2_k127_4601871_9	1382358.JHVN01000026_gene469	6.217e-92	303.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,21WKI@150247|Anoxybacillus	91061|Bacilli	IQ	AMP-binding enzyme	yngI	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_4640576_2	1174504.AJTN02000010_gene4493	5.595e-41	160.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	cwlS	-	-	ko:K19223,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
HKD2_k127_4640576_0	1305836.AXVE01000011_gene750	9.605e-161	526.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,26F0S@186818|Planococcaceae	91061|Bacilli	M	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FlgD_ig,Peptidase_S8,SLH
HKD2_k127_4640576_1	1347086.CCBA010000004_gene4234	1.135e-89	312.0	COG4193@1|root,COG4733@1|root,COG4193@2|Bacteria,COG4733@2|Bacteria,1V1F9@1239|Firmicutes,4HWI1@91061|Bacilli,1ZRF0@1386|Bacillus	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	lytD	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,PA14,SH3_3,SH3_8,SPOR
HKD2_k127_4653011_5	189425.PGRAT_01910	9.885e-69	239.0	COG4132@1|root,COG4132@2|Bacteria,1TRF0@1239|Firmicutes,4HCV5@91061|Bacilli,26UB1@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
HKD2_k127_4653011_3	1347368.HG964403_gene4122	4.282e-110	361.0	COG1177@1|root,COG1177@2|Bacteria,1V0UU@1239|Firmicutes,4HD56@91061|Bacilli,1ZF0W@1386|Bacillus	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
HKD2_k127_4653011_1	1347368.HG964403_gene4123	7.661e-131	427.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,1ZC8R@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
HKD2_k127_4653011_4	1145276.T479_05545	1.892e-79	273.0	COG1349@1|root,COG1349@2|Bacteria,1U2B1@1239|Firmicutes,4IQMQ@91061|Bacilli,3IVSS@400634|Lysinibacillus	91061|Bacilli	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HKD2_k127_4653011_0	1145276.T479_05550	9.761e-137	442.0	COG1387@1|root,COG1387@2|Bacteria,1UZ0M@1239|Firmicutes,4HAUH@91061|Bacilli,3IWW8@400634|Lysinibacillus	91061|Bacilli	E	COG1387 Histidinol phosphatase and related hydrolases of the PHP family	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HKD2_k127_4653011_2	1034347.CAHJ01000049_gene383	3.966e-111	363.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,1ZB38@1386|Bacillus	91061|Bacilli	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD2_k127_466769_0	1285586.H131_21662	2.328e-157	501.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3IZ23@400634|Lysinibacillus	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	cysK5	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD2_k127_466769_2	1034347.CAHJ01000011_gene2239	1.155e-15	79.0	2ECS3@1|root,336PR@2|Bacteria,1VFZI@1239|Firmicutes,4HPGS@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_466769_3	1347369.CCAD010000039_gene640	4.475e-08	55.0	29REB@1|root,30CGW@2|Bacteria,1U9VZ@1239|Firmicutes,4IK3R@91061|Bacilli,1ZKD9@1386|Bacillus	91061|Bacilli	S	SR1 protein	-	-	-	-	-	-	-	-	-	-	-	-	SR1P
HKD2_k127_466769_1	1403313.AXBR01000021_gene3241	8.139e-107	349.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZAR0@1386|Bacillus	91061|Bacilli	E	Arginine	speA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	4.1.1.17,4.1.1.19	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00133,M00134	R00566,R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD2_k127_4668839_5	1403313.AXBR01000010_gene944	6.779e-135	433.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,1ZBZY@1386|Bacillus	91061|Bacilli	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
HKD2_k127_4668839_4	1403313.AXBR01000010_gene945	2.162e-180	571.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,1ZBHY@1386|Bacillus	91061|Bacilli	E	Cysteine desulfurase	iscS2	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD2_k127_4668839_2	1403313.AXBR01000010_gene946	5.699e-236	741.0	COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,1ZAWX@1386|Bacillus	91061|Bacilli	D	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization	ezrA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	-	ko:K06286	-	-	-	-	ko00000,ko03036	-	-	-	EzrA
HKD2_k127_4668839_6	1403313.AXBR01000010_gene947	5.321e-132	425.0	COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,4H9P1@91061|Bacilli,1ZCA3@1386|Bacillus	91061|Bacilli	E	COG1387 Histidinol phosphatase and related hydrolases of the PHP family	hisK	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
HKD2_k127_4668839_8	1403313.AXBR01000010_gene948	2.039e-100	331.0	COG1309@1|root,COG1309@2|Bacteria,1V6TA@1239|Firmicutes,4HISQ@91061|Bacilli,1ZGRH@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yttP	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_4668839_9	1034347.CAHJ01000040_gene4549	2.638e-72	246.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,1ZFMG@1386|Bacillus	91061|Bacilli	T	GAF domain-containing protein	ytsP	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
HKD2_k127_4668839_3	1174504.AJTN02000233_gene2586	5.145e-209	666.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus	91061|Bacilli	T	COG2199 FOG GGDEF domain	ytrP	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
HKD2_k127_4668839_7	1347369.CCAD010000063_gene3973	3.805e-114	370.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,1ZCEB@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD2_k127_4668839_1	1403313.AXBR01000010_gene951	1.957e-250	775.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD2_k127_4668839_0	1403313.AXBR01000010_gene952	0.0	1137.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus	91061|Bacilli	M	COG0744 Membrane carboxypeptidase (penicillin-binding protein)	pbp1B	-	2.4.1.129	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD2_k127_4669186_3	796606.BMMGA3_01005	1.492e-113	371.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,1ZBIU@1386|Bacillus	91061|Bacilli	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HKD2_k127_4669186_2	1403313.AXBR01000025_gene4928	4.137e-147	477.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
HKD2_k127_4669186_1	1403313.AXBR01000025_gene4927	7.008e-261	807.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,1ZC74@1386|Bacillus	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD2_k127_4669186_0	1403313.AXBR01000025_gene4925	0.0	1058.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus	91061|Bacilli	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iSB619.SA_RS11245,iYO844.BSU01780	GATase_6,SIS
HKD2_k127_4671970_0	1117379.BABA_02252	1.508e-246	764.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus	91061|Bacilli	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
HKD2_k127_4671970_1	1117379.BABA_02247	3.278e-58	205.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,4HM9M@91061|Bacilli,1ZHC7@1386|Bacillus	91061|Bacilli	K	transcriptional	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892,ko:K22043	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HKD2_k127_4671970_2	1121091.AUMP01000044_gene3913	2.156e-29	128.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
HKD2_k127_4681758_1	1211814.CAPG01000064_gene3030	1.124e-64	221.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_4681758_2	1174504.AJTN02000194_gene4187	1.201e-46	174.0	COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,1ZH95@1386|Bacillus	91061|Bacilli	K	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling	rpoE	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	HARE-HTH
HKD2_k127_4681758_0	1174504.AJTN02000194_gene4186	8.526e-307	945.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,1ZB0S@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HKD2_k127_4681758_3	1340434.AXVA01000010_gene5484	3.745e-05	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4702655_2	1227360.C176_06297	8.894e-131	426.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAHF@91061|Bacilli,26EPJ@186818|Planococcaceae	91061|Bacilli	P	ATPases associated with a variety of cellular activities	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
HKD2_k127_4702655_4	1227360.C176_06302	4.733e-96	321.0	COG0619@1|root,COG0619@2|Bacteria,1V0B0@1239|Firmicutes,4HFP9@91061|Bacilli,26FK6@186818|Planococcaceae	91061|Bacilli	P	Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
HKD2_k127_4702655_6	1227360.C176_06307	2.465e-38	146.0	COG1930@1|root,COG1930@2|Bacteria,1VF03@1239|Firmicutes,4HNIU@91061|Bacilli,26FQX@186818|Planococcaceae	91061|Bacilli	P	Cobalt transport protein component CbiN	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
HKD2_k127_4702655_3	1403313.AXBR01000017_gene3854	6.976e-127	409.0	COG0310@1|root,COG0310@2|Bacteria,1TQVK@1239|Firmicutes,4HBKM@91061|Bacilli,1ZDXY@1386|Bacillus	91061|Bacilli	P	Cobalt uptake substrate-specific transmembrane region	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
HKD2_k127_4702655_5	1132442.KB889752_gene1939	4.814e-52	187.0	COG3411@1|root,COG3411@2|Bacteria,1UI4T@1239|Firmicutes,4HK77@91061|Bacilli,1ZGMB@1386|Bacillus	91061|Bacilli	C	Cobalamin biosynthesis protein	cbiW	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
HKD2_k127_4702655_0	1132442.KB889752_gene1938	2.689e-303	936.0	COG0155@1|root,COG1010@1|root,COG0155@2|Bacteria,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,4HCQ1@91061|Bacilli,1ZSCU@1386|Bacillus	91061|Bacilli	HP	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiH	-	2.1.1.272	ko:K21479	ko00860,ko01100,map00860,map01100	-	R11580	RC03479	ko00000,ko00001,ko01000	-	-	-	NIR_SIR,TP_methylase
HKD2_k127_4702655_1	1132442.KB889752_gene1937	1.175e-164	520.0	COG2138@1|root,COG2138@2|Bacteria,1TRDV@1239|Firmicutes,4H9RT@91061|Bacilli,1ZBYB@1386|Bacillus	91061|Bacilli	C	CbiX	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
HKD2_k127_4702655_7	1403313.AXBR01000017_gene3850	3.62e-18	84.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,4HC6V@91061|Bacilli,1ZDBU@1386|Bacillus	91061|Bacilli	H	Precorrin-6x reductase CbiJ/CobK	cbiJ	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
HKD2_k127_4761467_2	1423321.AS29_09850	3.218e-28	114.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_4761467_0	1131730.BAVI_11669	6.375e-205	642.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	atoB	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
HKD2_k127_4761467_1	1403313.AXBR01000012_gene1210	6.163e-29	117.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus	91061|Bacilli	KT	Transcriptional regulator	pspF	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
HKD2_k127_4762552_2	666686.B1NLA3E_13740	1.126e-92	308.0	290F4@1|root,2ZN4D@2|Bacteria,1V3B3@1239|Firmicutes,4HGA4@91061|Bacilli,1ZM30@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4762552_6	1174504.AJTN02000229_gene4412	2.366e-42	159.0	2CH4C@1|root,331QY@2|Bacteria,1VISK@1239|Firmicutes,4HNXZ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4762552_3	1273538.G159_00800	2.279e-90	302.0	COG1309@1|root,COG1309@2|Bacteria,1V85Y@1239|Firmicutes,4IPUB@91061|Bacilli,26I77@186818|Planococcaceae	91061|Bacilli	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HKD2_k127_4762552_0	1305836.AXVE01000011_gene588	1.701e-149	475.0	COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,26ERI@186818|Planococcaceae	91061|Bacilli	G	Cupin domain	yrkC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD2_k127_4762552_5	1117379.BABA_19931	9.395e-46	167.0	2CI5E@1|root,32S7D@2|Bacteria,1VA1W@1239|Firmicutes,4HKCJ@91061|Bacilli,1ZHWY@1386|Bacillus	91061|Bacilli	-	-	yxiS	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4762552_9	1196322.A370_01650	3.556e-28	114.0	2ED1S@1|root,336YP@2|Bacteria,1VJRI@1239|Firmicutes,24UCF@186801|Clostridia,36T2P@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4762552_4	1499968.TCA2_5134	5.122e-46	168.0	COG1309@1|root,COG1309@2|Bacteria,1V4HZ@1239|Firmicutes,4I2UT@91061|Bacilli,27435@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8
HKD2_k127_4762552_10	1499968.TCA2_5134	7.193e-18	83.0	COG1309@1|root,COG1309@2|Bacteria,1V4HZ@1239|Firmicutes,4I2UT@91061|Bacilli,27435@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8
HKD2_k127_4762552_8	1450694.BTS2_0259	2.845e-36	137.0	COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZEJ9@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	bacC	-	1.1.1.385	ko:K19548	ko01130,map01130	M00787	R10917	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD2_k127_4762552_1	1274374.CBLK010000059_gene362	2.334e-110	363.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,26SN4@186822|Paenibacillaceae	91061|Bacilli	P	3-mercaptopyruvate sulfurtransferase	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD2_k127_4762552_7	35841.BT1A1_1878	9.554e-37	142.0	COG0551@1|root,COG0551@2|Bacteria,1V93W@1239|Firmicutes,4HJZG@91061|Bacilli,1ZRAP@1386|Bacillus	91061|Bacilli	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,zf-C4_Topoisom
HKD2_k127_4768372_0	1403313.AXBR01000009_gene824	2.607e-127	411.0	COG5401@1|root,COG5401@2|Bacteria,1TPQD@1239|Firmicutes,4HB1S@91061|Bacilli,1ZBZJ@1386|Bacillus	91061|Bacilli	S	COG5401 Spore germination protein	gerM	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
HKD2_k127_4768372_1	1403313.AXBR01000009_gene820	4.282e-97	321.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1ZFJM@1386|Bacillus	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HKD2_k127_4768372_2	1403313.AXBR01000009_gene819	5.805e-73	249.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,1ZH0K@1386|Bacillus	91061|Bacilli	S	Phosphoesterase	ysnB	GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD2_k127_4768372_6	1196323.ALKF01000189_gene1185	1.711e-08	55.0	29R8B@1|root,30C9Q@2|Bacteria,1U9FB@1239|Firmicutes,4IJIN@91061|Bacilli,2713K@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4768372_3	1345697.M493_16125	6.058e-37	149.0	COG4932@1|root,COG4932@2|Bacteria,1UKU2@1239|Firmicutes,4IUK7@91061|Bacilli	91061|Bacilli	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4768372_4	1403313.AXBR01000009_gene807	1.368e-34	135.0	COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli,1ZHPP@1386|Bacillus	91061|Bacilli	S	GCN5-related N-acetyl-transferase	yjdJ	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
HKD2_k127_4768372_5	1403313.AXBR01000009_gene806	2.008e-22	99.0	COG1876@1|root,COG1876@2|Bacteria,1VC9C@1239|Firmicutes,4HNA4@91061|Bacilli,1ZGE1@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_4
HKD2_k127_4779198_0	1120973.AQXL01000088_gene3240	5.579e-69	245.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,279IT@186823|Alicyclobacillaceae	91061|Bacilli	NT	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
HKD2_k127_4779198_6	666686.B1NLA3E_19570	8.713e-08	57.0	2EM1V@1|root,33ERC@2|Bacteria,1VN9F@1239|Firmicutes,4HRI4@91061|Bacilli,1ZJBM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4779198_2	1196031.ALEG01000029_gene3691	1.593e-56	203.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD2_k127_4779198_8	768670.Calni_1745	0.0002758	45.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	nfuA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564	-	ko:K07400,ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn,NifU
HKD2_k127_4779198_5	1298598.JCM21714_4521	2.17e-09	58.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,471W7@74385|Gracilibacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_4779198_4	1243664.CAVL020000054_gene3105	1.436e-20	92.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZI0X@1386|Bacillus	91061|Bacilli	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_4779198_3	1243664.CAVL020000054_gene3106	8.779e-46	168.0	COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,4HKWP@91061|Bacilli,1ZH86@1386|Bacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_4779198_1	1340434.AXVA01000002_gene1179	7.806e-65	222.0	COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,4HBAW@91061|Bacilli,1ZAT5@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein R	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
HKD2_k127_4831220_2	1403313.AXBR01000027_gene5229	5.711e-78	264.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,4HH7C@91061|Bacilli,1ZFK0@1386|Bacillus	91061|Bacilli	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD2_k127_4831220_0	1403313.AXBR01000027_gene5230	9.132e-155	495.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus	91061|Bacilli	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HKD2_k127_4831220_3	1340434.AXVA01000010_gene5484	4.609e-09	59.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4831220_1	1403313.AXBR01000027_gene5231	1.124e-87	300.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,4HI5F@91061|Bacilli,1ZEE3@1386|Bacillus	91061|Bacilli	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
HKD2_k127_483514_3	1499680.CCFE01000021_gene2208	4.861e-116	376.0	COG1024@1|root,COG1024@2|Bacteria,1VRA3@1239|Firmicutes,4HV23@91061|Bacilli,1ZMH6@1386|Bacillus	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD2_k127_483514_2	1131730.BAVI_10637	1.012e-141	452.0	COG1028@1|root,COG1028@2|Bacteria,1TQZW@1239|Firmicutes,4HAS8@91061|Bacilli,1ZBWH@1386|Bacillus	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_483514_1	1499680.CCFE01000032_gene3887	1.889e-226	705.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,4HDWF@91061|Bacilli,1ZQT0@1386|Bacillus	91061|Bacilli	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_483514_0	1499680.CCFE01000021_gene2215	2.606e-245	762.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_4836150_3	1403313.AXBR01000007_gene108	9.133e-103	340.0	COG2265@1|root,COG2265@2|Bacteria,1V4AQ@1239|Firmicutes,4HHBA@91061|Bacilli,1ZCTE@1386|Bacillus	91061|Bacilli	J	Putative SAM-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
HKD2_k127_4836150_6	1403313.AXBR01000007_gene109	2.542e-68	238.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZGM0@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0403 family	yphP	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HKD2_k127_4836150_0	1403313.AXBR01000007_gene110	0.0	1075.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,1ZASK@1386|Bacillus	91061|Bacilli	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ILVD_EDD
HKD2_k127_4836150_1	1132442.KB889752_gene1354	1.319e-293	912.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,1ZBTF@1386|Bacillus	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD2_k127_4836150_4	1403313.AXBR01000007_gene116	4.733e-83	277.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,1ZGBN@1386|Bacillus	91061|Bacilli	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD2_k127_4836150_7	1403313.AXBR01000007_gene117	1.723e-53	194.0	2CFTY@1|root,336V6@2|Bacteria,1VH1W@1239|Firmicutes,4HQI3@91061|Bacilli,1ZH6G@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4836150_2	1403313.AXBR01000007_gene118	6.235e-162	514.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,1ZCTU@1386|Bacillus	91061|Bacilli	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
HKD2_k127_4836150_5	1403313.AXBR01000007_gene121	2.875e-80	268.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,1ZFKR@1386|Bacillus	91061|Bacilli	K	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon	mntR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD2_k127_4836150_8	1444310.JANV01000017_gene2870	5.335e-52	185.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
HKD2_k127_483800_4	44251.PDUR_23735	1.026e-08	57.0	2DMHQ@1|root,32RMG@2|Bacteria,1VB95@1239|Firmicutes,4HKKS@91061|Bacilli,26XJZ@186822|Paenibacillaceae	91061|Bacilli	S	Arsenic resistance operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
HKD2_k127_483800_0	1384049.CD29_18955	4.358e-230	727.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,4HBKG@91061|Bacilli,3IW3N@400634|Lysinibacillus	91061|Bacilli	D	transporter ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
HKD2_k127_483800_3	1211035.CD30_15190	3.539e-27	113.0	2EB88@1|root,3358Q@2|Bacteria,1VFAE@1239|Firmicutes,4HQCI@91061|Bacilli,3IYKT@400634|Lysinibacillus	91061|Bacilli	S	Fe-S cluster assembly protein HesB	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_483800_2	1403313.AXBR01000022_gene2796	1.31e-61	218.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,4HP7F@91061|Bacilli,1ZH5E@1386|Bacillus	91061|Bacilli	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD2_k127_483800_1	1243664.CAVL020000008_gene4058	3.721e-110	359.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	yxeK	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_4850669_15	1243664.CAVL020000010_gene4540	1.496e-92	306.0	COG1960@1|root,COG1960@2|Bacteria,1VQUR@1239|Firmicutes,4HU1X@91061|Bacilli,1ZE36@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	ko:K04117	ko00362,ko01120,map00362,map01120	M00540	R05619	RC02035	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_4850669_24	1340434.AXVA01000010_gene5484	9.76e-08	57.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4850669_21	1123290.AUDQ01000009_gene1338	1.088e-46	179.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_4850669_6	1123290.AUDQ01000009_gene1325	1.831e-171	543.0	COG2159@1|root,COG2159@2|Bacteria,1UZAH@1239|Firmicutes,4HA5S@91061|Bacilli	91061|Bacilli	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
HKD2_k127_4850669_14	666686.B1NLA3E_13985	3.02e-93	315.0	COG0346@1|root,COG0346@2|Bacteria,1U9II@1239|Firmicutes,4IJP6@91061|Bacilli,1ZANJ@1386|Bacillus	91061|Bacilli	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	1.13.11.14	ko:K10621	ko00362,ko00622,ko01120,ko01220,map00362,map00622,map01120,map01220	M00539	R01507,R05248	RC00387,RC01308	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HKD2_k127_4850669_17	666686.B1NLA3E_13990	1.435e-76	259.0	COG5517@1|root,COG5517@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	-	-	1.14.12.25	ko:K16303	ko00622,ko01120,ko01220,map00622,map01120,map01220	M00539	R05247	RC00267	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Ring_hydroxyl_B
HKD2_k127_4850669_4	666686.B1NLA3E_13995	8.391e-201	632.0	COG4638@1|root,COG4638@2|Bacteria,1TSW4@1239|Firmicutes,4HDEH@91061|Bacilli,1ZBPN@1386|Bacillus	91061|Bacilli	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.12.25	ko:K10619	ko00622,ko01120,ko01220,map00622,map01120,map01220	M00539	R05247	RC00267	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
HKD2_k127_4850669_10	666686.B1NLA3E_14005	4.743e-130	418.0	COG1028@1|root,COG1028@2|Bacteria,1TR8Y@1239|Firmicutes,4HFAC@91061|Bacilli,1ZFFW@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.3.1.58	ko:K10620	ko00622,ko01120,ko01220,map00622,map01120,map01220	M00539	R05240	RC00057	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD2_k127_4850669_5	1243664.CAVL020000010_gene4539	1.564e-175	559.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus	91061|Bacilli	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
HKD2_k127_4850669_19	1117379.BABA_12675	6.057e-53	190.0	COG2030@1|root,COG2030@2|Bacteria,1U5N7@1239|Firmicutes,4IFCY@91061|Bacilli,1ZHEK@1386|Bacillus	91061|Bacilli	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HKD2_k127_4850669_20	1403313.AXBR01000022_gene2830	6.888e-48	173.0	2CKNI@1|root,32SCP@2|Bacteria,1VCRC@1239|Firmicutes,4HKG2@91061|Bacilli,1ZIAD@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF3870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3870
HKD2_k127_4850669_3	1403313.AXBR01000022_gene2832	1.569e-204	642.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,1ZB0F@1386|Bacillus	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HKD2_k127_4850669_23	1131730.BAVI_11359	4.202e-09	59.0	2EMM7@1|root,33F9K@2|Bacteria,1VN2S@1239|Firmicutes,4HPA1@91061|Bacilli,1ZK7D@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4850669_13	1174504.AJTN02000229_gene4364	9.099e-97	332.0	2DBJR@1|root,2Z9N7@2|Bacteria,1TQ49@1239|Firmicutes,4HB42@91061|Bacilli,1ZQMP@1386|Bacillus	91061|Bacilli	S	Spore germination B3/ GerAC like, C-terminal	-	-	-	ko:K06297	-	-	-	-	ko00000	-	-	-	Spore_GerAC
HKD2_k127_4850669_12	1174504.AJTN02000229_gene4365	2.996e-103	348.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZE5W@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD2_k127_4850669_2	1122915.AUGY01000020_gene6464	5.506e-205	649.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,26QBX@186822|Paenibacillaceae	91061|Bacilli	EG	Spore germination protein	-	-	-	ko:K06295,ko:K06307	-	-	-	-	ko00000	-	-	-	GerA
HKD2_k127_4850669_8	1403313.AXBR01000001_gene3931	1.893e-156	501.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZDQT@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD2_k127_4850669_18	1403313.AXBR01000001_gene3931	8.399e-62	218.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZDQT@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD2_k127_4850669_7	1403313.AXBR01000001_gene3931	3.479e-159	509.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZDQT@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD2_k127_4850669_22	1449063.JMLS01000001_gene4287	1.425e-18	88.0	2EMM7@1|root,33F9K@2|Bacteria,1VN2S@1239|Firmicutes,4HPA1@91061|Bacilli,26ZU1@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4850669_9	1403313.AXBR01000001_gene3933	6.958e-147	475.0	2DBJR@1|root,2Z9N7@2|Bacteria,1TQ49@1239|Firmicutes,4HB42@91061|Bacilli,1ZQMP@1386|Bacillus	91061|Bacilli	S	Spore germination B3/ GerAC like, C-terminal	-	-	-	ko:K06297	-	-	-	-	ko00000	-	-	-	Spore_GerAC
HKD2_k127_4850669_0	1403313.AXBR01000001_gene3934	2.039e-257	802.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus	91061|Bacilli	EG	Spore germination protein	-	-	-	ko:K06295,ko:K06307	-	-	-	-	ko00000	-	-	-	GerA
HKD2_k127_4850669_11	1117379.BABA_02632	5.746e-119	386.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,1ZDFC@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
HKD2_k127_4850669_1	1117379.BABA_02627	1.012e-239	747.0	COG1304@1|root,COG1304@2|Bacteria,1UIFC@1239|Firmicutes,4HANY@91061|Bacilli,1ZD7G@1386|Bacillus	91061|Bacilli	C	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
HKD2_k127_4850669_16	665959.HMPREF1013_04066	4.96e-79	269.0	COG1304@1|root,COG1304@2|Bacteria,1UIFC@1239|Firmicutes,4HANY@91061|Bacilli,1ZD7G@1386|Bacillus	91061|Bacilli	C	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
HKD2_k127_48569_5	1403313.AXBR01000009_gene789	5.728e-19	86.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,1ZCR0@1386|Bacillus	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
HKD2_k127_48569_1	1403313.AXBR01000009_gene790	6.153e-139	445.0	COG0755@1|root,COG0755@2|Bacteria,1U8IP@1239|Firmicutes,4HD6H@91061|Bacilli,1ZBFP@1386|Bacillus	91061|Bacilli	O	cytochrome C	hemX	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	ko:K02497	-	-	-	-	ko00000	-	-	-	Cytochrom_C_asm
HKD2_k127_48569_0	1403313.AXBR01000009_gene791	5.48e-237	738.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08420	GlutR_N,GlutR_dimer,Shikimate_DH
HKD2_k127_48569_4	1403313.AXBR01000009_gene792	8.918e-60	210.0	2CYGZ@1|root,32T47@2|Bacteria,1VA1R@1239|Firmicutes,4HM46@91061|Bacilli,1ZGJG@1386|Bacillus	91061|Bacilli	-	-	ysxD	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_48569_2	1403313.AXBR01000009_gene793	2.202e-107	350.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,1ZBX7@1386|Bacillus	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD2_k127_48569_3	326423.RBAM_025260	1.129e-66	229.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus	91061|Bacilli	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD2_k127_4865692_6	1211814.CAPG01000020_gene737	6.707e-66	229.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,1ZCIY@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
HKD2_k127_4865692_1	1243664.CAVL020000049_gene5146	6.848e-118	383.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HDSC@91061|Bacilli,1ZAW3@1386|Bacillus	91061|Bacilli	P	binding-protein-dependent transport systems inner membrane component	ssuC	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
HKD2_k127_4865692_2	1034347.CAHJ01000073_gene2829	2.184e-98	327.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,4HAFM@91061|Bacilli,1ZDWC@1386|Bacillus	91061|Bacilli	P	ABC transporter, ATP-binding protein	-	-	-	ko:K02049,ko:K15600	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	ABC_tran
HKD2_k127_4865692_0	981383.AEWH01000042_gene1683	2.503e-126	406.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HD73@91061|Bacilli	91061|Bacilli	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
HKD2_k127_4865692_3	1121289.JHVL01000009_gene1428	3.462e-75	263.0	COG1226@1|root,COG1226@2|Bacteria,1V2CY@1239|Firmicutes,24DT6@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
HKD2_k127_4865692_4	1132442.KB889752_gene1839	4.511e-69	235.0	COG2940@1|root,COG2940@2|Bacteria,1V4EX@1239|Firmicutes,4HH4C@91061|Bacilli,1ZGBM@1386|Bacillus	91061|Bacilli	S	COG2940 Proteins containing SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD2_k127_4865692_5	649747.HMPREF0083_05526	5.317e-66	228.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,26RVP@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD2_k127_4896636_2	1334046.AYTB01000009_gene2119	1.165e-27	124.0	COG4314@1|root,COG4314@2|Bacteria,1V8NY@1239|Firmicutes,4HIVN@91061|Bacilli	2|Bacteria	C	NosL	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD2_k127_4896636_1	1145276.T479_09015	5.818e-60	218.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD2_k127_4896636_0	1340434.AXVA01000004_gene2639	1.029e-213	665.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBDW@91061|Bacilli,1ZM7Q@1386|Bacillus	91061|Bacilli	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD2_k127_494638_1	1034347.CAHJ01000084_gene1339	1.144e-81	272.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1ZQ3H@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	bglA	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HKD2_k127_494638_2	1034347.CAHJ01000084_gene1340	2.856e-45	166.0	COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,1ZI2Z@1386|Bacillus	91061|Bacilli	G	phosphotransferase system	licA	-	2.7.1.196,2.7.1.205,2.7.1.207	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	M00275,M00281	R04393,R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.1,4.A.3.2	-	iYO844.BSU38570	PTS_IIA
HKD2_k127_494638_0	1034347.CAHJ01000084_gene1341	5.598e-220	688.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,1ZBJ7@1386|Bacillus	91061|Bacilli	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	licC	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	iYO844.BSU38390	PTS_EIIC
HKD2_k127_494638_3	1034347.CAHJ01000084_gene1342	8.453e-40	148.0	COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HM5Q@91061|Bacilli,1ZIC3@1386|Bacillus	91061|Bacilli	G	transporter subunit IIB	licB	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
HKD2_k127_4953669_13	1340434.AXVA01000016_gene701	3.602e-05	48.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4953669_11	935837.JAEK01000020_gene600	4.347e-10	63.0	2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes,4HR4K@91061|Bacilli,1ZJ6X@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD2_k127_4953669_9	1403313.AXBR01000012_gene1233	3.498e-21	94.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,4HRAS@91061|Bacilli,1ZIVB@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD2_k127_4953669_7	935836.JAEL01000007_gene2896	1.277e-45	168.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,1ZQA5@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HKD2_k127_4953669_4	1403313.AXBR01000022_gene2757	6.404e-138	443.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,1ZCNQ@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	potA5	-	-	ko:K01990,ko:K16921	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_4953669_3	1403313.AXBR01000022_gene2756	3.315e-150	497.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus	91061|Bacilli	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
HKD2_k127_4953669_8	1243664.CAVL020000025_gene1694	2.56e-34	131.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHTU@1386|Bacillus	91061|Bacilli	K	Cold-shock protein	cspE	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_4953669_0	1078085.HMPREF1210_01379	5.515e-257	800.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,26E9Q@186818|Planococcaceae	91061|Bacilli	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HKD2_k127_4953669_6	1174504.AJTN02000180_gene1979	1.564e-101	343.0	COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAK1@91061|Bacilli,1ZPXF@1386|Bacillus	91061|Bacilli	T	Putative diguanylate phosphodiesterase	M1-600	-	-	-	-	-	-	-	-	-	-	-	EAL
HKD2_k127_4953669_2	1403313.AXBR01000022_gene2748	1.652e-164	526.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBDZ@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD2_k127_4953669_1	1174504.AJTN02000180_gene1974	5.636e-242	756.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
HKD2_k127_4953669_5	1403313.AXBR01000022_gene2745	5.151e-122	395.0	COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,1ZBPQ@1386|Bacillus	91061|Bacilli	P	COG0861 Membrane protein TerC, possibly involved in tellurium resistance	ykoY	-	-	-	-	-	-	-	-	-	-	-	TerC
HKD2_k127_4953669_12	666686.B1NLA3E_10425	2.966e-08	57.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	666686.B1NLA3E_10425|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_4987172_5	1403313.AXBR01000027_gene5243	9.231e-58	205.0	COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF2529)	ywjG	-	-	-	-	-	-	-	-	-	-	-	DUF2529
HKD2_k127_4987172_4	1403313.AXBR01000027_gene5242	3.422e-66	227.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,4HICG@91061|Bacilli,1ZQRZ@1386|Bacillus	91061|Bacilli	T	COG0784 FOG CheY-like receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
HKD2_k127_4987172_1	1403313.AXBR01000027_gene5241	1.351e-158	503.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,1ZBBA@1386|Bacillus	91061|Bacilli	G	Aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HKD2_k127_4987172_3	1174504.AJTN02000194_gene4182	2.759e-115	373.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,1ZCA6@1386|Bacillus	91061|Bacilli	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU37110	TAL_FSA
HKD2_k127_4987172_0	1403313.AXBR01000027_gene5239	5.633e-247	766.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZASB@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU37100	EPSP_synthase
HKD2_k127_4987172_2	1403313.AXBR01000027_gene5238	3.54e-130	417.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZC28@1386|Bacillus	91061|Bacilli	G	fructose-1,6-bisphosphatase	glpX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
HKD2_k127_5033163_0	1403313.AXBR01000009_gene834	0.0	1079.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,1ZBY1@1386|Bacillus	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD2_k127_5033163_4	1403313.AXBR01000009_gene835	6.103e-52	184.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,1ZGXM@1386|Bacillus	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD2_k127_5033163_3	1196031.ALEG01000039_gene1398	1.825e-140	452.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,1ZAZT@1386|Bacillus	91061|Bacilli	EJ	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D	ansB	GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD2_k127_5033163_1	1174504.AJTN02000191_gene4255	1.568e-181	571.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus	91061|Bacilli	C	Electron transfer flavoprotein	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HKD2_k127_5033163_2	1403313.AXBR01000009_gene837	9.985e-146	464.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4H9QY@91061|Bacilli,1ZBTA@1386|Bacillus	91061|Bacilli	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD2_k127_5033163_5	1382358.JHVN01000011_gene2005	4.668e-36	138.0	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,21VAE@150247|Anoxybacillus	91061|Bacilli	K	YsiA-like protein, C-terminal region	fadR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
HKD2_k127_5038349_2	1403313.AXBR01000022_gene2764	2.573e-101	334.0	COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,1ZE6C@1386|Bacillus	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HKD2_k127_5038349_3	1408303.JNJJ01000073_gene3419	1.172e-64	223.0	COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus	91061|Bacilli	S	general stress protein	ydaG	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyrid_ox_like
HKD2_k127_5038349_1	1403313.AXBR01000022_gene2768	1.855e-189	595.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,4HBDK@91061|Bacilli,1ZBP8@1386|Bacillus	91061|Bacilli	G	peptidase M42	yhfE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD2_k127_5038349_0	1174504.AJTN02000013_gene3842	1.155e-213	672.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,1ZC4E@1386|Bacillus	91061|Bacilli	E	COG0747 ABC-type dipeptide transport system, periplasmic component	oppA1	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD2_k127_5038836_7	871968.DESME_03435	1.315e-13	70.0	2EG90@1|root,33A0T@2|Bacteria,1VMNR@1239|Firmicutes,2552Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5038836_0	1117379.BABA_05451	0.0	1165.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,1UJG9@1239|Firmicutes,4IT8Z@91061|Bacilli,1ZSAH@1386|Bacillus	91061|Bacilli	T	Four helix bundle sensory module for signal transduction	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
HKD2_k127_5038836_2	1340434.AXVA01000003_gene2418	5.988e-125	406.0	COG1352@1|root,COG1352@2|Bacteria,1TRTF@1239|Firmicutes,4HDN6@91061|Bacilli,1ZBAF@1386|Bacillus	91061|Bacilli	NT	chemotaxis	cheR5	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
HKD2_k127_5038836_1	1340434.AXVA01000003_gene2419	1.413e-287	897.0	COG3437@1|root,COG3852@1|root,COG3437@2|Bacteria,COG3852@2|Bacteria,1V2ZS@1239|Firmicutes,4HG6V@91061|Bacilli,1ZDT9@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_8,PAS_9,Response_reg,dCache_1
HKD2_k127_5038836_3	1117379.BABA_05466	3.385e-119	390.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,1ZFR9@1386|Bacillus	91061|Bacilli	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
HKD2_k127_5038836_5	1211814.CAPG01000090_gene4114	2.803e-86	296.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4HEI3@91061|Bacilli,1ZD2G@1386|Bacillus	91061|Bacilli	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	pucA	-	1.17.1.4	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	XdhC_C,XdhC_CoxI
HKD2_k127_5038836_6	1211814.CAPG01000090_gene4113	2.125e-36	145.0	COG2068@1|root,COG2068@2|Bacteria,1VA0B@1239|Firmicutes,4HMD3@91061|Bacilli,1ZI29@1386|Bacillus	91061|Bacilli	S	MobA-like NTP transferase domain	pucB	-	1.17.1.4,2.7.7.76	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	M00546	R01768,R02103,R11582	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3
HKD2_k127_5038836_4	1174504.AJTN02000220_gene1340	4.176e-101	335.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,1ZC08@1386|Bacillus	91061|Bacilli	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HKD2_k127_504182_0	1196322.A370_00614	8.719e-126	407.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia,36EXG@31979|Clostridiaceae	186801|Clostridia	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD2_k127_504182_5	1403313.AXBR01000023_gene2506	8.919e-10	62.0	29SHD@1|root,30DNF@2|Bacteria,1UBG7@1239|Firmicutes,4IMUX@91061|Bacilli,1ZKW6@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_504182_3	665952.HMPREF1015_02656	1.391e-57	204.0	COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,1ZGHR@1386|Bacillus	91061|Bacilli	S	DoxX	ydfP	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD2_k127_504182_2	326423.RBAM_002440	2.154e-78	268.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus	91061|Bacilli	M	effector of murein hydrolase	yxaC	-	-	-	-	-	-	-	-	-	-	-	LrgB
HKD2_k127_504182_4	1033738.CAEP01000005_gene2371	1.412e-26	113.0	COG1380@1|root,COG1380@2|Bacteria,1VE19@1239|Firmicutes,4HMWP@91061|Bacilli,26G51@186818|Planococcaceae	91061|Bacilli	S	LrgA family	-	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
HKD2_k127_504182_1	1536774.H70357_34565	1.301e-78	270.0	COG2220@1|root,COG2220@2|Bacteria,1TSSV@1239|Firmicutes,4HCSS@91061|Bacilli,26U52@186822|Paenibacillaceae	91061|Bacilli	S	Zn-dependent hydrolases of the beta-lactamase fold	yddR	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
HKD2_k127_504182_6	1340434.AXVA01000010_gene5484	2.081e-09	59.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5049558_3	1403313.AXBR01000007_gene403	2.144e-88	295.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus	91061|Bacilli	CO	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD2_k127_5049558_0	1403313.AXBR01000007_gene402	1.511e-255	797.0	COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus	91061|Bacilli	O	COG1333 ResB protein required for cytochrome c biosynthesis	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
HKD2_k127_5049558_1	935836.JAEL01000085_gene4648	1.185e-183	580.0	COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli,1ZBH9@1386|Bacillus	91061|Bacilli	O	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'	resC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
HKD2_k127_5049558_2	1403313.AXBR01000007_gene400	3.213e-108	351.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZC0F@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_505206_1	1132442.KB889752_gene3696	8.483e-80	268.0	COG2318@1|root,COG2318@2|Bacteria,1VG45@1239|Firmicutes,4HPNV@91061|Bacilli,1ZH17@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD2_k127_505206_0	1243664.CAVL020000037_gene1071	1.881e-171	541.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus	91061|Bacilli	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
HKD2_k127_505206_2	1243664.CAVL020000037_gene1072	1.03e-28	116.0	COG1414@1|root,COG1414@2|Bacteria,1V7RC@1239|Firmicutes,4HITR@91061|Bacilli,1ZER9@1386|Bacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_5070127_4	665959.HMPREF1013_01214	4.347e-10	63.0	29T57@1|root,30EBY@2|Bacteria,1UCD9@1239|Firmicutes,4INVP@91061|Bacilli,1ZP0I@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5070127_3	1231057.AMGD01000112_gene342	4.632e-14	76.0	COG4584@1|root,COG4584@2|Bacteria,1VE5Y@1239|Firmicutes,4HR01@91061|Bacilli,26HIN@186818|Planococcaceae	91061|Bacilli	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
HKD2_k127_5070127_5	1123511.KB905841_gene1347	5.624e-09	61.0	2F74G@1|root,33ZK1@2|Bacteria,1VXEF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5070127_1	1121895.Q765_14730	6.363e-15	81.0	2EA8P@1|root,334D5@2|Bacteria,4PFV3@976|Bacteroidetes,1IDCS@117743|Flavobacteriia,2NY0V@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5070127_2	1285586.H131_10588	2.867e-14	76.0	2EMBB@1|root,32EHI@2|Bacteria,1TZHT@1239|Firmicutes,4HRI0@91061|Bacilli,3IZSU@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5070127_0	1347369.CCAD010000078_gene3007	1.771e-70	243.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HN1F@91061|Bacilli,1ZGFZ@1386|Bacillus	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_5105127_14	1169144.KB910926_gene1136	8.131e-37	144.0	COG1807@1|root,COG1807@2|Bacteria,1V114@1239|Firmicutes,4HB64@91061|Bacilli,1ZDJ4@1386|Bacillus	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD2_k127_5105127_0	666686.B1NLA3E_03090	0.0	2217.0	COG2132@1|root,COG4733@1|root,COG2132@2|Bacteria,COG4733@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,1ZD48@1386|Bacillus	91061|Bacilli	Q	multicopper oxidases	cotA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD2_k127_5105127_11	935837.JAEK01000020_gene641	4.026e-64	242.0	COG0627@1|root,COG0627@2|Bacteria,1V28D@1239|Firmicutes,4HNGJ@91061|Bacilli,1ZEGT@1386|Bacillus	91061|Bacilli	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N,Y_Y_Y
HKD2_k127_5105127_13	1211817.CCAT010000062_gene3907	1.339e-43	175.0	COG2247@1|root,COG3227@1|root,COG4886@1|root,COG2247@2|Bacteria,COG3227@2|Bacteria,COG4886@2|Bacteria,1VS6B@1239|Firmicutes	1239|Firmicutes	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,DUF5011
HKD2_k127_5105127_12	406124.ACPC01000019_gene2786	1.389e-53	201.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,4IJZY@91061|Bacilli,1ZEW6@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	-	-	-	ko:K19220,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM
HKD2_k127_5105127_8	666686.B1NLA3E_04280	5.33e-98	327.0	COG1305@1|root,COG1305@2|Bacteria,1V4HE@1239|Firmicutes,4HD3Q@91061|Bacilli,1ZGN3@1386|Bacillus	91061|Bacilli	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,Bact_transglu_N,Transglut_core
HKD2_k127_5105127_9	717606.PaecuDRAFT_2500	6.668e-81	280.0	COG2307@1|root,COG2307@2|Bacteria,1V4RG@1239|Firmicutes,4HHBV@91061|Bacilli,272HQ@186822|Paenibacillaceae	91061|Bacilli	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HKD2_k127_5105127_1	324057.Pjdr2_6152	2.715e-211	666.0	COG2308@1|root,COG2308@2|Bacteria,1TPA5@1239|Firmicutes,4HE51@91061|Bacilli,26UNZ@186822|Paenibacillaceae	91061|Bacilli	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
HKD2_k127_5105127_2	1403313.AXBR01000028_gene5064	3.574e-198	620.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli,1ZBCJ@1386|Bacillus	91061|Bacilli	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD2_k127_5105127_5	1078085.HMPREF1210_01628	3.715e-122	407.0	2C55H@1|root,2ZAGR@2|Bacteria,1V118@1239|Firmicutes,4HFBF@91061|Bacilli	91061|Bacilli	-	-	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Cu_amine_oxidN1,PD40
HKD2_k127_5105127_6	796606.BMMGA3_03665	1.491e-120	393.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus	91061|Bacilli	P	Phosphate	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD2_k127_5105127_4	1078085.HMPREF1210_01630	1.555e-126	411.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,26HCN@186818|Planococcaceae	91061|Bacilli	U	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD2_k127_5105127_7	1078085.HMPREF1210_01631	6.517e-119	388.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,26FHS@186818|Planococcaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD2_k127_5105127_3	1033734.CAET01000054_gene1433	4.383e-173	548.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus	91061|Bacilli	S	COG2270 Permeases of the major facilitator superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD2_k127_5105498_2	1444309.JAQG01000090_gene1244	7.519e-19	100.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,4HIQ8@91061|Bacilli,26V5R@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	RNDmfp	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD2_k127_5105498_1	666686.B1NLA3E_04365	5.434e-158	501.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD2_k127_5105498_0	1169144.KB910980_gene1534	3.32e-283	881.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli,1ZB9K@1386|Bacillus	91061|Bacilli	GM	Polysaccharide biosynthesis protein	pglF	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	-	ko:K19421	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Polysacc_synt_2
HKD2_k127_5127811_6	315730.BcerKBAB4_1370	1.374e-29	120.0	COG1994@1|root,COG1994@2|Bacteria,1TSA9@1239|Firmicutes,4HEQY@91061|Bacilli,1ZFIC@1386|Bacillus	91061|Bacilli	S	Zn-dependent	M1-843	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HKD2_k127_5127811_7	1403313.AXBR01000007_gene215	4.514e-09	57.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli,1ZC3V@1386|Bacillus	91061|Bacilli	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
HKD2_k127_5127811_4	1033810.HLPCO_001480	2.048e-61	219.0	COG1136@1|root,COG1136@2|Bacteria,2NQWU@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_5127811_5	880447.MSB_A0027	1.282e-56	205.0	COG1136@1|root,COG1136@2|Bacteria,3WSX2@544448|Tenericutes	544448|Tenericutes	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_5127811_3	1033810.HLPCO_001479	1.58e-61	239.0	COG0577@1|root,COG0577@2|Bacteria,2NR29@2323|unclassified Bacteria	2|Bacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD2_k127_5127811_2	1131730.BAVI_25160	4.168e-93	310.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,1ZD1X@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ykoG3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_5127811_1	545693.BMQ_5023	1.204e-144	472.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus	91061|Bacilli	T	Histidine kinase	ykoH3	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_5127811_8	1403313.AXBR01000006_gene80	2.36e-07	52.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,4HE2P@91061|Bacilli,1ZBET@1386|Bacillus	91061|Bacilli	E	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
HKD2_k127_5127811_0	1340434.AXVA01000011_gene3207	0.0	1296.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZS1A@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
HKD2_k127_5170871_7	1403313.AXBR01000010_gene975	8.104e-119	384.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,1ZAP2@1386|Bacillus	91061|Bacilli	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HKD2_k127_5170871_14	1403313.AXBR01000010_gene976	6.938e-35	136.0	2E43M@1|root,32YZY@2|Bacteria,1VAYB@1239|Firmicutes,4HNNI@91061|Bacilli,1ZHTZ@1386|Bacillus	91061|Bacilli	S	YtzH-like protein	ytzH	-	-	-	-	-	-	-	-	-	-	-	YtzH
HKD2_k127_5170871_5	1403313.AXBR01000010_gene977	3.914e-134	430.0	COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus	91061|Bacilli	M	Phosphotransferase	ytmP	-	-	-	-	-	-	-	-	-	-	-	APH
HKD2_k127_5170871_3	1403313.AXBR01000010_gene979	7.132e-141	453.0	28NSI@1|root,2ZB4U@2|Bacteria,1UZ00@1239|Firmicutes,4HDBT@91061|Bacilli,1ZDNP@1386|Bacillus	91061|Bacilli	-	-	ytlQ	-	-	-	-	-	-	-	-	-	-	-	NERD
HKD2_k127_5170871_11	1174504.AJTN02000004_gene2491	1.127e-57	206.0	COG1514@1|root,COG1514@2|Bacteria,1VCBK@1239|Firmicutes,4HM3V@91061|Bacilli,1ZHT8@1386|Bacillus	91061|Bacilli	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ytlP	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
HKD2_k127_5170871_15	1405.DJ92_3417	1.641e-25	108.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HCSH@91061|Bacilli,1ZCZY@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_5170871_2	1174504.AJTN02000004_gene2489	4.239e-229	716.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus	91061|Bacilli	E	Dipeptidase	ytjP	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
HKD2_k127_5170871_16	1340434.AXVA01000010_gene5484	7.678e-11	66.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5170871_10	1403313.AXBR01000010_gene986	3.138e-69	237.0	COG0586@1|root,COG0586@2|Bacteria,1V8A4@1239|Firmicutes,4HHUU@91061|Bacilli,1ZH0M@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	ybfM3	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD2_k127_5170871_9	1403313.AXBR01000010_gene987	3.758e-93	308.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZRQR@1386|Bacillus	91061|Bacilli	U	Belongs to the peptidase S26 family	sipS	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD2_k127_5170871_8	1403313.AXBR01000010_gene995	6.185e-104	342.0	COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,1ZD4M@1386|Bacillus	91061|Bacilli	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	frnE	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	DSBA
HKD2_k127_5170871_12	1403313.AXBR01000010_gene996	1.098e-55	199.0	COG1959@1|root,COG1959@2|Bacteria,1VEBJ@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD2_k127_5170871_13	1174504.AJTN02000004_gene2477	1.301e-37	141.0	COG1349@1|root,COG1349@2|Bacteria,1VG5N@1239|Firmicutes,4HNPQ@91061|Bacilli,1ZHT3@1386|Bacillus	91061|Bacilli	K	COG1349 Transcriptional regulators of sugar metabolism	ytzE	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
HKD2_k127_5170871_6	1403313.AXBR01000010_gene1015	6.205e-124	400.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,1ZCAM@1386|Bacillus	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD2_k127_5170871_17	1340434.AXVA01000010_gene5484	7.717e-08	57.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5170871_1	1403313.AXBR01000010_gene1016	5.413e-232	728.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	ytgP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
HKD2_k127_5170871_0	1403313.AXBR01000010_gene1017	2.264e-246	764.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus	91061|Bacilli	S	HI0933-like protein	ytfP	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD2_k127_5170871_4	634956.Geoth_1943	1.252e-138	450.0	COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	hemAT	-	-	ko:K06595	-	-	-	-	ko00000,ko02035	-	-	-	MCPsignal,Protoglobin
HKD2_k127_5175277_7	202954.BBNK01000048_gene890	9.367e-42	154.0	2AEWM@1|root,31RBG@2|Bacteria,1QNVG@1224|Proteobacteria,1TMHR@1236|Gammaproteobacteria,3NNG2@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5175277_1	1029823.AFIE01000002_gene2390	7.624e-138	442.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,3NKEG@468|Moraxellaceae	1236|Gammaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
HKD2_k127_5175277_6	1029823.AFIE01000078_gene360	2.631e-47	169.0	2BIP3@1|root,32CWA@2|Bacteria,1NDYW@1224|Proteobacteria,1SG65@1236|Gammaproteobacteria,3NP5S@468|Moraxellaceae	1236|Gammaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
HKD2_k127_5175277_3	202952.BBLI01000074_gene3554	7.204e-65	223.0	COG4226@1|root,COG4226@2|Bacteria,1PWGA@1224|Proteobacteria,1S6AD@1236|Gammaproteobacteria,3NNQ6@468|Moraxellaceae	1236|Gammaproteobacteria	S	HicB family	hicB	-	-	-	-	-	-	-	-	-	-	-	HicB
HKD2_k127_5175277_0	106648.BBLJ01000071_gene4291	2.128e-244	764.0	COG0488@1|root,COG0488@2|Bacteria,1MV25@1224|Proteobacteria,1RNM9@1236|Gammaproteobacteria,3NKQC@468|Moraxellaceae	1236|Gammaproteobacteria	S	ABC transporter	ydiF	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD2_k127_5175277_4	202956.BBNL01000051_gene1016	9.966e-61	210.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,1SCNC@1236|Gammaproteobacteria,3NNZB@468|Moraxellaceae	1236|Gammaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
HKD2_k127_5175277_5	40215.BBOS01000100_gene638	2.488e-53	189.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,1SC8G@1236|Gammaproteobacteria,3NP1M@468|Moraxellaceae	1236|Gammaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD2_k127_5185276_2	1211814.CAPG01000056_gene2781	8.674e-60	207.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,1ZAZB@1386|Bacillus	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HKD2_k127_5185276_0	1403313.AXBR01000013_gene1341	2.447e-295	910.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli,1ZAPE@1386|Bacillus	91061|Bacilli	G	Catalyzes the interconversion of 2-phosphoglycerate and	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HKD2_k127_5185276_1	315749.Bcer98_3680	8.269e-113	368.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,1ZB6N@1386|Bacillus	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HKD2_k127_5185276_3	1294265.JCM21738_4341	7.484e-42	154.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1ZCXW@1386|Bacillus	91061|Bacilli	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
HKD2_k127_520342_0	383372.Rcas_3244	5.545e-180	595.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
HKD2_k127_520342_1	1321778.HMPREF1982_01030	8.185e-33	129.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,269FS@186813|unclassified Clostridiales	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HKD2_k127_5204907_2	1132442.KB889752_gene1051	2.094e-88	293.0	COG4807@1|root,COG4807@2|Bacteria,1V4DA@1239|Firmicutes,4HH2A@91061|Bacilli,1ZFS1@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1456)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
HKD2_k127_5204907_0	666686.B1NLA3E_07405	9.648e-264	817.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,1ZB39@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes	dbpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD2_k127_5204907_3	946235.CAER01000062_gene3487	1.628e-20	92.0	2ES1B@1|root,33JKC@2|Bacteria,1VQEH@1239|Firmicutes,4HSU8@91061|Bacilli,23M9K@182709|Oceanobacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2187
HKD2_k127_5204907_1	1403313.AXBR01000012_gene1210	6.919e-200	634.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus	91061|Bacilli	KT	Transcriptional regulator	pspF	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
HKD2_k127_522011_3	1403313.AXBR01000009_gene892	2.748e-76	259.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,1ZBGS@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_522011_1	1340434.AXVA01000005_gene4545	4.643e-170	538.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZC27@1386|Bacillus	91061|Bacilli	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HKD2_k127_522011_0	1211814.CAPG01000051_gene2679	4.734e-254	786.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus	91061|Bacilli	C	isocitrate	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD2_k127_522011_2	1403313.AXBR01000009_gene895	2.129e-152	483.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1ZBAY@1386|Bacillus	91061|Bacilli	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD2_k127_5228758_0	304371.MCP_2903	1.151e-12	68.0	COG0431@1|root,arCOG04624@2157|Archaea,2Y71Q@28890|Euryarchaeota,2NB37@224756|Methanomicrobia	224756|Methanomicrobia	S	Flavodoxin-like fold	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
HKD2_k127_5228758_1	1502851.FG93_00842	5.518e-05	49.0	COG4274@1|root,COG4274@2|Bacteria,1RHJ3@1224|Proteobacteria,2U9XS@28211|Alphaproteobacteria,3JZUN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
HKD2_k127_5243797_3	1403313.AXBR01000017_gene3725	1.804e-50	187.0	2DPHP@1|root,32UM5@2|Bacteria,1VBTA@1239|Firmicutes,4HKSX@91061|Bacilli,1ZBMR@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5243797_2	235909.GK1657	9.879e-53	188.0	COG2030@1|root,COG2030@2|Bacteria,1V7QY@1239|Firmicutes,4HJBV@91061|Bacilli,1WGDZ@129337|Geobacillus	91061|Bacilli	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HKD2_k127_5243797_1	1131730.BAVI_16152	3.236e-54	194.0	COG2030@1|root,COG2030@2|Bacteria,1V4PQ@1239|Firmicutes,4HGYW@91061|Bacilli,1ZFZ6@1386|Bacillus	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
HKD2_k127_5243797_0	1403313.AXBR01000017_gene3795	2.437e-63	220.0	COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus	91061|Bacilli	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD2_k127_5248029_22	1132442.KB889752_gene3423	1.492e-09	58.0	29S7Z@1|root,30DCG@2|Bacteria,1UB50@1239|Firmicutes,4IMHI@91061|Bacilli,1ZK63@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248029_21	935836.JAEL01000185_gene1138	4.921e-10	60.0	29T6I@1|root,30ED9@2|Bacteria,1UCEW@1239|Firmicutes,4INX9@91061|Bacilli,1ZP2N@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248029_19	1134413.ANNK01000159_gene3626	1.251e-13	71.0	2A61F@1|root,30UTS@2|Bacteria,1UB8J@1239|Firmicutes,4IMMA@91061|Bacilli,1ZKEM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248029_23	1403313.AXBR01000014_gene2203	1.938e-09	59.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248029_15	1403313.AXBR01000004_gene1631	1.441e-65	227.0	COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,1ZG8Y@1386|Bacillus	91061|Bacilli	S	Belongs to the SprT family	ydcK	-	-	ko:K03095	-	-	-	-	ko00000	-	-	-	SprT-like,Zn_ribbon_SprT
HKD2_k127_5248029_20	634956.Geoth_3697	7.315e-11	63.0	2DRP7@1|root,33CG4@2|Bacteria,1VMHM@1239|Firmicutes,4HRV7@91061|Bacilli,1WH3W@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248029_0	1403313.AXBR01000004_gene1632	0.0	1175.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus	91061|Bacilli	K	COG2183 Transcriptional accessory protein	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HKD2_k127_5248029_14	1403313.AXBR01000004_gene1641	2.515e-67	229.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,1ZG8R@1386|Bacillus	91061|Bacilli	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HKD2_k127_5248029_17	1403313.AXBR01000004_gene1642	4.13e-43	159.0	COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,4HKPU@91061|Bacilli,1ZGYI@1386|Bacillus	91061|Bacilli	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain	ndoAI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
HKD2_k127_5248029_6	1403313.AXBR01000004_gene1643	9.482e-162	517.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus	91061|Bacilli	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.5	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HKD2_k127_5248029_5	1403313.AXBR01000004_gene1644	4.053e-164	521.0	COG2834@1|root,COG2834@2|Bacteria,1TSRE@1239|Firmicutes,4HBCH@91061|Bacilli,1ZBE6@1386|Bacillus	91061|Bacilli	M	COG2834 Outer membrane lipoprotein-sorting protein	ydcC	-	-	-	-	-	-	-	-	-	-	-	DUF4367
HKD2_k127_5248029_26	1294265.JCM21738_1838	0.0009687	42.0	COG4768@1|root,COG4768@2|Bacteria,1UBBB@1239|Firmicutes,4IMQ8@91061|Bacilli,1ZKKT@1386|Bacillus	91061|Bacilli	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
HKD2_k127_5248029_16	1403313.AXBR01000004_gene1645	9.531e-46	167.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,1ZI02@1386|Bacillus	91061|Bacilli	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iYO844.BSU04620	ACPS
HKD2_k127_5248029_11	1403313.AXBR01000004_gene1646	6.289e-79	267.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZCEK@1386|Bacillus	91061|Bacilli	S	membrane protein (homolog of Drosophila rhomboid)	ydcA	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD2_k127_5248029_4	1403313.AXBR01000004_gene1647	1.277e-164	532.0	COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus	91061|Bacilli	S	Membrane	ydbT	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
HKD2_k127_5248029_18	649639.Bcell_1930	8.997e-35	138.0	COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HGMB@91061|Bacilli,1ZG99@1386|Bacillus	91061|Bacilli	S	Bacterial PH domain	ydbS	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
HKD2_k127_5248029_1	1403313.AXBR01000004_gene1649	2.31e-274	849.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
HKD2_k127_5248029_7	1243664.CAVL020000055_gene2558	8.954e-151	489.0	COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,1ZCSR@1386|Bacillus	91061|Bacilli	NT	Protoglobin	hemAT	-	-	ko:K06595	-	-	-	-	ko00000,ko02035	-	-	-	MCPsignal,Protoglobin
HKD2_k127_5248029_2	1403313.AXBR01000004_gene1651	2.823e-207	653.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD2_k127_5248029_3	1347369.CCAD010000020_gene1414	3.287e-171	543.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,1ZDA3@1386|Bacillus	91061|Bacilli	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD2_k127_5248029_25	1385514.N782_03495	1.225e-06	51.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248029_10	1403313.AXBR01000004_gene1653	9.829e-93	311.0	29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,1ZD35@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5248029_9	1403313.AXBR01000004_gene1655	7.222e-106	356.0	COG0845@1|root,COG0845@2|Bacteria,1V5DX@1239|Firmicutes,4HHNP@91061|Bacilli,1ZG1K@1386|Bacillus	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
HKD2_k127_5248029_12	1403313.AXBR01000004_gene1656	3.773e-75	258.0	2DEKV@1|root,32U3N@2|Bacteria,1VDZU@1239|Firmicutes,4HM58@91061|Bacilli,1ZGZW@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
HKD2_k127_5248029_13	1403313.AXBR01000004_gene1658	8.349e-73	255.0	COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli,1ZFND@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yerO	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_5248029_8	1403313.AXBR01000004_gene1659	2.906e-137	445.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus	91061|Bacilli	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD2_k127_5249846_2	1405.DJ92_331	1.243e-79	269.0	COG4843@1|root,COG4843@2|Bacteria,1V79P@1239|Firmicutes,4HMFH@91061|Bacilli,1ZQMW@1386|Bacillus	91061|Bacilli	S	UPF0316 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
HKD2_k127_5249846_1	666686.B1NLA3E_12560	9.827e-80	269.0	COG3773@1|root,COG3773@2|Bacteria,1V3QK@1239|Firmicutes,4HH00@91061|Bacilli,1ZGB9@1386|Bacillus	91061|Bacilli	M	Cell wall	cwlJ	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
HKD2_k127_5249846_0	935836.JAEL01000030_gene3395	1.42e-108	357.0	COG1028@1|root,COG1028@2|Bacteria,1UY2K@1239|Firmicutes,4HCBA@91061|Bacilli,1ZCV0@1386|Bacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD2_k127_5249846_3	1294265.JCM21738_2304	2.508e-22	97.0	2A051@1|root,30N7S@2|Bacteria,1UAQ6@1239|Firmicutes,4IM2V@91061|Bacilli,1ZIY8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5282870_3	1403313.AXBR01000028_gene5013	4.068e-72	245.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus	91061|Bacilli	CE	COG0665 Glycine D-amino acid oxidases (deaminating)	yhfW	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
HKD2_k127_5282870_7	1403313.AXBR01000028_gene5014	5.132e-30	120.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
HKD2_k127_5282870_4	1403313.AXBR01000028_gene5015	6.136e-71	246.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4HH35@91061|Bacilli,1ZGZ6@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF541)	bp26	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
HKD2_k127_5282870_2	1403313.AXBR01000028_gene5017	7.447e-158	501.0	COG0788@1|root,COG0788@2|Bacteria,1TSN4@1239|Firmicutes,4HAW2@91061|Bacilli,1ZAYE@1386|Bacillus	91061|Bacilli	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
HKD2_k127_5282870_9	1385514.N782_03495	1.023e-08	56.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5282870_0	1403313.AXBR01000028_gene5021	0.0	1012.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,4HBN6@91061|Bacilli,1ZCFK@1386|Bacillus	91061|Bacilli	J	COG0008 Glutamyl- and glutaminyl-tRNA synthetases	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HKD2_k127_5282870_8	1122927.KB895412_gene735	7.747e-17	81.0	2C4KX@1|root,2ZBU2@2|Bacteria,1V1FE@1239|Firmicutes,4HFQR@91061|Bacilli,2719E@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HKD2_k127_5282870_6	1396.DJ87_3051	5.31e-32	128.0	2C4KX@1|root,2ZBU2@2|Bacteria,1V1FE@1239|Firmicutes,4HFQR@91061|Bacilli,1ZCVR@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HKD2_k127_5282870_5	1461580.CCAS010000066_gene3983	9.934e-36	138.0	COG1595@1|root,COG1595@2|Bacteria,1V64Z@1239|Firmicutes,4HG16@91061|Bacilli,1ZFRR@1386|Bacillus	91061|Bacilli	K	RNA polymerase	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_5282870_1	1396.DJ87_1563	3.465e-242	756.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,1ZD0J@1386|Bacillus	91061|Bacilli	G	Belongs to the FGGY kinase family	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
HKD2_k127_531647_2	1403313.AXBR01000025_gene5006	2.674e-185	582.0	COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,4HAQP@91061|Bacilli,1ZBIY@1386|Bacillus	91061|Bacilli	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
HKD2_k127_531647_1	1403313.AXBR01000025_gene5007	2.155e-253	786.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
HKD2_k127_531647_0	1403313.AXBR01000025_gene5008	0.0	1512.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD2_k127_531647_3	796606.BMMGA3_00545	3.059e-168	534.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,1ZBJU@1386|Bacillus	91061|Bacilli	E	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity	mcsB	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
HKD2_k127_531647_4	1403313.AXBR01000025_gene5010	1.072e-87	292.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus	91061|Bacilli	S	protein with conserved CXXC pairs	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
HKD2_k127_531647_5	1403313.AXBR01000025_gene5011	1.922e-76	258.0	COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,1ZFR6@1386|Bacillus	91061|Bacilli	K	Belongs to the CtsR family	ctsR	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03708	-	-	-	-	ko00000,ko03000	-	-	-	CtsR
HKD2_k127_5322332_6	1217715.F994_01871	1.108e-13	72.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,3NJVY@468|Moraxellaceae	1236|Gammaproteobacteria	S	Competence protein ComEC	ycaI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HKD2_k127_5322332_1	686340.Metal_0008	3.48e-70	241.0	COG3293@1|root,COG3293@2|Bacteria,1R9X8@1224|Proteobacteria,1S3IC@1236|Gammaproteobacteria,1XGBB@135618|Methylococcales	135618|Methylococcales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HKD2_k127_5322332_4	1123487.KB892842_gene4142	1.006e-27	115.0	COG3293@1|root,COG3293@2|Bacteria,1N3I7@1224|Proteobacteria,2VU9M@28216|Betaproteobacteria,2KZ97@206389|Rhodocyclales	206389|Rhodocyclales	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
HKD2_k127_5322332_3	1217658.F987_04446	1.224e-39	147.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,3NIQD@468|Moraxellaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
HKD2_k127_5322332_5	575588.ACPN01000197_gene1710	8.162e-23	99.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,3NIQD@468|Moraxellaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
HKD2_k127_5322332_0	202956.BBNL01000100_gene2504	2.571e-81	272.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,3NIQD@468|Moraxellaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
HKD2_k127_5322332_2	525244.HMPREF0023_3204	6.225e-59	205.0	COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,1SEAC@1236|Gammaproteobacteria,3NNND@468|Moraxellaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
HKD2_k127_5322332_7	40373.F991_02186	2.37e-07	53.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1S1UK@1236|Gammaproteobacteria,3NMDG@468|Moraxellaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_3,GST_N
HKD2_k127_533480_10	1395587.P364_0126045	2.392e-18	84.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,26R56@186822|Paenibacillaceae	91061|Bacilli	I	phospholipid phosphatase	pgpB3	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_533480_6	1408303.JNJJ01000085_gene2623	1.262e-45	167.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZIEP@1386|Bacillus	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	pgpB3	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_533480_2	1123405.AUMM01000029_gene1571	1.338e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,4HAX9@91061|Bacilli	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_533480_1	1340434.AXVA01000004_gene2693	8.318e-185	589.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,4HDDP@91061|Bacilli,1ZC2G@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	yycG_2	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_533480_0	1340434.AXVA01000004_gene2682	1.627e-208	653.0	COG4705@1|root,COG4705@2|Bacteria,1UYKG@1239|Firmicutes,4HEIH@91061|Bacilli,1ZF44@1386|Bacillus	91061|Bacilli	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
HKD2_k127_533480_9	1340434.AXVA01000003_gene2575	3.56e-23	100.0	COG4705@1|root,COG4705@2|Bacteria,1U1EC@1239|Firmicutes,4HHM4@91061|Bacilli,1ZRV9@1386|Bacillus	91061|Bacilli	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
HKD2_k127_533480_5	357809.Cphy_0672	1.494e-49	183.0	COG1309@1|root,COG1309@2|Bacteria,1UH5U@1239|Firmicutes,249A2@186801|Clostridia,22155@1506553|Lachnoclostridium	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
HKD2_k127_533480_8	357809.Cphy_0673	4.569e-35	144.0	COG1266@1|root,COG1266@2|Bacteria,1VB4D@1239|Firmicutes,24TCA@186801|Clostridia	186801|Clostridia	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD2_k127_533480_13	471223.GWCH70_3181	3.827e-09	59.0	2BUHN@1|root,32PTT@2|Bacteria,1V9SH@1239|Firmicutes,4HJ6P@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HKD2_k127_533480_4	1461580.CCAS010000035_gene3020	2.947e-50	185.0	2DUZZ@1|root,32UY8@2|Bacteria,1VAX8@1239|Firmicutes,4HMKW@91061|Bacilli,1ZF86@1386|Bacillus	91061|Bacilli	-	-	yobW	-	-	-	-	-	-	-	-	-	-	-	DUF1453
HKD2_k127_533480_3	1117379.BABA_03434	9.546e-71	240.0	COG0491@1|root,COG0491@2|Bacteria,1UZGY@1239|Firmicutes,4HBDD@91061|Bacilli,1ZQQI@1386|Bacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_533480_7	1227360.C176_06877	3.157e-43	159.0	COG0491@1|root,COG0491@2|Bacteria,1UZGY@1239|Firmicutes,4HBDD@91061|Bacilli,26DY8@186818|Planococcaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_5347953_4	1403313.AXBR01000002_gene4409	3.751e-123	398.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD2_k127_5347953_1	1403313.AXBR01000002_gene4408	4.74e-188	591.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,1ZCVI@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD2_k127_5347953_8	1385514.N782_03495	4.14e-10	61.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5347953_0	1403313.AXBR01000002_gene4407	1.576e-188	591.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H9KJ@91061|Bacilli,1ZCIZ@1386|Bacillus	91061|Bacilli	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
HKD2_k127_5347953_5	1122918.KB907256_gene2351	2.392e-90	312.0	COG0726@1|root,COG0726@2|Bacteria,1V0YE@1239|Firmicutes,4HFKC@91061|Bacilli,26TIM@186822|Paenibacillaceae	91061|Bacilli	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HKD2_k127_5347953_6	1211035.CD30_17290	2.384e-60	216.0	2A5JQ@1|root,30UA1@2|Bacteria,1V4UE@1239|Firmicutes,4HH82@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5347953_3	1403313.AXBR01000002_gene4401	8.226e-127	408.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4HAVS@91061|Bacilli,1ZC7N@1386|Bacillus	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD2_k127_5347953_2	1403313.AXBR01000002_gene4400	9.335e-135	435.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HE64@91061|Bacilli,1ZBUM@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_5357658_11	1211814.CAPG01000076_gene3580	7.082e-10	61.0	COG1655@1|root,COG1655@2|Bacteria,1UY0V@1239|Firmicutes,4HDH4@91061|Bacilli,1ZD58@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
HKD2_k127_5357658_10	1499680.CCFE01000011_gene383	1.782e-29	118.0	COG4844@1|root,COG4844@2|Bacteria,1VFJJ@1239|Firmicutes,4HNQ8@91061|Bacilli,1ZHVJ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0349 family	yuzB	-	-	-	-	-	-	-	-	-	-	-	DUF1450
HKD2_k127_5357658_2	1174504.AJTN02000200_gene3545	3.888e-185	584.0	COG1252@1|root,COG1252@2|Bacteria,1TPE6@1239|Firmicutes,4H9MY@91061|Bacilli,1ZC0V@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	yutJ	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD2_k127_5357658_8	1403313.AXBR01000013_gene1449	2.822e-46	169.0	COG4837@1|root,COG4837@2|Bacteria,1VA2D@1239|Firmicutes,4HKZN@91061|Bacilli,1ZI07@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuzD	-	-	-	-	-	-	-	-	-	-	-	DUF1462
HKD2_k127_5357658_9	1403313.AXBR01000013_gene1448	2.384e-40	150.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,1ZHTR@1386|Bacillus	91061|Bacilli	O	COG0694 Thioredoxin-like proteins and domains	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
HKD2_k127_5357658_3	1403313.AXBR01000013_gene1446	6.051e-153	488.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,1ZBK1@1386|Bacillus	91061|Bacilli	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD2_k127_5357658_1	1403313.AXBR01000013_gene1445	4.46e-192	602.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,1ZB11@1386|Bacillus	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32250	PALP
HKD2_k127_5357658_0	1403313.AXBR01000013_gene1444	8.39e-220	687.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZAVJ@1386|Bacillus	91061|Bacilli	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06610	ACT,Homoserine_dh,NAD_binding_3
HKD2_k127_5357658_6	1403313.AXBR01000013_gene1443	1.102e-95	322.0	COG3786@1|root,COG3786@2|Bacteria,1VA00@1239|Firmicutes,4HH8T@91061|Bacilli,1ZD3J@1386|Bacillus	91061|Bacilli	F	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,SH3_3,YkuD
HKD2_k127_5357658_4	1403313.AXBR01000013_gene1442	4.892e-147	473.0	COG2334@1|root,COG2334@2|Bacteria,1VEZ6@1239|Firmicutes,4HBAB@91061|Bacilli,1ZBAM@1386|Bacillus	91061|Bacilli	S	Spore coat protein	yutH	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5357658_7	1403313.AXBR01000013_gene1441	3.791e-82	275.0	COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,1ZFQE@1386|Bacillus	91061|Bacilli	I	COG1267 Phosphatidylglycerophosphatase A and related proteins	yutG	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
HKD2_k127_5357658_5	935836.JAEL01000095_gene3280	1.031e-124	403.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,1ZB73@1386|Bacillus	91061|Bacilli	G	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro	nagD	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
HKD2_k127_5359286_0	1196323.ALKF01000188_gene4867	2.112e-39	159.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26QU5@186822|Paenibacillaceae	91061|Bacilli	NT	chemotaxis protein	mcpB1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
HKD2_k127_5359286_1	1121289.JHVL01000001_gene1996	4.275e-12	70.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
HKD2_k127_5359286_2	1121085.AUCI01000001_gene3681	9.322e-11	67.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	mcpB1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
HKD2_k127_5367542_10	1403313.AXBR01000014_gene2210	2.125e-37	141.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus	91061|Bacilli	H	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5367542_0	1174504.AJTN02000176_gene2059	9.018e-164	522.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus	91061|Bacilli	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30780	MR_MLE_C,MR_MLE_N
HKD2_k127_5367542_15	665959.HMPREF1013_02693	2.844e-12	67.0	2E3H2@1|root,32YFR@2|Bacteria,1VF0S@1239|Firmicutes,4HNTB@91061|Bacilli,1ZJ4H@1386|Bacillus	91061|Bacilli	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HKD2_k127_5367542_5	1403313.AXBR01000014_gene2216	7.696e-130	421.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HKD2_k127_5367542_11	574376.BAMA_11785	6.032e-37	139.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,1ZHVV@1386|Bacillus	91061|Bacilli	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD2_k127_5367542_7	634956.Geoth_0734	2.162e-80	269.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,1WFTH@129337|Geobacillus	91061|Bacilli	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
HKD2_k127_5367542_17	935837.JAEK01000035_gene2925	0.0004226	45.0	2EPBZ@1|root,33GYQ@2|Bacteria,1VKHA@1239|Firmicutes,4HRUT@91061|Bacilli,1ZK7S@1386|Bacillus	91061|Bacilli	S	Tumour necrosis factor receptor superfamily member 19	-	-	-	-	-	-	-	-	-	-	-	-	RELT
HKD2_k127_5367542_9	1403313.AXBR01000014_gene2223	4.382e-50	179.0	2CYE0@1|root,32E8M@2|Bacteria,1V6HF@1239|Firmicutes,4HJJG@91061|Bacilli,1ZI8T@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5367542_8	1174504.AJTN02000176_gene2049	7.344e-56	199.0	COG0494@1|root,COG0494@2|Bacteria,1V42H@1239|Firmicutes,4HH5W@91061|Bacilli,1ZGYP@1386|Bacillus	91061|Bacilli	L	Belongs to the Nudix hydrolase family	ytkD	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD2_k127_5367542_13	1449343.JQLQ01000002_gene107	2.05e-24	103.0	2DR1Y@1|root,339TZ@2|Bacteria,1VK7M@1239|Firmicutes,4HR6A@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3006)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3006
HKD2_k127_5367542_3	1403313.AXBR01000023_gene2386	1.629e-130	421.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus	91061|Bacilli	L	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Lactamase_B,SLH
HKD2_k127_5367542_4	1403313.AXBR01000014_gene2225	6.573e-130	419.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HARB@91061|Bacilli,1ZD96@1386|Bacillus	91061|Bacilli	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	ytlD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD2_k127_5367542_6	221109.22778002	1.069e-86	293.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HBZ6@91061|Bacilli,23JF6@182709|Oceanobacillus	91061|Bacilli	P	ATPases associated with a variety of cellular activities	ytlC	-	3.6.3.36	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00435,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4	-	-	ABC_tran
HKD2_k127_5367542_1	1403313.AXBR01000014_gene2227	1.163e-160	511.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,1ZC0Z@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	ytlA	GO:0003674,GO:0005215	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
HKD2_k127_5367542_14	1499684.CCNP01000019_gene2223	6.439e-15	76.0	2CEUM@1|root,2ZDXX@2|Bacteria,1W21E@1239|Firmicutes,24TF1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5367542_2	1403313.AXBR01000018_gene3583	4.656e-154	491.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus	91061|Bacilli	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	yeaB	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD2_k127_5386098_6	1403313.AXBR01000002_gene4124	2.016e-48	177.0	COG0589@1|root,COG0589@2|Bacteria,1V6RY@1239|Firmicutes,4HIZM@91061|Bacilli,1ZHCT@1386|Bacillus	91061|Bacilli	T	Belongs to the universal stress protein A family	nhaX	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD2_k127_5386098_2	1403313.AXBR01000002_gene4125	5.093e-143	458.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,1ZBXV@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ywbI	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_5386098_5	1403313.AXBR01000002_gene4126	3.062e-52	188.0	2E3CY@1|root,32YC7@2|Bacteria,1VGK5@1239|Firmicutes,4HPSI@91061|Bacilli,1ZJEC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5386098_3	1403313.AXBR01000002_gene4130	2.874e-137	444.0	COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,1ZBJD@1386|Bacillus	91061|Bacilli	S	AI-2E family transporter	ydbI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD2_k127_5386098_7	1403313.AXBR01000002_gene4132	5.592e-33	128.0	COG0166@1|root,COG0166@2|Bacteria,1VFQ2@1239|Firmicutes,4HNRS@91061|Bacilli,1ZIWJ@1386|Bacillus	91061|Bacilli	G	Helix-turn-helix domain	yoeD	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HKD2_k127_5386098_10	1340434.AXVA01000010_gene5484	2.443e-05	47.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5386098_1	1403313.AXBR01000002_gene4454	1.58e-185	586.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,1ZATR@1386|Bacillus	91061|Bacilli	P	Belongs to the TelA family	yaaN	-	-	-	-	-	-	-	-	-	-	-	TelA
HKD2_k127_5386098_4	1403313.AXBR01000002_gene4455	9.566e-70	243.0	COG4915@1|root,COG4915@2|Bacteria,1V5B1@1239|Firmicutes,4HKAX@91061|Bacilli,1ZG4A@1386|Bacillus	91061|Bacilli	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	xpaC	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
HKD2_k127_5386098_11	1403313.AXBR01000021_gene2985	0.0002405	44.0	COG3290@1|root,COG3290@2|Bacteria,1TQHC@1239|Firmicutes,4HAH4@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,SPOB_a
HKD2_k127_5386098_0	1403313.AXBR01000002_gene4458	7.601e-229	713.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus	91061|Bacilli	P	Ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,MCPsignal
HKD2_k127_5386098_8	666686.B1NLA3E_09030	1.295e-32	130.0	29J4G@1|root,3061X@2|Bacteria,1TZ1P@1239|Firmicutes,4I88A@91061|Bacilli,1ZJRY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5386098_9	1340434.AXVA01000016_gene701	3.69e-14	72.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5389591_3	1423321.AS29_18525	2.059e-72	251.0	COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus	91061|Bacilli	P	COG0672 High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
HKD2_k127_5389591_0	315730.BcerKBAB4_1651	1.481e-146	475.0	COG2733@1|root,COG2733@2|Bacteria,1TS8F@1239|Firmicutes,4HC8U@91061|Bacilli,1ZCND@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD2_k127_5389591_4	315730.BcerKBAB4_5662	9.081e-62	219.0	COG0741@1|root,COG0741@2|Bacteria,1VD4A@1239|Firmicutes,4HN7R@91061|Bacilli,1ZDE7@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yocA	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
HKD2_k127_5389591_2	796606.BMMGA3_09740	4.94e-84	285.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli,1ZBYZ@1386|Bacillus	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD2_k127_5389591_1	1405.DJ92_4418	3.899e-121	392.0	COG3384@1|root,COG3384@2|Bacteria,1TSRZ@1239|Firmicutes,4HAAN@91061|Bacilli,1ZBC3@1386|Bacillus	91061|Bacilli	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	DODA	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
HKD2_k127_5389591_5	1131730.BAVI_17162	6.381e-05	46.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
HKD2_k127_5403516_1	1403313.AXBR01000009_gene780	9.401e-141	451.0	COG0189@1|root,COG0189@2|Bacteria,1TWCJ@1239|Firmicutes,4HB5J@91061|Bacilli,1ZQTC@1386|Bacillus	91061|Bacilli	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	lysX_2	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
HKD2_k127_5403516_3	1403313.AXBR01000009_gene781	6.975e-115	376.0	COG0189@1|root,COG0189@2|Bacteria,1UYT6@1239|Firmicutes,4HE6U@91061|Bacilli,1ZFTD@1386|Bacillus	91061|Bacilli	HJ	RimK-like ATP-grasp domain	lysX_1	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
HKD2_k127_5403516_2	1089439.KB902252_gene1438	8.036e-130	429.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,463IC@72273|Thiotrichales	72273|Thiotrichales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD2_k127_5403516_4	997296.PB1_03855	3.716e-33	135.0	2ES56@1|root,33JPZ@2|Bacteria,1U2H0@1239|Firmicutes,4IM8G@91061|Bacilli,1ZJGI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5403516_0	997296.PB1_03860	7.375e-147	467.0	COG3733@1|root,COG3733@2|Bacteria,1TY2K@1239|Firmicutes,4I75Q@91061|Bacilli,1ZC7C@1386|Bacillus	91061|Bacilli	Q	Copper amine oxidase, enzyme domain	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
HKD2_k127_5413782_3	1499680.CCFE01000021_gene1782	1.727e-16	79.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HKD2_k127_5413782_1	1211814.CAPG01000036_gene1842	2.128e-86	290.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,1ZE5P@1386|Bacillus	91061|Bacilli	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD2_k127_5413782_0	1403313.AXBR01000007_gene373	2.552e-204	640.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,1ZARR@1386|Bacillus	91061|Bacilli	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HKD2_k127_5413782_5	1385514.N782_03495	1.741e-06	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5413782_4	1196324.A374_03349	1.081e-11	65.0	2EHPS@1|root,33BFI@2|Bacteria,1VM1E@1239|Firmicutes,4HS3S@91061|Bacilli	91061|Bacilli	S	YpzI-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YpzI
HKD2_k127_5413782_2	1403313.AXBR01000007_gene371	4.674e-40	152.0	2C369@1|root,32TN5@2|Bacteria,1VDHE@1239|Firmicutes,4HN2A@91061|Bacilli,1ZDBJ@1386|Bacillus	91061|Bacilli	-	-	yphA	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5418291_0	1403313.AXBR01000022_gene2715	4.618e-285	884.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,1ZD3W@1386|Bacillus	91061|Bacilli	E	oligoendopeptidase	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
HKD2_k127_5418291_2	574376.BAMA_20610	8.242e-82	284.0	2DBJ5@1|root,2Z9IG@2|Bacteria,1VIXW@1239|Firmicutes,4HPR1@91061|Bacilli,1ZB1A@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5418291_3	1403313.AXBR01000022_gene2716	2.831e-72	245.0	COG1846@1|root,COG1846@2|Bacteria,1V6EE@1239|Firmicutes,4HJ8T@91061|Bacilli,1ZGC6@1386|Bacillus	91061|Bacilli	K	transcriptional	ykvE	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
HKD2_k127_5418291_1	1403313.AXBR01000022_gene2718	2.303e-179	569.0	COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4HA7C@91061|Bacilli,1ZB21@1386|Bacillus	91061|Bacilli	P	COG0477 Permeases of the major facilitator superfamily	fsr	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
HKD2_k127_5421073_1	935836.JAEL01000089_gene5238	6.321e-45	164.0	COG4838@1|root,COG4838@2|Bacteria,1VAXB@1239|Firmicutes,4HKIX@91061|Bacilli,1ZI2B@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0358 family	ylaN	-	-	-	-	-	-	-	-	-	-	-	DUF1507
HKD2_k127_5421073_0	1403313.AXBR01000021_gene3214	0.0	2000.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus	91061|Bacilli	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
HKD2_k127_5425370_1	997296.PB1_16069	1.034e-27	114.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HUAQ@91061|Bacilli,1ZREM@1386|Bacillus	91061|Bacilli	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD2_k127_5425370_3	1385512.N784_01550	6.665e-10	59.0	COG2197@1|root,COG2197@2|Bacteria,1VBZR@1239|Firmicutes,4HKT4@91061|Bacilli,2YAU6@289201|Pontibacillus	91061|Bacilli	K	LuxR family transcriptional regulator	gerE	-	-	ko:K01994	-	-	-	-	ko00000,ko03000	-	-	-	GerE
HKD2_k127_5425370_0	1403313.AXBR01000009_gene825	4.24e-132	425.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,1ZBC9@1386|Bacillus	91061|Bacilli	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU28390	Asp_Glu_race
HKD2_k127_5425370_2	1403313.AXBR01000009_gene824	2.365e-26	110.0	COG5401@1|root,COG5401@2|Bacteria,1TPQD@1239|Firmicutes,4HB1S@91061|Bacilli,1ZBZJ@1386|Bacillus	91061|Bacilli	S	COG5401 Spore germination protein	gerM	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
HKD2_k127_5426359_2	1403313.AXBR01000007_gene354	6.045e-15	76.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,1ZC9C@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD2_k127_5426359_0	1403313.AXBR01000007_gene355	1.804e-227	707.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,1ZB2N@1386|Bacillus	91061|Bacilli	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HKD2_k127_5426359_1	1403313.AXBR01000007_gene356	1.172e-63	220.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,4HAS1@91061|Bacilli,1ZCKU@1386|Bacillus	91061|Bacilli	NT	COG1352 Methylase of chemotaxis methyl-accepting proteins	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
HKD2_k127_5428613_1	1196029.ALIM01000030_gene814	3.96e-48	175.0	COG1366@1|root,COG1366@2|Bacteria,1V1QF@1239|Firmicutes,4HGBT@91061|Bacilli,1ZDJX@1386|Bacillus	91061|Bacilli	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	STAS
HKD2_k127_5428613_0	666686.B1NLA3E_00895	5.938e-112	364.0	COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus	91061|Bacilli	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
HKD2_k127_5431723_1	1174504.AJTN02000220_gene1350	8.593e-50	180.0	2CC31@1|root,2Z920@2|Bacteria,1UZSZ@1239|Firmicutes,4HCVB@91061|Bacilli,1ZGJ7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5431723_2	1294265.JCM21738_931	4.201e-48	178.0	COG0492@1|root,COG0492@2|Bacteria,1V9JY@1239|Firmicutes,4HIPN@91061|Bacilli	91061|Bacilli	O	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Pyr_redox_2
HKD2_k127_5431723_0	649747.HMPREF0083_01383	3.516e-101	334.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,275PE@186822|Paenibacillaceae	91061|Bacilli	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
HKD2_k127_5431723_3	935836.JAEL01000014_gene2063	3.707e-41	156.0	29UM7@1|root,30FYQ@2|Bacteria,1UA1E@1239|Firmicutes,4IKA5@91061|Bacilli,1ZG42@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5431723_4	1403313.AXBR01000007_gene251	2.402e-40	155.0	COG1559@1|root,COG1559@2|Bacteria,1TX6D@1239|Firmicutes,4IKF7@91061|Bacilli,1ZGTZ@1386|Bacillus	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5431723_5	1403313.AXBR01000002_gene4148	0.0002559	44.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus	91061|Bacilli	E	Aminotransferase	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_5434428_2	1403313.AXBR01000021_gene3109	2.956e-159	508.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD2_k127_5434428_1	1403313.AXBR01000021_gene3108	4.446e-180	568.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,1ZB46@1386|Bacillus	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD2_k127_5434428_10	1403313.AXBR01000021_gene3106	5.936e-52	186.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,1ZH7Z@1386|Bacillus	91061|Bacilli	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
HKD2_k127_5434428_0	1403313.AXBR01000021_gene3105	7.156e-216	672.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,1ZB4I@1386|Bacillus	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD2_k127_5434428_12	1033734.CAET01000018_gene695	2.558e-33	129.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,1ZB4I@1386|Bacillus	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD2_k127_5434428_14	1027292.HMPREF9372_0669	0.0009645	43.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,26FCD@186818|Planococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD2_k127_5434428_11	1117379.BABA_23900	2.847e-47	171.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,1ZGXP@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD2_k127_5434428_13	1403313.AXBR01000021_gene3103	8.47e-33	128.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,1ZIW7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
HKD2_k127_5434428_9	1403313.AXBR01000021_gene3102	3.131e-58	205.0	2BIN4@1|root,32CV6@2|Bacteria,1VC14@1239|Firmicutes,4HJYF@91061|Bacilli,1ZGYX@1386|Bacillus	91061|Bacilli	S	YlqD protein	-	-	-	-	-	-	-	-	-	-	-	-	YlqD
HKD2_k127_5434428_7	1403313.AXBR01000021_gene3101	3.283e-78	264.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,1ZFP2@1386|Bacillus	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HKD2_k127_5434428_4	1403313.AXBR01000021_gene3100	2.399e-136	436.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HKD2_k127_5434428_8	1034347.CAHJ01000010_gene2095	3.091e-63	218.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,1ZGDK@1386|Bacillus	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HKD2_k127_5434428_6	1403313.AXBR01000021_gene3098	1.419e-84	287.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZRQR@1386|Bacillus	91061|Bacilli	U	Belongs to the peptidase S26 family	sipS	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD2_k127_5434428_3	1403313.AXBR01000021_gene3097	5.208e-157	499.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,1ZB63@1386|Bacillus	91061|Bacilli	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	rbgA	GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HKD2_k127_5434428_5	1403313.AXBR01000021_gene3096	6.679e-118	386.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD2_k127_5437839_1	1307436.PBF_23974	4.737e-231	721.0	COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus	91061|Bacilli	C	oxidase, subunit	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
HKD2_k127_5437839_4	1196031.ALEG01000067_gene4756	3.385e-164	522.0	COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus	91061|Bacilli	C	COG1294 Cytochrome bd-type quinol oxidase, subunit 2	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
HKD2_k127_5437839_14	1380408.AVGH01000046_gene2803	0.0009165	42.0	COG1961@1|root,COG1961@2|Bacteria,1UZT3@1239|Firmicutes,4HCR8@91061|Bacilli	91061|Bacilli	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	binR	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
HKD2_k127_5437839_11	1285586.H131_17736	5.993e-11	64.0	2EJJB@1|root,2ZWPB@2|Bacteria,1W3U7@1239|Firmicutes,4I23W@91061|Bacilli,3IYYA@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5437839_8	886882.PPSC2_p0413	8.597e-41	159.0	COG3831@1|root,COG3831@2|Bacteria	2|Bacteria	-	-	-	-	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	DUF4240,PARP,WGR
HKD2_k127_5437839_2	1220589.CD32_04710	9.729e-192	603.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,3IVP2@400634|Lysinibacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_5437839_6	698769.JFBD01000019_gene2079	5.611e-75	256.0	COG1309@1|root,COG1309@2|Bacteria,1V7KP@1239|Firmicutes,4HIQG@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
HKD2_k127_5437839_0	1347369.CCAD010000056_gene4251	1.503e-240	752.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5437839_10	1121472.AQWN01000003_gene1370	8.576e-14	70.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,263R6@186807|Peptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD2_k127_5437839_3	649747.HMPREF0083_04583	1.802e-185	586.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,26RP3@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_5437839_13	224325.AF_0285	0.00073	44.0	COG1250@1|root,arCOG00249@2157|Archaea,2XT6B@28890|Euryarchaeota,245SW@183980|Archaeoglobi	183980|Archaeoglobi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17	ko:K15016	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00374,M00375	R01975,R03026	RC00117,RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HKD2_k127_5437839_9	1117379.BABA_20116	1.044e-23	102.0	2E0UC@1|root,32WBV@2|Bacteria,1VDJ2@1239|Firmicutes,4HKXT@91061|Bacilli,1ZJ5C@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2533)	ypbS	-	-	-	-	-	-	-	-	-	-	-	DUF2533
HKD2_k127_5437839_7	360911.EAT1b_2176	2.685e-67	234.0	COG0457@1|root,COG0457@2|Bacteria,1UJRM@1239|Firmicutes,4ITEJ@91061|Bacilli	91061|Bacilli	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
HKD2_k127_5437839_5	1196324.A374_03994	4.111e-139	451.0	COG4974@1|root,COG4974@2|Bacteria,1VRBN@1239|Firmicutes,4HUDG@91061|Bacilli	91061|Bacilli	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_5438426_1	1120973.AQXL01000135_gene1332	1.166e-183	582.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli	91061|Bacilli	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
HKD2_k127_5438426_2	1120973.AQXL01000135_gene1329	1.841e-84	286.0	COG4565@1|root,COG4565@2|Bacteria,1V49R@1239|Firmicutes,4IQDF@91061|Bacilli	91061|Bacilli	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,Response_reg
HKD2_k127_5438426_0	646529.Desaci_3984	1.449e-192	615.0	COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,247YE@186801|Clostridia,264QG@186807|Peptococcaceae	186801|Clostridia	T	Signal transduction histidine kinase regulating citrate malate	citS	-	2.7.13.3	ko:K02476,ko:K11614,ko:K11691	ko02020,map02020	M00489,M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,PAS_10,SPOB_a,sCache_3_2
HKD2_k127_5442047_6	1403313.AXBR01000021_gene3226	1.171e-06	52.0	2DPF7@1|root,331TZ@2|Bacteria,1VEDX@1239|Firmicutes,4HPQF@91061|Bacilli,1ZK0B@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5325
HKD2_k127_5442047_0	1211814.CAPG01000038_gene2247	0.0	1082.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,1ZB9R@1386|Bacillus	91061|Bacilli	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
HKD2_k127_5442047_4	1403313.AXBR01000021_gene3224	1.977e-47	171.0	2E309@1|root,32TAR@2|Bacteria,1VBNE@1239|Firmicutes,4HM33@91061|Bacilli,1ZI2F@1386|Bacillus	91061|Bacilli	S	YlaH-like protein	ylaH	-	-	-	-	-	-	-	-	-	-	-	YlaH
HKD2_k127_5442047_5	1403313.AXBR01000021_gene3219	1.223e-29	118.0	COG4896@1|root,COG4896@2|Bacteria,1VFMW@1239|Firmicutes,4HNPM@91061|Bacilli,1ZIXV@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ylaI	-	-	-	-	-	-	-	-	-	-	-	DUF2197
HKD2_k127_5442047_3	1174504.AJTN02000218_gene3114	4.008e-60	213.0	2A3AP@1|root,30RSQ@2|Bacteria,1VA69@1239|Firmicutes,4HKTQ@91061|Bacilli,1ZFXZ@1386|Bacillus	91061|Bacilli	S	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)	ylaJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YhcN_YlaJ
HKD2_k127_5442047_1	1403313.AXBR01000021_gene3217	9.683e-246	763.0	COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus	91061|Bacilli	T	ATPase related to phosphate starvation-inducible protein PhoH	ylaK	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
HKD2_k127_5442047_2	1403313.AXBR01000021_gene3216	2.113e-67	235.0	COG2041@1|root,COG2041@2|Bacteria,1V1EZ@1239|Firmicutes,4HIWI@91061|Bacilli,1ZDPV@1386|Bacillus	91061|Bacilli	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	ylaL	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5486095_3	1340434.AXVA01000017_gene4202	9.055e-27	109.0	COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,1ZGHR@1386|Bacillus	91061|Bacilli	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD2_k127_5486095_1	1121090.KB894699_gene4134	4.063e-143	459.0	COG0346@1|root,COG0346@2|Bacteria,1TQCN@1239|Firmicutes,4HAMC@91061|Bacilli,1ZAQY@1386|Bacillus	91061|Bacilli	E	COG0346 Lactoylglutathione lyase and related lyases	ydfO	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD2_k127_5486095_0	1423321.AS29_04790	1.563e-144	465.0	COG0346@1|root,COG0346@2|Bacteria,1TQCN@1239|Firmicutes,4HAMC@91061|Bacilli,1ZF0K@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	mhqO	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD2_k127_5486095_2	1347086.CCBA010000005_gene4033	5.954e-93	308.0	COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,1ZAQZ@1386|Bacillus	91061|Bacilli	S	Carboxylesterase	yahD	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,DLH
HKD2_k127_5491533_1	1403313.AXBR01000008_gene736	5.485e-107	350.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HKD2_k127_5491533_2	1403313.AXBR01000008_gene735	1.042e-40	153.0	2E6NG@1|root,3318Y@2|Bacteria,1VHES@1239|Firmicutes,4HP4D@91061|Bacilli	91061|Bacilli	S	Post-transcriptional regulator	yrzD	-	-	-	-	-	-	-	-	-	-	-	Post_transc_reg
HKD2_k127_5491533_0	1403313.AXBR01000008_gene734	1.531e-256	800.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD2_k127_5502463_3	1340434.AXVA01000010_gene5484	2.897e-06	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5502463_2	1132442.KB889752_gene841	1.585e-96	319.0	COG1309@1|root,COG1309@2|Bacteria,1V2DH@1239|Firmicutes,4HFVR@91061|Bacilli,1ZRDE@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
HKD2_k127_5502463_1	345219.Bcoa_1870	4.813e-220	686.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1ZCGC@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	yngJ	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_5502463_0	665952.HMPREF1015_01128	1.101e-234	731.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1ZPZR@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	yngI	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5503678_0	935836.JAEL01000013_gene4513	3.543e-210	660.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZEE8@1386|Bacillus	91061|Bacilli	S	Permease family	xprA	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HKD2_k127_5503678_2	1307436.PBF_20683	2.458e-34	134.0	COG1975@1|root,COG1975@2|Bacteria,1VFRE@1239|Firmicutes,4IKUK@91061|Bacilli,1ZHNN@1386|Bacillus	91061|Bacilli	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
HKD2_k127_5503678_1	935836.JAEL01000013_gene4515	1.312e-73	252.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4HEI3@91061|Bacilli,1ZD2G@1386|Bacillus	91061|Bacilli	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HKD2_k127_5516081_2	666686.B1NLA3E_05235	4.131e-14	74.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,1ZFHT@1386|Bacillus	91061|Bacilli	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD2_k127_5516081_4	1033734.CAET01000058_gene1906	1.151e-05	53.0	29R6C@1|root,30C7Q@2|Bacteria,1U9C7@1239|Firmicutes,4IJF4@91061|Bacilli,1ZK3G@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5516081_1	1347369.CCAD010000013_gene2552	1.854e-28	125.0	2E69W@1|root,330XT@2|Bacteria,1VFAJ@1239|Firmicutes,4HQVI@91061|Bacilli,1ZIB6@1386|Bacillus	91061|Bacilli	S	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
HKD2_k127_5516081_0	1403313.AXBR01000010_gene1160	0.0	1341.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus	91061|Bacilli	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD2_k127_5516081_3	656519.Halsa_1436	6.974e-08	65.0	COG4972@1|root,COG4972@2|Bacteria,1V19I@1239|Firmicutes,25DJ0@186801|Clostridia,3WAT5@53433|Halanaerobiales	186801|Clostridia	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
HKD2_k127_5561683_1	1174504.AJTN02000262_gene662	1.504e-129	414.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,1ZAV8@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD2_k127_5561683_4	1403313.AXBR01000008_gene582	1.307e-32	136.0	2E87Y@1|root,332M1@2|Bacteria,1VHQ0@1239|Firmicutes,4HNRH@91061|Bacilli,1ZJI7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5561683_3	1403313.AXBR01000008_gene581	2.876e-45	167.0	COG2010@1|root,COG2010@2|Bacteria,1VA0V@1239|Firmicutes,4HKF3@91061|Bacilli,1ZHVP@1386|Bacillus	91061|Bacilli	C	COG2010 Cytochrome c, mono- and diheme variants	cccA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
HKD2_k127_5561683_2	1403313.AXBR01000008_gene580	9.081e-101	332.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,1ZE5B@1386|Bacillus	91061|Bacilli	S	SAM-dependent methyltransferase	trmK	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TrmK
HKD2_k127_5561683_0	1403313.AXBR01000008_gene579	4.085e-196	616.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus	91061|Bacilli	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
HKD2_k127_5579427_1	1123371.ATXH01000036_gene1572	2.139e-18	87.0	COG1208@1|root,COG1208@2|Bacteria,2GHN7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HKD2_k127_5579427_2	123214.PERMA_1993	1.68e-05	47.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
HKD2_k127_5579427_0	667014.Thein_1158	3e-29	127.0	COG3206@1|root,COG3206@2|Bacteria,2GI4D@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
HKD2_k127_5639956_0	1117379.BABA_00515	2.572e-225	702.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus	91061|Bacilli	E	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_5639956_1	1295642.H839_05739	9.153e-39	151.0	2BP3F@1|root,32HU6@2|Bacteria,1TVYH@1239|Firmicutes,4IFN2@91061|Bacilli,1WHMF@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5639956_2	1348908.KI518592_gene1045	2.471e-05	48.0	2DTM6@1|root,33KVU@2|Bacteria,1VKAV@1239|Firmicutes,4HR45@91061|Bacilli	91061|Bacilli	S	Spo0E like sporulation regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoOE-like
HKD2_k127_5654456_2	218284.CCDN010000002_gene2545	8.142e-52	185.0	COG0582@1|root,COG0582@2|Bacteria,1UIWX@1239|Firmicutes,4ISV4@91061|Bacilli,1ZFA3@1386|Bacillus	91061|Bacilli	L	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
HKD2_k127_5654456_0	218284.CCDN010000002_gene2545	8.072e-130	417.0	COG0582@1|root,COG0582@2|Bacteria,1UIWX@1239|Firmicutes,4ISV4@91061|Bacilli,1ZFA3@1386|Bacillus	91061|Bacilli	L	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
HKD2_k127_5654456_1	1123288.SOV_3c03090	4.663e-123	404.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes	1239|Firmicutes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
HKD2_k127_5654456_3	1461580.CCAS010000025_gene2539	4.451e-11	64.0	COG1943@1|root,COG1943@2|Bacteria,1V553@1239|Firmicutes,4HV8F@91061|Bacilli,1ZCR8@1386|Bacillus	91061|Bacilli	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD2_k127_5668_0	1403313.AXBR01000027_gene5312	0.0	1076.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
HKD2_k127_5668_2	1196029.ALIM01000004_gene4270	7.166e-193	603.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,4HEYD@91061|Bacilli,1ZQZ3@1386|Bacillus	91061|Bacilli	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD2_k127_5668_3	1007103.AFHW01000047_gene2841	1.272e-176	564.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,26RKB@186822|Paenibacillaceae	91061|Bacilli	C	Dihydrolipoyl dehydrogenase	acoL	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
HKD2_k127_5668_1	1403313.AXBR01000027_gene5313	6.257e-309	950.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yfmM	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD2_k127_5668_5	1211035.CD30_06440	7.852e-09	57.0	COG2972@1|root,COG2972@2|Bacteria,1VWNX@1239|Firmicutes,4HXJQ@91061|Bacilli	91061|Bacilli	T	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
HKD2_k127_569434_5	1340434.AXVA01000010_gene5484	1.301e-06	50.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_569434_3	545693.BMQ_5026	7.299e-60	212.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HN1F@91061|Bacilli,1ZHT2@1386|Bacillus	91061|Bacilli	I	Acid phosphatase homologues	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_569434_0	796606.BMMGA3_02470	4.663e-309	952.0	28H8D@1|root,2Z7KA@2|Bacteria,1UB21@1239|Firmicutes,4HA47@91061|Bacilli,1ZB3G@1386|Bacillus	91061|Bacilli	-	-	ykoS	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_569434_1	796606.BMMGA3_02475	1.09e-174	552.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,1ZD2D@1386|Bacillus	91061|Bacilli	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	ykoT	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_569434_4	796606.BMMGA3_02480	1.868e-52	188.0	COG2246@1|root,COG2246@2|Bacteria,1VCW2@1239|Firmicutes,4HKSR@91061|Bacilli,1ZIBW@1386|Bacillus	91061|Bacilli	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HKD2_k127_569434_2	1347086.CCBA010000022_gene2972	6.343e-169	535.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,1ZB5V@1386|Bacillus	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD2_k127_570007_0	1132442.KB889752_gene1929	2.34e-263	814.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,4H9SN@91061|Bacilli,1ZBFV@1386|Bacillus	91061|Bacilli	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
HKD2_k127_570007_10	1121091.AUMP01000016_gene1152	3.862e-65	229.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4HIRG@91061|Bacilli	91061|Bacilli	H	Siroheme synthase	sirC	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
HKD2_k127_570007_5	1132442.KB889752_gene1928	6.017e-139	444.0	COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,1ZBV1@1386|Bacillus	91061|Bacilli	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
HKD2_k127_570007_9	1227360.C176_06387	1.143e-92	306.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,4HFWA@91061|Bacilli,26EV0@186818|Planococcaceae	91061|Bacilli	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
HKD2_k127_570007_1	1145276.T479_13840	9.577e-250	779.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,4HAQW@91061|Bacilli,3IW0X@400634|Lysinibacillus	91061|Bacilli	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
HKD2_k127_570007_6	1403313.AXBR01000027_gene5306	5.28e-127	414.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus	91061|Bacilli	P	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HKD2_k127_570007_3	1403313.AXBR01000027_gene5305	2.399e-156	499.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli,1ZD7V@1386|Bacillus	91061|Bacilli	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	iYO844.BSU33170	FecCD
HKD2_k127_570007_2	1403313.AXBR01000027_gene5304	1.122e-237	743.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,1ZASR@1386|Bacillus	91061|Bacilli	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	yvrA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,CbiZ
HKD2_k127_570007_8	1307436.PBF_18804	5.194e-116	382.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,4HA48@91061|Bacilli,1ZCDR@1386|Bacillus	91061|Bacilli	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
HKD2_k127_570007_4	1403313.AXBR01000027_gene5302	1.63e-154	495.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,4HD85@91061|Bacilli,1ZC9F@1386|Bacillus	91061|Bacilli	E	COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase	cobD	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HKD2_k127_570007_12	1347369.CCAD010000091_gene2159	5.434e-32	133.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,4HJ3G@91061|Bacilli,1ZEBM@1386|Bacillus	91061|Bacilli	H	COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
HKD2_k127_570007_7	1403313.AXBR01000027_gene5300	1.377e-120	392.0	COG0368@1|root,COG0368@2|Bacteria,1V0Q6@1239|Firmicutes,4HEUS@91061|Bacilli,1ZBU1@1386|Bacillus	91061|Bacilli	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
HKD2_k127_570007_11	1174504.AJTN02000251_gene2998	1.446e-48	183.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,4HHCH@91061|Bacilli,1ZDMD@1386|Bacillus	91061|Bacilli	G	Histidine phosphatase superfamily (branch 1)	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HKD2_k127_570007_13	1403313.AXBR01000027_gene5298	6.347e-12	68.0	COG2087@1|root,COG2087@2|Bacteria,1VH9Y@1239|Firmicutes,4HNQX@91061|Bacilli,1ZJB9@1386|Bacillus	91061|Bacilli	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CobU
HKD2_k127_5703002_0	1403313.AXBR01000023_gene2664	0.0	1080.0	COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus	91061|Bacilli	T	Ser protein kinase	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
HKD2_k127_5703002_1	1403313.AXBR01000023_gene2661	1.405e-229	713.0	COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,4HBIH@91061|Bacilli,1ZATH@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0229 family	yhbH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
HKD2_k127_5703002_4	1209989.TepiRe1_0144	9.934e-85	292.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia,42JBK@68295|Thermoanaerobacterales	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
HKD2_k127_5703002_5	1236976.JCM16418_2609	1.085e-55	211.0	COG2199@1|root,COG2199@2|Bacteria,1TR65@1239|Firmicutes,4HBA6@91061|Bacilli,26RG7@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
HKD2_k127_5703002_3	1033734.CAET01000065_gene2197	2.707e-91	310.0	COG2199@1|root,COG2199@2|Bacteria,1UI4C@1239|Firmicutes,4HCZC@91061|Bacilli,1ZGW3@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
HKD2_k127_5703002_2	1403313.AXBR01000023_gene2642	9.321e-125	409.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HB6E@91061|Bacilli,1ZQNX@1386|Bacillus	91061|Bacilli	S	Na -dependent transporter	ybaS	-	-	-	-	-	-	-	-	-	-	-	SBF,SBF_like
HKD2_k127_5703002_6	1403313.AXBR01000023_gene2638	2.635e-15	77.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,4HAE0@91061|Bacilli,1ZD0Q@1386|Bacillus	91061|Bacilli	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
HKD2_k127_5711034_17	796606.BMMGA3_16500	3.448e-95	318.0	COG1277@1|root,COG1277@2|Bacteria,1TRD6@1239|Firmicutes,4HGGV@91061|Bacilli,1ZC8J@1386|Bacillus	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD2_k127_5711034_13	666686.B1NLA3E_02830	1.69e-151	484.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,1ZCRG@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD2_k127_5711034_0	935836.JAEL01000137_gene5423	0.0	1810.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.1.3.6,3.1.4.16	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos,SLH
HKD2_k127_5711034_27	666686.B1NLA3E_01790	1.626e-18	85.0	COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus	91061|Bacilli	N	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	Cu_amine_oxidN1,DUF839
HKD2_k127_5711034_31	666686.B1NLA3E_01790	1.629e-05	48.0	COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus	91061|Bacilli	N	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	Cu_amine_oxidN1,DUF839
HKD2_k127_5711034_20	1423321.AS29_18525	1.606e-71	249.0	COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus	91061|Bacilli	P	COG0672 High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
HKD2_k127_5711034_10	1174504.AJTN02000250_gene2947	1.942e-193	610.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	tetA_3	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
HKD2_k127_5711034_19	1117379.BABA_12156	1.279e-77	263.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,1ZFQ0@1386|Bacillus	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	adaB	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567,ko:K10778,ko:K13531	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HKD2_k127_5711034_30	931626.Awo_c27300	1.476e-05	48.0	COG1277@1|root,COG1277@2|Bacteria,1TQM9@1239|Firmicutes,249MZ@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD2_k127_5711034_24	931626.Awo_c27310	9.996e-30	121.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,25VR0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
HKD2_k127_5711034_28	694427.Palpr_2535	4.436e-06	49.0	COG0500@1|root,COG2226@2|Bacteria,4NYW3@976|Bacteroidetes,2FW0Q@200643|Bacteroidia,2316T@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Domain of unknown function (DUF4062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062
HKD2_k127_5711034_7	1403313.AXBR01000002_gene4466	1.815e-239	746.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmCD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD2_k127_5711034_26	1174504.AJTN02000027_gene1659	3.544e-25	106.0	2BX8I@1|root,2ZNT4@2|Bacteria,1W553@1239|Firmicutes,4I0K7@91061|Bacilli,1ZKUJ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5711034_22	1403313.AXBR01000002_gene4468	5.504e-52	189.0	COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HJ11@91061|Bacilli,1ZQZM@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD2_k127_5711034_12	1403313.AXBR01000002_gene4469	2.958e-166	526.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,1ZBPD@1386|Bacillus	91061|Bacilli	I	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
HKD2_k127_5711034_6	665959.HMPREF1013_05059	3.212e-262	812.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,1ZB3K@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HKD2_k127_5711034_4	1403313.AXBR01000002_gene4475	5.047e-293	902.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,1ZAT1@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HKD2_k127_5711034_23	1403313.AXBR01000002_gene4476	1.542e-44	163.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1ZH54@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HKD2_k127_5711034_9	1403313.AXBR01000002_gene4477	2.805e-204	640.0	COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,1ZBGV@1386|Bacillus	91061|Bacilli	S	COG4851 Protein involved in sex pheromone biosynthesis	camS	-	-	-	-	-	-	-	-	-	-	-	CamS
HKD2_k127_5711034_2	1403313.AXBR01000002_gene4478	0.0	1100.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZATN@1386|Bacillus	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HKD2_k127_5711034_1	1403313.AXBR01000002_gene4479	0.0	1285.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD2_k127_5711034_16	1403313.AXBR01000002_gene4480	5.775e-121	391.0	COG1646@1|root,COG1646@2|Bacteria,1TQQK@1239|Firmicutes,4H9YW@91061|Bacilli,1ZBBT@1386|Bacillus	91061|Bacilli	I	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales	pcrB	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
HKD2_k127_5711034_21	1403313.AXBR01000002_gene4481	1.71e-52	186.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,4HKS8@91061|Bacilli,1ZH87@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yerC	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
HKD2_k127_5711034_14	1403313.AXBR01000002_gene4482	2.756e-131	427.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
HKD2_k127_5711034_3	1403313.AXBR01000002_gene4483	2.189e-314	969.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,1ZAY2@1386|Bacillus	91061|Bacilli	F	adenine deaminase	yerA	GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD2_k127_5711034_25	1174504.AJTN02000208_gene3378	2.278e-25	108.0	2EAXM@1|root,334YP@2|Bacteria,1VIHS@1239|Firmicutes,4HR0C@91061|Bacilli,1ZJ0E@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HKD2_k127_5711034_8	1403313.AXBR01000002_gene4485	2.04e-218	683.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,1ZCE3@1386|Bacillus	91061|Bacilli	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
HKD2_k127_5711034_5	1403313.AXBR01000002_gene4486	2.597e-292	901.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,1ZD5E@1386|Bacillus	91061|Bacilli	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HKD2_k127_5711034_18	1403313.AXBR01000002_gene4487	4.524e-85	285.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,1ZFSE@1386|Bacillus	91061|Bacilli	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
HKD2_k127_5711034_11	1403313.AXBR01000002_gene4488	1.626e-183	579.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,1ZBPS@1386|Bacillus	91061|Bacilli	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD2_k127_5711034_29	1385514.N782_03495	6.373e-06	49.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5711034_15	1403313.AXBR01000002_gene4489	9.036e-125	401.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,1ZCE0@1386|Bacillus	91061|Bacilli	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
HKD2_k127_5764299_1	1403313.AXBR01000007_gene382	2.243e-158	504.0	COG0492@1|root,COG0492@2|Bacteria,1TQGS@1239|Firmicutes,4HBIS@91061|Bacilli,1ZCBR@1386|Bacillus	91061|Bacilli	O	COG0492 Thioredoxin reductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
HKD2_k127_5764299_3	1403313.AXBR01000007_gene380	1.295e-100	333.0	COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,4HCGD@91061|Bacilli,1ZBUQ@1386|Bacillus	91061|Bacilli	S	Involved in the degradation of specific anti-sigma factors	prsW	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
HKD2_k127_5764299_2	1403313.AXBR01000007_gene379	8.709e-143	457.0	COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4HA2V@91061|Bacilli,1ZB40@1386|Bacillus	91061|Bacilli	M	Spore cortex-lytic enzyme	sleB	GO:0005575,GO:0005623,GO:0042763,GO:0044464	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,PG_binding_1
HKD2_k127_5764299_0	1403313.AXBR01000007_gene378	1.468e-212	667.0	COG2959@1|root,COG2959@2|Bacteria,1TT9K@1239|Firmicutes,4HBM9@91061|Bacilli,1ZB4M@1386|Bacillus	91061|Bacilli	H	sporulation protein	ypeB	-	-	ko:K06313	-	-	-	-	ko00000	-	-	-	PepSY,YPEB
HKD2_k127_5764299_5	1174504.AJTN02000187_gene4733	4.876e-71	247.0	COG5581@1|root,COG5581@2|Bacteria,1V31U@1239|Firmicutes,4HGFE@91061|Bacilli,1ZCCG@1386|Bacillus	91061|Bacilli	M	Flagellar protein YcgR	ypfA	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
HKD2_k127_5764299_4	1403313.AXBR01000007_gene375	1.709e-94	313.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HKD2_k127_5770871_0	471223.GWCH70_2289	3.051e-127	409.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1WG7Q@129337|Geobacillus	91061|Bacilli	E	ATPases associated with a variety of cellular activities	artM	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HKD2_k127_5770871_2	91604.ID47_03315	1.073e-61	219.0	COG0765@1|root,COG0765@2|Bacteria,1N786@1224|Proteobacteria,2TRW3@28211|Alphaproteobacteria,47GQG@766|Rickettsiales	766|Rickettsiales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HKD2_k127_5770871_1	1169144.KB910924_gene701	3.164e-70	241.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli,1ZQ0V@1386|Bacillus	91061|Bacilli	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD2_k127_5779400_7	1403313.AXBR01000021_gene3178	5.491e-44	160.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,1ZFN0@1386|Bacillus	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HKD2_k127_5779400_0	1403313.AXBR01000021_gene3179	4.592e-237	743.0	COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus	91061|Bacilli	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HKD2_k127_5779400_8	1403313.AXBR01000021_gene3180	3.766e-36	142.0	2DSU9@1|root,33HF9@2|Bacteria,1VIQ9@1239|Firmicutes,4HPSB@91061|Bacilli,1ZG8K@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3397
HKD2_k127_5779400_2	1403313.AXBR01000021_gene3181	1.301e-106	353.0	COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZQAB@1386|Bacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15110	ApbA,ApbA_C
HKD2_k127_5779400_5	1403313.AXBR01000021_gene3182	1.072e-72	247.0	COG0454@1|root,COG0454@2|Bacteria,1V259@1239|Firmicutes,4HFSD@91061|Bacilli,1ZFN4@1386|Bacillus	91061|Bacilli	K	n-acetyltransferase	ylbP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
HKD2_k127_5779400_6	1403313.AXBR01000021_gene3183	5.468e-62	219.0	2C8MW@1|root,305IT@2|Bacteria,1V5HI@1239|Firmicutes,4HGP6@91061|Bacilli,1ZBX1@1386|Bacillus	91061|Bacilli	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	ylbO	-	-	ko:K06314	-	-	-	-	ko00000,ko03000	-	-	-	Myb_DNA-bind_6
HKD2_k127_5779400_3	1403313.AXBR01000021_gene3184	3.688e-97	323.0	COG1024@1|root,COG1024@2|Bacteria,1UZHP@1239|Firmicutes,4HEEK@91061|Bacilli,1ZB0V@1386|Bacillus	91061|Bacilli	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD2_k127_5779400_9	665959.HMPREF1013_00444	1.369e-30	123.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,1ZJ4F@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HKD2_k127_5779400_4	1403313.AXBR01000021_gene3185	7.063e-89	295.0	COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,1ZGJH@1386|Bacillus	91061|Bacilli	S	metal-binding, possibly nucleic acid-binding protein	ylbN	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HKD2_k127_5779400_1	1403313.AXBR01000021_gene3186	1.441e-131	427.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,1ZC63@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0348 family	ylbM	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
HKD2_k127_5791546_7	886293.Sinac_7345	2.205e-28	130.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
HKD2_k127_5791546_4	269084.syc0200_d	1.096e-61	229.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1GYX2@1129|Synechococcus	1117|Cyanobacteria	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_8,PAS_9,Response_reg
HKD2_k127_5791546_1	634956.Geoth_1943	4.115e-134	439.0	COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	hemAT	-	-	ko:K06595	-	-	-	-	ko00000,ko02035	-	-	-	MCPsignal,Protoglobin
HKD2_k127_5791546_8	1385514.N782_03495	5.401e-05	46.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5791546_0	1117379.BABA_02192	1.773e-183	578.0	COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,4HMYE@91061|Bacilli,1ZM90@1386|Bacillus	91061|Bacilli	S	Belongs to the pirin family	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
HKD2_k127_5791546_3	1117379.BABA_19421	5.569e-108	351.0	COG2249@1|root,COG2249@2|Bacteria,1U3MF@1239|Firmicutes,4HCM7@91061|Bacilli,1ZGKD@1386|Bacillus	91061|Bacilli	S	NAD(P)H dehydrogenase	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
HKD2_k127_5791546_5	1078085.HMPREF1210_01026	1.109e-60	212.0	COG1846@1|root,COG1846@2|Bacteria,1V5I3@1239|Firmicutes,4HIAE@91061|Bacilli,26HED@186818|Planococcaceae	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_5791546_2	1211035.CD30_00650	1.062e-128	417.0	COG1406@1|root,COG1406@2|Bacteria,1V46M@1239|Firmicutes,4HU2P@91061|Bacilli,3IZ2Y@400634|Lysinibacillus	91061|Bacilli	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5791546_6	1034347.CAHJ01000021_gene3381	2.025e-57	201.0	COG4753@1|root,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,4IIUI@91061|Bacilli,1ZJE9@1386|Bacillus	91061|Bacilli	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
HKD2_k127_5791561_1	1340434.AXVA01000003_gene2458	3.13e-134	431.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20951	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	PQQ_2
HKD2_k127_5791561_3	1226994.AMZB01000092_gene783	3.992e-15	76.0	COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,1RP4Z@1236|Gammaproteobacteria,1YERU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Catalyzes the desulfonation of aliphatic sulfonates	ssuD	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005515,GO:0006082,GO:0006790,GO:0006950,GO:0008150,GO:0008152,GO:0008726,GO:0009056,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016712,GO:0019694,GO:0042802,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0046306,GO:0050896,GO:0055114,GO:0071704,GO:1901575	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_2212,iPC815.YPO3625	Bac_luciferase
HKD2_k127_5791561_2	349161.Dred_1346	7.03e-134	457.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
HKD2_k127_5791561_0	666686.B1NLA3E_02795	2.902e-246	766.0	COG1653@1|root,COG1653@2|Bacteria,1V31R@1239|Firmicutes,4HWQY@91061|Bacilli	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
HKD2_k127_5792991_2	1042163.BRLA_c005590	6.014e-74	254.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,26UGV@186822|Paenibacillaceae	91061|Bacilli	M	PFAM membrane bound O-acyl transferase MBOAT family protein	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
HKD2_k127_5792991_0	1340434.AXVA01000012_gene2961	1.495e-206	651.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus	91061|Bacilli	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
HKD2_k127_5792991_1	1131730.BAVI_13994	1.052e-78	269.0	29H6Z@1|root,3044I@2|Bacteria,1V4SZ@1239|Firmicutes,4HHCE@91061|Bacilli,1ZFWE@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5792991_3	1174504.AJTN02000153_gene971	1.553e-35	146.0	2E48W@1|root,32Z4Q@2|Bacteria,1VF41@1239|Firmicutes,4HPBF@91061|Bacilli,1ZGKF@1386|Bacillus	91061|Bacilli	-	-	cotB	-	-	ko:K06325	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_5817171_6	1403313.AXBR01000030_gene5345	6.398e-73	246.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HKD2_k127_5817171_3	796606.BMMGA3_00400	1.84e-151	482.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,1ZBFC@1386|Bacillus	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
HKD2_k127_5817171_2	1403313.AXBR01000030_gene5342	1.903e-167	529.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZBC7@1386|Bacillus	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD2_k127_5817171_4	1403313.AXBR01000030_gene5341	3.347e-130	420.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD2_k127_5817171_7	935836.JAEL01000045_gene3344	1.052e-51	184.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,1ZGZ7@1386|Bacillus	91061|Bacilli	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
HKD2_k127_5817171_5	1403313.AXBR01000030_gene5339	3.145e-76	259.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,1ZGBC@1386|Bacillus	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
HKD2_k127_5817171_8	315749.Bcer98_0070	8.603e-13	70.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	yazB	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HKD2_k127_5817171_1	796606.BMMGA3_00450	5.104e-182	572.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,1ZC6T@1386|Bacillus	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
HKD2_k127_5817171_0	1403313.AXBR01000030_gene5336	1.051e-277	858.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,1ZAVI@1386|Bacillus	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD2_k127_5820901_0	1461580.CCAS010000016_gene1947	1.499e-164	526.0	COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli,1ZBNV@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD2_k127_5820901_2	1117379.BABA_19456	1.115e-139	448.0	COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HG9F@91061|Bacilli,1ZAQN@1386|Bacillus	91061|Bacilli	S	membrane	ycgQ	-	-	ko:K08986	-	-	-	-	ko00000	-	-	-	DUF1980
HKD2_k127_5820901_1	1347369.CCAD010000065_gene3764	3.626e-140	450.0	COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli,1ZC03@1386|Bacillus	91061|Bacilli	S	permeases	ycgR	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
HKD2_k127_5820901_3	1340434.AXVA01000012_gene3036	8.817e-17	81.0	COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZCD2@1386|Bacillus	91061|Bacilli	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
HKD2_k127_5821557_0	574375.BAGA_10650	5.457e-150	482.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	yhfS	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_5821557_5	1196029.ALIM01000014_gene3525	9.87e-06	48.0	COG0318@1|root,COG0318@2|Bacteria,1TT9C@1239|Firmicutes,4HBQ2@91061|Bacilli,1ZCW8@1386|Bacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	vraA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5821557_2	1340434.AXVA01000012_gene2935	8.178e-116	387.0	COG0318@1|root,COG0318@2|Bacteria,1TT9C@1239|Firmicutes,4HBQ2@91061|Bacilli,1ZCW8@1386|Bacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	vraA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD2_k127_5821557_3	315730.BcerKBAB4_3315	1.249e-55	200.0	COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,1ZC7W@1386|Bacillus	91061|Bacilli	S	BioY family	bioY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HKD2_k127_5821557_1	1231057.AMGD01000067_gene1188	1.408e-130	423.0	COG0679@1|root,COG0679@2|Bacteria,1TXY4@1239|Firmicutes,4HBB5@91061|Bacilli,26DI5@186818|Planococcaceae	91061|Bacilli	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HKD2_k127_5821557_4	1403313.AXBR01000028_gene5062	1.727e-43	160.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,1ZB39@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes	dbpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD2_k127_5824439_12	1347369.CCAD010000078_gene3016	1.086e-18	88.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HDYW@91061|Bacilli,1ZC45@1386|Bacillus	91061|Bacilli	M	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	ykoN	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD2_k127_5824439_2	1211814.CAPG01000036_gene1943	1.108e-121	395.0	COG3541@1|root,COG3541@2|Bacteria,1TT57@1239|Firmicutes,4HD38@91061|Bacilli,1ZBMK@1386|Bacillus	91061|Bacilli	S	Predicted nucleotidyltransferase	ycgL	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
HKD2_k127_5824439_1	1243664.CAVL020000015_gene1919	5.564e-123	401.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HA1X@91061|Bacilli,1ZCDN@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_5824439_5	1356854.N007_13375	3.595e-57	215.0	COG0477@1|root,COG2814@2|Bacteria,1V61H@1239|Firmicutes,4HU8X@91061|Bacilli	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_5824439_3	1243664.CAVL020000032_gene2845	1.568e-109	360.0	COG0840@1|root,COG0840@2|Bacteria,1TQNQ@1239|Firmicutes,4HD0J@91061|Bacilli,1ZDDE@1386|Bacillus	91061|Bacilli	NT	PAS fold	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_9
HKD2_k127_5824439_9	1294265.JCM21738_5497	2.726e-40	154.0	COG4087@1|root,COG4087@2|Bacteria,1VA72@1239|Firmicutes,4IIJM@91061|Bacilli,1ZNNZ@1386|Bacillus	91061|Bacilli	S	Soluble P-type ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5824439_13	1131730.BAVI_09276	8.801e-10	60.0	29RGZ@1|root,30CJV@2|Bacteria,1UA0K@1239|Firmicutes,4IK96@91061|Bacilli,1ZFZZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5824439_7	1131730.BAVI_09276	1.056e-50	182.0	29RGZ@1|root,30CJV@2|Bacteria,1UA0K@1239|Firmicutes,4IK96@91061|Bacilli,1ZFZZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5824439_4	666686.B1NLA3E_08285	1.627e-87	294.0	COG2323@1|root,COG2323@2|Bacteria,1TX6U@1239|Firmicutes,4HEB2@91061|Bacilli,1ZQ03@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD2_k127_5824439_0	545693.BMQ_1603	4.051e-148	473.0	COG2267@1|root,COG2267@2|Bacteria,1V9HD@1239|Firmicutes,4HU8B@91061|Bacilli,1ZGAB@1386|Bacillus	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HKD2_k127_5824439_6	1403313.AXBR01000007_gene175	5.082e-56	197.0	COG1387@1|root,COG1387@2|Bacteria,1TT9D@1239|Firmicutes,4HE92@91061|Bacilli,1ZQG0@1386|Bacillus	91061|Bacilli	E	PHP domain	hisJ3	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HKD2_k127_5839915_10	1174504.AJTN02000203_gene2776	2.269e-48	174.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
HKD2_k127_5839915_9	1403313.AXBR01000030_gene5372	1.087e-55	195.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,4HIPT@91061|Bacilli,1ZGXK@1386|Bacillus	91061|Bacilli	D	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation	spoVG	GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
HKD2_k127_5839915_8	1034347.CAHJ01000087_gene1730	4.385e-67	229.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,1ZG9Q@1386|Bacillus	91061|Bacilli	J	translation initiation inhibitor, yjgF family	yabJ	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046360,GO:0046361,GO:0046394,GO:0046459,GO:0051790,GO:0071704,GO:0072330,GO:1901576	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HKD2_k127_5839915_5	1403313.AXBR01000030_gene5374	7.734e-146	465.0	COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,1ZAW9@1386|Bacillus	91061|Bacilli	F	pur operon repressor	purR	-	-	ko:K09685	-	-	-	-	ko00000,ko03000	-	-	-	Pribosyltran,PuR_N
HKD2_k127_5839915_1	1403313.AXBR01000030_gene5375	5.137e-164	518.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,1ZAYT@1386|Bacillus	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
HKD2_k127_5839915_12	1174504.AJTN02000203_gene2781	2.731e-24	102.0	2E2ZT@1|root,32Y0E@2|Bacteria,1VEHE@1239|Firmicutes,4HNK8@91061|Bacilli,1ZITS@1386|Bacillus	91061|Bacilli	S	DNA topological change	sspF	-	-	ko:K06423	-	-	-	-	ko00000	-	-	-	SASP
HKD2_k127_5839915_11	1403313.AXBR01000030_gene5377	3.895e-42	155.0	COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,1ZI19@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	veg	-	-	-	-	-	-	-	-	-	-	-	VEG
HKD2_k127_5839915_2	1403313.AXBR01000030_gene5378	1.684e-156	498.0	28HCB@1|root,2Z7P7@2|Bacteria,1TNZK@1239|Firmicutes,4HBET@91061|Bacilli,1ZCTC@1386|Bacillus	91061|Bacilli	S	peptidase	yabG	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0043591,GO:0043593,GO:0044426,GO:0044462,GO:0044464,GO:0071944	-	ko:K06436	-	-	-	-	ko00000	-	-	-	Peptidase_U57
HKD2_k127_5839915_3	1403313.AXBR01000030_gene5379	2.211e-151	483.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1ZBZX@1386|Bacillus	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HKD2_k127_5839915_7	1307436.PBF_22592	3.124e-76	260.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,1ZFNN@1386|Bacillus	91061|Bacilli	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
HKD2_k127_5839915_13	1385514.N782_03495	3.318e-06	52.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5839915_4	1403313.AXBR01000030_gene5381	1.603e-148	480.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus	91061|Bacilli	T	protein conserved in bacteria	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
HKD2_k127_5839915_6	1403313.AXBR01000030_gene5382	5.161e-141	451.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus	91061|Bacilli	L	hydrolase, TatD	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HKD2_k127_5839915_0	1403313.AXBR01000030_gene5383	0.0	1153.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD2_k127_5839915_14	1340434.AXVA01000010_gene5484	1.929e-05	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5875037_2	1403313.AXBR01000009_gene905	3.657e-79	269.0	COG2186@1|root,COG2186@2|Bacteria,1V3Z4@1239|Firmicutes,4HI3J@91061|Bacilli,1ZDS7@1386|Bacillus	91061|Bacilli	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
HKD2_k127_5875037_1	1403313.AXBR01000009_gene906	1.628e-234	729.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZBAH@1386|Bacillus	91061|Bacilli	C	Malate dehydrogenase	ytsJ	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
HKD2_k127_5875037_0	796606.BMMGA3_13110	0.0	1307.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HKD2_k127_5875037_6	1340434.AXVA01000010_gene5484	1.899e-08	57.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5875037_5	1403313.AXBR01000009_gene909	3.789e-57	199.0	2CBNY@1|root,330BE@2|Bacteria,1VGPH@1239|Firmicutes,4HNX7@91061|Bacilli,1ZH6P@1386|Bacillus	91061|Bacilli	S	Sporulation protein YtrH	ytrH	-	-	-	-	-	-	-	-	-	-	-	Spore_YtrH
HKD2_k127_5875037_3	1403313.AXBR01000009_gene910	4.466e-68	236.0	2AV7G@1|root,31KY3@2|Bacteria,1V73K@1239|Firmicutes,4HJ3F@91061|Bacilli,1ZHIX@1386|Bacillus	91061|Bacilli	-	-	ytrI	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5875037_4	1294265.JCM21738_2389	7.713e-67	231.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HBDU@91061|Bacilli,1ZBUJ@1386|Bacillus	91061|Bacilli	M	Mechanosensitive ion channel	yhdY	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HKD2_k127_5892791_6	1340434.AXVA01000016_gene701	6.516e-07	51.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5892791_4	1403313.AXBR01000006_gene76	2.365e-108	355.0	2ESB9@1|root,33JW0@2|Bacteria,1VMVV@1239|Firmicutes,4HSTZ@91061|Bacilli,1ZD8X@1386|Bacillus	91061|Bacilli	-	-	yodN	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5892791_5	1347369.CCAD010000048_gene231	8.162e-23	99.0	28VRR@1|root,2ZHTJ@2|Bacteria,1W6RM@1239|Firmicutes,4IFAF@91061|Bacilli,1ZITN@1386|Bacillus	91061|Bacilli	S	YozD-like protein	yozD	-	-	-	-	-	-	-	-	-	-	-	YozD
HKD2_k127_5892791_3	1403313.AXBR01000006_gene74	6.63e-129	414.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,1ZCBV@1386|Bacillus	91061|Bacilli	F	Purine nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD2_k127_5892791_0	1403313.AXBR01000006_gene73	2.56e-230	722.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
HKD2_k127_5892791_2	1403313.AXBR01000006_gene69	1.092e-132	426.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1ZB5Z@1386|Bacillus	91061|Bacilli	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	mtnU	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HKD2_k127_5892791_1	1403313.AXBR01000006_gene68	2.966e-185	585.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus	91061|Bacilli	E	Aminotransferase	mtnE	-	-	ko:K08969	ko00270,ko01100,map00270,map01100	M00034	R07396	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_5892821_4	1243664.CAVL020000037_gene1072	2.476e-37	143.0	COG1414@1|root,COG1414@2|Bacteria,1V7RC@1239|Firmicutes,4HITR@91061|Bacilli,1ZER9@1386|Bacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_5892821_1	1132442.KB889752_gene3700	4.667e-176	562.0	COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HDUQ@91061|Bacilli,1ZC8H@1386|Bacillus	91061|Bacilli	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	ko:K05548	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4,Sugar_tr
HKD2_k127_5892821_7	279010.BL01432	2.64e-25	106.0	COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,1ZJ7C@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0346 family	yozE	-	-	-	-	-	-	-	-	-	-	-	YozE_SAM_like
HKD2_k127_5892821_10	1196029.ALIM01000049_gene4723	1.495e-07	60.0	COG4632@1|root,COG4632@2|Bacteria,1UP29@1239|Firmicutes,4IQIR@91061|Bacilli	1239|Firmicutes	G	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
HKD2_k127_5892821_0	796606.BMMGA3_09335	7.89e-233	725.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,1ZDR1@1386|Bacillus	91061|Bacilli	P	COG0475 Kef-type K transport systems, membrane components	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD2_k127_5892821_6	796606.BMMGA3_09330	2.064e-25	109.0	2EJIK@1|root,33D9H@2|Bacteria,1VKCQ@1239|Firmicutes,4HR92@91061|Bacilli,1ZIHV@1386|Bacillus	91061|Bacilli	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
HKD2_k127_5892821_3	796606.BMMGA3_09325	1.158e-43	163.0	2FE6R@1|root,3466J@2|Bacteria,1W073@1239|Firmicutes,4HY9B@91061|Bacilli,1ZI7Z@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5892821_9	1118054.CAGW01000003_gene64	9.805e-21	97.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,4HNI0@91061|Bacilli,26ZZT@186822|Paenibacillaceae	91061|Bacilli	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD2_k127_5892821_8	138119.DSY2098	1.036e-22	101.0	COG0239@1|root,COG0239@2|Bacteria,1UDKA@1239|Firmicutes,25IC6@186801|Clostridia,266J3@186807|Peptococcaceae	186801|Clostridia	D	CrcB-like protein, Camphor Resistance (CrcB)	-	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD2_k127_5892821_2	935837.JAEK01000005_gene4411	2.682e-119	388.0	COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZB5B@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	ymfD	-	-	ko:K08221	-	-	-	-	ko00000,ko02000	2.A.1.32	-	-	MFS_1,MFS_2,Sugar_tr
HKD2_k127_5902509_2	1403313.AXBR01000010_gene974	3.463e-146	467.0	COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,1ZAYX@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_5902509_6	935837.JAEK01000015_gene5042	5.437e-22	96.0	2EH45@1|root,33AW4@2|Bacteria,1VF2V@1239|Firmicutes,4HP8P@91061|Bacilli,1ZJAU@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5902509_5	1403313.AXBR01000010_gene973	3.864e-40	151.0	COG5584@1|root,COG5584@2|Bacteria,1VEIQ@1239|Firmicutes,4HNS2@91061|Bacilli,1ZJ31@1386|Bacillus	91061|Bacilli	S	small secreted protein	ytzB	-	-	-	-	-	-	-	-	-	-	-	PepSY
HKD2_k127_5902509_0	1403313.AXBR01000010_gene972	9.364e-216	672.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZAXE@1386|Bacillus	91061|Bacilli	G	COG1363 Cellulase M and related proteins	pepA	-	3.4.11.7	ko:K01261,ko:K01269	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M42
HKD2_k127_5902509_9	1211814.CAPG01000078_gene3708	5.724e-05	46.0	COG1986@1|root,COG1986@2|Bacteria,1V6CG@1239|Firmicutes,4HIVY@91061|Bacilli,1ZGKX@1386|Bacillus	91061|Bacilli	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	yjjX	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
HKD2_k127_5902509_4	1403313.AXBR01000010_gene967	4.367e-54	191.0	COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,1ZHAS@1386|Bacillus	91061|Bacilli	CO	Thioredoxin	ytpP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD2_k127_5902509_3	1403313.AXBR01000010_gene966	4.403e-138	442.0	COG4848@1|root,COG4848@2|Bacteria,1TTBU@1239|Firmicutes,4HAD1@91061|Bacilli,1ZBQ7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0354 family	ytpQ	-	-	-	-	-	-	-	-	-	-	-	DUF1444
HKD2_k127_5902509_1	1403313.AXBR01000010_gene964	1.744e-189	612.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	sftA	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Ftsk_gamma
HKD2_k127_5915909_8	1033734.CAET01000058_gene1906	1.456e-06	54.0	29R6C@1|root,30C7Q@2|Bacteria,1U9C7@1239|Firmicutes,4IJF4@91061|Bacilli,1ZK3G@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5915909_5	1145276.T479_13425	8.005e-33	135.0	2E69W@1|root,330XT@2|Bacteria,1VFAJ@1239|Firmicutes,4HQVI@91061|Bacilli,3IZKG@400634|Lysinibacillus	91061|Bacilli	S	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
HKD2_k127_5915909_10	1340434.AXVA01000010_gene5484	0.0004293	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5915909_2	1403313.AXBR01000017_gene3740	4.578e-86	289.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_5915909_4	1227360.C176_11289	5.636e-36	136.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,26FTN@186818|Planococcaceae	91061|Bacilli	K	'Cold-shock' DNA-binding domain	cspL	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_5915909_6	666686.B1NLA3E_21985	5.392e-28	113.0	2EVH2@1|root,33NXG@2|Bacteria,1VP4G@1239|Firmicutes,4HS60@91061|Bacilli,1ZJM0@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5915909_3	1461580.CCAS010000046_gene3448	2.864e-70	240.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,1ZG7S@1386|Bacillus	91061|Bacilli	J	RNA binding protein (contains ribosomal protein S1 domain)	yabR	-	-	ko:K07571	-	-	-	-	ko00000	-	-	-	S1
HKD2_k127_5915909_0	666686.B1NLA3E_11490	4.347e-124	401.0	COG0500@1|root,COG2226@2|Bacteria,1V261@1239|Firmicutes,4HI81@91061|Bacilli,1ZAPH@1386|Bacillus	91061|Bacilli	Q	O-methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
HKD2_k127_5915909_1	1117379.BABA_03579	3.646e-106	346.0	COG1028@1|root,COG1028@2|Bacteria,1U9MA@1239|Firmicutes,4IPMW@91061|Bacilli,1ZRDA@1386|Bacillus	91061|Bacilli	IQ	Short-chain dehydrogenase reductase sdr	ycdF	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
HKD2_k127_5931844_5	1340434.AXVA01000010_gene5484	2.715e-09	58.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5931844_0	1132442.KB889752_gene1755	5.253e-224	698.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus	91061|Bacilli	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	yhaA1	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD2_k127_5931844_1	1408303.JNJJ01000057_gene1328	4.276e-203	640.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_5931844_3	1408303.JNJJ01000057_gene1327	1.352e-113	369.0	COG0745@1|root,COG0745@2|Bacteria,1TS8Z@1239|Firmicutes,4HC86@91061|Bacilli,1ZB3W@1386|Bacillus	91061|Bacilli	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_5931844_4	935836.JAEL01000025_gene2361	3.129e-55	199.0	COG0398@1|root,COG0398@2|Bacteria,1V19V@1239|Firmicutes,4HEIJ@91061|Bacilli,1ZGYT@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	yqeD	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD2_k127_5931844_2	997296.PB1_12434	4.116e-116	378.0	COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,1ZBEQ@1386|Bacillus	91061|Bacilli	Q	Multi-copper	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD2_k127_5932539_7	1403313.AXBR01000008_gene623	9.123e-104	347.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HKD2_k127_5932539_9	1403313.AXBR01000008_gene624	1.558e-98	323.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,1ZBGM@1386|Bacillus	91061|Bacilli	F	COG2131 Deoxycytidylate deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HKD2_k127_5932539_16	1174504.AJTN02000155_gene2008	1.787e-54	199.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,1ZH4N@1386|Bacillus	91061|Bacilli	L	COG1555 DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HKD2_k127_5932539_6	1403313.AXBR01000008_gene626	3.418e-117	383.0	COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZBFA@1386|Bacillus	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	comER	-	-	ko:K02239	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	F420_oxidored,P5CR_dimer
HKD2_k127_5932539_4	1403313.AXBR01000008_gene627	1.706e-126	407.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,1ZB0Y@1386|Bacillus	91061|Bacilli	Q	Methyltransferase	yqeM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD2_k127_5932539_14	1403313.AXBR01000008_gene628	6.828e-62	214.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,1ZGYR@1386|Bacillus	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HKD2_k127_5932539_13	1382315.JPOI01000001_gene1767	1.366e-72	249.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1WFI5@129337|Geobacillus	91061|Bacilli	H	Metal dependent phosphohydrolases with conserved 'HD' motif.	yqeK	-	-	-	-	-	-	-	-	-	-	-	HD
HKD2_k127_5932539_10	1403313.AXBR01000008_gene630	1.185e-93	311.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD2_k127_5932539_17	1403313.AXBR01000008_gene631	9.082e-51	181.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,1ZH83@1386|Bacillus	91061|Bacilli	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
HKD2_k127_5932539_5	1403313.AXBR01000008_gene632	7.006e-121	393.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,1ZANW@1386|Bacillus	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HKD2_k127_5932539_0	1403313.AXBR01000008_gene633	8.186e-221	687.0	COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,1ZBES@1386|Bacillus	91061|Bacilli	S	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis	yqeH	GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113	-	ko:K06948	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HKD2_k127_5932539_15	1460635.JCM19038_96	2.008e-55	199.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli	91061|Bacilli	S	hydrolase of the HAD superfamily	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
HKD2_k127_5932539_19	1196031.ALEG01000061_gene2142	4.21e-13	70.0	2EIH6@1|root,33C8I@2|Bacteria,1VMKK@1239|Firmicutes,4HRH7@91061|Bacilli,1ZJY1@1386|Bacillus	91061|Bacilli	S	Sporulation inhibitor A	sda	-	-	ko:K06371	-	-	-	-	ko00000	-	-	-	Sda
HKD2_k127_5932539_8	1403313.AXBR01000008_gene635	3.854e-103	341.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,1ZAZ4@1386|Bacillus	91061|Bacilli	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HKD2_k127_5932539_11	1403313.AXBR01000008_gene636	3.042e-89	296.0	COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HFUP@91061|Bacilli,1ZC3H@1386|Bacillus	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HKD2_k127_5932539_3	1403313.AXBR01000008_gene638	1.846e-136	437.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,4HBY2@91061|Bacilli,1ZB3Q@1386|Bacillus	91061|Bacilli	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD2_k127_5932539_18	796606.BMMGA3_12165	3.972e-14	74.0	29RXR@1|root,30D21@2|Bacteria,1UAQC@1239|Firmicutes,4IM31@91061|Bacilli,1ZIYV@1386|Bacillus	91061|Bacilli	S	YrhC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YrhC
HKD2_k127_5932539_1	1403313.AXBR01000008_gene640	3.69e-216	674.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	mccB	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27250	Cys_Met_Meta_PP
HKD2_k127_5932539_2	1403313.AXBR01000008_gene641	2.903e-157	500.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZD93@1386|Bacillus	91061|Bacilli	E	Cysteine synthase	mccA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.134,2.5.1.47	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00609	R00897,R03601,R04859,R10305	RC00020,RC00069,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02385	PALP
HKD2_k127_5932539_12	1403313.AXBR01000008_gene642	3.731e-85	283.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,1ZB7T@1386|Bacillus	91061|Bacilli	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HKD2_k127_5943614_0	1347369.CCAD010000035_gene1091	2.809e-274	856.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,1ZCEN@1386|Bacillus	91061|Bacilli	O	COG1331 Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
HKD2_k127_5943614_1	1403313.AXBR01000017_gene3613	1.669e-47	171.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZBQI@1386|Bacillus	91061|Bacilli	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD2_k127_5987166_11	1243664.CAVL020000039_gene565	1.424e-11	68.0	COG3418@1|root,COG3418@2|Bacteria,1VF67@1239|Firmicutes,4HMI4@91061|Bacilli,1ZJCA@1386|Bacillus	91061|Bacilli	NOU	FlgN protein	yvyG	-	-	-	-	-	-	-	-	-	-	-	FlgN
HKD2_k127_5987166_0	1403313.AXBR01000026_gene5137	6.827e-210	664.0	COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,1TPXH@1239|Firmicutes,4HAKM@91061|Bacilli,1ZB70@1386|Bacillus	91061|Bacilli	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD2_k127_5987166_4	1403313.AXBR01000026_gene5136	1.001e-120	393.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,4HCCZ@91061|Bacilli,1ZC4T@1386|Bacillus	91061|Bacilli	N	Belongs to the bacterial flagellin family	flgL	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
HKD2_k127_5987166_7	796606.BMMGA3_14990	7.115e-61	214.0	2AZFG@1|root,31RPF@2|Bacteria,1V1GV@1239|Firmicutes,4IRUR@91061|Bacilli,1ZRY9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5987166_8	796606.BMMGA3_14985	6.057e-53	190.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,4HKYD@91061|Bacilli,1ZI2D@1386|Bacillus	91061|Bacilli	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
HKD2_k127_5987166_10	1174504.AJTN02000189_gene725	1.883e-28	117.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,1ZJ2S@1386|Bacillus	91061|Bacilli	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
HKD2_k127_5987166_6	768704.Desmer_3928	4.843e-85	311.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,260YN@186807|Peptococcaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fla	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
HKD2_k127_5987166_9	1450694.BTS2_4005	7.525e-39	152.0	2E8TT@1|root,3334G@2|Bacteria,1VGVK@1239|Firmicutes,4HQS1@91061|Bacilli,1ZIRU@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_5987166_3	1071073.KI530539_gene85	8.927e-152	501.0	COG2604@1|root,COG2604@2|Bacteria,1U2BC@1239|Firmicutes,4HDVB@91061|Bacilli,1ZFBX@1386|Bacillus	91061|Bacilli	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
HKD2_k127_5987166_2	1134413.ANNK01000034_gene1254	4.035e-181	570.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,4IQQV@91061|Bacilli,1ZRMU@1386|Bacillus	91061|Bacilli	M	GDP-mannose 4,6 dehydratase	pseB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
HKD2_k127_5987166_1	198467.NP92_07455	3.854e-199	625.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,21XCM@150247|Anoxybacillus	91061|Bacilli	E	Beta-eliminating lyase	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
HKD2_k127_5987166_5	198467.NP92_07460	2.726e-97	323.0	COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,4IEG0@91061|Bacilli,21X4V@150247|Anoxybacillus	91061|Bacilli	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
HKD2_k127_6039360_2	666686.B1NLA3E_22040	1.76e-123	411.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZS1A@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
HKD2_k127_6039360_4	1340434.AXVA01000004_gene2687	1.36e-12	70.0	COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,1ZJEB@1386|Bacillus	91061|Bacilli	IQ	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	PP-binding
HKD2_k127_6039360_1	1111479.AXAR01000008_gene2292	3.022e-205	652.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HE2B@91061|Bacilli	91061|Bacilli	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD2_k127_6039360_3	1174504.AJTN02000222_gene1433	3.839e-39	148.0	2FGYP@1|root,348TV@2|Bacteria,1VZPM@1239|Firmicutes,4HYBM@91061|Bacilli,1ZHW2@1386|Bacillus	91061|Bacilli	S	YokU-like protein, putative antitoxin	yokU	-	-	-	-	-	-	-	-	-	-	-	YokU
HKD2_k127_6039360_0	1174504.AJTN02000222_gene1432	3.553e-267	824.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,4HE2P@91061|Bacilli,1ZBET@1386|Bacillus	91061|Bacilli	E	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
HKD2_k127_6072664_5	1294265.JCM21738_3329	2.668e-16	78.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,1ZAWY@1386|Bacillus	91061|Bacilli	S	transport system, permease component	M1-957	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
HKD2_k127_6072664_3	1403313.AXBR01000002_gene4089	3.572e-61	213.0	COG1226@1|root,32UM6@2|Bacteria,1VC22@1239|Firmicutes,4HMGA@91061|Bacilli,1ZJ2P@1386|Bacillus	91061|Bacilli	P	Ion transport	-	-	-	ko:K08713	-	-	-	-	ko00000,ko02000	1.A.1.29.1	-	-	Ion_trans_2
HKD2_k127_6072664_2	1174504.AJTN02000238_gene531	5.84e-79	265.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli,1ZFKU@1386|Bacillus	91061|Bacilli	O	Peroxiredoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD2_k127_6072664_1	1403313.AXBR01000002_gene4085	2.822e-82	274.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,1ZFKE@1386|Bacillus	91061|Bacilli	P	Belongs to the Fur family	perR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD2_k127_6072664_4	1174504.AJTN02000238_gene527	5.84e-56	198.0	2C1CK@1|root,313Y4@2|Bacteria,1V6FR@1239|Firmicutes,4HIGI@91061|Bacilli,1ZGXQ@1386|Bacillus	91061|Bacilli	S	UPF0295 protein	ygzB	-	-	-	-	-	-	-	-	-	-	-	DUF2614
HKD2_k127_6072664_0	1403313.AXBR01000002_gene4083	8.853e-145	463.0	28IXS@1|root,2Z8VM@2|Bacteria,1TR3A@1239|Firmicutes,4HDYI@91061|Bacilli,1ZB0T@1386|Bacillus	91061|Bacilli	S	Nucleotidyltransferase-like	ygxA	-	-	-	-	-	-	-	-	-	-	-	NTF-like
HKD2_k127_6080841_5	666686.B1NLA3E_16350	8.786e-49	175.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD2_k127_6080841_0	1403313.AXBR01000008_gene648	2.743e-242	752.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli,1ZC7K@1386|Bacillus	91061|Bacilli	O	COG0826 Collagenase and related proteases	yrrO	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HKD2_k127_6080841_1	1403313.AXBR01000008_gene649	4.811e-164	520.0	COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus	91061|Bacilli	O	Peptidase U32	yrrN	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
HKD2_k127_6080841_3	1174504.AJTN02000236_gene489	2.271e-83	282.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli,1ZFK8@1386|Bacillus	91061|Bacilli	S	O-methyltransferase	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
HKD2_k127_6080841_2	1403313.AXBR01000008_gene651	7.643e-157	502.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,1ZC44@1386|Bacillus	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD2_k127_6080841_7	1174504.AJTN02000236_gene493	1.33e-42	157.0	COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,1ZI20@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0473 family	yrzB	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HKD2_k127_6080841_4	1403313.AXBR01000008_gene653	2.016e-75	255.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,1ZG6Y@1386|Bacillus	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD2_k127_6080841_6	1403313.AXBR01000008_gene654	2.017e-47	171.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,1ZHU7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
HKD2_k127_6080841_8	1174504.AJTN02000236_gene496	3.487e-14	72.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD2_k127_6126042_3	1168034.FH5T_08980	2.471e-05	48.0	COG3104@1|root,COG3104@2|Bacteria,4NIIT@976|Bacteroidetes,2FR16@200643|Bacteroidia	976|Bacteroidetes	E	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_6126042_2	880072.Desac_1498	2.656e-70	241.0	COG0664@1|root,COG0664@2|Bacteria,1N5RB@1224|Proteobacteria,42TH6@68525|delta/epsilon subdivisions,2WQZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD2_k127_6126042_0	880072.Desac_1499	2.233e-300	935.0	COG2204@1|root,COG3605@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3605@2|Bacteria,COG4191@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD2_k127_6126042_1	880072.Desac_1500	1.004e-248	773.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD2_k127_6178568_2	1403313.AXBR01000007_gene326	1.795e-61	217.0	COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,1ZFVJ@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ypmB	-	-	-	-	-	-	-	-	-	-	-	PepSY
HKD2_k127_6178568_0	1403313.AXBR01000007_gene328	2.169e-309	973.0	COG1199@1|root,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
HKD2_k127_6178568_1	1403313.AXBR01000007_gene329	9.772e-96	346.0	COG0847@1|root,COG0847@2|Bacteria,1UKF3@1239|Firmicutes,4ITIP@91061|Bacilli,1ZSCD@1386|Bacillus	91061|Bacilli	L	EXOIII	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
HKD2_k127_62500_3	1196031.ALEG01000013_gene45	9.347e-44	161.0	2D1ET@1|root,32TAJ@2|Bacteria,1V8Q4@1239|Firmicutes,4HQUW@91061|Bacilli,1ZI5D@1386|Bacillus	91061|Bacilli	S	Cell division protein FtsJ	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_62500_0	666686.B1NLA3E_01865	7.748e-48	174.0	2EBIP@1|root,335J4@2|Bacteria,1VJ9E@1239|Firmicutes,4HPA8@91061|Bacilli,1ZHZB@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3147
HKD2_k127_62500_2	796606.BMMGA3_02690	3.762e-45	166.0	arCOG03566@1|root,331ZR@2|Bacteria,1VFZ0@1239|Firmicutes,4HQV2@91061|Bacilli,1ZIDF@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3147
HKD2_k127_62500_1	1461580.CCAS010000047_gene3498	8.84e-47	179.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4HCVM@91061|Bacilli,1ZE91@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase, GGDEF domain	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
HKD2_k127_6254913_0	1131462.DCF50_p1102	7.271e-80	273.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,260BX@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
HKD2_k127_6254913_1	1123252.ATZF01000033_gene4324	3.076e-24	106.0	2E5FH@1|root,33077@2|Bacteria,1VH1Q@1239|Firmicutes,4HPD5@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6278540_2	1403313.AXBR01000010_gene944	4.515e-75	254.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,1ZBZY@1386|Bacillus	91061|Bacilli	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
HKD2_k127_6278540_3	997296.PB1_17009	9.889e-34	130.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus	91061|Bacilli	S	spore protein	B4168_3115	-	-	ko:K06419	-	-	-	-	ko00000	-	-	-	SASP
HKD2_k127_6278540_0	1403313.AXBR01000009_gene942	6.228e-274	850.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZCDC@1386|Bacillus	91061|Bacilli	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	ytcI	GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_6278540_1	1403313.AXBR01000009_gene940	3.738e-139	448.0	COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli,1ZD78@1386|Bacillus	91061|Bacilli	S	-transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
HKD2_k127_6278540_4	1403313.AXBR01000009_gene932	9.978e-21	93.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,1ZBTV@1386|Bacillus	91061|Bacilli	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
HKD2_k127_6313880_5	1174504.AJTN02000158_gene438	1.758e-46	169.0	COG0316@1|root,COG0316@2|Bacteria,1VB5R@1239|Firmicutes,4HKPI@91061|Bacilli,1ZGXR@1386|Bacillus	91061|Bacilli	S	Heme biosynthesis protein HemY	-	-	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	-
HKD2_k127_6313880_0	1403313.AXBR01000022_gene2822	1.534e-117	383.0	COG1028@1|root,COG1028@2|Bacteria,1U36W@1239|Firmicutes,4HAA8@91061|Bacilli,1ZBU4@1386|Bacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	fabG9	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD2_k127_6313880_3	1403313.AXBR01000002_gene4453	7.927e-65	226.0	COG0778@1|root,COG0778@2|Bacteria,1V6YR@1239|Firmicutes,4HIM7@91061|Bacilli,1ZRD8@1386|Bacillus	91061|Bacilli	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD2_k127_6313880_2	1033734.CAET01000058_gene1902	4.012e-82	278.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HD93@91061|Bacilli,1ZQ5R@1386|Bacillus	91061|Bacilli	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K11521	ko02020,map02020	M00465	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_6313880_1	666686.B1NLA3E_05245	8.219e-99	337.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,4ISRX@91061|Bacilli,1ZSCS@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD2_k127_6313880_6	1145276.T479_13410	1.081e-36	146.0	COG4097@1|root,COG4097@2|Bacteria,1VAMR@1239|Firmicutes,4HKN3@91061|Bacilli,3IZIR@400634|Lysinibacillus	91061|Bacilli	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
HKD2_k127_6313880_4	666686.B1NLA3E_05235	5.812e-58	208.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,1ZFHT@1386|Bacillus	91061|Bacilli	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD2_k127_6331732_1	1403313.AXBR01000021_gene3020	5.978e-223	695.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus	91061|Bacilli	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HKD2_k127_6331732_2	697284.ERIC2_c20840	1.594e-144	463.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli,26SQZ@186822|Paenibacillaceae	91061|Bacilli	C	ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
HKD2_k127_6331732_0	1403313.AXBR01000021_gene3016	4.006e-300	924.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus	91061|Bacilli	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD2_k127_6331732_4	1403313.AXBR01000021_gene3015	1.716e-66	229.0	COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli,1ZG72@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0342 family	ymcA	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	Com_YlbF
HKD2_k127_6331732_5	1340434.AXVA01000010_gene5484	2.909e-06	51.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6331732_3	1403313.AXBR01000021_gene3014	1.275e-96	317.0	2BYGR@1|root,2ZIKA@2|Bacteria,1V30V@1239|Firmicutes,4HFX6@91061|Bacilli,1ZE20@1386|Bacillus	91061|Bacilli	S	Spore coat protein	cotE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06328	-	-	-	-	ko00000	-	-	-	CotE
HKD2_k127_6356653_3	796606.BMMGA3_08595	1.37e-88	295.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_6356653_6	279010.BL00800	2.484e-26	114.0	2EAKH@1|root,334P5@2|Bacteria,1VMKG@1239|Firmicutes,4HNTF@91061|Bacilli,1ZIU0@1386|Bacillus	91061|Bacilli	S	YolD-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YolD
HKD2_k127_6356653_1	1403313.AXBR01000010_gene981	4.851e-205	645.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,1ZCHH@1386|Bacillus	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	iYO844.BSU04360	Nramp
HKD2_k127_6356653_0	1403313.AXBR01000007_gene449	1.8e-224	700.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,1ZC8I@1386|Bacillus	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB2	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD2_k127_6356653_2	1403313.AXBR01000007_gene450	1.225e-105	346.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HEC8@91061|Bacilli,1ZDXR@1386|Bacillus	91061|Bacilli	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,NLPC_P60
HKD2_k127_6356653_4	1403313.AXBR01000007_gene451	3.788e-52	189.0	29QVU@1|root,30BW3@2|Bacteria,1U8RK@1239|Firmicutes,4IIPR@91061|Bacilli,1ZIU5@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6356653_5	1347369.CCAD010000062_gene4038	2.148e-28	123.0	2C1ZI@1|root,32YBF@2|Bacteria,1VHYA@1239|Firmicutes,4I0ES@91061|Bacilli,1ZIHG@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6356653_7	555088.DealDRAFT_3162	2.195e-10	64.0	2B68X@1|root,31Z68@2|Bacteria,1V93N@1239|Firmicutes,24PDD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6376662_1	1403313.AXBR01000008_gene583	6.538e-101	331.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,1ZAV8@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD2_k127_6376662_0	1403313.AXBR01000008_gene584	0.0	1039.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,1ZC16@1386|Bacillus	91061|Bacilli	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HKD2_k127_6376662_2	1403313.AXBR01000008_gene585	1.245e-61	214.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,1ZFK7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0178 family	yqxD	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HKD2_k127_6380951_4	1403313.AXBR01000002_gene4371	1.327e-197	627.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus	91061|Bacilli	V	ABC transporter	malQ	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_6380951_2	1174504.AJTN02000185_gene128	8.314e-259	811.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	yfiC3	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_6380951_3	1403313.AXBR01000002_gene4367	4.774e-228	710.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus	91061|Bacilli	P	Ammonium transporter	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iYO844.BSU36510	Ammonium_transp
HKD2_k127_6380951_9	1403313.AXBR01000002_gene4366	3.281e-55	195.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HM5G@91061|Bacilli,1ZGHT@1386|Bacillus	91061|Bacilli	K	Belongs to the P(II) protein family	nrgB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HKD2_k127_6380951_6	1174504.AJTN02000185_gene110	3.115e-96	319.0	COG3279@1|root,COG3279@2|Bacteria,1UGZ1@1239|Firmicutes,4HD88@91061|Bacilli,1ZD1A@1386|Bacillus	91061|Bacilli	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HKD2_k127_6380951_0	1403313.AXBR01000002_gene4363	6.404e-277	857.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4HAI5@91061|Bacilli,1ZDN1@1386|Bacillus	91061|Bacilli	C	Acetyl-CoA hydrolase/transferase N-terminal domain	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD2_k127_6380951_5	1196029.ALIM01000014_gene3628	8.107e-145	467.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZCDX@1386|Bacillus	91061|Bacilli	S	transporter activity	yueF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD2_k127_6380951_1	1403313.AXBR01000002_gene4361	7.891e-262	811.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_6380951_7	1122918.KB907259_gene793	1.341e-75	273.0	COG0840@1|root,COG0840@2|Bacteria,1V3KN@1239|Firmicutes,4HGZS@91061|Bacilli,26VPP@186822|Paenibacillaceae	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
HKD2_k127_6380951_8	1403313.AXBR01000002_gene4358	3.41e-75	256.0	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1V6Q8@1239|Firmicutes,4HKAY@91061|Bacilli,1ZDSB@1386|Bacillus	91061|Bacilli	M	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D,LysM
HKD2_k127_6388343_1	1121091.AUMP01000048_gene1299	1.333e-174	556.0	28HKD@1|root,2Z7V8@2|Bacteria,1TQV8@1239|Firmicutes,4IUCG@91061|Bacilli	91061|Bacilli	S	type ii restriction enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6388343_4	665959.HMPREF1013_03966	1.65e-53	190.0	COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,4HIWV@91061|Bacilli,1ZIM7@1386|Bacillus	91061|Bacilli	C	COG1145 Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
HKD2_k127_6388343_2	1196029.ALIM01000019_gene4100	1.655e-74	254.0	COG1388@1|root,COG1388@2|Bacteria,1V3Q9@1239|Firmicutes,4HH9X@91061|Bacilli,1ZGK9@1386|Bacillus	91061|Bacilli	M	Protein of unknown function (DUF1541)	ydhK	-	-	-	-	-	-	-	-	-	-	-	DUF1541
HKD2_k127_6388343_0	665959.HMPREF1013_05669	8.425e-216	677.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli,1ZBQK@1386|Bacillus	91061|Bacilli	V	Mate efflux family protein	XK27_04615	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD2_k127_6388343_5	665959.HMPREF1013_05670	2.152e-43	159.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,4ICC5@91061|Bacilli,1ZJTT@1386|Bacillus	91061|Bacilli	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
HKD2_k127_6388343_3	997296.PB1_12434	1.101e-65	226.0	COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,1ZBEQ@1386|Bacillus	91061|Bacilli	Q	Multi-copper	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD2_k127_6416884_3	1403313.AXBR01000017_gene3612	2.557e-05	46.0	2B1Y6@1|root,31UEI@2|Bacteria,1V85P@1239|Firmicutes,4HJP9@91061|Bacilli,1ZG3J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD2_k127_6416884_0	1403313.AXBR01000017_gene3610	8.059e-181	572.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HBTP@91061|Bacilli,1ZATT@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	ydbM	-	-	-	-	-	-	-	-	-	-	iYO844.BSU04520	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_6416884_2	1211814.CAPG01000028_gene1390	1.405e-05	48.0	COG3223@1|root,COG3223@2|Bacteria,1V9CG@1239|Firmicutes,4HIMW@91061|Bacilli,1ZR28@1386|Bacillus	91061|Bacilli	S	Phosphate-starvation-inducible E	psiE	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
HKD2_k127_6416884_1	1227360.C176_11289	2.573e-36	137.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,26FTN@186818|Planococcaceae	91061|Bacilli	K	'Cold-shock' DNA-binding domain	cspL	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_6430742_0	1122947.FR7_2122	1.1e-320	985.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4H2N7@909932|Negativicutes	909932|Negativicutes	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD2_k127_6430742_2	1122947.FR7_2121	2.641e-21	96.0	2DTV1@1|root,33MS4@2|Bacteria,1VNBG@1239|Firmicutes,4H66P@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6430742_1	935836.JAEL01000024_gene2448	1.128e-106	351.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,1ZBUF@1386|Bacillus	91061|Bacilli	S	Oxidoreductase	yulF	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114,GO:0102497	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
HKD2_k127_6431048_0	484770.UFO1_3975	0.0	1026.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes	1239|Firmicutes	E	Oligoendopeptidase M3 Family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
HKD2_k127_6434991_0	1227360.C176_14112	7.423e-205	653.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26GM0@186818|Planococcaceae	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	tlpA3	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
HKD2_k127_6434991_1	86416.Clopa_1091	1.358e-119	387.0	COG1741@1|root,COG1741@2|Bacteria,1TSV4@1239|Firmicutes,25D4Z@186801|Clostridia,36U76@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD2_k127_6434991_2	1340434.AXVA01000010_gene5484	2.507e-05	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6452511_3	1120998.AUFC01000022_gene448	2.799e-80	271.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes	1239|Firmicutes	U	Belongs to the peptidase S26 family	sipT	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD2_k127_6452511_1	1120998.AUFC01000022_gene449	1.281e-84	284.0	COG0681@1|root,COG0681@2|Bacteria,1V6R3@1239|Firmicutes,25CN6@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD2_k127_6452511_0	1120998.AUFC01000022_gene450	5.029e-90	299.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,3WDCY@538999|Clostridiales incertae sedis	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD2_k127_6452511_2	1120998.AUFC01000022_gene451	9.526e-81	270.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WD56@538999|Clostridiales incertae sedis	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD2_k127_6452511_4	1220589.CD32_00460	8.661e-05	46.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HF0S@91061|Bacilli,3J02T@400634|Lysinibacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
HKD2_k127_6459800_0	1444310.JANV01000166_gene4423	1.097e-110	373.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	epr	GO:0005575,GO:0005576	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	A2M_N,CW_binding_2,Peptidase_S8,SLH
HKD2_k127_6459800_4	1384049.CD29_13595	7.093e-05	47.0	2EUZZ@1|root,33NF5@2|Bacteria,1VNDJ@1239|Firmicutes,4HRD5@91061|Bacilli,3IZW1@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6459800_3	1423755.BAML01000008_gene690	2.032e-23	111.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,3F6Y9@33958|Lactobacillaceae	91061|Bacilli	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HKD2_k127_6459800_1	1131730.BAVI_22888	8.203e-81	274.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZIEP@1386|Bacillus	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	pgpB3	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_6459800_2	1403313.AXBR01000027_gene5312	1.716e-77	260.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
HKD2_k127_6504573_2	796606.BMMGA3_10440	1.868e-218	683.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,1ZAUK@1386|Bacillus	91061|Bacilli	F	xanthine	pbuX	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823	-	ko:K16169	-	-	-	-	ko00000,ko02000	2.A.40.3.1	-	-	Xan_ur_permease
HKD2_k127_6504573_5	1380763.BG53_11090	4.776e-26	109.0	2EKZS@1|root,33EP8@2|Bacteria,1VPEE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6504573_1	698769.JFBD01000019_gene1979	3.331e-232	724.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HBV3@91061|Bacilli,4C604@84406|Virgibacillus	91061|Bacilli	F	Amidohydrolase family	mtaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD2_k127_6504573_3	1196031.ALEG01000008_gene5059	1.375e-124	401.0	COG1878@1|root,COG1878@2|Bacteria,1UZ93@1239|Firmicutes,4IRAF@91061|Bacilli,1ZRSX@1386|Bacillus	91061|Bacilli	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
HKD2_k127_6504573_0	935836.JAEL01000013_gene4532	6.833e-270	835.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4I8V8@91061|Bacilli,1ZE9Z@1386|Bacillus	91061|Bacilli	F	Adenine deaminase C-terminal domain	-	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD2_k127_6506201_0	436308.Nmar_1393	1.411e-51	191.0	COG0164@1|root,arCOG04121@2157|Archaea,41SK9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD2_k127_6506201_2	1183377.Py04_1504	0.0004875	53.0	COG1378@1|root,arCOG02038@2157|Archaea,2Y64T@28890|Euryarchaeota,242RJ@183968|Thermococci	183968|Thermococci	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
HKD2_k127_6506201_3	877455.Metbo_2401	0.0009163	43.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,23NS2@183925|Methanobacteria	183925|Methanobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
HKD2_k127_6515162_0	1033734.CAET01000077_gene2924	8.277e-189	595.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus	91061|Bacilli	E	COG2195 Di- and tripeptidases	yqjE	-	3.4.11.14,3.4.11.4	ko:K01258,ko:K01263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD2_k127_6515162_1	315749.Bcer98_2840	1.045e-141	463.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,1ZAZZ@1386|Bacillus	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD2_k127_6515162_2	1396.DJ87_717	2.901e-102	335.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus	91061|Bacilli	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
HKD2_k127_6584772_5	760192.Halhy_4976	4.778e-10	65.0	28PN6@1|root,2ZCB1@2|Bacteria,4NN1Q@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
HKD2_k127_6584772_1	871968.DESME_05285	4.688e-186	586.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,LTD
HKD2_k127_6584772_3	871968.DESME_05290	5.433e-55	194.0	COG2940@1|root,COG2940@2|Bacteria,1V4EX@1239|Firmicutes	1239|Firmicutes	S	Lysine methyltransferase	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD2_k127_6584772_6	796606.BMMGA3_09475	0.0001147	45.0	COG1131@1|root,COG1131@2|Bacteria,1TRM5@1239|Firmicutes,4HFBN@91061|Bacilli,1ZCK0@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	yvfR	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_6584772_2	1169144.KB910926_gene1136	8.615e-98	329.0	COG1807@1|root,COG1807@2|Bacteria,1V114@1239|Firmicutes,4HB64@91061|Bacilli,1ZDJ4@1386|Bacillus	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD2_k127_6589695_5	1294265.JCM21738_851	1.89e-38	149.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,1ZBJ4@1386|Bacillus	91061|Bacilli	M	biosynthesis protein	ywqC	-	-	-	-	-	-	-	-	-	-	-	Wzz
HKD2_k127_6589695_4	1131730.BAVI_17127	2.674e-69	242.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,1ZB83@1386|Bacillus	91061|Bacilli	D	COG0489 ATPases involved in chromosome partitioning	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA
HKD2_k127_6589695_0	1117379.BABA_10111	6.43e-293	909.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli,1ZB9K@1386|Bacillus	91061|Bacilli	GM	Polysaccharide biosynthesis protein	pglF	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	-	ko:K19421	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Polysacc_synt_2
HKD2_k127_6589695_1	1196031.ALEG01000067_gene4776	1.295e-165	523.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD2_k127_6589695_2	1122915.AUGY01000047_gene1417	2.045e-161	516.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,4HCN6@91061|Bacilli,26VRM@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase 4-like	epsD	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
HKD2_k127_6589695_3	1449063.JMLS01000021_gene818	2.025e-70	243.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli,26UTQ@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_6594001_1	1499680.CCFE01000018_gene1414	8.694e-09	59.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes	1239|Firmicutes	T	COG3629 DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
HKD2_k127_6594001_0	1499680.CCFE01000018_gene1418	2.087e-177	559.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,4HBQZ@91061|Bacilli	91061|Bacilli	E	glutamate	ftcD	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
HKD2_k127_6594001_2	1499680.CCFE01000018_gene1420	2.273e-08	56.0	COG3404@1|root,COG3404@2|Bacteria,1U465@1239|Firmicutes,4IK7Q@91061|Bacilli,1ZNJY@1386|Bacillus	91061|Bacilli	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
HKD2_k127_6619891_2	1403313.AXBR01000009_gene921	3.079e-212	662.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,1ZC1P@1386|Bacillus	91061|Bacilli	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
HKD2_k127_6619891_0	1403313.AXBR01000009_gene920	3.444e-266	823.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,1ZD3C@1386|Bacillus	91061|Bacilli	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HKD2_k127_6619891_7	1403313.AXBR01000009_gene919	1.543e-61	215.0	COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,1ZGY4@1386|Bacillus	91061|Bacilli	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD2_k127_6619891_4	1403313.AXBR01000009_gene917	7.483e-168	534.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HKD2_k127_6619891_5	1403313.AXBR01000009_gene916	3.176e-112	366.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,1ZBI0@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0173 family	ytkL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
HKD2_k127_6619891_9	1403313.AXBR01000009_gene914	1.113e-19	90.0	2BPSH@1|root,32IJT@2|Bacteria,1UAV1@1239|Firmicutes,4IM7V@91061|Bacilli,1ZJFD@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6619891_1	1403313.AXBR01000009_gene913	3.343e-253	784.0	COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,1ZB1Q@1386|Bacillus	91061|Bacilli	K	transcriptional regulator containing CBS domains	ytoI	-	-	-	-	-	-	-	-	-	-	-	4HBT,CBS,DRTGG,GntR,HTH_24
HKD2_k127_6619891_8	1403313.AXBR01000009_gene912	4.868e-40	151.0	2E1U1@1|root,32X3Q@2|Bacteria,1VD0Y@1239|Firmicutes,4HNCK@91061|Bacilli,1ZHYC@1386|Bacillus	91061|Bacilli	S	YtpI-like protein	ytpI	-	-	-	-	-	-	-	-	-	-	-	YtpI
HKD2_k127_6619891_3	1403313.AXBR01000009_gene911	1.849e-168	533.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,1ZB08@1386|Bacillus	91061|Bacilli	S	COG0618 Exopolyphosphatase-related proteins	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD2_k127_6619891_6	871968.DESME_03805	1.474e-62	220.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,2605N@186807|Peptococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	-	-	-	ko:K03442,ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.4	-	-	MS_channel
HKD2_k127_6621512_5	1280681.AUJZ01000015_gene2097	5.441e-05	46.0	COG4641@1|root,COG4641@2|Bacteria,1VQPW@1239|Firmicutes,25KMM@186801|Clostridia,4BY3Q@830|Butyrivibrio	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
HKD2_k127_6621512_1	1236973.JCM9157_2080	2.685e-159	505.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,1ZAWH@1386|Bacillus	91061|Bacilli	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA2	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD2_k127_6621512_3	1234664.AMRO01000071_gene2960	2.223e-95	315.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli,1WH85@129337|Geobacillus	91061|Bacilli	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
HKD2_k127_6621512_0	1234664.AMRO01000071_gene2959	6.7e-201	627.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1WHF3@129337|Geobacillus	91061|Bacilli	M	Male sterility protein	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD2_k127_6621512_2	1234664.AMRO01000071_gene2958	2.014e-129	419.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,1WHFR@129337|Geobacillus	91061|Bacilli	M	Male sterility protein	spsK	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD2_k127_6621512_4	1169144.KB910929_gene1845	8.342e-53	192.0	COG4733@1|root,COG4733@2|Bacteria,1UP2U@1239|Firmicutes,4IUZ7@91061|Bacilli,1ZSI1@1386|Bacillus	91061|Bacilli	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3238
HKD2_k127_6625434_3	1403313.AXBR01000013_gene1309	4.068e-141	459.0	COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,1ZC95@1386|Bacillus	91061|Bacilli	S	Putative adhesin	yvlB	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HKD2_k127_6625434_0	1403313.AXBR01000013_gene1308	0.0	1697.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HKD2_k127_6625434_1	1403313.AXBR01000013_gene1307	0.0	1171.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,1ZC50@1386|Bacillus	91061|Bacilli	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HKD2_k127_6625434_5	1403313.AXBR01000013_gene1306	4.723e-27	111.0	COG4897@1|root,COG4897@2|Bacteria,1VMTY@1239|Firmicutes,4HRU1@91061|Bacilli,1ZQIK@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2198)	csbA	-	-	-	-	-	-	-	-	-	-	-	DUF2198
HKD2_k127_6625434_4	1174504.AJTN02000230_gene1208	1.416e-108	370.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
HKD2_k127_6625434_2	1403313.AXBR01000013_gene1304	0.0	1112.0	COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4H9XX@91061|Bacilli,1ZQAJ@1386|Bacillus	91061|Bacilli	S	MMPL domain protein	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD2_k127_6625434_6	1403313.AXBR01000013_gene1303	8.999e-21	92.0	COG2353@1|root,COG2353@2|Bacteria,1V1NX@1239|Firmicutes,4HFXF@91061|Bacilli,1ZCU9@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD2_k127_6721456_0	1132442.KB889753_gene120	0.0	1817.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD2_k127_6721456_3	1121381.JNIV01000017_gene1055	2.423e-08	58.0	COG0365@1|root,COG0365@2|Bacteria,1WI8W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD2_k127_6721456_6	1122221.JHVI01000001_gene1833	0.0005997	43.0	COG0365@1|root,COG0365@2|Bacteria,1WIHG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD2_k127_6721456_5	935565.JAEM01000028_gene923	0.0001209	45.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2VFPQ@28211|Alphaproteobacteria,2PZ6V@265|Paracoccus	1224|Proteobacteria	I	N-terminal half of MaoC dehydratase	-	-	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
HKD2_k127_6721456_4	1340434.AXVA01000010_gene5484	2.897e-06	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6721456_2	326423.RBAM_027780	1.3e-27	113.0	COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,1ZB3B@1386|Bacillus	91061|Bacilli	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD2_k127_6721456_1	768704.Desmer_1632	1.566e-120	398.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,260GQ@186807|Peptococcaceae	186801|Clostridia	KT	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_8,PAS_9,Sigma54_activat
HKD2_k127_6727437_0	1034769.KB910518_gene4272	2.801e-73	252.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,26SGR@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD2_k127_6727437_2	574376.BAMA_09900	9.363e-48	175.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,1ZQCE@1386|Bacillus	91061|Bacilli	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	napA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD2_k127_6727437_1	218284.CCDN010000009_gene4309	2.253e-62	220.0	2EIP2@1|root,33CEF@2|Bacteria,1TW5W@1239|Firmicutes,4I4WN@91061|Bacilli,1ZCQ8@1386|Bacillus	91061|Bacilli	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
HKD2_k127_6738994_1	1246626.BleG1_0360	5.093e-79	277.0	COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HCW1@91061|Bacilli,1ZDKH@1386|Bacillus	91061|Bacilli	S	drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD2_k127_6738994_2	265729.GS18_0201685	2.263e-44	168.0	COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,4HH86@91061|Bacilli,1ZFSK@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HKD2_k127_6738994_4	365659.smi_1713	5.272e-30	123.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,4HD54@91061|Bacilli,2TPQ0@28037|Streptococcus mitis	91061|Bacilli	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD2_k127_6738994_3	1408422.JHYF01000021_gene961	2.719e-40	153.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,36ECD@31979|Clostridiaceae	186801|Clostridia	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD2_k127_6738994_0	1403313.AXBR01000002_gene4237	3.221e-161	510.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZD4Q@1386|Bacillus	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA_1	-	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	TRAM,tRNA_U5-meth_tr
HKD2_k127_6764601_1	1174504.AJTN02000162_gene1597	5.874e-84	278.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,1ZBDK@1386|Bacillus	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HKD2_k127_6764601_2	1403313.AXBR01000029_gene5114	8.216e-54	190.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,1ZGZI@1386|Bacillus	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
HKD2_k127_6764601_0	1403313.AXBR01000029_gene5115	2.234e-307	948.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus	91061|Bacilli	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD2_k127_6779090_0	1384049.CD29_08560	1.887e-143	459.0	COG1680@1|root,COG1680@2|Bacteria,1TRPT@1239|Firmicutes,4HG2G@91061|Bacilli,3IX2C@400634|Lysinibacillus	91061|Bacilli	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2	-	-	ABC_membrane,ABC_tran,Beta-lactamase
HKD2_k127_6779090_1	1384049.CD29_15180	4.836e-110	358.0	COG3751@1|root,COG3751@2|Bacteria,1UNHV@1239|Firmicutes,4HEJV@91061|Bacilli,3IZJ3@400634|Lysinibacillus	91061|Bacilli	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
HKD2_k127_6787180_1	1123511.KB905841_gene1309	3.07e-104	353.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H36N@909932|Negativicutes	909932|Negativicutes	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
HKD2_k127_6787180_0	1122947.FR7_3052	2.017e-158	502.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4H2V6@909932|Negativicutes	909932|Negativicutes	K	PFAM LysR substrate-binding protein, regulatory protein LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_6787180_2	1120985.AUMI01000011_gene380	2.945e-12	68.0	COG2199@1|root,COG2199@2|Bacteria,1TT99@1239|Firmicutes,4H5MT@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HKD2_k127_6787257_0	1461580.CCAS010000001_gene108	2.707e-220	687.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	-	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,MFS_1_like,Sugar_tr
HKD2_k127_6787257_1	1403313.AXBR01000001_gene3944	1.53e-139	448.0	COG1723@1|root,COG1723@2|Bacteria,1TQMD@1239|Firmicutes,4I6H2@91061|Bacilli,1ZEBB@1386|Bacillus	91061|Bacilli	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
HKD2_k127_6807020_2	1403313.AXBR01000002_gene4208	9.685e-162	512.0	COG0583@1|root,COG0583@2|Bacteria,1UXY9@1239|Firmicutes,4HEXP@91061|Bacilli,1ZB03@1386|Bacillus	91061|Bacilli	K	COG0583 Transcriptional regulator	lysR1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_6807020_3	1403313.AXBR01000002_gene4449	2.391e-83	293.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,1V0AI@1239|Firmicutes,4HDZZ@91061|Bacilli,1ZEHB@1386|Bacillus	91061|Bacilli	P	protein, homolog of Cu resistance protein CopC	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,YtkA
HKD2_k127_6807020_7	1307436.PBF_15464	2.722e-10	62.0	29S7K@1|root,30DC2@2|Bacteria,1UB4J@1239|Firmicutes,4IMH5@91061|Bacilli,1ZK58@1386|Bacillus	91061|Bacilli	S	YhfH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhfH
HKD2_k127_6807020_6	941639.BCO26_0959	5.533e-11	64.0	29S7K@1|root,30DC2@2|Bacteria,1UB4J@1239|Firmicutes,4IMH5@91061|Bacilli,1ZK58@1386|Bacillus	91061|Bacilli	S	YhfH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhfH
HKD2_k127_6807020_5	941639.BCO26_0959	2.978e-14	73.0	29S7K@1|root,30DC2@2|Bacteria,1UB4J@1239|Firmicutes,4IMH5@91061|Bacilli,1ZK58@1386|Bacillus	91061|Bacilli	S	YhfH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhfH
HKD2_k127_6807020_1	1403313.AXBR01000025_gene4913	3.675e-195	616.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus	91061|Bacilli	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD2_k127_6807020_0	1403313.AXBR01000025_gene4914	0.0	1070.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus	91061|Bacilli	P	COG2217 Cation transport ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD2_k127_6807020_4	1034347.CAHJ01000071_gene2754	1.83e-50	181.0	COG0640@1|root,COG0640@2|Bacteria,1VFNB@1239|Firmicutes,4HQ6G@91061|Bacilli,1ZQGP@1386|Bacillus	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	cadC	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HKD2_k127_6807020_8	1340434.AXVA01000010_gene5484	2.897e-06	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6807080_0	935845.JADQ01000060_gene9	1.428e-169	536.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,26S2B@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_6807080_2	1347369.CCAD010000066_gene3651	8.461e-13	70.0	28QDF@1|root,2ZCVT@2|Bacteria,1W26C@1239|Firmicutes,4HZHE@91061|Bacilli,1ZKAN@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6807080_1	1196029.ALIM01000013_gene4055	1.206e-85	286.0	28I0M@1|root,2ZATW@2|Bacteria,1UZIU@1239|Firmicutes,4HCZK@91061|Bacilli,1ZC7Y@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3231
HKD2_k127_6812460_5	1461580.CCAS010000032_gene2881	5.932e-16	79.0	2DFJN@1|root,2ZS4E@2|Bacteria,1W278@1239|Firmicutes,4HZWP@91061|Bacilli,1ZK2E@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3934
HKD2_k127_6812460_0	1405.DJ92_738	7.682e-83	290.0	COG0477@1|root,COG2814@2|Bacteria,1TPVC@1239|Firmicutes,4HB6R@91061|Bacilli,1ZS47@1386|Bacillus	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	ko:K08152	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1,Sugar_tr
HKD2_k127_6812460_3	1121091.AUMP01000031_gene1422	2.462e-51	193.0	COG0697@1|root,COG0697@2|Bacteria,1TTAY@1239|Firmicutes,4HD1U@91061|Bacilli	91061|Bacilli	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_6812460_4	1341151.ASZU01000016_gene794	8.679e-50	188.0	COG0583@1|root,COG0583@2|Bacteria,1VBN9@1239|Firmicutes,4I31H@91061|Bacilli,27CDM@186824|Thermoactinomycetaceae	91061|Bacilli	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_6812460_1	1131730.BAVI_01869	4.659e-82	276.0	COG3216@1|root,COG3216@2|Bacteria,1VG1T@1239|Firmicutes,4HNPX@91061|Bacilli,1ZE24@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
HKD2_k127_6812460_2	1131730.BAVI_08946	3.347e-72	246.0	COG3325@1|root,COG3325@2|Bacteria,1UPJ7@1239|Firmicutes,4HBA7@91061|Bacilli,1ZDN6@1386|Bacillus	91061|Bacilli	G	Glycoside Hydrolase Family 18	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_2,CBM_5_12,Glyco_hydro_18,fn3
HKD2_k127_6835472_1	1403313.AXBR01000002_gene4237	6.056e-85	283.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZD4Q@1386|Bacillus	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA_1	-	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	TRAM,tRNA_U5-meth_tr
HKD2_k127_6835472_4	1174504.AJTN02000154_gene943	1.024e-16	80.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,1ZCV5@1386|Bacillus	91061|Bacilli	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	yfjP	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HKD2_k127_6835472_5	1403313.AXBR01000002_gene4238	5.436e-12	67.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,1ZCV5@1386|Bacillus	91061|Bacilli	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	yfjP	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HKD2_k127_6835472_3	1117379.BABA_00455	2.355e-28	117.0	29T2F@1|root,30E8Y@2|Bacteria,1UC9G@1239|Firmicutes,4INRW@91061|Bacilli,1ZNUT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6835472_2	1117379.BABA_00460	5.866e-31	122.0	29S6P@1|root,30DB7@2|Bacteria,1UB3N@1239|Firmicutes,4IMG9@91061|Bacilli,1ZK3B@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6835472_0	1403313.AXBR01000002_gene4239	1.807e-133	428.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,4HAQI@91061|Bacilli,1ZBYP@1386|Bacillus	91061|Bacilli	G	deacetylase	pdaA	GO:0005575,GO:0016020	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HKD2_k127_68372_0	1174504.AJTN02000200_gene3516	8.425e-274	851.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,1ZATE@1386|Bacillus	91061|Bacilli	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HKD2_k127_68372_8	1403313.AXBR01000013_gene1488	1.752e-104	344.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,1ZEEI@1386|Bacillus	91061|Bacilli	T	COG1734 DnaK suppressor protein	yteA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
HKD2_k127_68372_14	1403313.AXBR01000013_gene1484	1.015e-15	78.0	2EG47@1|root,339W6@2|Bacteria,1VMG4@1239|Firmicutes,4HRAK@91061|Bacilli,1ZK0D@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_68372_5	1403313.AXBR01000013_gene1483	2.359e-112	364.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,1ZBBP@1386|Bacillus	91061|Bacilli	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HKD2_k127_68372_11	1403313.AXBR01000013_gene1482	3.583e-44	164.0	2DNAX@1|root,32UIM@2|Bacteria,1VATB@1239|Firmicutes,4HKG4@91061|Bacilli,1ZGXU@1386|Bacillus	91061|Bacilli	G	Kinase associated protein B	kapB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06347	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	KapB
HKD2_k127_68372_6	1403313.AXBR01000013_gene1481	3.264e-112	364.0	COG5018@1|root,COG5018@2|Bacteria,1TT8A@1239|Firmicutes,4HFEZ@91061|Bacilli,1ZBWS@1386|Bacillus	91061|Bacilli	L	Inhibitor of the KinA pathway	kapD	-	-	ko:K06348	-	-	-	-	ko00000	-	-	-	RNase_T
HKD2_k127_68372_1	1174504.AJTN02000200_gene3523	1.269e-236	746.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus	91061|Bacilli	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD2_k127_68372_10	1174504.AJTN02000200_gene3524	8.679e-60	212.0	2CIBU@1|root,30GF5@2|Bacteria,1V4EG@1239|Firmicutes,4HH80@91061|Bacilli,1ZGKU@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5366)	yufK	-	-	-	-	-	-	-	-	-	-	-	DUF5366
HKD2_k127_68372_7	1243664.CAVL020000054_gene2959	1.775e-107	359.0	COG0654@1|root,COG0654@2|Bacteria,1UZNW@1239|Firmicutes,4HB88@91061|Bacilli,1ZRUT@1386|Bacillus	91061|Bacilli	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HKD2_k127_68372_9	1403313.AXBR01000013_gene1469	3.822e-86	289.0	COG5663@1|root,COG5663@2|Bacteria,1V1H4@1239|Firmicutes,4HFXX@91061|Bacilli,1ZFJK@1386|Bacillus	91061|Bacilli	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
HKD2_k127_68372_3	1384049.CD29_11500	4.752e-163	520.0	COG0654@1|root,COG0654@2|Bacteria,1U29G@1239|Firmicutes,4HF0P@91061|Bacilli,3IXBF@400634|Lysinibacillus	91061|Bacilli	CH	FAD-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HKD2_k127_68372_2	1403313.AXBR01000013_gene1467	2.18e-191	602.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,1ZBTJ@1386|Bacillus	91061|Bacilli	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD2_k127_68372_4	1403313.AXBR01000013_gene1466	2.349e-127	410.0	COG0807@1|root,COG0807@2|Bacteria,1TRVI@1239|Firmicutes,4HBFF@91061|Bacilli,1ZBTW@1386|Bacillus	91061|Bacilli	H	GTP cyclohydrolase II	-	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
HKD2_k127_68372_13	1174504.AJTN02000200_gene3535	8.705e-19	86.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus	91061|Bacilli	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HKD2_k127_6845698_0	1196322.A370_00234	3.113e-163	522.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,36EMB@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_6845698_2	1540257.JQMW01000009_gene2852	1.519e-44	166.0	COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,24IJX@186801|Clostridia,36WYT@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD2_k127_6845698_1	1033734.CAET01000056_gene1358	3.853e-119	402.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	tlpA1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
HKD2_k127_6846336_0	1403313.AXBR01000027_gene5319	4.681e-189	593.0	COG4972@1|root,COG4972@2|Bacteria,1TSTJ@1239|Firmicutes,4HD01@91061|Bacilli,1ZCYF@1386|Bacillus	91061|Bacilli	NU	Pilus assembly protein	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
HKD2_k127_6846336_2	1403313.AXBR01000027_gene5318	4.278e-58	206.0	294NZ@1|root,2ZS2A@2|Bacteria,1V3ME@1239|Firmicutes,4HHEZ@91061|Bacilli,1ZFT3@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6846336_1	1403313.AXBR01000027_gene5316	3.827e-188	599.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBVK@91061|Bacilli,1ZBPB@1386|Bacillus	91061|Bacilli	L	DEAD DEAH box helicase	deaD3	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
HKD2_k127_6846336_3	1157490.EL26_02485	1.256e-15	78.0	COG3173@1|root,COG3173@2|Bacteria,1V2AK@1239|Firmicutes,4HFXB@91061|Bacilli,279TH@186823|Alicyclobacillaceae	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
HKD2_k127_6846336_4	935837.JAEK01000024_gene1069	3.005e-12	66.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes,4IMUS@91061|Bacilli,1ZKVY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6847992_10	218284.CCDN010000002_gene2903	3.403e-49	176.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus	91061|Bacilli	S	COG2270 Permeases of the major facilitator superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD2_k127_6847992_4	582744.Msip34_0014	3.635e-136	461.0	COG2202@1|root,COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
HKD2_k127_6847992_7	218284.CCDN010000002_gene2898	2.888e-105	350.0	COG0697@1|root,COG0697@2|Bacteria,1TR8G@1239|Firmicutes,4HCXB@91061|Bacilli,1ZC8D@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_6847992_1	1403313.AXBR01000028_gene5042	3.452e-250	777.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.2,1.4.1.4	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD2_k127_6847992_5	1403313.AXBR01000028_gene5041	6.133e-133	429.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HA1X@91061|Bacilli,1ZCDN@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	gltC	-	-	ko:K09681	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HKD2_k127_6847992_12	1340434.AXVA01000010_gene5484	7.273e-11	68.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6847992_2	1403313.AXBR01000028_gene5039	1.723e-210	658.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,1ZBVG@1386|Bacillus	91061|Bacilli	J	Methyltransferase	ywbD	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HKD2_k127_6847992_8	1403313.AXBR01000028_gene5035	5.696e-102	338.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,1ZBTT@1386|Bacillus	91061|Bacilli	S	Putative threonine/serine exporter	yjjP	-	-	-	-	-	-	-	-	-	-	-	ThrE
HKD2_k127_6847992_9	1403313.AXBR01000028_gene5034	2.126e-50	182.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,1ZH5J@1386|Bacillus	91061|Bacilli	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
HKD2_k127_6847992_0	1403313.AXBR01000028_gene5033	8.77e-272	843.0	COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,4HCF6@91061|Bacilli,1ZCX7@1386|Bacillus	91061|Bacilli	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	ywcA	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
HKD2_k127_6847992_11	1403313.AXBR01000028_gene5032	3.7e-36	139.0	COG3162@1|root,COG3162@2|Bacteria,1VAEW@1239|Firmicutes,4HM0S@91061|Bacilli,1ZHX2@1386|Bacillus	91061|Bacilli	S	Protein of unknown function, DUF485	ywcB	-	-	-	-	-	-	-	-	-	-	-	DUF485
HKD2_k127_6847992_6	1403313.AXBR01000028_gene5027	1.31e-115	375.0	COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli,1ZDYN@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_6847992_3	1403313.AXBR01000028_gene5026	4.252e-186	589.0	COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli,1ZBNV@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD2_k127_6848941_1	1034347.CAHJ01000070_gene2634	2.424e-115	374.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus	91061|Bacilli	P	P-type ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD2_k127_6848941_3	1408303.JNJJ01000057_gene1324	6.868e-07	51.0	29TAC@1|root,30EHD@2|Bacteria,1UCJF@1239|Firmicutes,4IP1M@91061|Bacilli,1ZP90@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6848941_4	1185876.BN8_06307	1.612e-06	50.0	COG1960@1|root,COG1960@2|Bacteria,4NJ9S@976|Bacteroidetes,47Q65@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
HKD2_k127_6848941_2	796606.BMMGA3_16535	2.22e-62	217.0	COG1765@1|root,COG1765@2|Bacteria,1V7SR@1239|Firmicutes,4HK3E@91061|Bacilli,1ZR2H@1386|Bacillus	91061|Bacilli	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
HKD2_k127_6848941_0	666686.B1NLA3E_19505	2.188e-136	436.0	COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,1ZBEQ@1386|Bacillus	91061|Bacilli	Q	Multi-copper	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD2_k127_6866582_2	1403313.AXBR01000008_gene586	1.195e-156	496.0	COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,1ZBIT@1386|Bacillus	91061|Bacilli	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	yqfL	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
HKD2_k127_6866582_3	666686.B1NLA3E_16055	1.206e-104	342.0	COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,1ZB0P@1386|Bacillus	91061|Bacilli	K	CBS domain	ccpN	GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	CBS,HTH_11
HKD2_k127_6866582_0	1403313.AXBR01000008_gene588	0.0	1054.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,1ZDF3@1386|Bacillus	91061|Bacilli	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
HKD2_k127_6866582_1	1174504.AJTN02000262_gene668	2.845e-188	589.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,1ZCKP@1386|Bacillus	91061|Bacilli	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
HKD2_k127_6866824_1	665952.HMPREF1015_00404	2.446e-142	455.0	COG0707@1|root,COG0707@2|Bacteria,1UZ4A@1239|Firmicutes,4HUP6@91061|Bacilli,1ZF9P@1386|Bacillus	91061|Bacilli	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth
HKD2_k127_6866824_2	755731.Clo1100_1702	3.368e-42	156.0	COG4430@1|root,COG4430@2|Bacteria,1VA6D@1239|Firmicutes,24N9F@186801|Clostridia,36K83@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
HKD2_k127_6866824_3	1423321.AS29_18515	1.252e-21	95.0	2A0BZ@1|root,30NFF@2|Bacteria,1UARB@1239|Firmicutes,4IM41@91061|Bacilli,1ZJ3E@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6866824_4	1087481.AGFX01000013_gene2999	2.486e-08	56.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,4HADV@91061|Bacilli,26SSK@186822|Paenibacillaceae	91061|Bacilli	J	Related to alanyl-tRNA synthetase HxxxH domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD2_k127_6866824_0	1121091.AUMP01000015_gene667	3.268e-163	525.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli	91061|Bacilli	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD2_k127_6871272_1	1220589.CD32_13025	1.401e-89	302.0	COG0501@1|root,COG0501@2|Bacteria,1TQV1@1239|Firmicutes,4HDA8@91061|Bacilli	91061|Bacilli	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5,Peptidase_M48
HKD2_k127_6871272_2	1231057.AMGD01000026_gene3079	8.733e-29	119.0	COG2314@1|root,COG2314@2|Bacteria,1VGX3@1239|Firmicutes,4HPMJ@91061|Bacilli,26HQQ@186818|Planococcaceae	91061|Bacilli	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
HKD2_k127_6871272_0	1461580.CCAS010000034_gene3009	4.976e-105	349.0	COG4715@1|root,COG4715@2|Bacteria,1TSUG@1239|Firmicutes,4HGS4@91061|Bacilli,1ZC8Y@1386|Bacillus	91061|Bacilli	S	Zinc finger, swim domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
HKD2_k127_6874119_3	1033739.CAEU01000001_gene1424	6.255e-157	512.0	COG0840@1|root,COG0840@2|Bacteria,1TRIC@1239|Firmicutes,4HAEQ@91061|Bacilli,26DYH@186818|Planococcaceae	91061|Bacilli	NT	Chemoreceptor zinc-binding domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,MCPsignal,Protoglobin
HKD2_k127_6874119_8	1403313.AXBR01000027_gene5228	7.537e-59	209.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,1ZH51@1386|Bacillus	91061|Bacilli	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD2_k127_6874119_2	1211814.CAPG01000064_gene3002	2.637e-160	516.0	COG0840@1|root,COG0840@2|Bacteria,1TPI1@1239|Firmicutes,4HADY@91061|Bacilli,1ZD20@1386|Bacillus	91061|Bacilli	NT	Chemotaxis	mcpA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
HKD2_k127_6874119_6	1403313.AXBR01000027_gene5226	9.914e-85	281.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,1ZFM4@1386|Bacillus	91061|Bacilli	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD2_k127_6874119_5	1403313.AXBR01000027_gene5225	3.864e-88	294.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli,1ZFKM@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0340 family	ywlG	-	-	-	-	-	-	-	-	-	-	-	DUF436
HKD2_k127_6874119_0	1403313.AXBR01000027_gene5224	1.428e-249	773.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,1ZB9V@1386|Bacillus	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD2_k127_6874119_4	1403313.AXBR01000027_gene5223	2.961e-123	396.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,1ZASG@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
HKD2_k127_6874119_1	1403313.AXBR01000027_gene5222	5.197e-214	668.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iSB619.SA_RS11005	Epimerase_2
HKD2_k127_6874119_7	1121091.AUMP01000013_gene3283	4.107e-83	287.0	29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli	91061|Bacilli	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
HKD2_k127_6890397_8	1122915.AUGY01000012_gene3933	5.48e-38	144.0	COG1846@1|root,COG1846@2|Bacteria,1V4IP@1239|Firmicutes,4HHFS@91061|Bacilli,26WRV@186822|Paenibacillaceae	91061|Bacilli	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD2_k127_6890397_3	702450.CUW_0043	2.217e-118	395.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,3VPN4@526524|Erysipelotrichia	1239|Firmicutes	V	Polysaccharide biosynthesis C-terminal domain	mepA	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD2_k127_6890397_0	1243664.CAVL020000028_gene80	0.0	1143.0	COG0189@1|root,COG2918@1|root,COG0189@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,1ZS2T@1386|Bacillus	91061|Bacilli	H	Glutamate-cysteine ligase	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,Dala_Dala_lig_C,GARS_A,Glu_cys_ligase,RimK
HKD2_k127_6890397_10	1196324.A374_11030	2.55e-15	79.0	2EJ9Z@1|root,33D14@2|Bacteria,1VN43@1239|Firmicutes,4HRPB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6890397_5	1382305.AZUC01000046_gene385	1.3e-53	193.0	COG0454@1|root,COG0456@2|Bacteria,1VAYG@1239|Firmicutes,4HKJE@91061|Bacilli,26FPJ@186818|Planococcaceae	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
HKD2_k127_6890397_1	1132442.KB889752_gene1308	3.391e-215	672.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,4HBCM@91061|Bacilli,1ZCT1@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
HKD2_k127_6890397_7	743719.PaelaDRAFT_3327	9.979e-41	154.0	COG3278@1|root,COG3278@2|Bacteria,1VAHS@1239|Firmicutes,4HKKG@91061|Bacilli,26ZIE@186822|Paenibacillaceae	91061|Bacilli	O	COG3278 Cbb3-type cytochrome oxidase, subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	COX1
HKD2_k127_6890397_6	1294265.JCM21738_2244	3.291e-44	162.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZH5X@1386|Bacillus	91061|Bacilli	P	Sulfurtransferase	ytwF	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_6890397_9	1403313.AXBR01000010_gene1022	3.444e-25	105.0	2EJ4P@1|root,33CVX@2|Bacteria,1VMH9@1239|Firmicutes,4HSGS@91061|Bacilli,1ZIVZ@1386|Bacillus	91061|Bacilli	S	Sporulation protein Cse60	yteV	-	-	-	-	-	-	-	-	-	-	-	Spore_Cse60
HKD2_k127_6890397_4	717605.Theco_0717	7.346e-118	387.0	COG3437@1|root,COG3437@2|Bacteria,1V93U@1239|Firmicutes,4HJ0Y@91061|Bacilli,26VMB@186822|Paenibacillaceae	91061|Bacilli	KT	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD_5,PAS,PAS_9
HKD2_k127_6890397_2	634956.Geoth_1943	8.011e-154	499.0	COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	hemAT	-	-	ko:K06595	-	-	-	-	ko00000,ko02035	-	-	-	MCPsignal,Protoglobin
HKD2_k127_6890545_2	1403313.AXBR01000017_gene3795	6.124e-140	445.0	COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus	91061|Bacilli	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD2_k127_6890545_1	1174504.AJTN02000019_gene1835	0.0	1220.0	COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,1ZBMM@1386|Bacillus	91061|Bacilli	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD2_k127_6890545_6	666686.B1NLA3E_10680	1.076e-67	232.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,1ZG6W@1386|Bacillus	91061|Bacilli	S	CoA-binding protein	yneT	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
HKD2_k127_6890545_4	1403313.AXBR01000017_gene3798	3.133e-83	280.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,1ZFP9@1386|Bacillus	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HKD2_k127_6890545_3	1243664.CAVL020000025_gene1247	8.204e-110	369.0	COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,1ZBCT@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K06595	-	-	-	-	ko00000,ko02035	-	-	-	MCPsignal,Protoglobin
HKD2_k127_6890545_17	1340434.AXVA01000010_gene5484	4.127e-06	48.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6890545_15	1403313.AXBR01000017_gene3802	4.374e-12	66.0	COG3093@1|root,COG3093@2|Bacteria,1VNWW@1239|Firmicutes,4HRUI@91061|Bacilli,1ZK0J@1386|Bacillus	91061|Bacilli	K	YycC-like protein	yycC	-	-	-	-	-	-	-	-	-	-	-	YycC
HKD2_k127_6890545_10	1294265.JCM21738_5228	7.205e-31	123.0	COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,1ZHU4@1386|Bacillus	91061|Bacilli	S	Belongs to the HesB IscA family	yneR	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
HKD2_k127_6890545_9	1403313.AXBR01000017_gene3805	2.443e-48	173.0	2CICC@1|root,32S7S@2|Bacteria,1VC46@1239|Firmicutes,4HKPJ@91061|Bacilli,1ZI00@1386|Bacillus	91061|Bacilli	-	-	yneQ	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6890545_5	1403313.AXBR01000017_gene3806	3.113e-70	240.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,1ZG6C@1386|Bacillus	91061|Bacilli	S	thioesterase	yneP	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD2_k127_6890545_14	1033734.CAET01000016_gene4120	1.375e-16	81.0	2E62M@1|root,330RR@2|Bacteria,1VF8M@1239|Firmicutes,4HPWY@91061|Bacilli,1ZITR@1386|Bacillus	91061|Bacilli	S	Belongs to the Tlp family	tlp	-	-	ko:K06434	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_6890545_13	1211814.CAPG01000027_gene1195	4.611e-19	87.0	2EPWV@1|root,33HHC@2|Bacteria,1VMWH@1239|Firmicutes,4HRXR@91061|Bacilli,1ZK32@1386|Bacillus	91061|Bacilli	S	Small acid-soluble spore protein N family	sspN	-	-	ko:K06431	-	-	-	-	ko00000	-	-	-	SspN
HKD2_k127_6890545_8	1403313.AXBR01000017_gene3810	1.01e-59	211.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZFAP@1386|Bacillus	91061|Bacilli	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	stoA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD2_k127_6890545_0	1403313.AXBR01000017_gene3811	0.0	1630.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus	91061|Bacilli	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	citB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06730	Aconitase,Aconitase_C
HKD2_k127_6890545_18	1234664.AMRO01000023_gene1682	0.0001006	46.0	2EI8E@1|root,33BZS@2|Bacteria,1VNNB@1239|Firmicutes,4HS1A@91061|Bacilli,1WGZD@129337|Geobacillus	91061|Bacilli	S	asexual reproduction	sspO	-	-	ko:K06432	-	-	-	-	ko00000	-	-	-	SspO
HKD2_k127_6890545_12	1403313.AXBR01000017_gene3813	1.9e-24	105.0	2CNCH@1|root,32SGT@2|Bacteria,1VDMW@1239|Firmicutes,4HMYB@91061|Bacilli,1ZIW4@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6890545_16	666686.B1NLA3E_10600	1.72e-09	60.0	2E54C@1|root,32ZXB@2|Bacteria,1VJFQ@1239|Firmicutes,4HQN1@91061|Bacilli,1ZK01@1386|Bacillus	91061|Bacilli	S	Belongs to the SspP family	sspP	-	-	ko:K06433	-	-	-	-	ko00000	-	-	-	SspP
HKD2_k127_6890545_7	796606.BMMGA3_06775	1.118e-64	223.0	291YW@1|root,2ZPID@2|Bacteria,1V3V6@1239|Firmicutes,4HGYJ@91061|Bacilli,1ZG6E@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2621)	yneK	-	-	-	-	-	-	-	-	-	-	-	DUF2621
HKD2_k127_6890545_11	1403313.AXBR01000018_gene3534	8.448e-31	123.0	COG4846@1|root,COG4846@2|Bacteria,1V7C6@1239|Firmicutes,4HGXI@91061|Bacilli,1ZG68@1386|Bacillus	91061|Bacilli	O	COG4846 Membrane protein involved in cytochrome C biogenesis	yneJ	-	-	-	-	-	-	-	-	-	-	-	DUF1453
HKD2_k127_6915476_0	1403313.AXBR01000005_gene2037	4.172e-316	973.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,1ZBVV@1386|Bacillus	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD2_k127_6915476_3	1403313.AXBR01000005_gene2033	1.291e-62	222.0	COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1ZHWJ@1386|Bacillus	91061|Bacilli	M	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
HKD2_k127_6915476_5	1403313.AXBR01000005_gene2031	2.278e-31	127.0	2EBR1@1|root,335QY@2|Bacteria,1U5JE@1239|Firmicutes,4I5K1@91061|Bacilli,1ZJKN@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6915476_1	1403313.AXBR01000005_gene2027	5.019e-154	489.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,1ZASM@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
HKD2_k127_6915476_2	1051501.AYTL01000011_gene95	1.152e-111	361.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,4HA34@91061|Bacilli,1ZQQY@1386|Bacillus	91061|Bacilli	P	Spore Coat	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
HKD2_k127_6915476_4	1403313.AXBR01000005_gene2025	2.748e-38	144.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,4HKID@91061|Bacilli,1ZI8X@1386|Bacillus	91061|Bacilli	S	CotJB protein	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
HKD2_k127_6915476_6	279010.BL05097	1.247e-27	114.0	2E85N@1|root,332J6@2|Bacteria,1VFSE@1239|Firmicutes,4HNIY@91061|Bacilli,1ZISW@1386|Bacillus	91061|Bacilli	S	Spore coat associated protein JA (CotJA)	cotJA	-	-	ko:K06332	-	-	-	-	ko00000	-	-	-	CotJA
HKD2_k127_6963103_4	562970.Btus_1270	1.821e-05	46.0	COG1028@1|root,COG1028@2|Bacteria,1V6B9@1239|Firmicutes,4HIAJ@91061|Bacilli	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD2_k127_6963103_2	946235.CAER01000070_gene2709	1.038e-44	164.0	COG0526@1|root,COG0526@2|Bacteria,1VFUD@1239|Firmicutes,4HNQS@91061|Bacilli,23KX2@182709|Oceanobacillus	91061|Bacilli	CO	Thioredoxin	ydfQ	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD2_k127_6963103_0	696369.KI912183_gene1480	1.812e-155	507.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,2603X@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
HKD2_k127_6963103_1	1094508.Tsac_1956	5.522e-79	278.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,42F7Z@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Type II secretion system F domain	tapC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HKD2_k127_6963103_3	858215.Thexy_1158	1.506e-15	81.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,25EY6@186801|Clostridia,42GX1@68295|Thermoanaerobacterales	186801|Clostridia	NU	Pfam:N_methyl_3	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl
HKD2_k127_6963103_5	1089553.Tph_c16580	0.000541	51.0	COG4726@1|root,COG4726@2|Bacteria,1VMCQ@1239|Firmicutes,24VRD@186801|Clostridia,42HFC@68295|Thermoanaerobacterales	186801|Clostridia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_6984638_21	1403313.AXBR01000007_gene439	7.403e-28	113.0	COG1379@1|root,COG1379@2|Bacteria,1TP9P@1239|Firmicutes,4HCQ4@91061|Bacilli,1ZASI@1386|Bacillus	91061|Bacilli	L	DNA helicase	yqxK	-	-	-	-	-	-	-	-	-	-	-	PHP_C
HKD2_k127_6984638_10	1403313.AXBR01000007_gene437	8.043e-97	320.0	COG1300@1|root,COG1300@2|Bacteria,1V81P@1239|Firmicutes,4HJW8@91061|Bacilli,1ZAYC@1386|Bacillus	91061|Bacilli	S	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane	spoIIM	GO:0005575,GO:0005623,GO:0008150,GO:0010564,GO:0022603,GO:0030428,GO:0032465,GO:0032467,GO:0032954,GO:0042173,GO:0043937,GO:0044087,GO:0044089,GO:0044464,GO:0045595,GO:0045787,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051130,GO:0051302,GO:0051726,GO:0051781,GO:0065007,GO:0090068,GO:1901891,GO:1901893	-	ko:K06384	-	-	-	-	ko00000	-	-	-	SpoIIM
HKD2_k127_6984638_12	1174504.AJTN02000210_gene3303	1.749e-85	284.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,4HH78@91061|Bacilli,1ZCPG@1386|Bacillus	91061|Bacilli	P	Belongs to the Fur family	fur	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD2_k127_6984638_20	1403313.AXBR01000007_gene435	5.274e-34	132.0	2E9B4@1|root,333IZ@2|Bacteria,1VHUQ@1239|Firmicutes,4HR2C@91061|Bacilli,1ZIY4@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4227)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4227
HKD2_k127_6984638_5	1403313.AXBR01000007_gene434	6.054e-165	522.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus	91061|Bacilli	L	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_6984638_3	1174504.AJTN02000210_gene3306	6.947e-215	671.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus	91061|Bacilli	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
HKD2_k127_6984638_7	1403313.AXBR01000007_gene432	1.397e-141	452.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HKD2_k127_6984638_2	796606.BMMGA3_11090	1.005e-224	702.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus	91061|Bacilli	F	phosphorylase	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HKD2_k127_6984638_4	1403313.AXBR01000007_gene429	1.759e-202	635.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacF	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD2_k127_6984638_18	1403313.AXBR01000007_gene428	1.462e-51	184.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus	91061|Bacilli	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
HKD2_k127_6984638_15	1403313.AXBR01000007_gene427	8.004e-78	262.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,4HGYN@91061|Bacilli,1ZFKS@1386|Bacillus	91061|Bacilli	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
HKD2_k127_6984638_6	1403313.AXBR01000007_gene426	9.736e-144	458.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HC42@91061|Bacilli,1ZANZ@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD2_k127_6984638_11	1403313.AXBR01000007_gene423	2.862e-90	301.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,4HFTI@91061|Bacilli,1ZBVY@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein AA	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
HKD2_k127_6984638_16	1403313.AXBR01000007_gene422	1.668e-59	209.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,4HIN3@91061|Bacilli,1ZGZY@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein AB	spoVAB	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
HKD2_k127_6984638_14	1117379.BABA_09571	2.668e-79	269.0	29419@1|root,2ZRG2@2|Bacteria,1V3UB@1239|Firmicutes,4HI22@91061|Bacilli,1ZC8M@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein AE	spoVAEA	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAE
HKD2_k127_6984638_0	1403313.AXBR01000007_gene420	2.191e-254	791.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus	91061|Bacilli	EG	Stage V sporulation protein AF	spoVAF	-	-	ko:K06408	-	-	-	-	ko00000	-	-	-	GerA
HKD2_k127_6984638_1	1403313.AXBR01000007_gene419	1.055e-250	777.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus	91061|Bacilli	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD2_k127_6984638_8	1403313.AXBR01000007_gene418	9.222e-133	428.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,1ZD5H@1386|Bacillus	91061|Bacilli	S	Secreted protein	ypuA	-	-	-	-	-	-	-	-	-	-	-	DUF1002
HKD2_k127_6984638_19	1403313.AXBR01000007_gene417	7.124e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,1ZHDK@1386|Bacillus	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ribT	-	-	ko:K02859	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD2_k127_6984638_17	1403313.AXBR01000007_gene416	1.14e-58	209.0	COG1547@1|root,COG1547@2|Bacteria,1VBXA@1239|Firmicutes,4HMG9@91061|Bacilli,1ZH3U@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
HKD2_k127_6984638_9	1403313.AXBR01000007_gene414	1.785e-125	405.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,1ZDD6@1386|Bacillus	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD2_k127_6984638_13	1174504.AJTN02000187_gene4767	5.52e-80	271.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,1ZFNU@1386|Bacillus	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD2_k127_6986579_0	1227360.C176_00880	5.069e-215	677.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,26DED@186818|Planococcaceae	91061|Bacilli	F	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes	dbpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD2_k127_6986579_1	767817.Desgi_1104	3.946e-172	553.0	COG0348@1|root,COG1018@1|root,COG0348@2|Bacteria,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	poxF	-	1.17.1.1,1.18.1.2,1.19.1.1	ko:K00523,ko:K00528,ko:K02574,ko:K07098	ko00520,map00520	-	R03391,R03392,R10159	RC00230	ko00000,ko00001,ko01000	-	-	-	CCG,FAD_binding_6,Fer4,Fer4_8,NAD_binding_1
HKD2_k127_6986579_4	1196031.ALEG01000029_gene3691	1.209e-82	278.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD2_k127_6986579_5	1034347.CAHJ01000054_gene114	1.757e-49	184.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD2_k127_6986579_6	1305836.AXVE01000006_gene320	7.068e-44	163.0	COG0730@1|root,COG0730@2|Bacteria,1TRIE@1239|Firmicutes,4HARW@91061|Bacilli,26CUY@186818|Planococcaceae	91061|Bacilli	S	membrane transporter protein	yrkJ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD2_k127_6986579_3	1211814.CAPG01000074_gene3420	2.18e-95	314.0	COG4720@1|root,COG4720@2|Bacteria,1V1E7@1239|Firmicutes,4HGDE@91061|Bacilli,1ZBZC@1386|Bacillus	91061|Bacilli	S	ECF-type riboflavin transporter, S component	hmpT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
HKD2_k127_6986579_2	1403313.AXBR01000017_gene3681	2.245e-168	531.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,1ZDXV@1386|Bacillus	91061|Bacilli	H	Phosphomethylpyrimidine kinase	pdxK	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
HKD2_k127_6986579_7	260799.BAS2226	2.9e-13	69.0	COG1506@1|root,COG1506@2|Bacteria,1UISH@1239|Firmicutes,4HD8D@91061|Bacilli,1ZEED@1386|Bacillus	91061|Bacilli	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD2_k127_7015796_13	484770.UFO1_2883	9.518e-108	358.0	COG0600@1|root,COG0600@2|Bacteria,1UY1C@1239|Firmicutes,4H921@909932|Negativicutes	909932|Negativicutes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD2_k127_7015796_12	484770.UFO1_2882	2.467e-109	359.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4H4DE@909932|Negativicutes	909932|Negativicutes	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_7015796_24	1120973.AQXL01000091_gene1850	7.598e-14	78.0	2DTRG@1|root,33MDA@2|Bacteria,1VPDB@1239|Firmicutes,4HSKS@91061|Bacilli,278NJ@186823|Alicyclobacillaceae	91061|Bacilli	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
HKD2_k127_7015796_20	574375.BAGA_23555	5.548e-44	167.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli	91061|Bacilli	CO	COG0526, thiol-disulfide isomerase and thioredoxins	yneN	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD2_k127_7015796_17	935948.KE386494_gene670	6.009e-76	268.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,24EN3@186801|Clostridia,42GFD@68295|Thermoanaerobacterales	186801|Clostridia	P	SMART extracellular solute-binding protein family 3	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
HKD2_k127_7015796_22	1121430.JMLG01000028_gene1461	4.616e-20	96.0	COG1433@1|root,COG1433@2|Bacteria,1V88F@1239|Firmicutes,25EC4@186801|Clostridia,266T5@186807|Peptococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
HKD2_k127_7015796_9	666686.B1NLA3E_08790	4.133e-177	559.0	COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	ytmO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_7015796_1	666686.B1NLA3E_08795	7.381e-261	807.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	ytnJ	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_7015796_21	666686.B1NLA3E_08800	1.005e-34	133.0	COG0695@1|root,COG0695@2|Bacteria,1VFJ0@1239|Firmicutes,4HKXP@91061|Bacilli,1ZHVX@1386|Bacillus	91061|Bacilli	O	COG0695 Glutaredoxin and related proteins	ytnI	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
HKD2_k127_7015796_16	666686.B1NLA3E_08810	7.908e-83	277.0	COG0454@1|root,COG0456@2|Bacteria,1V6GD@1239|Firmicutes,4HJ94@91061|Bacilli,1ZR9N@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
HKD2_k127_7015796_8	666686.B1NLA3E_08815	5.934e-192	604.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus	91061|Bacilli	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	hipO2	-	-	ko:K01436,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD2_k127_7015796_11	1403313.AXBR01000002_gene4196	5.997e-136	436.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,1ZQ28@1386|Bacillus	91061|Bacilli	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD2_k127_7015796_7	1403313.AXBR01000002_gene4195	1.075e-192	606.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN_1	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
HKD2_k127_7015796_18	1034769.KB910518_gene3588	1.523e-66	233.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,26R7S@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
HKD2_k127_7015796_10	666686.B1NLA3E_08835	1.559e-153	488.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,1ZB4Z@1386|Bacillus	91061|Bacilli	M	Belongs to the nlpA lipoprotein family	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD2_k127_7015796_0	666686.B1NLA3E_08840	2.245e-274	846.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_7015796_4	1243664.CAVL020000026_gene1168	9.652e-201	631.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HBTP@91061|Bacilli,1ZATT@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_7015796_19	986075.CathTA2_0242	2.29e-44	164.0	COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4HKRK@91061|Bacilli	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD2_k127_7015796_2	1403313.AXBR01000025_gene4904	4.859e-236	749.0	COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,1ZB41@1386|Bacillus	91061|Bacilli	P	COG0025 NhaP-type Na H and K H antiporters	yvgP	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
HKD2_k127_7015796_5	1403313.AXBR01000025_gene4901	2.062e-195	619.0	COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus	91061|Bacilli	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
HKD2_k127_7015796_23	1329516.JPST01000057_gene860	1.209e-14	77.0	2EA5U@1|root,334AQ@2|Bacteria,1VJSQ@1239|Firmicutes,4HZFG@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7015796_6	1196028.ALEF01000009_gene3270	2.06e-193	612.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,4C6MB@84406|Virgibacillus	91061|Bacilli	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
HKD2_k127_7015796_3	1231057.AMGD01000005_gene2738	1.283e-213	674.0	COG0471@1|root,COG0471@2|Bacteria,1TRFV@1239|Firmicutes,4HDJC@91061|Bacilli,26ECC@186818|Planococcaceae	91061|Bacilli	P	Sodium:sulfate symporter transmembrane region	citT_1	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
HKD2_k127_7015796_14	1403313.AXBR01000025_gene4893	1.722e-101	338.0	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,1ZRKY@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
HKD2_k127_7015796_15	1403313.AXBR01000025_gene4879	9.601e-96	317.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,1ZB0K@1386|Bacillus	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD2_k127_7042295_7	1403313.AXBR01000002_gene4498	3.226e-23	100.0	2C5CS@1|root,33A0C@2|Bacteria,1VKIZ@1239|Firmicutes,4HRCC@91061|Bacilli,1ZJ2K@1386|Bacillus	91061|Bacilli	S	NETI protein	yebG	-	-	-	-	-	-	-	-	-	-	-	NETI
HKD2_k127_7042295_5	1246626.BleG1_0994	1.149e-67	235.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HKD2_k127_7042295_1	1403313.AXBR01000002_gene4496	8.895e-203	635.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,1ZB8P@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
HKD2_k127_7042295_0	1403313.AXBR01000002_gene4495	3.6e-264	815.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,1ZC7P@1386|Bacillus	91061|Bacilli	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09895	ADSL_C,Lyase_1
HKD2_k127_7042295_4	1403313.AXBR01000002_gene4494	8.644e-114	370.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,1ZAWJ@1386|Bacillus	91061|Bacilli	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HKD2_k127_7042295_6	326423.RBAM_006880	3.906e-39	147.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,1ZHUG@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
HKD2_k127_7042295_3	1403313.AXBR01000002_gene4492	3.966e-128	411.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,1ZB9C@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HKD2_k127_7042295_2	1174504.AJTN02000208_gene3384	9.388e-157	496.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD2_k127_7072867_2	663278.Ethha_1291	1.514e-10	64.0	2AJWE@1|root,31AJA@2|Bacteria,1VATY@1239|Firmicutes,24MXD@186801|Clostridia,3WQX3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7072867_0	1410674.JNKU01000010_gene1756	4.926e-88	308.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,4HE6D@91061|Bacilli,3F9SR@33958|Lactobacillaceae	91061|Bacilli	M	Bacterial capsule synthesis protein PGA_cap	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
HKD2_k127_7072867_1	1536769.P40081_11945	6.807e-78	263.0	COG1670@1|root,COG1670@2|Bacteria,1V5D0@1239|Firmicutes,4HFTD@91061|Bacilli,26WBV@186822|Paenibacillaceae	91061|Bacilli	J	GNAT family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD2_k127_7080618_7	1403313.AXBR01000008_gene617	0.0001133	44.0	2C4MB@1|root,345EE@2|Bacteria,1W0SN@1239|Firmicutes,4HP0K@91061|Bacilli,1ZJ36@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3679)	yqxA	-	-	-	-	-	-	-	-	-	-	-	DUF3679
HKD2_k127_7080618_1	1403313.AXBR01000008_gene618	1.022e-166	533.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus	91061|Bacilli	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
HKD2_k127_7080618_6	1385514.N782_03495	1.525e-07	54.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7080618_0	1403313.AXBR01000008_gene619	3.711e-195	613.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus	91061|Bacilli	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
HKD2_k127_7080618_4	1403313.AXBR01000008_gene620	5.38e-32	126.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,1ZI3X@1386|Bacillus	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HKD2_k127_7080618_2	1403313.AXBR01000008_gene621	8.006e-165	524.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD2_k127_7080618_3	1403313.AXBR01000008_gene623	2.135e-161	519.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HKD2_k127_7080640_13	1403313.AXBR01000018_gene3534	4.218e-20	91.0	COG4846@1|root,COG4846@2|Bacteria,1V7C6@1239|Firmicutes,4HGXI@91061|Bacilli,1ZG68@1386|Bacillus	91061|Bacilli	O	COG4846 Membrane protein involved in cytochrome C biogenesis	yneJ	-	-	-	-	-	-	-	-	-	-	-	DUF1453
HKD2_k127_7080640_7	1034347.CAHJ01000010_gene1953	2.5e-60	209.0	COG2201@1|root,COG2201@2|Bacteria,1V71X@1239|Firmicutes,4HITX@91061|Bacilli,1ZHDB@1386|Bacillus	91061|Bacilli	T	cheY-homologous receiver domain	yneI	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
HKD2_k127_7080640_4	1117379.BABA_04299	2.763e-111	363.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus	91061|Bacilli	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
HKD2_k127_7080640_9	1340434.AXVA01000003_gene1955	8.681e-31	122.0	COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,1ZHYQ@1386|Bacillus	91061|Bacilli	S	UPF0154 protein	yneF	-	-	ko:K09976	-	-	-	-	ko00000	-	-	-	UPF0154
HKD2_k127_7080640_8	1403313.AXBR01000018_gene3544	2.707e-56	199.0	2EUDS@1|root,33MW4@2|Bacteria,1VHIA@1239|Firmicutes,4HSFG@91061|Bacilli,1ZEP8@1386|Bacillus	91061|Bacilli	S	Sporulation inhibitor of replication protein sirA	yneE	-	-	-	-	-	-	-	-	-	-	-	SirA
HKD2_k127_7080640_0	1403313.AXBR01000018_gene3545	0.0	1193.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,1ZBQ6@1386|Bacillus	91061|Bacilli	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
HKD2_k127_7080640_11	1403313.AXBR01000018_gene3546	2.24e-25	110.0	COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,1ZIU8@1386|Bacillus	91061|Bacilli	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
HKD2_k127_7080640_5	1403313.AXBR01000018_gene3547	2.459e-101	334.0	COG1961@1|root,COG1961@2|Bacteria,1TR74@1239|Firmicutes,4HBJI@91061|Bacilli,1ZCET@1386|Bacillus	91061|Bacilli	L	resolvase	yneB	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	-	-	-	-	-	-	-	-	-	Resolvase
HKD2_k127_7080640_10	1403313.AXBR01000018_gene3548	9.574e-31	124.0	COG1388@1|root,COG1388@2|Bacteria,1VK5T@1239|Firmicutes,4HRE2@91061|Bacilli,1ZJ7X@1386|Bacillus	91061|Bacilli	M	Cell division suppressor protein YneA	yneA	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	-	-	-	-	-	-	-	-	-	-	LysM
HKD2_k127_7080640_3	1403313.AXBR01000018_gene3549	8.682e-114	370.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,1ZBMU@1386|Bacillus	91061|Bacilli	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HKD2_k127_7080640_14	1444310.JANV01000162_gene1157	1.18e-17	84.0	2ERH2@1|root,33J2J@2|Bacteria,1VP49@1239|Firmicutes,4HSDF@91061|Bacilli,1ZJEW@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
HKD2_k127_7080640_2	1340434.AXVA01000003_gene1985	2.091e-254	792.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli	91061|Bacilli	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
HKD2_k127_7080640_15	358681.BBR47_33420	9.996e-11	62.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HEI7@91061|Bacilli,26VNW@186822|Paenibacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HKD2_k127_7080640_1	1211814.CAPG01000037_gene2002	1.427e-274	847.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,1ZBIQ@1386|Bacillus	91061|Bacilli	E	glutamine synthetase	glnA	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD2_k127_7080640_6	1403313.AXBR01000021_gene2978	2.852e-63	219.0	COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,1ZH1F@1386|Bacillus	91061|Bacilli	K	transcriptional	glnR	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141	-	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	MerR_1
HKD2_k127_7080640_12	796606.BMMGA3_06575	8.714e-23	97.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus	91061|Bacilli	P	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
HKD2_k127_7093070_16	1385514.N782_03495	5.403e-05	47.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7093070_10	1403313.AXBR01000008_gene738	1.453e-45	169.0	2E8Q1@1|root,33314@2|Bacteria,1VFPE@1239|Firmicutes,4HPJ2@91061|Bacilli,1ZHSS@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3792)	yrzE	-	-	-	-	-	-	-	-	-	-	-	DUF3792
HKD2_k127_7093070_12	1403313.AXBR01000008_gene739	7.154e-34	132.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,1ZHST@1386|Bacillus	91061|Bacilli	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HKD2_k127_7093070_0	1403313.AXBR01000008_gene740	6.508e-249	769.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,1ZBFJ@1386|Bacillus	91061|Bacilli	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HKD2_k127_7093070_3	1403313.AXBR01000008_gene741	2.116e-189	595.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,1ZB71@1386|Bacillus	91061|Bacilli	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD2_k127_7093070_13	1403313.AXBR01000008_gene742	2.902e-22	97.0	2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,4HPC6@91061|Bacilli,1ZJ6M@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2905)	yrzS	-	-	-	-	-	-	-	-	-	-	-	DUF2905
HKD2_k127_7093070_2	1403313.AXBR01000008_gene743	3.067e-192	602.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,1ZC5A@1386|Bacillus	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HKD2_k127_7093070_5	1403313.AXBR01000008_gene744	1.562e-103	339.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,1ZBJT@1386|Bacillus	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HKD2_k127_7093070_7	997296.PB1_10097	3.396e-80	276.0	29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus	91061|Bacilli	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
HKD2_k127_7093070_9	1403313.AXBR01000008_gene745	1.986e-48	178.0	2DGQY@1|root,32U7R@2|Bacteria,1V83A@1239|Firmicutes,4HKRI@91061|Bacilli,1ZH9Y@1386|Bacillus	91061|Bacilli	S	BofC C-terminal domain	bofC	-	-	ko:K06318	-	-	-	-	ko00000	-	-	-	BOFC_N,BofC_C
HKD2_k127_7093070_6	1403313.AXBR01000008_gene747	4.791e-93	317.0	COG0510@1|root,COG0510@2|Bacteria,1VB8C@1239|Firmicutes,4HNC9@91061|Bacilli,1ZAQ0@1386|Bacillus	91061|Bacilli	M	choline kinase involved in LPS biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	APH
HKD2_k127_7093070_8	1211814.CAPG01000048_gene2532	6.519e-56	217.0	COG1388@1|root,COG1716@1|root,COG1388@2|Bacteria,COG1716@2|Bacteria,1VETU@1239|Firmicutes,4HP2D@91061|Bacilli,1ZD0H@1386|Bacillus	91061|Bacilli	M	spore coat assembly protein SafA	safA	GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117	-	ko:K06370	-	-	-	-	ko00000	-	-	-	LysM
HKD2_k127_7093070_1	1403313.AXBR01000009_gene752	1.444e-196	616.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HKD2_k127_7093070_4	1403313.AXBR01000009_gene753	6.439e-139	445.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,1ZBVN@1386|Bacillus	91061|Bacilli	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD2_k127_7093070_14	1033734.CAET01000016_gene4041	1.38e-11	67.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus	91061|Bacilli	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD2_k127_7112374_1	1403313.AXBR01000005_gene2018	8.211e-224	706.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_9
HKD2_k127_7112374_12	1403313.AXBR01000005_gene2012	9.355e-61	213.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,4ISB2@91061|Bacilli,1ZS4F@1386|Bacillus	91061|Bacilli	S	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD2_k127_7112374_13	1403313.AXBR01000005_gene2007	9.873e-52	184.0	COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,1ZH23@1386|Bacillus	91061|Bacilli	K	transcriptional	yodB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	HxlR
HKD2_k127_7112374_6	1403313.AXBR01000005_gene2004	4.868e-160	508.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,1ZBK6@1386|Bacillus	91061|Bacilli	P	Mg2 transporter protein CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD2_k127_7112374_18	1131730.BAVI_15631	3.114e-31	124.0	2E5FN@1|root,3307C@2|Bacteria,1VH91@1239|Firmicutes,4HP9B@91061|Bacilli,1ZJ6Z@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0180 family	ykuS	-	-	-	-	-	-	-	-	-	-	-	UPF0180
HKD2_k127_7112374_19	1174504.AJTN02000195_gene4203	1.381e-12	69.0	COG1764@1|root,COG1764@2|Bacteria,1V41Y@1239|Firmicutes,4HH9W@91061|Bacilli,1ZFXM@1386|Bacillus	91061|Bacilli	O	redox protein, regulator of disulfide bond formation	ymaD	-	-	-	-	-	-	-	-	-	-	-	OsmC
HKD2_k127_7112374_8	1403313.AXBR01000005_gene1991	4.302e-84	284.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,1ZB1C@1386|Bacillus	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	ywrF	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD2_k127_7112374_15	1403313.AXBR01000005_gene1980	1.062e-40	152.0	COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli,1ZHTP@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
HKD2_k127_7112374_14	1211814.CAPG01000077_gene3645	6.369e-42	158.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZI0X@1386|Bacillus	91061|Bacilli	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_7112374_0	1403313.AXBR01000005_gene1979	5.34e-244	761.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	ywnE	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HKD2_k127_7112374_9	1403313.AXBR01000005_gene1902	1.133e-80	275.0	2DJ6D@1|root,304V1@2|Bacteria,1TX8K@1239|Firmicutes,4I65H@91061|Bacilli,1ZDYT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7112374_21	1408303.JNJJ01000020_gene4060	6.324e-06	55.0	COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,1ZGB4@1386|Bacillus	91061|Bacilli	K	Competence transcription factor	comK	-	-	ko:K02250	ko02024,map02024	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	ComK
HKD2_k127_7112374_5	1403313.AXBR01000014_gene2235	3.841e-161	517.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,4HBYI@91061|Bacilli,1ZQYP@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase group 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_7112374_4	1403313.AXBR01000014_gene2236	8.03e-193	610.0	COG0438@1|root,COG0438@2|Bacteria,1TT92@1239|Firmicutes,4HCQ5@91061|Bacilli,1ZQYM@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_7112374_2	198094.BA_5512	2.795e-199	628.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1ZC93@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capO	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD2_k127_7112374_10	1403313.AXBR01000005_gene1878	7.148e-78	265.0	COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli,1ZB2X@1386|Bacillus	91061|Bacilli	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	XK27_06885	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD2_k127_7112374_7	1403313.AXBR01000005_gene1876	1.108e-137	445.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,1ZANH@1386|Bacillus	91061|Bacilli	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
HKD2_k127_7112374_11	1403313.AXBR01000005_gene1874	5.258e-76	257.0	COG0590@1|root,COG0590@2|Bacteria,1V7G0@1239|Firmicutes,4HJIH@91061|Bacilli,1ZEIN@1386|Bacillus	91061|Bacilli	FJ	COG0590 Cytosine adenosine deaminases	guaD	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
HKD2_k127_7112374_16	1403313.AXBR01000005_gene1864	7.883e-40	152.0	2B0T9@1|root,31T5P@2|Bacteria,1V9AV@1239|Firmicutes,4HM11@91061|Bacilli,1ZI0C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
HKD2_k127_7112374_17	1403313.AXBR01000005_gene1861	8.512e-39	149.0	COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,1ZI9H@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1694)	XK27_05190	-	-	-	-	-	-	-	-	-	-	-	DUF1694
HKD2_k127_7112374_3	1403313.AXBR01000005_gene1858	3.549e-196	615.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,1ZBFM@1386|Bacillus	91061|Bacilli	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU38550	Aminotran_4
HKD2_k127_7113101_0	1169144.KB910953_gene3124	2.705e-86	287.0	COG1132@1|root,COG1132@2|Bacteria,1TQAN@1239|Firmicutes,4HBES@91061|Bacilli,1ZB30@1386|Bacillus	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	hetA	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
HKD2_k127_7113101_2	545693.BMQ_1655	3.584e-58	208.0	COG1434@1|root,COG1434@2|Bacteria,1VB45@1239|Firmicutes,4HMVM@91061|Bacilli,1ZI4Z@1386|Bacillus	91061|Bacilli	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD2_k127_7113101_3	1169144.KB910980_gene1532	9.946e-48	179.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,1ZBJ4@1386|Bacillus	91061|Bacilli	M	biosynthesis protein	ywqC	-	-	-	-	-	-	-	-	-	-	-	Wzz
HKD2_k127_7113101_1	796606.BMMGA3_15555	9.59e-69	240.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,1ZB83@1386|Bacillus	91061|Bacilli	D	COG0489 ATPases involved in chromosome partitioning	ywqD	-	2.7.10.2	ko:K00903	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,ParA
HKD2_k127_7118226_0	1033737.CAEV01000062_gene2988	7.562e-75	257.0	COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,24FU4@186801|Clostridia,36F1N@31979|Clostridiaceae	186801|Clostridia	S	PFAM SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
HKD2_k127_7118226_1	1033734.CAET01000006_gene3874	4.621e-29	118.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZG2X@1386|Bacillus	91061|Bacilli	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
HKD2_k127_7146706_5	1196324.A374_13940	5.489e-26	107.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli	91061|Bacilli	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	nupC	-	-	ko:K11535	-	-	-	-	ko00000,ko02000	2.A.41.1	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
HKD2_k127_7146706_1	1131730.BAVI_20531	1.399e-105	346.0	29DTM@1|root,32UXJ@2|Bacteria,1VEA3@1239|Firmicutes,4HN2P@91061|Bacilli,1ZFX9@1386|Bacillus	91061|Bacilli	S	AmiS/UreI family transporter	-	-	-	ko:K22112	-	-	-	-	ko00000,ko02000	1.A.29.1.1,1.A.29.1.2,1.A.29.1.6	-	-	AmiS_UreI
HKD2_k127_7146706_4	1307436.PBF_18094	2.316e-49	180.0	29TDV@1|root,30EM1@2|Bacteria,1UCQ1@1239|Firmicutes,4IP69@91061|Bacilli,1ZPFX@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7146706_3	1132442.KB889752_gene1980	4.295e-63	217.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli,1ZH56@1386|Bacillus	91061|Bacilli	P	Alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
HKD2_k127_7146706_0	1131730.BAVI_11679	5.216e-118	383.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,1ZCXP@1386|Bacillus	91061|Bacilli	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	ctfA	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_7146706_6	1131730.BAVI_11674	3.887e-14	72.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus	91061|Bacilli	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	-	-	2.8.3.8,2.8.3.9	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_7150724_12	1403313.AXBR01000008_gene505	1.044e-23	102.0	2E7KE@1|root,3322G@2|Bacteria,1VG6C@1239|Firmicutes,4HNMG@91061|Bacilli,1ZH76@1386|Bacillus	91061|Bacilli	S	Stage III sporulation protein AF (Spore_III_AF)	spoIIIAF	-	-	ko:K06395	-	-	-	-	ko00000	-	-	-	Spore_III_AF
HKD2_k127_7150724_0	1403313.AXBR01000008_gene506	9.061e-199	625.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,4H9UX@91061|Bacilli,1ZCFI@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
HKD2_k127_7150724_9	1499680.CCFE01000018_gene1627	2.164e-56	199.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,4HIIH@91061|Bacilli,1ZGYV@1386|Bacillus	91061|Bacilli	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HKD2_k127_7150724_15	1384049.CD29_11870	0.0003851	45.0	2E58S@1|root,33016@2|Bacteria,1VFG3@1239|Firmicutes,4HPI7@91061|Bacilli,3IYMT@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HKD2_k127_7150724_8	634956.Geoth_1271	2.221e-61	215.0	2CEWW@1|root,32S0Q@2|Bacteria,1VAEG@1239|Firmicutes,4HGSK@91061|Bacilli,1WHTC@129337|Geobacillus	91061|Bacilli	S	Stage III sporulation protein AB (spore_III_AB)	spoIIIAB	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
HKD2_k127_7150724_4	1403313.AXBR01000008_gene510	6.44e-139	447.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	AAA,T2SSE
HKD2_k127_7150724_6	1403313.AXBR01000008_gene511	1.15e-99	327.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,1ZAT9@1386|Bacillus	91061|Bacilli	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD2_k127_7150724_1	1403313.AXBR01000008_gene512	5.448e-188	594.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	yqhT	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HKD2_k127_7150724_7	1403313.AXBR01000008_gene513	1.953e-68	234.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,4HJ2V@91061|Bacilli,1ZG8H@1386|Bacillus	91061|Bacilli	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
HKD2_k127_7150724_10	1403313.AXBR01000008_gene514	5.97e-53	191.0	29VNZ@1|root,30H6A@2|Bacteria,1V5PG@1239|Firmicutes,4HJV5@91061|Bacilli,1ZBD8@1386|Bacillus	91061|Bacilli	S	Conserved membrane protein YqhR	yqhR	-	-	-	-	-	-	-	-	-	-	-	YqhR
HKD2_k127_7150724_3	1403313.AXBR01000008_gene515	9.791e-163	516.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H9KN@91061|Bacilli,1ZBXJ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1385)	yqhQ	-	-	-	-	-	-	-	-	-	-	-	DUF1385
HKD2_k127_7150724_11	1403313.AXBR01000008_gene516	3.021e-32	130.0	2BYG1@1|root,33M6N@2|Bacteria,1U3TH@1239|Firmicutes,4IC1U@91061|Bacilli,1ZIYH@1386|Bacillus	91061|Bacilli	-	-	yqhP	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7150724_14	1385514.N782_03495	0.0003443	44.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7150724_5	1403313.AXBR01000008_gene517	1.494e-136	439.0	COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes,4HB8J@91061|Bacilli,1ZC13@1386|Bacillus	91061|Bacilli	S	esterase of the alpha-beta hydrolase superfamily	yqhO	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HKD2_k127_7150724_2	1403313.AXBR01000008_gene520	7.219e-168	529.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus	91061|Bacilli	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
HKD2_k127_717421_7	1403313.AXBR01000009_gene892	3.499e-32	125.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,1ZBGS@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_717421_1	1403313.AXBR01000009_gene891	5.009e-227	717.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus	91061|Bacilli	T	Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
HKD2_k127_717421_0	1403313.AXBR01000009_gene888	0.0	1426.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
HKD2_k127_717421_4	1403313.AXBR01000009_gene887	5.111e-150	478.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,1ZCC9@1386|Bacillus	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HKD2_k127_717421_8	1340434.AXVA01000010_gene5484	5.871e-06	52.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_717421_5	1403313.AXBR01000009_gene886	1.52e-86	292.0	COG1971@1|root,COG1971@2|Bacteria,1V4BC@1239|Firmicutes,4HH29@91061|Bacilli,1ZCPR@1386|Bacillus	91061|Bacilli	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD2_k127_717421_6	1403313.AXBR01000009_gene885	4.885e-82	277.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,1ZFSI@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
HKD2_k127_717421_3	1243664.CAVL020000038_gene832	2.092e-186	593.0	COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HDUQ@91061|Bacilli,1ZC8H@1386|Bacillus	91061|Bacilli	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	ko:K05548	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4,Sugar_tr
HKD2_k127_717421_2	1403313.AXBR01000009_gene884	1.046e-190	599.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapB	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD2_k127_7191600_9	332101.JIBU02000013_gene1275	5.275e-08	54.0	COG0107@1|root,COG0107@2|Bacteria,1TY4A@1239|Firmicutes,24FPW@186801|Clostridia,36RT0@31979|Clostridiaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	-	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD2_k127_7191600_1	332101.JIBU02000013_gene1278	1.92e-123	401.0	COG0500@1|root,COG2226@2|Bacteria,1VRSU@1239|Firmicutes,251EV@186801|Clostridia,36RR4@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7191600_8	1132442.KB889752_gene2936	1.223e-19	90.0	2C8CJ@1|root,2ZJ25@2|Bacteria,1W3J4@1239|Firmicutes,4I271@91061|Bacilli,1ZKIW@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7191600_0	1034347.CAHJ01000029_gene3626	2.592e-151	507.0	COG1196@1|root,COG1196@2|Bacteria,1UYPN@1239|Firmicutes,4IRMM@91061|Bacilli,1ZRVM@1386|Bacillus	91061|Bacilli	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7191600_7	1174504.AJTN02000254_gene2288	6.293e-32	126.0	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,4HQ79@91061|Bacilli,1ZI6Y@1386|Bacillus	91061|Bacilli	N	FlhB HrpN YscU SpaS Family	-	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
HKD2_k127_7191600_4	1174504.AJTN02000254_gene2287	3.051e-50	182.0	COG1516@1|root,COG1516@2|Bacteria,1VD1D@1239|Firmicutes,4HMXD@91061|Bacilli,1ZHE1@1386|Bacillus	91061|Bacilli	N	flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
HKD2_k127_7191600_2	536233.CLO_3881	3.164e-109	371.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,36ED6@31979|Clostridiaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
HKD2_k127_7191600_3	1174504.AJTN02000254_gene2285	8.09e-61	212.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,4HP8D@91061|Bacilli,1ZFYU@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yaaR	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
HKD2_k127_7191600_6	1403313.AXBR01000013_gene1282	3.538e-35	138.0	COG1334@1|root,COG1334@2|Bacteria,1VFRY@1239|Firmicutes,4HNSH@91061|Bacilli,1ZIZC@1386|Bacillus	91061|Bacilli	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
HKD2_k127_7191600_5	1403313.AXBR01000013_gene1283	4.554e-50	182.0	COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,4H9TN@91061|Bacilli,1ZCIG@1386|Bacillus	91061|Bacilli	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
HKD2_k127_7203937_26	1403313.AXBR01000024_gene4664	2.868e-34	132.0	COG2427@1|root,32RCT@2|Bacteria,1V7FZ@1239|Firmicutes,4HK07@91061|Bacilli,1ZR46@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1641)	yjlC	-	-	-	-	-	-	-	-	-	-	-	DUF1641
HKD2_k127_7203937_5	1403313.AXBR01000021_gene2993	5.431e-213	665.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	yjlD	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iYO844.BSU12290	Pyr_redox_2
HKD2_k127_7203937_7	1403313.AXBR01000013_gene1363	3.466e-172	545.0	COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus	91061|Bacilli	I	fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD2_k127_7203937_9	1196323.ALKF01000172_gene127	3.593e-143	463.0	COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,26QHQ@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	desK	GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
HKD2_k127_7203937_11	1134413.ANNK01000144_gene3837	2.146e-104	341.0	COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,1ZC1V@1386|Bacillus	91061|Bacilli	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	desR	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
HKD2_k127_7203937_10	471223.GWCH70_1213	2.723e-121	402.0	COG3420@1|root,COG3420@2|Bacteria,1UN63@1239|Firmicutes,4HAZN@91061|Bacilli,1WFE8@129337|Geobacillus	91061|Bacilli	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
HKD2_k127_7203937_21	634956.Geoth_1640	6.925e-57	203.0	COG4314@1|root,COG4314@2|Bacteria,1V86E@1239|Firmicutes,4HJXZ@91061|Bacilli,1WGI5@129337|Geobacillus	91061|Bacilli	C	NosL	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD2_k127_7203937_30	1294265.JCM21738_1787	6.558e-06	49.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD2_k127_7203937_32	1385514.N782_03495	0.0002699	44.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7203937_14	471223.GWCH70_1215	4.1e-97	325.0	COG1277@1|root,COG1277@2|Bacteria,1UZYB@1239|Firmicutes,4HEYC@91061|Bacilli,1WEYF@129337|Geobacillus	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
HKD2_k127_7203937_16	1169144.KB910933_gene4199	9.096e-89	298.0	COG1131@1|root,COG1131@2|Bacteria,1UZ5J@1239|Firmicutes,4HJEF@91061|Bacilli,1ZG0S@1386|Bacillus	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Rad17
HKD2_k127_7203937_13	333138.LQ50_05220	7.308e-103	338.0	COG2227@1|root,COG2227@2|Bacteria,1UYCM@1239|Firmicutes,4HDSS@91061|Bacilli,1ZETT@1386|Bacillus	91061|Bacilli	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
HKD2_k127_7203937_28	1403313.AXBR01000013_gene1380	2.526e-21	96.0	2B5J4@1|root,31YE2@2|Bacteria,1UAIN@1239|Firmicutes,4IKX4@91061|Bacilli,1ZI5X@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1450
HKD2_k127_7203937_1	1403313.AXBR01000013_gene1386	0.0	1005.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus	91061|Bacilli	M	Belongs to the LTA synthase family	yfnI	GO:0005575,GO:0005576	2.7.8.20	ko:K19005	ko00561,ko01100,map00561,map01100	-	R05081,R10849	RC00017	ko00000,ko00001,ko01000	-	-	-	Sulfatase
HKD2_k127_7203937_15	1403313.AXBR01000013_gene1387	1.732e-89	299.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,4HGQE@91061|Bacilli,1ZB81@1386|Bacillus	91061|Bacilli	H	Methyltransferase	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
HKD2_k127_7203937_12	1174504.AJTN02000001_gene2834	2.257e-103	342.0	COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,1ZCJG@1386|Bacillus	91061|Bacilli	V	ATPases associated with a variety of cellular activities	hrtA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_7203937_8	1117379.BABA_00625	8.053e-153	490.0	COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,1ZCYR@1386|Bacillus	91061|Bacilli	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD2_k127_7203937_17	1347369.CCAD010000094_gene2231	8.848e-76	258.0	COG1695@1|root,COG1695@2|Bacteria,1V7AI@1239|Firmicutes,4HISS@91061|Bacilli,1ZFMT@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
HKD2_k127_7203937_25	1403313.AXBR01000013_gene1391	3.617e-35	140.0	2DZ9Y@1|root,32V70@2|Bacteria,1VA6H@1239|Firmicutes,4HKSG@91061|Bacilli,1ZHSJ@1386|Bacillus	91061|Bacilli	S	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)	yhcN	-	-	-	-	-	-	-	-	-	-	-	Spore_YhcN_YlaJ
HKD2_k127_7203937_6	1403313.AXBR01000013_gene1402	7.663e-206	644.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HKD2_k127_7203937_24	1403313.AXBR01000013_gene1403	2.165e-40	152.0	COG5577@1|root,COG5577@2|Bacteria,1V96G@1239|Firmicutes,4HK73@91061|Bacilli,1ZHVT@1386|Bacillus	91061|Bacilli	M	Coat F domain	yusN	-	-	-	-	-	-	-	-	-	-	-	Coat_F
HKD2_k127_7203937_27	1403313.AXBR01000013_gene1404	2.707e-29	119.0	2E37R@1|root,32Y7E@2|Bacteria,1VEJ6@1239|Firmicutes,4HNWR@91061|Bacilli,1ZIXG@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7203937_0	1403313.AXBR01000013_gene1407	0.0	1250.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
HKD2_k127_7203937_4	1403313.AXBR01000013_gene1408	2.906e-219	683.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_7203937_2	1174504.AJTN02000230_gene1317	6.578e-316	974.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,1ZBUU@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	fadE	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_7203937_20	1403313.AXBR01000013_gene1411	4.864e-59	205.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,1ZH0I@1386|Bacillus	91061|Bacilli	P	Belongs to the ArsC family	yusI	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
HKD2_k127_7203937_18	935836.JAEL01000113_gene1399	2.969e-66	227.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,1ZGG0@1386|Bacillus	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
HKD2_k127_7203937_22	1403313.AXBR01000013_gene1413	7.626e-44	164.0	COG1658@1|root,COG1658@2|Bacteria,1VBXW@1239|Firmicutes,4HKN4@91061|Bacilli,1ZH1R@1386|Bacillus	91061|Bacilli	L	COG1658 Small primase-like proteins (Toprim domain)	yusF	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	ko:K07476	-	-	-	-	ko00000	-	-	-	Toprim,Toprim_2
HKD2_k127_7203937_23	1403313.AXBR01000013_gene1414	1.603e-40	151.0	COG0526@1|root,COG0526@2|Bacteria,1VEVR@1239|Firmicutes,4HNM9@91061|Bacilli,1ZIVX@1386|Bacillus	91061|Bacilli	CO	Thioredoxin	yusE	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD2_k127_7203937_3	1174504.AJTN02000230_gene1324	7.358e-235	732.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli,1ZS2F@1386|Bacillus	91061|Bacilli	E	O-acetylhomoserine	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD2_k127_7203937_19	1403313.AXBR01000013_gene1416	2.375e-60	211.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	iYO844.BSU32750	ABC_tran,NIL
HKD2_k127_7219360_2	1403313.AXBR01000026_gene5196	3.849e-52	188.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,4HCE3@91061|Bacilli,1ZBNU@1386|Bacillus	91061|Bacilli	D	Stage II sporulation protein D	spoIID	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
HKD2_k127_7219360_0	1403313.AXBR01000026_gene5197	2.479e-245	761.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZB89@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD2_k127_7219360_1	1403313.AXBR01000026_gene5198	4.632e-73	254.0	2DSIK@1|root,33GA6@2|Bacteria,1VN6K@1239|Firmicutes,4HSJR@91061|Bacilli,1ZHV5@1386|Bacillus	91061|Bacilli	S	TATA-box binding	ywmB	-	-	-	-	-	-	-	-	-	-	-	DUF1779
HKD2_k127_7219360_3	1403313.AXBR01000026_gene5199	4.073e-31	123.0	COG4836@1|root,COG4836@2|Bacteria,1VK5C@1239|Firmicutes,4HR8D@91061|Bacilli,1ZJ1E@1386|Bacillus	91061|Bacilli	S	membrane	ywzB	-	-	-	-	-	-	-	-	-	-	-	DUF1146
HKD2_k127_7236030_1	935837.JAEK01000041_gene3782	1.596e-130	423.0	COG1409@1|root,COG1409@2|Bacteria,1VMBT@1239|Firmicutes,4HUFU@91061|Bacilli	91061|Bacilli	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD2_k127_7236030_2	1403313.AXBR01000007_gene440	2.204e-86	288.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,1ZFIW@1386|Bacillus	91061|Bacilli	L	Belongs to the Nudix hydrolase family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
HKD2_k127_7236030_0	1227360.C176_11284	2.051e-158	505.0	COG1379@1|root,COG1379@2|Bacteria,1TP9P@1239|Firmicutes,4HCQ4@91061|Bacilli,26EJY@186818|Planococcaceae	91061|Bacilli	L	DNA helicase	yqxK	-	-	-	-	-	-	-	-	-	-	-	PHP_C
HKD2_k127_7245372_1	871968.DESME_05385	3.358e-128	412.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24A9J@186801|Clostridia,2614Z@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD2_k127_7245372_0	198467.NP92_00445	0.0	1169.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,21VC1@150247|Anoxybacillus	91061|Bacilli	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	iYO844.BSU30940	Phosphorylase
HKD2_k127_7245372_3	861530.ALOZ01000027_gene420	1.587e-10	63.0	2EIAV@1|root,33C29@2|Bacteria,1VMAE@1239|Firmicutes,4HRG9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7245372_2	1403313.AXBR01000014_gene2203	1.685e-17	82.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7248047_10	380749.HY04AAS1_1579	2.747e-10	61.0	COG0615@1|root,COG0615@2|Bacteria,2G3YJ@200783|Aquificae	200783|Aquificae	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
HKD2_k127_7248047_9	1403313.AXBR01000008_gene617	8.273e-43	158.0	2C4MB@1|root,345EE@2|Bacteria,1W0SN@1239|Firmicutes,4HP0K@91061|Bacilli,1ZJ36@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3679)	yqxA	-	-	-	-	-	-	-	-	-	-	-	DUF3679
HKD2_k127_7248047_0	1403313.AXBR01000008_gene616	0.0	1133.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
HKD2_k127_7248047_4	1403313.AXBR01000008_gene615	3.986e-178	564.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,1ZC7V@1386|Bacillus	91061|Bacilli	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD2_k127_7248047_6	1403313.AXBR01000008_gene614	1.147e-169	537.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,1ZBQV@1386|Bacillus	91061|Bacilli	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
HKD2_k127_7248047_8	1403313.AXBR01000008_gene613	8.544e-78	265.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,1ZGCW@1386|Bacillus	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HKD2_k127_7248047_1	1403313.AXBR01000008_gene612	0.0	1091.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus	91061|Bacilli	O	Heat shock 70 kDa protein	dnaK	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD2_k127_7248047_12	1385514.N782_03495	1.897e-07	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7248047_11	1294265.JCM21738_1838	6.228e-08	54.0	COG4768@1|root,COG4768@2|Bacteria,1UBBB@1239|Firmicutes,4IMQ8@91061|Bacilli,1ZKKT@1386|Bacillus	91061|Bacilli	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
HKD2_k127_7248047_3	1499680.CCFE01000018_gene1537	5.608e-207	647.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1ZC0R@1386|Bacillus	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD2_k127_7248047_5	1174504.AJTN02000155_gene1991	1.397e-173	547.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,1ZB7J@1386|Bacillus	91061|Bacilli	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HKD2_k127_7248047_7	1403313.AXBR01000008_gene608	4.762e-118	383.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HKD2_k127_7248047_2	1174504.AJTN02000155_gene1989	4.889e-228	709.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,1ZB8Q@1386|Bacillus	91061|Bacilli	J	ribosomal protein S12 methylthiotransferase	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD2_k127_7255361_9	315749.Bcer98_0294	1.22e-06	57.0	2EH82@1|root,33AZX@2|Bacteria	2|Bacteria	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
HKD2_k127_7255361_0	1403313.AXBR01000007_gene275	2.027e-159	505.0	COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus	91061|Bacilli	L	5'3' exonuclease	ypcP	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
HKD2_k127_7255361_5	1403313.AXBR01000007_gene274	9.748e-35	134.0	2E93T@1|root,333CR@2|Bacteria,1VFQW@1239|Firmicutes,4HPTY@91061|Bacilli,1ZISY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7255361_6	1403313.AXBR01000007_gene273	6.259e-19	88.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,1ZC5Q@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_7255361_8	1403313.AXBR01000007_gene273	4.122e-10	62.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,1ZC5Q@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_7255361_4	1403313.AXBR01000007_gene272	5.85e-58	204.0	COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,1ZH35@1386|Bacillus	91061|Bacilli	L	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H,RVT_3
HKD2_k127_7255361_2	1174504.AJTN02000196_gene3406	1.125e-92	309.0	COG0328@1|root,COG0328@2|Bacteria,1V3K2@1239|Firmicutes,4HE8H@91061|Bacilli,1ZDMZ@1386|Bacillus	91061|Bacilli	L	COG0328 Ribonuclease HI	ypeP	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
HKD2_k127_7255361_7	326423.RBAM_020100	5.406e-17	82.0	2E6UK@1|root,331EA@2|Bacteria,1VF2M@1239|Firmicutes,4HPQ1@91061|Bacilli,1ZKC4@1386|Bacillus	91061|Bacilli	S	Zinc-finger	ypeQ	-	-	-	-	-	-	-	-	-	-	-	zf-C2HCIx2C
HKD2_k127_7255361_1	1174504.AJTN02000196_gene3408	4.09e-110	366.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HF2G@91061|Bacilli,1ZE39@1386|Bacillus	91061|Bacilli	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
HKD2_k127_7255361_3	1403313.AXBR01000007_gene269	1.643e-74	253.0	COG1959@1|root,COG1959@2|Bacteria,1V4G2@1239|Firmicutes,4HHBH@91061|Bacilli,1ZH5D@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
HKD2_k127_7255664_8	1131730.BAVI_25155	1.474e-52	188.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus	91061|Bacilli	T	Histidine kinase	ykoH3	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_7255664_4	1131730.BAVI_25150	1.235e-99	329.0	COG0726@1|root,COG0726@2|Bacteria,1TPWK@1239|Firmicutes,4HEQ2@91061|Bacilli,1ZPWD@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_7255664_5	1403313.AXBR01000014_gene2293	3.911e-78	267.0	COG0586@1|root,COG0586@2|Bacteria,1VDM5@1239|Firmicutes,4HME5@91061|Bacilli,1ZQ9J@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD2_k127_7255664_1	1131730.BAVI_25140	3.2e-167	534.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HDYW@91061|Bacilli,1ZC45@1386|Bacillus	91061|Bacilli	M	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	ykoN	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD2_k127_7255664_2	1033734.CAET01000058_gene1901	1.635e-158	511.0	COG0586@1|root,COG0586@2|Bacteria,1UVK3@1239|Firmicutes,4IPNP@91061|Bacilli,1ZRI5@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,SNARE_assoc
HKD2_k127_7255664_6	1131730.BAVI_11199	5.866e-69	239.0	COG3584@1|root,COG3584@2|Bacteria,1UYMN@1239|Firmicutes,4HIVQ@91061|Bacilli,1ZDD1@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuiC	-	-	-	-	-	-	-	-	-	-	-	3D
HKD2_k127_7255664_3	1403313.AXBR01000013_gene1462	7.999e-127	409.0	COG0614@1|root,COG0614@2|Bacteria,1TQV7@1239|Firmicutes,4HCF3@91061|Bacilli,1ZBF0@1386|Bacillus	91061|Bacilli	P	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	iYO844.BSU33180	Peripla_BP_2
HKD2_k127_7255664_7	1403313.AXBR01000013_gene1463	2.391e-68	235.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,4HHA6@91061|Bacilli,1ZFKA@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuiD	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
HKD2_k127_7255664_0	1403313.AXBR01000013_gene1464	2.233e-256	797.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus	91061|Bacilli	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HKD2_k127_7275888_12	1403313.AXBR01000027_gene5265	1.049e-47	171.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus	91061|Bacilli	S	COG1078 HD superfamily phosphohydrolases	ywfO	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
HKD2_k127_7275888_9	1403313.AXBR01000027_gene5264	8.817e-90	297.0	COG3465@1|root,COG3465@2|Bacteria,1V6Q4@1239|Firmicutes,4HHX3@91061|Bacilli,1ZFMJ@1386|Bacillus	91061|Bacilli	-	-	ywgA	-	-	ko:K09388	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_7275888_13	941639.BCO26_2844	1.901e-24	106.0	COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,1ZITA@1386|Bacillus	91061|Bacilli	G	4-oxalocrotonate tautomerase	dmpI	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
HKD2_k127_7275888_8	1243664.CAVL020000042_gene3871	2.036e-93	310.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4HHK2@91061|Bacilli,1ZQYY@1386|Bacillus	91061|Bacilli	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HKD2_k127_7275888_10	1403313.AXBR01000027_gene5261	1.714e-85	285.0	28J0N@1|root,2Z8XT@2|Bacteria,1V1UK@1239|Firmicutes,4HD4W@91061|Bacilli,1ZBQ1@1386|Bacillus	91061|Bacilli	S	YwhD family	ywhD	-	-	-	-	-	-	-	-	-	-	-	YwhD
HKD2_k127_7275888_1	1403313.AXBR01000027_gene5260	0.0	1052.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	pbpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD2_k127_7275888_4	1403313.AXBR01000027_gene5258	6.27e-180	566.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HA7S@91061|Bacilli,1ZB9A@1386|Bacillus	91061|Bacilli	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD2_k127_7275888_11	1403313.AXBR01000027_gene5257	3.955e-61	213.0	COG4506@1|root,COG4506@2|Bacteria,1VK4E@1239|Firmicutes,4HR38@91061|Bacilli,1ZHXY@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
HKD2_k127_7275888_2	1403313.AXBR01000027_gene5256	2.5e-323	993.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus	91061|Bacilli	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HKD2_k127_7275888_14	1385514.N782_03495	2.905e-06	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7275888_6	1403313.AXBR01000027_gene5255	1.557e-152	486.0	COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus	91061|Bacilli	L	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
HKD2_k127_7275888_7	1403313.AXBR01000027_gene5254	4.929e-151	487.0	COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZC77@1386|Bacillus	91061|Bacilli	I	Belongs to the phospholipase D family. Cardiolipin synthase subfamily	clsB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HKD2_k127_7275888_0	1174504.AJTN02000194_gene4196	0.0	1242.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus	91061|Bacilli	C	COG0247 Fe-S oxidoreductase	ywjF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
HKD2_k127_7275888_3	1403313.AXBR01000027_gene5252	1.717e-214	671.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBYG@1386|Bacillus	91061|Bacilli	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	mmgA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
HKD2_k127_7275888_5	1403313.AXBR01000027_gene5249	5.882e-161	508.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_7298860_0	1403313.AXBR01000009_gene794	0.0	1090.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus	91061|Bacilli	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD2_k127_7298860_1	1403313.AXBR01000009_gene795	4.727e-315	970.0	COG1067@1|root,COG1474@1|root,COG1067@2|Bacteria,COG1474@2|Bacteria,1TP2K@1239|Firmicutes,4HB6F@91061|Bacilli,1ZBW1@1386|Bacillus	91061|Bacilli	LO	Belongs to the peptidase S16 family	lonB	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA,Lon_C
HKD2_k127_7309107_1	1403313.AXBR01000021_gene3175	1.357e-86	290.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus	91061|Bacilli	M	Penicillin-binding Protein	pbpX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD2_k127_7309107_0	1403313.AXBR01000021_gene3174	0.0	1056.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZBC0@1386|Bacillus	91061|Bacilli	M	stage V sporulation protein D	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD2_k127_7309256_0	1403313.AXBR01000005_gene1859	1.499e-194	612.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,1ZAP4@1386|Bacillus	91061|Bacilli	P	Major facilitator superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
HKD2_k127_7309256_3	1132442.KB889752_gene1332	6.303e-13	70.0	COG1289@1|root,COG1289@2|Bacteria,1UM3F@1239|Firmicutes,4HS61@91061|Bacilli,1ZR3X@1386|Bacillus	91061|Bacilli	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HKD2_k127_7309256_4	1196029.ALIM01000004_gene4290	1.414e-08	59.0	COG1289@1|root,COG1289@2|Bacteria,1UU7Y@1239|Firmicutes,4HE9J@91061|Bacilli,1ZEB5@1386|Bacillus	91061|Bacilli	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC-like,FUSC_2
HKD2_k127_7309256_1	634956.Geoth_1638	4.876e-100	332.0	COG1414@1|root,COG1414@2|Bacteria,1W784@1239|Firmicutes,4ICFU@91061|Bacilli,1WE99@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_7309256_2	1403313.AXBR01000014_gene2248	4.722e-33	128.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HKD2_k127_7311916_2	333138.LQ50_15325	2.911e-79	277.0	COG5373@1|root,COG5373@2|Bacteria,1UXZY@1239|Firmicutes,4HEQP@91061|Bacilli,1ZBHN@1386|Bacillus	91061|Bacilli	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
HKD2_k127_7311916_0	35841.BT1A1_1726	6.678e-111	369.0	COG2130@1|root,COG2130@2|Bacteria,1TQUE@1239|Firmicutes,4HCHY@91061|Bacilli,1ZC4N@1386|Bacillus	91061|Bacilli	S	N-terminal domain of oxidoreductase	yfmJ	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
HKD2_k127_7311916_1	1122915.AUGY01000032_gene7590	7.244e-93	327.0	COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,26RPW@186822|Paenibacillaceae	91061|Bacilli	S	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5,SgrR_N
HKD2_k127_7341143_11	935836.JAEL01000013_gene4519	5.513e-07	51.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,4HINQ@91061|Bacilli,1ZGEA@1386|Bacillus	91061|Bacilli	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.17.1.4,1.2.5.3	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32470	Fer2,Fer2_2
HKD2_k127_7341143_0	1307436.PBF_20643	1.942e-275	852.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZQ9N@1386|Bacillus	91061|Bacilli	F	Amidohydrolase family	allB	-	3.5.2.3,3.5.2.5	ko:K01465,ko:K01466	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00051,M00546	R01993,R02425	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD2_k127_7341143_2	1307436.PBF_20638	1.147e-106	347.0	COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HFT9@91061|Bacilli,1ZESB@1386|Bacillus	91061|Bacilli	Q	Isochorismatase family	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
HKD2_k127_7341143_3	935836.JAEL01000013_gene4524	1.909e-93	309.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,1ZFID@1386|Bacillus	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
HKD2_k127_7341143_1	935836.JAEL01000013_gene4525	8.675e-219	685.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,1ZR0K@1386|Bacillus	91061|Bacilli	H	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate	yclC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464	4.1.1.61,4.1.1.98	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	M00117	R01238,R04985,R04986,R10213	RC00391,RC03086	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
HKD2_k127_7341143_9	1196031.ALEG01000008_gene5066	1.501e-31	124.0	COG4577@1|root,COG4577@2|Bacteria,1TZHZ@1239|Firmicutes,4I8SM@91061|Bacilli,1ZHP6@1386|Bacillus	91061|Bacilli	CQ	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD2_k127_7341143_5	1121090.KB894693_gene2485	1.355e-46	180.0	2A221@1|root,30QC2@2|Bacteria,1TYE0@1239|Firmicutes,4I7I3@91061|Bacilli,1ZEHM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7341143_8	1307436.PBF_20613	3.545e-32	128.0	COG4577@1|root,COG4577@2|Bacteria,1VBMF@1239|Firmicutes,4IKCV@91061|Bacilli,1ZGGW@1386|Bacillus	91061|Bacilli	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD2_k127_7341143_4	698769.JFBD01000019_gene1986	6.676e-47	169.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,4HM6R@91061|Bacilli	91061|Bacilli	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	pduJ	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD2_k127_7341143_6	698769.JFBD01000019_gene1985	1.388e-38	153.0	COG0452@1|root,COG0452@2|Bacteria,1UIJ7@1239|Firmicutes,4HY0X@91061|Bacilli	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7341143_7	698769.JFBD01000019_gene1984	3.322e-35	136.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,4HMD4@91061|Bacilli	91061|Bacilli	CQ	Ethanolamine utilisation protein EutN/carboxysome	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
HKD2_k127_7341143_10	698769.JFBD01000019_gene1983	2.902e-10	61.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli	1239|Firmicutes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	-	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD2_k127_7369370_46	1348908.KI518605_gene3294	1.595e-36	148.0	29N94@1|root,3096Z@2|Bacteria,1V49G@1239|Firmicutes,4HHC5@91061|Bacilli,1ZH7E@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_0	1403313.AXBR01000023_gene2330	0.0	1450.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus	91061|Bacilli	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HKD2_k127_7369370_28	1403313.AXBR01000023_gene2328	2.559e-90	304.0	COG2267@1|root,COG2267@2|Bacteria,1UZM1@1239|Firmicutes,4HFJW@91061|Bacilli,1ZD5F@1386|Bacillus	91061|Bacilli	I	carboxylic ester hydrolase activity	yjaU	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HKD2_k127_7369370_38	1403313.AXBR01000023_gene2327	3.496e-61	221.0	COG0451@1|root,COG0451@2|Bacteria,1U20S@1239|Firmicutes,4IBHJ@91061|Bacilli,1ZGSD@1386|Bacillus	91061|Bacilli	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_48	1403313.AXBR01000023_gene2326	5.691e-24	102.0	2C7Y5@1|root,2ZW4E@2|Bacteria,1W5UC@1239|Firmicutes,4HZZW@91061|Bacilli,1ZJ0V@1386|Bacillus	91061|Bacilli	S	ComZ	comZ	-	-	ko:K02254	-	-	-	-	ko00000,ko02044	-	-	-	ComZ
HKD2_k127_7369370_59	1340434.AXVA01000010_gene5484	1.89e-06	50.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_13	1403313.AXBR01000023_gene2324	1.757e-168	532.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,1ZAQ1@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU11330	ACP_syn_III,ACP_syn_III_C
HKD2_k127_7369370_7	1403313.AXBR01000023_gene2323	1.363e-234	729.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
HKD2_k127_7369370_30	1403313.AXBR01000023_gene2322	4.406e-87	294.0	COG5504@1|root,COG5504@2|Bacteria,1UYP6@1239|Firmicutes,4HFSY@91061|Bacilli,1ZCYK@1386|Bacillus	91061|Bacilli	O	Zn-dependent protease	yjaZ	-	-	-	-	-	-	-	-	-	-	-	DUF2268
HKD2_k127_7369370_17	1403313.AXBR01000023_gene2321	1.885e-150	477.0	28IPR@1|root,2Z8PJ@2|Bacteria,1TPYR@1239|Firmicutes,4HBI7@91061|Bacilli,1ZAX0@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0736 family	yjbA	-	-	-	-	-	-	-	-	-	-	-	DUF3603
HKD2_k127_7369370_9	1403313.AXBR01000023_gene2320	2.449e-187	587.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,1ZCUY@1386|Bacillus	91061|Bacilli	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HKD2_k127_7369370_34	1174504.AJTN02000026_gene1816	1.657e-71	242.0	COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZFK4@1386|Bacillus	91061|Bacilli	K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress	spxA	-	-	ko:K16509	-	-	-	-	ko00000	-	-	-	ArsC
HKD2_k127_7369370_26	1403313.AXBR01000022_gene2911	2.703e-109	357.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HDV3@91061|Bacilli,1ZAV4@1386|Bacillus	91061|Bacilli	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC	mecA	GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
HKD2_k127_7369370_20	1403313.AXBR01000022_gene2909	4.002e-134	438.0	COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1ZCFD@1386|Bacillus	91061|Bacilli	S	Competence protein	coiA	-	-	ko:K06198	-	-	-	-	ko00000	-	-	-	CoiA
HKD2_k127_7369370_4	1403313.AXBR01000022_gene2908	0.0	1037.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus	91061|Bacilli	E	oligoendopeptidase F	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD2_k127_7369370_60	665952.HMPREF1015_01560	2.807e-06	51.0	2DJA0@1|root,3055R@2|Bacteria,1TXRP@1239|Firmicutes,4I6TD@91061|Bacilli,1ZK1C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_16	1403313.AXBR01000022_gene2907	6.489e-157	498.0	COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,1ZATS@1386|Bacillus	91061|Bacilli	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	yjbH	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_5
HKD2_k127_7369370_31	1403313.AXBR01000022_gene2906	3.904e-77	259.0	COG2346@1|root,COG2346@2|Bacteria,1V6JN@1239|Firmicutes,4HHQG@91061|Bacilli,1ZG81@1386|Bacillus	91061|Bacilli	S	COG2346 Truncated hemoglobins	yjbI	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD2_k127_7369370_36	1174504.AJTN02000030_gene857	3.751e-66	231.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
HKD2_k127_7369370_39	1403313.AXBR01000022_gene2904	4.427e-60	213.0	COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1ZH0U@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yjbK	-	-	-	-	-	-	-	-	-	-	-	CYTH
HKD2_k127_7369370_27	1174504.AJTN02000030_gene854	1.539e-105	346.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,1ZBM8@1386|Bacillus	91061|Bacilli	S	GTP pyrophosphokinase	yjbM	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HKD2_k127_7369370_15	1403313.AXBR01000022_gene2902	9.013e-159	501.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,1ZAQP@1386|Bacillus	91061|Bacilli	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS04895	NAD_kinase
HKD2_k127_7369370_22	1403313.AXBR01000022_gene2901	4.066e-132	426.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD2_k127_7369370_21	1403313.AXBR01000022_gene2900	2.219e-132	424.0	COG0639@1|root,COG0639@2|Bacteria,1TPCI@1239|Firmicutes,4HBD8@91061|Bacilli,1ZBK8@1386|Bacillus	91061|Bacilli	T	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP	prpE	GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.16,3.6.1.41	ko:K01090,ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD2_k127_7369370_8	1403313.AXBR01000022_gene2899	3.556e-211	664.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,1ZCSG@1386|Bacillus	91061|Bacilli	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HKD2_k127_7369370_18	1403313.AXBR01000022_gene2898	2.105e-136	437.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus	91061|Bacilli	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD2_k127_7369370_25	1174504.AJTN02000030_gene848	3.978e-121	401.0	28KI6@1|root,2ZA3G@2|Bacteria,1UYE9@1239|Firmicutes,4HB9Y@91061|Bacilli,1ZF3A@1386|Bacillus	91061|Bacilli	S	Spore germination B3/ GerAC like, C-terminal	gerXC	-	-	-	-	-	-	-	-	-	-	-	Spore_GerAC
HKD2_k127_7369370_24	1174504.AJTN02000030_gene848	1.807e-122	404.0	28KI6@1|root,2ZA3G@2|Bacteria,1UYE9@1239|Firmicutes,4HB9Y@91061|Bacilli,1ZF3A@1386|Bacillus	91061|Bacilli	S	Spore germination B3/ GerAC like, C-terminal	gerXC	-	-	-	-	-	-	-	-	-	-	-	Spore_GerAC
HKD2_k127_7369370_12	1174504.AJTN02000030_gene847	2.208e-169	546.0	COG0697@1|root,COG0697@2|Bacteria,1TSX6@1239|Firmicutes,4HCV4@91061|Bacilli,1ZCUJ@1386|Bacillus	91061|Bacilli	EG	Bacillus/Clostridium GerA spore germination protein	gerXA	-	-	-	-	-	-	-	-	-	-	-	GerA
HKD2_k127_7369370_23	1174504.AJTN02000030_gene846	2.831e-123	405.0	COG0814@1|root,COG0814@2|Bacteria,1UIZI@1239|Firmicutes,4ISYF@91061|Bacilli,1ZSGZ@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
HKD2_k127_7369370_50	1403313.AXBR01000022_gene2896	8.302e-18	91.0	2BFSK@1|root,329MG@2|Bacteria,1UC0H@1239|Firmicutes,4INGE@91061|Bacilli,1ZNFW@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_43	1403313.AXBR01000022_gene2895	5.605e-42	157.0	2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli,1ZHZZ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1360)	yjcA	-	-	-	-	-	-	-	-	-	-	-	DUF1360
HKD2_k127_7369370_42	1403313.AXBR01000022_gene2894	1.281e-49	181.0	2CY4V@1|root,32T3F@2|Bacteria,1VDQ0@1239|Firmicutes,4HKEQ@91061|Bacilli,1ZIB4@1386|Bacillus	91061|Bacilli	S	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YhcN_YlaJ
HKD2_k127_7369370_33	1403313.AXBR01000022_gene2893	6.879e-75	254.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,4HH0C@91061|Bacilli,1ZFW2@1386|Bacillus	91061|Bacilli	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HKD2_k127_7369370_11	1403313.AXBR01000022_gene2892	3.962e-178	561.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,4H9W9@91061|Bacilli,1ZAW8@1386|Bacillus	91061|Bacilli	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
HKD2_k127_7369370_37	997296.PB1_02750	2.753e-64	221.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,4HIW4@91061|Bacilli,1ZG67@1386|Bacillus	91061|Bacilli	S	stage V sporulation protein	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HKD2_k127_7369370_55	665952.HMPREF1015_01535	3.053e-10	61.0	2DRND@1|root,33CCV@2|Bacteria,1VNPA@1239|Firmicutes,4HR66@91061|Bacilli,1ZJXX@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (Tiny_TM_bacill)	-	-	-	-	-	-	-	-	-	-	-	-	Tiny_TM_bacill
HKD2_k127_7369370_56	1385514.N782_03495	1.74e-08	56.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_44	1307436.PBF_03780	6.05e-37	140.0	2E36V@1|root,32Y6J@2|Bacteria,1VFDU@1239|Firmicutes,4HY6K@91061|Bacilli,1ZHWX@1386|Bacillus	91061|Bacilli	S	Stage VI sporulation protein F	spoVIF	-	-	-	-	-	-	-	-	-	-	-	SpoVIF
HKD2_k127_7369370_3	1403313.AXBR01000022_gene2888	0.0	1163.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZCF6@1386|Bacillus	91061|Bacilli	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CoiA,UvrD-helicase,UvrD_C
HKD2_k127_7369370_57	1403313.AXBR01000022_gene2887	2.827e-07	57.0	2B8Q1@1|root,321ZN@2|Bacteria,1UCBX@1239|Firmicutes,4INUC@91061|Bacilli,1ZNYN@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_40	1403313.AXBR01000022_gene2886	1.071e-59	210.0	2CFVW@1|root,32S2K@2|Bacteria,1VBNQ@1239|Firmicutes,4HMD7@91061|Bacilli,1ZGPY@1386|Bacillus	91061|Bacilli	S	Spore Coat Protein X and V domain	cotX	-	-	ko:K06342	-	-	-	-	ko00000	-	-	-	Coat_X
HKD2_k127_7369370_49	1403313.AXBR01000022_gene2885	4.149e-20	92.0	29TCR@1|root,30EJV@2|Bacteria,1UCNI@1239|Firmicutes,4IP4R@91061|Bacilli,1ZPDI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_47	1403313.AXBR01000023_gene2643	1.951e-29	117.0	COG0431@1|root,COG0431@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli,1ZBNA@1386|Bacillus	91061|Bacilli	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD2_k127_7369370_41	189426.PODO_15315	9.271e-53	192.0	COG1309@1|root,COG1309@2|Bacteria,1VG7Z@1239|Firmicutes,4IRRY@91061|Bacilli,26VPV@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial transcriptional repressor C-terminal	ydeS	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
HKD2_k127_7369370_14	665952.HMPREF1015_03172	4.368e-163	524.0	COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus	91061|Bacilli	F	Xanthine uracil	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
HKD2_k127_7369370_10	1132442.KB889752_gene419	1.33e-186	587.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZB5H@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_7369370_45	634956.Geoth_3013	6.271e-37	143.0	COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,1WGF1@129337|Geobacillus	91061|Bacilli	S	FR47-like protein	yjcF	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD2_k127_7369370_35	1403313.AXBR01000022_gene2883	1.106e-66	231.0	COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli,1ZG9R@1386|Bacillus	91061|Bacilli	J	Belongs to the 2H phosphoesterase superfamily. YjcG family	yjcG	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD2_k127_7369370_19	1403313.AXBR01000022_gene2882	2.6e-135	433.0	COG2382@1|root,COG2382@2|Bacteria,1UCAC@1239|Firmicutes,4HC02@91061|Bacilli,1ZBAQ@1386|Bacillus	91061|Bacilli	P	COG2382 Enterochelin esterase and related enzymes	yjcH	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
HKD2_k127_7369370_32	1403313.AXBR01000022_gene2881	1.832e-76	260.0	COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,1ZFQE@1386|Bacillus	91061|Bacilli	I	COG1267 Phosphatidylglycerophosphatase A and related proteins	pgpA	-	-	-	-	-	-	-	-	-	-	-	PgpA
HKD2_k127_7369370_5	1117379.BABA_05141	2.492e-305	941.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_7369370_54	1340434.AXVA01000016_gene701	4.021e-11	70.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7369370_6	666686.B1NLA3E_12285	8.433e-271	848.0	COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,4HUF7@91061|Bacilli,1ZS1R@1386|Bacillus	91061|Bacilli	KQ	COG3284 Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
HKD2_k127_7369370_2	666686.B1NLA3E_12280	0.0	1320.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,1ZAQW@1386|Bacillus	91061|Bacilli	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14,6.4.1.6	ko:K01473,ko:K10855	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
HKD2_k127_7369370_1	666686.B1NLA3E_12275	0.0	1441.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli,1ZDFI@1386|Bacillus	91061|Bacilli	EQ	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit	-	-	6.4.1.6	ko:K10854	-	-	-	-	ko00000,ko01000	-	-	-	Hydantoinase_B
HKD2_k127_7369370_29	665952.HMPREF1015_02194	3.118e-88	291.0	COG4647@1|root,COG4647@2|Bacteria,1TTB5@1239|Firmicutes,4HCXE@91061|Bacilli,1ZEXW@1386|Bacillus	91061|Bacilli	Q	Acetone carboxylase gamma subunit	-	-	6.4.1.6	ko:K10856	-	-	-	-	ko00000,ko01000	-	-	-	Acetone_carb_G
HKD2_k127_7402024_3	1397693.KK211187_gene115	7.14e-86	287.0	COG0477@1|root,COG2814@2|Bacteria,1UY3H@1239|Firmicutes,4HDV2@91061|Bacilli,3WER7@539002|Bacillales incertae sedis	91061|Bacilli	EGP	Mycoplasma MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_7402024_2	324057.Pjdr2_0977	1.539e-198	622.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,4HDEY@91061|Bacilli,26UQN@186822|Paenibacillaceae	91061|Bacilli	G	Periplasmic binding protein domain	-	-	-	ko:K10543,ko:K10546	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	Peripla_BP_4
HKD2_k127_7402024_0	1131730.BAVI_03834	4.341e-279	863.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus	91061|Bacilli	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
HKD2_k127_7402024_1	1305836.AXVE01000001_gene2797	9.43e-209	653.0	COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,4HBDM@91061|Bacilli,26ECX@186818|Planococcaceae	91061|Bacilli	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10544,ko:K10547	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	BPD_transp_2
HKD2_k127_7402024_4	1131730.BAVI_03824	1.335e-78	265.0	COG1879@1|root,COG1879@2|Bacteria,1TQZS@1239|Firmicutes,4HCUS@91061|Bacilli,1ZB0G@1386|Bacillus	91061|Bacilli	G	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HKD2_k127_7443468_5	1403313.AXBR01000027_gene5238	5.881e-70	238.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZC28@1386|Bacillus	91061|Bacilli	G	fructose-1,6-bisphosphatase	glpX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
HKD2_k127_7443468_0	1403313.AXBR01000027_gene5237	2.166e-257	796.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,1ZBN9@1386|Bacillus	91061|Bacilli	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD2_k127_7443468_6	1211814.CAPG01000064_gene3018	1.816e-38	144.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli,1ZQBD@1386|Bacillus	91061|Bacilli	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HKD2_k127_7443468_3	1403313.AXBR01000027_gene5235	2.641e-105	347.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,1ZBMX@1386|Bacillus	91061|Bacilli	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iYO844.BSU37060	TK
HKD2_k127_7443468_4	1227360.C176_03653	3.313e-78	268.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,4HJKG@91061|Bacilli,26HHN@186818|Planococcaceae	91061|Bacilli	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD2_k127_7443468_1	1034347.CAHJ01000030_gene3803	1.774e-194	610.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,1ZCE9@1386|Bacillus	91061|Bacilli	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD2_k127_7443468_2	1243664.CAVL020000041_gene4035	9.75e-119	388.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,1ZBSE@1386|Bacillus	91061|Bacilli	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
HKD2_k127_746923_2	1403313.AXBR01000007_gene407	1.788e-80	271.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,1ZBRQ@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacB	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD2_k127_746923_0	1403313.AXBR01000007_gene410	1.857e-125	407.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HAX6@91061|Bacilli,1ZB6Q@1386|Bacillus	91061|Bacilli	P	Superoxide dismutase	sodF	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF2935,Sod_Fe_C,Sod_Fe_N
HKD2_k127_746923_3	1340434.AXVA01000010_gene5484	2.131e-09	61.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_746923_1	1403313.AXBR01000007_gene411	8.491e-82	274.0	29P42@1|root,30A29@2|Bacteria,1V423@1239|Firmicutes,4HH8N@91061|Bacilli,1ZG69@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3907)	ypuI	-	-	-	-	-	-	-	-	-	-	-	DUF3907
HKD2_k127_7479561_2	1403313.AXBR01000009_gene830	1.986e-59	206.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05640	FAD_binding_2,Succ_DH_flav_C
HKD2_k127_7479561_1	1174504.AJTN02000191_gene4250	2.537e-99	329.0	COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,1ZBB5@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iYO844.BSU28450	Sdh_cyt
HKD2_k127_7479561_3	1403313.AXBR01000009_gene832	1.011e-56	201.0	COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,1ZQN2@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2507)	yslB	-	-	-	-	-	-	-	-	-	-	-	DUF2507
HKD2_k127_7479561_0	1403313.AXBR01000009_gene833	3.423e-200	632.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZDA6@1386|Bacillus	91061|Bacilli	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
HKD2_k127_7489760_7	1408303.JNJJ01000130_gene1851	8.071e-09	56.0	29S78@1|root,30DBR@2|Bacteria,1UB46@1239|Firmicutes,4IMGS@91061|Bacilli,1ZK4I@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7489760_5	1174504.AJTN02000183_gene61	3.131e-41	158.0	COG4929@1|root,COG4929@2|Bacteria,1VCKN@1239|Firmicutes,4HN4G@91061|Bacilli,1ZRZZ@1386|Bacillus	91061|Bacilli	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
HKD2_k127_7489760_0	1403313.AXBR01000002_gene4140	1.491e-135	441.0	COG4872@1|root,COG4872@2|Bacteria,1TT9X@1239|Firmicutes,4HG7T@91061|Bacilli,1ZESZ@1386|Bacillus	91061|Bacilli	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
HKD2_k127_7489760_4	1403313.AXBR01000002_gene4139	1.162e-58	205.0	COG1695@1|root,COG1695@2|Bacteria,1VA8U@1239|Firmicutes,4HKPC@91061|Bacilli,1ZGYN@1386|Bacillus	91061|Bacilli	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HKD2_k127_7489760_1	1403313.AXBR01000002_gene4138	4.365e-79	267.0	COG4709@1|root,COG4709@2|Bacteria,1VBDQ@1239|Firmicutes,4HM00@91061|Bacilli,1ZFMM@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1700)	XK27_04830	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HKD2_k127_7489760_2	1403313.AXBR01000002_gene4137	3.544e-67	237.0	COG3595@1|root,COG3595@2|Bacteria,1V3YZ@1239|Firmicutes,4HHX2@91061|Bacilli,1ZGDJ@1386|Bacillus	91061|Bacilli	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HKD2_k127_7489760_3	1236973.JCM9157_1929	3.85e-63	220.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZN0V@1386|Bacillus	91061|Bacilli	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
HKD2_k127_7506045_1	1294265.JCM21738_4840	2.543e-52	185.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1ZAT8@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_7506045_0	1117379.BABA_01110	1.691e-166	537.0	COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,1ZBXH@1386|Bacillus	91061|Bacilli	M	G5	nlpD	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
HKD2_k127_7513664_0	573.JG24_11065	1.611e-21	104.0	COG2755@1|root,COG2755@2|Bacteria,1NFJ5@1224|Proteobacteria,1SEHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD2_k127_7514384_2	768704.Desmer_1845	7.85e-12	66.0	COG1846@1|root,COG1846@2|Bacteria,1VCKC@1239|Firmicutes,25CQE@186801|Clostridia	186801|Clostridia	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD2_k127_7514384_1	1340434.AXVA01000008_gene3496	4.821e-53	190.0	COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,1ZGHR@1386|Bacillus	91061|Bacilli	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD2_k127_7514384_0	935836.JAEL01000025_gene2373	6.068e-79	272.0	COG1366@1|root,COG1366@2|Bacteria,1V6ME@1239|Firmicutes,4HJGU@91061|Bacilli,1ZCN1@1386|Bacillus	91061|Bacilli	T	STAS domain	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	STAS
HKD2_k127_7516004_6	1184267.A11Q_693	7.002e-15	79.0	COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,42SWX@68525|delta/epsilon subdivisions,2MU56@213481|Bdellovibrionales,2WPJ0@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	dehydratase	maoC	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
HKD2_k127_7516004_2	1200792.AKYF01000010_gene2760	4.474e-62	232.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26QU5@186822|Paenibacillaceae	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
HKD2_k127_7516004_0	345219.Bcoa_0508	0.0	1160.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,4HDSI@91061|Bacilli,1ZFF4@1386|Bacillus	91061|Bacilli	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
HKD2_k127_7516004_4	1122918.KB907273_gene3521	1.926e-30	122.0	2EURH@1|root,333HF@2|Bacteria,1VEGJ@1239|Firmicutes,4HP3K@91061|Bacilli,270E6@186822|Paenibacillaceae	91061|Bacilli	S	Transcriptional regulator protein (SplA)	-	-	-	ko:K06315	-	-	-	-	ko00000,ko03000	-	-	-	SplA
HKD2_k127_7516004_1	1169144.KB910932_gene825	1.319e-213	666.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,4HACB@91061|Bacilli,1ZBPU@1386|Bacillus	91061|Bacilli	L	Spore photoproduct lyase	splB	GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD2_k127_7516004_7	1196324.A374_13545	1.069e-06	53.0	2EQG8@1|root,34CAX@2|Bacteria,1W23C@1239|Firmicutes,4I1CM@91061|Bacilli	91061|Bacilli	S	Spore germination protein gerPA/gerPF	-	-	-	-	-	-	-	-	-	-	-	-	gerPA
HKD2_k127_7516004_3	1121090.KB894687_gene775	2.141e-34	133.0	2EQG8@1|root,33IXY@2|Bacteria,1W1ME@1239|Firmicutes,4I0CE@91061|Bacilli,1ZJH9@1386|Bacillus	91061|Bacilli	S	Spore germination protein gerPA/gerPF	ydgB	-	-	-	-	-	-	-	-	-	-	-	gerPA
HKD2_k127_7516004_5	326423.RBAM_007950	2.245e-30	121.0	2EQG8@1|root,33I29@2|Bacteria,1VMF2@1239|Firmicutes,4IAND@91061|Bacilli,1ZJ0K@1386|Bacillus	91061|Bacilli	S	Spore germination protein gerPA/gerPF	ydgA	-	-	-	-	-	-	-	-	-	-	-	gerPA
HKD2_k127_7518238_4	1211035.CD30_06440	3.526e-29	117.0	COG2972@1|root,COG2972@2|Bacteria,1VWNX@1239|Firmicutes,4HXJQ@91061|Bacilli	91061|Bacilli	T	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
HKD2_k127_7518238_0	1174504.AJTN02000193_gene4040	6.567e-162	518.0	COG0500@1|root,COG2226@2|Bacteria,1UIHW@1239|Firmicutes,4HCCW@91061|Bacilli,1ZRT4@1386|Bacillus	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HKD2_k127_7518238_2	1305836.AXVE01000011_gene801	1.178e-85	287.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,26D03@186818|Planococcaceae	91061|Bacilli	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
HKD2_k127_7518238_1	1403313.AXBR01000010_gene1132	1.177e-149	481.0	COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus	91061|Bacilli	T	Histidine kinase	vraS	-	2.7.13.3	ko:K07681,ko:K11617	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
HKD2_k127_7518238_3	1403313.AXBR01000010_gene1133	8.051e-67	232.0	COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,1ZDPB@1386|Bacillus	91061|Bacilli	S	Cell wall-active antibiotics response 4TMS YvqF	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
HKD2_k127_7519163_9	1395513.P343_00515	1.161e-11	66.0	COG1647@1|root,COG1647@2|Bacteria,1TVX4@1239|Firmicutes,4HFF2@91061|Bacilli,26PSA@186821|Sporolactobacillaceae	91061|Bacilli	S	Serine hydrolase (FSH1)	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
HKD2_k127_7519163_3	1174504.AJTN02000219_gene1053	1.155e-89	299.0	COG0500@1|root,COG2226@2|Bacteria,1UW6A@1239|Firmicutes,4HHM5@91061|Bacilli,1ZDRF@1386|Bacillus	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
HKD2_k127_7519163_6	1501230.ET33_17400	5.127e-29	116.0	2BQ7R@1|root,32J2G@2|Bacteria,1U1CG@1239|Firmicutes,4IAUS@91061|Bacilli,2737H@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HKD2_k127_7519163_7	1132442.KB889752_gene313	3.152e-23	100.0	29T7W@1|root,30EEP@2|Bacteria,1UCGG@1239|Firmicutes,4INYU@91061|Bacilli,1ZP4Y@1386|Bacillus	91061|Bacilli	S	YppF-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YppF
HKD2_k127_7519163_4	1200792.AKYF01000019_gene4579	5.192e-69	238.0	COG0526@1|root,COG0526@2|Bacteria,1V2DU@1239|Firmicutes,4HGQZ@91061|Bacilli,272NT@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
HKD2_k127_7519163_8	1120972.AUMH01000032_gene2628	2.108e-15	79.0	COG1018@1|root,COG1018@2|Bacteria,1VKC9@1239|Firmicutes,4HRAY@91061|Bacilli,27AHZ@186823|Alicyclobacillaceae	91061|Bacilli	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	Fer2
HKD2_k127_7519163_2	562970.Btus_0957	1.617e-125	408.0	COG0346@1|root,COG0346@2|Bacteria,1TRBJ@1239|Firmicutes,4HADI@91061|Bacilli,279AV@186823|Alicyclobacillaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HKD2_k127_7519163_1	1243664.CAVL020000048_gene2515	1.539e-151	483.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,4HBPD@91061|Bacilli,1ZQAC@1386|Bacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HKD2_k127_7519163_5	1403313.AXBR01000013_gene1503	3.709e-67	231.0	2E71A@1|root,331JZ@2|Bacteria,1VG6F@1239|Firmicutes,4HNSV@91061|Bacilli,1ZFRN@1386|Bacillus	91061|Bacilli	S	YugN-like family	yugN	-	-	-	-	-	-	-	-	-	-	-	YugN
HKD2_k127_7519163_0	1231057.AMGD01000041_gene730	8.547e-203	638.0	COG0477@1|root,COG2814@2|Bacteria,1TQ7H@1239|Firmicutes,4HB0I@91061|Bacilli,26E2W@186818|Planococcaceae	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	ydeG3	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,Sugar_tr
HKD2_k127_7524494_3	1227360.C176_00840	1.123e-141	456.0	COG3290@1|root,COG3290@2|Bacteria,1TQHC@1239|Firmicutes,4HAH4@91061|Bacilli,26GKW@186818|Planococcaceae	91061|Bacilli	T	Sensor_kinase_SpoOB-type, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,SPOB_a
HKD2_k127_7524494_5	1174504.AJTN02000026_gene1816	6.919e-57	200.0	COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZFK4@1386|Bacillus	91061|Bacilli	K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress	spxA	-	-	ko:K16509	-	-	-	-	ko00000	-	-	-	ArsC
HKD2_k127_7524494_4	1403313.AXBR01000015_gene2190	7.236e-132	424.0	COG1741@1|root,COG1741@2|Bacteria,1TSV4@1239|Firmicutes,4HGT6@91061|Bacilli,1ZDMW@1386|Bacillus	91061|Bacilli	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD2_k127_7524494_1	1131730.BAVI_09546	5.863e-213	662.0	COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,4HMYE@91061|Bacilli,1ZM90@1386|Bacillus	91061|Bacilli	S	Belongs to the pirin family	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
HKD2_k127_7524494_0	1078085.HMPREF1210_01398	0.0	1482.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,1V9TE@1239|Firmicutes,4HPS1@91061|Bacilli	91061|Bacilli	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
HKD2_k127_7524494_2	1078085.HMPREF1210_01397	4.532e-157	502.0	COG2370@1|root,COG2370@2|Bacteria,1V704@1239|Firmicutes,4HINW@91061|Bacilli	91061|Bacilli	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
HKD2_k127_7524494_7	1347086.CCBA010000009_gene1406	1.276e-21	97.0	COG1404@1|root,COG4509@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4509@2|Bacteria,COG4733@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	prtP	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CW_binding_1,CW_binding_2,Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5
HKD2_k127_7524494_9	1340434.AXVA01000004_gene2641	6.915e-08	55.0	COG1653@1|root,COG3757@1|root,COG4733@1|root,COG1653@2|Bacteria,COG3757@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	lyc	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17,3.2.1.8	ko:K01181,ko:K01185,ko:K02027,ko:K07273,ko:K07451,ko:K17315,ko:K17318	ko02010,map02010	M00207,M00603,M00605	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048	3.A.1.1,3.A.1.1.24,3.A.1.1.29,3.A.1.1.30,3.A.1.1.9	-	-	Glyco_hydro_25,LysM,Phage-tail_3
HKD2_k127_7524494_6	646529.Desaci_2172	3.491e-26	108.0	2EG90@1|root,33A0T@2|Bacteria,1VMNR@1239|Firmicutes,2552Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7524494_10	871968.DESME_03440	5.384e-06	49.0	2DW9N@1|root,33Z70@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HKD2_k127_7531075_7	1403313.AXBR01000027_gene5212	3.208e-54	193.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,1ZGET@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
HKD2_k127_7531075_2	1174504.AJTN02000012_gene3913	4.526e-276	852.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,1ZB62@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10965	ATP-synt_ab,ATP-synt_ab_N
HKD2_k127_7531075_3	1403313.AXBR01000027_gene5214	1.243e-148	473.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,1ZCKT@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSB619.SA_RS10970,iYO844.BSU36820	ATP-synt
HKD2_k127_7531075_1	1403313.AXBR01000027_gene5215	1.974e-302	930.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,1ZB13@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD2_k127_7531075_6	1403313.AXBR01000027_gene5216	2.972e-74	253.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HKD2_k127_7531075_5	1403313.AXBR01000027_gene5217	1.091e-80	272.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
HKD2_k127_7531075_9	1403313.AXBR01000027_gene5218	1.802e-30	121.0	COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,1ZIWP@1386|Bacillus	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD2_k127_7531075_4	1403313.AXBR01000027_gene5219	3.871e-115	374.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,1ZB02@1386|Bacillus	91061|Bacilli	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HKD2_k127_7531075_8	1403313.AXBR01000027_gene5220	5.117e-41	154.0	2AGCB@1|root,316I0@2|Bacteria,1V7QK@1239|Firmicutes,4HJCW@91061|Bacilli	91061|Bacilli	S	ATP synthase	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
HKD2_k127_7531075_10	935837.JAEK01000003_gene4082	1.979e-26	111.0	COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,1ZJ1K@1386|Bacillus	91061|Bacilli	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HKD2_k127_7531075_0	1403313.AXBR01000027_gene5221	0.0	1008.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	prtS	-	3.4.21.110,3.4.21.96	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5
HKD2_k127_7535258_5	1395513.P343_00515	5.65e-09	57.0	COG1647@1|root,COG1647@2|Bacteria,1TVX4@1239|Firmicutes,4HFF2@91061|Bacilli,26PSA@186821|Sporolactobacillaceae	91061|Bacilli	S	Serine hydrolase (FSH1)	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
HKD2_k127_7535258_2	1536774.H70357_26050	2.909e-37	145.0	COG0789@1|root,COG0789@2|Bacteria,1VB69@1239|Firmicutes,4HTK2@91061|Bacilli,26Z8Z@186822|Paenibacillaceae	91061|Bacilli	K	MerR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD2_k127_7535258_0	1536774.H70357_26055	2.682e-63	218.0	COG0599@1|root,COG0599@2|Bacteria,1V78I@1239|Firmicutes,4HKFY@91061|Bacilli,26XM9@186822|Paenibacillaceae	91061|Bacilli	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
HKD2_k127_7535258_3	1174504.AJTN02000038_gene2365	5.078e-16	79.0	29T85@1|root,30EF0@2|Bacteria,1UCGU@1239|Firmicutes,4INZ7@91061|Bacilli,1ZP5G@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7535258_1	398512.JQKC01000013_gene1477	9.508e-50	179.0	COG4551@1|root,COG4551@2|Bacteria,1V7MU@1239|Firmicutes,24NAA@186801|Clostridia,3WPZA@541000|Ruminococcaceae	186801|Clostridia	S	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7535258_4	1347086.CCBA010000019_gene1137	1.654e-11	64.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus	91061|Bacilli	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09935	ACT,PDT
HKD2_k127_7547312_1	315749.Bcer98_0395	6.125e-10	60.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD2_k127_7547312_0	1405.DJ92_3048	1.154e-314	973.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus	91061|Bacilli	P	COG2217 Cation transport ATPase	zosA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
HKD2_k127_7561_3	441769.ABFU01000001_gene3054	3.873e-40	149.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HKD2_k127_7561_4	1403313.AXBR01000028_gene5101	9e-26	108.0	2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,4HQTK@91061|Bacilli,1ZIZ5@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF370)	yaaB	-	-	-	-	-	-	-	-	-	-	-	DUF370
HKD2_k127_7561_1	1174504.AJTN02000193_gene4176	0.0	1153.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD2_k127_7561_0	1174504.AJTN02000193_gene4177	0.0	1426.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD2_k127_7561_2	1174504.AJTN02000193_gene4178	1.682e-145	469.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus	91061|Bacilli	T	HD domain	M1-161	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
HKD2_k127_7604851_1	935836.JAEL01000012_gene5149	1.023e-151	486.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,4HAE0@91061|Bacilli,1ZD0Q@1386|Bacillus	91061|Bacilli	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
HKD2_k127_7604851_10	1396.DJ87_1625	3.242e-36	138.0	2C2HE@1|root,33NUY@2|Bacteria,1VPQ8@1239|Firmicutes,4HSUK@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2262
HKD2_k127_7604851_0	1196323.ALKF01000151_gene1389	4.87e-162	531.0	COG1680@1|root,COG1680@2|Bacteria,1TRQD@1239|Firmicutes,4HER5@91061|Bacilli,26VXZ@186822|Paenibacillaceae	91061|Bacilli	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD2_k127_7604851_12	1268072.PSAB_19585	1.654e-24	106.0	2CM6T@1|root,344XD@2|Bacteria,1W068@1239|Firmicutes,4HYKV@91061|Bacilli,272KT@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7604851_4	1347368.HG964407_gene6900	8.993e-106	347.0	COG0745@1|root,COG0745@2|Bacteria,1TRK5@1239|Firmicutes,4HE4N@91061|Bacilli,1ZDIJ@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_7604851_3	1347368.HG964407_gene6899	5.607e-121	396.0	COG0642@1|root,COG2205@2|Bacteria,1TPK5@1239|Firmicutes,4HC46@91061|Bacilli,1ZBGU@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD2_k127_7604851_2	1347368.HG964407_gene6898	2.25e-143	461.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HC5D@91061|Bacilli,1ZDHR@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_7604851_5	1384057.CD33_12840	1.844e-75	259.0	COG1277@1|root,2Z99C@2|Bacteria,1TQMN@1239|Firmicutes,4HRBJ@91061|Bacilli	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
HKD2_k127_7604851_9	935837.JAEK01000015_gene5039	3.152e-46	170.0	29SG3@1|root,30DM1@2|Bacteria,1UBES@1239|Firmicutes,4IMTD@91061|Bacilli,1ZKSZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7604851_13	696281.Desru_3205	3.744e-10	61.0	295SS@1|root,2ZT42@2|Bacteria,1W3ZE@1239|Firmicutes,24W0I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7604851_8	1499680.CCFE01000011_gene780	6.823e-61	213.0	2EEDK@1|root,3387P@2|Bacteria,1VIPR@1239|Firmicutes,4HW7J@91061|Bacilli,1ZJNK@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7604851_6	1408424.JHYI01000018_gene3195	2.657e-71	248.0	2DZYS@1|root,32VNG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7604851_7	1007103.AFHW01000001_gene4883	2.48e-67	234.0	COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,4HG0Y@91061|Bacilli,26WH9@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	yobS	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
HKD2_k127_7627580_3	1211814.CAPG01000002_gene6	1.256e-100	334.0	COG0477@1|root,COG2814@2|Bacteria,1TR1D@1239|Firmicutes,4HA4Z@91061|Bacilli,1ZB9Z@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
HKD2_k127_7627580_6	1347369.CCAD010000013_gene2556	5.136e-29	121.0	2E8IN@1|root,332WP@2|Bacteria,1VFCT@1239|Firmicutes,4HQ8D@91061|Bacilli,1ZI4F@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7627580_2	1033734.CAET01000014_gene1751	1.029e-154	499.0	28MSG@1|root,2Z80Z@2|Bacteria,1TQD3@1239|Firmicutes,4HB4M@91061|Bacilli,1ZQPW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2515)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2515
HKD2_k127_7627580_1	1340434.AXVA01000024_gene3889	5.386e-279	869.0	COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZBBW@1386|Bacillus	91061|Bacilli	I	COG1657 Squalene cyclase	sqhC	-	4.2.1.137	ko:K18115	-	-	-	-	ko00000,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
HKD2_k127_7627580_4	1347369.CCAD010000023_gene1495	1.684e-95	319.0	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,4HHTQ@91061|Bacilli,1ZE62@1386|Bacillus	91061|Bacilli	E	Belongs to the arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
HKD2_k127_7627580_0	1121091.AUMP01000065_gene2956	0.0	1007.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,4HD5Z@91061|Bacilli	91061|Bacilli	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
HKD2_k127_7627580_5	1347087.CBYO010000007_gene1127	1.001e-43	164.0	2AT4W@1|root,31IM1@2|Bacteria,1V6VI@1239|Firmicutes,4HIHD@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7649697_4	1403313.AXBR01000029_gene5116	1.208e-75	257.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,1ZFRP@1386|Bacillus	91061|Bacilli	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
HKD2_k127_7649697_5	1403313.AXBR01000029_gene5117	1.82e-75	257.0	COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus	91061|Bacilli	Q	Isochorismatase family	yaaI	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HKD2_k127_7649697_6	1174504.AJTN02000176_gene2069	6.467e-14	72.0	29S5T@1|root,30DAB@2|Bacteria,1UB2G@1239|Firmicutes,4IMF9@91061|Bacilli,1ZK0W@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7649697_1	1403313.AXBR01000029_gene5120	1.116e-242	753.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1ZCBQ@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD2_k127_7649697_2	1174504.AJTN02000162_gene1588	4.674e-193	610.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD2_k127_7649697_0	1403313.AXBR01000029_gene5122	1.046e-282	872.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,1ZC91@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HKD2_k127_7649697_3	1403313.AXBR01000029_gene5123	5.4e-131	425.0	28JUG@1|root,2Z9JI@2|Bacteria,1UYYT@1239|Firmicutes,4HC3E@91061|Bacilli,1ZBYK@1386|Bacillus	91061|Bacilli	S	YaaC-like Protein	yaaC	-	-	-	-	-	-	-	-	-	-	-	YaaC
HKD2_k127_76720_2	1403313.AXBR01000013_gene1344	6.324e-72	246.0	29S2U@1|root,30D7B@2|Bacteria,1UAY6@1239|Firmicutes,4IMB5@91061|Bacilli,1ZJPR@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_76720_3	35841.BT1A1_2893	3.367e-26	109.0	COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,1ZHZV@1386|Bacillus	91061|Bacilli	U	Preprotein translocase subunit SecG	secG	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HKD2_k127_76720_1	997296.PB1_09632	2.395e-138	441.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,1ZAVD@1386|Bacillus	91061|Bacilli	S	Carboxylesterase	est	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
HKD2_k127_76720_0	1403313.AXBR01000013_gene1347	0.0	1323.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus	91061|Bacilli	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HKD2_k127_779485_3	1403313.AXBR01000022_gene2772	2.964e-126	408.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli,1ZCID@1386|Bacillus	91061|Bacilli	EP	binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HKD2_k127_779485_2	1403313.AXBR01000022_gene2773	1.53e-150	481.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus	91061|Bacilli	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K02033,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD2_k127_779485_1	1174504.AJTN02000013_gene3845	1.54e-156	499.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZE15@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HKD2_k127_779485_0	1403313.AXBR01000022_gene2775	3.726e-165	524.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD2_k127_779485_6	1403313.AXBR01000022_gene2777	4.826e-82	275.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,1ZGQ9@1386|Bacillus	91061|Bacilli	I	Acyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD2_k127_779485_7	1403313.AXBR01000022_gene2782	4.48e-76	258.0	COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,1ZFR7@1386|Bacillus	91061|Bacilli	M	COG1247 Sortase and related acyltransferases	ywnH	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
HKD2_k127_779485_4	1403313.AXBR01000022_gene2787	1.623e-118	385.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,1ZCQT@1386|Bacillus	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HKD2_k127_779485_5	1403313.AXBR01000022_gene2788	2.751e-96	321.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,1ZAX2@1386|Bacillus	91061|Bacilli	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
HKD2_k127_779485_8	1121090.KB894692_gene2311	8.983e-16	78.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,1ZFNE@1386|Bacillus	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU38290	TMP-TENI
HKD2_k127_7850841_3	1385514.N782_03495	3.781e-06	49.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7850841_0	1403313.AXBR01000002_gene4244	8.447e-214	666.0	COG0535@1|root,COG0535@2|Bacteria,1TRC8@1239|Firmicutes,4HA9Q@91061|Bacilli,1ZAVK@1386|Bacillus	91061|Bacilli	S	YfkB-like domain	yfkA	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,YfkB
HKD2_k127_7850841_2	1403313.AXBR01000002_gene4245	1.119e-134	433.0	28IN6@1|root,2Z8NK@2|Bacteria,1TR7N@1239|Firmicutes,4HBDQ@91061|Bacilli,1ZBTH@1386|Bacillus	91061|Bacilli	S	YfkD-like protein	yfkD	-	-	-	-	-	-	-	-	-	-	-	YfkD
HKD2_k127_7850841_1	1403313.AXBR01000002_gene4246	1.422e-178	564.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,4HB3X@91061|Bacilli,1ZC9V@1386|Bacillus	91061|Bacilli	P	COG0387 Ca2 H antiporter	cax	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
HKD2_k127_7854490_0	1403313.AXBR01000008_gene736	8.423e-129	418.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HKD2_k127_7854490_1	1403313.AXBR01000008_gene737	8.608e-74	254.0	COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,4HHEY@91061|Bacilli,1ZDIR@1386|Bacillus	91061|Bacilli	S	membrane	yrbG	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD2_k127_785807_3	1430331.EP10_12860	7.729e-21	103.0	COG3935@1|root,COG3935@2|Bacteria,1W6YH@1239|Firmicutes,4I46Y@91061|Bacilli,1WHNM@129337|Geobacillus	91061|Bacilli	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HKD2_k127_785807_1	86416.Clopa_2517	5.408e-39	156.0	2EC16@1|root,3360E@2|Bacteria,1UI87@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4373
HKD2_k127_785807_4	1295642.H839_08129	1.299e-12	70.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26,HTH_3
HKD2_k127_785807_2	1141106.CAIB01000160_gene1539	7.696e-25	112.0	COG3655@1|root,COG3655@2|Bacteria,1VKVP@1239|Firmicutes,4HRJ4@91061|Bacilli,4H03P@90964|Staphylococcaceae	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
HKD2_k127_785807_0	649639.Bcell_2753	2.039e-101	338.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HF0S@91061|Bacilli,1ZQ6N@1386|Bacillus	91061|Bacilli	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
HKD2_k127_7862871_5	1403313.AXBR01000025_gene4945	4.179e-63	219.0	2BVDP@1|root,32QTK@2|Bacteria,1V9E2@1239|Firmicutes,4HJ1S@91061|Bacilli,1ZFUF@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2521)	ybaK	-	-	-	-	-	-	-	-	-	-	-	DUF2521
HKD2_k127_7862871_2	1403313.AXBR01000025_gene4944	1.301e-107	354.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,1ZBJ8@1386|Bacillus	91061|Bacilli	M	n-acetylmuramoyl-L-alanine amidase	cwlD	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD2_k127_7862871_0	1211814.CAPG01000091_gene4224	5.679e-182	574.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4HAW4@91061|Bacilli,1ZC2E@1386|Bacillus	91061|Bacilli	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HKD2_k127_7862871_4	1403313.AXBR01000025_gene4942	8.475e-68	235.0	29HQ2@1|root,304MB@2|Bacteria,1V21Z@1239|Firmicutes,4HG8B@91061|Bacilli,1ZC8S@1386|Bacillus	91061|Bacilli	S	Spore gernimation protein	gerD	-	-	ko:K06294	-	-	-	-	ko00000	-	-	-	-
HKD2_k127_7862871_3	1403313.AXBR01000025_gene4941	1.371e-83	283.0	COG2194@1|root,COG2194@2|Bacteria,1UZ64@1239|Firmicutes,4HFDE@91061|Bacilli,1ZFN5@1386|Bacillus	91061|Bacilli	S	Involved in the activation of the KinB signaling pathway of sporulation	kbaA	GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K06349	-	-	-	-	ko00000	-	-	-	KbaA
HKD2_k127_7862871_1	1403313.AXBR01000025_gene4940	2.874e-122	396.0	COG0726@1|root,COG0726@2|Bacteria,1UZJN@1239|Firmicutes,4IPMR@91061|Bacilli,1ZBAU@1386|Bacillus	91061|Bacilli	G	xylanase chitin deacetylase	pdaB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_7862871_6	1034347.CAHJ01000086_gene1576	3.013e-26	109.0	2EIRB@1|root,33CGR@2|Bacteria,1VFHX@1239|Firmicutes,4HP39@91061|Bacilli,1ZJ0H@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7865367_7	1227360.C176_09697	2.882e-107	348.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,26DKT@186818|Planococcaceae	91061|Bacilli	O	Redoxin	ykuU	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
HKD2_k127_7865367_2	1403313.AXBR01000021_gene3255	1.205e-200	629.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,1ZC15@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate	hipO	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.47	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD2_k127_7865367_6	1403313.AXBR01000021_gene3256	4.657e-123	397.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,1ZBFG@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapH	-	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU14180	DapH_N,Hexapep
HKD2_k127_7865367_4	1403313.AXBR01000021_gene3257	1.935e-177	557.0	COG0583@1|root,COG0583@2|Bacteria,1TZ6U@1239|Firmicutes,4HB3Y@91061|Bacilli,1ZB8N@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ccpC	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_7865367_1	1403313.AXBR01000021_gene3260	3.545e-222	698.0	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	bmr3	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_7865367_8	1403313.AXBR01000021_gene3261	6.121e-73	247.0	COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli,1ZRSD@1386|Bacillus	91061|Bacilli	S	COG0517 FOG CBS domain	ykuL	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD2_k127_7865367_14	1307436.PBF_06496	3.519e-14	74.0	2CDFG@1|root,2ZRQY@2|Bacteria,1W6MM@1239|Firmicutes,4I24H@91061|Bacilli,1ZKSN@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_10
HKD2_k127_7865367_10	1403313.AXBR01000021_gene3262	6.625e-40	149.0	COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,1ZI15@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ykuJ	-	-	-	-	-	-	-	-	-	-	-	DUF1797
HKD2_k127_7865367_12	1034347.CAHJ01000011_gene2277	1.458e-24	104.0	COG0695@1|root,COG0695@2|Bacteria,1VK60@1239|Firmicutes,4I3VF@91061|Bacilli,1ZJE6@1386|Bacillus	91061|Bacilli	O	COG0695 Glutaredoxin and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
HKD2_k127_7865367_15	198467.NP92_01155	1.713e-12	70.0	2EI26@1|root,33BTM@2|Bacteria,1VQ3U@1239|Firmicutes,4HRAZ@91061|Bacilli,21X5V@150247|Anoxybacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7865367_3	1403313.AXBR01000021_gene3267	5.862e-191	602.0	COG2200@1|root,COG2200@2|Bacteria,1UADD@1239|Firmicutes,4HCNX@91061|Bacilli,1ZBWD@1386|Bacillus	91061|Bacilli	T	Diguanylate phosphodiesterase	ykuI	-	-	-	-	-	-	-	-	-	-	-	EAL,YkuI_C
HKD2_k127_7865367_0	1403313.AXBR01000021_gene3268	1.325e-256	804.0	COG0471@1|root,COG0471@2|Bacteria,1UI5K@1239|Firmicutes,4HC1Q@91061|Bacilli,1ZEGQ@1386|Bacillus	91061|Bacilli	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
HKD2_k127_7865367_13	868864.Dester_0089	1.129e-17	87.0	COG0239@1|root,COG0239@2|Bacteria,2G47X@200783|Aquificae	200783|Aquificae	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD2_k127_7865367_11	1403313.AXBR01000021_gene3270	9.138e-32	127.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,4HNI0@91061|Bacilli,1ZJ3M@1386|Bacillus	91061|Bacilli	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD2_k127_7865367_17	1294265.JCM21738_1787	5.384e-06	49.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD2_k127_7865367_16	1243664.CAVL020000025_gene1640	1.428e-06	55.0	29T6E@1|root,30ED5@2|Bacteria,1UCET@1239|Firmicutes,4INX6@91061|Bacilli,1ZP2G@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7865367_9	1403313.AXBR01000021_gene3272	1.085e-71	246.0	2ABH1@1|root,310Y3@2|Bacteria,1V4IK@1239|Firmicutes,4HI56@91061|Bacilli,1ZGD1@1386|Bacillus	91061|Bacilli	S	YkyB-like protein	ykyB	-	-	-	-	-	-	-	-	-	-	-	YkyB
HKD2_k127_7865367_5	1403313.AXBR01000021_gene3273	1.092e-158	505.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,4HCPT@91061|Bacilli,1ZAYA@1386|Bacillus	91061|Bacilli	T	Chemotaxis protein CheV	cheV	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
HKD2_k127_7866262_6	1121422.AUMW01000006_gene684	1.223e-52	188.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,261P1@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_7866262_8	1340434.AXVA01000016_gene701	1.504e-12	68.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7866262_7	1123009.AUID01000013_gene1753	2.993e-43	166.0	COG1633@1|root,COG1633@2|Bacteria,1VAXV@1239|Firmicutes,24KX7@186801|Clostridia	186801|Clostridia	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
HKD2_k127_7866262_5	997296.PB1_04950	2.921e-61	213.0	COG1146@1|root,COG1146@2|Bacteria,1VDZ3@1239|Firmicutes,4HMV6@91061|Bacilli,1ZKKJ@1386|Bacillus	91061|Bacilli	C	4Fe-4S ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HKD2_k127_7866262_0	997296.PB1_04955	1.827e-296	915.0	COG1053@1|root,COG1053@2|Bacteria,1V0YZ@1239|Firmicutes,4HFF5@91061|Bacilli,1ZE4A@1386|Bacillus	91061|Bacilli	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD2_k127_7866262_2	1132442.KB889752_gene1240	4.725e-256	793.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	yxeK	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_7866262_4	1132442.KB889752_gene1242	1.549e-119	385.0	COG0778@1|root,COG0778@2|Bacteria,1V49Q@1239|Firmicutes,4HHWF@91061|Bacilli,1ZFWJ@1386|Bacillus	91061|Bacilli	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD2_k127_7866262_1	1132442.KB889752_gene1241	3.445e-264	819.0	COG0477@1|root,COG0477@2|Bacteria,1UNMW@1239|Firmicutes,4HFCU@91061|Bacilli,1ZS2J@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_7866262_3	1132442.KB889752_gene1239	1.361e-127	410.0	COG0715@1|root,COG0715@2|Bacteria,1V9ZY@1239|Firmicutes,4HTB1@91061|Bacilli,1ZDC2@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
HKD2_k127_7882288_9	1340434.AXVA01000004_gene2639	3.656e-18	83.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBDW@91061|Bacilli,1ZM7Q@1386|Bacillus	91061|Bacilli	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD2_k127_7882288_7	1174504.AJTN02000193_gene4139	2.088e-82	275.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,1ZFK3@1386|Bacillus	91061|Bacilli	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HKD2_k127_7882288_10	665959.HMPREF1013_01801	1.377e-17	83.0	2AWIN@1|root,31NF9@2|Bacteria,1TV4F@1239|Firmicutes,4IINS@91061|Bacilli,1ZJ38@1386|Bacillus	91061|Bacilli	S	YyzF-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YyzF
HKD2_k127_7882288_2	1403313.AXBR01000028_gene5066	9.074e-181	573.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	yyxA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD2_k127_7882288_4	1403313.AXBR01000028_gene5067	7.152e-156	494.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,1ZASY@1386|Bacillus	91061|Bacilli	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	vicX	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
HKD2_k127_7882288_8	1347086.CCBA010000004_gene4499	1.276e-49	186.0	COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,1ZDGV@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yycI	-	-	-	-	-	-	-	-	-	-	-	YycI
HKD2_k127_7882288_5	1403313.AXBR01000028_gene5069	1.039e-145	473.0	COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yycH	-	-	-	-	-	-	-	-	-	-	-	YycH
HKD2_k127_7882288_0	1403313.AXBR01000028_gene5070	0.0	1003.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
HKD2_k127_7882288_6	1174504.AJTN02000193_gene4146	1.769e-144	458.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1ZAT8@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_7882288_13	1284352.AOIG01000026_gene423	2.36e-07	52.0	2DIDW@1|root,302XQ@2|Bacteria,1U4XH@1239|Firmicutes,4IBEG@91061|Bacilli,27456@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7882288_11	1134413.ANNK01000159_gene3626	4.975e-15	76.0	2A61F@1|root,30UTS@2|Bacteria,1UB8J@1239|Firmicutes,4IMMA@91061|Bacilli,1ZKEM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7882288_1	1403313.AXBR01000028_gene5074	8.287e-266	820.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,1ZBF8@1386|Bacillus	91061|Bacilli	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD2_k127_7882288_3	1174504.AJTN02000193_gene4149	7.082e-173	543.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD2_k127_788602_10	1294265.JCM21738_1282	3.564e-30	127.0	COG0526@1|root,COG0526@2|Bacteria,1VQ9F@1239|Firmicutes,4I8I8@91061|Bacilli,1ZJG1@1386|Bacillus	91061|Bacilli	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_788602_9	1231057.AMGD01000049_gene233	7.72e-43	160.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
HKD2_k127_788602_1	1294265.JCM21738_1280	1.989e-119	393.0	COG5002@1|root,COG5002@2|Bacteria,1TPPQ@1239|Firmicutes,4HCZW@91061|Bacilli,1ZF21@1386|Bacillus	91061|Bacilli	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_788602_3	935836.JAEL01000049_gene5372	6.308e-114	370.0	COG0745@1|root,COG0745@2|Bacteria,1TTBI@1239|Firmicutes,4HBQ0@91061|Bacilli,1ZEIK@1386|Bacillus	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_788602_4	1211814.CAPG01000071_gene3351	1.431e-107	353.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus	91061|Bacilli	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
HKD2_k127_788602_5	1294265.JCM21738_1290	5.207e-85	286.0	COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1ZAVN@1386|Bacillus	91061|Bacilli	OP	Belongs to the sulfur carrier protein TusA family	yrkF	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,TusA
HKD2_k127_788602_6	1034347.CAHJ01000054_gene137	3.255e-67	230.0	COG2210@1|root,COG2210@2|Bacteria,1V3UE@1239|Firmicutes,4HH93@91061|Bacilli,1ZQ9Q@1386|Bacillus	91061|Bacilli	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
HKD2_k127_788602_0	935836.JAEL01000049_gene5367	8.355e-195	613.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCWN@1386|Bacillus	91061|Bacilli	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD2_k127_788602_7	1121929.KB898663_gene854	8.483e-53	193.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,4I2ZH@91061|Bacilli,47220@74385|Gracilibacillus	1239|Firmicutes	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HKD2_k127_788602_11	1403313.AXBR01000018_gene3484	3.598e-14	73.0	COG0730@1|root,COG0730@2|Bacteria,1TRIE@1239|Firmicutes,4HARW@91061|Bacilli,1ZC6G@1386|Bacillus	91061|Bacilli	S	membrane transporter protein	yrkJ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD2_k127_788602_8	1174504.AJTN02000211_gene3603	1.118e-46	171.0	COG3439@1|root,COG3439@2|Bacteria,1VA5R@1239|Firmicutes,4HITT@91061|Bacilli,1ZH19@1386|Bacillus	91061|Bacilli	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
HKD2_k127_788602_2	1211814.CAPG01000056_gene2768	9.651e-119	390.0	COG3258@1|root,COG3258@2|Bacteria,1TSHS@1239|Firmicutes,4HBXB@91061|Bacilli,1ZN0Q@1386|Bacillus	91061|Bacilli	C	Cytochrome c	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD2_k127_788696_4	1403313.AXBR01000030_gene5371	3.138e-211	661.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
HKD2_k127_788696_6	1403313.AXBR01000030_gene5370	3.025e-180	567.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,1ZD4C@1386|Bacillus	91061|Bacilli	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD2_k127_788696_14	1403313.AXBR01000030_gene5364	4.486e-90	301.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,1ZDPJ@1386|Bacillus	91061|Bacilli	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HKD2_k127_788696_12	1403313.AXBR01000030_gene5363	1.424e-94	313.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD2_k127_788696_20	1403313.AXBR01000030_gene5362	2.22e-33	130.0	2EJ4H@1|root,33CVR@2|Bacteria,1VMIU@1239|Firmicutes,4HP24@91061|Bacilli,1ZJ5B@1386|Bacillus	91061|Bacilli	S	Peptide ABC transporter permease	yabK	-	-	-	-	-	-	-	-	-	-	-	DUF2757
HKD2_k127_788696_0	1403313.AXBR01000030_gene5360	0.0	1984.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus	91061|Bacilli	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HKD2_k127_788696_13	1403313.AXBR01000030_gene5359	4.65e-93	307.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,4HDIW@91061|Bacilli,1ZAXU@1386|Bacillus	91061|Bacilli	K	stage V sporulation protein	spoVT	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
HKD2_k127_788696_7	1403313.AXBR01000030_gene5358	3.461e-180	578.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	yabM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
HKD2_k127_788696_3	1403313.AXBR01000030_gene5357	2.647e-241	752.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus	91061|Bacilli	S	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
HKD2_k127_788696_19	279010.BL00511	5.345e-37	141.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,1ZHXN@1386|Bacillus	91061|Bacilli	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	yabO	-	-	-	-	-	-	-	-	-	-	-	S4
HKD2_k127_788696_17	1403313.AXBR01000030_gene5355	1.505e-57	200.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,4HPDE@91061|Bacilli,1ZGYU@1386|Bacillus	91061|Bacilli	S	Sporulation protein YabP	yabP	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	YabP
HKD2_k127_788696_15	1403313.AXBR01000030_gene5354	3.416e-71	246.0	2BYDV@1|root,32RAH@2|Bacteria,1V91M@1239|Firmicutes,4HIIQ@91061|Bacilli,1ZH7H@1386|Bacillus	91061|Bacilli	S	spore cortex biosynthesis protein	yabQ	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
HKD2_k127_788696_18	1403313.AXBR01000030_gene5353	1.205e-39	150.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,1ZIBZ@1386|Bacillus	91061|Bacilli	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
HKD2_k127_788696_16	1211814.CAPG01000094_gene4305	2.967e-67	231.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,1ZG7S@1386|Bacillus	91061|Bacilli	J	RNA binding protein (contains ribosomal protein S1 domain)	yabR	-	-	ko:K07571	-	-	-	-	ko00000	-	-	-	S1
HKD2_k127_788696_1	1403313.AXBR01000030_gene5351	0.0	1368.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus	91061|Bacilli	KT	stage II sporulation protein E	spoIIE	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
HKD2_k127_788696_11	171693.BN988_03519	6.295e-95	316.0	COG2304@1|root,COG2304@2|Bacteria,1U1SJ@1239|Firmicutes,4HD70@91061|Bacilli,23IRQ@182709|Oceanobacillus	91061|Bacilli	S	von Willebrand factor type A domain	yabS	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
HKD2_k127_788696_8	1403313.AXBR01000030_gene5349	1.446e-134	435.0	COG0515@1|root,COG0515@2|Bacteria,1TSNS@1239|Firmicutes,4HBDI@91061|Bacilli,1ZBVA@1386|Bacillus	91061|Bacilli	KLT	serine threonine protein kinase	yabT	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HKD2_k127_788696_5	1403313.AXBR01000030_gene5348	3.476e-204	647.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,1ZBFQ@1386|Bacillus	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HKD2_k127_788696_10	1174504.AJTN02000203_gene2758	2.832e-100	329.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,1ZB7B@1386|Bacillus	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
HKD2_k127_788696_2	1174504.AJTN02000203_gene2757	0.0	1090.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZBEU@1386|Bacillus	91061|Bacilli	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD2_k127_788696_9	1403313.AXBR01000030_gene5345	1.005e-125	404.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HKD2_k127_7889053_22	1403313.AXBR01000010_gene1078	4.048e-12	67.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,4HA51@91061|Bacilli,1ZQ9I@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	apl	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	SNARE_assoc
HKD2_k127_7889053_23	1347086.CCBA010000043_gene2528	1.711e-08	55.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,4HA51@91061|Bacilli,1ZQ9I@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	apl	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	SNARE_assoc
HKD2_k127_7889053_20	1321778.HMPREF1982_02882	1.045e-27	114.0	COG2350@1|root,COG2350@2|Bacteria,1VFY8@1239|Firmicutes,24NN0@186801|Clostridia	186801|Clostridia	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD2_k127_7889053_11	871963.Desdi_1635	5.326e-84	286.0	COG0596@1|root,COG0596@2|Bacteria,1V85M@1239|Firmicutes,24SMS@186801|Clostridia	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD2_k127_7889053_24	426716.JOAJ01000001_gene643	3.481e-07	59.0	COG1309@1|root,COG1309@2|Bacteria,2IFRU@201174|Actinobacteria,4G0BV@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_7889053_9	1408303.JNJJ01000085_gene2622	7.936e-95	314.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,4HA51@91061|Bacilli,1ZQ9I@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	apl	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	SNARE_assoc
HKD2_k127_7889053_18	935837.JAEK01000004_gene4585	8.35e-37	141.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHUB@1386|Bacillus	91061|Bacilli	K	'Cold-shock' DNA-binding domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_7889053_12	1174504.AJTN02000253_gene2353	5.379e-69	237.0	2AD85@1|root,312X5@2|Bacteria,1V735@1239|Firmicutes,4HIXA@91061|Bacilli,1ZGBJ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7889053_13	1403313.AXBR01000023_gene2518	2.15e-68	233.0	COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZMQH@1386|Bacillus	91061|Bacilli	P	ArsC family	spxA	-	-	ko:K16509	-	-	-	-	ko00000	-	-	-	ArsC
HKD2_k127_7889053_2	1403313.AXBR01000023_gene2519	4.015e-215	676.0	COG0642@1|root,COG2205@2|Bacteria,1TZXJ@1239|Firmicutes,4HDAI@91061|Bacilli,1ZCPT@1386|Bacillus	91061|Bacilli	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	phoR_2	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_7889053_8	1462526.BN990_00404	1.448e-96	320.0	COG0745@1|root,COG0745@2|Bacteria,1UX1V@1239|Firmicutes,4HD2J@91061|Bacilli	91061|Bacilli	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_7889053_1	1403313.AXBR01000023_gene2601	7.473e-285	879.0	COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,4HBAW@91061|Bacilli,1ZAT5@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein R	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
HKD2_k127_7889053_21	1403313.AXBR01000023_gene2608	1.377e-21	98.0	2BAGI@1|root,323X4@2|Bacteria,1UARE@1239|Firmicutes,4IM44@91061|Bacilli,1ZJ3I@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3889
HKD2_k127_7889053_6	1403313.AXBR01000023_gene2609	6.234e-128	419.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZDXZ@1386|Bacillus	91061|Bacilli	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Cu_amine_oxidN1,Peptidase_M14
HKD2_k127_7889053_19	1403313.AXBR01000023_gene2610	4.183e-33	129.0	2E2U4@1|root,32XW8@2|Bacteria,1VAT9@1239|Firmicutes,4HN53@91061|Bacilli,1ZHZK@1386|Bacillus	91061|Bacilli	S	YhdB-like protein	yhdB	-	-	-	-	-	-	-	-	-	-	-	YhdB
HKD2_k127_7889053_0	1403313.AXBR01000023_gene2613	1.103e-290	900.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,1ZBEM@1386|Bacillus	91061|Bacilli	G	Phosphoglucomutase	pgcA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD2_k127_7889053_15	665959.HMPREF1013_00997	1.311e-66	229.0	COG1495@1|root,COG1495@2|Bacteria,1VAYZ@1239|Firmicutes,4IRN5@91061|Bacilli,1ZRVY@1386|Bacillus	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
HKD2_k127_7889053_16	935836.JAEL01000075_gene3034	1.611e-60	212.0	COG0526@1|root,COG0526@2|Bacteria,1V3YC@1239|Firmicutes,4HJ8N@91061|Bacilli,1ZH2W@1386|Bacillus	91061|Bacilli	CO	Thioredoxin	bdbA	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD2_k127_7889053_17	1403313.AXBR01000023_gene2617	5.788e-38	146.0	29RAQ@1|root,30CCF@2|Bacteria,1U9MH@1239|Firmicutes,4IJSY@91061|Bacilli,1ZG4U@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5365)	yhcU	-	-	-	-	-	-	-	-	-	-	-	DUF5365
HKD2_k127_7889053_5	1403313.AXBR01000023_gene2618	1.757e-134	434.0	COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,1ZDMG@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD2_k127_7889053_7	1403313.AXBR01000023_gene2622	8.771e-103	338.0	COG1392@1|root,COG1392@2|Bacteria,1V2QG@1239|Firmicutes,4IRDK@91061|Bacilli,1ZRTN@1386|Bacillus	91061|Bacilli	P	COG1392 Phosphate transport regulator (distant homolog of PhoU)	ykaA	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HKD2_k127_7889053_4	1403313.AXBR01000023_gene2623	7.748e-178	560.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,1ZBFE@1386|Bacillus	91061|Bacilli	P	phosphate transporter	pit	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD2_k127_7889053_3	1403313.AXBR01000023_gene2626	6.522e-195	616.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,1ZBQE@1386|Bacillus	91061|Bacilli	E	Belongs to the AlaDH PNT family	ald	GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD2_k127_7889053_10	1403313.AXBR01000023_gene2631	1.974e-89	298.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,1ZFWT@1386|Bacillus	91061|Bacilli	L	Belongs to the DNA glycosylase MPG family	yxlJ	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD2_k127_7889053_14	471223.GWCH70_1607	4.646e-67	235.0	2FF2F@1|root,3470R@2|Bacteria,1UKKY@1239|Firmicutes,4ITJG@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7910326_7	1347087.CBYO010000007_gene1085	5.783e-81	276.0	COG0438@1|root,COG0438@2|Bacteria,1TT3F@1239|Firmicutes,4HEJR@91061|Bacilli	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_7910326_0	1347087.CBYO010000007_gene1086	2.313e-252	797.0	COG4641@1|root,COG4641@2|Bacteria,1TQDC@1239|Firmicutes,4HD50@91061|Bacilli	91061|Bacilli	M	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2
HKD2_k127_7910326_8	1174504.AJTN02000153_gene996	6.414e-30	125.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMDE@91061|Bacilli,1ZI6Q@1386|Bacillus	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD2_k127_7910326_2	471223.GWCH70_0603	2.566e-176	560.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1WFAK@129337|Geobacillus	91061|Bacilli	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_7910326_3	1403313.AXBR01000008_gene706	3.069e-172	560.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZAZE@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FlgD_ig,PPC,Peptidase_S8,SLH
HKD2_k127_7910326_6	1403313.AXBR01000008_gene712	2.046e-121	392.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1ZBFK@1386|Bacillus	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
HKD2_k127_7910326_5	1403313.AXBR01000008_gene713	2.489e-145	464.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus	91061|Bacilli	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HKD2_k127_7910326_1	1403313.AXBR01000008_gene714	1.816e-176	557.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1ZBHB@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_7910326_4	1403313.AXBR01000008_gene715	3.104e-154	491.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,1ZBP3@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_7910326_9	1340434.AXVA01000010_gene5484	8.204e-09	57.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_7932709_1	1403313.AXBR01000008_gene733	6.907e-238	743.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
HKD2_k127_7932709_3	1123359.AUIQ01000025_gene46	3.444e-68	235.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,4AZXA@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HKD2_k127_7932709_0	1403313.AXBR01000008_gene731	0.0	1288.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
HKD2_k127_7932709_2	1403313.AXBR01000008_gene730	2.346e-78	263.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1ZG82@1386|Bacillus	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HKD2_k127_7932709_4	1347086.CCBA010000023_gene2173	2.843e-40	153.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4084,EAL,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PilZ
HKD2_k127_8005369_4	1174504.AJTN02000241_gene4338	3.846e-20	96.0	COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_9
HKD2_k127_8005369_1	1403313.AXBR01000005_gene2019	1.926e-158	502.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD2_k127_8005369_2	1174504.AJTN02000241_gene4335	4.968e-30	119.0	2CGYI@1|root,32YUY@2|Bacteria,1VGI2@1239|Firmicutes,4HPBN@91061|Bacilli,1ZJ06@1386|Bacillus	91061|Bacilli	S	Cold-inducible protein YdjO	-	-	-	-	-	-	-	-	-	-	-	-	YdjO
HKD2_k127_8005369_3	1403313.AXBR01000005_gene2021	2.446e-29	118.0	2BRCU@1|root,32KBH@2|Bacteria,1UAZC@1239|Firmicutes,4IMCA@91061|Bacilli,1ZJSM@1386|Bacillus	91061|Bacilli	S	Cold-inducible protein YdjO	-	-	-	-	-	-	-	-	-	-	-	-	YdjO
HKD2_k127_8005369_0	1403313.AXBR01000005_gene2022	0.0	1047.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus	91061|Bacilli	L	DNA helicase	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HKD2_k127_805442_3	1405.DJ92_2655	3.101e-09	57.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus	91061|Bacilli	KT	stage II sporulation protein E	spoIIE	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
HKD2_k127_805442_0	574376.BAMA_12160	7.772e-191	606.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,1ZBFQ@1386|Bacillus	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HKD2_k127_805442_1	315749.Bcer98_0059	1.071e-98	323.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,1ZB7B@1386|Bacillus	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
HKD2_k127_805442_2	574376.BAMA_12170	1.539e-13	71.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZBEU@1386|Bacillus	91061|Bacilli	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD2_k127_8061409_2	1384057.CD33_11715	1.533e-46	171.0	2C593@1|root,2Z84R@2|Bacteria,1U546@1239|Firmicutes,4HEHB@91061|Bacilli	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8061409_3	1340434.AXVA01000010_gene5484	2.34e-06	50.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8061409_0	1384057.CD33_11710	1.268e-282	882.0	2C593@1|root,2Z84R@2|Bacteria,1U546@1239|Firmicutes,4HEHB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8061409_1	1185653.A1A1_09911	2.67e-208	653.0	COG0026@1|root,COG0026@2|Bacteria,1TTDR@1239|Firmicutes,4HDHY@91061|Bacilli	91061|Bacilli	F	Carboxylate--amine ligase	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
HKD2_k127_806238_1	1132442.KB889752_gene3555	6.11e-35	133.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus	91061|Bacilli	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD2_k127_806238_0	1403313.AXBR01000007_gene290	0.0	1078.0	COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus	91061|Bacilli	KL	COG1199 Rad3-related DNA helicases	ypvA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
HKD2_k127_8064023_4	935836.JAEL01000102_gene1834	7.86e-17	83.0	COG0741@1|root,COG0741@2|Bacteria,1VD4A@1239|Firmicutes,4HN7R@91061|Bacilli,1ZDE7@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yocA	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
HKD2_k127_8064023_0	1002809.SSIL_2386	1.458e-297	927.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,26GT3@186818|Planococcaceae	91061|Bacilli	M	Transglycosylase	pbp2A	-	2.4.1.129,3.4.16.4	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD2_k127_8064023_1	1340434.AXVA01000014_gene481	3.011e-292	902.0	COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus	91061|Bacilli	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
HKD2_k127_8064023_2	796606.BMMGA3_10185	2.556e-94	312.0	COG2928@1|root,COG2928@2|Bacteria,1V5YU@1239|Firmicutes,4HI5E@91061|Bacilli,1ZEB2@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
HKD2_k127_8064023_3	1403313.AXBR01000013_gene1544	5.594e-48	174.0	COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus	91061|Bacilli	P	Belongs to the alkaline phosphatase family	phoB	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,Cu_amine_oxidN1
HKD2_k127_8076598_5	1403313.AXBR01000013_gene1298	1.263e-136	445.0	COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,1ZAQG@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	minJ	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
HKD2_k127_8076598_1	1403313.AXBR01000013_gene1297	1.211e-220	694.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpB	GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
HKD2_k127_8076598_3	1403313.AXBR01000013_gene1296	6.522e-150	484.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus	91061|Bacilli	D	peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD2_k127_8076598_6	1403313.AXBR01000013_gene1295	1.3e-136	440.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus	91061|Bacilli	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD2_k127_8076598_7	265729.GS18_0213655	3.818e-106	348.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,1ZCAE@1386|Bacillus	91061|Bacilli	D	cell division ATP-binding protein FtsE	ftsE	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD2_k127_8076598_12	997296.PB1_09337	5.464e-36	141.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,1ZITU@1386|Bacillus	91061|Bacilli	C	COG2010 Cytochrome c, mono- and diheme variants	cccB	-	-	ko:K12263,ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
HKD2_k127_8076598_4	1403313.AXBR01000013_gene1292	4.668e-144	460.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,1ZC5M@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD2_k127_8076598_2	1174504.AJTN02000254_gene2269	1.554e-190	598.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,1ZB5N@1386|Bacillus	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD2_k127_8076598_0	1403313.AXBR01000013_gene1290	0.0	1448.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD2_k127_8076598_11	1211814.CAPG01000060_gene2899	1.833e-47	171.0	COG1396@1|root,COG1396@2|Bacteria,1VAXE@1239|Firmicutes,4HKHB@91061|Bacilli,1ZHZH@1386|Bacillus	91061|Bacilli	K	transcriptional	sinR	GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0048519,GO:0050789,GO:0060255,GO:0065007	-	ko:K19449	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,SinI
HKD2_k127_8076598_9	1174504.AJTN02000254_gene2279	1.334e-85	286.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,1ZFW8@1386|Bacillus	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HKD2_k127_8076598_14	1234664.AMRO01000028_gene1455	3.029e-09	62.0	2DN2R@1|root,32V7F@2|Bacteria,1VBH1@1239|Firmicutes,4HN5P@91061|Bacilli,1WHX3@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8076598_13	1294265.JCM21738_722	2.632e-27	115.0	2E69G@1|root,330XF@2|Bacteria,1VEKH@1239|Firmicutes,4HNWI@91061|Bacilli,1ZIW8@1386|Bacillus	91061|Bacilli	S	bacterial-type flagellum organization	fliT	-	-	ko:K02423	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
HKD2_k127_8076598_10	1174504.AJTN02000254_gene2282	6.014e-57	200.0	COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,4HIN5@91061|Bacilli,1ZH26@1386|Bacillus	91061|Bacilli	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
HKD2_k127_8076598_8	1174504.AJTN02000254_gene2283	1.687e-90	305.0	COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,4H9TN@91061|Bacilli,1ZCIG@1386|Bacillus	91061|Bacilli	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
HKD2_k127_8088974_2	1220589.CD32_12300	1.303e-87	293.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,3IXXA@400634|Lysinibacillus	91061|Bacilli	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD2_k127_8088974_0	1243664.CAVL020000027_gene777	7.488e-271	837.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,4HEYP@91061|Bacilli,1ZM4F@1386|Bacillus	91061|Bacilli	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
HKD2_k127_8088974_4	1121121.KB894328_gene2273	3.593e-47	180.0	COG3209@1|root,COG3209@2|Bacteria,1UNNH@1239|Firmicutes,4IUIU@91061|Bacilli,277N5@186822|Paenibacillaceae	91061|Bacilli	M	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
HKD2_k127_8088974_5	1122919.KB905603_gene4690	0.0004509	46.0	COG0840@1|root,COG0840@2|Bacteria,1UWQU@1239|Firmicutes,4IBKV@91061|Bacilli,26YWK@186822|Paenibacillaceae	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
HKD2_k127_8088974_1	666686.B1NLA3E_02695	7.878e-90	302.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HK7U@91061|Bacilli,1ZDH4@1386|Bacillus	91061|Bacilli	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
HKD2_k127_8088974_3	1117379.BABA_14927	9.548e-72	244.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4HH6X@91061|Bacilli,1ZDE1@1386|Bacillus	91061|Bacilli	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HKD2_k127_8094483_3	1132442.KB889752_gene1936	7.5e-127	408.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,4HC6V@91061|Bacilli,1ZDBU@1386|Bacillus	91061|Bacilli	H	Precorrin-6x reductase CbiJ/CobK	cbiJ	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
HKD2_k127_8094483_2	1132442.KB889752_gene1935	1.457e-130	417.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,4HCSR@91061|Bacilli,1ZDQ4@1386|Bacillus	91061|Bacilli	H	Precorrin-8X methylmutase	cbiC	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
HKD2_k127_8094483_1	1211814.CAPG01000027_gene998	1.154e-175	557.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,4HBDG@91061|Bacilli,1ZC23@1386|Bacillus	91061|Bacilli	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
HKD2_k127_8094483_0	1132442.KB889752_gene1933	1.603e-239	743.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,4HAP3@91061|Bacilli,1ZEWB@1386|Bacillus	91061|Bacilli	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiET	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_18,PCMT,TP_methylase
HKD2_k127_8094483_4	1134413.ANNK01000091_gene24	3.75e-116	377.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,4HB4V@91061|Bacilli,1ZEKA@1386|Bacillus	91061|Bacilli	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiL	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HKD2_k127_8099175_1	180332.JTGN01000003_gene2210	7.066e-33	135.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
HKD2_k127_8099175_0	160799.PBOR_25385	2.712e-185	585.0	COG5520@1|root,COG5520@2|Bacteria,1URVQ@1239|Firmicutes,4HE4Z@91061|Bacilli,26RD8@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD2_k127_8110181_1	634956.Geoth_3749	7.17e-114	376.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,4HB18@91061|Bacilli,1WFR4@129337|Geobacillus	91061|Bacilli	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HKD2_k127_8110181_2	697284.ERIC2_c03670	9.006e-19	88.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,26T4B@186822|Paenibacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HKD2_k127_8110181_0	1131730.BAVI_17702	1.451e-194	617.0	COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus	91061|Bacilli	K	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2
HKD2_k127_8147455_2	1034347.CAHJ01000009_gene1859	4.558e-19	89.0	2EH6H@1|root,33AYD@2|Bacteria,1VK79@1239|Firmicutes,4HRGE@91061|Bacilli,1ZIYP@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8147455_0	1340434.AXVA01000015_gene660	0.0	1078.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus	91061|Bacilli	M	Belongs to the LTA synthase family	yflE	GO:0005575,GO:0005576	2.7.8.20	ko:K19005	ko00561,ko01100,map00561,map01100	-	R05081,R10849	RC00017	ko00000,ko00001,ko01000	-	-	-	Sulfatase
HKD2_k127_8147455_1	1131730.BAVI_08976	2.798e-199	637.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus	91061|Bacilli	KL	DEAD_2	uvrB3	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
HKD2_k127_8148202_0	198094.BA_5513	6.2e-322	1008.0	COG0627@1|root,COG0627@2|Bacteria,1V28D@1239|Firmicutes,4HNGJ@91061|Bacilli,1ZEGT@1386|Bacillus	91061|Bacilli	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N,Y_Y_Y
HKD2_k127_8148202_1	1347087.CBYO010000007_gene1085	6.433e-209	658.0	COG0438@1|root,COG0438@2|Bacteria,1TT3F@1239|Firmicutes,4HEJR@91061|Bacilli	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_8156396_3	1403313.AXBR01000006_gene97	3.847e-88	296.0	COG1999@1|root,COG1999@2|Bacteria,1V03J@1239|Firmicutes,4HET3@91061|Bacilli,1ZFJQ@1386|Bacillus	91061|Bacilli	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	ypmQ	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD2_k127_8156396_5	1403313.AXBR01000006_gene98	2.922e-23	100.0	COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,1ZCJP@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD2_k127_8156396_2	1403313.AXBR01000006_gene99	3.44e-110	361.0	COG0805@1|root,COG0805@2|Bacteria,1V372@1239|Firmicutes,4HFT0@91061|Bacilli,1ZQXF@1386|Bacillus	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD2_k127_8156396_6	997296.PB1_13434	7.099e-21	93.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,1ZIUG@1386|Bacillus	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HKD2_k127_8156396_0	1403313.AXBR01000006_gene101	3.857e-234	728.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,1ZBM0@1386|Bacillus	91061|Bacilli	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
HKD2_k127_8156396_4	1403313.AXBR01000006_gene102	8.283e-75	254.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1ZG71@1386|Bacillus	91061|Bacilli	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	dfrA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
HKD2_k127_8156396_1	1403313.AXBR01000006_gene103	8.75e-161	507.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,1ZAUT@1386|Bacillus	91061|Bacilli	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HKD2_k127_8156396_7	1174504.AJTN02000222_gene1405	1.963e-06	51.0	29PIZ@1|root,30AH4@2|Bacteria,1VJKE@1239|Firmicutes,4HI1K@91061|Bacilli,1ZDJM@1386|Bacillus	91061|Bacilli	-	-	-	-	3.4.24.89	ko:K20109	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ATLF
HKD2_k127_8174013_0	218284.CCDN010000006_gene3560	8.454e-136	439.0	COG0477@1|root,COG2814@2|Bacteria,1TSS7@1239|Firmicutes,4HC6A@91061|Bacilli,1ZBCF@1386|Bacillus	91061|Bacilli	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_8186949_10	1294265.JCM21738_1618	1.083e-32	132.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4HD4Q@91061|Bacilli,1ZDNG@1386|Bacillus	91061|Bacilli	T	signal transduction protein containing EAL and modified HD-GYP domains	yuxH	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
HKD2_k127_8186949_12	1121396.KB892903_gene4239	1.154e-10	64.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2WK3V@28221|Deltaproteobacteria,2MIQC@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
HKD2_k127_8186949_5	796606.BMMGA3_08060	1.259e-106	347.0	COG0288@1|root,COG0288@2|Bacteria,1V0TA@1239|Firmicutes,4HB9V@91061|Bacilli	91061|Bacilli	P	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD2_k127_8186949_8	1499680.CCFE01000016_gene1143	2.017e-44	163.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,1ZH0F@1386|Bacillus	91061|Bacilli	K	COG2002 Regulators of stationary sporulation gene expression	abrB	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
HKD2_k127_8186949_3	1340434.AXVA01000022_gene4019	1.37e-142	457.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD2_k127_8186949_2	997296.PB1_04530	1.162e-147	481.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,4HC66@91061|Bacilli,1ZATU@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD2_k127_8186949_6	997296.PB1_04535	1.239e-100	333.0	COG0745@1|root,COG0745@2|Bacteria,1TX0Q@1239|Firmicutes,4HEF8@91061|Bacilli,1ZBAA@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_8186949_7	997296.PB1_04540	5.432e-57	207.0	COG4200@1|root,COG4200@2|Bacteria,1TRGZ@1239|Firmicutes,4HK0F@91061|Bacilli,1ZR5E@1386|Bacillus	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
HKD2_k127_8186949_9	1501230.ET33_31915	5.106e-35	143.0	COG4200@1|root,COG4200@2|Bacteria,1V492@1239|Firmicutes,4HCDB@91061|Bacilli,26V4I@186822|Paenibacillaceae	91061|Bacilli	S	Permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
HKD2_k127_8186949_4	997296.PB1_04550	2.525e-111	367.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,1ZB4N@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K20459	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran,DUF4162
HKD2_k127_8186949_1	1211035.CD30_16015	6.228e-169	533.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HBX5@91061|Bacilli,3IWSD@400634|Lysinibacillus	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD2_k127_8186949_0	1196323.ALKF01000144_gene1299	2.814e-178	560.0	COG0535@1|root,COG0535@2|Bacteria,1UPAB@1239|Firmicutes,4HEEZ@91061|Bacilli,26QNG@186822|Paenibacillaceae	91061|Bacilli	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
HKD2_k127_8186949_11	946235.CAER01000060_gene3262	1.963e-26	110.0	2CH62@1|root,32S5C@2|Bacteria,1VD6E@1239|Firmicutes,4HKZ3@91061|Bacilli,23M30@182709|Oceanobacillus	91061|Bacilli	-	-	yoaF	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8190881_3	1461580.CCAS010000042_gene3328	1.69e-13	69.0	COG0409@1|root,COG0409@2|Bacteria,1TPM7@1239|Firmicutes,4HDBJ@91061|Bacilli,1ZE8Y@1386|Bacillus	91061|Bacilli	O	Hydrogenase isoenzymes formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
HKD2_k127_8190881_1	1461580.CCAS010000042_gene3329	1.599e-171	543.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,4HB74@91061|Bacilli	91061|Bacilli	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
HKD2_k127_8190881_0	1033734.CAET01000067_gene2118	1.996e-280	876.0	COG0367@1|root,COG0367@2|Bacteria,1TR1K@1239|Firmicutes,4HD77@91061|Bacilli,1ZEFK@1386|Bacillus	91061|Bacilli	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD2_k127_8190881_4	666686.B1NLA3E_04485	4.05e-08	56.0	COG1493@1|root,COG1493@2|Bacteria,1V4IV@1239|Firmicutes,4HGBQ@91061|Bacilli,1ZCAB@1386|Bacillus	91061|Bacilli	T	Serine kinase of the HPr protein, regulates carbohydrate metabolism	hprK3	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Hpr_kinase_C
HKD2_k127_8197033_1	1294265.JCM21738_452	5.13e-199	629.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,4HCST@91061|Bacilli,1ZCPN@1386|Bacillus	91061|Bacilli	T	Sigma-54 interaction domain	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD2_k127_8197033_0	1034347.CAHJ01000015_gene3170	8.69e-254	800.0	COG4191@1|root,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,4HDJQ@91061|Bacilli,1ZC7F@1386|Bacillus	91061|Bacilli	T	GAF domain	cckA	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
HKD2_k127_8199889_4	1403313.AXBR01000017_gene3869	1.057e-76	262.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HK1U@91061|Bacilli,1ZR6M@1386|Bacillus	91061|Bacilli	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD2_k127_8199889_7	1385514.N782_03495	2.969e-08	55.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8199889_3	1403313.AXBR01000017_gene3868	8.81e-90	300.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4HJZM@91061|Bacilli,1ZFFU@1386|Bacillus	91061|Bacilli	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD2_k127_8199889_1	1403313.AXBR01000017_gene3867	6.276e-153	486.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,1ZBIX@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	lysR3	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_8199889_0	1227360.C176_11459	4.447e-195	613.0	COG1618@1|root,COG1618@2|Bacteria,1UHSS@1239|Firmicutes,4IS8E@91061|Bacilli	91061|Bacilli	F	nucleotide phosphatase activity, acting on free nucleotides	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8199889_5	946235.CAER01000060_gene3280	8.741e-36	141.0	COG1846@1|root,COG1846@2|Bacteria,1VBQ1@1239|Firmicutes,4HMXC@91061|Bacilli,23KVW@182709|Oceanobacillus	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD2_k127_8199889_2	1403313.AXBR01000027_gene5285	8.65e-140	455.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_8199889_6	1403313.AXBR01000027_gene5285	4.356e-29	118.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD2_k127_8220415_2	1131730.BAVI_14384	3.163e-34	132.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HA1X@91061|Bacilli,1ZCDN@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD2_k127_8220415_1	1117379.BABA_18442	9.235e-83	279.0	2DZZQ@1|root,32VP7@2|Bacteria,1VCZ5@1239|Firmicutes,4HN4F@91061|Bacilli,1ZC7H@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8220415_0	1403313.AXBR01000023_gene2359	1.93e-146	467.0	COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZAS0@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	yhxC	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD2_k127_8225897_1	666686.B1NLA3E_19270	2.508e-166	527.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1ZCXW@1386|Bacillus	91061|Bacilli	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
HKD2_k127_8225897_0	1499680.CCFE01000011_gene479	4.304e-188	591.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD2_k127_8225897_2	1403313.AXBR01000013_gene1337	1.028e-150	484.0	COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,1ZBYA@1386|Bacillus	91061|Bacilli	K	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain	cggR	-	-	ko:K05311	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
HKD2_k127_8225897_4	1403313.AXBR01000013_gene1336	1.213e-22	99.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	XAC3035	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06191	-	-	-	-	ko00000	-	-	-	DUF836,Glutaredoxin
HKD2_k127_8225897_3	1403313.AXBR01000013_gene1335	9.933e-131	422.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,1ZBKU@1386|Bacillus	91061|Bacilli	K	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD2_k127_8235651_0	1305836.AXVE01000011_gene1140	6.983e-112	369.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26CYX@186818|Planococcaceae	91061|Bacilli	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_9
HKD2_k127_8235651_1	866895.HBHAL_5018	2.069e-38	152.0	2B2QS@1|root,31VAP@2|Bacteria,1V7HH@1239|Firmicutes,4HJ7I@91061|Bacilli,3NF8Q@45667|Halobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8235651_2	1134413.ANNK01000002_gene2944	8.454e-24	100.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,4HD5Z@91061|Bacilli,1ZBHK@1386|Bacillus	91061|Bacilli	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
HKD2_k127_8262121_3	1403313.AXBR01000021_gene3274	8.287e-127	412.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus	91061|Bacilli	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD2_k127_8262121_1	1403313.AXBR01000021_gene3275	1.208e-190	601.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus	91061|Bacilli	E	Aminotransferase	patA	-	-	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R04467	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_8262121_2	1403313.AXBR01000021_gene3277	8.253e-136	437.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,1ZBSG@1386|Bacillus	91061|Bacilli	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	glxR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
HKD2_k127_8262121_4	1403313.AXBR01000021_gene3278	2.255e-126	408.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,1ZCSW@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD2_k127_8262121_0	1403313.AXBR01000021_gene3279	7.054e-230	724.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HKD2_k127_8262121_6	1174504.AJTN02000234_gene3184	1.838e-36	139.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,1ZHX7@1386|Bacillus	91061|Bacilli	G	phosphocarrier protein HPr	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HKD2_k127_8262121_5	1403313.AXBR01000021_gene3283	1.565e-103	344.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,1ZFIZ@1386|Bacillus	91061|Bacilli	L	Staphylococcal nuclease homologues	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
HKD2_k127_8262121_8	1403313.AXBR01000022_gene2710	1.235e-19	89.0	2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes,4HR2E@91061|Bacilli,1ZIUC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8262121_7	1403313.AXBR01000022_gene2711	5.466e-29	117.0	COG4873@1|root,COG4873@2|Bacteria,1VF7M@1239|Firmicutes,4HPMH@91061|Bacilli,1ZIXH@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ykvS	-	-	-	-	-	-	-	-	-	-	-	DUF2187
HKD2_k127_8262624_5	1403313.AXBR01000007_gene388	8.596e-06	49.0	COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,1ZG8Q@1386|Bacillus	91061|Bacilli	M	Lysin motif	ypbE	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD2_k127_8262624_0	1403313.AXBR01000007_gene390	1.979e-203	644.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus	91061|Bacilli	L	DNA helicase	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
HKD2_k127_8262624_2	1403313.AXBR01000007_gene391	1.052e-108	362.0	COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ypbB	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_40,RQC
HKD2_k127_8262624_3	1347369.CCAD010000050_gene325	1.072e-44	164.0	COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,1ZHTS@1386|Bacillus	91061|Bacilli	C	Ferredoxin	fer	GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
HKD2_k127_8262624_4	1403313.AXBR01000007_gene394	4.411e-25	105.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,1ZG7K@1386|Bacillus	91061|Bacilli	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
HKD2_k127_8262624_1	1403313.AXBR01000007_gene399	5.645e-111	362.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
HKD2_k127_8289811_2	1403313.AXBR01000025_gene4948	1.969e-42	156.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,1ZG6R@1386|Bacillus	91061|Bacilli	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HKD2_k127_8289811_3	1408303.JNJJ01000134_gene1959	0.0001273	45.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	sip	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HKD2_k127_8289811_0	1145276.T479_02140	7.34e-186	585.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3IYED@400634|Lysinibacillus	91061|Bacilli	E	Zinc-binding dehydrogenase	adh	-	1.1.1.1	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_8289811_1	1121024.AUCD01000009_gene2038	2.362e-169	546.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,27FHV@186828|Carnobacteriaceae	91061|Bacilli	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
HKD2_k127_8296131_0	1347369.CCAD010000045_gene528	1.906e-101	338.0	COG1595@1|root,COG1595@2|Bacteria,1UZM5@1239|Firmicutes,4HEK0@91061|Bacilli,1ZEV7@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_8311720_4	1536770.R50345_04965	2.234e-52	189.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4HCGH@91061|Bacilli,26WDN@186822|Paenibacillaceae	91061|Bacilli	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
HKD2_k127_8311720_1	1536775.H70737_05155	1.32e-144	467.0	COG1940@1|root,COG1940@2|Bacteria,1UWJH@1239|Firmicutes,4I34W@91061|Bacilli,26VAW@186822|Paenibacillaceae	91061|Bacilli	GK	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ROK
HKD2_k127_8311720_2	1536775.H70737_05160	4.306e-98	325.0	COG0363@1|root,COG0363@2|Bacteria,1V3C0@1239|Firmicutes,4HGQJ@91061|Bacilli,26V8W@186822|Paenibacillaceae	91061|Bacilli	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosamine_iso
HKD2_k127_8311720_3	985665.HPL003_21845	1.722e-92	312.0	COG1940@1|root,COG1940@2|Bacteria,1V3RA@1239|Firmicutes,4HHUE@91061|Bacilli,26VP0@186822|Paenibacillaceae	91061|Bacilli	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD2_k127_8311720_0	1536770.R50345_04965	9.19e-230	718.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4HCGH@91061|Bacilli,26WDN@186822|Paenibacillaceae	91061|Bacilli	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
HKD2_k127_8311720_5	985665.HPL003_21835	5.332e-05	45.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,271Z5@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type III-like domain	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD2_k127_8314119_3	796606.BMMGA3_02470	3.147e-36	139.0	28H8D@1|root,2Z7KA@2|Bacteria,1UB21@1239|Firmicutes,4HA47@91061|Bacilli,1ZB3G@1386|Bacillus	91061|Bacilli	-	-	ykoS	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8314119_0	545693.BMQ_1671	5.016e-166	530.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HBCD@91061|Bacilli,1ZQUR@1386|Bacillus	91061|Bacilli	M	Monogalactosyldiacylglycerol (MGDG) synthase	ugtP5	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD2_k127_8314119_1	1236976.JCM16418_2609	1.395e-132	440.0	COG2199@1|root,COG2199@2|Bacteria,1TR65@1239|Firmicutes,4HBA6@91061|Bacilli,26RG7@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
HKD2_k127_8314119_2	1403313.AXBR01000002_gene4165	3.35e-50	180.0	COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,4HATV@91061|Bacilli,1ZC2P@1386|Bacillus	91061|Bacilli	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
HKD2_k127_8337087_1	1307436.PBF_04653	1.115e-87	299.0	COG0840@1|root,COG0840@2|Bacteria,1V8HF@1239|Firmicutes,4HJW4@91061|Bacilli,1ZE90@1386|Bacillus	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
HKD2_k127_8337087_0	315730.BcerKBAB4_3279	2.777e-124	404.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,1ZCRG@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD2_k127_8337087_2	1120971.AUCA01000001_gene1725	1.516e-25	108.0	COG1277@1|root,COG1277@2|Bacteria,1V2P1@1239|Firmicutes,4HG7C@91061|Bacilli	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD2_k127_8343308_3	1169144.KB910980_gene1537	2.838e-96	318.0	COG0463@1|root,COG0463@2|Bacteria,1V8T1@1239|Firmicutes,4HKMR@91061|Bacilli,1ZD6C@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD2_k127_8343308_2	218284.CCDN010000009_gene4286	3.52e-147	475.0	2DJW7@1|root,307JY@2|Bacteria,1V5TV@1239|Firmicutes,4IRV9@91061|Bacilli,1ZRYE@1386|Bacillus	91061|Bacilli	S	EpsG family	-	-	-	ko:K19419	-	-	-	-	ko00000,ko02000	9.B.183.1.9	-	-	EpsG
HKD2_k127_8343308_1	1117379.BABA_10091	5.828e-156	502.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli,1ZEMI@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	epsF	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD2_k127_8343308_0	1196031.ALEG01000067_gene4782	5.351e-186	588.0	COG0438@1|root,COG0438@2|Bacteria,1V09V@1239|Firmicutes,4HM8X@91061|Bacilli,1ZAUY@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD2_k127_8385803_17	1340434.AXVA01000010_gene5484	1.196e-05	50.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8385803_12	1243664.CAVL020000008_gene4164	1.135e-32	128.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,4IS2P@91061|Bacilli,1ZS0T@1386|Bacillus	91061|Bacilli	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
HKD2_k127_8385803_11	866895.HBHAL_4944	5.672e-47	173.0	COG3439@1|root,COG3439@2|Bacteria,1VA5R@1239|Firmicutes,4HITT@91061|Bacilli,3NF65@45667|Halobacillus	91061|Bacilli	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
HKD2_k127_8385803_7	1403313.AXBR01000024_gene4831	3.121e-121	396.0	COG1388@1|root,COG1388@2|Bacteria,1V5FY@1239|Firmicutes,4HFU9@91061|Bacilli,1ZDDF@1386|Bacillus	91061|Bacilli	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8385803_1	1042163.BRLA_c023320	3.614e-283	878.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,26TPV@186822|Paenibacillaceae	91061|Bacilli	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD2_k127_8385803_6	574376.BAMA_20490	5.586e-124	404.0	29RA0@1|root,30CBJ@2|Bacteria,1U9JK@1239|Firmicutes,4IJQU@91061|Bacilli,1ZDR9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8385803_15	1174504.AJTN02000047_gene3865	4.342e-26	115.0	COG4903@1|root,COG4903@2|Bacteria,1TUGI@1239|Firmicutes,4HM0Y@91061|Bacilli,1ZJGM@1386|Bacillus	91061|Bacilli	K	ComK protein	-	-	-	-	-	-	-	-	-	-	-	-	ComK
HKD2_k127_8385803_5	1196031.ALEG01000029_gene3698	7.281e-135	432.0	COG0726@1|root,COG0726@2|Bacteria,1VD20@1239|Firmicutes,4HN1H@91061|Bacilli,1ZC2M@1386|Bacillus	91061|Bacilli	G	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD2_k127_8385803_8	1033734.CAET01000026_gene972	4.778e-106	347.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1ZCQB@1386|Bacillus	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
HKD2_k127_8385803_14	935836.JAEL01000142_gene4185	2.258e-26	110.0	2C58K@1|root,32Y9K@2|Bacteria,1VESG@1239|Firmicutes,4HQS0@91061|Bacilli,1ZIZ4@1386|Bacillus	91061|Bacilli	S	Sigma-G-dependent sporulation-specific SASP protein	csgA	-	-	-	-	-	-	-	-	-	-	-	CsgA
HKD2_k127_8385803_13	981383.AEWH01000050_gene19	4.642e-29	119.0	2DRQR@1|root,33CNQ@2|Bacteria,1VGGC@1239|Firmicutes,4HR2A@91061|Bacilli	91061|Bacilli	S	Small, acid-soluble spore protein, gamma-type	sspE	-	-	ko:K06422	-	-	-	-	ko00000	-	-	-	SASP_gamma
HKD2_k127_8385803_2	666686.B1NLA3E_07785	9.885e-158	503.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus	91061|Bacilli	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
HKD2_k127_8385803_4	1408303.JNJJ01000082_gene2005	3.005e-142	454.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,4HBSI@91061|Bacilli,1ZB9S@1386|Bacillus	91061|Bacilli	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
HKD2_k127_8385803_16	666686.B1NLA3E_07775	1.474e-23	100.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,4HR3T@91061|Bacilli,1ZJY0@1386|Bacillus	91061|Bacilli	H	Thiamine biosynthesis	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD2_k127_8385803_3	1117379.BABA_01460	2.961e-152	489.0	COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,1ZCZM@1386|Bacillus	91061|Bacilli	E	Glycine oxidase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
HKD2_k127_8385803_10	1243664.CAVL020000036_gene2725	1.812e-75	258.0	COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,1ZH29@1386|Bacillus	91061|Bacilli	H	Transcriptional regulator TenI	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.3.99.10	ko:K10810	ko00730,ko01100,map00730,map01100	-	R09977	RC02766	ko00000,ko00001,ko01000,ko03000	-	-	-	TMP-TENI
HKD2_k127_8385803_9	1169144.KB910935_gene2035	1.09e-87	294.0	COG1388@1|root,COG1388@2|Bacteria,1V4GT@1239|Firmicutes,4IPSP@91061|Bacilli	91061|Bacilli	M	LysM domain	M1-670	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8385803_0	1403313.AXBR01000010_gene1073	0.0	1595.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus	91061|Bacilli	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	snf	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HKD2_k127_844171_2	1536774.H70357_26050	0.0002003	45.0	COG0789@1|root,COG0789@2|Bacteria,1VB69@1239|Firmicutes,4HTK2@91061|Bacilli,26Z8Z@186822|Paenibacillaceae	91061|Bacilli	K	MerR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD2_k127_844171_1	1395513.P343_00515	7.096e-98	324.0	COG1647@1|root,COG1647@2|Bacteria,1TVX4@1239|Firmicutes,4HFF2@91061|Bacilli,26PSA@186821|Sporolactobacillaceae	91061|Bacilli	S	Serine hydrolase (FSH1)	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
HKD2_k127_844171_0	1123284.KB899052_gene1931	1.134e-106	350.0	COG2267@1|root,COG2267@2|Bacteria,1UHU6@1239|Firmicutes,4ISA0@91061|Bacilli	91061|Bacilli	I	Alpha beta hydrolase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD2_k127_8479862_8	1211814.CAPG01000098_gene4387	2.328e-19	87.0	2DR8Z@1|root,33AQV@2|Bacteria,1VK7N@1239|Firmicutes,4HRWZ@91061|Bacilli,1ZISI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8479862_9	1174504.AJTN02000265_gene275	3.986e-13	68.0	29S78@1|root,30DBR@2|Bacteria,1UB46@1239|Firmicutes,4IMGS@91061|Bacilli,1ZK4I@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8479862_12	1051501.AYTL01000014_gene1339	0.0002999	44.0	2DIA4@1|root,302HW@2|Bacteria,1U5Y3@1239|Firmicutes,4IM9X@91061|Bacilli,1ZJJZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8479862_6	861530.ALOZ01000027_gene420	1.108e-24	104.0	2EIAV@1|root,33C29@2|Bacteria,1VMAE@1239|Firmicutes,4HRG9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8479862_7	1123239.KB898630_gene2582	2.298e-19	88.0	2ED1A@1|root,336Y8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8479862_10	698769.JFBD01000042_gene814	4.212e-13	68.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8479862_0	1403313.AXBR01000025_gene4933	9.096e-154	489.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,1ZCJY@1386|Bacillus	91061|Bacilli	E	Belongs to the arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD2_k127_8479862_5	1034347.CAHJ01000039_gene4738	5.71e-44	170.0	2CHZZ@1|root,32S6Y@2|Bacteria,1VA01@1239|Firmicutes,4IJSI@91061|Bacilli,1ZJVW@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8479862_4	1034347.CAHJ01000039_gene4737	1.825e-44	164.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,1ZHSQ@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yhcF	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HKD2_k127_8479862_3	1034347.CAHJ01000039_gene4736	1.105e-96	321.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HC2V@91061|Bacilli,1ZCBF@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	yhcG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_8479862_1	1403313.AXBR01000025_gene4931	1.249e-99	327.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD2_k127_8479862_2	1403313.AXBR01000025_gene4930	2.616e-97	323.0	COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli,1ZE1K@1386|Bacillus	91061|Bacilli	K	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation	rsiW	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
HKD2_k127_8487670_1	1403313.AXBR01000021_gene3245	1.674e-66	227.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,1ZAQR@1386|Bacillus	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_8487670_0	1403313.AXBR01000021_gene3244	8.701e-253	784.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	pdhD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD2_k127_8543303_3	796606.BMMGA3_10905	3.685e-55	196.0	COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus	91061|Bacilli	S	Calcineurin-like phosphoesterase superfamily domain	ypbG	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
HKD2_k127_8543303_1	1307436.PBF_12552	2.259e-118	387.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1TQXC@1239|Firmicutes,4HCSG@91061|Bacilli,1ZD8Q@1386|Bacillus	91061|Bacilli	K	MerR family transcriptional regulator	ycgE	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
HKD2_k127_8543303_2	1340434.AXVA01000013_gene373	1.793e-80	272.0	COG4862@1|root,COG4862@2|Bacteria,1V1B7@1239|Firmicutes,4HBM5@91061|Bacilli,1ZF7G@1386|Bacillus	91061|Bacilli	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC	mecB	GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
HKD2_k127_8543303_0	1294265.JCM21738_84	7.544e-149	472.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gudB	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.2	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD2_k127_8549559_1	1027292.HMPREF9372_2780	1.701e-29	117.0	COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,26EH1@186818|Planococcaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	mhqA	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD2_k127_8549559_0	1121090.KB894685_gene3909	2.519e-106	360.0	COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,1ZBCT@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K06595	-	-	-	-	ko00000,ko02035	-	-	-	MCPsignal,Protoglobin
HKD2_k127_8549559_2	1033734.CAET01000025_gene1062	4.959e-09	64.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HAAU@91061|Bacilli,1ZSDH@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA
HKD2_k127_8565828_13	1034347.CAHJ01000065_gene3007	4.351e-55	195.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	iYO844.BSU32750	ABC_tran,NIL
HKD2_k127_8565828_9	1403313.AXBR01000013_gene1417	9.019e-108	352.0	COG2011@1|root,COG2011@2|Bacteria,1TR59@1239|Firmicutes,4H9NA@91061|Bacilli,1ZCW0@1386|Bacillus	91061|Bacilli	P	COG2011 ABC-type metal ion transport system, permease component	metI	GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348	-	ko:K02069,ko:K02072	ko02010,map02010	M00211,M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24,9.B.25.1	-	-	BPD_transp_1
HKD2_k127_8565828_7	1403313.AXBR01000013_gene1418	6.248e-135	434.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,1ZATZ@1386|Bacillus	91061|Bacilli	P	Belongs to the NlpA lipoprotein family	metQ	-	-	ko:K02072,ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD2_k127_8565828_5	1403313.AXBR01000013_gene1421	1.534e-156	495.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,1ZAW4@1386|Bacillus	91061|Bacilli	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HKD2_k127_8565828_3	1174504.AJTN02000230_gene1331	2.137e-218	683.0	COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,1ZATY@1386|Bacillus	91061|Bacilli	O	assembly protein SufD	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HKD2_k127_8565828_1	1403313.AXBR01000013_gene1423	1.527e-244	757.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,1ZB79@1386|Bacillus	91061|Bacilli	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
HKD2_k127_8565828_10	1034347.CAHJ01000065_gene3000	3.541e-67	231.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,1ZFQ8@1386|Bacillus	91061|Bacilli	C	COG0822 NifU homolog involved in Fe-S cluster formation	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HKD2_k127_8565828_0	1403313.AXBR01000013_gene1425	9.927e-296	908.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,1ZCDS@1386|Bacillus	91061|Bacilli	O	FeS cluster assembly	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
HKD2_k127_8565828_8	1403313.AXBR01000013_gene1427	5.208e-129	417.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,1ZAPI@1386|Bacillus	91061|Bacilli	S	membrane transporter protein	yunE	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD2_k127_8565828_2	1403313.AXBR01000013_gene1428	9.981e-234	730.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1ZCJ8@1386|Bacillus	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yunD	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HKD2_k127_8565828_15	1034347.CAHJ01000065_gene2996	8.2e-42	155.0	COG3377@1|root,COG3377@2|Bacteria,1VAP7@1239|Firmicutes,4HKBM@91061|Bacilli,1ZHYB@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1805)	yunC	-	-	-	-	-	-	-	-	-	-	-	DUF1805
HKD2_k127_8565828_6	796606.BMMGA3_14315	1.131e-137	446.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,1ZCMY@1386|Bacillus	91061|Bacilli	T	HD domain	cnpD3	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
HKD2_k127_8565828_11	1403313.AXBR01000013_gene1431	1.675e-64	229.0	2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,4HKBP@91061|Bacilli,1ZFY9@1386|Bacillus	91061|Bacilli	S	Sporulation protein YunB (Spo_YunB)	yunB	-	-	-	-	-	-	-	-	-	-	-	Spore_YunB
HKD2_k127_8565828_4	1403313.AXBR01000013_gene1432	2.473e-159	508.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli,1ZAQT@1386|Bacillus	91061|Bacilli	M	Peptidase, M23	lytH	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD2_k127_8565828_12	1403313.AXBR01000013_gene1434	1.649e-59	211.0	2DBQ9@1|root,2ZACY@2|Bacteria,1V0WH@1239|Firmicutes,4HEH4@91061|Bacilli,1ZR7V@1386|Bacillus	91061|Bacilli	S	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)	yutC	-	-	-	-	-	-	-	-	-	-	-	Spore_YhcN_YlaJ
HKD2_k127_8565828_14	1403313.AXBR01000013_gene1435	1.501e-51	183.0	COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,1ZHY5@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yutD	-	-	-	-	-	-	-	-	-	-	-	DUF1027
HKD2_k127_8565828_18	1340434.AXVA01000016_gene701	1.008e-14	75.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8565828_20	1385514.N782_03495	1.265e-08	57.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8565828_17	406124.ACPC01000020_gene3719	1.47e-32	128.0	2DZWK@1|root,32VKV@2|Bacteria,1VGZB@1239|Firmicutes,4HKJ4@91061|Bacilli,1ZHSM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8565828_16	1403313.AXBR01000013_gene1437	9.924e-41	151.0	2CGTU@1|root,32Z9H@2|Bacteria,1VG36@1239|Firmicutes,4HNI4@91061|Bacilli,1ZI34@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3055)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3055
HKD2_k127_8590722_2	1340434.AXVA01000003_gene2195	4.422e-39	147.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus	91061|Bacilli	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	dltA	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_8590722_0	1340434.AXVA01000004_gene2688	8.733e-195	612.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,1ZCX1@1386|Bacillus	91061|Bacilli	M	membrane protein involved in D-alanine export	dltB	-	-	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
HKD2_k127_8590722_3	1340434.AXVA01000004_gene2687	1.467e-33	130.0	COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,1ZJEB@1386|Bacillus	91061|Bacilli	IQ	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	PP-binding
HKD2_k127_8590722_1	1340434.AXVA01000004_gene2686	5.18e-192	605.0	COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,1ZD6Q@1386|Bacillus	91061|Bacilli	M	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)	dltD	-	-	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	DltD
HKD2_k127_8592748_3	1121091.AUMP01000002_gene2226	8.594e-19	88.0	COG1226@1|root,COG1226@2|Bacteria,1TS7X@1239|Firmicutes,4HCIB@91061|Bacilli	91061|Bacilli	P	potassium channel protein	yugO	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
HKD2_k127_8592748_0	1403313.AXBR01000013_gene1506	5.08e-240	745.0	COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus	91061|Bacilli	M	Glycoside Hydrolase Family	yaaH	-	-	ko:K06306	-	-	-	-	ko00000	-	-	-	Glyco_hydro_18,LysM
HKD2_k127_8592748_2	345219.Bcoa_0435	4.575e-31	122.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus	91061|Bacilli	S	spore protein	B4168_3115	-	-	ko:K06419	-	-	-	-	ko00000	-	-	-	SASP
HKD2_k127_8592748_1	1403313.AXBR01000013_gene1508	3.468e-94	314.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,1ZAVP@1386|Bacillus	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
HKD2_k127_8592756_0	1340434.AXVA01000033_gene33	1.71e-113	370.0	COG0841@1|root,COG0841@2|Bacteria,1VSZS@1239|Firmicutes,4HTM3@91061|Bacilli,1ZEW5@1386|Bacillus	91061|Bacilli	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD2_k127_8592756_1	1461580.CCAS010000048_gene3524	5.037e-58	203.0	COG0640@1|root,COG0640@2|Bacteria,1V9XT@1239|Firmicutes,4HKP8@91061|Bacilli,1ZI0T@1386|Bacillus	91061|Bacilli	K	ArsR family transcriptional regulator	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
HKD2_k127_8621117_4	1169144.KB910942_gene2597	2.015e-21	96.0	2EH2H@1|root,33AUF@2|Bacteria,1VKXK@1239|Firmicutes,4HRIP@91061|Bacilli,1ZIU3@1386|Bacillus	91061|Bacilli	S	asexual reproduction	sspH	-	-	ko:K06425	-	-	-	-	ko00000	-	-	-	SspH
HKD2_k127_8621117_3	1340434.AXVA01000022_gene3935	7.707e-57	202.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1
HKD2_k127_8621117_1	1385514.N782_10220	2.461e-98	329.0	COG0702@1|root,COG0702@2|Bacteria,1UY7W@1239|Firmicutes	1239|Firmicutes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
HKD2_k127_8621117_0	1461580.CCAS010000047_gene3497	8.057e-188	598.0	COG3071@1|root,COG3071@2|Bacteria,1UZ54@1239|Firmicutes,4HDMF@91061|Bacilli,1ZFGG@1386|Bacillus	91061|Bacilli	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8621117_2	1444306.JFZC01000069_gene1755	1.434e-85	300.0	2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,4HC1J@91061|Bacilli,26PDC@186821|Sporolactobacillaceae	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	XK27_11280	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8645336_4	1117379.BABA_14527	1.875e-28	118.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,4HAXZ@91061|Bacilli,1ZARP@1386|Bacillus	91061|Bacilli	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	dmpG	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
HKD2_k127_8645336_7	1294265.JCM21738_1838	9.787e-05	45.0	COG4768@1|root,COG4768@2|Bacteria,1UBBB@1239|Firmicutes,4IMQ8@91061|Bacilli,1ZKKT@1386|Bacillus	91061|Bacilli	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
HKD2_k127_8645336_1	1134413.ANNK01000087_gene273	1.916e-139	448.0	COG4569@1|root,COG4569@2|Bacteria,1TQJS@1239|Firmicutes,4HCRZ@91061|Bacilli,1ZEE6@1386|Bacillus	91061|Bacilli	Q	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds	mhpF	-	1.2.1.10	ko:K04073	ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00545,M00569	R00228,R01172	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
HKD2_k127_8645336_2	666686.B1NLA3E_09295	6.225e-112	367.0	COG3971@1|root,COG3971@2|Bacteria,1TQVG@1239|Firmicutes,4HBMC@91061|Bacilli,1ZC05@1386|Bacillus	91061|Bacilli	Q	2-keto-4-pentenoate hydratase	-	-	4.2.1.80	ko:K02554	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04781	RC00750,RC01213	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
HKD2_k127_8645336_0	1234664.AMRO01000077_gene3350	5.651e-264	820.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1WF7U@129337|Geobacillus	91061|Bacilli	C	Aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_8645336_3	634956.Geoth_1638	1.949e-103	342.0	COG1414@1|root,COG1414@2|Bacteria,1W784@1239|Firmicutes,4ICFU@91061|Bacilli,1WE99@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD2_k127_8645336_5	1403313.AXBR01000014_gene2247	1.981e-23	104.0	29JW2@1|root,306TD@2|Bacteria,1U0BH@1239|Firmicutes,4I9NA@91061|Bacilli,1ZISQ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2524)	ytzC	-	-	-	-	-	-	-	-	-	-	-	DUF2524
HKD2_k127_8645336_6	1033734.CAET01000065_gene2218	2.829e-22	97.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,1ZDAX@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	ybhF_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_8662465_0	1174504.AJTN02000249_gene779	0.0	1137.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus	91061|Bacilli	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
HKD2_k127_8662465_1	1403313.AXBR01000007_gene296	3.521e-169	540.0	COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,1ZAZQ@1386|Bacillus	91061|Bacilli	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
HKD2_k127_8662465_4	1211814.CAPG01000034_gene1758	7.393e-29	121.0	2DPQ6@1|root,332Y4@2|Bacteria,1VJD6@1239|Firmicutes,4HQPY@91061|Bacilli,1ZJDN@1386|Bacillus	91061|Bacilli	S	Inner spore coat protein D	-	-	-	ko:K06327	-	-	-	-	ko00000	-	-	-	Spore-coat_CotD
HKD2_k127_8662465_2	1403313.AXBR01000007_gene294	8.068e-83	279.0	COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,1ZFYS@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0398 family	ypsA	-	-	-	-	-	-	-	-	-	-	-	DUF1273
HKD2_k127_8662465_3	1403313.AXBR01000007_gene293	2.481e-52	185.0	COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,1ZQAY@1386|Bacillus	91061|Bacilli	D	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation	gpsB	-	-	-	-	-	-	-	-	-	-	-	DivIVA
HKD2_k127_8664353_2	1403313.AXBR01000021_gene3253	3.655e-86	285.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZBCD@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD2_k127_8664353_4	1403313.AXBR01000021_gene3252	5.135e-23	99.0	COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,1ZIUI@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0356 family	ykzG	-	-	-	-	-	-	-	-	-	-	-	DUF1447
HKD2_k127_8664353_1	1403313.AXBR01000021_gene3251	8.397e-121	392.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1ZBY4@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	ykrA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
HKD2_k127_8664353_0	1121091.AUMP01000044_gene3899	6.715e-134	433.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli	91061|Bacilli	L	Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
HKD2_k127_8664353_3	981383.AEWH01000050_gene148	9.327e-47	172.0	COG2963@1|root,COG2963@2|Bacteria,1V771@1239|Firmicutes,4HJ16@91061|Bacilli	91061|Bacilli	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8686912_0	1295642.H839_08953	1.136e-149	481.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,4HAU0@91061|Bacilli	91061|Bacilli	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
HKD2_k127_8686912_1	1295642.H839_08958	2.038e-83	290.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1WG5M@129337|Geobacillus	91061|Bacilli	NT	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
HKD2_k127_8700386_0	1403313.AXBR01000007_gene265	5.483e-208	652.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,1ZC00@1386|Bacillus	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU13130	Aldedh
HKD2_k127_8700386_1	1403313.AXBR01000007_gene266	2.111e-182	576.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,1ZAPU@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
HKD2_k127_8700386_2	1403313.AXBR01000007_gene268	3.243e-149	478.0	COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus	91061|Bacilli	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	hmp	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057	1.14.12.17,1.18.1.3	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Globin,NAD_binding_1
HKD2_k127_8747985_4	1499680.CCFE01000021_gene2337	1.558e-155	498.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4HC54@91061|Bacilli,1ZEXE@1386|Bacillus	91061|Bacilli	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD2_k127_8747985_2	1307436.PBF_17959	2.929e-161	517.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4HD4Q@91061|Bacilli,1ZDNG@1386|Bacillus	91061|Bacilli	T	signal transduction protein containing EAL and modified HD-GYP domains	yuxH	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
HKD2_k127_8747985_12	1160707.AJIK01000002_gene580	4.549e-85	286.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HDFU@91061|Bacilli,26EX2@186818|Planococcaceae	91061|Bacilli	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
HKD2_k127_8747985_11	420246.GTNG_0153	4.942e-87	288.0	COG1853@1|root,COG1853@2|Bacteria,1V1X6@1239|Firmicutes,4HGJ2@91061|Bacilli,1WFHC@129337|Geobacillus	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD2_k127_8747985_19	1211035.CD30_00145	1.901e-13	72.0	29TMW@1|root,30EVH@2|Bacteria,1UD0G@1239|Firmicutes,4IPGJ@91061|Bacilli,3IYX1@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8747985_10	1174504.AJTN02000209_gene3295	1.246e-88	297.0	2BH01@1|root,32B05@2|Bacteria,1V7CB@1239|Firmicutes,4HJUQ@91061|Bacilli,1ZEG0@1386|Bacillus	91061|Bacilli	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
HKD2_k127_8747985_3	1117379.BABA_08406	3.058e-157	509.0	COG3071@1|root,COG3071@2|Bacteria,1UZ54@1239|Firmicutes,4HDMF@91061|Bacilli,1ZFGG@1386|Bacillus	91061|Bacilli	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8747985_18	1403313.AXBR01000002_gene4442	3.906e-39	147.0	2E59K@1|root,3301W@2|Bacteria,1VF4H@1239|Firmicutes,4HPY9@91061|Bacilli,1ZQTK@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3892)	ywsA	-	-	-	-	-	-	-	-	-	-	-	DUF3892
HKD2_k127_8747985_15	1347369.CCAD010000083_gene2791	3.023e-63	219.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HIEM@91061|Bacilli,1ZQR8@1386|Bacillus	91061|Bacilli	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
HKD2_k127_8747985_13	333138.LQ50_03810	4.48e-76	258.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HH2P@91061|Bacilli,1ZFWF@1386|Bacillus	91061|Bacilli	P	COG2059 Chromate transport protein ChrA	srpC_2	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD2_k127_8747985_14	1033734.CAET01000045_gene593	1.798e-73	252.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4HFWH@91061|Bacilli,1ZFJR@1386|Bacillus	91061|Bacilli	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD2_k127_8747985_20	1034347.CAHJ01000045_gene534	2.535e-08	55.0	COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4HB23@91061|Bacilli,1ZCVJ@1386|Bacillus	91061|Bacilli	E	gamma-glutamyltransferase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD2_k127_8747985_0	1132442.KB889752_gene1238	2.57e-233	727.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	yxeK	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_8747985_21	1340434.AXVA01000010_gene5484	1.005e-05	49.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8747985_5	1132442.KB889752_gene1239	7.227e-149	478.0	COG0715@1|root,COG0715@2|Bacteria,1V9ZY@1239|Firmicutes,4HTB1@91061|Bacilli,1ZDC2@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
HKD2_k127_8747985_8	1536775.H70737_03665	1.694e-135	436.0	COG0600@1|root,COG0600@2|Bacteria,1U8Z7@1239|Firmicutes,4HAZY@91061|Bacilli,276HE@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD2_k127_8747985_6	621372.ACIH01000002_gene420	1.406e-141	452.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,26RHF@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD2_k127_8747985_1	1132442.KB889752_gene1238	4.422e-180	573.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	yxeK	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_8747985_16	1132442.KB889752_gene1481	6.747e-57	204.0	COG1846@1|root,COG1846@2|Bacteria,1VWCI@1239|Firmicutes,4I356@91061|Bacilli,1ZKVT@1386|Bacillus	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD2_k127_8747985_7	1145276.T479_13795	2.369e-141	456.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4H9YM@91061|Bacilli,3IVNF@400634|Lysinibacillus	91061|Bacilli	C	Catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones	namA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN
HKD2_k127_8747985_9	1121422.AUMW01000006_gene683	1.972e-123	411.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_8747985_17	1121422.AUMW01000006_gene684	2.11e-39	148.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,261P1@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_8750314_8	1403313.AXBR01000023_gene2347	7.818e-51	181.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,1ZH2A@1386|Bacillus	91061|Bacilli	S	metal-sulfur cluster biosynthetic enzyme	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
HKD2_k127_8750314_6	1403313.AXBR01000023_gene2348	5.983e-100	333.0	COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,1ZBIJ@1386|Bacillus	91061|Bacilli	S	COG1073 Hydrolases of the alpha beta superfamily	yitV	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
HKD2_k127_8750314_1	1403313.AXBR01000023_gene2349	2.852e-133	428.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,1ZC4W@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	yitU	-	3.1.3.104	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3
HKD2_k127_8750314_10	1174504.AJTN02000235_gene3739	5.222e-13	69.0	2EESV@1|root,338KD@2|Bacteria,1VFET@1239|Firmicutes,4HP8V@91061|Bacilli,1ZIWM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8750314_9	1403313.AXBR01000023_gene2351	1.015e-15	78.0	2A0JV@1|root,30NQ2@2|Bacteria,1TWUS@1239|Firmicutes,4HS9X@91061|Bacilli,1ZJXW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3813)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3813
HKD2_k127_8750314_3	1403313.AXBR01000023_gene2353	2.245e-125	406.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZDFA@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yitT	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD2_k127_8750314_0	1403313.AXBR01000023_gene2354	3.485e-141	452.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yitS	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD2_k127_8750314_7	1403313.AXBR01000023_gene2356	9.322e-84	279.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,1ZFPU@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
HKD2_k127_8750314_5	1131730.BAVI_03649	1.715e-104	346.0	COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,4HGVU@91061|Bacilli,1ZQYT@1386|Bacillus	91061|Bacilli	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD2_k127_8750314_4	871968.DESME_08415	1.305e-121	404.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,26006@186807|Peptococcaceae	186801|Clostridia	S	PFAM RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
HKD2_k127_8750314_2	1347086.CCBA010000010_gene1735	4.125e-133	433.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4HBP3@91061|Bacilli,1ZFXU@1386|Bacillus	91061|Bacilli	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD2_k127_8757664_2	1499968.TCA2_5981	2.917e-56	204.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	Cu_amine_oxidN1,SH3_3
HKD2_k127_8757664_3	1307436.PBF_15229	1.289e-45	166.0	2CI5E@1|root,32S7D@2|Bacteria,1VA1W@1239|Firmicutes,4HKCJ@91061|Bacilli,1ZHWY@1386|Bacillus	91061|Bacilli	-	-	yxiS	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8757664_4	398511.BpOF4_20134	1.035e-29	118.0	2EQ6D@1|root,33HSQ@2|Bacteria,1VMIA@1239|Firmicutes,4HR4U@91061|Bacilli,1ZGPH@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8757664_1	1132442.KB889752_gene438	1.534e-76	274.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA
HKD2_k127_8757664_6	1294265.JCM21738_5005	3.569e-05	48.0	COG1700@1|root,COG1700@2|Bacteria,1TT3T@1239|Firmicutes,4HCS2@91061|Bacilli,1ZAY5@1386|Bacillus	91061|Bacilli	S	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K09124	-	-	-	-	ko00000	-	-	-	DUF2357,PDDEXK_7
HKD2_k127_8757664_5	1227360.C176_14112	3.042e-10	64.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26GM0@186818|Planococcaceae	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	tlpA3	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
HKD2_k127_8757664_0	1347086.CCBA010000006_gene4686	3.169e-96	317.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZB5H@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	XK27_00915	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD2_k127_8805912_1	109871.XP_006683435.1	4.608e-161	515.0	COG0841@1|root,2RHH3@2759|Eukaryota,39SPV@33154|Opisthokonta,3PB7Q@4751|Fungi	4751|Fungi	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD2_k127_8805912_3	1174504.AJTN02000099_gene2596	4.644e-85	287.0	COG2755@1|root,COG2755@2|Bacteria,1UH1X@1239|Firmicutes,4HE8E@91061|Bacilli,1ZG9K@1386|Bacillus	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,SLH,fn3
HKD2_k127_8805912_2	666686.B1NLA3E_02600	1.264e-97	322.0	COG2230@1|root,COG2230@2|Bacteria,1V4JG@1239|Firmicutes,4HH18@91061|Bacilli,1ZE3E@1386|Bacillus	91061|Bacilli	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,DOT1,Methyltransf_32
HKD2_k127_8805912_0	796606.BMMGA3_04150	3.309e-228	715.0	COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus	91061|Bacilli	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
HKD2_k127_8805912_10	1340434.AXVA01000010_gene5484	3.934e-05	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8805912_8	935837.JAEK01000088_gene447	3.564e-21	94.0	2BQKA@1|root,32JGC@2|Bacteria,1UAXE@1239|Firmicutes,4IMA8@91061|Bacilli,1ZJMF@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8805912_7	634956.Geoth_0213	4.189e-62	217.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli,1WG9I@129337|Geobacillus	91061|Bacilli	K	TipAS antibiotic-recognition domain	mta	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
HKD2_k127_8805912_6	1121085.AUCI01000005_gene915	9.177e-63	227.0	COG2002@1|root,COG5607@1|root,COG2002@2|Bacteria,COG5607@2|Bacteria,1VHQT@1239|Firmicutes,4HPEI@91061|Bacilli	91061|Bacilli	K	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
HKD2_k127_8805912_9	1121091.AUMP01000002_gene2062	3.599e-06	53.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	KfrA_N
HKD2_k127_8805912_4	1034347.CAHJ01000073_gene2826	7.524e-81	272.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,4HHG6@91061|Bacilli,1ZFS2@1386|Bacillus	91061|Bacilli	S	Thiamine-precursor transporter protein (ThiW)	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
HKD2_k127_8805912_5	1211814.CAPG01000020_gene737	2.544e-73	249.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,1ZCIY@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
HKD2_k127_8805946_1	1403313.AXBR01000015_gene2078	2.07e-55	198.0	COG0515@1|root,COG0515@2|Bacteria,1V7XF@1239|Firmicutes,4HIH6@91061|Bacilli,1ZS5Q@1386|Bacillus	91061|Bacilli	KLT	serine threonine protein kinase	yrzF	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RIO1,WaaY
HKD2_k127_8805946_0	109871.XP_006683435.1	0.0	1073.0	COG0841@1|root,2RHH3@2759|Eukaryota,39SPV@33154|Opisthokonta,3PB7Q@4751|Fungi	4751|Fungi	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD2_k127_8825_2	666686.B1NLA3E_09655	6.955e-64	219.0	COG2141@1|root,COG2141@2|Bacteria,1TW8W@1239|Firmicutes,4HBIF@91061|Bacilli,1ZR3K@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	msuD	-	1.14.14.35	ko:K17228	ko00920,map00920	-	R10203	RC02556,RC03080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HKD2_k127_8825_0	666686.B1NLA3E_09660	2.896e-184	579.0	COG0189@1|root,COG0189@2|Bacteria,1TSHN@1239|Firmicutes,4HBFG@91061|Bacilli,1ZDEU@1386|Bacillus	91061|Bacilli	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
HKD2_k127_8825_1	1403313.AXBR01000008_gene640	6.949e-77	263.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	mccB	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27250	Cys_Met_Meta_PP
HKD2_k127_8831182_0	1196031.ALEG01000067_gene4795	3.814e-273	854.0	COG5434@1|root,COG5434@2|Bacteria,1V10E@1239|Firmicutes,4HFE0@91061|Bacilli,1ZPVM@1386|Bacillus	91061|Bacilli	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,SLH,fn3
HKD2_k127_8881232_3	1132442.KB889752_gene3696	3.407e-36	138.0	COG2318@1|root,COG2318@2|Bacteria,1VG45@1239|Firmicutes,4HPNV@91061|Bacilli,1ZH17@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD2_k127_8881232_0	1132442.KB889752_gene3697	4.723e-226	702.0	COG3435@1|root,COG3435@2|Bacteria,1UYG0@1239|Firmicutes,4HCWV@91061|Bacilli,1ZBMC@1386|Bacillus	91061|Bacilli	Q	Cupin domain	-	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
HKD2_k127_8881232_2	1347086.CCBA010000003_gene3840	2.534e-166	533.0	COG0654@1|root,COG0654@2|Bacteria,1U29G@1239|Firmicutes,4HF0P@91061|Bacilli,1ZE9I@1386|Bacillus	91061|Bacilli	CH	FAD binding domain	-	-	1.14.13.24	ko:K22270	ko00362,ko01120,map00362,map01120	-	R02589	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
HKD2_k127_8881232_1	1211814.CAPG01000027_gene1048	1.197e-208	658.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,1ZAP7@1386|Bacillus	91061|Bacilli	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HKD2_k127_8915394_12	1403313.AXBR01000007_gene488	6.365e-147	467.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,4HA1M@91061|Bacilli,1ZBNB@1386|Bacillus	91061|Bacilli	KT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	GO:0000003,GO:0000156,GO:0000160,GO:0000910,GO:0003674,GO:0006355,GO:0007049,GO:0007154,GO:0007165,GO:0008150,GO:0008356,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019954,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032506,GO:0035556,GO:0042173,GO:0042710,GO:0043934,GO:0043937,GO:0043938,GO:0044010,GO:0044085,GO:0044764,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051252,GO:0051301,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090529,GO:0090604,GO:0090606,GO:1903506,GO:2000112,GO:2001141	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
HKD2_k127_8915394_11	1174504.AJTN02000204_gene2740	9.455e-153	499.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,4H9TJ@91061|Bacilli,1ZC1A@1386|Bacillus	91061|Bacilli	L	Flagellar Assembly Protein A	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
HKD2_k127_8915394_17	935837.JAEK01000001_gene2366	3.151e-28	115.0	2E54T@1|root,32ZXQ@2|Bacteria,1VFDB@1239|Firmicutes,4HNU1@91061|Bacilli,1ZIWH@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2627)	yqzF	-	-	-	-	-	-	-	-	-	-	-	DUF2627
HKD2_k127_8915394_4	1403313.AXBR01000007_gene484	5.249e-233	728.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZBCS@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	bfmBC	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD2_k127_8915394_20	1385514.N782_03495	0.0001477	46.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8915394_9	1403313.AXBR01000007_gene483	1.124e-185	583.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,1ZCCJ@1386|Bacillus	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
HKD2_k127_8915394_7	1174504.AJTN02000204_gene2732	6.993e-196	612.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1ZC0X@1386|Bacillus	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bfmBAB	-	1.2.4.4	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU24040	Transket_pyr,Transketolase_C
HKD2_k127_8915394_10	1033734.CAET01000077_gene2935	6.449e-163	522.0	COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,1ZC6F@1386|Bacillus	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdB	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_8915394_2	1403313.AXBR01000007_gene480	6.585e-271	846.0	COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,1ZAVR@1386|Bacillus	91061|Bacilli	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HKD2_k127_8915394_0	1403313.AXBR01000007_gene479	0.0	1300.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,1ZCKD@1386|Bacillus	91061|Bacilli	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
HKD2_k127_8915394_8	1403313.AXBR01000007_gene478	8.276e-189	595.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H9ZJ@91061|Bacilli,1ZC78@1386|Bacillus	91061|Bacilli	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HKD2_k127_8915394_15	1274524.BSONL12_07317	9.663e-73	247.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZFKZ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HKD2_k127_8915394_13	1403313.AXBR01000007_gene472	1.361e-137	444.0	COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,1ZBBI@1386|Bacillus	91061|Bacilli	S	Putative aromatic acid exporter C-terminal domain	yqjA	-	-	-	-	-	-	-	-	-	-	-	ArAE_1,ArAE_1_C
HKD2_k127_8915394_14	1403313.AXBR01000007_gene471	2.072e-75	256.0	COG1376@1|root,COG1376@2|Bacteria,1V26F@1239|Firmicutes,4HG56@91061|Bacilli,1ZGC7@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yqjB	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD2_k127_8915394_16	1403313.AXBR01000007_gene470	3.201e-62	218.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4HCP5@91061|Bacilli,1ZHE7@1386|Bacillus	91061|Bacilli	E	COG0346 Lactoylglutathione lyase and related lyases	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HKD2_k127_8915394_1	935836.JAEL01000043_gene4310	2.995e-297	916.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus	91061|Bacilli	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	yqjD	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD2_k127_8915394_5	1403313.AXBR01000007_gene467	1.178e-203	638.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus	91061|Bacilli	E	COG2195 Di- and tripeptidases	yqjE	-	3.4.11.14,3.4.11.4	ko:K01258,ko:K01263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD2_k127_8915394_6	1403313.AXBR01000007_gene466	2.383e-201	634.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,1ZAZZ@1386|Bacillus	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD2_k127_8915394_3	1403313.AXBR01000007_gene465	3.025e-270	836.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus	91061|Bacilli	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
HKD2_k127_8918850_2	1385514.N782_03495	2.178e-06	49.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8918850_1	1403313.AXBR01000002_gene4243	4.538e-20	91.0	2CEJ8@1|root,33H3W@2|Bacteria,1VMMF@1239|Firmicutes,4HRK8@91061|Bacilli,1ZIWC@1386|Bacillus	91061|Bacilli	-	-	yfjT	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8918850_0	1174504.AJTN02000154_gene936	1.143e-300	926.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,1ZBHE@1386|Bacillus	91061|Bacilli	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
HKD2_k127_8922238_3	1243664.CAVL020000010_gene4540	1.703e-173	546.0	COG1960@1|root,COG1960@2|Bacteria,1VQUR@1239|Firmicutes,4HU1X@91061|Bacilli,1ZE36@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	ko:K04117	ko00362,ko01120,map00362,map01120	M00540	R05619	RC02035	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_8922238_7	1174504.AJTN02000209_gene3288	1.153e-40	154.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT,MaoC_dehydrat_N,MaoC_dehydratas
HKD2_k127_8922238_4	1174504.AJTN02000209_gene3289	1.016e-151	482.0	COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,1ZCX0@1386|Bacillus	91061|Bacilli	H	Enoyl-CoA hydratase/isomerase	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD2_k127_8922238_0	1174504.AJTN02000209_gene3290	1.463e-282	875.0	COG0318@1|root,COG0318@2|Bacteria,1UYF9@1239|Firmicutes,4IQIM@91061|Bacilli	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_8922238_6	1174504.AJTN02000209_gene3291	1.337e-123	399.0	COG1028@1|root,COG1028@2|Bacteria,1TR8Y@1239|Firmicutes,4HFAC@91061|Bacilli,1ZFFW@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.3.1.58	ko:K07535,ko:K10620	ko00362,ko00622,ko01120,ko01220,map00362,map00622,map01120,map01220	M00539,M00540	R05240,R05582	RC00057,RC00154	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD2_k127_8922238_2	1174504.AJTN02000035_gene3038	3.949e-183	580.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD2_k127_8922238_5	1243664.CAVL020000045_gene2124	2.168e-144	461.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZB8X@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD2_k127_8922238_1	1243664.CAVL020000045_gene2123	2.642e-197	620.0	COG1960@1|root,COG1960@2|Bacteria,1TR1Y@1239|Firmicutes,4HC1N@91061|Bacilli,1ZD47@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_8922238_8	767817.Desgi_1925	3.4e-17	82.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD2_k127_8968961_4	935836.JAEL01000022_gene1658	4.535e-14	75.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HAM3@91061|Bacilli,1ZD31@1386|Bacillus	91061|Bacilli	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD2_k127_8968961_1	1117379.BABA_19106	7.982e-39	151.0	2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQU5@91061|Bacilli,1ZRA3@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_8968961_2	1294265.JCM21738_1056	5.21e-27	111.0	2E4V8@1|root,32ZPI@2|Bacteria,1VEXD@1239|Firmicutes,4HNT1@91061|Bacilli,1ZIYJ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1657)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1657
HKD2_k127_8968961_3	935836.JAEL01000091_gene5311	1.664e-16	80.0	2DNNI@1|root,32Y9M@2|Bacteria,1VGCK@1239|Firmicutes,4IRXK@91061|Bacilli,1ZRZ0@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1657)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1657
HKD2_k127_8968961_0	1340434.AXVA01000024_gene3851	7.382e-124	403.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1657,DUF421
HKD2_k127_898543_3	1122917.KB899664_gene2981	1.525e-50	184.0	COG1695@1|root,COG1695@2|Bacteria,1VD9H@1239|Firmicutes,4IR5P@91061|Bacilli,276NC@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD2_k127_898543_2	86416.Clopa_1548	2.123e-54	197.0	28PAX@1|root,2ZC3X@2|Bacteria,1V2PI@1239|Firmicutes,24P9U@186801|Clostridia,36RXN@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_898543_1	1443665.JACA01000007_gene197	1.496e-78	281.0	COG0815@1|root,COG0815@2|Bacteria,4NMJK@976|Bacteroidetes,1I4UN@117743|Flavobacteriia,2YH3Q@290174|Aquimarina	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
HKD2_k127_898543_0	224308.BSU40810	3.359e-142	457.0	COG0697@1|root,COG0697@2|Bacteria,1V2GJ@1239|Firmicutes,4HV8D@91061|Bacilli,1ZRP6@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_898543_5	756499.Desde_3259	0.000286	52.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,2648A@186807|Peptococcaceae	186801|Clostridia	KT	Peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4825,Peptidase_M56
HKD2_k127_898543_4	1089548.KI783301_gene805	1.596e-08	65.0	COG4219@1|root,COG4219@2|Bacteria,1VVIQ@1239|Firmicutes	1239|Firmicutes	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9003780_2	926569.ANT_14610	9.13e-55	195.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HKD2_k127_9003780_4	926569.ANT_14620	1.436e-30	124.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD2_k127_9003780_3	926569.ANT_27940	5.391e-51	190.0	COG1647@1|root,COG1647@2|Bacteria,2G73V@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
HKD2_k127_9003780_0	926569.ANT_15680	7.729e-98	327.0	COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi	200795|Chloroflexi	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD2_k127_9053242_2	1499680.CCFE01000011_gene573	6.069e-55	197.0	COG1376@1|root,COG1404@1|root,COG1376@2|Bacteria,COG1404@2|Bacteria,1V6J2@1239|Firmicutes,4HJZH@91061|Bacilli,1ZBKG@1386|Bacillus	91061|Bacilli	O	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,YkuD
HKD2_k127_9053242_1	1131730.BAVI_22148	3.292e-72	265.0	COG4990@1|root,COG5263@1|root,COG4990@2|Bacteria,COG5263@2|Bacteria,1V6DF@1239|Firmicutes,4IPKV@91061|Bacilli,1ZRC4@1386|Bacillus	91061|Bacilli	M	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HKD2_k127_9053242_3	1229783.C273_08936	3.107e-17	96.0	COG1404@1|root,COG2911@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,1UY4R@1239|Firmicutes,4HDRF@91061|Bacilli,4GX2P@90964|Staphylococcaceae	91061|Bacilli	O	PFAM glycoside hydrolase family 39	bhp	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,He_PIG,Peptidase_M30,YSIRK_signal
HKD2_k127_9053242_0	1499680.CCFE01000011_gene569	1.039e-101	341.0	COG4932@1|root,COG4932@2|Bacteria,1UBIW@1239|Firmicutes,4IMYI@91061|Bacilli,1ZM8J@1386|Bacillus	91061|Bacilli	M	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_Y_Y
HKD2_k127_9086676_0	1403313.AXBR01000008_gene561	0.0	1101.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	pbpA	-	-	ko:K21465	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD2_k127_9086676_3	1403313.AXBR01000008_gene560	4.04e-143	460.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus	91061|Bacilli	P	Phosphate	pstS	GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD2_k127_9086676_2	1403313.AXBR01000008_gene559	2.992e-144	462.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,1ZAUU@1386|Bacillus	91061|Bacilli	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD2_k127_9086676_4	1403313.AXBR01000008_gene558	2.686e-142	456.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,1ZDAY@1386|Bacillus	91061|Bacilli	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD2_k127_9086676_1	1403313.AXBR01000008_gene557	6.31e-150	477.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	iSB619.SA_RS06920	ABC_tran
HKD2_k127_9087371_1	666686.B1NLA3E_08555	1.143e-165	524.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,1ZR68@1386|Bacillus	91061|Bacilli	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HKD2_k127_9087371_4	1340434.AXVA01000014_gene554	6.646e-14	73.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZC5H@1386|Bacillus	91061|Bacilli	KT	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
HKD2_k127_9087371_3	666686.B1NLA3E_08590	6.946e-18	84.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZC5H@1386|Bacillus	91061|Bacilli	KT	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
HKD2_k127_9087371_5	666686.B1NLA3E_08590	5.198e-10	60.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZC5H@1386|Bacillus	91061|Bacilli	KT	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
HKD2_k127_9087371_0	1243664.CAVL020000008_gene4080	1.158e-230	721.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	aldHT_2	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD2_k127_9087371_2	1382304.JNIL01000001_gene1399	8.7e-43	164.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli	91061|Bacilli	EH	Acetolactate synthase	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD2_k127_909330_1	1403313.AXBR01000023_gene2676	7.946e-121	394.0	2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,4HCE4@91061|Bacilli,1ZC8T@1386|Bacillus	91061|Bacilli	S	Putative amidase domain	yhbB	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
HKD2_k127_909330_2	1403313.AXBR01000023_gene2675	1.115e-89	297.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,1ZFKH@1386|Bacillus	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	cspR	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HKD2_k127_909330_0	1403313.AXBR01000023_gene2674	7.673e-121	392.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZBQ3@1386|Bacillus	91061|Bacilli	C	Oxidoreductase	nfrA1	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
HKD2_k127_909330_3	1403313.AXBR01000023_gene2664	5.048e-61	211.0	COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus	91061|Bacilli	T	Ser protein kinase	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
HKD2_k127_9096316_2	1340434.AXVA01000016_gene701	2.242e-05	48.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9096316_1	1403313.AXBR01000007_gene492	4.351e-153	486.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,1ZBDS@1386|Bacillus	91061|Bacilli	J	rRNA methylase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HKD2_k127_9096316_0	1403313.AXBR01000007_gene493	0.0	1127.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,1ZBHF@1386|Bacillus	91061|Bacilli	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HKD2_k127_9105770_2	1403313.AXBR01000014_gene2207	1.472e-08	55.0	COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus	91061|Bacilli	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05085	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
HKD2_k127_9105770_1	1403313.AXBR01000014_gene2208	2.11e-104	346.0	COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus	91061|Bacilli	S	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	GO:0003674,GO:0003824,GO:0016787	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
HKD2_k127_9105770_0	1403313.AXBR01000014_gene2209	2.961e-166	524.0	COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,1ZB3B@1386|Bacillus	91061|Bacilli	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD2_k127_9111744_2	1294265.JCM21738_4482	1.102e-39	149.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4IS7E@91061|Bacilli,1ZS1S@1386|Bacillus	91061|Bacilli	E	methionine gamma-lyase	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD2_k127_9111744_0	796606.BMMGA3_13275	9.932e-242	762.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus	91061|Bacilli	T	COG2199 FOG GGDEF domain	ytrP	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
HKD2_k127_9111744_1	1347369.CCAD010000063_gene3973	1.696e-124	404.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,1ZCEB@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD2_k127_9111744_3	189426.PODO_03890	2.379e-21	98.0	2E5FV@1|root,3307J@2|Bacteria,1VGC9@1239|Firmicutes,4HQ3E@91061|Bacilli	91061|Bacilli	S	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD2_k127_9111744_5	935836.JAEL01000031_gene3448	1.333e-06	49.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD2_k127_9114443_3	1403313.AXBR01000008_gene539	1.267e-92	306.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqgX	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HKD2_k127_9114443_9	1403313.AXBR01000008_gene540	1.261e-19	89.0	2ES0W@1|root,306VH@2|Bacteria,1VET3@1239|Firmicutes,4I9TK@91061|Bacilli,1ZK2C@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2759)	yqgW	-	-	-	-	-	-	-	-	-	-	-	DUF2759
HKD2_k127_9114443_5	1403313.AXBR01000008_gene541	1.215e-81	286.0	2BAY9@1|root,324E2@2|Bacteria,1V8TN@1239|Firmicutes,4HJ42@91061|Bacilli,1ZESD@1386|Bacillus	91061|Bacilli	-	-	yqgU	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9114443_1	1403313.AXBR01000008_gene545	2.207e-156	498.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,1ZBV8@1386|Bacillus	91061|Bacilli	G	Glucokinase	glcK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07790	ROK
HKD2_k127_9114443_7	1034347.CAHJ01000039_gene4609	3.544e-25	106.0	COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,1ZISV@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yqgQ	-	-	-	-	-	-	-	-	-	-	-	DUF910
HKD2_k127_9114443_2	1403313.AXBR01000008_gene547	2.385e-94	317.0	28I64@1|root,2Z898@2|Bacteria,1TQX0@1239|Firmicutes,4HF76@91061|Bacilli,1ZEIB@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9114443_0	1403313.AXBR01000008_gene548	7.336e-201	638.0	COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus	91061|Bacilli	O	membrane protein (homolog of Drosophila rhomboid)	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
HKD2_k127_9114443_6	1403313.AXBR01000008_gene552	1.281e-70	244.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,1ZH1W@1386|Bacillus	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HKD2_k127_9114443_8	1294265.JCM21738_2891	2.276e-23	100.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,1ZIUS@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD2_k127_9114443_4	1403313.AXBR01000008_gene553	2.197e-84	283.0	COG3387@1|root,COG3387@2|Bacteria,1U9SF@1239|Firmicutes,4IJZD@91061|Bacilli,1ZETC@1386|Bacillus	91061|Bacilli	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9114443_11	1403313.AXBR01000008_gene554	7.427e-17	81.0	2E4ER@1|root,32Z9X@2|Bacteria,1VGCA@1239|Firmicutes,4HS6U@91061|Bacilli,1ZJ5Y@1386|Bacillus	91061|Bacilli	-	-	yqzD	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
HKD2_k127_9124211_3	1423321.AS29_09245	9.489e-137	441.0	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,1ZCJF@1386|Bacillus	91061|Bacilli	S	tRNA 2-selenouridine synthase	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD2_k127_9124211_0	1243664.CAVL020000005_gene391	1.301e-292	909.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_9124211_1	1211814.CAPG01000048_gene2572	8.822e-239	750.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus	91061|Bacilli	V	ABC transporter	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD2_k127_9124211_2	1034347.CAHJ01000049_gene383	3.133e-209	661.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,1ZB38@1386|Bacillus	91061|Bacilli	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD2_k127_9159221_13	1403313.AXBR01000023_gene2376	4.254e-12	67.0	2EEB8@1|root,3385J@2|Bacteria,1VM15@1239|Firmicutes,4HPJI@91061|Bacilli,1ZJ91@1386|Bacillus	91061|Bacilli	S	Spore germination protein GerPE	gerPE	-	-	ko:K06303	-	-	-	-	ko00000	-	-	-	GerPE
HKD2_k127_9159221_11	1403313.AXBR01000023_gene2377	1.88e-25	106.0	2DP0U@1|root,3302E@2|Bacteria,1VHZ7@1239|Firmicutes,4HNJQ@91061|Bacilli,1ZIWY@1386|Bacillus	91061|Bacilli	S	Spore germination protein gerPA/gerPF	gerPF	-	-	ko:K06299,ko:K06304	-	-	-	-	ko00000	-	-	-	gerPA
HKD2_k127_9159221_0	1403313.AXBR01000023_gene2379	0.0	1810.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	addA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HKD2_k127_9159221_3	1403313.AXBR01000023_gene2381	8.132e-197	619.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus	91061|Bacilli	L	ATP-dependent helicase deoxyribonuclease subunit B	rexB	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
HKD2_k127_9159221_1	1403313.AXBR01000023_gene2381	0.0	1144.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus	91061|Bacilli	L	ATP-dependent helicase deoxyribonuclease subunit B	rexB	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
HKD2_k127_9159221_5	1403313.AXBR01000023_gene2383	6.158e-97	321.0	COG0398@1|root,COG0398@2|Bacteria,1TS5T@1239|Firmicutes,4HDKU@91061|Bacilli,1ZCHZ@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	yhjE	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD2_k127_9159221_10	1174504.AJTN02000235_gene3706	3.285e-50	181.0	2ATJK@1|root,31J3N@2|Bacteria,1V8E1@1239|Firmicutes,4HK5R@91061|Bacilli,1ZH24@1386|Bacillus	91061|Bacilli	-	-	yhjD	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9159221_7	1403313.AXBR01000023_gene2388	8.12e-85	284.0	COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,1ZGB4@1386|Bacillus	91061|Bacilli	K	Competence transcription factor	comK	-	-	ko:K02250	ko02024,map02024	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	ComK
HKD2_k127_9159221_2	1403313.AXBR01000023_gene2391	1.029e-208	656.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus	91061|Bacilli	O	Peptidase M48	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
HKD2_k127_9159221_8	1211814.CAPG01000006_gene204	1.392e-83	281.0	COG1999@1|root,COG1999@2|Bacteria,1VAH3@1239|Firmicutes,4HMIP@91061|Bacilli,1ZCXZ@1386|Bacillus	91061|Bacilli	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD2_k127_9159221_4	1211814.CAPG01000065_gene3143	8.214e-106	347.0	COG0745@1|root,COG0745@2|Bacteria,1V2T8@1239|Firmicutes,4HGQ3@91061|Bacilli,1ZGJX@1386|Bacillus	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_9159221_6	1403313.AXBR01000023_gene2394	1.3e-92	306.0	COG1418@1|root,COG1418@2|Bacteria,1V3UK@1239|Firmicutes,4HH7I@91061|Bacilli,1ZFMK@1386|Bacillus	91061|Bacilli	S	phosphohydrolase	yueE	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
HKD2_k127_9159221_9	1403313.AXBR01000023_gene2396	1.136e-82	277.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,1ZBIZ@1386|Bacillus	91061|Bacilli	H	Lipoate-protein ligase	lplJ	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
HKD2_k127_916254_5	1382358.JHVN01000020_gene1366	1.169e-22	98.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,21WBX@150247|Anoxybacillus	91061|Bacilli	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
HKD2_k127_916254_4	1382358.JHVN01000020_gene1365	3.874e-39	148.0	2DDRJ@1|root,32U1X@2|Bacteria,1VCE7@1239|Firmicutes,4HKC5@91061|Bacilli,21X34@150247|Anoxybacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_916254_2	1403313.AXBR01000009_gene924	1.758e-124	405.0	28I6D@1|root,2ZAC7@2|Bacteria,1UYC6@1239|Firmicutes,4HFH1@91061|Bacilli,1ZC06@1386|Bacillus	91061|Bacilli	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
HKD2_k127_916254_0	1403313.AXBR01000009_gene925	8.225e-200	630.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,1ZDDX@1386|Bacillus	91061|Bacilli	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HKD2_k127_916254_1	1403313.AXBR01000009_gene926	2.307e-167	530.0	COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,1ZBZ7@1386|Bacillus	91061|Bacilli	L	DNA methylase	ytxK	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
HKD2_k127_916254_3	1403313.AXBR01000009_gene928	2.381e-88	293.0	COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,1ZARA@1386|Bacillus	91061|Bacilli	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
HKD2_k127_916254_6	1340434.AXVA01000010_gene5484	3.188e-05	47.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9195563_4	1403313.AXBR01000008_gene522	2.768e-53	190.0	COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,1ZGZX@1386|Bacillus	91061|Bacilli	P	COG0607 Rhodanese-related sulfurtransferase	yqhL	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD2_k127_9195563_1	1403313.AXBR01000008_gene523	1.899e-293	904.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1ZATI@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
HKD2_k127_9195563_2	1174504.AJTN02000225_gene1866	2.715e-234	730.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1ZB0H@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
HKD2_k127_9195563_3	1403313.AXBR01000008_gene525	1.433e-184	582.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HKD2_k127_9195563_0	1403313.AXBR01000008_gene526	1.07e-315	972.0	COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4H9WB@91061|Bacilli,1ZAR5@1386|Bacillus	91061|Bacilli	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	yqhH	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
HKD2_k127_9195563_6	1132442.KB889752_gene2223	3.259e-49	185.0	2CH5D@1|root,2Z821@2|Bacteria,1TS45@1239|Firmicutes,4HCE9@91061|Bacilli,1ZAXP@1386|Bacillus	91061|Bacilli	S	Bacterial protein YqhG of unknown function	yqhG	-	-	-	-	-	-	-	-	-	-	-	YqhG
HKD2_k127_9195563_11	1169144.KB910946_gene3715	2.371e-13	71.0	2EKZB@1|root,33ENU@2|Bacteria,1VM73@1239|Firmicutes,4HR7F@91061|Bacilli,1ZJY6@1386|Bacillus	91061|Bacilli	S	YqzE-like protein	yqzE	-	-	-	-	-	-	-	-	-	-	-	YqzE
HKD2_k127_9195563_5	935837.JAEK01000001_gene2259	2.407e-49	180.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,1ZHX4@1386|Bacillus	91061|Bacilli	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HKD2_k127_9195563_7	1403313.AXBR01000008_gene529	1.146e-38	149.0	COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli,1ZIZV@1386|Bacillus	91061|Bacilli	U	COG4940 Competence protein ComGF	comGF	-	-	ko:K02248	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComGF,N_methyl
HKD2_k127_9195563_10	1307436.PBF_11807	4.897e-16	83.0	COG4970@1|root,COG4970@2|Bacteria,1VBS8@1239|Firmicutes,4HKPK@91061|Bacilli,1ZJ1Q@1386|Bacillus	91061|Bacilli	NU	COG2165 Type II secretory pathway, pseudopilin PulG	comGD	-	-	ko:K02246	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	N_methyl
HKD2_k127_9195563_8	1403313.AXBR01000008_gene532	2.921e-35	136.0	COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,1ZIXK@1386|Bacillus	91061|Bacilli	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	N_methyl
HKD2_k127_9283426_2	1117379.BABA_23148	6.796e-100	331.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HGHY@91061|Bacilli,1ZBY0@1386|Bacillus	91061|Bacilli	S	MgtC SapB transporter	sapB	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
HKD2_k127_9283426_0	1117379.BABA_07691	8.498e-120	393.0	COG1277@1|root,COG1277@2|Bacteria,1TT9E@1239|Firmicutes,4HE5W@91061|Bacilli,1ZDPM@1386|Bacillus	91061|Bacilli	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
HKD2_k127_9283426_1	1034347.CAHJ01000039_gene4735	3.025e-111	364.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,1ZB4N@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD2_k127_9283898_3	1403313.AXBR01000017_gene3613	1.591e-99	325.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZBQI@1386|Bacillus	91061|Bacilli	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD2_k127_9283898_1	1384057.CD33_08265	2.651e-135	439.0	COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,3IYWZ@400634|Lysinibacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HKD2_k127_9283898_0	1499680.CCFE01000025_gene3260	1.306e-275	854.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_9283898_4	1134413.ANNK01000155_gene3662	7.639e-61	212.0	COG2764@1|root,COG2764@2|Bacteria,1V3WE@1239|Firmicutes,4HHHS@91061|Bacilli,1ZGHJ@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
HKD2_k127_9283898_2	1403313.AXBR01000017_gene3612	5.867e-122	394.0	2B1Y6@1|root,31UEI@2|Bacteria,1V85P@1239|Firmicutes,4HJP9@91061|Bacilli,1ZG3J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD2_k127_9307109_1	180332.JTGN01000012_gene325	7.294e-118	388.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
HKD2_k127_9307109_0	1348908.KI518630_gene148	2.063e-164	523.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,1ZCD4@1386|Bacillus	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HKD2_k127_9307109_2	109871.XP_006683187.1	8.66e-107	350.0	COG0476@1|root,KOG2017@2759|Eukaryota,38E2S@33154|Opisthokonta,3NZDJ@4751|Fungi	2759|Eukaryota	H	Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.80,2.8.1.11	ko:K11996,ko:K22132	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000,ko03016,ko04121	-	-	-	MoeA_C,Rhodanese,ThiF
HKD2_k127_9324507_7	1121403.AUCV01000029_gene2729	1.68e-58	209.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria,2MNIH@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Isochorismatase family	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HKD2_k127_9324507_8	1403313.AXBR01000005_gene2060	5.326e-39	149.0	COG1522@1|root,COG1522@2|Bacteria,1V45K@1239|Firmicutes,4HH2H@91061|Bacilli,1ZGIJ@1386|Bacillus	91061|Bacilli	K	transcriptional	lrpB	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD2_k127_9324507_10	1121091.AUMP01000009_gene4059	5.285e-11	63.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HIUZ@91061|Bacilli	91061|Bacilli	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD2_k127_9324507_6	1536770.R50345_29910	6.291e-62	217.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli,26XT9@186822|Paenibacillaceae	91061|Bacilli	P	Alkylphosphonate utilization protein	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
HKD2_k127_9324507_3	1132442.KB889752_gene3501	2.778e-95	314.0	COG5516@1|root,COG5516@2|Bacteria,1VN58@1239|Firmicutes,4HS14@91061|Bacilli,1ZFS8@1386|Bacillus	91061|Bacilli	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
HKD2_k127_9324507_2	1132442.KB889752_gene3502	1.441e-102	335.0	COG3448@1|root,COG3448@2|Bacteria,1V4K3@1239|Firmicutes,4HH5F@91061|Bacilli,1ZFJ1@1386|Bacillus	91061|Bacilli	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
HKD2_k127_9324507_4	666686.B1NLA3E_09875	4.895e-78	263.0	COG0454@1|root,COG0456@2|Bacteria,1V6S5@1239|Firmicutes,4HJJY@91061|Bacilli,1ZFYC@1386|Bacillus	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD2_k127_9324507_9	558169.AGAV01000005_gene2209	1.062e-34	138.0	2E4P1@1|root,32ZHT@2|Bacteria,1VF8Y@1239|Firmicutes,4HQ3Y@91061|Bacilli	91061|Bacilli	S	Family of unknown function (DUF5392)	ywnF	-	-	-	-	-	-	-	-	-	-	-	DUF5392
HKD2_k127_9324507_1	1132442.KB889752_gene1888	9.056e-105	342.0	COG0431@1|root,COG0431@2|Bacteria,1TP8I@1239|Firmicutes,4HACX@91061|Bacilli,1ZCIR@1386|Bacillus	91061|Bacilli	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD2_k127_9324507_12	43354.JOIJ01000001_gene77	2.409e-05	48.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4DXG6@85010|Pseudonocardiales	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_9324507_0	1347086.CCBA010000011_gene1615	5.93e-152	487.0	COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,1ZCXC@1386|Bacillus	91061|Bacilli	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
HKD2_k127_9324507_5	1034347.CAHJ01000006_gene2511	3.113e-66	232.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,1ZDDZ@1386|Bacillus	91061|Bacilli	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HKD2_k127_9324941_0	1403313.AXBR01000006_gene83	1.527e-181	574.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus	91061|Bacilli	E	Acetylornithine deacetylase	yodQ	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD2_k127_9324941_2	1174504.AJTN02000222_gene1428	1.562e-94	314.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus	91061|Bacilli	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	atoA	-	2.8.3.8,2.8.3.9	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_9324941_1	1403313.AXBR01000006_gene85	3.184e-106	349.0	COG1788@1|root,COG1788@2|Bacteria,1TSZT@1239|Firmicutes,4HDJG@91061|Bacilli,1ZQEH@1386|Bacillus	91061|Bacilli	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	atoD	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD2_k127_9324941_3	1403313.AXBR01000006_gene86	5.075e-54	193.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HD8E@91061|Bacilli,1ZAWS@1386|Bacillus	91061|Bacilli	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	yodT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HKD2_k127_9331208_9	1117379.BABA_05291	1.203e-31	124.0	COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,1ZGHR@1386|Bacillus	91061|Bacilli	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD2_k127_9331208_5	1131730.BAVI_10637	4.019e-137	439.0	COG1028@1|root,COG1028@2|Bacteria,1TQZW@1239|Firmicutes,4HAS8@91061|Bacilli,1ZBWH@1386|Bacillus	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD2_k127_9331208_2	1499680.CCFE01000021_gene2211	3.925e-196	617.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HC4S@91061|Bacilli,1ZQZX@1386|Bacillus	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	amacr	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HKD2_k127_9331208_3	1131730.BAVI_10627	2.008e-182	577.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,1ZEPG@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.3.8.7	ko:K00249,ko:K11731	ko00071,ko00280,ko00281,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00281,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R08089	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD2_k127_9331208_0	1131730.BAVI_10622	9.082e-269	837.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus	91061|Bacilli	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_8,Sigma54_activat
HKD2_k127_9331208_1	666686.B1NLA3E_08935	3.782e-202	634.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,1ZCBB@1386|Bacillus	91061|Bacilli	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT_4
HKD2_k127_9331208_6	1121091.AUMP01000013_gene3284	1.142e-119	389.0	COG0778@1|root,COG0778@2|Bacteria,1UY9E@1239|Firmicutes,4HBU8@91061|Bacilli	91061|Bacilli	C	Cob(II)yrinic acid a,c-diamide reductase	bluB	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
HKD2_k127_9331208_4	1405.DJ92_5191	1.369e-166	533.0	COG0477@1|root,COG2814@2|Bacteria,1TRXM@1239|Firmicutes,4HCK1@91061|Bacilli,1ZPZJ@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
HKD2_k127_9331208_7	1403313.AXBR01000005_gene1763	5.571e-65	226.0	298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,1ZH6F@1386|Bacillus	91061|Bacilli	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
HKD2_k127_9331208_8	1274524.BSONL12_02589	4.873e-39	146.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,1ZBCQ@1386|Bacillus	91061|Bacilli	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU08790	ThiC-associated,ThiC_Rad_SAM
HKD2_k127_9333771_0	665959.HMPREF1013_05270	0.0	1853.0	COG1674@1|root,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,4H9QM@91061|Bacilli,1ZDSN@1386|Bacillus	91061|Bacilli	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	essC	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N
HKD2_k127_9333771_1	1196031.ALEG01000042_gene2322	9.244e-135	443.0	COG4499@1|root,COG4499@2|Bacteria,1UY6F@1239|Firmicutes,4H9W3@91061|Bacilli,1ZCXX@1386|Bacillus	91061|Bacilli	S	WXG100 protein secretion system (Wss), protein YukC	essB	-	-	-	-	-	-	-	-	-	-	-	YukC
HKD2_k127_9333771_3	265729.GS18_0216245	1.522e-34	133.0	COG5417@1|root,COG5417@2|Bacteria,1VG9I@1239|Firmicutes,4HPXH@91061|Bacilli,1ZHKG@1386|Bacillus	91061|Bacilli	S	WXG100 protein secretion system (Wss), protein YukD	yukD	-	-	-	-	-	-	-	-	-	-	-	YukD
HKD2_k127_9333771_4	935837.JAEK01000065_gene3935	2.815e-31	125.0	COG4842@1|root,COG4842@2|Bacteria,1VACX@1239|Firmicutes,4HKCR@91061|Bacilli,1ZH2G@1386|Bacillus	91061|Bacilli	S	Belongs to the WXG100 family	esxA	-	-	-	-	-	-	-	-	-	-	-	WXG100
HKD2_k127_9333771_2	406124.ACPC01000009_gene1455	2.146e-64	233.0	2CA56@1|root,2Z93A@2|Bacteria,1TSPR@1239|Firmicutes,4HAN6@91061|Bacilli,1ZEQ5@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
HKD2_k127_9336632_0	1403313.AXBR01000021_gene3247	1.379e-207	648.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,1ZBE0@1386|Bacillus	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD2_k127_9336632_1	1403313.AXBR01000021_gene3246	1.559e-194	608.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,1ZBJ1@1386|Bacillus	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05355,iYO844.BSU14590	Transket_pyr,Transketolase_C
HKD2_k127_9336632_2	1403313.AXBR01000021_gene3245	2.156e-169	537.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,1ZAQR@1386|Bacillus	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD2_k127_9339360_3	1403313.AXBR01000021_gene3064	3.42e-139	448.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus	91061|Bacilli	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD2_k127_9339360_0	1403313.AXBR01000021_gene3065	1.886e-313	965.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,1ZD7M@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
HKD2_k127_9339360_1	1403313.AXBR01000021_gene3066	1.638e-229	715.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,1ZCPQ@1386|Bacillus	91061|Bacilli	M	zinc metalloprotease	rasP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
HKD2_k127_9339360_2	1174504.AJTN02000031_gene898	1.018e-191	603.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,1ZC3I@1386|Bacillus	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
HKD2_k127_9339360_4	1403313.AXBR01000021_gene3068	1.251e-81	274.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,1ZBWF@1386|Bacillus	91061|Bacilli	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
HKD2_k127_9354324_3	1174504.AJTN02000189_gene715	1.045e-75	256.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,1ZAQH@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD2_k127_9354324_1	1174504.AJTN02000189_gene714	2.077e-123	398.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HA3V@91061|Bacilli,1ZB23@1386|Bacillus	91061|Bacilli	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	degU	-	-	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	M00478	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
HKD2_k127_9354324_0	1403313.AXBR01000026_gene5146	4.079e-176	559.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HAUU@91061|Bacilli,1ZDAA@1386|Bacillus	91061|Bacilli	T	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
HKD2_k127_9354324_2	1403313.AXBR01000026_gene5147	4.16e-99	327.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,1ZAXD@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1949)	yvyE	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF1949,UPF0029
HKD2_k127_9366581_3	1403313.AXBR01000010_gene956	5.233e-28	115.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus	91061|Bacilli	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	iYO844.BSU29710	Hist_deacetyl
HKD2_k127_9366581_2	1403313.AXBR01000010_gene955	9.535e-95	314.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,1ZBNZ@1386|Bacillus	91061|Bacilli	S	Acetoin utilization protein AcuB	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
HKD2_k127_9366581_1	1403313.AXBR01000010_gene954	2.556e-108	353.0	COG0454@1|root,COG0454@2|Bacteria,1TSEY@1239|Firmicutes,4HA1V@91061|Bacilli,1ZANI@1386|Bacillus	91061|Bacilli	K	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue	acuA	GO:0001101,GO:0003674,GO:0003824,GO:0006066,GO:0006355,GO:0006950,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009267,GO:0009605,GO:0009847,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010034,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016407,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019152,GO:0019219,GO:0019222,GO:0019751,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032502,GO:0033554,GO:0034077,GO:0034078,GO:0034311,GO:0034313,GO:0042149,GO:0042180,GO:0042182,GO:0042221,GO:0042594,GO:0042844,GO:0042846,GO:0043894,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045013,GO:0045014,GO:0045149,GO:0045150,GO:0045892,GO:0045934,GO:0045990,GO:0046015,GO:0046164,GO:0046174,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0061984,GO:0061985,GO:0061986,GO:0065007,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071311,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1901700,GO:1901701,GO:1902652,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K04766	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD2_k127_9366581_0	1403313.AXBR01000010_gene953	0.0	1048.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZBDX@1386|Bacillus	91061|Bacilli	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD2_k127_9367550_7	666686.B1NLA3E_08675	1.14e-58	205.0	COG0247@1|root,COG0247@2|Bacteria,1VUZJ@1239|Firmicutes,4HVNI@91061|Bacilli	91061|Bacilli	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
HKD2_k127_9367550_5	666686.B1NLA3E_08670	1.925e-83	277.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,4HNW0@91061|Bacilli,1ZNK8@1386|Bacillus	91061|Bacilli	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HKD2_k127_9367550_9	1121091.AUMP01000031_gene1434	2.655e-51	188.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,4HJUK@91061|Bacilli	91061|Bacilli	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
HKD2_k127_9367550_1	1340434.AXVA01000008_gene3625	2.387e-245	766.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_9367550_10	666686.B1NLA3E_12005	2.571e-40	153.0	COG1309@1|root,COG1309@2|Bacteria,1TP0U@1239|Firmicutes,4HE9Q@91061|Bacilli,1ZBMJ@1386|Bacillus	91061|Bacilli	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_9367550_11	1347086.CCBA010000009_gene1388	1.516e-12	68.0	COG1309@1|root,COG1309@2|Bacteria,1TP0U@1239|Firmicutes,4HE9Q@91061|Bacilli,1ZBMJ@1386|Bacillus	91061|Bacilli	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD2_k127_9367550_6	562970.Btus_0243	2.59e-61	218.0	COG4194@1|root,COG5658@1|root,COG4194@2|Bacteria,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,4HJDZ@91061|Bacilli,278K6@186823|Alicyclobacillaceae	91061|Bacilli	S	SdpI/YhfL protein family	yvaZ	GO:0008150,GO:0009636,GO:0042221,GO:0050896	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
HKD2_k127_9367550_4	1132442.KB889752_gene3851	1.327e-168	541.0	COG4320@1|root,COG4320@2|Bacteria,1UCBA@1239|Firmicutes,4HBCI@91061|Bacilli,1ZFD5@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DUF2252
HKD2_k127_9367550_0	1356854.N007_12415	3.979e-304	936.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli	91061|Bacilli	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yhcX	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
HKD2_k127_9367550_8	1243664.CAVL020000058_gene4435	8.921e-53	188.0	COG2329@1|root,COG2329@2|Bacteria,1VBU1@1239|Firmicutes,4HKIH@91061|Bacilli,1ZH5T@1386|Bacillus	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	isdG	-	1.14.99.48	ko:K07145	ko00860,ko01110,map00860,map01110	-	R10468,R10510	RC03185	ko00000,ko00001,ko01000	-	-	-	ABM
HKD2_k127_9367550_2	1243664.CAVL020000047_gene2329	7.653e-196	617.0	COG3135@1|root,COG3135@2|Bacteria,1UFIU@1239|Firmicutes,4HE6P@91061|Bacilli,1ZB1R@1386|Bacillus	91061|Bacilli	Q	Benzoate membrane transport protein	-	-	-	-	-	-	-	-	-	-	-	-	BenE
HKD2_k127_9367550_3	1196029.ALIM01000034_gene1837	1.222e-189	602.0	COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HDUQ@91061|Bacilli,1ZC8H@1386|Bacillus	91061|Bacilli	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	ko:K05548	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4,Sugar_tr
HKD2_k127_9381113_1	586413.CCDL010000001_gene1252	1.16e-83	281.0	2BXP4@1|root,2ZBZG@2|Bacteria,1V1ZR@1239|Firmicutes,4HCWM@91061|Bacilli,23KYF@182709|Oceanobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SAP
HKD2_k127_9381113_0	1403313.AXBR01000004_gene1659	2.522e-296	922.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus	91061|Bacilli	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD2_k127_9382575_6	1403313.AXBR01000008_gene642	5.055e-31	122.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,1ZB7T@1386|Bacillus	91061|Bacilli	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HKD2_k127_9382575_1	1403313.AXBR01000008_gene643	4.269e-96	318.0	COG0500@1|root,COG2226@2|Bacteria,1V3T6@1239|Firmicutes,4HHF1@91061|Bacilli,1ZFN7@1386|Bacillus	91061|Bacilli	Q	Could be a S-adenosyl-L-methionine-dependent methyltransferase	yrrT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00609	R10404	RC00003	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
HKD2_k127_9382575_8	1174504.AJTN02000236_gene484	2.922e-23	100.0	2E6WR@1|root,331G7@2|Bacteria,1VHCS@1239|Firmicutes,4HQVN@91061|Bacilli,1ZIT5@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2536)	yrzA	-	-	-	-	-	-	-	-	-	-	-	DUF2536
HKD2_k127_9382575_4	935837.JAEK01000016_gene1244	1.007e-63	220.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HIEE@91061|Bacilli,1ZQY1@1386|Bacillus	91061|Bacilli	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD2_k127_9382575_2	935837.JAEK01000015_gene5061	1.657e-71	242.0	COG0251@1|root,COG0251@2|Bacteria,1V58T@1239|Firmicutes,4HVNR@91061|Bacilli,1ZGWV@1386|Bacillus	91061|Bacilli	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HKD2_k127_9382575_9	561230.PC1_2136	7.096e-22	100.0	2E8SS@1|root,3333I@2|Bacteria,1NF8M@1224|Proteobacteria,1SJ9Y@1236|Gammaproteobacteria,1MSH9@122277|Pectobacterium	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9382575_7	1461582.BN1048_00957	1.373e-30	124.0	2FEWC@1|root,346V6@2|Bacteria,1W098@1239|Firmicutes,4HZDS@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9382575_3	1403313.AXBR01000008_gene644	1.283e-65	229.0	2BJ57@1|root,32DEE@2|Bacteria,1V93H@1239|Firmicutes,4HN71@91061|Bacilli,1ZH00@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1510)	yrrS	-	-	-	-	-	-	-	-	-	-	-	DUF1510
HKD2_k127_9382575_0	1403313.AXBR01000008_gene645	1.818e-278	865.0	COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus	91061|Bacilli	M	Penicillin-binding Protein	pbpI	-	-	ko:K21468	-	-	-	-	ko00000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD2_k127_9382575_5	796606.BMMGA3_12205	7.923e-59	205.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD2_k127_9382712_1	1385513.N780_01055	3.889e-57	201.0	COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,2YAGY@289201|Pontibacillus	91061|Bacilli	S	General stress protein	ydaG	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyrid_ox_like
HKD2_k127_9382712_0	1403313.AXBR01000005_gene1897	6.922e-80	270.0	COG0847@1|root,COG0847@2|Bacteria,1VDT3@1239|Firmicutes,4HWEJ@91061|Bacilli,1ZEA7@1386|Bacillus	91061|Bacilli	L	COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HKD2_k127_9382712_2	1461580.CCAS010000013_gene1707	4.402e-20	90.0	2E5UW@1|root,330J3@2|Bacteria,1VFMQ@1239|Firmicutes,4HPRZ@91061|Bacilli,1ZIYY@1386|Bacillus	91061|Bacilli	S	Small acid-soluble spore protein H family	sspH	-	-	ko:K06425	-	-	-	-	ko00000	-	-	-	SspH
HKD2_k127_9401577_11	1385514.N782_03495	7.671e-05	46.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9401577_5	1403313.AXBR01000021_gene3193	6.038e-61	212.0	2CC47@1|root,2ZQ3T@2|Bacteria,1V53R@1239|Firmicutes,4HIC8@91061|Bacilli,1ZGZC@1386|Bacillus	91061|Bacilli	S	Methylthioribose kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9401577_6	1243664.CAVL020000025_gene1578	1.155e-46	187.0	2D69E@1|root,32TKR@2|Bacteria,1VCRS@1239|Firmicutes,4HMFA@91061|Bacilli,1ZAXR@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
HKD2_k127_9401577_3	1403313.AXBR01000021_gene3192	1.86e-93	310.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,1ZFNI@1386|Bacillus	91061|Bacilli	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD2_k127_9401577_4	1403313.AXBR01000021_gene3191	3.106e-78	263.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,1ZFNZ@1386|Bacillus	91061|Bacilli	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD2_k127_9401577_1	1340434.AXVA01000003_gene1708	4.392e-148	481.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus	91061|Bacilli	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
HKD2_k127_9401577_2	1403313.AXBR01000021_gene3188	1.559e-131	423.0	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,1ZBCG@1386|Bacillus	91061|Bacilli	S	esterase of the alpha-beta hydrolase superfamily	ylbK	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HKD2_k127_9401577_0	1403313.AXBR01000021_gene3187	3.85e-158	504.0	COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,1ZAW6@1386|Bacillus	91061|Bacilli	T	Belongs to the peptidase S16 family	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
HKD2_k127_9401577_7	1384057.CD33_11680	1.842e-23	101.0	2EAS4@1|root,334U7@2|Bacteria,1VG99@1239|Firmicutes,4HQI1@91061|Bacilli,3IYP2@400634|Lysinibacillus	91061|Bacilli	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HKD2_k127_9401577_8	1403313.AXBR01000021_gene3186	9.428e-16	78.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,1ZC63@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0348 family	ylbM	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
HKD2_k127_9401613_4	1340434.AXVA01000016_gene701	0.0002962	43.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9401613_1	1403313.AXBR01000007_gene489	2.532e-222	694.0	COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,4H9TW@91061|Bacilli,1ZB04@1386|Bacillus	91061|Bacilli	M	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S55
HKD2_k127_9401613_0	1403313.AXBR01000007_gene490	5.388e-296	916.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,1ZC8B@1386|Bacillus	91061|Bacilli	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HKD2_k127_9401613_2	1403313.AXBR01000007_gene491	3.242e-84	280.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,1ZFJ8@1386|Bacillus	91061|Bacilli	K	Regulates arginine biosynthesis genes	argR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
HKD2_k127_9421558_0	1403313.AXBR01000002_gene4112	3.517e-189	595.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus	91061|Bacilli	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
HKD2_k127_9421558_1	1403313.AXBR01000002_gene4113	2.996e-171	542.0	COG1988@1|root,COG1988@2|Bacteria,1TQFC@1239|Firmicutes,4H9PU@91061|Bacilli,1ZBEI@1386|Bacillus	91061|Bacilli	S	membrane-bound metal-dependent	yfhP	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD2_k127_9421558_5	1403313.AXBR01000002_gene4114	1.054e-34	134.0	2CEK7@1|root,330II@2|Bacteria,1VFTN@1239|Firmicutes,4HNJY@91061|Bacilli,1ZI0N@1386|Bacillus	91061|Bacilli	S	WVELL protein	yfhJ	-	-	-	-	-	-	-	-	-	-	-	WVELL
HKD2_k127_9421558_6	1033734.CAET01000052_gene1495	3.512e-17	84.0	2ERTV@1|root,33JD2@2|Bacteria,1VG3A@1239|Firmicutes,4HPKX@91061|Bacilli,1ZIVJ@1386|Bacillus	91061|Bacilli	S	reproduction	sspK	-	-	ko:K06428	-	-	-	-	ko00000	-	-	-	SspK
HKD2_k127_9421558_10	1033734.CAET01000052_gene1496	1.681e-05	48.0	2EMC3@1|root,33F12@2|Bacteria,1VQ0Z@1239|Firmicutes,4HRZ4@91061|Bacilli,1ZKAA@1386|Bacillus	91061|Bacilli	S	YpzG-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YpzG
HKD2_k127_9421558_4	1403313.AXBR01000002_gene4115	8.036e-51	181.0	2C8IW@1|root,32PGC@2|Bacteria,1VADG@1239|Firmicutes,4HNM3@91061|Bacilli,1ZH1I@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1811)	yfhH	-	-	-	-	-	-	-	-	-	-	-	DUF1811
HKD2_k127_9421558_3	1403313.AXBR01000002_gene4116	1.149e-114	374.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,1ZC8N@1386|Bacillus	91061|Bacilli	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HKD2_k127_9421558_2	1403313.AXBR01000002_gene4117	1.455e-128	417.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus	91061|Bacilli	S	nucleoside-diphosphate sugar epimerase	yfhF	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
HKD2_k127_9421558_7	1403313.AXBR01000002_gene4118	1.226e-07	54.0	2DJQF@1|root,306WX@2|Bacteria,1U0IF@1239|Firmicutes,4I9X1@91061|Bacilli,1ZJCB@1386|Bacillus	91061|Bacilli	S	YfhD-like protein	yfhD	-	-	-	-	-	-	-	-	-	-	-	YfhD
HKD2_k127_9456939_20	1403313.AXBR01000023_gene2438	2.84e-11	66.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1ZB1W@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0754 family	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD2_k127_9456939_10	1174504.AJTN02000260_gene1615	1.82e-122	409.0	COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus	91061|Bacilli	HJ	YheC/D like ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD2_k127_9456939_8	1403313.AXBR01000023_gene2441	9.956e-130	423.0	COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus	91061|Bacilli	HJ	YheC/D like ATP-grasp	yheC	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD2_k127_9456939_4	1403313.AXBR01000023_gene2442	8.787e-225	703.0	COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus	91061|Bacilli	HJ	YheC/D like ATP-grasp	yheD	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD2_k127_9456939_11	1403313.AXBR01000023_gene2443	7.998e-118	390.0	COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus	91061|Bacilli	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD2_k127_9456939_18	1403313.AXBR01000023_gene2444	5.489e-25	105.0	2E3WD@1|root,32YTI@2|Bacteria,1VGKG@1239|Firmicutes,4HSKD@91061|Bacilli,1ZIY3@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5342)	yheE	-	-	-	-	-	-	-	-	-	-	-	DUF5342
HKD2_k127_9456939_16	1174504.AJTN02000001_gene2831	1.522e-34	133.0	2EH16@1|root,33AT6@2|Bacteria,1VKV6@1239|Firmicutes,4HQNG@91061|Bacilli,1ZJ5S@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9456939_1	1403313.AXBR01000023_gene2455	3.35e-273	843.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,1ZS23@1386|Bacillus	91061|Bacilli	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09430	FumaraseC_C,Lyase_1
HKD2_k127_9456939_6	1403313.AXBR01000023_gene2456	3.578e-201	631.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	metB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HKD2_k127_9456939_5	1403313.AXBR01000023_gene2457	1.729e-205	644.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	metC	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU11880	Cys_Met_Meta_PP
HKD2_k127_9456939_15	666686.B1NLA3E_19090	6.574e-39	149.0	COG0196@1|root,COG0196@2|Bacteria,1VXBN@1239|Firmicutes,4HXKJ@91061|Bacilli,1ZHUP@1386|Bacillus	91061|Bacilli	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavokinase
HKD2_k127_9456939_17	1403313.AXBR01000023_gene2462	1.682e-34	136.0	2BBAB@1|root,324T2@2|Bacteria,1UAI4@1239|Firmicutes,4IKWM@91061|Bacilli,1ZI3C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9456939_0	1403313.AXBR01000023_gene2463	7.078e-315	976.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	pbpA	-	-	ko:K21465	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD2_k127_9456939_14	1196029.ALIM01000049_gene4515	1.074e-49	181.0	COG2030@1|root,COG2030@2|Bacteria,1VFE5@1239|Firmicutes,4HHCB@91061|Bacilli,1ZHGT@1386|Bacillus	91061|Bacilli	I	N-terminal half of MaoC dehydratase	ydeM1	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HKD2_k127_9456939_12	755731.Clo1100_0203	2.002e-85	304.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36H1K@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal,sCache_3_2,sCache_3_3
HKD2_k127_9456939_3	665959.HMPREF1013_03244	1.619e-238	746.0	COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli,1ZS1D@1386|Bacillus	91061|Bacilli	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD2_k127_9456939_21	1033734.CAET01000026_gene921	4.705e-08	55.0	2BF2Y@1|root,328UZ@2|Bacteria,1UB68@1239|Firmicutes,4IMIW@91061|Bacilli,1ZK99@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9456939_9	666686.B1NLA3E_12475	1.687e-123	400.0	COG1587@1|root,COG1587@2|Bacteria,1V0K1@1239|Firmicutes,4HFWP@91061|Bacilli,1ZCRM@1386|Bacillus	91061|Bacilli	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD2_k127_9456939_13	1403313.AXBR01000023_gene2464	5.673e-59	208.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,4HJC8@91061|Bacilli,1ZI6W@1386|Bacillus	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD2_k127_9456939_2	1403313.AXBR01000023_gene2465	3.67e-271	839.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1ZB20@1386|Bacillus	91061|Bacilli	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HKD2_k127_9456939_7	1403313.AXBR01000023_gene2466	4.516e-142	453.0	COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,4H9P0@91061|Bacilli,1ZERN@1386|Bacillus	91061|Bacilli	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HKD2_k127_946075_4	1117379.BABA_22883	3.69e-14	72.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,4HDDP@91061|Bacilli,1ZC2G@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	yycG_2	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD2_k127_946075_2	1117379.BABA_22878	1.769e-118	386.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,4HAX9@91061|Bacilli,1ZBV9@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD2_k127_946075_0	666686.B1NLA3E_07800	2.266e-217	683.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,1ZCMY@1386|Bacillus	91061|Bacilli	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD2_k127_946075_1	1461580.CCAS010000016_gene1987	2.924e-120	389.0	COG2042@1|root,COG3376@2|Bacteria,1U4YZ@1239|Firmicutes,4IEY4@91061|Bacilli,1ZKA1@1386|Bacillus	91061|Bacilli	U	High-affinity nickel-transport protein	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
HKD2_k127_9468756_2	1243664.CAVL020000049_gene5083	1.607e-159	515.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,1ZBJC@1386|Bacillus	91061|Bacilli	V	ABC transporter (permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD2_k127_9468756_3	1403313.AXBR01000009_gene785	6.624e-99	339.0	COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus	91061|Bacilli	M	stage VI sporulation protein D	spoVID	GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117	-	ko:K06417	-	-	-	-	ko00000	-	-	-	LysM
HKD2_k127_9468756_1	1403313.AXBR01000009_gene784	1.388e-160	512.0	COG2334@1|root,COG2334@2|Bacteria,1V54J@1239|Firmicutes,4HH2K@91061|Bacilli,1ZB97@1386|Bacillus	91061|Bacilli	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	ysxE	-	-	-	-	-	-	-	-	-	-	-	APH
HKD2_k127_9468756_4	1307436.PBF_21248	5.986e-10	61.0	2ESUV@1|root,33KD9@2|Bacteria,1VP5F@1239|Firmicutes,4HSYB@91061|Bacilli,1ZIWU@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9468756_0	1403313.AXBR01000009_gene782	2.611e-191	599.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD2_k127_9515906_1	1499680.CCFE01000011_gene569	5.017e-45	169.0	COG4932@1|root,COG4932@2|Bacteria,1UBIW@1239|Firmicutes,4IMYI@91061|Bacilli,1ZM8J@1386|Bacillus	91061|Bacilli	M	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_Y_Y
HKD2_k127_9515906_0	1122915.AUGY01000093_gene3627	1.28e-182	575.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,26UJA@186822|Paenibacillaceae	91061|Bacilli	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HKD2_k127_9515906_2	324057.Pjdr2_4147	6.18e-07	51.0	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,26UGA@186822|Paenibacillaceae	91061|Bacilli	S	tRNA 2-selenouridine synthase	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD2_k127_9518928_0	755731.Clo1100_1077	9.44e-165	532.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia,36F38@31979|Clostridiaceae	186801|Clostridia	G	hydrolase family 65, central catalytic	-	-	2.4.1.230,2.4.1.282	ko:K10231,ko:K18784	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
HKD2_k127_953315_7	1196031.ALEG01000028_gene4273	9.646e-20	90.0	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1V6Q8@1239|Firmicutes,4HKAY@91061|Bacilli,1ZDSB@1386|Bacillus	91061|Bacilli	M	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D,LysM
HKD2_k127_953315_6	1295642.H839_08963	1.304e-38	148.0	COG1633@1|root,COG1633@2|Bacteria,1V9AF@1239|Firmicutes,4HIP7@91061|Bacilli,1WGYK@129337|Geobacillus	91061|Bacilli	S	Rubrerythrin	yhjR	-	-	-	-	-	-	-	-	-	-	-	DUF2202,Rubrerythrin
HKD2_k127_953315_2	1403313.AXBR01000002_gene4340	8.371e-153	493.0	COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K02491,ko:K13533	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA,LytTR,MASE3,PAS,PAS_3,PAS_4,PAS_9
HKD2_k127_953315_0	1403313.AXBR01000002_gene4339	1.268e-186	590.0	COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,1ZC9I@1386|Bacillus	91061|Bacilli	L	COG0513 Superfamily II DNA and RNA helicases	yfmL	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HKD2_k127_953315_3	1403313.AXBR01000002_gene4269	6.836e-99	327.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,1ZBB9@1386|Bacillus	91061|Bacilli	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08950,iYO844.BSU23270	Lum_binding
HKD2_k127_953315_4	1403313.AXBR01000002_gene4268	1.483e-93	310.0	COG0108@1|root,COG0108@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,1ZBF9@1386|Bacillus	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
HKD2_k127_953315_5	1403313.AXBR01000002_gene4267	7.825e-85	282.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,1ZFJ6@1386|Bacillus	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
HKD2_k127_953315_1	1403313.AXBR01000002_gene4266	1.429e-179	569.0	COG2404@1|root,COG2404@2|Bacteria,1TQPZ@1239|Firmicutes,4HCSM@91061|Bacilli,1ZCH8@1386|Bacillus	91061|Bacilli	S	phosphohydrolase (DHH superfamily)	yngD	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
HKD2_k127_9609112_0	326427.Cagg_2907	1.999e-67	241.0	COG1172@1|root,COG1172@2|Bacteria,2G6A4@200795|Chloroflexi,377ZT@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HKD2_k127_9609112_2	1007103.AFHW01000141_gene1236	1.038e-48	187.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,26R5U@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HKD2_k127_9609112_1	926550.CLDAP_06170	9.389e-61	218.0	COG1129@1|root,COG1129@2|Bacteria,2G8AK@200795|Chloroflexi	200795|Chloroflexi	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HKD2_k127_9609112_3	103733.JNYO01000060_gene8738	1.401e-17	93.0	COG1082@1|root,COG1082@2|Bacteria,2H1AC@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD2_k127_96207_1	1499680.CCFE01000016_gene1017	6.243e-62	218.0	COG3467@1|root,COG3467@2|Bacteria,1V62M@1239|Firmicutes,4HH3G@91061|Bacilli,1ZRFB@1386|Bacillus	91061|Bacilli	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
HKD2_k127_96207_0	1403313.AXBR01000023_gene2493	4.667e-239	745.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus	91061|Bacilli	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD2_k127_9686354_3	1285586.H131_10183	1.73e-23	102.0	2EAGM@1|root,32WM7@2|Bacteria,1VC0B@1239|Firmicutes,4HKZR@91061|Bacilli,3IYKG@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9686354_4	1196031.ALEG01000041_gene2657	6.658e-06	50.0	29TDU@1|root,30EM0@2|Bacteria,1UCPY@1239|Firmicutes,4IP66@91061|Bacilli,1ZPFU@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9686354_2	1123009.AUID01000022_gene1364	2.525e-45	169.0	2EE6D@1|root,3380Z@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_4
HKD2_k127_9686354_1	109871.XP_006683197.1	5.705e-70	240.0	COG2896@1|root,KOG2876@2759|Eukaryota,38F0A@33154|Opisthokonta,3NV9S@4751|Fungi	4751|Fungi	H	Molybdenum cofactor biosynthesis protein	-	-	4.1.99.22,4.6.1.17	ko:K03637,ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,MoaC,Mob_synth_C,Radical_SAM
HKD2_k127_9686354_0	946235.CAER01000004_gene126	9.918e-81	274.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,4HEA2@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
HKD2_k127_9692212_2	1403313.AXBR01000021_gene3212	5.07e-148	474.0	COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus	91061|Bacilli	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iSB619.SA_RS05465	UbiA
HKD2_k127_9692212_1	1403313.AXBR01000021_gene3211	3.928e-181	572.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus	91061|Bacilli	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
HKD2_k127_9692212_0	1403313.AXBR01000021_gene3210	0.0	1104.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus	91061|Bacilli	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HKD2_k127_9692212_5	1403313.AXBR01000021_gene3209	8.906e-117	377.0	COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HAHK@91061|Bacilli,1ZBVD@1386|Bacillus	91061|Bacilli	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD2_k127_9692212_10	1403313.AXBR01000021_gene3208	3.228e-38	145.0	COG3125@1|root,COG3125@2|Bacteria,1V855@1239|Firmicutes,4HJV7@91061|Bacilli,1ZH0W@1386|Bacillus	91061|Bacilli	C	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4	ctaF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	iYO844.BSU14920	COX4_pro
HKD2_k127_9692212_3	1403313.AXBR01000021_gene3207	1.78e-141	454.0	COG3336@1|root,COG3336@2|Bacteria,1TQFK@1239|Firmicutes,4H9WN@91061|Bacilli,1ZBC8@1386|Bacillus	91061|Bacilli	S	cytochrome c oxidase	ctaG	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
HKD2_k127_9692212_6	666686.B1NLA3E_05905	3.099e-76	258.0	COG2322@1|root,COG2322@2|Bacteria,1V3WX@1239|Firmicutes,4HHCU@91061|Bacilli,1ZQR4@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
HKD2_k127_9692212_7	1403313.AXBR01000021_gene3205	7.733e-58	202.0	2AHI2@1|root,317VK@2|Bacteria,1V6HY@1239|Firmicutes,4HJHD@91061|Bacilli,1ZHCP@1386|Bacillus	91061|Bacilli	S	YugN-like family	ylbA	-	-	-	-	-	-	-	-	-	-	-	YugN
HKD2_k127_9692212_4	1403313.AXBR01000021_gene3204	1.3e-136	443.0	COG2340@1|root,COG2340@2|Bacteria,1UYZ4@1239|Firmicutes,4HBTC@91061|Bacilli,1ZCGK@1386|Bacillus	91061|Bacilli	S	protein with SCP PR1 domains	ylbC	-	-	-	-	-	-	-	-	-	-	-	CAP,CAP_assoc_N
HKD2_k127_9692212_9	1403313.AXBR01000021_gene3200	2.97e-42	159.0	2DV4S@1|root,32UYM@2|Bacteria,1VA7R@1239|Firmicutes,4HMUX@91061|Bacilli,1ZI1G@1386|Bacillus	91061|Bacilli	S	Putative coat protein	ylbD	-	-	-	-	-	-	-	-	-	-	-	YlbD_coat
HKD2_k127_9692212_11	1403313.AXBR01000021_gene3199	8.362e-32	125.0	2ED1C@1|root,336YB@2|Bacteria,1VJ46@1239|Firmicutes,4HPWX@91061|Bacilli,1ZJ6S@1386|Bacillus	91061|Bacilli	S	YlbE-like protein	ylbE	-	-	-	-	-	-	-	-	-	-	-	YlbE
HKD2_k127_9692212_12	1403313.AXBR01000021_gene3198	2.131e-27	116.0	2EC1D@1|root,3360J@2|Bacteria,1VFXA@1239|Firmicutes,4HNYC@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9692212_8	1174504.AJTN02000218_gene3133	1.74e-57	203.0	COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli,1ZG76@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0342 family	ylbF	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HKD2_k127_9692212_13	1403313.AXBR01000021_gene3194	9.76e-17	79.0	COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,1ZI4I@1386|Bacillus	91061|Bacilli	S	UPF0298 protein	ylbG	-	-	-	-	-	-	-	-	-	-	-	DUF2129
HKD2_k127_96935_4	1273538.G159_16580	3.482e-16	78.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,26E35@186818|Planococcaceae	91061|Bacilli	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD2_k127_96935_0	1461580.CCAS010000104_gene4525	1.353e-146	469.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,4HB57@91061|Bacilli,1ZCN9@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	yetK	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD2_k127_96935_2	1347086.CCBA010000030_gene318	8.503e-109	364.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	yjlD	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iYO844.BSU12290	Pyr_redox_2
HKD2_k127_96935_3	665959.HMPREF1013_01634	2.364e-16	81.0	COG3729@1|root,COG3729@2|Bacteria,1V71P@1239|Firmicutes,4HJ8A@91061|Bacilli,1ZGZA@1386|Bacillus	91061|Bacilli	S	general stress protein	gsiB	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG,LEA_5
HKD2_k127_96935_1	218284.CCDN010000007_gene3866	1.631e-134	430.0	COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus	91061|Bacilli	IQ	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD2_k127_9706969_24	665952.HMPREF1015_03148	4.156e-05	46.0	COG4972@1|root,COG4972@2|Bacteria,1TSTG@1239|Firmicutes,4HFQU@91061|Bacilli,1ZC5N@1386|Bacillus	91061|Bacilli	NU	COG4972 Tfp pilus assembly protein, ATPase PilM	-	-	-	ko:K02662,ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
HKD2_k127_9706969_21	1033734.CAET01000069_gene2461	3.258e-29	124.0	COG3166@1|root,COG3166@2|Bacteria,1VBC6@1239|Firmicutes,4HMG7@91061|Bacilli,1ZI0A@1386|Bacillus	91061|Bacilli	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
HKD2_k127_9706969_22	1131730.BAVI_03159	5.006e-28	126.0	2BA87@1|root,323NA@2|Bacteria,1V54Z@1239|Firmicutes,4HGZH@91061|Bacilli,1ZIG0@1386|Bacillus	91061|Bacilli	-	-	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,PilO
HKD2_k127_9706969_26	1297581.H919_01455	0.0003753	52.0	COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,21VRT@150247|Anoxybacillus	91061|Bacilli	M	Lysin motif	ypbE	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD2_k127_9706969_25	1499680.CCFE01000018_gene1443	0.0002688	44.0	2DTMA@1|root,33KWF@2|Bacteria,1VQ6W@1239|Firmicutes,4HSQC@91061|Bacilli,1ZCP7@1386|Bacillus	91061|Bacilli	-	-	spoIIB	-	-	ko:K06380	-	-	-	-	ko00000	-	-	-	SPOR
HKD2_k127_9706969_20	1403313.AXBR01000009_gene776	1.911e-43	169.0	2DTMA@1|root,33KWF@2|Bacteria,1VQ6W@1239|Firmicutes,4HSQC@91061|Bacilli,1ZCP7@1386|Bacillus	91061|Bacilli	-	-	spoIIB	-	-	ko:K06380	-	-	-	-	ko00000	-	-	-	SPOR
HKD2_k127_9706969_12	1403313.AXBR01000009_gene775	3.305e-77	263.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,1ZGDP@1386|Bacillus	91061|Bacilli	D	septum formation protein Maf	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HKD2_k127_9706969_8	1403313.AXBR01000009_gene774	6.463e-127	407.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,1ZBYH@1386|Bacillus	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD2_k127_9706969_1	1403313.AXBR01000009_gene773	2.46e-197	617.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZB43@1386|Bacillus	91061|Bacilli	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD2_k127_9706969_9	1403313.AXBR01000009_gene772	5.228e-124	402.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,1ZC8X@1386|Bacillus	91061|Bacilli	M	Involved in formation and maintenance of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HKD2_k127_9706969_19	1403313.AXBR01000009_gene771	1.257e-48	179.0	COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNWW@91061|Bacilli,1ZGID@1386|Bacillus	91061|Bacilli	M	shape-determining protein	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
HKD2_k127_9706969_10	1403313.AXBR01000009_gene770	2.403e-111	363.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,1ZDSJ@1386|Bacillus	91061|Bacilli	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
HKD2_k127_9706969_3	1403313.AXBR01000009_gene769	7.875e-157	496.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,1ZB5P@1386|Bacillus	91061|Bacilli	D	Belongs to the ParA family	minD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
HKD2_k127_9706969_17	441769.ABFU01000048_gene3724	1.087e-49	186.0	COG0739@1|root,COG0739@2|Bacteria,1TSQI@1239|Firmicutes,4HFC8@91061|Bacilli,1ZFJN@1386|Bacillus	91061|Bacilli	M	COG0739 Membrane proteins related to metalloendopeptidases	spoIVFA	-	-	ko:K06401	-	-	-	-	ko00000	-	-	-	Peptidase_M23
HKD2_k127_9706969_5	1403313.AXBR01000009_gene766	6.253e-141	451.0	COG1994@1|root,COG1994@2|Bacteria,1V3FY@1239|Firmicutes,4HF7E@91061|Bacilli,1ZRS3@1386|Bacillus	91061|Bacilli	S	COG1994 Zn-dependent proteases	spoIVFB	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
HKD2_k127_9706969_7	1117379.BABA_18177	7.821e-131	435.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus	91061|Bacilli	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
HKD2_k127_9706969_16	1403313.AXBR01000009_gene764	1.599e-52	186.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,1ZGZG@1386|Bacillus	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HKD2_k127_9706969_18	1403313.AXBR01000009_gene763	1.411e-49	178.0	COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,1ZI1F@1386|Bacillus	91061|Bacilli	J	ribosomal protein	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
HKD2_k127_9706969_15	1403313.AXBR01000009_gene762	1.236e-54	192.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,1ZGZ9@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD2_k127_9706969_23	1385514.N782_03495	1.186e-07	53.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9706969_14	1403313.AXBR01000009_gene761	1.488e-71	245.0	COG3290@1|root,COG3290@2|Bacteria,1V8IS@1239|Firmicutes,4HQ4T@91061|Bacilli,1ZHUN@1386|Bacillus	91061|Bacilli	T	Sporulation initiation phospho-transferase B, C-terminal	spo0B	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K06375	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	SPOB_a,SPOB_ab
HKD2_k127_9706969_0	1403313.AXBR01000009_gene760	5.658e-253	783.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,1ZCM4@1386|Bacillus	91061|Bacilli	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HKD2_k127_9706969_11	1403313.AXBR01000009_gene759	5.377e-79	266.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,4HFRC@91061|Bacilli,1ZFNK@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27910	ACT,ACT_4
HKD2_k127_9706969_6	1403313.AXBR01000009_gene758	9.669e-139	446.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus	91061|Bacilli	E	Prephenate dehydratase	pheA	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27900	ACT,PDT
HKD2_k127_9706969_13	1403313.AXBR01000009_gene756	6.919e-72	246.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,1ZGFK@1386|Bacillus	91061|Bacilli	S	small molecule binding protein (contains 3H domain)	yrxA	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
HKD2_k127_9706969_4	1403313.AXBR01000009_gene755	1.059e-149	482.0	COG1104@1|root,COG1104@2|Bacteria,1TPYU@1239|Firmicutes,4HA5J@91061|Bacilli,1ZCRY@1386|Bacillus	91061|Bacilli	E	Cysteine desulfurase	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD2_k127_9706969_2	1403313.AXBR01000009_gene754	3.033e-181	577.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus	91061|Bacilli	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD2_k127_9712940_0	1403313.AXBR01000023_gene2470	1.168e-187	593.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus	91061|Bacilli	S	ABC1 family	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
HKD2_k127_9712940_6	315750.BPUM_0170	4.504e-40	158.0	COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HEAP@91061|Bacilli,1ZCZZ@1386|Bacillus	91061|Bacilli	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_5
HKD2_k127_9712940_3	315750.BPUM_0169	1.312e-100	336.0	COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,1ZBR2@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	yxlF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD2_k127_9712940_10	406124.ACPC01000008_gene1616	1.827e-10	63.0	2DPPC@1|root,332VC@2|Bacteria,1VM0N@1239|Firmicutes,4HNHT@91061|Bacilli,1ZIVE@1386|Bacillus	91061|Bacilli	S	Phospholipase_D-nuclease N-terminal	yxlE	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
HKD2_k127_9712940_5	1034347.CAHJ01000021_gene3362	3.72e-50	179.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKFQ@91061|Bacilli,1ZH9U@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD2_k127_9712940_8	218284.CCDN010000004_gene3132	2.489e-18	86.0	2EK2J@1|root,33DT0@2|Bacteria,1VMKI@1239|Firmicutes,4HS9U@91061|Bacilli,1ZJJ0@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9712940_9	1131730.BAVI_25629	1.549e-10	66.0	29S0H@1|root,30D4U@2|Bacteria,1UAUP@1239|Firmicutes,4IM7H@91061|Bacilli,1ZJEE@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF5345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5345
HKD2_k127_9712940_4	935836.JAEL01000101_gene4446	1.029e-62	220.0	COG1595@1|root,COG1595@2|Bacteria,1VB37@1239|Firmicutes,4HMZ2@91061|Bacilli,1ZCWY@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigY	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD2_k127_9712940_11	1340434.AXVA01000016_gene701	1.506e-05	47.0	2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus	91061|Bacilli	-	-	yozC	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9712940_2	1174504.AJTN02000001_gene2851	2.721e-122	398.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus	91061|Bacilli	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	yeaB	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD2_k127_9712940_1	1403313.AXBR01000023_gene2488	1.112e-127	417.0	COG4191@1|root,COG4191@2|Bacteria,1TRYP@1239|Firmicutes,4HE85@91061|Bacilli,1ZBXM@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisK_N
HKD2_k127_9712940_7	1174504.AJTN02000001_gene2853	5.938e-38	144.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus	91061|Bacilli	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD2_k127_97545_2	1403313.AXBR01000023_gene2343	2.177e-187	589.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU11190	Semialdhyde_dh,Semialdhyde_dhC
HKD2_k127_97545_1	1403313.AXBR01000023_gene2342	2.368e-193	612.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HKD2_k127_97545_6	1403313.AXBR01000023_gene2341	7.756e-123	397.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,1ZF3H@1386|Bacillus	91061|Bacilli	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD2_k127_97545_3	1403313.AXBR01000023_gene2340	1.237e-174	555.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,1ZC2Y@1386|Bacillus	91061|Bacilli	E	acetylornithine aminotransferase	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD2_k127_97545_5	935837.JAEK01000025_gene1595	9.017e-132	430.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4HAYC@91061|Bacilli,1ZBBD@1386|Bacillus	91061|Bacilli	F	Carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HKD2_k127_97545_0	1403313.AXBR01000023_gene2338	0.0	1765.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus	91061|Bacilli	EF	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD2_k127_97545_4	1403313.AXBR01000023_gene2337	6.75e-166	526.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,1ZC5E@1386|Bacillus	91061|Bacilli	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD2_k127_97545_7	1196029.ALIM01000032_gene1309	6.286e-24	102.0	2EG5I@1|root,339XF@2|Bacteria,1VN1D@1239|Firmicutes,4HRD8@91061|Bacilli,1ZIX6@1386|Bacillus	91061|Bacilli	S	YjzC-like protein	yjzC	-	-	-	-	-	-	-	-	-	-	-	YjzC
HKD2_k127_9768460_4	1403313.AXBR01000021_gene3020	2.676e-90	299.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus	91061|Bacilli	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HKD2_k127_9768460_3	1403313.AXBR01000021_gene3021	7.502e-141	452.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,4HBJD@91061|Bacilli,1ZDBQ@1386|Bacillus	91061|Bacilli	E	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD2_k127_9768460_5	1461580.CCAS010000057_gene3774	1.395e-42	157.0	COG2359@1|root,COG2359@2|Bacteria,1V6G8@1239|Firmicutes,4HIQV@91061|Bacilli,1ZH05@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein S	spoVS	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
HKD2_k127_9768460_2	1174504.AJTN02000258_gene1572	1.544e-155	493.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,1ZC3D@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
HKD2_k127_9768460_6	1385514.N782_03495	1.888e-06	50.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9768460_0	1403313.AXBR01000021_gene3024	7.801e-303	932.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,1ZBGP@1386|Bacillus	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HKD2_k127_9768460_1	1403313.AXBR01000021_gene3025	1.18e-189	595.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,1ZCUX@1386|Bacillus	91061|Bacilli	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HKD2_k127_9805528_6	1444310.JANV01000129_gene1133	4.948e-70	240.0	COG1284@1|root,COG1284@2|Bacteria,1V3MX@1239|Firmicutes,4HHN4@91061|Bacilli,1ZEF3@1386|Bacillus	91061|Bacilli	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
HKD2_k127_9805528_0	1403313.AXBR01000017_gene3659	0.0	1199.0	COG4581@1|root,COG4581@2|Bacteria,1TRYX@1239|Firmicutes,4HU79@91061|Bacilli,1ZE6K@1386|Bacillus	91061|Bacilli	L	COG0513 Superfamily II DNA and RNA helicases	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
HKD2_k127_9805528_2	1461580.CCAS010000007_gene1074	4.414e-248	770.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HDFJ@91061|Bacilli,1ZQG5@1386|Bacillus	91061|Bacilli	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
HKD2_k127_9805528_3	666686.B1NLA3E_07805	9.284e-123	401.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZDF0@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD2_k127_9805528_4	796606.BMMGA3_16550	6.444e-111	372.0	COG3307@1|root,COG3307@2|Bacteria,1V8CF@1239|Firmicutes,4HP2H@91061|Bacilli,1ZGMU@1386|Bacillus	91061|Bacilli	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HKD2_k127_9805528_5	1121091.AUMP01000009_gene4057	9.414e-89	293.0	COG2050@1|root,COG2050@2|Bacteria,1V1XV@1239|Firmicutes,4HFUV@91061|Bacilli	91061|Bacilli	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD2_k127_9805528_1	1403313.AXBR01000010_gene1178	6.314e-303	934.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HKD2_k127_9805528_8	1307436.PBF_11462	1.102e-13	75.0	29S1T@1|root,30D68@2|Bacteria,1UAWT@1239|Firmicutes,4IM9M@91061|Bacilli,1ZJJ7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9805528_7	665959.HMPREF1013_01921	4.855e-19	87.0	2EKRV@1|root,33EFM@2|Bacteria,1VQ20@1239|Firmicutes,4HSEI@91061|Bacilli,1ZK5P@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9805528_9	345219.Bcoa_2731	2.435e-13	72.0	COG3462@1|root,COG3462@2|Bacteria,1VKBD@1239|Firmicutes,4HRBF@91061|Bacilli	91061|Bacilli	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
HKD2_k127_9823864_1	1174504.AJTN02000240_gene4353	6.662e-195	614.0	COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,4IS86@91061|Bacilli,1ZBK2@1386|Bacillus	91061|Bacilli	G	Major Facilitator	yceI	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
HKD2_k127_9823864_0	1403313.AXBR01000022_gene2791	6.022e-296	911.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	dhaS	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD2_k127_9853608_7	1403313.AXBR01000008_gene592	4.158e-99	325.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,1ZCSH@1386|Bacillus	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD2_k127_9853608_10	1243664.CAVL020000006_gene4940	1.371e-60	211.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,1ZG79@1386|Bacillus	91061|Bacilli	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	iYO844.BSU25300	dCMP_cyt_deam_1
HKD2_k127_9853608_13	1461580.CCAS010000005_gene765	1.678e-32	130.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,1ZHW0@1386|Bacillus	91061|Bacilli	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
HKD2_k127_9853608_8	1174504.AJTN02000262_gene675	7.542e-74	251.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,1ZG7I@1386|Bacillus	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
HKD2_k127_9853608_0	796606.BMMGA3_11955	1.17e-247	783.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus	91061|Bacilli	S	membrane-associated HD superfamily hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
HKD2_k127_9853608_3	1403313.AXBR01000008_gene597	1.176e-174	550.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1ZBVE@1386|Bacillus	91061|Bacilli	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HKD2_k127_9853608_2	1403313.AXBR01000008_gene598	1.89e-185	586.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus	91061|Bacilli	S	Stage IV sporulation	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
HKD2_k127_9853608_11	665952.HMPREF1015_00316	3.395e-41	153.0	2E4EZ@1|root,32ZA5@2|Bacteria,1VF5C@1239|Firmicutes,4HNQG@91061|Bacilli,1ZHZA@1386|Bacillus	91061|Bacilli	S	sporulation protein YqfC	yqfC	-	-	-	-	-	-	-	-	-	-	-	YabP
HKD2_k127_9853608_4	1403313.AXBR01000008_gene601	2.378e-171	541.0	COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,1ZD1V@1386|Bacillus	91061|Bacilli	S	UPF0365 protein	yqfA	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
HKD2_k127_9853608_1	1403313.AXBR01000008_gene602	1.945e-192	609.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,1ZCTF@1386|Bacillus	91061|Bacilli	O	COG1030 Membrane-bound serine protease (ClpP class)	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
HKD2_k127_9853608_9	1403313.AXBR01000008_gene603	2.047e-66	229.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,1ZGGX@1386|Bacillus	91061|Bacilli	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HKD2_k127_9853608_14	272626.lin1506	7.816e-24	101.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,26M1X@186820|Listeriaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HKD2_k127_9853608_5	1403313.AXBR01000008_gene605	1.16e-120	394.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus	91061|Bacilli	P	COG1283 Na phosphate symporter	yqeW	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
HKD2_k127_9853608_6	1403313.AXBR01000008_gene606	3.115e-110	359.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD2_k127_9853608_12	1403313.AXBR01000008_gene607	8.005e-38	143.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,1ZB8Q@1386|Bacillus	91061|Bacilli	J	ribosomal protein S12 methylthiotransferase	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD2_k127_9872820_3	1340434.AXVA01000010_gene5484	3.55e-05	46.0	29TE4@1|root,30EM9@2|Bacteria,1UCQ9@1239|Firmicutes,4IP6H@91061|Bacilli,1ZPG8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9872820_2	1449063.JMLS01000012_gene5468	2.552e-58	211.0	2DN86@1|root,32W1X@2|Bacteria,1VA8R@1239|Firmicutes,4HN75@91061|Bacilli,26VAJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9872820_1	485913.Krac_11202	9.949e-115	385.0	COG3670@1|root,COG3670@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
HKD2_k127_9872820_4	1123274.KB899451_gene1559	3.588e-05	48.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
HKD2_k127_9872820_0	1117379.BABA_16042	1.308e-125	406.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4HBP3@91061|Bacilli,1ZFXU@1386|Bacillus	91061|Bacilli	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD2_k127_9885111_0	1403313.AXBR01000002_gene4134	1.224e-267	858.0	COG3115@1|root,COG3115@2|Bacteria,1TR7S@1239|Firmicutes,4HE65@91061|Bacilli,1ZD8K@1386|Bacillus	91061|Bacilli	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9885111_2	986075.CathTA2_2138	1.76e-140	452.0	COG2070@1|root,COG2070@2|Bacteria,1TT5U@1239|Firmicutes,4HCS7@91061|Bacilli	91061|Bacilli	S	2-Nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
HKD2_k127_9885111_3	1403313.AXBR01000024_gene4800	3.914e-16	79.0	2EPEG@1|root,33H12@2|Bacteria,1VK9A@1239|Firmicutes,4HSBT@91061|Bacilli,1ZK9G@1386|Bacillus	91061|Bacilli	S	IDEAL	-	-	-	-	-	-	-	-	-	-	-	-	IDEAL
HKD2_k127_9885111_1	1403313.AXBR01000023_gene2507	1.035e-157	502.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,1ZBEH@1386|Bacillus	91061|Bacilli	C	Inorganic pyrophosphatase	ppaC	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DHH,DHHA2
HKD2_k127_989834_11	697284.ERIC2_c31770	4.492e-77	261.0	COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,26RKC@186822|Paenibacillaceae	91061|Bacilli	E	Proline dehydrogenase	fadM	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD2_k127_989834_0	315749.Bcer98_0289	2.014e-288	890.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZCI4@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family. RocA subfamily	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	iYO844.BSU37780	Aldedh
HKD2_k127_989834_4	1211814.CAPG01000070_gene3284	2.297e-156	497.0	2BZ6P@1|root,2Z8AB@2|Bacteria,1TRT3@1239|Firmicutes,4HD7G@91061|Bacilli,1ZQQP@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF2935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2935
HKD2_k127_989834_13	574375.BAGA_08225	4.726e-63	217.0	2DM7B@1|root,3212W@2|Bacteria,1V80J@1239|Firmicutes,4HK6G@91061|Bacilli,1ZHB0@1386|Bacillus	91061|Bacilli	S	YmaF family	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
HKD2_k127_989834_17	666686.B1NLA3E_21895	4.49e-15	80.0	28P1F@1|root,2ZBXS@2|Bacteria,1V1PR@1239|Firmicutes,4IAIX@91061|Bacilli,1ZIVA@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2680)	yckD	-	-	-	-	-	-	-	-	-	-	-	DUF2680
HKD2_k127_989834_1	1117379.BABA_14907	8.071e-203	639.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ywqF	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD2_k127_989834_12	1131730.BAVI_18542	6.122e-75	255.0	COG0671@1|root,COG0671@2|Bacteria,1V33Y@1239|Firmicutes,4HGAT@91061|Bacilli,1ZFPM@1386|Bacillus	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	pgpB1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD2_k127_989834_3	935836.JAEL01000112_gene1300	1.082e-178	566.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,1ZD6V@1386|Bacillus	91061|Bacilli	M	Glycosyl Transferase	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD2_k127_989834_2	1243664.CAVL020000016_gene1970	7.171e-184	582.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,1ZBEY@1386|Bacillus	91061|Bacilli	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD2_k127_989834_6	1211814.CAPG01000029_gene1414	1.552e-153	488.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,1ZBP3@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_989834_5	1231057.AMGD01000033_gene1728	1.731e-154	493.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,26EBF@186818|Planococcaceae	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD2_k127_989834_9	1121468.AUBR01000023_gene2752	1.893e-85	290.0	COG0411@1|root,COG0411@2|Bacteria	2|Bacteria	E	ABC transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
HKD2_k127_989834_7	1231057.AMGD01000033_gene1730	2.737e-123	398.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,26ECE@186818|Planococcaceae	91061|Bacilli	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
HKD2_k127_989834_8	279010.BL00260	3.684e-122	411.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZMP8@1386|Bacillus	91061|Bacilli	NT	methyl-accepting chemotaxis protein	yoaH	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
HKD2_k127_989834_14	1243664.CAVL020000016_gene1994	7.71e-58	204.0	COG3339@1|root,COG3339@2|Bacteria,1VB9N@1239|Firmicutes,4HM3U@91061|Bacilli,1ZFMI@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HKD2_k127_989834_15	333138.LQ50_13765	3.225e-24	102.0	2E5UW@1|root,330J3@2|Bacteria,1VFMQ@1239|Firmicutes,4HPRZ@91061|Bacilli,1ZIYY@1386|Bacillus	91061|Bacilli	S	Small acid-soluble spore protein H family	sspH	-	-	ko:K06425	-	-	-	-	ko00000	-	-	-	SspH
HKD2_k127_989834_16	1033734.CAET01000038_gene96	3.154e-22	98.0	2E7S8@1|root,3327E@2|Bacteria,1VGU6@1239|Firmicutes,4HQVC@91061|Bacilli,1ZJ5I@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_989834_10	1384049.CD29_13720	2.542e-81	273.0	COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,3IWIK@400634|Lysinibacillus	91061|Bacilli	C	Quinone oxidoreductase	yhfP	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD2_k127_9951602_4	1403313.AXBR01000028_gene5100	1.123e-174	550.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HKD2_k127_9951602_15	1243664.CAVL020000060_gene3227	2.796e-30	121.0	COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,1ZIXZ@1386|Bacillus	91061|Bacilli	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
HKD2_k127_9951602_3	1403313.AXBR01000028_gene5098	1.847e-212	666.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,1ZAVV@1386|Bacillus	91061|Bacilli	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
HKD2_k127_9951602_2	1403313.AXBR01000028_gene5097	5.351e-260	805.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD2_k127_9951602_16	1243664.CAVL020000060_gene3224	1.446e-17	83.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,1ZJ74@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD2_k127_9951602_14	1403313.AXBR01000028_gene5095	4.24e-54	191.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,1ZHUH@1386|Bacillus	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD2_k127_9951602_8	1403313.AXBR01000028_gene5094	1.378e-126	410.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,1ZBYD@1386|Bacillus	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HKD2_k127_9951602_11	1403313.AXBR01000028_gene5093	6.317e-94	312.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,1ZDGU@1386|Bacillus	91061|Bacilli	S	single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
HKD2_k127_9951602_1	1403313.AXBR01000028_gene5092	7.428e-265	820.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HKD2_k127_9951602_0	1034347.CAHJ01000089_gene1656	0.0	1106.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,1ZB67@1386|Bacillus	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD2_k127_9951602_17	1385514.N782_03495	7.625e-07	51.0	2EHHZ@1|root,33B9Y@2|Bacteria,1VQKM@1239|Firmicutes,4HS6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9951602_7	1403313.AXBR01000028_gene5090	1.196e-126	408.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,1ZAWG@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HKD2_k127_9951602_6	1174504.AJTN02000193_gene4163	1.612e-143	462.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,1ZCDV@1386|Bacillus	91061|Bacilli	D	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD2_k127_9951602_5	1403313.AXBR01000028_gene5088	8.581e-145	461.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus	91061|Bacilli	D	COG1192 ATPases involved in chromosome partitioning	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD2_k127_9951602_9	218284.CCDN010000007_gene3801	4.671e-111	365.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,1ZBDT@1386|Bacillus	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
HKD2_k127_9951602_10	1403313.AXBR01000028_gene5086	2.772e-95	318.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,1ZBSK@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF554)	ydfK	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
HKD2_k127_9951602_12	1403313.AXBR01000028_gene5085	2.935e-88	296.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,4HH5B@91061|Bacilli,1ZCER@1386|Bacillus	91061|Bacilli	S	Sporulation protein YyaC	yyaC	-	-	-	-	-	-	-	-	-	-	-	DUF1256
HKD2_k127_9951602_13	1403313.AXBR01000028_gene5084	2.035e-86	292.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus	91061|Bacilli	M	Mechanosensitive ion channel	ykuT	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HKD2_k127_9961282_5	935837.JAEK01000005_gene4411	4.349e-60	209.0	COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZB5B@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	ymfD	-	-	ko:K08221	-	-	-	-	ko00000,ko02000	2.A.1.32	-	-	MFS_1,MFS_2,Sugar_tr
HKD2_k127_9961282_6	935837.JAEK01000055_gene1509	1.114e-45	169.0	2DJCZ@1|root,305NR@2|Bacteria,1TYFY@1239|Firmicutes,4I7K5@91061|Bacilli,1ZIK3@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD2_k127_9961282_4	665952.HMPREF1015_02231	2.437e-86	289.0	COG0670@1|root,COG0670@2|Bacteria,1V6RG@1239|Firmicutes,4HISH@91061|Bacilli,1ZCV6@1386|Bacillus	91061|Bacilli	S	Belongs to the BI1 family	yetJ	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
HKD2_k127_9961282_2	1403313.AXBR01000005_gene1797	1.77e-183	580.0	COG0438@1|root,COG0438@2|Bacteria,1UZT6@1239|Firmicutes,4HFIA@91061|Bacilli,1ZEN6@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD2_k127_9961282_1	1403313.AXBR01000005_gene1796	1.325e-211	661.0	COG0515@1|root,COG0515@2|Bacteria,1VBSJ@1239|Firmicutes,4HKRP@91061|Bacilli,1ZHE2@1386|Bacillus	91061|Bacilli	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	RIO1
HKD2_k127_9961282_3	1403313.AXBR01000005_gene1795	2.296e-177	559.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4HAN7@91061|Bacilli,1ZQ48@1386|Bacillus	91061|Bacilli	M	NAD-dependent epimerase dehydratase	capI	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD2_k127_9961282_0	1121121.KB894292_gene1101	5.077e-292	900.0	COG0579@1|root,COG0579@2|Bacteria,1TNZY@1239|Firmicutes,4H9PS@91061|Bacilli,26QFX@186822|Paenibacillaceae	91061|Bacilli	S	malate quinone oxidoreductase	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS12375	Mqo
HKD2_k127_9984815_1	1450694.BTS2_2076	2.294e-102	346.0	COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HCW1@91061|Bacilli,1ZDKH@1386|Bacillus	91061|Bacilli	S	drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD2_k127_9984815_0	35841.BT1A1_1898	5.022e-119	388.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZEXI@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD2_k127_9984815_2	234267.Acid_0425	9.036e-41	173.0	COG1501@1|root,COG1501@2|Bacteria,3Y717@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	-
## 3740 queries scanned
## Total time (seconds): 64.51667881011963
## Rate: 57.97 q/s