## Fri Nov 15 17:07:59 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin9/HKD_3_bin.10.fa -m mmseqs --itype genome -o HKD_3_bin.10 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HKD_3_bin.10 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD3_k127_1000657_5	945713.IALB_1021	3.522e-17	83.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,SLH,WG_beta_rep
HKD3_k127_1000657_2	925409.KI911562_gene2981	4.526e-97	332.0	28KFX@1|root,2ZA1W@2|Bacteria,4P3W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1000657_3	1267211.KI669560_gene1847	1.458e-45	168.0	COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,1ISU6@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD3_k127_1000657_4	925409.KI911562_gene2307	1.531e-34	140.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1IT0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1000657_0	1123248.KB893370_gene5064	1.022e-273	848.0	COG1884@1|root,COG1884@2|Bacteria,4PN0H@976|Bacteroidetes,1IPCT@117747|Sphingobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HKD3_k127_1000657_1	468059.AUHA01000005_gene2521	1.35e-179	574.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	ampH	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Beta-lactamase2,DUF3471
HKD3_k127_1005532_7	1048983.EL17_10995	3.63e-32	132.0	COG1651@1|root,COG1651@2|Bacteria,4NH0U@976|Bacteroidetes,47M6I@768503|Cytophagia	976|Bacteroidetes	O	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Thioredoxin_4,VKOR
HKD3_k127_1005532_6	391596.PBAL39_19424	4.506e-44	175.0	COG0526@1|root,COG0526@2|Bacteria,4NNY5@976|Bacteroidetes,1IT32@117747|Sphingobacteriia	976|Bacteroidetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
HKD3_k127_1005532_1	761193.Runsl_1985	3.879e-250	792.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47JYM@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
HKD3_k127_1005532_4	1123277.KB893198_gene6327	5.508e-72	259.0	COG0845@1|root,COG0845@2|Bacteria,4P48K@976|Bacteroidetes,47PIQ@768503|Cytophagia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HKD3_k127_1005532_8	391596.PBAL39_19424	1.667e-19	99.0	COG0526@1|root,COG0526@2|Bacteria,4NNY5@976|Bacteroidetes,1IT32@117747|Sphingobacteriia	976|Bacteroidetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
HKD3_k127_1005532_11	504472.Slin_0782	8.339e-06	52.0	COG0845@1|root,COG0845@2|Bacteria,4P48K@976|Bacteroidetes,47PIQ@768503|Cytophagia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HKD3_k127_1005532_12	1123277.KB893198_gene6327	1.094e-05	49.0	COG0845@1|root,COG0845@2|Bacteria,4P48K@976|Bacteroidetes,47PIQ@768503|Cytophagia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HKD3_k127_1005532_3	693661.Arcve_1821	2.918e-73	253.0	COG1794@1|root,arCOG02005@2157|Archaea,2XWZW@28890|Euryarchaeota,246CZ@183980|Archaeoglobi	183980|Archaeoglobi	M	aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
HKD3_k127_1005532_2	1267211.KI669560_gene249	6.376e-175	553.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1IP3N@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
HKD3_k127_1005532_5	925409.KI911562_gene523	1.026e-45	177.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes	976|Bacteroidetes	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_1005532_10	929562.Emtol_1034	2.884e-10	63.0	2EA5C@1|root,33MRN@2|Bacteria,4NZEN@976|Bacteroidetes,47X6M@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1005532_0	929562.Emtol_1035	6e-254	786.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,47KD2@768503|Cytophagia	976|Bacteroidetes	CE	Isocitrate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_1019823_2	1123248.KB893318_gene4179	3.506e-119	388.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD3_k127_1019823_5	700598.Niako_4524	1.605e-78	270.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,1IRZV@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM periplasmic binding protein	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
HKD3_k127_1019823_0	925409.KI911562_gene2143	0.0	1265.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1IQ9E@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
HKD3_k127_1019823_4	700598.Niako_0886	1.817e-94	317.0	2BH0I@1|root,32B0P@2|Bacteria,4P6EF@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835,DUF3658
HKD3_k127_1019823_3	925409.KI911562_gene2266	1.722e-97	326.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5I@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
HKD3_k127_1019823_1	925409.KI911562_gene2140	0.0	1045.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1IQV0@117747|Sphingobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_1067627_0	925409.KI911562_gene839	2.815e-166	530.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1IR44@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HKD3_k127_1067627_2	1123248.KB893317_gene4374	2.76e-80	270.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1ISKP@117747|Sphingobacteriia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
HKD3_k127_1067627_1	700598.Niako_6016	1.617e-117	393.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1IQZP@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
HKD3_k127_1067627_3	1121957.ATVL01000005_gene601	2.286e-06	60.0	COG4886@1|root,COG4886@2|Bacteria,4PNPJ@976|Bacteroidetes,47WC6@768503|Cytophagia	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
HKD3_k127_1074790_4	1123248.KB893348_gene214	1.655e-35	136.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HKD3_k127_1074790_1	1123248.KB893348_gene214	4.249e-138	443.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HKD3_k127_1074790_2	1123248.KB893348_gene215	5.523e-72	247.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_1074790_5	1313301.AUGC01000014_gene2471	7.514e-10	67.0	COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_1074790_3	1123248.KB893348_gene261	1.229e-57	206.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes,1J0EF@117747|Sphingobacteriia	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD3_k127_1074790_0	1267211.KI669560_gene775	3.017e-231	721.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	Fer4_8,LUD_dom
HKD3_k127_1102858_4	445961.IW15_21335	0.0005623	44.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I2FF@117743|Flavobacteriia,3ZQ3I@59732|Chryseobacterium	976|Bacteroidetes	S	ACP phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
HKD3_k127_1102858_3	760192.Halhy_6027	3.939e-17	90.0	2CF5H@1|root,32S19@2|Bacteria,4NSPW@976|Bacteroidetes,1IU9V@117747|Sphingobacteriia	976|Bacteroidetes	S	Four helix bundle sensory module for signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1
HKD3_k127_1102858_1	760192.Halhy_0595	4.426e-35	143.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	5.3.1.16	ko:K01814,ko:K03825	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HKD3_k127_1102858_0	1121286.AUMT01000003_gene2234	9.224e-189	598.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,1HWJT@117743|Flavobacteriia,3ZNTM@59732|Chryseobacterium	976|Bacteroidetes	C	4-hydroxybutyrate CoA-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD3_k127_1102858_2	925409.KI911562_gene502	1.255e-26	112.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1IT6C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_1164832_1	700598.Niako_5590	3.127e-98	326.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD3_k127_1164832_0	925409.KI911562_gene1181	1.329e-295	924.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HKD3_k127_1169870_7	700598.Niako_7066	8.202e-85	282.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1IS1Q@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HKD3_k127_1169870_0	925409.KI911562_gene211	3.649e-246	762.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR4T@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
HKD3_k127_1169870_6	1267211.KI669560_gene953	4.066e-85	284.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1ISEW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HKD3_k127_1169870_4	925409.KI911562_gene213	4.759e-104	340.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HKD3_k127_1169870_10	1123248.KB893381_gene1013	7.809e-55	194.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1ISVI@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HKD3_k127_1169870_3	1123248.KB893381_gene1014	7.82e-127	427.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IPR2@117747|Sphingobacteriia	976|Bacteroidetes	NU	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HKD3_k127_1169870_5	700598.Niako_7059	2.543e-95	321.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes	976|Bacteroidetes	P	Phosphate ABC transporter substrate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD3_k127_1169870_9	925409.KI911562_gene218	1.846e-57	206.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1IYAU@117747|Sphingobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD3_k127_1169870_1	925409.KI911562_gene219	3.297e-226	707.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1IW4I@117747|Sphingobacteriia	976|Bacteroidetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HKD3_k127_1169870_8	700598.Niako_1982	6.547e-62	225.0	COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,1IXG8@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_1169870_2	700598.Niako_7050	9.13e-178	565.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IVK0@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the thiolase family	-	-	2.3.1.174,2.3.1.9	ko:K00626,ko:K07823	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_1169870_11	760192.Halhy_5596	2.828e-08	60.0	COG1044@1|root,COG1044@2|Bacteria,4NP38@976|Bacteroidetes,1IXVZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1171990_2	929703.KE386491_gene638	1.019e-51	190.0	COG3637@1|root,COG3637@2|Bacteria,4PM31@976|Bacteroidetes,47KS5@768503|Cytophagia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_1171990_0	925409.KI911562_gene1720	5.458e-272	855.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1IV3Y@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_1171990_1	1123248.KB893332_gene2252	1.078e-78	270.0	29C3H@1|root,32VP8@2|Bacteria,4NXVV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1171990_3	925409.KI911562_gene1206	2.04e-34	133.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1IP2F@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
HKD3_k127_1181909_2	1123248.KB893321_gene543	3.545e-38	153.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
HKD3_k127_1181909_3	925409.KI911562_gene1276	4.978e-06	53.0	2C1KT@1|root,33DVE@2|Bacteria,4NY76@976|Bacteroidetes,1IUF1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1181909_0	1123248.KB893386_gene1863	2.131e-177	564.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1INWU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_1181909_1	925409.KI911562_gene1675	2.33e-44	171.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,1ITFE@117747|Sphingobacteriia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD3_k127_1192489_1	1267211.KI669560_gene1362	1.098e-36	141.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1IS44@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_1192489_0	1267211.KI669560_gene1361	1.72e-227	714.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1IQ8J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_1192489_2	1123248.KB893318_gene4181	4.629e-06	49.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1IPSH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1194232_3	700598.Niako_3669	1.638e-87	299.0	COG1502@1|root,COG1502@2|Bacteria,4P0CZ@976|Bacteroidetes,1J0D9@117747|Sphingobacteriia	976|Bacteroidetes	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HKD3_k127_1194232_0	1123248.KB893316_gene4610	1.17e-161	515.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1IYQQ@117747|Sphingobacteriia	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD3_k127_1194232_2	700598.Niako_6719	3.994e-89	302.0	COG3023@1|root,COG3023@2|Bacteria,4NE38@976|Bacteroidetes,1INQE@117747|Sphingobacteriia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	amiD	-	3.5.1.28	ko:K01447,ko:K11066	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1
HKD3_k127_1194232_6	1120965.AUBV01000007_gene2552	7.406e-23	101.0	COG0477@1|root,COG2814@2|Bacteria,4NUYS@976|Bacteroidetes,47S3H@768503|Cytophagia	976|Bacteroidetes	EGP	Domain of unknown function (DUF3817)	ydzA	-	-	-	-	-	-	-	-	-	-	-	DUF3817
HKD3_k127_1194232_1	929556.Solca_1229	4.984e-93	317.0	COG3187@1|root,COG3187@2|Bacteria,4NEY0@976|Bacteroidetes,1IQ5Y@117747|Sphingobacteriia	976|Bacteroidetes	O	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3,META
HKD3_k127_1194232_7	755732.Fluta_1196	3.64e-15	82.0	COG2030@1|root,COG2030@2|Bacteria,4NUTF@976|Bacteroidetes,1IB9P@117743|Flavobacteriia,2PBY4@246874|Cryomorphaceae	976|Bacteroidetes	I	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
HKD3_k127_1194232_4	1267211.KI669560_gene364	5.688e-72	248.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
HKD3_k127_1194232_5	1267211.KI669560_gene363	3.237e-54	194.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISB0@117747|Sphingobacteriia	976|Bacteroidetes	O	methionine sulfoxide reductase	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HKD3_k127_1196691_1	485918.Cpin_6525	1.134e-63	225.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1IR1A@117747|Sphingobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
HKD3_k127_1196691_3	700598.Niako_7017	1.563e-44	171.0	COG0664@1|root,COG0664@2|Bacteria,4NQ1A@976|Bacteroidetes,1IY7M@117747|Sphingobacteriia	976|Bacteroidetes	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_1196691_0	700598.Niako_4690	0.0	1292.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_1196691_4	1267211.KI669560_gene1564	1.313e-37	149.0	2FEUI@1|root,346TG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1196691_5	925409.KI911562_gene2171	1.539e-26	113.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1ITWJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HKD3_k127_1196691_2	925409.KI911562_gene2126	5.636e-51	187.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1ISE3@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HKD3_k127_1204035_3	485918.Cpin_1483	1.967e-109	360.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,1IPR6@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
HKD3_k127_1204035_0	1121904.ARBP01000025_gene6108	5.172e-258	812.0	COG1874@1|root,COG1874@2|Bacteria,4NINF@976|Bacteroidetes,47NCF@768503|Cytophagia	976|Bacteroidetes	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
HKD3_k127_1204035_2	1121904.ARBP01000025_gene6091	5.844e-145	462.0	COG1830@1|root,COG1830@2|Bacteria,4P0GF@976|Bacteroidetes	976|Bacteroidetes	G	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD3_k127_1204035_1	509635.N824_13790	1.753e-167	533.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_1204035_4	1121904.ARBP01000025_gene6089	3.258e-66	230.0	COG3822@1|root,COG3822@2|Bacteria,4NQZC@976|Bacteroidetes	976|Bacteroidetes	S	Pfam:DUF1498	-	-	-	-	-	-	-	-	-	-	-	-	Lyx_isomer
HKD3_k127_1207155_0	1338011.BD94_0963	2.945e-67	244.0	COG1680@1|root,COG1680@2|Bacteria,4P3CM@976|Bacteroidetes,1I9B4@117743|Flavobacteriia,34RX4@308865|Elizabethkingia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_1207155_1	1336803.PHEL49_2113	6.287e-51	198.0	COG2273@1|root,COG3209@1|root,COG3637@1|root,COG4625@1|root,COG2273@2|Bacteria,COG3209@2|Bacteria,COG3637@2|Bacteria,COG4625@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,SprB
HKD3_k127_1212666_0	700598.Niako_0407	6.73e-220	704.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1IPTV@117747|Sphingobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD3_k127_1212666_1	1267211.KI669560_gene2302	8.822e-151	483.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_128718_0	925409.KI911562_gene2428	3.941e-199	629.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1IV68@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
HKD3_k127_1287706_0	925409.KI911562_gene2304	1.241e-157	505.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_1287706_2	925409.KI911562_gene2395	6.151e-31	130.0	2C0BR@1|root,32Z3H@2|Bacteria,4NVDW@976|Bacteroidetes,1IU2Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
HKD3_k127_1287706_1	1296416.JACB01000029_gene4205	2.861e-70	248.0	COG3497@1|root,COG3497@2|Bacteria,4NEKK@976|Bacteroidetes,1HZQA@117743|Flavobacteriia,2YITF@290174|Aquimarina	976|Bacteroidetes	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
HKD3_k127_1303797_0	468059.AUHA01000002_gene918	4.098e-86	292.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1IY5W@117747|Sphingobacteriia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
HKD3_k127_1303797_1	314285.KT71_06257	7.206e-33	139.0	28KF8@1|root,2ZA1G@2|Bacteria,1NZ2T@1224|Proteobacteria,1SQI9@1236|Gammaproteobacteria,1JAT9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1309709_4	1122605.KB893626_gene2450	4.429e-24	102.0	COG0584@1|root,COG2273@1|root,COG0584@2|Bacteria,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1J1A1@117747|Sphingobacteriia	976|Bacteroidetes	CG	Beta-glucan synthesis-associated protein (SKN1)	-	-	-	-	-	-	-	-	-	-	-	-	GDPD,Glyco_hydro_16
HKD3_k127_1309709_0	991.IW20_15095	1.568e-316	984.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NSID@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_1309709_1	700598.Niako_5234	6.774e-145	473.0	COG4299@1|root,COG4299@2|Bacteria,4NJZJ@976|Bacteroidetes,1IR3E@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
HKD3_k127_1309709_2	929556.Solca_0693	1.349e-79	274.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1IS3G@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Peptidase_S9
HKD3_k127_1309709_3	1267211.KI669560_gene649	4.688e-51	187.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1IS3Y@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-superfamily hydrolase subfamily IA, variant 3	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD3_k127_1312987_1	1296416.JACB01000031_gene2521	7.098e-123	399.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,1HYNT@117743|Flavobacteriia,2YHEH@290174|Aquimarina	976|Bacteroidetes	KL	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
HKD3_k127_1312987_0	925409.KI911562_gene2130	3.926e-152	491.0	COG0038@1|root,COG0038@2|Bacteria,4NFCF@976|Bacteroidetes,1IUVQ@117747|Sphingobacteriia	976|Bacteroidetes	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
HKD3_k127_1313502_1	1121481.AUAS01000012_gene301	6.489e-78	267.0	COG4932@1|root,COG4932@2|Bacteria,4PM22@976|Bacteroidetes,47XZY@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD3_k127_1313502_2	1122605.KB893646_gene8	2.821e-62	222.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,1ITCU@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_1313502_3	1122605.KB893646_gene10	1.372e-09	65.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
HKD3_k127_1313502_0	760192.Halhy_4638	4.245e-232	731.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IRCX@117747|Sphingobacteriia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
HKD3_k127_131647_2	1166018.FAES_4757	3.27e-41	157.0	COG0438@1|root,COG0438@2|Bacteria,4NHUT@976|Bacteroidetes,47P33@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD3_k127_131647_0	1166018.FAES_4758	1.784e-109	366.0	COG0438@1|root,COG0438@2|Bacteria,4NIQ3@976|Bacteroidetes,47KMV@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_131647_1	1166018.FAES_4761	7.503e-108	352.0	COG0438@1|root,COG0438@2|Bacteria,4NEJ6@976|Bacteroidetes,47JTJ@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glycos_transf_1
HKD3_k127_1319413_3	269798.CHU_0107	4.687e-42	157.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,47JG3@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
HKD3_k127_1319413_2	421531.IX38_14660	4.831e-54	194.0	COG2318@1|root,COG2318@2|Bacteria,4NNRD@976|Bacteroidetes,1I4R2@117743|Flavobacteriia,3ZRAI@59732|Chryseobacterium	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
HKD3_k127_1319413_0	700598.Niako_6538	0.0	1053.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_1319413_1	925409.KI911562_gene2518	4.196e-66	233.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	pacL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.8	ko:K01537,ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.24	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD3_k127_1322285_2	1267211.KI669560_gene1526	6.28e-124	398.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1IQ4F@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD3_k127_1322285_3	1267211.KI669560_gene1527	1.404e-91	308.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1ISIA@117747|Sphingobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
HKD3_k127_1322285_0	1123248.KB893318_gene4209	1.251e-144	471.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_1322285_1	700598.Niako_3032	4.367e-142	457.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1INZZ@117747|Sphingobacteriia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD3_k127_132762_0	700598.Niako_4713	1.378e-272	847.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HKD3_k127_132762_3	929556.Solca_1200	0.0006169	52.0	COG2885@1|root,COG2931@1|root,COG3064@1|root,COG3209@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,COG3064@2|Bacteria,COG3209@2|Bacteria,4PN6B@976|Bacteroidetes,1IRU2@117747|Sphingobacteriia	976|Bacteroidetes	M	Collagen triple helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
HKD3_k127_132762_2	471854.Dfer_5468	9.39e-19	100.0	COG5295@1|root,COG5295@2|Bacteria,4PHWV@976|Bacteroidetes,47T1I@768503|Cytophagia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_132762_1	1123248.KB893381_gene1032	5.798e-81	274.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,1IRDN@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
HKD3_k127_1328126_3	1267211.KI669560_gene324	1.792e-32	128.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	AHH,Flg_new,RHS_repeat
HKD3_k127_1328126_1	525373.HMPREF0766_11272	1.258e-51	195.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1IRXE@117747|Sphingobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1328126_2	1123037.AUDE01000041_gene1243	1.767e-44	172.0	COG0582@1|root,COG0582@2|Bacteria,4NS70@976|Bacteroidetes,1I4DE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD3_k127_1328126_0	925409.KI911562_gene2290	1.359e-140	477.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1IRXE@117747|Sphingobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1328126_4	1122605.KB893647_gene285	1.52e-17	82.0	COG3209@1|root,COG3501@1|root,COG3209@2|Bacteria,COG3501@2|Bacteria,4NE5D@976|Bacteroidetes	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1328162_2	700598.Niako_0405	5.032e-173	554.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD3_k127_1328162_0	1267211.KI669560_gene1396	2.809e-303	951.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IQWN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
HKD3_k127_1328162_3	717785.HYPMC_0530	0.0004742	44.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1328162_1	504472.Slin_5502	7.312e-210	658.0	28KCX@1|root,2Z9ZQ@2|Bacteria,4NJ7S@976|Bacteroidetes,47JNB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1331017_0	1122605.KB893625_gene2097	2.243e-142	457.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IV50@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD3_k127_1331017_1	929556.Solca_4479	3.419e-141	455.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_1335447_2	1250005.PHEL85_0335	2.347e-18	91.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,3VW6J@52959|Polaribacter	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_1335447_3	1239962.C943_03767	3.472e-08	64.0	2FG5W@1|root,3482C@2|Bacteria,4P5PR@976|Bacteroidetes,47VV9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1335447_1	1239962.C943_03687	8.689e-34	136.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,47QGE@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD3_k127_1335447_0	1086011.HJ01_03172	4.271e-64	236.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,1HYFK@117743|Flavobacteriia,2NWFB@237|Flavobacterium	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
HKD3_k127_1339580_3	1123248.KB893348_gene167	1.937e-107	354.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1IQ8E@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
HKD3_k127_1339580_2	925409.KI911562_gene925	1.591e-138	448.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1INUR@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
HKD3_k127_1339580_1	1267211.KI669560_gene663	1.166e-161	515.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HKD3_k127_1339580_7	1305737.JAFX01000001_gene978	5.956e-36	141.0	COG4270@1|root,COG4270@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,DoxX_2
HKD3_k127_1339580_0	1267211.KI669560_gene299	1.416e-169	540.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1IP0R@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_1339580_5	1121904.ARBP01000012_gene1244	5.828e-61	224.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1339580_8	504472.Slin_3973	6.685e-30	128.0	2B4D9@1|root,31X4V@2|Bacteria,4NRUS@976|Bacteroidetes,47QTV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_1339580_6	1121875.KB907547_gene2993	9.723e-60	213.0	COG2095@1|root,COG2095@2|Bacteria	2|Bacteria	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
HKD3_k127_1339580_4	1121875.KB907549_gene1997	1.372e-71	243.0	COG3408@1|root,COG3408@2|Bacteria,4PKJG@976|Bacteroidetes,1IJAW@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
HKD3_k127_1343781_2	1283284.AZUK01000001_gene2453	5.865e-21	110.0	29W90@1|root,30HUD@2|Bacteria,1R92S@1224|Proteobacteria,1S1CJ@1236|Gammaproteobacteria,1Y5WT@135624|Aeromonadales	135624|Aeromonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1343781_1	1121898.Q766_05980	3.243e-74	286.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
HKD3_k127_1343781_0	1313421.JHBV01000031_gene1535	7.031e-173	550.0	COG0281@1|root,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,PTA_PTB,malic
HKD3_k127_1346412_0	700598.Niako_4696	3.251e-121	392.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_1346412_3	1267211.KI669560_gene1307	5.295e-21	101.0	2EHH8@1|root,33B95@2|Bacteria,4NXPK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1346412_1	925409.KI911562_gene10	3.332e-61	218.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1IRYX@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HKD3_k127_1346412_2	700598.Niako_4701	8.78e-39	148.0	COG0824@1|root,COG0824@2|Bacteria,4NT54@976|Bacteroidetes	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
HKD3_k127_1347683_2	929713.NIASO_13915	4.872e-21	96.0	2EHHG@1|root,33B9E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1347683_1	929703.KE386491_gene1000	7.259e-94	316.0	COG0702@1|root,COG0702@2|Bacteria,4NJCW@976|Bacteroidetes,47Q5P@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,SUKH_5
HKD3_k127_1347683_0	925409.KI911562_gene1393	2.196e-99	327.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IPYF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	kojP	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
HKD3_k127_1350716_1	1239962.C943_01101	4.026e-64	252.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47N98@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
HKD3_k127_1350716_0	1189619.pgond44_14073	1.324e-111	402.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,TPR_12,TPR_7
HKD3_k127_1371426_2	485918.Cpin_0869	2.228e-72	247.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_1371426_1	929713.NIASO_15495	2.574e-120	390.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1IPN9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_1371426_0	925409.KI911562_gene417	5.836e-286	886.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
HKD3_k127_1376829_3	468059.AUHA01000002_gene114	1.091e-120	391.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1IPV7@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_1376829_5	1150600.ADIARSV_3377	4.462e-105	347.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1IPAM@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HKD3_k127_1376829_8	700598.Niako_4328	2.013e-61	218.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_1376829_2	485918.Cpin_4695	1.784e-137	443.0	COG0598@1|root,COG0598@2|Bacteria,4NGM7@976|Bacteroidetes,1IWM4@117747|Sphingobacteriia	976|Bacteroidetes	P	Mg2 transporter protein, CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD3_k127_1376829_0	925409.KI911562_gene2618	1.459e-216	677.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1INU3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_1376829_9	247490.KSU1_C0449	2.179e-38	163.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
HKD3_k127_1376829_10	929713.NIASO_08935	1.096e-35	137.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1IUBT@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD3_k127_1376829_11	929713.NIASO_08930	6.168e-30	119.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1IU0P@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD3_k127_1376829_14	1123248.KB893323_gene1572	6.287e-23	98.0	2ACFD@1|root,31210@2|Bacteria,4PGVP@976|Bacteroidetes,1IUGW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
HKD3_k127_1376829_1	485918.Cpin_3090	3.667e-153	490.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1IPD8@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD3_k127_1376829_4	1123248.KB893314_gene3626	1.737e-106	355.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1IP9Q@117747|Sphingobacteriia	976|Bacteroidetes	H	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HKD3_k127_1376829_7	1123248.KB893314_gene3627	6.73e-83	280.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1IPZJ@117747|Sphingobacteriia	976|Bacteroidetes	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HKD3_k127_1376829_12	925409.KI911562_gene2830	9.796e-27	111.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1IU0K@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HKD3_k127_1376829_6	925409.KI911562_gene2829	4.047e-94	317.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1IP2Y@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_1376829_13	1267211.KI669560_gene2348	1.384e-24	105.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1ITNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
HKD3_k127_1379435_0	1123248.KB893314_gene3477	1.55e-111	371.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1IPQM@117747|Sphingobacteriia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HKD3_k127_1391757_4	1123248.KB893315_gene3138	5.363e-60	219.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,1IYEN@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_1391757_2	700598.Niako_2014	3.597e-75	263.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,1ITG6@117747|Sphingobacteriia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
HKD3_k127_1391757_3	700598.Niako_2015	2.484e-67	232.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HKD3_k127_1391757_0	1267211.KI669560_gene1616	2.008e-210	663.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HKD3_k127_1391757_1	1267211.KI669560_gene2224	5.864e-89	300.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IPQ2@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_1408239_1	1267211.KI669560_gene1618	3.134e-241	754.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1ISNT@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S10	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
HKD3_k127_1408239_2	760192.Halhy_5460	7.219e-59	209.0	COG1917@1|root,COG1917@2|Bacteria,4NUTA@976|Bacteroidetes,1IZA5@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_1408239_0	1122179.KB890431_gene4241	1.268e-249	781.0	COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1408239_3	1267211.KI669560_gene1828	4.648e-17	80.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1IQ2K@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
HKD3_k127_1414430_5	457424.BFAG_01800	2.846e-16	84.0	COG0210@1|root,COG0507@1|root,COG4955@1|root,COG0210@2|Bacteria,COG0507@2|Bacteria,COG4955@2|Bacteria,4NF6J@976|Bacteroidetes,2FM19@200643|Bacteroidia,4ANSF@815|Bacteroidaceae	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	uvrD2	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
HKD3_k127_1414430_0	925409.KI911562_gene55	1.096e-317	994.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IRE6@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_1414430_1	700598.Niako_6960	2.583e-243	757.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
HKD3_k127_1414430_2	1267211.KI669560_gene2766	5.964e-113	367.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
HKD3_k127_1414430_4	1267211.KI669560_gene2766	1.107e-19	88.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
HKD3_k127_1414430_3	1122605.KB893626_gene2720	5.728e-67	235.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
HKD3_k127_1414430_6	925409.KI911562_gene849	5.88e-08	56.0	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1IZ3T@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_1419777_1	700598.Niako_5048	2.547e-52	187.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IURB@117747|Sphingobacteriia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD3_k127_1419777_0	929556.Solca_2958	1.252e-117	389.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQPI@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_1435452_0	1123248.KB893348_gene328	1.238e-256	796.0	COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
HKD3_k127_1435452_1	1034807.FBFL15_0125	1.937e-107	354.0	COG0477@1|root,COG2814@2|Bacteria,4PKJD@976|Bacteroidetes,1IJAV@117743|Flavobacteriia,2NTD2@237|Flavobacterium	976|Bacteroidetes	EGP	LacY proton/sugar symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
HKD3_k127_1459058_2	1382304.JNIL01000001_gene3302	3.639e-30	126.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli	91061|Bacilli	E	allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
HKD3_k127_1459058_0	1121288.AULL01000011_gene1078	3.534e-243	756.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1I067@117743|Flavobacteriia,3ZNS9@59732|Chryseobacterium	976|Bacteroidetes	E	Beta-eliminating lyase	tpl	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
HKD3_k127_1459058_1	945713.IALB_2618	5.15e-221	692.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD3_k127_1472546_0	700598.Niako_2627	0.0	1154.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1IPW9@117747|Sphingobacteriia	976|Bacteroidetes	J	elongation factor G domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_1493036_0	925409.KI911562_gene1618	2.064e-164	522.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1INYI@117747|Sphingobacteriia	976|Bacteroidetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HKD3_k127_1493036_1	1123248.KB893330_gene389	1.382e-120	389.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1INU0@117747|Sphingobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD3_k127_1493858_0	867902.Ornrh_0091	1.046e-263	821.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HKD3_k127_1493858_1	925409.KI911562_gene1624	3.158e-213	670.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPMC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD3_k127_1493858_3	925409.KI911562_gene1625	6.855e-82	279.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1ISNC@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HKD3_k127_1493858_4	1123248.KB893316_gene4655	6.551e-28	117.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1ITNI@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
HKD3_k127_1493858_2	1267211.KI669560_gene1374	1.287e-105	346.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1IPC1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD3_k127_1496092_0	56780.SYN_02880	1.268e-320	998.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,2MQBA@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HKD3_k127_1496092_1	1267211.KI669560_gene407	3.943e-197	624.0	COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1IV0D@117747|Sphingobacteriia	976|Bacteroidetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
HKD3_k127_1496092_2	700598.Niako_6200	1.655e-97	321.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1IVF8@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
HKD3_k127_1496092_4	760192.Halhy_5518	1.125e-24	108.0	2E3V1@1|root,32YSA@2|Bacteria,4NV88@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1496092_3	1122176.KB903535_gene2019	2.929e-37	144.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1IYJ0@117747|Sphingobacteriia	976|Bacteroidetes	Q	Thioesterase superfamily	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
HKD3_k127_152441_1	700598.Niako_1219	9.781e-13	79.0	COG3735@1|root,COG3735@2|Bacteria,4NGNW@976|Bacteroidetes,1IS2W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM GumN	-	-	-	-	-	-	-	-	-	-	-	-	TraB
HKD3_k127_152441_0	745718.JADT01000014_gene233	4.096e-83	279.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD3_k127_152441_2	700598.Niako_5609	1.476e-10	71.0	COG1361@1|root,COG1404@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1IW54@117747|Sphingobacteriia	976|Bacteroidetes	O	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
HKD3_k127_1526765_2	700598.Niako_4420	2.624e-79	274.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1IP6X@117747|Sphingobacteriia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_1526765_1	1461577.CCMH01000005_gene1920	9.933e-85	299.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1HYTA@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
HKD3_k127_1526765_0	929556.Solca_2959	5e-322	1005.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1IQY4@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
HKD3_k127_1540479_1	1239962.C943_01832	4.173e-48	173.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_1540479_5	1123248.KB893370_gene5041	6.174e-24	104.0	COG0607@1|root,COG0607@2|Bacteria,4NUN5@976|Bacteroidetes,1J07C@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_1540479_4	1453500.AT05_01575	2.69e-26	113.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
HKD3_k127_1540479_6	1267211.KI669560_gene1582	6.426e-22	97.0	COG0607@1|root,COG0607@2|Bacteria,4PGNM@976|Bacteroidetes,1ITZD@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1540479_2	485917.Phep_1679	9.167e-38	145.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1ITG8@117747|Sphingobacteriia	976|Bacteroidetes	O	F plasmid transfer operon protein	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD3_k127_1540479_3	388413.ALPR1_06775	1.839e-27	115.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_1540479_0	1267211.KI669560_gene1590	4.581e-132	436.0	COG3203@1|root,COG3203@2|Bacteria,4PMSP@976|Bacteroidetes	976|Bacteroidetes	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
HKD3_k127_1551015_2	388413.ALPR1_16883	3.122e-64	226.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	PKD,Pro_isomerase
HKD3_k127_1551015_4	1267211.KI669560_gene716	9.131e-59	206.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IT1E@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
HKD3_k127_1551015_6	1123248.KB893348_gene103	8.766e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,1IS9P@117747|Sphingobacteriia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD3_k127_1551015_5	700598.Niako_5746	4.664e-47	179.0	COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,1IS07@117747|Sphingobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
HKD3_k127_1551015_8	929713.NIASO_13715	3.632e-20	94.0	COG5652@1|root,COG5652@2|Bacteria,4NXUQ@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD3_k127_1551015_1	1123248.KB893348_gene284	3.196e-82	279.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,1IY3D@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
HKD3_k127_1551015_0	761193.Runsl_1994	2.763e-101	332.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JJV@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD3_k127_1551015_9	1267211.KI669560_gene347	1.512e-12	79.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,Cadherin-like,Calx-beta,Flg_new
HKD3_k127_1551015_3	1094466.KQS_01995	6.263e-61	214.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1I17S@117743|Flavobacteriia,2NVVH@237|Flavobacterium	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
HKD3_k127_1551015_7	1124780.ANNU01000006_gene2817	1.727e-45	171.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
HKD3_k127_1562570_3	525373.HMPREF0766_12714	3.117e-25	109.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,1IYFI@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
HKD3_k127_1562570_0	1454007.JAUG01000002_gene3010	2.253e-56	208.0	2D63Q@1|root,32PM1@2|Bacteria,4PAQB@976|Bacteroidetes,1IX98@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1562570_2	1123248.KB893359_gene2093	8.534e-39	150.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD3_k127_1562570_1	485918.Cpin_6597	7.349e-42	160.0	COG2608@1|root,COG2608@2|Bacteria,4NZ95@976|Bacteroidetes,1IYPT@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HKD3_k127_1562570_4	272559.BF9343_3279	2.003e-06	55.0	2ACE7@1|root,311ZQ@2|Bacteria,4PGUK@976|Bacteroidetes,2FYXK@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1572290_0	1305737.JAFX01000001_gene1039	2.846e-187	593.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,47MJG@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_1572290_1	1121898.Q766_16345	4.639e-105	352.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1HZXZ@117743|Flavobacteriia,2NT8V@237|Flavobacterium	976|Bacteroidetes	S	Iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
HKD3_k127_1578928_2	925409.KI911562_gene782	1.162e-89	303.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,1IRWP@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD3_k127_1578928_3	929713.NIASO_13595	1.707e-55	199.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1ISSQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1578928_1	700598.Niako_6593	1.937e-124	402.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD3_k127_1578928_0	1123248.KB893348_gene214	2.358e-228	721.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HKD3_k127_1594014_1	700598.Niako_4608	9.033e-46	172.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1IQSQ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HKD3_k127_1594014_2	522373.Smlt3132	5.828e-39	159.0	COG1680@1|root,COG1680@2|Bacteria,1RBDE@1224|Proteobacteria,1RYDP@1236|Gammaproteobacteria,1X4U9@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_1594014_0	1123248.KB893345_gene36	3.305e-164	527.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1INW1@117747|Sphingobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD3_k127_1597209_1	1123248.KB893314_gene3570	1.716e-41	155.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1IRTC@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD3_k127_1597209_0	643867.Ftrac_3786	2.34e-159	524.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47P32@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_1600542_1	700598.Niako_0411	1.189e-70	245.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,1IPA5@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_1600542_0	1123248.KB893332_gene2256	1.228e-216	682.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1IP8R@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD3_k127_1606356_0	925409.KI911562_gene2430	0.0	1150.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
HKD3_k127_1606356_1	179408.Osc7112_1245	9.679e-09	57.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1H93R@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_1608473_6	485918.Cpin_0826	3.58e-37	145.0	COG0577@1|root,COG0577@2|Bacteria,4NGDV@976|Bacteroidetes,1IXUG@117747|Sphingobacteriia	976|Bacteroidetes	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1608473_1	1123248.KB893319_gene4042	1.279e-200	635.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1IQGD@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
HKD3_k127_1608473_2	925409.KI911562_gene1095	7.419e-150	486.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1INPG@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2812 DNA polymerase III, gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
HKD3_k127_1608473_4	925409.KI911562_gene1096	8.303e-74	253.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1ISUU@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD3_k127_1608473_3	700598.Niako_5799	1.089e-135	446.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1ISIT@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_1608473_5	700598.Niako_5798	7.043e-68	238.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
HKD3_k127_1608473_0	1123248.KB893386_gene1833	4.096e-216	678.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
HKD3_k127_1618398_1	700598.Niako_4416	9.973e-65	224.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HKD3_k127_1618398_0	700598.Niako_4415	7.23e-85	295.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1IP77@117747|Sphingobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD3_k127_1622236_1	929713.NIASO_13335	4.244e-126	407.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD3_k127_1622236_7	1305737.JAFX01000001_gene1322	3.013e-22	108.0	2B99M@1|root,322KZ@2|Bacteria,4NS5P@976|Bacteroidetes,47QJC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1622236_2	1089547.KB913013_gene90	7.771e-99	357.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,47JQ1@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
HKD3_k127_1622236_8	1123276.KB893312_gene3045	1.768e-13	80.0	COG5662@1|root,COG5662@2|Bacteria,4PPG9@976|Bacteroidetes,47YMZ@768503|Cytophagia	976|Bacteroidetes	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1622236_6	700598.Niako_3037	3.723e-37	148.0	COG1595@1|root,COG1595@2|Bacteria,4NTQN@976|Bacteroidetes	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
HKD3_k127_1622236_5	1267211.KI669560_gene569	2.112e-57	208.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1IYKW@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
HKD3_k127_1622236_3	925409.KI911562_gene1052	1.092e-80	273.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1IRYD@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD3_k127_1622236_0	925409.KI911562_gene1053	1.437e-142	462.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1IQDH@117747|Sphingobacteriia	976|Bacteroidetes	O	protein required for cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
HKD3_k127_1622236_4	925409.KI911562_gene1054	9.267e-79	270.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,1IWMA@117747|Sphingobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD3_k127_1623525_6	362418.IW19_15085	2.438e-22	97.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,2NSN5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD3_k127_1623525_2	694427.Palpr_1039	5.377e-98	328.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,2FQT2@200643|Bacteroidia,22WM3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HKD3_k127_1623525_4	1267211.KI669560_gene658	5.208e-65	228.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,1ISB4@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_1623525_1	926549.KI421517_gene3286	4.259e-110	362.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,47N6P@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD3_k127_1623525_5	391596.PBAL39_18409	1.067e-31	128.0	COG1765@1|root,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1ITGT@117747|Sphingobacteriia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
HKD3_k127_1623525_3	925409.KI911562_gene641	3.235e-75	258.0	COG0431@1|root,COG0431@2|Bacteria,4NNY7@976|Bacteroidetes	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD3_k127_1623525_0	925409.KI911562_gene640	0.0	1000.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
HKD3_k127_1623525_7	1232683.ADIMK_1172	3.476e-06	48.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RR2X@1236|Gammaproteobacteria,4683S@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	nlpC	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HKD3_k127_1628727_0	1356852.N008_09580	3.091e-172	550.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,47M1C@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
HKD3_k127_1628727_1	435591.BDI_1870	6.541e-156	501.0	COG0673@1|root,COG0673@2|Bacteria,4NENY@976|Bacteroidetes,2FWYJ@200643|Bacteroidia,22ZV9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_1628727_2	1123278.KB893389_gene4173	5.133e-91	304.0	COG5285@1|root,COG5285@2|Bacteria,4NEH9@976|Bacteroidetes,47NTV@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
HKD3_k127_1629799_0	925409.KI911562_gene2912	2.359e-137	441.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1IQIJ@117747|Sphingobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
HKD3_k127_1629799_1	925409.KI911562_gene1120	4.588e-113	370.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,1IV8P@117747|Sphingobacteriia	976|Bacteroidetes	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
HKD3_k127_1644324_0	925409.KI911562_gene1392	1.341e-313	979.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_1644324_1	925409.KI911562_gene1391	1.591e-25	110.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_1645575_0	1123248.KB893386_gene1983	0.0	1330.0	COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,1IV8M@117747|Sphingobacteriia	976|Bacteroidetes	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HKD3_k127_1645575_1	925409.KI911562_gene289	1.508e-83	282.0	COG0491@1|root,COG0491@2|Bacteria,4NINV@976|Bacteroidetes,1IS2X@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_164677_2	1094466.KQS_06625	8.812e-18	89.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HWJR@117743|Flavobacteriia,2NSNJ@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD3_k127_164677_0	925409.KI911562_gene387	9.652e-201	631.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_164677_1	313606.M23134_05036	2.099e-65	232.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47NEB@768503|Cytophagia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
HKD3_k127_1647897_0	1122176.KB903532_gene2525	1.915e-39	164.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,1IWFT@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
HKD3_k127_1647897_2	925409.KI911562_gene674	5.131e-10	65.0	2AFQJ@1|root,315SF@2|Bacteria,4NZE3@976|Bacteroidetes,1J018@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1647897_1	1121957.ATVL01000007_gene1650	1.039e-38	147.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_164933_0	1408433.JHXV01000011_gene2075	2.566e-117	390.0	COG0577@1|root,COG0577@2|Bacteria,4NF60@976|Bacteroidetes,1HZ48@117743|Flavobacteriia,2PBC8@246874|Cryomorphaceae	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_164933_2	1121898.Q766_08220	5.557e-59	211.0	COG1136@1|root,COG1136@2|Bacteria,4NNS2@976|Bacteroidetes,1I29Q@117743|Flavobacteriia,2NUBS@237|Flavobacterium	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_164933_3	1250232.JQNJ01000001_gene1069	1.137e-56	205.0	28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,1HZ05@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_164933_1	1347342.BN863_13630	1.689e-99	329.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HYU9@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1658315_1	485918.Cpin_4000	2.621e-63	226.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,1IPDU@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
HKD3_k127_1658315_0	1267211.KI669560_gene2082	4.701e-151	484.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
HKD3_k127_1668266_5	1123248.KB893314_gene3693	9.968e-35	135.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1IUIV@117747|Sphingobacteriia	976|Bacteroidetes	S	Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
HKD3_k127_1668266_2	925409.KI911562_gene2112	2.344e-76	261.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1IP1V@117747|Sphingobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
HKD3_k127_1668266_3	1267211.KI669560_gene1646	1.506e-58	214.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes	976|Bacteroidetes	S	esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_1668266_0	1123248.KB893323_gene1601	5.24e-186	589.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1INZR@117747|Sphingobacteriia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_1668266_4	1123248.KB893323_gene1602	1.962e-40	161.0	COG1266@1|root,COG1266@2|Bacteria,4NHRW@976|Bacteroidetes,1IYXV@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_1668266_1	929556.Solca_2958	4.488e-166	532.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQPI@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_1671429_1	388413.ALPR1_05670	1.873e-101	335.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HKD3_k127_1671429_2	700598.Niako_5084	2.891e-71	243.0	COG1247@1|root,COG1247@2|Bacteria,4PM4N@976|Bacteroidetes,1ISGA@117747|Sphingobacteriia	976|Bacteroidetes	M	Gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_1671429_0	984262.SGRA_2537	2.004e-107	374.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_1691484_0	1123248.KB893318_gene4199	4.051e-166	537.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1IP68@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HKD3_k127_1691484_1	929713.NIASO_01165	1.039e-47	173.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1IRVT@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HKD3_k127_1696112_0	929562.Emtol_0436	1.675e-243	764.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD3_k127_1707521_0	867902.Ornrh_1424	1.076e-189	607.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208,ko:K21575	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N,DUF3459
HKD3_k127_1731397_10	700598.Niako_2149	1.357e-30	123.0	COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1IP6Q@117747|Sphingobacteriia	976|Bacteroidetes	G	glucose-1-phosphate adenylyltransferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD3_k127_1731397_1	1123248.KB893315_gene3009	2.088e-213	671.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1IQCB@117747|Sphingobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HKD3_k127_1731397_0	1267211.KI669560_gene1438	1.559e-255	798.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
HKD3_k127_1731397_3	700598.Niako_2152	2.574e-149	479.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IWBC@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD3_k127_1731397_8	1123248.KB893323_gene1617	7.589e-40	154.0	2DKFZ@1|root,309D6@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HKD3_k127_1731397_5	700598.Niako_2153	7.66e-99	332.0	COG4632@1|root,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes,1ITPU@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,fn3
HKD3_k127_1731397_2	700598.Niako_2154	2.062e-166	526.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HKD3_k127_1731397_6	925409.KI911562_gene2627	2.03e-84	288.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1731397_9	925409.KI911562_gene2628	5.573e-38	146.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1ISTX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
HKD3_k127_1731397_4	1123248.KB893359_gene2142	7.446e-146	473.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
HKD3_k127_1731397_7	925409.KI911562_gene2630	1.095e-42	158.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1ISD6@117747|Sphingobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HKD3_k127_1734333_2	929556.Solca_4018	1.587e-07	55.0	2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes,1IU6D@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD3_k127_1734333_1	485918.Cpin_4286	7.245e-115	381.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,1IR8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
HKD3_k127_1734333_0	1123248.KB893322_gene595	2.233e-161	518.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1INS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
HKD3_k127_1742926_3	313606.M23134_08367	9.58e-36	139.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
HKD3_k127_1742926_0	1229487.AMYW01000030_gene3640	0.0	1033.0	COG3408@1|root,COG3408@2|Bacteria,4NFMY@976|Bacteroidetes,1I7ZZ@117743|Flavobacteriia,2NVTS@237|Flavobacterium	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1742926_2	1216967.L100_13724	3.05e-38	149.0	COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes,1I2TS@117743|Flavobacteriia	976|Bacteroidetes	J	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_1742926_1	1120966.AUBU01000005_gene3744	2.111e-72	246.0	COG1051@1|root,COG1051@2|Bacteria,4NNUR@976|Bacteroidetes,47PU7@768503|Cytophagia	976|Bacteroidetes	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD3_k127_1742926_4	929556.Solca_4018	1.811e-35	144.0	2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes,1IU6D@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD3_k127_1742926_5	1123248.KB893354_gene2292	2.469e-32	126.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,1IR8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
HKD3_k127_1747479_2	700598.Niako_6519	1.669e-76	263.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1IV4X@117747|Sphingobacteriia	976|Bacteroidetes	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_1747479_1	1434325.AZQN01000001_gene665	1.975e-110	363.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_1747479_0	1434325.AZQN01000001_gene666	2.734e-202	633.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_1752954_1	1121859.KB890750_gene383	2.426e-109	366.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_1752954_3	1123248.KB893321_gene547	1.461e-64	226.0	COG0652@1|root,COG0652@2|Bacteria,4NRWP@976|Bacteroidetes	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HKD3_k127_1752954_4	700598.Niako_3944	7.775e-50	184.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,1IT28@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
HKD3_k127_1752954_0	1122621.ATZA01000009_gene323	1.122e-242	764.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPJF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_1752954_2	1123248.KB893337_gene2559	2.73e-103	345.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1IPT7@117747|Sphingobacteriia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
HKD3_k127_1759647_2	485917.Phep_2269	3.357e-33	132.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1IUW0@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphotransferase enzyme family	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
HKD3_k127_1759647_0	1341155.FSS13T_18150	1.809e-111	369.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HWJR@117743|Flavobacteriia,2NSNJ@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD3_k127_1759647_1	1121890.AUDO01000009_gene134	3.045e-36	139.0	COG3291@1|root,COG3291@2|Bacteria,4NMA6@976|Bacteroidetes,1IJ6Q@117743|Flavobacteriia,2P0JV@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD3_k127_1776698_0	1267211.KI669560_gene2783	6.616e-276	867.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1IQ4I@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
HKD3_k127_1776698_3	1443665.JACA01000001_gene2643	9.171e-12	71.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia,2YJE5@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1776698_1	1131812.JQMS01000001_gene765	8.249e-18	88.0	2BK9M@1|root,32EPT@2|Bacteria,4NQGA@976|Bacteroidetes,1I2SP@117743|Flavobacteriia,2NWJ8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1776698_2	1279009.ADICEAN_04018	1.142e-16	83.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47JN7@768503|Cytophagia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
HKD3_k127_1778583_1	485918.Cpin_2010	8.517e-82	281.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1IUSP@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_1778583_3	313606.M23134_02261	7.059e-39	150.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD3_k127_1778583_0	925409.KI911562_gene2869	5.09e-97	323.0	COG2227@1|root,COG2227@2|Bacteria,4PKUR@976|Bacteroidetes,1J0TH@117747|Sphingobacteriia	976|Bacteroidetes	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
HKD3_k127_1778583_2	1267211.KI669560_gene1019	5.019e-46	174.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1IZ7F@117747|Sphingobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
HKD3_k127_1826881_2	1279009.ADICEAN_00929	8.043e-43	160.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47N0R@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_1826881_0	761193.Runsl_1946	3.416e-308	966.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_1826881_1	641526.ADIWIN_1093	2.961e-243	775.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_1826881_3	743722.Sph21_2610	5.088e-27	112.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INWS@117747|Sphingobacteriia	976|Bacteroidetes	V	InterPro IPR003838	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_1829552_0	1123248.KB893331_gene3753	2.484e-127	418.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1INYY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
HKD3_k127_1829552_1	1267211.KI669560_gene370	4.554e-87	290.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1IQ7Q@117747|Sphingobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD3_k127_183292_2	1144313.PMI10_02610	1.633e-57	205.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1I040@117743|Flavobacteriia,2NUS5@237|Flavobacterium	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HKD3_k127_183292_1	1144313.PMI10_02609	4.68e-106	353.0	COG1305@1|root,COG1305@2|Bacteria,4NF4N@976|Bacteroidetes,1HZS1@117743|Flavobacteriia,2NTCB@237|Flavobacterium	976|Bacteroidetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
HKD3_k127_183292_0	925409.KI911562_gene1527	2.224e-191	606.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD3_k127_1842216_2	1173025.GEI7407_1929	3.496e-13	76.0	COG0680@1|root,COG0680@2|Bacteria,1G7PP@1117|Cyanobacteria,1HC58@1150|Oscillatoriales	1117|Cyanobacteria	C	hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1842216_1	929562.Emtol_1904	2.022e-89	304.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,47N3H@768503|Cytophagia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_1842216_0	1123278.KB893564_gene2580	3.567e-153	495.0	COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_1844685_4	743722.Sph21_1368	7.772e-14	71.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1INZC@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HKD3_k127_1844685_0	1358423.N180_09540	2.76e-175	563.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1INY6@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HKD3_k127_1844685_1	1123248.KB893348_gene125	3.519e-107	352.0	COG0546@1|root,COG0546@2|Bacteria,4PM7Q@976|Bacteroidetes,1J0KR@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HKD3_k127_1844685_3	700598.Niako_6623	7.792e-68	238.0	COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_1844685_2	1122605.KB893647_gene275	3.446e-96	329.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes,1IPAQ@117747|Sphingobacteriia	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD3_k127_1861174_0	700598.Niako_2097	8.64e-158	502.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD3_k127_1861174_3	1229487.AMYW01000022_gene78	7.222e-38	148.0	2CSP1@1|root,32SRI@2|Bacteria,4NT1E@976|Bacteroidetes,1I3GB@117743|Flavobacteriia,2NW4N@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1861174_1	1089547.KB913013_gene3945	4.474e-62	219.0	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,47QBA@768503|Cytophagia	976|Bacteroidetes	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
HKD3_k127_1861174_2	1237149.C900_01393	3.459e-61	225.0	COG0683@1|root,COG0683@2|Bacteria,4NKE7@976|Bacteroidetes	976|Bacteroidetes	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD3_k127_1886883_1	1121288.AULL01000019_gene1479	2.603e-69	257.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HZJX@117743|Flavobacteriia,3ZUJA@59732|Chryseobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
HKD3_k127_1886883_0	1267211.KI669560_gene1988	1.545e-163	516.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_1886883_2	1123248.KB893315_gene3145	1.538e-42	156.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_1887382_1	925409.KI911562_gene1016	3.901e-210	662.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1IPWZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
HKD3_k127_1887382_2	925409.KI911562_gene1015	4.3e-187	591.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1J0U0@117747|Sphingobacteriia	976|Bacteroidetes	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
HKD3_k127_1887382_3	925409.KI911562_gene1014	1.68e-72	256.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
HKD3_k127_1887382_7	643867.Ftrac_2337	2.388e-22	97.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HKD3_k127_1887382_5	1500281.JQKZ01000034_gene139	9.822e-49	181.0	COG1331@1|root,COG1331@2|Bacteria,4NMU8@976|Bacteroidetes,1IK15@117743|Flavobacteriia,3ZUQ8@59732|Chryseobacterium	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_2,Thioredoxin_7
HKD3_k127_1887382_6	491205.JARQ01000007_gene2951	2.673e-24	109.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1I0XW@117743|Flavobacteriia,3ZP0H@59732|Chryseobacterium	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
HKD3_k127_1887382_0	925409.KI911562_gene299	1.392e-224	707.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HKD3_k127_1887382_4	234267.Acid_4804	5.238e-66	233.0	COG2008@1|root,COG2008@2|Bacteria,3Y7Q8@57723|Acidobacteria	57723|Acidobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD3_k127_1892764_1	1347342.BN863_9110	8.695e-08	57.0	2A3Y3@1|root,30SGF@2|Bacteria,4NZA3@976|Bacteroidetes,1IIYA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1892764_0	314278.NB231_01773	1.763e-177	561.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1WWMT@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_1905689_1	1233951.IO90_15760	1.902e-151	490.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,4NEVK@976|Bacteroidetes,1HYB7@117743|Flavobacteriia,3HGUX@358033|Chryseobacterium	976|Bacteroidetes	G	Maltogenic Amylase, C-terminal domain	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
HKD3_k127_1905689_2	925409.KI911562_gene1821	2.09e-131	430.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1IQHN@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD3_k127_1905689_0	925409.KI911562_gene2834	5.066e-201	634.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD3_k127_1905689_3	1123248.KB893348_gene361	8.057e-114	387.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_1907654_1	925409.KI911562_gene2495	1.104e-133	432.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
HKD3_k127_1907654_0	700598.Niako_0920	1.755e-135	437.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_1907654_3	926549.KI421517_gene1465	1.255e-30	134.0	COG2353@1|root,COG2353@2|Bacteria,4PNPU@976|Bacteroidetes,47YDS@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1907654_4	243230.DR_0242	9.634e-13	75.0	COG3502@1|root,COG3502@2|Bacteria,1WMXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
HKD3_k127_1907654_2	700598.Niako_4503	2.074e-38	150.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1IQ18@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HKD3_k127_1933282_5	491205.JARQ01000003_gene2042	9.564e-09	56.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia,3ZQ5P@59732|Chryseobacterium	976|Bacteroidetes	S	nucleotide pyrophosphatase	pafA	GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD3_k127_1933282_1	1123248.KB893323_gene1653	8.643e-102	340.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
HKD3_k127_1933282_4	925409.KI911562_gene2031	1.492e-73	252.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_1933282_0	925409.KI911562_gene2033	5.321e-201	633.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1IQ2Y@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
HKD3_k127_1933282_3	925409.KI911562_gene2330	1.517e-83	282.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
HKD3_k127_1933282_2	700598.Niako_1029	4.704e-92	310.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IWD6@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_1949843_1	1123248.KB893321_gene534	3.566e-67	231.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1IQ8A@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
HKD3_k127_1949843_2	1127692.HMPREF9075_01140	1.616e-25	113.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia,1ERZI@1016|Capnocytophaga	976|Bacteroidetes	H	5-formyltetrahydrofolate cyclo-ligase	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HKD3_k127_1949843_0	1267211.KI669560_gene1778	1.619e-78	266.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1ISB1@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA methyltransferase, RsmD	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD3_k127_1950932_3	925409.KI911562_gene170	7.546e-106	350.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_1950932_1	1123248.KB893386_gene1867	6.728e-224	706.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1IQK8@117747|Sphingobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD3_k127_1950932_0	1267211.KI669560_gene2162	0.0	1034.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HKD3_k127_1950932_6	797304.Natgr_3254	6.471e-07	61.0	COG2244@1|root,arCOG02209@2157|Archaea,2XVSG@28890|Euryarchaeota,23TNY@183963|Halobacteria	183963|Halobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_1950932_2	700598.Niako_2016	1.067e-136	443.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD3_k127_1950932_5	1123248.KB893337_gene2513	4.337e-61	224.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IQ1U@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
HKD3_k127_1950932_4	1237149.C900_03603	9.429e-73	259.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,47KE5@768503|Cytophagia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
HKD3_k127_196236_1	697282.Mettu_1528	2.624e-21	96.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XE2H@135618|Methylococcales	135618|Methylococcales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_196236_0	697282.Mettu_1529	5.592e-235	731.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XDU6@135618|Methylococcales	135618|Methylococcales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
HKD3_k127_197897_4	929713.NIASO_02595	4.06e-102	340.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD3_k127_197897_5	743722.Sph21_3230	4.536e-91	306.0	COG0705@1|root,COG0705@2|Bacteria,4NJG9@976|Bacteroidetes,1J16X@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_197897_10	1122176.KB903542_gene389	8.695e-58	206.0	COG1437@1|root,COG1437@2|Bacteria,4NQQK@976|Bacteroidetes	976|Bacteroidetes	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
HKD3_k127_197897_8	925409.KI911562_gene1891	7.015e-66	229.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1IRYB@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HKD3_k127_197897_2	700598.Niako_4456	2.655e-179	565.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1IQ3D@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HKD3_k127_197897_3	485918.Cpin_1641	3.404e-107	349.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD3_k127_197897_6	1122605.KB893647_gene436	2.857e-68	235.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1ISSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HKD3_k127_197897_9	929713.NIASO_12345	2.051e-63	219.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HKD3_k127_197897_13	700598.Niako_4460	7.921e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1IUD9@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HKD3_k127_197897_12	925409.KI911562_gene1886	5.097e-37	140.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1IT95@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HKD3_k127_197897_0	1123248.KB893381_gene1048	1.293e-297	940.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,1IQHQ@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_197897_1	929713.NIASO_06925	3.646e-225	700.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1IPEN@117747|Sphingobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
HKD3_k127_197897_11	1216967.L100_10294	2.022e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,4NSYC@976|Bacteroidetes,1I46X@117743|Flavobacteriia,34RI1@308865|Elizabethkingia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,NUDIX
HKD3_k127_197897_7	1346330.M472_17610	5.887e-67	231.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1IRXF@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD3_k127_198083_2	1121957.ATVL01000007_gene1831	2.225e-137	443.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_198083_5	1123248.KB893315_gene3150	1.528e-77	264.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1J0TI@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_198083_0	1123248.KB893315_gene3149	8.505e-187	589.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HKD3_k127_198083_6	925409.KI911562_gene1679	8.662e-52	190.0	COG2808@1|root,COG2808@2|Bacteria,4NINW@976|Bacteroidetes,1IYCA@117747|Sphingobacteriia	976|Bacteroidetes	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
HKD3_k127_198083_8	983544.Lacal_0272	2.033e-23	106.0	COG5642@1|root,COG5642@2|Bacteria,4NRNB@976|Bacteroidetes,1IJ3B@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
HKD3_k127_198083_7	762903.Pedsa_0161	6.426e-30	126.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,1ITH9@117747|Sphingobacteriia	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
HKD3_k127_198083_3	1267211.KI669560_gene1992	3.675e-115	377.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1IQ9S@117747|Sphingobacteriia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD3_k127_198083_4	1123248.KB893318_gene4190	2.939e-94	313.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1ISGF@117747|Sphingobacteriia	976|Bacteroidetes	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
HKD3_k127_198083_1	1123248.KB893318_gene4191	3.436e-162	521.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1IPU7@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HKD3_k127_1998726_1	269798.CHU_1515	2.62e-59	210.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,47PXK@768503|Cytophagia	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD3_k127_1998726_0	391596.PBAL39_18774	3.691e-131	423.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
HKD3_k127_1998726_2	1123248.KB893315_gene3111	2.326e-47	171.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1IYKS@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD3_k127_1998726_3	493475.GARC_5080	6.187e-06	53.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 31 family	malZ	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527	2.4.1.161,3.2.1.177,3.2.1.20	ko:K01187,ko:K01811,ko:K18820	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	CBM_20,DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14
HKD3_k127_200223_3	1229276.DI53_2897	2.983e-08	58.0	COG3735@1|root,COG3735@2|Bacteria,4NPI6@976|Bacteroidetes,1ISGI@117747|Sphingobacteriia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
HKD3_k127_200223_2	243233.MCA0768	1.673e-108	360.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,1XDK5@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD3_k127_200223_0	760192.Halhy_6513	0.0	1724.0	COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HKD3_k127_200223_1	880070.Cycma_4553	5.753e-207	657.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,4NM18@976|Bacteroidetes,47XKA@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
HKD3_k127_2006784_3	925409.KI911562_gene170	1.427e-104	346.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_2006784_5	1123248.KB893386_gene1864	7.56e-47	173.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1ITU7@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
HKD3_k127_2006784_0	1267211.KI669560_gene2528	0.0	1155.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
HKD3_k127_2006784_4	700598.Niako_0140	1.197e-92	310.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1IQDU@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD3_k127_2006784_2	925409.KI911562_gene52	5.534e-115	376.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD3_k127_2006784_1	925409.KI911562_gene1535	2.815e-122	394.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
HKD3_k127_2009469_2	1196083.SALWKB12_0353	7.49e-40	158.0	2EAQY@1|root,334T6@2|Bacteria,1NFJT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2009469_1	321327.CYA_1413	2.286e-41	163.0	2DBB9@1|root,2Z86U@2|Bacteria,1G32F@1117|Cyanobacteria,1H0BP@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2009469_0	1123248.KB893332_gene2256	2.178e-105	348.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1IP8R@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD3_k127_2013792_0	1267211.KI669560_gene373	6.25e-128	411.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
HKD3_k127_2013792_1	1121887.AUDK01000010_gene1413	1.222e-30	126.0	2C82G@1|root,32RK9@2|Bacteria,4NSXV@976|Bacteroidetes,1I466@117743|Flavobacteriia,2NX9M@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
HKD3_k127_2013792_2	1122621.ATZA01000047_gene3383	7.111e-20	104.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_2035797_0	925409.KI911562_gene1391	1.029e-154	499.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_2035797_2	925409.KI911562_gene1390	1.371e-58	214.0	2F80M@1|root,340E7@2|Bacteria,4P4VX@976|Bacteroidetes,1IYG6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2035797_1	1267211.KI669560_gene1024	9.017e-132	430.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IWKA@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
HKD3_k127_2043519_0	714943.Mucpa_0244	0.0	1242.0	COG1112@1|root,COG1198@1|root,COG1112@2|Bacteria,COG1198@2|Bacteria,4NF2S@976|Bacteroidetes,1IQ91@117747|Sphingobacteriia	976|Bacteroidetes	L	Protein of unknown function (DUF4011)	recD2_4	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,WGR
HKD3_k127_2070155_2	1034807.FBFL15_3059	9.247e-84	288.0	COG0697@1|root,COG0697@2|Bacteria,4NK8U@976|Bacteroidetes,1I01E@117743|Flavobacteriia,2NV5M@237|Flavobacterium	976|Bacteroidetes	EG	drug metabolite-transporting permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_2070155_1	1123248.KB893325_gene1168	1.424e-88	304.0	COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes,1J0CK@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_2070155_0	925409.KI911562_gene437	4.001e-186	605.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1IPE9@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
HKD3_k127_2070155_3	925409.KI911562_gene438	1.017e-51	185.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1IT3H@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HKD3_k127_2084233_1	1250232.JQNJ01000001_gene3736	1.741e-70	244.0	COG1052@1|root,COG1052@2|Bacteria,4NIHV@976|Bacteroidetes,1HX33@117743|Flavobacteriia	976|Bacteroidetes	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_2084233_0	1123248.KB893328_gene936	3.547e-227	715.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_2117686_2	1121912.AUHD01000005_gene1843	9.808e-81	276.0	COG0729@1|root,COG0729@2|Bacteria,4PPA8@976|Bacteroidetes	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
HKD3_k127_2117686_0	1347342.BN863_10510	1.306e-148	481.0	COG3746@1|root,COG3746@2|Bacteria,4NK5I@976|Bacteroidetes	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
HKD3_k127_2117686_1	866536.Belba_1629	8.472e-126	416.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M3Z@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_2120794_2	290317.Cpha266_1928	5.901e-71	248.0	COG3015@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,NlpE
HKD3_k127_2120794_3	614083.AWQR01000041_gene797	4.164e-61	214.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VU64@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
HKD3_k127_2120794_1	1086011.HJ01_03312	3.26e-72	251.0	COG0500@1|root,COG0500@2|Bacteria,4PM8S@976|Bacteroidetes,1IJMZ@117743|Flavobacteriia,2P0RG@237|Flavobacterium	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31,NodS
HKD3_k127_2120794_0	1123057.P872_10555	3.36e-80	272.0	COG0664@1|root,COG0664@2|Bacteria,4NSMK@976|Bacteroidetes,47PHC@768503|Cytophagia	976|Bacteroidetes	T	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_2120794_4	1239962.C943_03447	2.847e-39	147.0	COG0477@1|root,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,47KR8@768503|Cytophagia	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_213019_2	616991.JPOO01000003_gene2079	1.794e-88	295.0	COG1082@1|root,COG1082@2|Bacteria,4NFKF@976|Bacteroidetes,1HZU8@117743|Flavobacteriia,23GME@178469|Arenibacter	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_213019_1	1239962.C943_02598	1.462e-92	309.0	COG2133@1|root,COG2133@2|Bacteria,4NIMV@976|Bacteroidetes,47PH9@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_213019_0	1288963.ADIS_1886	4.305e-108	352.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_2133917_1	504472.Slin_4697	4.738e-11	68.0	COG0607@1|root,COG1996@1|root,COG0607@2|Bacteria,COG1996@2|Bacteria,4PIDM@976|Bacteroidetes,47X19@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_2133917_0	1123248.KB893385_gene4734	3.579e-215	696.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_2136106_2	1168034.FH5T_16620	6.128e-27	113.0	COG2249@1|root,COG2249@2|Bacteria,4NGF7@976|Bacteroidetes,2FP6B@200643|Bacteroidia	976|Bacteroidetes	S	Flavodoxin-like protein	ywrO	-	-	ko:K11748	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
HKD3_k127_2136106_0	700598.Niako_4180	2.822e-232	734.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,1IRGD@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
HKD3_k127_2136106_1	760192.Halhy_1199	2.02e-88	302.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,1IVNV@117747|Sphingobacteriia	976|Bacteroidetes	J	Putative GTP-binding controlling metal-binding	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HKD3_k127_2136106_3	886293.Sinac_0801	6.764e-08	59.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
HKD3_k127_2145494_0	509635.N824_13650	6.443e-138	446.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1IPY6@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_2145494_2	1341181.FLJC2902T_19620	2.954e-51	188.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,1I232@117743|Flavobacteriia,2NWA0@237|Flavobacterium	976|Bacteroidetes	S	Acetyltransferase	-	-	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,NAD_binding_9
HKD3_k127_2145494_1	883096.HMPREF9699_01730	6.992e-89	297.0	COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,1HWQ3@117743|Flavobacteriia	976|Bacteroidetes	M	Transferase	wcgN	-	2.7.8.36	ko:K15915	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
HKD3_k127_2160763_3	509635.N824_27520	3.384e-30	120.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1IS1P@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD3_k127_2160763_1	929713.NIASO_16405	1.255e-148	479.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,1IPIR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Alanine racemase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
HKD3_k127_2160763_0	471854.Dfer_0448	9.24e-213	662.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,47JHR@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD3_k127_2160763_2	700598.Niako_4718	2.258e-126	409.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1INRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
HKD3_k127_217338_3	925409.KI911562_gene2632	1.062e-58	208.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1ISN3@117747|Sphingobacteriia	976|Bacteroidetes	S	haloacid dehalogenase-like hydrolase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
HKD3_k127_217338_5	925409.KI911562_gene2633	5.467e-41	153.0	COG2975@1|root,COG2975@2|Bacteria,4NSUG@976|Bacteroidetes,1ITCB@117747|Sphingobacteriia	976|Bacteroidetes	S	FeS assembly protein IscX	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
HKD3_k127_217338_4	1123248.KB893337_gene2550	1.862e-54	192.0	COG0633@1|root,COG0633@2|Bacteria,4NTVJ@976|Bacteroidetes,1ITJK@117747|Sphingobacteriia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
HKD3_k127_217338_1	700598.Niako_1512	7.729e-67	236.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1IRXA@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HKD3_k127_217338_2	1267211.KI669560_gene1427	7.39e-60	218.0	COG2267@1|root,COG2267@2|Bacteria,4PKB9@976|Bacteroidetes,1IZ4H@117747|Sphingobacteriia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD3_k127_217338_0	1123248.KB893323_gene1654	0.0	1170.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
HKD3_k127_2187409_0	860228.Ccan_10730	3.251e-265	826.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia,1EREB@1016|Capnocytophaga	976|Bacteroidetes	H	Formyltetrahydrofolate synthetase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HKD3_k127_2187409_1	1123248.KB893322_gene598	5.771e-41	156.0	COG2318@1|root,COG2318@2|Bacteria,4NPSF@976|Bacteroidetes	976|Bacteroidetes	S	Pfam DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
HKD3_k127_2187409_2	925409.KI911562_gene1496	2.808e-06	57.0	COG0626@1|root,COG0626@2|Bacteria,4NJRK@976|Bacteroidetes,1IP3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_2201391_1	700598.Niako_6277	3.353e-153	492.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1IQVW@117747|Sphingobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2201391_3	1237149.C900_03604	2.545e-55	205.0	COG2067@1|root,COG2067@2|Bacteria,4NVCH@976|Bacteroidetes,47SCX@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_2201391_2	1123248.KB893319_gene4041	2.615e-78	267.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1IQWM@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
HKD3_k127_2201391_0	925409.KI911562_gene1050	1.15e-154	492.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1IRY2@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
HKD3_k127_2201391_4	443143.GM18_2042	6.459e-19	96.0	COG0671@1|root,COG0671@2|Bacteria,1QUKE@1224|Proteobacteria,42XAW@68525|delta/epsilon subdivisions,2WT5A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_2217799_3	485918.Cpin_0825	9.76e-08	57.0	COG1136@1|root,COG1136@2|Bacteria,4NN5Z@976|Bacteroidetes,1IXVG@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_2217799_0	929562.Emtol_0756	7.308e-68	233.0	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,47PW5@768503|Cytophagia	976|Bacteroidetes	G	MGS-like domain	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HKD3_k127_2217799_2	1227739.Hsw_0851	2.944e-16	79.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47K15@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_2236451_3	1356852.N008_09345	1.513e-22	104.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4114,Lactonase,Phage-tail_3
HKD3_k127_2236451_1	700598.Niako_3448	2.966e-36	146.0	COG1595@1|root,COG1595@2|Bacteria,4NRBP@976|Bacteroidetes	976|Bacteroidetes	K	RNA polymerase, sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_2236451_0	485918.Cpin_5148	4.598e-66	240.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,1IS0W@117747|Sphingobacteriia	976|Bacteroidetes	PT	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_2236451_2	714943.Mucpa_4768	7.85e-28	121.0	COG4796@1|root,COG4796@2|Bacteria,4PMPT@976|Bacteroidetes,1IR9G@117747|Sphingobacteriia	976|Bacteroidetes	U	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_2241839_0	485917.Phep_2046	7.452e-158	507.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1IR0G@117747|Sphingobacteriia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
HKD3_k127_2241839_2	926566.Terro_4014	1.874e-35	144.0	2DMXX@1|root,32UAZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2241839_1	468059.AUHA01000002_gene17	4.342e-137	447.0	COG1305@1|root,COG1305@2|Bacteria,4NI22@976|Bacteroidetes,1INVZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2273820_0	1267211.KI669560_gene2746	1.076e-110	369.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1IPM6@117747|Sphingobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
HKD3_k127_2273820_1	1296416.JACB01000029_gene4207	1.44e-52	193.0	2C0BR@1|root,32Z3H@2|Bacteria,4NVDW@976|Bacteroidetes,1II77@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
HKD3_k127_2275770_1	743722.Sph21_2610	2.108e-207	670.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INWS@117747|Sphingobacteriia	976|Bacteroidetes	V	InterPro IPR003838	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_2275770_0	1123277.KB893172_gene538	3.917e-317	990.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_2275770_3	714943.Mucpa_2151	2.687e-126	410.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,1INQS@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_2275770_2	714943.Mucpa_2150	2.526e-185	587.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1IPZS@117747|Sphingobacteriia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HKD3_k127_2279256_9	925409.KI911562_gene1880	1.036e-24	109.0	COG0457@1|root,COG0457@2|Bacteria	925409.KI911562_gene1880|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2279256_4	925409.KI911562_gene1879	8.445e-97	321.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1IPVS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HKD3_k127_2279256_7	1123248.KB893316_gene4517	1.304e-52	189.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1IU9P@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART PUR-alpha beta gamma DNA RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
HKD3_k127_2279256_1	1267211.KI669560_gene2276	2.245e-235	731.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HKD3_k127_2279256_0	929556.Solca_1053	1.558e-308	971.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,4NEK3@976|Bacteroidetes,1INMR@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
HKD3_k127_2279256_6	925409.KI911562_gene2346	4.63e-58	207.0	COG0454@1|root,COG0456@2|Bacteria,4NNG9@976|Bacteroidetes,1ISS7@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD3_k127_2279256_12	926551.KB900737_gene423	2.06e-09	66.0	COG3047@1|root,COG3047@2|Bacteria,4PN0K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2279256_5	1123248.KB893314_gene3270	1.714e-63	224.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1IS5M@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
HKD3_k127_2279256_10	435591.BDI_0004	2.275e-22	102.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,22YMZ@171551|Porphyromonadaceae	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HKD3_k127_2279256_8	700598.Niako_0373	4.412e-35	138.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1IT7G@117747|Sphingobacteriia	976|Bacteroidetes	M	peptidase M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_2279256_2	1123248.KB893315_gene3124	4.941e-207	678.0	COG0457@1|root,COG1729@1|root,COG3147@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3147@2|Bacteria,4NDV9@976|Bacteroidetes,1IQQP@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
HKD3_k127_2279256_3	1267211.KI669560_gene2282	4.012e-205	651.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_2307860_4	1121904.ARBP01000005_gene4689	1.138e-61	220.0	COG0451@1|root,COG0451@2|Bacteria,4NHED@976|Bacteroidetes,47MS2@768503|Cytophagia	976|Bacteroidetes	GM	Male sterility protein	-	-	5.1.3.26	ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
HKD3_k127_2307860_3	156889.Mmc1_2423	1.818e-70	241.0	COG0110@1|root,COG0110@2|Bacteria,1RDCP@1224|Proteobacteria,2TWW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD3_k127_2307860_1	1121904.ARBP01000005_gene4690	1.429e-118	394.0	COG0438@1|root,COG0438@2|Bacteria,4NI16@976|Bacteroidetes,47T1W@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_2307860_0	1121904.ARBP01000005_gene4693	1.792e-138	453.0	COG1541@1|root,COG1541@2|Bacteria,4NFFT@976|Bacteroidetes	976|Bacteroidetes	H	COG1541 Coenzyme F390 synthetase	capK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
HKD3_k127_2307860_2	1131812.JQMS01000001_gene175	6.473e-97	327.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2NVCP@237|Flavobacterium	976|Bacteroidetes	E	Glutamine amidotransferase domain	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_2358340_1	700598.Niako_5607	6.592e-134	436.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1ISDW@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
HKD3_k127_2358340_0	1288963.ADIS_1886	6.828e-156	501.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_2382565_0	929713.NIASO_20615	1.534e-203	637.0	COG3278@1|root,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IPJV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM cytochrome c oxidase subunit I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
HKD3_k127_2382565_1	929713.NIASO_20610	1.142e-153	491.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,4NEM7@976|Bacteroidetes,1IW5F@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3,FixO
HKD3_k127_2382565_5	929713.NIASO_20605	1.955e-25	107.0	2E58U@1|root,33018@2|Bacteria,4NVWZ@976|Bacteroidetes,1IZ66@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2382565_3	929713.NIASO_20600	8.761e-63	217.0	COG2010@1|root,COG2010@2|Bacteria,4NQNG@976|Bacteroidetes,1IXSG@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2382565_4	1123248.KB893326_gene1359	2.785e-51	186.0	COG2346@1|root,COG2346@2|Bacteria,4NQCV@976|Bacteroidetes,1IT6Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD3_k127_2382565_6	1123248.KB893326_gene1355	2.59e-21	97.0	COG0633@1|root,COG0633@2|Bacteria,4NTCX@976|Bacteroidetes	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
HKD3_k127_2382565_2	1124780.ANNU01000013_gene3821	6.52e-128	416.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,4NE9M@976|Bacteroidetes,47P55@768503|Cytophagia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
HKD3_k127_2382565_7	1124780.ANNU01000013_gene3822	9.578e-08	55.0	COG5592@1|root,COG5592@2|Bacteria,4NP8M@976|Bacteroidetes,47S5H@768503|Cytophagia	976|Bacteroidetes	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_2389398_2	700598.Niako_6242	7.408e-179	570.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HKD3_k127_2389398_4	700598.Niako_6243	3.201e-52	188.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1IT21@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD3_k127_2389398_1	925409.KI911562_gene454	7.355e-198	619.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
HKD3_k127_2389398_3	1122605.KB893626_gene2749	4.449e-77	267.0	COG3757@1|root,COG3757@2|Bacteria,4NKHF@976|Bacteroidetes,1ISMY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl hydrolases family 25	acm	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
HKD3_k127_2389398_5	1288963.ADIS_2044	3.405e-13	79.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD3_k127_2389398_0	700598.Niako_6428	6.038e-199	625.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HKD3_k127_2397692_1	700598.Niako_1283	2.305e-05	53.0	2E82X@1|root,34BW2@2|Bacteria,4P6AY@976|Bacteroidetes,1IZ0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2397692_0	925409.KI911562_gene1013	3.719e-136	441.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1ISPB@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_2405050_0	1122605.KB893646_gene3	2.705e-18	96.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
HKD3_k127_2405050_1	1121481.AUAS01000007_gene1156	6.796e-11	73.0	COG5295@1|root,COG5295@2|Bacteria,4PPK6@976|Bacteroidetes	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_24248_7	1229487.AMYW01000021_gene1775	0.0001017	52.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia,2NSJZ@237|Flavobacterium	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_24248_4	1123248.KB893348_gene311	6.124e-81	279.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1IRJS@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HKD3_k127_24248_2	1123248.KB893348_gene312	2.997e-130	424.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD3_k127_24248_5	925409.KI911562_gene283	2.807e-60	218.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1IT51@117747|Sphingobacteriia	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_24248_3	1267211.KI669560_gene2548	3.652e-84	285.0	COG2859@1|root,COG2859@2|Bacteria,4NI76@976|Bacteroidetes,1IS8C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
HKD3_k127_24248_0	1250232.JQNJ01000001_gene1997	8.385e-163	524.0	COG2067@1|root,COG2067@2|Bacteria,4PFMQ@976|Bacteroidetes,1HYJE@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
HKD3_k127_24248_1	1304284.L21TH_2037	5.167e-161	522.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36DWE@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HKD3_k127_24248_6	471854.Dfer_5145	6.766e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,47JRE@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_2425602_1	1121957.ATVL01000009_gene1228	3.928e-63	228.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,4NHSQ@976|Bacteroidetes,47KNM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_2425602_0	1267211.KI669560_gene722	6.843e-189	593.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD3_k127_2425602_2	1267211.KI669560_gene721	9.15e-59	205.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,1ISNQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD3_k127_2455748_3	1122176.KB903531_gene2816	6.201e-21	110.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF285,DUF4988,DUF5122,FIVAR,YSIRK_signal
HKD3_k127_2455748_4	755732.Fluta_0604	2.87e-16	94.0	COG1357@1|root,COG3291@1|root,COG3405@1|root,COG4412@1|root,COG1357@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria,COG4412@2|Bacteria,4NMVW@976|Bacteroidetes,1I1JQ@117743|Flavobacteriia,2PBI2@246874|Cryomorphaceae	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
HKD3_k127_2455748_1	234267.Acid_4124	4.002e-63	248.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
HKD3_k127_2455748_2	1123248.KB893314_gene3656	1.872e-45	165.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1ITF1@117747|Sphingobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD3_k127_2455748_0	925409.KI911562_gene2316	5.803e-76	256.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD3_k127_2477626_1	1380600.AUYN01000001_gene2795	1.717e-35	141.0	COG1435@1|root,COG1435@2|Bacteria,4NE0S@976|Bacteroidetes,1I0FG@117743|Flavobacteriia	976|Bacteroidetes	F	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_2477626_0	1122179.KB890423_gene2345	4.669e-241	775.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IPHV@117747|Sphingobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_2512677_5	1500281.JQKZ01000009_gene3105	2.72e-05	48.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
HKD3_k127_2512677_0	485918.Cpin_4294	6.064e-72	249.0	COG2197@1|root,COG2197@2|Bacteria,4P2TZ@976|Bacteroidetes,1IXGA@117747|Sphingobacteriia	976|Bacteroidetes	K	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2512677_1	761193.Runsl_2864	2.441e-38	154.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,47PFT@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
HKD3_k127_2512677_3	1089547.KB913013_gene3633	3.538e-10	68.0	2E8V6@1|root,3335J@2|Bacteria,4NWZJ@976|Bacteroidetes,47S5R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2512677_4	485918.Cpin_2103	5.443e-10	70.0	COG2197@1|root,COG2197@2|Bacteria,4NT7P@976|Bacteroidetes	976|Bacteroidetes	K	Psort location Cytoplasmic, score 9.97	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2512677_2	926562.Oweho_1851	2.873e-20	95.0	COG3420@1|root,COG3420@2|Bacteria,4PPAE@976|Bacteroidetes,1IKH4@117743|Flavobacteriia,2PBVP@246874|Cryomorphaceae	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_253122_4	700598.Niako_6652	1.716e-08	58.0	2DQSK@1|root,338E4@2|Bacteria,4NX60@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_253122_3	1123248.KB893314_gene3615	1.799e-20	94.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU2I@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HKD3_k127_253122_0	929713.NIASO_11525	1.788e-244	758.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1IP9V@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HKD3_k127_253122_1	1123248.KB893314_gene3613	2.75e-110	366.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1IQ87@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1131 ABC-type multidrug transport system ATPase component	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_253122_2	991.IW20_15310	1.661e-29	123.0	COG2067@1|root,COG2067@2|Bacteria,4NGWZ@976|Bacteroidetes,1IJ7F@117743|Flavobacteriia,2NUCT@237|Flavobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_2539042_0	1122605.KB893646_gene110	1.923e-208	651.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD3_k127_2539042_2	925409.KI911562_gene444	3.923e-130	426.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IPFH@117747|Sphingobacteriia	976|Bacteroidetes	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
HKD3_k127_2539042_7	234267.Acid_5965	1.152e-59	235.0	COG2374@1|root,COG3386@1|root,COG2374@2|Bacteria,COG3386@2|Bacteria,3Y6HZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF1573,Exo_endo_phos,LTD
HKD3_k127_2539042_4	491205.JARQ01000003_gene2067	2.69e-76	287.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia,3ZNZ0@59732|Chryseobacterium	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Endonuclease_1,LTD,fn3
HKD3_k127_2539042_1	1123248.KB893348_gene233	1.668e-196	619.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_2539042_3	1122605.KB893625_gene2099	1.321e-120	394.0	COG3266@1|root,COG3266@2|Bacteria,4NFRK@976|Bacteroidetes,1IUYF@117747|Sphingobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2539042_6	1185876.BN8_01157	4.966e-62	222.0	COG0726@1|root,COG0726@2|Bacteria,4NGMX@976|Bacteroidetes,47M1V@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_2539042_5	1267211.KI669560_gene58	4.922e-62	222.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,1IT4J@117747|Sphingobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD3_k127_2539042_8	468059.AUHA01000007_gene2695	7.121e-48	175.0	2CEQ4@1|root,2ZUK4@2|Bacteria,4NPFT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2559530_0	1089547.KB913013_gene3764	1.523e-214	681.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47JYM@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
HKD3_k127_2559530_1	1123277.KB893198_gene6327	7.509e-72	259.0	COG0845@1|root,COG0845@2|Bacteria,4P48K@976|Bacteroidetes,47PIQ@768503|Cytophagia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HKD3_k127_2572739_0	700598.Niako_2576	1.835e-213	673.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1INQK@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	aldH	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD3_k127_2572739_1	485918.Cpin_5586	5.267e-132	427.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1IQRX@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_2572739_2	471854.Dfer_4283	2.322e-72	254.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NGHV@976|Bacteroidetes,47PQJ@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
HKD3_k127_2572739_4	391598.FBBAL38_09679	2.461e-05	49.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
HKD3_k127_2572739_3	1380394.JADL01000003_gene4962	8.707e-08	60.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
HKD3_k127_2578982_2	925409.KI911562_gene3007	6.357e-81	274.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1IPJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD3_k127_2578982_4	1358423.N180_16155	4.453e-29	119.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1IY6M@117747|Sphingobacteriia	976|Bacteroidetes	S	RNA polymerase Rpb6	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
HKD3_k127_2578982_1	925409.KI911562_gene3009	2.144e-87	296.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
HKD3_k127_2578982_0	700598.Niako_5113	6.128e-93	312.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD3_k127_2578982_3	485918.Cpin_6987	3.021e-45	176.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD3_k127_2578982_5	1122605.KB893644_gene1524	8.15e-16	78.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_2602694_5	929703.KE386491_gene2389	1.401e-14	72.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_2602694_1	700598.Niako_7044	2.09e-80	275.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,1IQTT@117747|Sphingobacteriia	976|Bacteroidetes	J	Pseudouridine synthase	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HKD3_k127_2602694_0	925409.KI911562_gene1549	2.462e-90	303.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1IPUQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD3_k127_2602694_4	1123248.KB893355_gene4711	1.892e-23	114.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K02487,ko:K13582	ko02020,ko04112,map02020,map04112	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	DUF4157,DUF4476,NLPC_P60,PG_binding_1,Sel1
HKD3_k127_2602694_2	1279009.ADICEAN_00868	7.512e-33	131.0	COG0824@1|root,COG0824@2|Bacteria,4NSIG@976|Bacteroidetes,47S22@768503|Cytophagia	976|Bacteroidetes	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
HKD3_k127_2602694_3	1237149.C900_02493	2.162e-26	111.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
HKD3_k127_2609272_3	1123248.KB893348_gene352	1.33e-56	209.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
HKD3_k127_2609272_1	1267211.KI669560_gene1358	1.429e-72	248.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1ISTD@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HKD3_k127_2609272_2	1123248.KB893348_gene350	4.681e-71	252.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1IP5H@117747|Sphingobacteriia	976|Bacteroidetes	NU	COG1705 Muramidase (flagellum-specific)	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
HKD3_k127_2609272_0	925409.KI911562_gene90	3.939e-75	258.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_2614505_3	929703.KE386491_gene100	3.745e-28	115.0	2E6C9@1|root,33102@2|Bacteria,4NVI3@976|Bacteroidetes,47T33@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2614505_1	1279009.ADICEAN_02104	2.137e-67	237.0	COG5395@1|root,COG5395@2|Bacteria,4NSVW@976|Bacteroidetes,47XVK@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
HKD3_k127_2614505_0	1122176.KB903532_gene2532	1.743e-148	486.0	COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1IV5V@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HKD3_k127_2614505_4	616991.JPOO01000003_gene2303	1.316e-07	53.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1HY7B@117743|Flavobacteriia,23GGB@178469|Arenibacter	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
HKD3_k127_2617535_4	938709.AUSH02000073_gene1679	1.235e-22	98.0	COG1914@1|root,COG1914@2|Bacteria,4NDZ1@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_2617535_2	929562.Emtol_0895	5.364e-45	167.0	COG0454@1|root,COG0456@2|Bacteria,4NPGI@976|Bacteroidetes,47R57@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	yjaB	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
HKD3_k127_2617535_3	742767.HMPREF9456_03071	8.086e-40	158.0	COG2207@1|root,COG2207@2|Bacteria,4NM90@976|Bacteroidetes,2FUB1@200643|Bacteroidia,22XVC@171551|Porphyromonadaceae	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02508	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
HKD3_k127_2617535_1	1120968.AUBX01000010_gene1204	1.183e-119	390.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47Q3U@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
HKD3_k127_2617535_0	925409.KI911562_gene1461	1.556e-126	407.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
HKD3_k127_2623219_1	1120965.AUBV01000009_gene2971	4.466e-56	218.0	COG0457@1|root,COG0457@2|Bacteria,4NKED@976|Bacteroidetes,47N3J@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_2623219_0	929713.NIASO_05165	6.025e-248	803.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IPF5@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
HKD3_k127_2626256_0	700598.Niako_5795	2.982e-144	461.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
HKD3_k127_2626256_4	984262.SGRA_2566	1.161e-07	53.0	2DTGS@1|root,33K9M@2|Bacteria,4NYMF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2626256_2	1123248.KB893386_gene1838	7.029e-62	223.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HKD3_k127_2626256_3	1123248.KB893386_gene1839	6.72e-49	175.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1ISXQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_2626256_1	700598.Niako_5791	2.954e-106	353.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1IPZD@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
HKD3_k127_2626270_0	925409.KI911562_gene582	1.365e-143	458.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD3_k127_2626270_3	1123248.KB893348_gene212	1.423e-104	348.0	COG3637@1|root,COG3637@2|Bacteria,4NNPF@976|Bacteroidetes,1ISTC@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_2626270_2	1267211.KI669560_gene284	1.34e-123	402.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HKD3_k127_2626270_4	925409.KI911562_gene897	4.163e-104	355.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,1IWQ4@117747|Sphingobacteriia	976|Bacteroidetes	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD3_k127_2626270_7	1123248.KB893348_gene209	2.582e-53	196.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1IRUD@117747|Sphingobacteriia	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_2626270_1	925409.KI911562_gene895	1.733e-141	451.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1INU7@117747|Sphingobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD3_k127_2626270_9	700598.Niako_6587	4.068e-41	158.0	COG1286@1|root,COG1286@2|Bacteria,4P9DM@976|Bacteroidetes,1IZI5@117747|Sphingobacteriia	976|Bacteroidetes	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
HKD3_k127_2626270_6	700598.Niako_6586	3.387e-54	194.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1IT3W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HKD3_k127_2626270_8	925409.KI911562_gene892	4.036e-44	162.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1ISTG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein, GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2626270_12	925409.KI911562_gene891	2.215e-20	103.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1ITGA@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_2626270_5	1267211.KI669560_gene309	3.125e-82	280.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1IQZH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
HKD3_k127_2626270_10	880071.Fleli_0042	1.068e-40	158.0	COG2340@1|root,COG2340@2|Bacteria,4NW16@976|Bacteroidetes,47SFM@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
HKD3_k127_2626270_11	1123276.KB893312_gene3006	2.866e-33	136.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2676256_4	700598.Niako_5697	4.395e-19	86.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,1ISXM@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_2676256_2	313598.MED152_01475	1.181e-57	225.0	COG4249@1|root,COG4249@2|Bacteria,4NSC3@976|Bacteroidetes,1I5UC@117743|Flavobacteriia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_2
HKD3_k127_2676256_3	113355.CM001775_gene2675	6.181e-32	144.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	113355.CM001775_gene2675|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2676256_1	1121904.ARBP01000002_gene7106	1.447e-75	271.0	COG4870@1|root,COG4870@2|Bacteria,4NGK1@976|Bacteroidetes,47MRK@768503|Cytophagia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C1
HKD3_k127_2676256_0	925409.KI911562_gene1454	1.566e-144	473.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_2676256_5	1121373.KB903662_gene254	8.05e-09	65.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,He_PIG,SprB
HKD3_k127_2686651_2	700598.Niako_6365	7.037e-72	259.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,1IPER@117747|Sphingobacteriia	976|Bacteroidetes	S	FUSC-like inner membrane protein yccS	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
HKD3_k127_2686651_0	468059.AUHA01000002_gene747	8.864e-95	317.0	COG3662@1|root,COG3662@2|Bacteria,4NEYP@976|Bacteroidetes,1IPRC@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
HKD3_k127_2686651_1	643867.Ftrac_2752	2.868e-85	289.0	COG5434@1|root,COG5434@2|Bacteria,4NFZJ@976|Bacteroidetes,47K9P@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,fn3
HKD3_k127_2706572_2	925409.KI911562_gene882	2.455e-58	211.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1IS0E@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
HKD3_k127_2706572_3	1267211.KI669560_gene697	2.301e-46	170.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1ISS0@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HKD3_k127_2706572_0	1123248.KB893319_gene4072	0.0	1015.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IQ2Z@117747|Sphingobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD3_k127_2706572_1	925409.KI911562_gene885	3.268e-70	243.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1IRJ2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
HKD3_k127_2706572_4	1267211.KI669560_gene700	2.067e-37	144.0	COG2105@1|root,COG2105@2|Bacteria	2|Bacteria	F	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
HKD3_k127_2716638_0	700598.Niako_0114	3.26e-177	565.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
HKD3_k127_2716638_1	743722.Sph21_3224	0.000539	43.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1IRCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
HKD3_k127_2724976_0	1267211.KI669560_gene1380	5.423e-159	503.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD3_k127_2724976_1	700598.Niako_4661	1.217e-158	509.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1IP0F@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD3_k127_2724976_2	714943.Mucpa_4311	2.651e-101	337.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1IQME@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_2724976_3	926549.KI421517_gene2103	2.309e-89	304.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,47NHD@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
HKD3_k127_2748530_2	925409.KI911562_gene63	4.063e-143	459.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_2748530_4	700598.Niako_0289	1.702e-25	111.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1ITEJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_2748530_5	1150600.ADIARSV_2331	2.557e-22	102.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1J0JC@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_2748530_1	1408473.JHXO01000011_gene3168	1.272e-149	491.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,2FUDK@200643|Bacteroidia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
HKD3_k127_2748530_0	1267211.KI669560_gene2552	1.159e-225	704.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_2748530_3	391587.KAOT1_20322	1.11e-48	182.0	COG0500@1|root,COG2226@2|Bacteria,4PKP0@976|Bacteroidetes,1IJW3@117743|Flavobacteriia	976|Bacteroidetes	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD3_k127_2748530_6	858215.Thexy_2218	1.603e-06	56.0	COG2273@1|root,COG5492@1|root,COG2273@2|Bacteria,COG5492@2|Bacteria,1UIAA@1239|Firmicutes,25EFC@186801|Clostridia,42H7E@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM S-layer	-	-	3.2.1.82	ko:K18650	-	-	-	-	ko00000,ko01000	-	GH28	-	Big_5,SLH
HKD3_k127_2770452_0	1463825.JNXC01000033_gene1651	9.274e-118	394.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria,4DX5S@85010|Pseudonocardiales	201174|Actinobacteria	Q	Retinal pigment epithelial membrane protein	-	-	1.13.11.75	ko:K00464,ko:K11159	-	-	R09601	RC00912	ko00000,ko01000	-	-	-	RPE65
HKD3_k127_27734_0	1122605.KB893643_gene602	6.327e-158	499.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD3_k127_2777599_0	1123248.KB893318_gene4172	5.497e-180	567.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
HKD3_k127_2777599_2	762903.Pedsa_0927	1.887e-41	156.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
HKD3_k127_2777599_1	925409.KI911562_gene2510	1.023e-69	237.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
HKD3_k127_2779523_0	700598.Niako_1939	9.992e-209	664.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_2779523_3	485918.Cpin_0678	2.184e-81	277.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_2779523_2	925409.KI911562_gene187	8.181e-94	317.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1INKY@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD3_k127_2779523_1	1267211.KI669560_gene2098	2.528e-106	350.0	COG3268@1|root,COG3268@2|Bacteria,4NHDM@976|Bacteroidetes,1IRKS@117747|Sphingobacteriia	976|Bacteroidetes	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
HKD3_k127_2822220_2	1123035.ARLA01000027_gene392	4.198e-19	89.0	COG2956@1|root,COG2956@2|Bacteria,4PI3R@976|Bacteroidetes,1ICAR@117743|Flavobacteriia,4C4A6@83612|Psychroflexus	976|Bacteroidetes	G	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
HKD3_k127_2822220_0	1392488.JHZY01000004_gene1918	2.688e-118	387.0	COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1HZT9@117743|Flavobacteriia	976|Bacteroidetes	P	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
HKD3_k127_2829092_0	925409.KI911562_gene2260	5.143e-107	355.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD3_k127_2829092_1	468059.AUHA01000003_gene2006	2.055e-104	347.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,1IQ4K@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
HKD3_k127_2842181_2	925409.KI911562_gene94	1.184e-87	292.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
HKD3_k127_2842181_3	1267211.KI669560_gene1206	9.584e-83	278.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1IRY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HKD3_k127_2842181_1	1123248.KB893359_gene2117	5.783e-114	371.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_2842181_5	485918.Cpin_6887	4.211e-21	96.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1ITUB@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HKD3_k127_2842181_0	1453498.LG45_15465	7.681e-125	407.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,1HYW6@117743|Flavobacteriia,2NUG8@237|Flavobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_2842181_4	869213.JCM21142_31167	7.842e-27	113.0	COG0366@1|root,COG0366@2|Bacteria,4PIQV@976|Bacteroidetes,47TNQ@768503|Cytophagia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
HKD3_k127_2848304_1	1185876.BN8_00896	4.53e-99	334.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_2848304_2	886377.Murru_1270	1.363e-93	308.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,1HYIR@117743|Flavobacteriia	976|Bacteroidetes	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD3_k127_2848304_4	641524.ADICYQ_2800	1.897e-15	76.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,47N33@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD3_k127_2848304_0	714943.Mucpa_2158	5.76e-109	371.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IR03@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HKD3_k127_2848304_3	1122605.KB893637_gene3054	9.561e-27	113.0	COG1819@1|root,COG1819@2|Bacteria,4NIX4@976|Bacteroidetes,1IWR9@117747|Sphingobacteriia	976|Bacteroidetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
HKD3_k127_2872777_2	1279009.ADICEAN_00317	6.159e-68	235.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,47MB5@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
HKD3_k127_2872777_1	925409.KI911562_gene1785	3.07e-142	455.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1INN5@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
HKD3_k127_2872777_3	485918.Cpin_2572	4.625e-12	66.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD3_k127_2872777_0	1123248.KB893340_gene2670	4.119e-173	550.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1INY0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_2888247_0	1267211.KI669560_gene2060	1.374e-173	554.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IV0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
HKD3_k127_2888247_1	925409.KI911562_gene2277	7.783e-27	109.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_2889748_1	1267211.KI669560_gene385	1.989e-102	341.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1IS2B@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_2889748_2	925409.KI911562_gene624	6.452e-91	307.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1IS1R@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
HKD3_k127_2889748_0	700598.Niako_6071	6.818e-199	633.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1IQPD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD3_k127_2889748_4	1122973.KB904283_gene1000	3.24e-43	164.0	2DM5T@1|root,31U0Y@2|Bacteria,4NMMA@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
HKD3_k127_2889748_5	700598.Niako_6384	1.726e-38	145.0	COG3369@1|root,COG3369@2|Bacteria,4NSK8@976|Bacteroidetes,1IYRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
HKD3_k127_2889748_3	700598.Niako_3423	1.641e-44	173.0	COG3897@1|root,COG3897@2|Bacteria,4P696@976|Bacteroidetes,1IZ1E@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
HKD3_k127_291967_2	700598.Niako_6638	2.581e-85	297.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1INKX@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD3_k127_291967_1	1434325.AZQN01000004_gene1778	1.783e-127	416.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,47JBH@768503|Cytophagia	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
HKD3_k127_291967_0	925409.KI911562_gene1820	6.251e-150	484.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,4NGF6@976|Bacteroidetes,1IQ4D@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	nhaA	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
HKD3_k127_2928072_8	1267211.KI669560_gene1511	4.464e-45	168.0	28N01@1|root,2ZB6M@2|Bacteria,4NFN1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2928072_3	700598.Niako_0099	4.033e-201	638.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1IQVW@117747|Sphingobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2928072_4	925409.KI911562_gene559	4.864e-200	628.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,1INXS@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
HKD3_k127_2928072_1	925409.KI911562_gene558	9.607e-244	759.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1INV1@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
HKD3_k127_2928072_7	485918.Cpin_1984	6.061e-81	274.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1IQ0S@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HKD3_k127_2928072_5	700598.Niako_0101	2.569e-174	553.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1INYR@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_2928072_6	468059.AUHA01000004_gene2076	1.674e-107	357.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1IPAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_2928072_0	1338011.BD94_3411	5.365e-300	926.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia,34PMN@308865|Elizabethkingia	976|Bacteroidetes	E	Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HKD3_k127_2928072_2	743722.Sph21_2289	1.264e-225	706.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1IPTP@117747|Sphingobacteriia	976|Bacteroidetes	EH	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD3_k127_2989471_4	1434325.AZQN01000008_gene2924	1.152e-59	211.0	COG0662@1|root,COG0662@2|Bacteria,4NNWT@976|Bacteroidetes,47Q0Y@768503|Cytophagia	976|Bacteroidetes	G	PFAM Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
HKD3_k127_2989471_3	485918.Cpin_0792	8.169e-73	259.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1IU84@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_2989471_0	1267211.KI669560_gene2525	8.695e-203	640.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HKD3_k127_2989471_5	880070.Cycma_3309	2.864e-58	211.0	COG2135@1|root,COG2135@2|Bacteria,4NKPN@976|Bacteroidetes,47MR7@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HKD3_k127_2989471_1	925409.KI911562_gene21	1.316e-84	286.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HKD3_k127_2989471_6	925409.KI911562_gene20	6.863e-51	184.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,1IT0H@117747|Sphingobacteriia	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HKD3_k127_2989471_2	1123248.KB893314_gene3434	1.565e-77	268.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,1IQMF@117747|Sphingobacteriia	976|Bacteroidetes	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
HKD3_k127_2989471_7	1237149.C900_02493	2.247e-43	164.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
HKD3_k127_3000762_1	700598.Niako_6884	1.054e-74	254.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_3000762_0	1122605.KB893628_gene4483	1.356e-113	387.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,1IPR3@117747|Sphingobacteriia	976|Bacteroidetes	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD3_k127_3000762_2	700598.Niako_6887	3.797e-50	179.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HKD3_k127_30096_3	1123248.KB893314_gene3600	7.006e-48	176.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_30096_2	1123248.KB893314_gene3601	1.868e-78	272.0	COG0605@1|root,COG0605@2|Bacteria,4NK61@976|Bacteroidetes,1IRYF@117747|Sphingobacteriia	976|Bacteroidetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD3_k127_30096_4	925409.KI911562_gene235	5.552e-35	138.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
HKD3_k127_30096_0	1267211.KI669560_gene926	3.612e-122	400.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1IP0G@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD3_k127_30096_1	1123248.KB893331_gene3793	2.1e-86	291.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1IXCK@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD3_k127_30096_5	925409.KI911562_gene46	4.993e-29	122.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
HKD3_k127_3071833_0	925409.KI911562_gene826	1.708e-80	271.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1INZJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HKD3_k127_3071833_1	1121957.ATVL01000009_gene1383	1.238e-42	162.0	COG0454@1|root,COG0456@2|Bacteria,4NQSN@976|Bacteroidetes,47Q25@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_3071833_2	700598.Niako_6274	1.271e-05	48.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD3_k127_308423_1	1267211.KI669560_gene1252	5.144e-155	494.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Glycoamylase
HKD3_k127_308423_0	1122605.KB893626_gene2437	2.121e-222	695.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IQRK@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
HKD3_k127_31307_3	925409.KI911562_gene2282	2.005e-21	96.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
HKD3_k127_31307_1	925409.KI911562_gene2284	8.102e-68	234.0	COG1666@1|root,COG1666@2|Bacteria,4NMBZ@976|Bacteroidetes,1IRSS@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
HKD3_k127_31307_2	485918.Cpin_6211	9.54e-40	149.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ITGS@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HKD3_k127_31307_0	1123248.KB893323_gene1574	1.339e-101	344.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1IP3D@117747|Sphingobacteriia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
HKD3_k127_31307_4	700598.Niako_2168	4.554e-06	52.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1IPGF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HKD3_k127_3161946_6	555779.Dthio_PD1962	0.0002488	47.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD3_k127_3161946_5	1174504.AJTN02000120_gene4835	1.55e-07	57.0	2BR4S@1|root,32K2S@2|Bacteria,1U1SU@1239|Firmicutes,4IB95@91061|Bacilli,1ZKR2@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3161946_3	760192.Halhy_5034	1.261e-24	108.0	2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_3161946_1	1267211.KI669560_gene266	5.142e-128	426.0	COG1807@1|root,COG1807@2|Bacteria,4NKI5@976|Bacteroidetes,1J09F@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_3161946_2	700598.Niako_5494	1.691e-114	378.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_3161946_0	700598.Niako_4480	6.289e-212	689.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_3161946_4	1123248.KB893318_gene4168	2.18e-15	78.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_3194609_4	1122621.ATZA01000012_gene3081	5.816e-14	78.0	COG3528@1|root,COG3528@2|Bacteria,4NN7J@976|Bacteroidetes,1IS3K@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
HKD3_k127_3194609_0	504472.Slin_5068	1.055e-141	465.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,47JWZ@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
HKD3_k127_3194609_1	1267211.KI669560_gene543	8.777e-115	374.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IXQH@117747|Sphingobacteriia	976|Bacteroidetes	M	Cytidylyltransferase	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
HKD3_k127_3194609_3	1338011.BD94_2447	2.903e-22	104.0	COG0664@1|root,COG0664@2|Bacteria,4NF0T@976|Bacteroidetes,1I7QR@117743|Flavobacteriia,34RTN@308865|Elizabethkingia	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_3194609_2	649638.Trad_0672	1.308e-53	192.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,GARS_A,Glu_cys_ligase
HKD3_k127_3194667_6	1086011.HJ01_01152	6.731e-22	102.0	COG3528@1|root,COG3528@2|Bacteria,4NHTR@976|Bacteroidetes,1HZ67@117743|Flavobacteriia,2NZW4@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
HKD3_k127_3194667_3	1123248.KB893319_gene4034	1.195e-38	149.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1ITI6@117747|Sphingobacteriia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HKD3_k127_3194667_0	700598.Niako_6359	1.814e-196	616.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HKD3_k127_3194667_1	1122605.KB893626_gene2383	2.233e-101	337.0	COG3000@1|root,COG3000@2|Bacteria,4NI62@976|Bacteroidetes	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_3194667_5	700598.Niako_4519	1.232e-28	121.0	2EDN0@1|root,337HT@2|Bacteria,4NVQJ@976|Bacteroidetes,1ITXS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3194667_2	700598.Niako_4518	4.09e-68	236.0	COG1595@1|root,COG1595@2|Bacteria,4NP02@976|Bacteroidetes,1J06I@117747|Sphingobacteriia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_3194667_4	700598.Niako_4517	2.728e-32	130.0	2EFPT@1|root,339FT@2|Bacteria,4NV1V@976|Bacteroidetes,1IU65@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_31970_0	700598.Niako_5689	2.827e-215	672.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD3_k127_31970_4	1123248.KB893386_gene1821	3.016e-28	118.0	COG0662@1|root,COG0662@2|Bacteria,4NVRF@976|Bacteroidetes,1ITU1@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_31970_3	925409.KI911562_gene428	2.382e-136	441.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1IPHE@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_31970_1	1267211.KI669560_gene78	2.891e-207	649.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1IQUC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_31970_2	700598.Niako_5692	2.187e-140	449.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1IQ2H@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD3_k127_3200586_2	468059.AUHA01000002_gene1349	7.978e-86	298.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1INYY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,Sulfate_transp
HKD3_k127_3200586_1	929556.Solca_1743	2.33e-168	535.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1IPKV@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD3_k127_3200586_0	1267211.KI669560_gene2086	6.264e-198	623.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HKD3_k127_3208784_0	925409.KI911562_gene1201	6.983e-301	927.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD3_k127_3208784_1	522306.CAP2UW1_2764	3.274e-123	403.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria	1224|Proteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
HKD3_k127_3208784_2	1173264.KI913949_gene456	1.725e-15	85.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria,1HC1X@1150|Oscillatoriales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_3208958_1	1122223.KB890696_gene75	1.888e-13	71.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
HKD3_k127_3208958_0	925409.KI911562_gene1119	5.948e-119	398.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,1IRQU@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_3231267_1	1034807.FBFL15_0028	7.831e-36	143.0	2A2MK@1|root,30QZX@2|Bacteria,4P5NJ@976|Bacteroidetes,1IDRG@117743|Flavobacteriia,2NZ12@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3231267_0	1227739.Hsw_2715	3.409e-62	219.0	COG0386@1|root,COG0386@2|Bacteria,4NP8C@976|Bacteroidetes,47Q5J@768503|Cytophagia	976|Bacteroidetes	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD3_k127_3231267_2	1379270.AUXF01000002_gene1604	2.328e-13	72.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
HKD3_k127_3234580_1	1239962.C943_03737	1.8e-101	337.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_3234580_2	1089551.KE386572_gene380	0.0001373	48.0	2AD0I@1|root,33I70@2|Bacteria,1NPNH@1224|Proteobacteria,2UMCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3234580_0	1239962.C943_03733	4.738e-139	458.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4P3P6@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3238721_4	1123248.KB893334_gene2742	3.632e-20	90.0	COG3646@1|root,COG3646@2|Bacteria,4NR28@976|Bacteroidetes,1IVCU@117747|Sphingobacteriia	976|Bacteroidetes	L	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
HKD3_k127_3238721_1	700598.Niako_5693	2.718e-96	322.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1IPBE@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_3238721_2	1500281.JQKZ01000016_gene522	4.646e-49	182.0	COG0637@1|root,COG0637@2|Bacteria,4NID6@976|Bacteroidetes,1IGER@117743|Flavobacteriia,3ZSQM@59732|Chryseobacterium	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD3_k127_3238721_0	1122605.KB893626_gene2647	4.839e-159	507.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_3238721_3	700598.Niako_5695	1.298e-38	146.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
HKD3_k127_3247153_3	1121957.ATVL01000008_gene4603	8.369e-08	57.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD3_k127_3247153_2	382245.ASA_0853	6.241e-25	109.0	COG3187@1|root,COG3187@2|Bacteria,1Q120@1224|Proteobacteria,1SVU8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3247153_0	929713.NIASO_05335	2.388e-246	781.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
HKD3_k127_3247153_4	700598.Niako_1374	1.454e-07	56.0	2BVY1@1|root,32QYH@2|Bacteria,4NR2M@976|Bacteroidetes,1IU20@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3247153_1	1121904.ARBP01000005_gene4823	2.018e-34	134.0	28MAS@1|root,2ZAPE@2|Bacteria,4NJ31@976|Bacteroidetes,47TP8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
HKD3_k127_3247625_1	926569.ANT_02970	4.297e-110	361.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
HKD3_k127_3247625_0	926569.ANT_02950	4.534e-202	635.0	COG0402@1|root,COG0402@2|Bacteria,2G6K7@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
HKD3_k127_3247625_2	926569.ANT_05790	1.083e-62	218.0	COG1529@1|root,COG1529@2|Bacteria,2G7M5@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HKD3_k127_3266936_4	485918.Cpin_7085	1.022e-13	73.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_3266936_3	925409.KI911562_gene277	8.219e-110	362.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_3266936_0	700598.Niako_5629	2.874e-285	879.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1IPCY@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD3_k127_3266936_1	925409.KI911562_gene1176	3.401e-211	673.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD3_k127_3266936_2	1123057.P872_02235	2.955e-154	496.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3281783_0	866536.Belba_1327	6.69e-112	369.0	COG1819@1|root,COG1819@2|Bacteria,4NHMR@976|Bacteroidetes	976|Bacteroidetes	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
HKD3_k127_3281783_5	1337936.IJ00_08165	1.228e-13	76.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,1HMT6@1161|Nostocales	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
HKD3_k127_3281783_3	760192.Halhy_0964	1.962e-74	258.0	28PP7@1|root,2ZCBP@2|Bacteria,4NMEU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3281783_1	929703.KE386491_gene1065	2.803e-96	321.0	COG0491@1|root,COG0491@2|Bacteria,4NPPW@976|Bacteroidetes,47MDW@768503|Cytophagia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	ccrA	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HKD3_k127_3281783_4	929562.Emtol_2272	6.857e-71	244.0	COG0664@1|root,COG0664@2|Bacteria,4NJRX@976|Bacteroidetes,47QTJ@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_3281783_2	1168034.FH5T_18105	3.548e-87	296.0	COG3403@1|root,COG3403@2|Bacteria,4NHNG@976|Bacteroidetes	976|Bacteroidetes	S	YqcI/YcgG family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_331101_0	925409.KI911562_gene2360	3.803e-229	718.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1IQ2K@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
HKD3_k127_331101_3	1123248.KB893314_gene3652	3.58e-37	145.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1IU5B@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HKD3_k127_331101_4	1450525.JATV01000013_gene2867	9.363e-32	133.0	COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,1I1IJ@117743|Flavobacteriia,2NTQM@237|Flavobacterium	976|Bacteroidetes	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
HKD3_k127_331101_2	1267211.KI669560_gene1834	8.578e-68	236.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS7R@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HKD3_k127_331101_1	925409.KI911562_gene2490	5.927e-86	295.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IQZY@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HKD3_k127_331101_7	1123248.KB893326_gene1425	1.252e-12	69.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1IQTV@117747|Sphingobacteriia	976|Bacteroidetes	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD3_k127_3323755_4	1210884.HG799462_gene8899	1.594e-08	62.0	COG2382@1|root,COG2382@2|Bacteria,2J2KX@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_3323755_1	1189612.A33Q_1403	1.586e-79	280.0	COG5504@1|root,COG5504@2|Bacteria,4NJ10@976|Bacteroidetes,47QY0@768503|Cytophagia	976|Bacteroidetes	O	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2268
HKD3_k127_3323755_2	700598.Niako_2721	1.782e-79	275.0	COG0392@1|root,COG0392@2|Bacteria,4NMZ1@976|Bacteroidetes,1IRX8@117747|Sphingobacteriia	976|Bacteroidetes	O	Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_3323755_0	1150600.ADIARSV_3918	1.692e-146	469.0	COG1216@1|root,COG1216@2|Bacteria,4NGEQ@976|Bacteroidetes,1IPXG@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_3323755_3	925409.KI911562_gene1521	1.995e-21	94.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HKD3_k127_3347840_0	925409.KI911562_gene2121	3.14e-154	489.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1IQC9@117747|Sphingobacteriia	976|Bacteroidetes	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HKD3_k127_3347840_2	1341181.FLJC2902T_00880	9.906e-55	201.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes,1IAW1@117743|Flavobacteriia,2NWKD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3347840_1	1122605.KB893625_gene2294	1.111e-118	384.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1IRAS@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HKD3_k127_336425_1	1123248.KB893386_gene1870	1.727e-66	229.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,1INSK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
HKD3_k127_336425_4	743722.Sph21_2982	3.662e-09	60.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes,1IU7C@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_336425_0	1267211.KI669560_gene2369	1.043e-261	812.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD3_k127_3368933_2	1121904.ARBP01000005_gene4662	8.449e-58	204.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM GTP cyclohydrolase I	-	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD3_k127_3368933_0	929713.NIASO_19240	4.942e-63	218.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes	976|Bacteroidetes	H	Pfam 6-pyruvoyl tetrahydropterin synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD3_k127_3368933_1	929713.NIASO_19245	5.118e-63	218.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1ISCG@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydrobiopterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD3_k127_3368933_3	313606.M23134_08367	1.236e-20	92.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
HKD3_k127_3400861_0	1123248.KB893359_gene2069	3.978e-136	449.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
HKD3_k127_3400861_2	1123248.KB893359_gene2070	5.054e-52	189.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,1IT8Z@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
HKD3_k127_3400861_1	925409.KI911562_gene1822	9.18e-103	338.0	COG1428@1|root,COG1428@2|Bacteria,4PM5R@976|Bacteroidetes,1IXF2@117747|Sphingobacteriia	976|Bacteroidetes	F	Thymidylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD3_k127_3400861_3	925409.KI911562_gene1570	1.493e-25	108.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_341500_2	1123248.KB893323_gene1643	1.98e-74	254.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes	976|Bacteroidetes	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HKD3_k127_341500_0	925409.KI911562_gene2161	9.645e-267	824.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1IQTE@117747|Sphingobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
HKD3_k127_341500_1	700598.Niako_1885	2.057e-102	338.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1IPKD@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD3_k127_341500_3	1227739.Hsw_1926	2.502e-44	164.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,47NIJ@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD3_k127_3445667_0	760192.Halhy_2511	5.316e-122	399.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,1IWZS@117747|Sphingobacteriia	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
HKD3_k127_3445667_1	700598.Niako_1172	1.799e-20	94.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA,TonB_dep_Rec
HKD3_k127_3445667_2	319236.JCM19294_2560	1.824e-06	57.0	COG5608@1|root,COG5608@2|Bacteria,4NVQ5@976|Bacteroidetes,1IE5G@117743|Flavobacteriia,3HKIM@363408|Nonlabens	976|Bacteroidetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
HKD3_k127_3467470_2	1267211.KI669560_gene1609	1.546e-14	79.0	2EUHG@1|root,33MZM@2|Bacteria,4NZ9U@976|Bacteroidetes,1IZZA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3467470_1	762903.Pedsa_2028	9.932e-31	136.0	COG2207@1|root,COG2207@2|Bacteria,4NTZ2@976|Bacteroidetes,1IXMS@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_3467470_0	1120968.AUBX01000012_gene2681	6.267e-208	651.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,47JCN@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
HKD3_k127_3519968_0	1123248.KB893317_gene4410	1.024e-90	307.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,1INZY@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_3519968_1	700598.Niako_2912	1.855e-78	270.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
HKD3_k127_3519968_3	886377.Murru_2920	8.215e-20	92.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD3_k127_3519968_2	700598.Niako_2926	5.596e-57	204.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HKD3_k127_352620_3	762903.Pedsa_0401	2.081e-47	177.0	COG2246@1|root,COG2246@2|Bacteria,4NSQN@976|Bacteroidetes,1ITAX@117747|Sphingobacteriia	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HKD3_k127_352620_0	1123248.KB893330_gene416	4.798e-252	791.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HKD3_k127_352620_1	1123248.KB893320_gene3844	5.018e-223	724.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1IQ3X@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD3_k127_352620_2	1123248.KB893381_gene1093	1.399e-59	214.0	28NAE@1|root,2ZBE7@2|Bacteria,4NJNX@976|Bacteroidetes,1IS37@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_352620_4	1094466.KQS_01100	7.452e-37	143.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia,2NT7V@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208,ko:K21575	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
HKD3_k127_3580104_5	1123248.KB893319_gene4022	9.081e-40	152.0	COG1807@1|root,COG1807@2|Bacteria,4NHXW@976|Bacteroidetes,1IR5R@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_3580104_6	1408473.JHXO01000006_gene1325	1.054e-24	104.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,2FYPS@200643|Bacteroidia	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD3_k127_3580104_1	1123234.AUKI01000017_gene2508	1.819e-108	360.0	COG0667@1|root,COG0667@2|Bacteria,4NF06@976|Bacteroidetes,1HZ2C@117743|Flavobacteriia	976|Bacteroidetes	C	Aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_3580104_2	714943.Mucpa_3925	2.971e-70	240.0	COG2185@1|root,COG2185@2|Bacteria,4NNXP@976|Bacteroidetes,1ISIG@117747|Sphingobacteriia	976|Bacteroidetes	I	COGs COG2185 Methylmalonyl-CoA mutase C-terminal domain subunit (cobalamin-binding)	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
HKD3_k127_3580104_4	929556.Solca_1396	6.116e-49	183.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,1ISIU@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
HKD3_k127_3580104_7	880071.Fleli_0641	8.855e-23	103.0	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,47YSU@768503|Cytophagia	976|Bacteroidetes	P	PFAM FixH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
HKD3_k127_3580104_0	929556.Solca_1394	3.901e-179	572.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
HKD3_k127_3580104_3	1123248.KB893386_gene1896	4.79e-51	185.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
HKD3_k127_360311_1	1131812.JQMS01000001_gene1221	1.388e-13	76.0	COG2010@1|root,COG2010@2|Bacteria,4PCRX@976|Bacteroidetes,1IDAA@117743|Flavobacteriia,2NXVD@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_360311_0	925409.KI911562_gene1047	6.594e-275	863.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD3_k127_3633048_0	1454007.JAUG01000062_gene589	3.744e-273	857.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
HKD3_k127_3658932_2	435591.BDI_1870	4.593e-15	76.0	COG0673@1|root,COG0673@2|Bacteria,4NENY@976|Bacteroidetes,2FWYJ@200643|Bacteroidia,22ZV9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_3658932_0	1185876.BN8_04207	6.506e-123	399.0	COG5285@1|root,COG5285@2|Bacteria,4NEH9@976|Bacteroidetes,47NTV@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
HKD3_k127_3658932_1	929713.NIASO_15895	3.792e-83	278.0	COG2303@1|root,COG2303@2|Bacteria,4NHJT@976|Bacteroidetes,1IRDW@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
HKD3_k127_3673159_1	925409.KI911562_gene207	3.352e-54	190.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
HKD3_k127_3673159_0	1267211.KI669560_gene956	4.648e-275	848.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HKD3_k127_3673159_2	113355.CM001775_gene2581	1.006e-26	115.0	COG3015@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,NlpE
HKD3_k127_3678165_5	1270193.JARP01000001_gene2573	2.117e-10	61.0	COG1917@1|root,COG1917@2|Bacteria,4NT85@976|Bacteroidetes,1I9VT@117743|Flavobacteriia,2NWSR@237|Flavobacterium	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3678165_0	925409.KI911562_gene237	1.546e-233	731.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1IQ95@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase, family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_3678165_1	1267211.KI669560_gene910	1.6e-178	567.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_3678165_4	485918.Cpin_1191	1.447e-41	156.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,1ITHM@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3678165_2	1123248.KB893315_gene3133	7.448e-81	275.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD3_k127_3678165_3	700598.Niako_7005	1.431e-53	190.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1IYWB@117747|Sphingobacteriia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
HKD3_k127_3679537_0	314278.NB231_01773	0.0	1101.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1WWMT@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_3696953_0	1123248.KB893348_gene361	9.293e-224	736.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_3696953_2	1121481.AUAS01000029_gene5305	6.051e-13	83.0	COG3391@1|root,COG4886@1|root,COG3391@2|Bacteria,COG4886@2|Bacteria,4NJXD@976|Bacteroidetes	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,DUF285,LRR_4,MucBP
HKD3_k127_3696953_1	1123248.KB893348_gene361	2.438e-87	317.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_3707605_5	649349.Lbys_2703	5.274e-34	133.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,47QBX@768503|Cytophagia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
HKD3_k127_3707605_4	1122621.ATZA01000011_gene416	5.01e-42	160.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_3707605_0	925409.KI911562_gene2192	7.13e-246	766.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1IPSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD3_k127_3707605_1	1123248.KB893370_gene5006	1.738e-180	574.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
HKD3_k127_3707605_3	1123248.KB893370_gene5005	1.602e-44	167.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1ISX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
HKD3_k127_3707605_7	1123248.KB893370_gene5004	6.67e-24	111.0	2DPQE@1|root,332Z6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3707605_6	925409.KI911562_gene2188	4.016e-32	129.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,1ITYX@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HKD3_k127_3707605_2	1123248.KB893370_gene5002	3.036e-91	311.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1IP2P@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD3_k127_3707605_9	1267211.KI669560_gene1655	2.997e-05	47.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1IPC8@117747|Sphingobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD3_k127_3732553_0	925409.KI911562_gene800	2.035e-205	647.0	COG0155@1|root,COG0155@2|Bacteria,4NENW@976|Bacteroidetes	976|Bacteroidetes	C	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	cysI	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HKD3_k127_3732553_1	700598.Niako_6983	7.162e-138	450.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,1IQMJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
HKD3_k127_3739901_1	247639.MGP2080_01521	4.043e-11	68.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_3739901_0	1163407.UU7_04927	1.387e-46	179.0	COG2885@1|root,COG2885@2|Bacteria,1RB3C@1224|Proteobacteria,1S36Z@1236|Gammaproteobacteria,1X77V@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
HKD3_k127_3747273_0	700598.Niako_4480	3.048e-146	483.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_3747273_1	700598.Niako_5484	1.479e-135	441.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
HKD3_k127_3747273_2	1123248.KB893318_gene4149	1.564e-107	353.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1IPT2@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
HKD3_k127_3747273_3	700598.Niako_5482	1.003e-87	299.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_3755273_1	1123248.KB893319_gene4048	1.573e-79	277.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1IS1E@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3755273_4	925409.KI911562_gene448	2.803e-58	213.0	28NPZ@1|root,2ZBPQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_3755273_5	1123248.KB893348_gene259	8.743e-12	77.0	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3755273_3	1123248.KB893348_gene258	2.685e-63	221.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_3755273_0	925409.KI911562_gene757	4.779e-229	721.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IW1A@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HKD3_k127_3755273_2	696747.NIES39_C05180	4.916e-66	250.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
HKD3_k127_3755273_6	1267211.KI669560_gene1609	1.607e-10	66.0	2EUHG@1|root,33MZM@2|Bacteria,4NZ9U@976|Bacteroidetes,1IZZA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3760485_3	700598.Niako_2620	3.89e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,4NSXH@976|Bacteroidetes,1ITK2@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_3760485_0	1122931.AUAE01000007_gene1160	5.864e-303	947.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,2FMF9@200643|Bacteroidia,22W4V@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
HKD3_k127_3760485_2	1123276.KB893245_gene1477	4.481e-178	567.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,47K2U@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_3760485_1	411476.BACOVA_01687	2.504e-216	695.0	COG3537@1|root,COG4225@1|root,COG4733@1|root,COG3537@2|Bacteria,COG4225@2|Bacteria,COG4733@2|Bacteria,4NDYB@976|Bacteroidetes,2FMQ9@200643|Bacteroidia,4AMFS@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_3760485_4	926550.CLDAP_17960	8.725e-30	121.0	COG1874@1|root,COG1874@2|Bacteria,2G8ZR@200795|Chloroflexi	200795|Chloroflexi	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
HKD3_k127_3779301_4	1121930.AQXG01000001_gene1402	1.512e-23	103.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3779301_3	1268240.ATFI01000003_gene5117	9.526e-26	110.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,2FSJ8@200643|Bacteroidia,4AQWN@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
HKD3_k127_3779301_0	1122605.KB893626_gene2754	1.769e-184	586.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD3_k127_3779301_5	1434325.AZQN01000003_gene2770	1.706e-15	89.0	COG1361@1|root,COG1404@1|root,COG4932@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG4932@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia	976|Bacteroidetes	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
HKD3_k127_3779301_2	1121481.AUAS01000005_gene2065	7.082e-31	137.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,47S36@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_3779301_1	925409.KI911562_gene450	1.608e-48	176.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1ISQF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3779301_6	388413.ALPR1_16883	6.821e-08	57.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	PKD,Pro_isomerase
HKD3_k127_378580_0	1454007.JAUG01000116_gene643	3.212e-195	623.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD3_k127_380304_3	1216967.L100_04117	1.04e-17	83.0	COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,1I2UN@117743|Flavobacteriia,34RGG@308865|Elizabethkingia	976|Bacteroidetes	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
HKD3_k127_380304_1	1121904.ARBP01000016_gene5234	2.587e-41	156.0	COG0454@1|root,COG0456@2|Bacteria,4NQCD@976|Bacteroidetes,47RMK@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_380304_0	485918.Cpin_4713	2.107e-192	606.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD3_k127_380304_2	471854.Dfer_0319	1.999e-33	147.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43,fn3
HKD3_k127_3807118_2	700598.Niako_4730	3.575e-196	641.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IPHQ@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
HKD3_k127_3807118_0	700598.Niako_2562	0.0	1141.0	COG1640@1|root,COG1640@2|Bacteria,4NF7Z@976|Bacteroidetes,1IPKN@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	CBM_20,Glyco_hydro_77
HKD3_k127_3807118_1	1267211.KI669560_gene2176	8.552e-246	766.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
HKD3_k127_3815980_7	1267211.KI669560_gene347	7.982e-19	96.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,Cadherin-like,Calx-beta,Flg_new
HKD3_k127_3815980_0	925409.KI911562_gene510	2.724e-127	412.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1IQAN@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
HKD3_k127_3815980_1	1492738.FEM21_15140	3.09e-116	385.0	COG1819@1|root,COG1819@2|Bacteria,4NFYF@976|Bacteroidetes,1HZ4S@117743|Flavobacteriia,2NUVB@237|Flavobacterium	976|Bacteroidetes	CG	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
HKD3_k127_3815980_6	1123277.KB893174_gene5927	1.453e-53	201.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_3815980_5	700598.Niako_2039	3.493e-58	211.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1IXPB@117747|Sphingobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_3815980_4	1239962.C943_01704	2.617e-58	215.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
HKD3_k127_3815980_2	1120965.AUBV01000013_gene1305	2.999e-67	241.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
HKD3_k127_3815980_3	485918.Cpin_0500	4.506e-62	216.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1IQ9R@117747|Sphingobacteriia	976|Bacteroidetes	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD3_k127_3824376_0	925409.KI911562_gene776	0.0	1427.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD3_k127_3824376_1	1123277.KB893184_gene3952	1.826e-207	655.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,47KFD@768503|Cytophagia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HKD3_k127_3824376_3	1233950.IW22_11110	5.135e-44	164.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1I1Z9@117743|Flavobacteriia,3ZRMD@59732|Chryseobacterium	976|Bacteroidetes	K	Rrf2 family transcriptional regulator	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD3_k127_3824376_2	760192.Halhy_1807	8.845e-110	359.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1IPQ0@117747|Sphingobacteriia	976|Bacteroidetes	O	AhpC TSA family	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
HKD3_k127_3833625_1	1239962.C943_03434	1.18e-42	161.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3833625_0	1122176.KB903537_gene1704	2.484e-280	889.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IR3P@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_3852434_1	925409.KI911562_gene2987	0.0	1305.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HKD3_k127_3852434_3	485918.Cpin_4048	7.788e-110	362.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,1IQTJ@117747|Sphingobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD3_k127_3852434_0	1123248.KB893314_gene3546	0.0	2478.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1IP5J@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HKD3_k127_3852434_4	700598.Niako_0909	5.46e-89	303.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes,1IUAK@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
HKD3_k127_3852434_2	925409.KI911562_gene2353	7.817e-162	514.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_3859459_1	925409.KI911562_gene2046	6.854e-100	329.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HKD3_k127_3859459_2	929713.NIASO_09685	2.794e-68	243.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1IQ5D@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HKD3_k127_3859459_0	485918.Cpin_6517	0.0	1089.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1INMK@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD3_k127_3859459_4	700598.Niako_2636	1.216e-37	149.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1ISVD@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD3_k127_3859459_3	1227739.Hsw_1672	5.153e-42	159.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,47Q28@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_3871819_1	700598.Niako_2543	7.24e-107	353.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_3871819_2	925409.KI911562_gene2210	1.494e-46	175.0	2ADZU@1|root,313SD@2|Bacteria,4PK7E@976|Bacteroidetes,1IUKW@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
HKD3_k127_3871819_0	929713.NIASO_09020	1.349e-151	484.0	COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,1J0R0@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_3871819_3	1144313.PMI10_01402	4.729e-46	169.0	COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,1I4WB@117743|Flavobacteriia,2NWWP@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
HKD3_k127_3906786_2	1121859.KB890757_gene1571	2.671e-92	310.0	COG4913@1|root,COG4913@2|Bacteria,4NFA3@976|Bacteroidetes	976|Bacteroidetes	S	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
HKD3_k127_3906786_6	485918.Cpin_1055	8.915e-22	94.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD3_k127_3906786_0	761193.Runsl_4070	3.079e-148	481.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,47K31@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
HKD3_k127_3906786_5	700598.Niako_6599	6.14e-23	104.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1IT9C@117747|Sphingobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD3_k127_3906786_4	1122605.KB893626_gene2806	1.203e-40	151.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD3_k127_3906786_1	925409.KI911562_gene485	2.754e-115	378.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1IQ92@117747|Sphingobacteriia	976|Bacteroidetes	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HKD3_k127_3906786_3	1408813.AYMG01000039_gene2275	8.178e-44	175.0	COG0793@1|root,COG0793@2|Bacteria,4NIQJ@976|Bacteroidetes,1IXGI@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
HKD3_k127_3928157_1	700598.Niako_2188	3.669e-90	299.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_3928157_0	313606.M23134_06918	5.62e-106	350.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47JWT@768503|Cytophagia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
HKD3_k127_3939427_2	1117379.BABA_11536	6.792e-85	294.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,1ZB5J@1386|Bacillus	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	dgoD	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_3939427_1	1121481.AUAS01000001_gene4753	6.373e-86	290.0	COG1028@1|root,COG1028@2|Bacteria,4NGYN@976|Bacteroidetes,47NHS@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
HKD3_k127_3939427_4	1460635.JCM19038_867	2.314e-51	192.0	COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD3_k127_3939427_0	471854.Dfer_5256	1.125e-213	667.0	COG4948@1|root,COG4948@2|Bacteria,4NIIJ@976|Bacteroidetes,47XJS@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_3939427_3	1347086.CCBA010000025_gene3114	4.167e-63	227.0	COG3386@1|root,COG3386@2|Bacteria,1V1TK@1239|Firmicutes,4HG0A@91061|Bacilli,1ZAVX@1386|Bacillus	91061|Bacilli	G	SMP-30/Gluconolaconase/LRE-like region	yvrE	GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
HKD3_k127_3939427_5	1121373.KB903640_gene3754	8.723e-40	160.0	COG2017@1|root,COG2017@2|Bacteria,4NKUK@976|Bacteroidetes,47KGR@768503|Cytophagia	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HKD3_k127_3964675_1	1121104.AQXH01000001_gene2164	4.002e-174	555.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
HKD3_k127_3964675_0	1122621.ATZA01000013_gene3285	8.983e-197	624.0	COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
HKD3_k127_3964675_2	925409.KI911562_gene1266	7.133e-37	139.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
HKD3_k127_3987650_3	358681.BBR47_00290	8.37e-20	93.0	2C4H4@1|root,32X9D@2|Bacteria,1VCB6@1239|Firmicutes,4HKJT@91061|Bacilli,26TSY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3987650_2	1121889.AUDM01000017_gene2156	5.824e-21	94.0	2EG2M@1|root,339UK@2|Bacteria,4NZ5V@976|Bacteroidetes,1IBQ9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3987650_1	1237149.C900_03318	1.072e-98	327.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD3_k127_3987650_0	1267211.KI669560_gene1375	1.117e-132	434.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IX27@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_4008977_4	1123248.KB893320_gene3928	1.109e-19	88.0	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,1IQ14@117747|Sphingobacteriia	976|Bacteroidetes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD3_k127_4008977_3	945713.IALB_2441	3.154e-24	106.0	2CCSR@1|root,32RWC@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_4008977_1	1123248.KB893320_gene3929	9.487e-75	252.0	COG0822@1|root,COG0822@2|Bacteria,4NM9Z@976|Bacteroidetes,1IS99@117747|Sphingobacteriia	976|Bacteroidetes	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HKD3_k127_4008977_2	1267211.KI669560_gene1040	9.567e-59	206.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1IT1Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD3_k127_4008977_0	700598.Niako_3552	3.853e-156	502.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IVSZ@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0553 Superfamily II DNA RNA helicase SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
HKD3_k127_4009778_3	929556.Solca_2930	1.764e-49	183.0	COG3266@1|root,COG3266@2|Bacteria,4NMES@976|Bacteroidetes,1IUMC@117747|Sphingobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4009778_2	1341181.FLJC2902T_28210	4.748e-69	238.0	COG4319@1|root,COG4319@2|Bacteria,4NRTT@976|Bacteroidetes,1I3HR@117743|Flavobacteriia,2NWDQ@237|Flavobacterium	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_4009778_1	700598.Niako_4357	2.43e-136	440.0	COG1092@1|root,COG1092@2|Bacteria,4P1C0@976|Bacteroidetes,1IVC8@117747|Sphingobacteriia	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HKD3_k127_4009778_0	1267211.KI669560_gene518	1.806e-263	826.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_4010884_3	1123248.KB893386_gene1879	9.229e-06	49.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
HKD3_k127_4010884_0	925409.KI911562_gene745	1.355e-79	275.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1IXDH@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_4010884_1	925409.KI911562_gene744	4.926e-54	199.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1ITFC@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
HKD3_k127_4010884_2	762903.Pedsa_3119	5.115e-38	149.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes	976|Bacteroidetes	M	NlpC p60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HKD3_k127_4039949_0	1123248.KB893314_gene3606	7.673e-48	173.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD3_k127_4039949_1	929713.NIASO_19370	2.977e-40	152.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1IZAC@117747|Sphingobacteriia	976|Bacteroidetes	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
HKD3_k127_4039949_2	1267211.KI669560_gene1365	1.977e-38	147.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HKD3_k127_4040753_1	1123248.KB893386_gene1984	4.185e-93	310.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HKD3_k127_4040753_0	700598.Niako_5645	3.937e-105	347.0	COG1018@1|root,COG1018@2|Bacteria,4PN6Y@976|Bacteroidetes	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523,ko:K05784	ko00362,ko00364,ko00520,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00520,map00622,map01100,map01120,map01220	M00551	R03391,R03392,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00230,RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD3_k127_4040753_3	700598.Niako_7211	8.433e-42	157.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HKD3_k127_4040753_2	700598.Niako_7212	3.748e-90	301.0	COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,1IQCF@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HKD3_k127_4085707_0	700598.Niako_5604	3.288e-245	764.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD3_k127_4085707_1	700598.Niako_0113	1.032e-21	96.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1IR3G@117747|Sphingobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
HKD3_k127_4086107_4	925409.KI911562_gene2042	3.159e-65	228.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1IPJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HKD3_k127_4086107_2	925409.KI911562_gene2041	3.596e-82	287.0	COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,1IR2J@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_4086107_1	700598.Niako_4925	9.088e-104	345.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_4086107_0	1123248.KB893337_gene2596	1.437e-170	539.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1IP0K@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
HKD3_k127_4086107_3	700598.Niako_6999	1.861e-81	284.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_4088094_3	699248.SRA_05916	6.936e-29	123.0	COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,4HG4F@91061|Bacilli	91061|Bacilli	M	Domain of unknown function (DUF4422)	cps3J	-	-	-	-	-	-	-	-	-	-	-	DUF4422
HKD3_k127_4088094_0	1121481.AUAS01000013_gene4310	8.312e-173	556.0	COG0562@1|root,COG0562@2|Bacteria,4NGXU@976|Bacteroidetes,47KQW@768503|Cytophagia	976|Bacteroidetes	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
HKD3_k127_4088094_2	404589.Anae109_0378	1.789e-46	177.0	COG3306@1|root,COG3306@2|Bacteria,1NGNU@1224|Proteobacteria	1224|Proteobacteria	M	PFAM glycosyl transferase family 25	-	-	-	ko:K07270	-	-	-	-	ko00000	-	GT25	-	Glyco_transf_25
HKD3_k127_4088094_1	1123248.KB893370_gene5009	1.726e-55	197.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_4103658_2	1267211.KI669560_gene344	1.863e-73	259.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
HKD3_k127_4103658_0	925409.KI911562_gene732	1.124e-172	546.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1IQZ5@117747|Sphingobacteriia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HKD3_k127_4103658_1	1123248.KB893331_gene3759	2.141e-136	439.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
HKD3_k127_4103658_3	1121887.AUDK01000010_gene1413	3.145e-20	91.0	2C82G@1|root,32RK9@2|Bacteria,4NSXV@976|Bacteroidetes,1I466@117743|Flavobacteriia,2NX9M@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
HKD3_k127_4150671_2	1122605.KB893625_gene2252	2.397e-95	323.0	COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes	976|Bacteroidetes	HJ	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	RimK
HKD3_k127_4150671_0	925409.KI911562_gene2892	2.539e-143	462.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1IP0Z@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
HKD3_k127_4150671_1	700598.Niako_1599	2.301e-141	452.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD3_k127_4153025_0	700598.Niako_3302	1.156e-242	777.0	COG1520@1|root,COG1520@2|Bacteria	700598.Niako_3302|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4153025_1	700598.Niako_4439	7.763e-117	389.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1IYZU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
HKD3_k127_4153025_2	760192.Halhy_4420	1.42e-86	290.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD3_k127_4161587_0	1267211.KI669560_gene16	1.164e-221	694.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IP88@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD3_k127_4161587_1	929713.NIASO_13025	5.659e-77	262.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD3_k127_4198351_1	700598.Niako_2024	2.535e-65	234.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1IP1J@117747|Sphingobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
HKD3_k127_4198351_0	925409.KI911562_gene2439	5.123e-171	543.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD3_k127_4198351_2	1123248.KB893337_gene2466	1.742e-60	217.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1IYXS@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
HKD3_k127_4198612_1	1358423.N180_15385	2.09e-75	267.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1IPJ8@117747|Sphingobacteriia	976|Bacteroidetes	DM	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
HKD3_k127_4198612_3	1453500.AT05_02265	1.649e-25	117.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
HKD3_k127_4198612_2	873513.HMPREF6485_1789	5.554e-26	118.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,2FNYD@200643|Bacteroidia	976|Bacteroidetes	M	Polysaccharide biosynthesis export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
HKD3_k127_4198612_0	700598.Niako_1623	6.812e-106	352.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IP25@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
HKD3_k127_426342_3	700598.Niako_3669	6.107e-27	114.0	COG1502@1|root,COG1502@2|Bacteria,4P0CZ@976|Bacteroidetes,1J0D9@117747|Sphingobacteriia	976|Bacteroidetes	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HKD3_k127_426342_2	468059.AUHA01000003_gene1728	1.502e-56	204.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,1IW0G@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
HKD3_k127_426342_1	1121875.KB907549_gene1743	8.353e-66	231.0	COG1073@1|root,COG1073@2|Bacteria,4NMFG@976|Bacteroidetes,1I1R1@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
HKD3_k127_426342_0	700598.Niako_5795	1.588e-121	394.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
HKD3_k127_4278998_1	929556.Solca_1368	3.087e-99	336.0	COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,1IS2Y@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_4278998_0	925409.KI911562_gene2871	1.031e-209	655.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD3_k127_4278998_2	1270196.JCKI01000001_gene3551	1.103e-40	154.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1IPFY@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
HKD3_k127_4284095_1	686340.Metal_0729	1.879e-09	64.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,1SAWR@1236|Gammaproteobacteria,1XFGD@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
HKD3_k127_4284095_0	714943.Mucpa_1830	5.708e-18	98.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IPF5@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_4289362_4	700598.Niako_0309	7.351e-41	154.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD3_k127_4289362_1	700598.Niako_0308	9.092e-108	350.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD3_k127_4289362_2	700598.Niako_5253	6.96e-99	329.0	COG1723@1|root,COG1723@2|Bacteria,4NFED@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
HKD3_k127_4289362_0	1123248.KB893315_gene3210	0.0	1290.0	COG3408@1|root,COG3408@2|Bacteria,4PKJG@976|Bacteroidetes,1IQX7@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
HKD3_k127_4289362_3	1123248.KB893321_gene543	2.248e-54	194.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
HKD3_k127_4314170_1	700598.Niako_5481	2.882e-91	310.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
HKD3_k127_4314170_0	1123248.KB893314_gene3638	6.172e-136	439.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1IQEQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HKD3_k127_4314170_2	1123248.KB893314_gene3639	3.327e-81	273.0	COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,1IS83@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD3_k127_4315814_8	1123234.AUKI01000016_gene2974	1.036e-14	75.0	2A8XB@1|root,30Y0U@2|Bacteria,4NSDA@976|Bacteroidetes,1I4EZ@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_4315814_5	1123248.KB893319_gene3968	1.471e-69	240.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1IST1@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_4315814_1	1122605.KB893626_gene2525	1.069e-104	344.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1INPX@117747|Sphingobacteriia	976|Bacteroidetes	C	oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_4315814_7	1122605.KB893626_gene2526	7.974e-32	129.0	COG5605@1|root,COG5605@2|Bacteria,4PGS2@976|Bacteroidetes,1IU6V@117747|Sphingobacteriia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
HKD3_k127_4315814_3	700598.Niako_6480	6.228e-79	272.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD3_k127_4315814_2	1267211.KI669560_gene118	1.072e-85	287.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ITGM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
HKD3_k127_4315814_6	761193.Runsl_0671	1.521e-42	165.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
HKD3_k127_4315814_4	1123277.KB893195_gene5660	2.611e-70	240.0	COG2080@1|root,COG2080@2|Bacteria,4NMVV@976|Bacteroidetes,47Q3P@768503|Cytophagia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD3_k127_4315814_0	700598.Niako_0547	3.845e-250	785.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IR1H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD3_k127_4361400_3	925409.KI911562_gene1161	6.638e-90	299.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_4361400_0	1267211.KI669560_gene861	9.074e-261	816.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1IPMR@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD3_k127_4361400_2	700598.Niako_6857	1.682e-97	329.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1IQ08@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility associated	gldN	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4361400_1	700598.Niako_6856	5.321e-123	411.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
HKD3_k127_4361400_4	1267211.KI669560_gene858	1.165e-86	293.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1ISRG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4361400_5	1123248.KB893359_gene2112	3.167e-69	235.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1IP8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD3_k127_4361567_1	1121875.KB907549_gene1998	1.25e-98	328.0	COG0428@1|root,COG0428@2|Bacteria,4NHR7@976|Bacteroidetes,1HZWS@117743|Flavobacteriia	976|Bacteroidetes	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
HKD3_k127_4361567_3	1110502.TMO_1264	1.109e-14	77.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,2JPJI@204441|Rhodospirillales	204441|Rhodospirillales	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HKD3_k127_4361567_2	1379270.AUXF01000007_gene997	2.727e-95	324.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_4361567_0	1042326.AZNV01000038_gene5891	1.146e-98	328.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,2UQIK@28211|Alphaproteobacteria,4BIGR@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
HKD3_k127_4361603_3	1239962.C943_03831	1.001e-43	164.0	2C0UK@1|root,32ZTA@2|Bacteria,4NUQ2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4361603_0	1433126.BN938_2808	2.431e-208	664.0	COG3203@1|root,COG3203@2|Bacteria,4NPX9@976|Bacteroidetes,2FXT1@200643|Bacteroidia	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
HKD3_k127_4361603_1	1239962.C943_03829	4.167e-143	456.0	COG1028@1|root,COG1028@2|Bacteria	1239962.C943_03829|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4361603_2	1239962.C943_03828	6.79e-123	398.0	COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,47MT3@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.159,1.3.1.25	ko:K00076,ko:K05783	ko00121,ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00121,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113	RC00271,RC01326,RC01327	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD3_k127_4371218_6	700598.Niako_6958	3.745e-05	46.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
HKD3_k127_4371218_4	485918.Cpin_4192	3.54e-33	131.0	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1IZ3T@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_4371218_5	266265.Bxe_A1247	7.636e-29	121.0	COG3556@1|root,COG3556@2|Bacteria,1N0ZZ@1224|Proteobacteria,2WFT6@28216|Betaproteobacteria,1KI5R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
HKD3_k127_4371218_2	1185876.BN8_02240	9.933e-85	299.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47M2K@768503|Cytophagia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_4371218_1	1123248.KB893331_gene3799	1.328e-196	619.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD3_k127_4371218_3	925409.KI911562_gene1233	3.83e-38	147.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ITMH@117747|Sphingobacteriia	976|Bacteroidetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD3_k127_4371218_0	1123248.KB893331_gene3797	6.138e-243	766.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPEH@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_4381064_0	1120965.AUBV01000003_gene631	0.0	1266.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47M4G@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD3_k127_4381064_1	760192.Halhy_1903	2.305e-185	591.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1INMD@117747|Sphingobacteriia	976|Bacteroidetes	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_4381064_2	768706.Desor_1586	8.283e-13	71.0	2EIQA@1|root,33CFR@2|Bacteria,1W559@1239|Firmicutes,254YN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4397475_1	929713.NIASO_07770	1.007e-54	193.0	COG1607@1|root,COG1607@2|Bacteria,4NNG1@976|Bacteroidetes	976|Bacteroidetes	I	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_4397475_0	1123242.JH636434_gene5275	1.559e-154	502.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
HKD3_k127_4424699_0	929562.Emtol_1426	0.0	1128.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_4424699_1	1123278.KB893412_gene2912	2.822e-36	144.0	COG1017@1|root,COG1017@2|Bacteria,4NS54@976|Bacteroidetes,47QWP@768503|Cytophagia	976|Bacteroidetes	C	Globin	-	-	-	-	-	-	-	-	-	-	-	-	Globin
HKD3_k127_4424699_2	929713.NIASO_00550	3.394e-13	77.0	COG0526@1|root,COG0526@2|Bacteria,4NY16@976|Bacteroidetes	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_4489699_1	1122605.KB893645_gene1209	2.397e-105	345.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1IV0I@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_4489699_0	925409.KI911562_gene2106	5.403e-245	763.0	COG0731@1|root,COG0731@2|Bacteria,4PNUE@976|Bacteroidetes,1J0SJ@117747|Sphingobacteriia	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_4489699_2	1123248.KB893337_gene2490	9.914e-91	304.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1ISM8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Sulfite exporter TauE SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_4489699_4	1267211.KI669560_gene1544	3.781e-06	49.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	MA20_03510	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_4529538_0	925409.KI911562_gene2343	8.213e-175	561.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_4529538_1	1122605.KB893645_gene985	4.335e-32	126.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HKD3_k127_4586021_2	391587.KAOT1_06217	1.463e-104	353.0	COG0438@1|root,COG0438@2|Bacteria,4NE53@976|Bacteroidetes,1HX83@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD3_k127_4586021_4	1121904.ARBP01000005_gene4698	8.192e-67	242.0	COG0438@1|root,COG0438@2|Bacteria,4NIXA@976|Bacteroidetes,47U8T@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_4586021_0	1121897.AUGO01000004_gene904	6.783e-186	597.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2NVCP@237|Flavobacterium	976|Bacteroidetes	E	Glutamine amidotransferase domain	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_4586021_1	1094466.KQS_03395	4.72e-129	420.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1I0MG@117743|Flavobacteriia,2NTJP@237|Flavobacterium	976|Bacteroidetes	M	Polyhydroxyalkanoate synthesis repressor PhaR	neuB	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
HKD3_k127_4586021_3	1305737.JAFX01000001_gene1742	1.436e-96	319.0	COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,47NJS@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.183,3.2.1.184	ko:K08068,ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
HKD3_k127_4610375_0	700598.Niako_2568	0.0	1357.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IP63@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
HKD3_k127_4610375_2	1121890.AUDO01000003_gene1694	1.684e-50	199.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1HYGI@117743|Flavobacteriia,2NT3F@237|Flavobacterium	976|Bacteroidetes	MU	outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_4610375_1	700598.Niako_2570	1.114e-68	236.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1IRVT@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HKD3_k127_4617486_1	696747.NIES39_C05180	3.656e-26	115.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
HKD3_k127_4617486_2	348824.LPU83_1849	1.068e-10	71.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K12944	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	HAD_2,NUDIX
HKD3_k127_4617486_0	1123276.KB893245_gene1427	8.515e-62	226.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
HKD3_k127_462486_2	1121930.AQXG01000008_gene213	7.313e-27	112.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1IQVK@117747|Sphingobacteriia	976|Bacteroidetes	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HKD3_k127_462486_3	313606.M23134_05847	8.347e-26	118.0	COG3221@1|root,COG3221@2|Bacteria,4NR53@976|Bacteroidetes,47R3T@768503|Cytophagia	976|Bacteroidetes	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
HKD3_k127_462486_1	1122605.KB893648_gene3600	5.531e-32	126.0	COG4281@1|root,COG4281@2|Bacteria,4NVK0@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-coA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ACBP
HKD3_k127_462486_0	925409.KI911562_gene2265	3.459e-92	308.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HKD3_k127_462486_4	929713.NIASO_18340	1.646e-07	54.0	28N3K@1|root,32XIJ@2|Bacteria,4PKCA@976|Bacteroidetes,1J0D7@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD3_k127_462486_5	1499683.CCFF01000016_gene529	1.425e-06	59.0	COG5662@1|root,COG5662@2|Bacteria,1UHWV@1239|Firmicutes,24JF8@186801|Clostridia,36INK@31979|Clostridiaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
HKD3_k127_4629858_3	1123278.KB893433_gene684	2.99e-37	146.0	COG2273@1|root,COG2273@2|Bacteria,4NF91@976|Bacteroidetes,47MDE@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Glyco_hydro_16,Glyco_hydro_43
HKD3_k127_4629858_2	1380600.AUYN01000009_gene1522	8.398e-104	343.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	SASA
HKD3_k127_4629858_1	1089547.KB913013_gene4670	3.525e-214	676.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
HKD3_k127_4629858_0	1089547.KB913013_gene4669	5.363e-291	929.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_4653003_0	1121890.AUDO01000008_gene2801	2.326e-100	332.0	COG3119@1|root,COG3119@2|Bacteria,4NF21@976|Bacteroidetes,1HZ1G@117743|Flavobacteriia,2NVDT@237|Flavobacterium	976|Bacteroidetes	P	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
HKD3_k127_4653003_2	925409.KI911562_gene2459	2.438e-38	151.0	COG3787@1|root,COG3787@2|Bacteria,4NSSF@976|Bacteroidetes,1ITM3@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:Pyridox_oxidase	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
HKD3_k127_4653003_1	1267211.KI669560_gene1006	1.382e-56	204.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD3_k127_4653003_3	1121481.AUAS01000020_gene5210	9.243e-16	79.0	28ME7@1|root,2ZARX@2|Bacteria,4P47D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_4669960_0	1123248.KB893332_gene2278	5.187e-94	314.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_4669960_2	1107311.Q767_01830	7.037e-11	64.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1HY94@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_4669960_1	700598.Niako_5413	2.74e-52	194.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_470190_3	1123248.KB893326_gene1427	2.083e-28	115.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_470190_2	925409.KI911562_gene2487	2.149e-78	269.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1IS1B@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_470190_1	700598.Niako_1226	1.592e-104	345.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1IQ5P@117747|Sphingobacteriia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HKD3_k127_470190_0	1150600.ADIARSV_2959	3.886e-249	797.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4NG28@976|Bacteroidetes,1IQJ9@117747|Sphingobacteriia	976|Bacteroidetes	KT	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
HKD3_k127_4724596_0	1123248.KB893348_gene80	2.316e-318	988.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD3_k127_4733881_0	867902.Ornrh_0091	2.642e-212	666.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HKD3_k127_4760831_0	700598.Niako_1224	1.68e-239	761.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4760831_1	1123248.KB893326_gene1426	1.647e-49	186.0	COG0860@1|root,COG0860@2|Bacteria,4P1J0@976|Bacteroidetes,1IVQV@117747|Sphingobacteriia	976|Bacteroidetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD3_k127_4764346_6	1267211.KI669560_gene2097	1.078e-43	161.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes	976|Bacteroidetes	EGP	Major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
HKD3_k127_4764346_0	700598.Niako_5054	1.194e-214	674.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1IPZ7@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_4764346_1	700598.Niako_5052	7.271e-175	555.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,1INRW@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
HKD3_k127_4764346_4	1123276.KB893251_gene3597	7.348e-50	187.0	arCOG10603@1|root,32SV6@2|Bacteria,4NFE9@976|Bacteroidetes,47RY3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4764346_5	929713.NIASO_04365	4.17e-49	181.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,1ITWU@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K01802,ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HKD3_k127_4764346_2	1123248.KB893323_gene1605	1.335e-150	488.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1IV2A@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HKD3_k127_4764346_3	700598.Niako_4582	3.133e-134	434.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1IPT6@117747|Sphingobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HKD3_k127_4764346_7	1120965.AUBV01000014_gene1204	1.589e-24	105.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,47KID@768503|Cytophagia	976|Bacteroidetes	J	RNA-binding PUA-like domain of methyltransferase RsmF	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
HKD3_k127_4783887_2	1122605.KB893646_gene80	3.108e-68	239.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1ISUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
HKD3_k127_4783887_0	929713.NIASO_13960	5.545e-294	917.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HKD3_k127_4783887_1	925409.KI911562_gene1081	2.16e-120	391.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1IP93@117747|Sphingobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD3_k127_4787098_1	472759.Nhal_2106	5.046e-67	235.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria,1WXV0@135613|Chromatiales	135613|Chromatiales	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_4787098_0	1107311.Q767_10395	4.19e-207	653.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1HWM0@117743|Flavobacteriia,2NTAJ@237|Flavobacterium	976|Bacteroidetes	J	metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HKD3_k127_4806670_6	1123248.KB893319_gene4064	2.453e-06	53.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_4806670_2	1267211.KI669560_gene743	7.809e-144	464.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1IWHK@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD3_k127_4806670_4	925409.KI911562_gene1075	1.333e-50	186.0	COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,1IYNI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
HKD3_k127_4806670_1	700598.Niako_6051	1.127e-149	481.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
HKD3_k127_4806670_0	391596.PBAL39_11297	0.0	1092.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD3_k127_4806670_5	762903.Pedsa_2829	3.024e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes,1ITRX@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4806670_3	1123248.KB893331_gene3804	3.317e-120	397.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1IPQ3@117747|Sphingobacteriia	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
HKD3_k127_4845898_2	760192.Halhy_3267	2.938e-63	221.0	COG2085@1|root,COG2085@2|Bacteria,4NEC7@976|Bacteroidetes,1IXVK@117747|Sphingobacteriia	976|Bacteroidetes	S	Rossmann-like domain	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
HKD3_k127_4845898_0	929562.Emtol_3439	4.724e-145	465.0	COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,47K2N@768503|Cytophagia	976|Bacteroidetes	C	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
HKD3_k127_4845898_3	1239962.C943_01258	7.687e-41	154.0	COG1733@1|root,COG1733@2|Bacteria,4NQ5S@976|Bacteroidetes,47QMW@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD3_k127_4862240_0	1123248.KB893319_gene4038	4.054e-133	427.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1IQSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HKD3_k127_4862240_3	1123248.KB893319_gene4039	1.692e-59	207.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1ISJG@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HKD3_k127_4862240_2	1123248.KB893319_gene4040	1.047e-80	270.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HKD3_k127_4862240_4	1123248.KB893314_gene3602	1.926e-19	96.0	2CFIN@1|root,302AR@2|Bacteria,4PJAS@976|Bacteroidetes,1IZWV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4862240_1	925409.KI911562_gene815	4.665e-96	318.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,1ISA7@117747|Sphingobacteriia	976|Bacteroidetes	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
HKD3_k127_4871689_3	1267211.KI669560_gene1024	2.736e-172	548.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IWKA@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
HKD3_k127_4871689_0	1267211.KI669560_gene1023	0.0	1482.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_4871689_2	1267211.KI669560_gene1022	1.148e-241	756.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes	976|Bacteroidetes	M	RagB, SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_4871689_1	1267211.KI669560_gene1021	0.0	1007.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_4871689_5	1267211.KI669560_gene1021	8.472e-136	441.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_4871689_6	1270196.JCKI01000009_gene3386	4.27e-83	287.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IY37@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD3_k127_4871689_4	700598.Niako_6049	4.099e-161	511.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1IQCT@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_4881370_1	1123248.KB893330_gene439	6.778e-231	721.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,1IV6I@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Alpha amylase, catalytic	malL	-	3.2.1.1,3.2.1.10,5.4.99.16	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
HKD3_k127_4881370_0	1086011.HJ01_01311	1.235e-237	739.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia,2NSEU@237|Flavobacterium	976|Bacteroidetes	G	Major Facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
HKD3_k127_4918374_3	649349.Lbys_2887	1.256e-60	214.0	COG1225@1|root,COG1225@2|Bacteria,4NNHI@976|Bacteroidetes,47PTD@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD3_k127_4918374_1	700598.Niako_4487	2.62e-98	335.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,1J0IU@117747|Sphingobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HKD3_k127_4918374_2	1500281.JQKZ01000039_gene1823	6.526e-62	216.0	COG0454@1|root,COG0456@2|Bacteria,4NP44@976|Bacteroidetes,1I196@117743|Flavobacteriia,3ZRRU@59732|Chryseobacterium	976|Bacteroidetes	K	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
HKD3_k127_4918374_4	1454007.JAUG01000007_gene2184	1.111e-51	188.0	COG1670@1|root,COG1670@2|Bacteria,4NPHU@976|Bacteroidetes,1ITAI@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HKD3_k127_4918374_5	1086011.HJ01_03171	5.561e-29	118.0	2E3H7@1|root,32YFW@2|Bacteria,4NVEF@976|Bacteroidetes,1I52A@117743|Flavobacteriia,2NXWF@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4918374_0	929562.Emtol_3375	0.0	1109.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
HKD3_k127_4942853_1	1406840.Q763_08060	7.406e-65	229.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NSID@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_4942853_0	1267211.KI669560_gene2387	4.655e-98	323.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HKD3_k127_4981392_0	700598.Niako_0308	2.622e-71	242.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD3_k127_4981392_1	1267211.KI669560_gene1283	9.086e-57	203.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD3_k127_4981392_2	925409.KI911562_gene1538	1.853e-37	143.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1INM0@117747|Sphingobacteriia	976|Bacteroidetes	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_4985317_6	1121875.KB907549_gene2024	2.062e-23	101.0	COG2303@1|root,COG2303@2|Bacteria,4NMEP@976|Bacteroidetes,1IA7R@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
HKD3_k127_4985317_5	1185876.BN8_02923	3.96e-40	157.0	2C25Y@1|root,3399H@2|Bacteria,4NXDI@976|Bacteroidetes,47SDB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4985317_1	925409.KI911562_gene1632	1.309e-119	394.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1IPXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_4985317_2	700598.Niako_2019	1.029e-99	337.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD3_k127_4985317_4	925409.KI911562_gene2271	4.775e-70	241.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1IRWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
HKD3_k127_4985317_3	925409.KI911562_gene2270	3.371e-99	331.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD3_k127_4985317_0	1121889.AUDM01000006_gene1496	4.18e-183	578.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,1HWT1@117743|Flavobacteriia,2NSVM@237|Flavobacterium	976|Bacteroidetes	P	arsenical-resistance protein	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
HKD3_k127_4985317_7	755732.Fluta_3069	1.773e-12	67.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,1HYIW@117743|Flavobacteriia,2PBST@246874|Cryomorphaceae	976|Bacteroidetes	T	Protein tyrosine phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD3_k127_4995628_8	929703.KE386491_gene1952	2.291e-34	133.0	COG4221@1|root,COG4221@2|Bacteria,4NHEQ@976|Bacteroidetes,47M62@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_4995628_0	700598.Niako_5667	6.928e-286	900.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_4995628_3	1267211.KI669560_gene2870	4.6e-98	327.0	COG4760@1|root,COG4760@2|Bacteria,4NNIN@976|Bacteroidetes,1IXW4@117747|Sphingobacteriia	976|Bacteroidetes	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
HKD3_k127_4995628_7	1237149.C900_00250	5.62e-37	150.0	28J3Q@1|root,32URP@2|Bacteria,4NT50@976|Bacteroidetes,47R3P@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_4995628_5	760192.Halhy_0310	1.19e-87	308.0	COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,1IWXD@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_4995628_4	925409.KI911562_gene420	7.328e-96	318.0	COG0745@1|root,COG0745@2|Bacteria,4NMAD@976|Bacteroidetes,1J08B@117747|Sphingobacteriia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_4995628_9	1120965.AUBV01000003_gene445	2.12e-26	113.0	2DNUQ@1|root,32Z94@2|Bacteria,4NVH0@976|Bacteroidetes,47QAG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
HKD3_k127_4995628_1	700598.Niako_6597	7.849e-124	402.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1IPZH@117747|Sphingobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HKD3_k127_4995628_2	1166018.FAES_5125	9.418e-124	411.0	COG0793@1|root,COG0793@2|Bacteria,4NM82@976|Bacteroidetes,47PRW@768503|Cytophagia	976|Bacteroidetes	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N,TPR_2
HKD3_k127_4995628_6	700598.Niako_6054	5.887e-58	204.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1IPSX@117747|Sphingobacteriia	976|Bacteroidetes	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
HKD3_k127_49994_1	1298608.JCM18900_1443	1.347e-61	216.0	COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,1S2UY@1236|Gammaproteobacteria,3NKSF@468|Moraxellaceae	1236|Gammaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_49994_2	1267211.KI669560_gene2053	2.892e-51	187.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD3_k127_49994_0	700598.Niako_0416	5.25e-136	438.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_5009112_4	925409.KI911562_gene494	4.035e-07	52.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD3_k127_5009112_1	1123248.KB893322_gene626	5.744e-110	362.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_5009112_2	743722.Sph21_4366	1.535e-77	263.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1IQD8@117747|Sphingobacteriia	976|Bacteroidetes	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HKD3_k127_5009112_0	1123248.KB893322_gene627	3.015e-155	501.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1IX4W@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_5009112_3	468059.AUHA01000003_gene1698	2.36e-66	236.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1IT3V@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,SusF_SusE,TPR_2
HKD3_k127_5020008_15	485918.Cpin_6975	4.104e-47	169.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HKD3_k127_5020008_2	700598.Niako_7321	1.405e-199	630.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD3_k127_5020008_6	1267211.KI669560_gene1189	2.152e-154	498.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD3_k127_5020008_8	1123248.KB893329_gene4489	3.748e-138	450.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD3_k127_5020008_4	700598.Niako_7324	5.521e-163	525.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_5020008_14	925409.KI911562_gene104	9.819e-49	187.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IRV2@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
HKD3_k127_5020008_1	700598.Niako_7326	3.131e-204	648.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1IQJQ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
HKD3_k127_5020008_3	700598.Niako_7327	4.979e-199	638.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1IR5B@117747|Sphingobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HKD3_k127_5020008_10	1123248.KB893386_gene1980	7.851e-98	328.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1IQB7@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
HKD3_k127_5020008_13	700598.Niako_7329	1.813e-52	194.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,1IZB2@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
HKD3_k127_5020008_9	700598.Niako_7330	2.143e-112	374.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1IVCP@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_5020008_0	1267211.KI669560_gene2720	0.0	1121.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1INUN@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_5020008_20	1227739.Hsw_0577	0.0002511	49.0	2CEPF@1|root,2ZR55@2|Bacteria,4P826@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5020008_17	1189612.A33Q_1247	9.624e-23	105.0	2E7UT@1|root,3329Q@2|Bacteria,4NUQ3@976|Bacteroidetes,47SB3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5020008_16	762903.Pedsa_1902	1.936e-37	145.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1IY8D@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD3_k127_5020008_18	1122951.ATUE01000006_gene1229	7.071e-15	76.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,3NMXP@468|Moraxellaceae	1236|Gammaproteobacteria	I	AMP-binding enzyme	fadD	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
HKD3_k127_5020008_5	1484460.JSWG01000011_gene1711	5.183e-157	508.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
HKD3_k127_5020008_7	1279009.ADICEAN_03525	1.237e-148	484.0	COG0671@1|root,COG0671@2|Bacteria,4NGYP@976|Bacteroidetes,47M29@768503|Cytophagia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_5020008_19	1121890.AUDO01000001_gene872	4.607e-06	55.0	28V2E@1|root,2ZUEY@2|Bacteria,4PKBB@976|Bacteroidetes,1IJ6C@117743|Flavobacteriia,2NT40@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369
HKD3_k127_5020008_12	743722.Sph21_0742	5.607e-65	228.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1INSA@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD3_k127_5020008_11	925409.KI911562_gene1461	5.432e-93	308.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
HKD3_k127_5021518_2	1123248.KB893348_gene361	1.115e-63	243.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_5021518_1	1123248.KB893348_gene360	1.063e-144	467.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1IR38@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5021518_0	1123248.KB893348_gene361	1.465e-226	731.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_5022179_0	925409.KI911562_gene1439	0.0	1012.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HKD3_k127_5022179_1	1408813.AYMG01000011_gene742	1.667e-30	134.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,4NDZC@976|Bacteroidetes,1IQEG@117747|Sphingobacteriia	976|Bacteroidetes	P	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD3_k127_5026951_3	313606.M23134_05676	0.0001075	47.0	COG4783@1|root,COG4783@2|Bacteria,4NTS7@976|Bacteroidetes	976|Bacteroidetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HKD3_k127_5026951_1	1121875.KB907549_gene1937	1.046e-23	106.0	COG1670@1|root,COG1670@2|Bacteria,4NPQC@976|Bacteroidetes,1I27J@117743|Flavobacteriia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_5026951_0	925409.KI911562_gene494	4.683e-72	245.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD3_k127_5026951_2	1123248.KB893322_gene626	2.592e-23	100.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_5060167_4	1267211.KI669560_gene848	5.498e-13	69.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1IQJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Outer membrane cobalamin receptor protein	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
HKD3_k127_5060167_3	700598.Niako_6839	1.789e-23	101.0	2DS1S@1|root,33E5G@2|Bacteria,4NYB0@976|Bacteroidetes,1IUIB@117747|Sphingobacteriia	976|Bacteroidetes	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
HKD3_k127_5060167_0	929556.Solca_2720	2.193e-93	309.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1IQJB@117747|Sphingobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
HKD3_k127_5060167_1	1121373.KB903636_gene804	1.146e-86	302.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,47NEW@768503|Cytophagia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HKD3_k127_5060167_5	742767.HMPREF9456_00468	9.31e-05	46.0	COG1722@1|root,COG1722@2|Bacteria,4NXJV@976|Bacteroidetes,2FVH6@200643|Bacteroidia,22YWF@171551|Porphyromonadaceae	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HKD3_k127_5060167_2	10228.TriadP58018	8.896e-39	150.0	COG0456@1|root,KOG3139@2759|Eukaryota,3A5U0@33154|Opisthokonta	33154|Opisthokonta	S	Acetyltransferase (GNAT) domain	-	GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_5072040_0	1123248.KB893314_gene3588	8.908e-148	470.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_5072040_2	1237149.C900_02632	2.064e-28	117.0	COG4095@1|root,COG4095@2|Bacteria	2|Bacteria	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
HKD3_k127_5072040_1	700598.Niako_5479	2.877e-40	151.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,1ITH1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
HKD3_k127_5072040_4	1476583.DEIPH_ctg079orf0049	1.203e-05	49.0	COG1126@1|root,COG1126@2|Bacteria,1WI0Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type polar amino acid transport system ATPase component	-	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
HKD3_k127_5074082_1	700598.Niako_3925	2.57e-127	413.0	COG0226@1|root,COG0226@2|Bacteria,4PKPM@976|Bacteroidetes,1J0PW@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_5074082_4	925409.KI911562_gene2426	3.827e-53	195.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1IRTX@117747|Sphingobacteriia	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
HKD3_k127_5074082_2	991.IW20_17040	1.106e-126	413.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
HKD3_k127_5074082_3	1122605.KB893631_gene3903	1.097e-60	228.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	BatD,TPR_16,TPR_2,TPR_6,TPR_8
HKD3_k127_5074082_0	925409.KI911562_gene2407	0.0	1335.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IQJH@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD3_k127_5074082_5	1123248.KB893370_gene4986	7.136e-40	156.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1ITV6@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_5081061_2	498848.TaqDRAFT_4878	6.195e-21	100.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5081061_0	700598.Niako_6492	4.872e-101	342.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_5081061_1	925409.KI911562_gene1041	1.729e-77	261.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1IRYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, asnc family	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD3_k127_5110660_4	216432.CA2559_11223	1.422e-30	128.0	COG0657@1|root,COG0657@2|Bacteria,4NFTX@976|Bacteroidetes,1I0SN@117743|Flavobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HKD3_k127_5110660_3	1123248.KB893330_gene398	2.554e-151	490.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_5110660_2	700598.Niako_7075	2.655e-163	526.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HKD3_k127_5110660_1	1123248.KB893314_gene3389	2.824e-171	550.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HKD3_k127_5110660_0	925409.KI911562_gene202	1.862e-192	609.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
HKD3_k127_5111830_0	1267211.KI669560_gene1277	1.119e-122	402.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1IRGQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_5111830_2	945713.IALB_2990	6.152e-49	183.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4397
HKD3_k127_5111830_1	700598.Niako_5077	4.149e-107	353.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD3_k127_5111830_3	929713.NIASO_19250	7.571e-38	149.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes,1IT1C@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_5122451_2	700598.Niako_0370	3.359e-05	47.0	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,1IVUJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_5122451_0	1123248.KB893323_gene1617	4.725e-49	181.0	2DKFZ@1|root,309D6@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HKD3_k127_5122451_1	448385.sce3974	5.959e-34	140.0	COG3506@1|root,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	yjl217W	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
HKD3_k127_5129116_1	1267211.KI669560_gene2699	7.008e-92	308.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1ISGE@117747|Sphingobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
HKD3_k127_5129116_0	700598.Niako_1610	2.236e-242	755.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_5134437_1	1487953.JMKF01000037_gene3241	2.237e-31	140.0	COG1680@1|root,COG2931@1|root,COG1680@2|Bacteria,COG2931@2|Bacteria,1G5C3@1117|Cyanobacteria,1HAVU@1150|Oscillatoriales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
HKD3_k127_5134437_0	1341181.FLJC2902T_30120	8.971e-301	937.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NUEZ@237|Flavobacterium	976|Bacteroidetes	P	Cation transport ATPase (P-type)	yoaB	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD3_k127_5159014_3	468059.AUHA01000002_gene1345	1.448e-28	116.0	COG1566@1|root,COG1566@2|Bacteria,4PM5Z@976|Bacteroidetes,1J0IM@117747|Sphingobacteriia	976|Bacteroidetes	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
HKD3_k127_5159014_1	1123248.KB893337_gene2381	1.064e-144	473.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1IRU6@117747|Sphingobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_5159014_2	1123057.P872_10930	9.37e-51	183.0	COG0346@1|root,COG0346@2|Bacteria,4NQCJ@976|Bacteroidetes,47QR5@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_5159014_0	1267211.KI669560_gene2101	0.0	1168.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1IQP6@117747|Sphingobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HKD3_k127_5159491_1	469383.Cwoe_0091	3.612e-31	127.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria,4CR13@84995|Rubrobacteria	84995|Rubrobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	RPE65
HKD3_k127_5159491_0	1121930.AQXG01000012_gene3233	8.573e-161	519.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1IQI6@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1233 Phytoene dehydrogenase and related	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_5167818_4	1443665.JACA01000023_gene3675	2.933e-11	74.0	COG3858@1|root,COG3858@2|Bacteria,4NJZ6@976|Bacteroidetes,1I1G8@117743|Flavobacteriia,2YIKN@290174|Aquimarina	976|Bacteroidetes	S	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Glyco_hydro_18,Laminin_G_3
HKD3_k127_5167818_6	7739.XP_002608476.1	9.998e-06	57.0	KOG3714@1|root,KOG3714@2759|Eukaryota	2759|Eukaryota	O	metalloendopeptidase activity	-	-	3.4.24.19	ko:K05502	-	-	-	-	ko00000,ko01000,ko01002,ko04052	-	-	-	Astacin,CUB
HKD3_k127_5167818_1	468059.AUHA01000004_gene2343	6.559e-144	465.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1IP4Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_5167818_2	1356852.N008_17300	5.631e-140	453.0	COG0415@1|root,COG0415@2|Bacteria,4NFZG@976|Bacteroidetes,47KH9@768503|Cytophagia	976|Bacteroidetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	FAD_binding_7
HKD3_k127_5167818_3	1249997.JHZW01000003_gene3609	4.375e-34	133.0	COG2963@1|root,COG2963@2|Bacteria,4NSB9@976|Bacteroidetes,1I3XZ@117743|Flavobacteriia,2PIPI@252356|Maribacter	976|Bacteroidetes	L	Protein of unknown function (DUF2805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2805
HKD3_k127_5167818_5	552811.Dehly_0963	9.18e-06	54.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD3_k127_5167818_0	1121481.AUAS01000018_gene431	8.337e-179	569.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,47N6N@768503|Cytophagia	976|Bacteroidetes	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
HKD3_k127_5169268_2	925409.KI911562_gene291	3.391e-104	344.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_5169268_0	1123248.KB893324_gene1756	6.971e-152	488.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1IQ3E@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_5169268_5	761193.Runsl_3244	1.056e-28	125.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,47R92@768503|Cytophagia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_5169268_1	485918.Cpin_1222	5.876e-132	434.0	COG3746@1|root,COG3746@2|Bacteria,4NIRE@976|Bacteroidetes,1IVNH@117747|Sphingobacteriia	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
HKD3_k127_5169268_4	700598.Niako_6887	1.672e-45	168.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HKD3_k127_5183853_0	925409.KI911562_gene305	1.493e-205	643.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1IYHV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HKD3_k127_5183853_2	929562.Emtol_0801	6.316e-132	429.0	COG1816@1|root,COG1816@2|Bacteria,4NJ8S@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
HKD3_k127_5183853_1	761193.Runsl_2021	3.166e-151	488.0	COG5434@1|root,COG5434@2|Bacteria,4NE9Y@976|Bacteroidetes,47KM6@768503|Cytophagia	976|Bacteroidetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_5183853_3	929562.Emtol_1104	4.05e-57	206.0	COG5434@1|root,COG5434@2|Bacteria,4NFZJ@976|Bacteroidetes,47K9P@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,fn3
HKD3_k127_5187103_3	1122605.KB893643_gene910	9.418e-44	160.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_5187103_4	925409.KI911562_gene2354	2.955e-26	112.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1ITVJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
HKD3_k127_5187103_2	1123248.KB893337_gene2584	3.229e-66	235.0	COG0457@1|root,COG0457@2|Bacteria,4NXQQ@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5187103_0	1267211.KI669560_gene1776	6.89e-167	535.0	COG0534@1|root,COG0534@2|Bacteria,4NFIR@976|Bacteroidetes,1IXI6@117747|Sphingobacteriia	976|Bacteroidetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD3_k127_5187103_1	700598.Niako_0151	1.379e-96	319.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1INTB@117747|Sphingobacteriia	976|Bacteroidetes	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_5191547_0	700598.Niako_7025	3.202e-193	627.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1IUYM@117747|Sphingobacteriia	976|Bacteroidetes	G	Galactose mutarotase-like	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31
HKD3_k127_5191547_1	700598.Niako_5039	2.816e-152	494.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1IQ41@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD3_k127_5196531_7	42099.EPrPV00000014028	3.781e-09	69.0	COG4642@1|root,KOG0231@2759|Eukaryota,1MEV2@121069|Pythiales	121069|Pythiales	S	Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	MORN
HKD3_k127_5196531_8	388467.A19Y_4030	1.793e-07	59.0	2EAE0@1|root,334HK@2|Bacteria,1G9Z9@1117|Cyanobacteria,1HD9X@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5196531_5	1168289.AJKI01000065_gene3754	7.001e-41	157.0	COG0664@1|root,COG0664@2|Bacteria,4PIYN@976|Bacteroidetes,2G26P@200643|Bacteroidia,3XKX5@558415|Marinilabiliaceae	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_5196531_0	1121957.ATVL01000008_gene4409	8.732e-272	856.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47UBJ@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_5196531_3	1267211.KI669560_gene347	2.06e-50	193.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,Cadherin-like,Calx-beta,Flg_new
HKD3_k127_5196531_2	1239962.C943_03686	2.382e-57	209.0	2ESVF@1|root,33KDU@2|Bacteria,4NZ9D@976|Bacteroidetes,47SQC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5196531_6	1123276.KB893252_gene3675	9.346e-38	151.0	28ME7@1|root,2ZARX@2|Bacteria,4P47D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_5196531_1	1189612.A33Q_3569	2.013e-108	353.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_5196531_4	1123248.KB893385_gene4735	1.469e-48	180.0	COG1835@1|root,COG1835@2|Bacteria,4P0FC@976|Bacteroidetes,1IYEI@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD3_k127_5231129_1	700598.Niako_0385	1.772e-95	325.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1IRH3@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
HKD3_k127_5231129_0	1267211.KI669560_gene1016	0.0	1252.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
HKD3_k127_5233400_3	926551.KB900703_gene1048	8.535e-10	70.0	COG5434@1|root,COG5434@2|Bacteria,4NR38@976|Bacteroidetes,1IIJB@117743|Flavobacteriia	976|Bacteroidetes	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_5233400_2	929556.Solca_4311	1.377e-50	193.0	COG3206@1|root,COG3206@2|Bacteria,4NH8F@976|Bacteroidetes,1INN0@117747|Sphingobacteriia	976|Bacteroidetes	M	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5233400_1	28229.ND2E_2313	2.724e-118	401.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,2Q6GG@267889|Colwelliaceae	1236|Gammaproteobacteria	E	PFAM asparagine synthase, glutamine amidotransferase class-II	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_5233400_0	929556.Solca_4303	3.96e-187	612.0	COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,1IPNG@117747|Sphingobacteriia	976|Bacteroidetes	M	export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
HKD3_k127_5236440_2	485918.Cpin_4038	1.057e-84	286.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,1ISCN@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD3_k127_5236440_1	700598.Niako_0381	3.521e-110	362.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1IQGT@117747|Sphingobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_5236440_0	925409.KI911562_gene2961	6.671e-194	625.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1ISVQ@117747|Sphingobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
HKD3_k127_5236440_3	700598.Niako_0427	1.399e-56	210.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1ISCP@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
HKD3_k127_5240799_5	1453505.JASY01000003_gene2181	5.511e-23	99.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia,2NUVN@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
HKD3_k127_5240799_2	485918.Cpin_2050	4.294e-145	474.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1INRC@117747|Sphingobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HKD3_k127_5240799_1	925409.KI911562_gene2590	9.604e-201	629.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,1IPQJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
HKD3_k127_5240799_0	925409.KI911562_gene2591	1.393e-241	755.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IP9C@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_5240799_3	925409.KI911562_gene2592	1.441e-47	171.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1ISXI@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
HKD3_k127_5240799_4	1267211.KI669560_gene1504	4.279e-45	164.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1IT8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD3_k127_5262086_0	1358423.N180_16420	3.912e-155	494.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1IRNQ@117747|Sphingobacteriia	976|Bacteroidetes	F	Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
HKD3_k127_5262086_1	649349.Lbys_0225	1.148e-19	95.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,47QN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5266047_4	1123248.KB893348_gene123	1.995e-18	86.0	2ACEV@1|root,3120D@2|Bacteria,4PGV7@976|Bacteroidetes,1IUFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5266047_0	313606.M23134_02854	6.999e-49	188.0	28N5Z@1|root,2ZBB2@2|Bacteria,4NK7G@976|Bacteroidetes,47NPT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5266047_2	1249997.JHZW01000002_gene959	1.409e-44	169.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,1I26T@117743|Flavobacteriia,2PHHR@252356|Maribacter	976|Bacteroidetes	K	FR47-like protein	paiA	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD3_k127_5266047_1	1107311.Q767_15005	1.358e-47	178.0	COG3485@1|root,COG3485@2|Bacteria,4NEZ1@976|Bacteroidetes,1I01Q@117743|Flavobacteriia,2NVGG@237|Flavobacterium	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
HKD3_k127_5266047_3	925409.KI911562_gene865	1.539e-37	141.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,1IR2B@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
HKD3_k127_5268256_6	709991.Odosp_1604	1.319e-08	66.0	COG3187@1|root,COG3187@2|Bacteria,4NRFE@976|Bacteroidetes,2FQEM@200643|Bacteroidia	976|Bacteroidetes	O	COG3187 Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	META
HKD3_k127_5268256_5	1121912.AUHD01000003_gene3023	4.623e-26	120.0	COG3187@1|root,COG3187@2|Bacteria,4PKCG@976|Bacteroidetes	976|Bacteroidetes	O	Domain of unknown function (DUF4377)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4377,META
HKD3_k127_5268256_1	1267211.KI669560_gene798	2.817e-177	563.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1IQFR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD3_k127_5268256_0	925409.KI911562_gene1123	6.722e-191	601.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_5268256_4	1121286.AUMT01000005_gene3173	9.327e-69	237.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia,3ZNQ9@59732|Chryseobacterium	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
HKD3_k127_5268256_2	929713.NIASO_01635	1.1e-143	460.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IPV3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD3_k127_5268256_3	761193.Runsl_3956	1.324e-120	396.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_5289259_0	1123248.KB893348_gene195	4.597e-86	291.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1ISF2@117747|Sphingobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_5289259_2	1086011.HJ01_02707	0.0007961	48.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes,1I4AH@117743|Flavobacteriia,2NWIC@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
HKD3_k127_5289259_1	925409.KI911562_gene472	9.766e-49	178.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HKD3_k127_5316767_0	929713.NIASO_00840	1.035e-310	1000.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
HKD3_k127_5316767_1	929562.Emtol_1304	5.846e-110	357.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,47K03@768503|Cytophagia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
HKD3_k127_5318319_0	1296415.JACC01000013_gene260	5.416e-87	293.0	COG1881@1|root,COG1881@2|Bacteria,4NKRU@976|Bacteroidetes,1HZIW@117743|Flavobacteriia	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
HKD3_k127_5318319_1	1278307.KB907039_gene1114	4.578e-53	196.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23,LTXXQ
HKD3_k127_5333605_2	925409.KI911562_gene251	1.357e-93	311.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1IR1N@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HKD3_k127_5333605_1	1123248.KB893315_gene3015	4.66e-148	477.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1IWIT@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
HKD3_k127_5333605_3	1123248.KB893318_gene4177	4.292e-50	190.0	2EPP0@1|root,33H9M@2|Bacteria,4NXT6@976|Bacteroidetes,1IYX8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5333605_0	1408813.AYMG01000014_gene1509	1.666e-211	667.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1IQD0@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD3_k127_5378613_2	925409.KI911562_gene2513	1.093e-41	159.0	COG0484@1|root,COG0484@2|Bacteria,4NSI9@976|Bacteroidetes,1ITFJ@117747|Sphingobacteriia	976|Bacteroidetes	O	HSCB C-terminal oligomerisation domain	-	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
HKD3_k127_5378613_1	525903.Taci_1617	9.061e-60	212.0	COG0640@1|root,COG0640@2|Bacteria,3TAVK@508458|Synergistetes	508458|Synergistetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5378613_0	468059.AUHA01000002_gene516	8.078e-194	613.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,1IPXE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD3_k127_5378613_3	1287488.HMPREF0671_00385	3.244e-36	147.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,2FNYD@200643|Bacteroidia	976|Bacteroidetes	M	Polysaccharide biosynthesis export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
HKD3_k127_5378613_4	1500281.JQKZ01000002_gene1504	7.817e-09	64.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,3ZP0A@59732|Chryseobacterium	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
HKD3_k127_5396291_0	929556.Solca_3807	1.305e-120	395.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1ISYB@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD3_k127_5396291_1	1279009.ADICEAN_02492	2.344e-113	370.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,47NZB@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HKD3_k127_5398294_4	743722.Sph21_2390	2.564e-17	82.0	COG2067@1|root,COG2067@2|Bacteria,4NGWZ@976|Bacteroidetes,1IY2K@117747|Sphingobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_5398294_3	1121481.AUAS01000004_gene1599	7.823e-25	108.0	2DQR8@1|root,33877@2|Bacteria,4NWHC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5398294_1	1270196.JCKI01000001_gene4036	4.789e-201	640.0	COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1IP90@117747|Sphingobacteriia	976|Bacteroidetes	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
HKD3_k127_5398294_0	485918.Cpin_0917	0.0	1114.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IPSM@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD3_k127_5398294_2	1121904.ARBP01000001_gene5820	4.078e-115	380.0	COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,47UEF@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
HKD3_k127_5398294_5	1313421.JHBV01000029_gene1878	1.51e-07	63.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Peptidase_M43,Reprolysin_4
HKD3_k127_5403141_2	1123248.KB893314_gene3427	3.183e-19	90.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1ITXJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5403141_0	1123248.KB893319_gene4078	3.587e-314	968.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD3_k127_5403141_1	1122605.KB893646_gene132	3.766e-58	205.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1ISJH@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD3_k127_5403141_3	700598.Niako_6218	1.254e-18	91.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HKD3_k127_5413041_0	700598.Niako_2849	9.268e-126	417.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQK1@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_5413041_1	1341181.FLJC2902T_06540	6.13e-62	218.0	COG1670@1|root,COG1670@2|Bacteria,4NMB7@976|Bacteroidetes,1II65@117743|Flavobacteriia,2P0AY@237|Flavobacterium	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_5413041_2	666681.M301_2226	9.677e-08	62.0	COG1846@1|root,COG1846@2|Bacteria,1RDGK@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	slyA	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	HTH_27,MarR,MarR_2
HKD3_k127_5420393_2	925409.KI911562_gene1090	1.082e-94	316.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_5420393_1	925409.KI911562_gene1089	7.365e-96	323.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_5420393_3	1267211.KI669560_gene753	8.613e-32	130.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1IU3P@117747|Sphingobacteriia	976|Bacteroidetes	S	GldH lipoprotein	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
HKD3_k127_5420393_0	700598.Niako_6628	2.317e-100	335.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1IQ8K@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD3_k127_5430816_0	1123248.KB893359_gene2115	9.714e-180	576.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD3_k127_5430816_3	1123248.KB893318_gene4142	1.031e-41	159.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1ISRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_5430816_1	1122605.KB893643_gene791	3.603e-123	400.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1INVP@117747|Sphingobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_5430816_2	700598.Niako_4326	2.642e-100	332.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1IP6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD3_k127_5438626_2	1123248.KB893339_gene2712	5.419e-05	51.0	COG2373@1|root,COG3391@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,4NTMR@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
HKD3_k127_5438626_0	1267211.KI669560_gene1901	4.89e-110	361.0	2AUDP@1|root,31K1P@2|Bacteria,4NRCQ@976|Bacteroidetes,1IYFT@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2452)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2452
HKD3_k127_5438626_1	1267211.KI669560_gene2458	5.922e-83	283.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IXCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD3_k127_544046_3	1123248.KB893348_gene157	1.035e-41	165.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1ITFP@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
HKD3_k127_544046_1	700598.Niako_6312	1.269e-84	286.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1IRZ0@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
HKD3_k127_544046_2	1123248.KB893348_gene153	3.234e-47	180.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1ITSR@117747|Sphingobacteriia	976|Bacteroidetes	E	Lysine exporter protein (Lyse ygga)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_544046_0	700598.Niako_6315	2.534e-239	749.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,1IVSR@117747|Sphingobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_5450803_1	925409.KI911562_gene13	5.54e-198	627.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
HKD3_k127_5450803_5	925409.KI911562_gene12	2.624e-139	448.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IPYS@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM (2R)-phospho-3-sulfolactate synthase ComA	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
HKD3_k127_5450803_7	700598.Niako_4702	2.597e-89	301.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
HKD3_k127_5450803_8	1267211.KI669560_gene2544	2.97e-40	152.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1INWV@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
HKD3_k127_5450803_3	1120965.AUBV01000013_gene1347	1.015e-150	480.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
HKD3_k127_5450803_6	1122605.KB893625_gene1989	2.417e-111	364.0	COG0586@1|root,COG0586@2|Bacteria,4NMPN@976|Bacteroidetes,1IWBE@117747|Sphingobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
HKD3_k127_5450803_0	1267211.KI669560_gene2542	4.176e-203	638.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_5450803_4	1123248.KB893323_gene1623	1.6e-150	481.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HKD3_k127_5450803_2	1267211.KI669560_gene2540	4.891e-181	571.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
HKD3_k127_5459224_0	925409.KI911562_gene2596	4.45e-133	464.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1INZH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_5459224_1	700598.Niako_0569	3.336e-112	367.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1IR2F@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
HKD3_k127_5459224_2	1123248.KB893314_gene3481	2.202e-80	281.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,1IT7E@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
HKD3_k127_5459224_3	1123248.KB893314_gene3482	2.248e-48	184.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VanZ
HKD3_k127_5471392_3	1347342.BN863_10510	1.823e-35	148.0	COG3746@1|root,COG3746@2|Bacteria,4NK5I@976|Bacteroidetes	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
HKD3_k127_5471392_2	1037409.BJ6T_58620	1.489e-42	164.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD3_k127_5471392_1	497965.Cyan7822_1833	8.51e-45	175.0	COG0628@1|root,COG0628@2|Bacteria,1G1UA@1117|Cyanobacteria,3KH99@43988|Cyanothece	1117|Cyanobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_5471392_0	118173.KB235914_gene4255	1.387e-166	536.0	COG4320@1|root,COG4320@2|Bacteria,1G0BG@1117|Cyanobacteria,1H91M@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
HKD3_k127_548369_1	925409.KI911562_gene1207	4.546e-108	356.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1IR07@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HKD3_k127_548369_0	700598.Niako_6927	1.244e-122	400.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1IQNE@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_548369_2	485918.Cpin_4197	1.875e-58	229.0	COG4733@1|root,COG4733@2|Bacteria,4PKY7@976|Bacteroidetes,1J0NC@117747|Sphingobacteriia	976|Bacteroidetes	O	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PPC,Reprolysin_4,fn3
HKD3_k127_548369_3	445961.IW15_21330	1.54e-50	205.0	292WA@1|root,2ZQDT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5535685_0	1123248.KB893385_gene4884	1.633e-147	472.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1IP5W@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock protein Hsp90	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
HKD3_k127_5535685_1	1313301.AUGC01000003_gene1964	1.246e-85	294.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes	976|Bacteroidetes	S	SMART transcription factor jumonji	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
HKD3_k127_5535685_4	153721.MYP_1679	6.104e-37	146.0	2DMYZ@1|root,32UGH@2|Bacteria,4NTDD@976|Bacteroidetes,47R9K@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
HKD3_k127_5535685_5	485918.Cpin_6372	7.299e-11	71.0	2961W@1|root,2ZTCE@2|Bacteria,4P91I@976|Bacteroidetes,1J023@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5535685_2	485918.Cpin_6371	8.105e-68	235.0	COG1595@1|root,COG1595@2|Bacteria,4NP5U@976|Bacteroidetes,1IS8X@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_5535685_3	929556.Solca_1000	1.634e-60	220.0	2ESVF@1|root,3018D@2|Bacteria,4PA48@976|Bacteroidetes,1IXND@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5542222_5	1123248.KB893385_gene4877	2.899e-54	197.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1IPJE@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
HKD3_k127_5542222_0	925409.KI911562_gene1444	1.049e-143	462.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1IPAD@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD3_k127_5542222_1	700598.Niako_5707	2.665e-98	333.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1INPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
HKD3_k127_5542222_2	1267211.KI669560_gene2724	3.133e-83	280.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD3_k127_5542222_3	485918.Cpin_0388	3.649e-73	258.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1ITHJ@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_5542222_4	925409.KI911562_gene1449	1.263e-57	203.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1ISTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HKD3_k127_5571_4	1121930.AQXG01000011_gene1757	1.825e-23	102.0	COG3324@1|root,COG3324@2|Bacteria,4NTUQ@976|Bacteroidetes,1IZ1H@117747|Sphingobacteriia	976|Bacteroidetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_5571_0	1123248.KB893331_gene3801	1.507e-143	479.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1IPZ1@117747|Sphingobacteriia	976|Bacteroidetes	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
HKD3_k127_5571_1	1123248.KB893331_gene3802	1.223e-120	404.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1IXCQ@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
HKD3_k127_5571_2	1356852.N008_11705	1.195e-104	365.0	28HFP@1|root,2Z7RP@2|Bacteria,4NHVI@976|Bacteroidetes,47NP6@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
HKD3_k127_5571_3	1121957.ATVL01000006_gene2931	2.073e-25	111.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,47KR7@768503|Cytophagia	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
HKD3_k127_5584587_0	700598.Niako_0370	3.354e-89	308.0	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,1IVUJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_5584587_1	761193.Runsl_0877	3.781e-60	212.0	28I6D@1|root,2Z89E@2|Bacteria,4NIIX@976|Bacteroidetes,47MYZ@768503|Cytophagia	976|Bacteroidetes	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
HKD3_k127_5600425_0	1267211.KI669560_gene518	1.125e-119	391.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_5600425_2	946077.W5A_13410	3.098e-06	58.0	2DND9@1|root,32WWR@2|Bacteria,4NTHN@976|Bacteroidetes,1I67I@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_5600425_1	1408813.AYMG01000042_gene5119	3.857e-90	329.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_5614705_2	1267211.KI669560_gene1440	2.464e-70	240.0	COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1IP6Q@117747|Sphingobacteriia	976|Bacteroidetes	G	glucose-1-phosphate adenylyltransferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD3_k127_5614705_1	1453500.AT05_10770	1.454e-200	634.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
HKD3_k127_5614705_0	925409.KI911562_gene2683	2.481e-227	719.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	amyA2	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
HKD3_k127_5637600_2	1122605.KB893628_gene4438	1.593e-14	75.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IPS5@117747|Sphingobacteriia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_5637600_1	1123248.KB893331_gene3771	2.279e-83	290.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IPS5@117747|Sphingobacteriia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_5637600_0	700598.Niako_6067	4.693e-230	718.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1INZ2@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
HKD3_k127_5643306_0	1123248.KB893319_gene4061	1.809e-251	790.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
HKD3_k127_5643306_1	1122605.KB893644_gene1363	3.361e-17	83.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
HKD3_k127_5652676_0	925409.KI911562_gene1196	4.141e-156	502.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_5656689_2	401053.AciPR4_1845	1.786e-65	232.0	COG3409@1|root,COG3409@2|Bacteria,3Y7KF@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
HKD3_k127_5656689_3	1120968.AUBX01000012_gene2673	2.752e-16	85.0	2CWBN@1|root,32SZD@2|Bacteria,4NU6S@976|Bacteroidetes,47VSE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5656689_1	1408445.JHXP01000025_gene533	3.263e-79	272.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1JECW@118969|Legionellales	118969|Legionellales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD3_k127_5656689_4	1380387.JADM01000007_gene501	6.389e-16	89.0	COG3126@1|root,COG3650@1|root,COG3126@2|Bacteria,COG3650@2|Bacteria,1N8AF@1224|Proteobacteria,1SCM7@1236|Gammaproteobacteria,1XS8E@135619|Oceanospirillales	135619|Oceanospirillales	S	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	YscW
HKD3_k127_5656689_0	1267211.KI669560_gene2834	4.129e-143	464.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_5671154_0	1450525.JATV01000010_gene1620	2.392e-124	413.0	COG2985@1|root,COG2985@2|Bacteria,4NEBW@976|Bacteroidetes,1HZIV@117743|Flavobacteriia,2P0F7@237|Flavobacterium	976|Bacteroidetes	U	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
HKD3_k127_5671154_1	700598.Niako_5814	8.113e-81	280.0	COG0457@1|root,COG0457@2|Bacteria,4NME3@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
HKD3_k127_5671154_3	643867.Ftrac_3103	1.75e-22	100.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes,47SBV@768503|Cytophagia	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
HKD3_k127_5671154_2	1267211.KI669560_gene165	1.165e-55	200.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IQD6@117747|Sphingobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
HKD3_k127_5679338_0	929562.Emtol_3111	1.866e-275	855.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_5689740_0	1216967.L100_08124	4.369e-163	520.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1HYPP@117743|Flavobacteriia,34QBZ@308865|Elizabethkingia	976|Bacteroidetes	EGP	Ion channel regulatory protein UNC-93	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
HKD3_k127_5689740_3	929556.Solca_0893	2.196e-18	86.0	COG3360@1|root,COG3360@2|Bacteria,4NURJ@976|Bacteroidetes,1IU3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
HKD3_k127_5689740_2	1120966.AUBU01000006_gene3345	1.133e-25	111.0	COG3187@1|root,COG3187@2|Bacteria,4NXH7@976|Bacteroidetes,47YNE@768503|Cytophagia	976|Bacteroidetes	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
HKD3_k127_5689740_1	485918.Cpin_3266	6.746e-116	377.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_569750_1	485918.Cpin_1275	4.365e-79	267.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_569750_0	925409.KI911562_gene1213	3.989e-112	367.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1IS3D@117747|Sphingobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
HKD3_k127_569750_2	1123248.KB893385_gene4778	3.625e-07	52.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_5706637_0	929703.KE386491_gene2730	5.46e-122	403.0	COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,47MN6@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HKD3_k127_5706637_1	1227739.Hsw_0986	2.246e-14	85.0	COG2831@1|root,COG2931@1|root,COG2831@2|Bacteria,COG2931@2|Bacteria,4PPJE@976|Bacteroidetes,47YRQ@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
HKD3_k127_5706637_2	762903.Pedsa_0723	3.426e-08	66.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,4NZAU@976|Bacteroidetes	976|Bacteroidetes	DZ	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5719730_3	1121286.AUMT01000022_gene1702	1.548e-69	249.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1HXBV@117743|Flavobacteriia,3ZR3I@59732|Chryseobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
HKD3_k127_5719730_1	700598.Niako_1866	1.258e-84	291.0	COG1105@1|root,COG1105@2|Bacteria,4NFZI@976|Bacteroidetes,1IR0I@117747|Sphingobacteriia	976|Bacteroidetes	G	belongs to the carbohydrate kinase PfkB family	pfkB	-	2.7.1.11,2.7.1.144	ko:K00917,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HKD3_k127_5719730_0	925409.KI911562_gene877	1.344e-110	366.0	COG2367@1|root,COG2367@2|Bacteria,4NDYP@976|Bacteroidetes,1INNE@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HKD3_k127_5719730_2	1123248.KB893331_gene3762	1.09e-71	248.0	28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1ISKT@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
HKD3_k127_5719730_4	236814.IX39_02500	1.132e-09	60.0	COG1073@1|root,COG1073@2|Bacteria,4NP3H@976|Bacteroidetes,1I92T@117743|Flavobacteriia,3ZPGU@59732|Chryseobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD3_k127_5735860_5	272559.BF9343_3279	1.076e-06	56.0	2ACE7@1|root,311ZQ@2|Bacteria,4PGUK@976|Bacteroidetes,2FYXK@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5735860_2	700598.Niako_4343	2.293e-78	267.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1ISWG@117747|Sphingobacteriia	976|Bacteroidetes	S	acr, cog1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
HKD3_k127_5735860_3	1123248.KB893326_gene1478	1.243e-26	109.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1IU0H@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HKD3_k127_5735860_0	700598.Niako_4345	5.092e-122	399.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HKD3_k127_5735860_4	1123248.KB893316_gene4578	1.28e-18	93.0	2ET5Y@1|root,33KQ0@2|Bacteria,4NZGA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5735860_1	1123248.KB893316_gene4577	1.591e-95	331.0	COG1629@1|root,COG4771@2|Bacteria,4PKB3@976|Bacteroidetes,1IPFQ@117747|Sphingobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
HKD3_k127_5758084_2	861299.J421_1115	8.479e-19	89.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5758084_1	929703.KE386491_gene2227	4.652e-20	96.0	COG0406@1|root,COG0406@2|Bacteria,4NQWA@976|Bacteroidetes,47SDA@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HKD3_k127_5758084_0	929713.NIASO_14470	1.029e-126	406.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD3_k127_5769268_2	388413.ALPR1_09308	1.121e-70	258.0	COG3307@1|root,COG3307@2|Bacteria,4NGIS@976|Bacteroidetes,47TK6@768503|Cytophagia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HKD3_k127_5769268_3	641526.ADIWIN_0423	1.417e-52	199.0	COG0438@1|root,COG0438@2|Bacteria,4NHHN@976|Bacteroidetes,1HZQ0@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_5769268_0	1086011.HJ01_00197	7.916e-113	375.0	COG0438@1|root,COG0438@2|Bacteria,4NU4C@976|Bacteroidetes,1I610@117743|Flavobacteriia,2NTSZ@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferases group 1	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
HKD3_k127_5769268_1	1131812.JQMS01000001_gene175	9.328e-101	336.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2NVCP@237|Flavobacterium	976|Bacteroidetes	E	Glutamine amidotransferase domain	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_5782311_3	700598.Niako_5270	2.361e-32	129.0	COG2050@1|root,COG2050@2|Bacteria,4NNXM@976|Bacteroidetes,1IY7V@117747|Sphingobacteriia	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
HKD3_k127_5782311_1	485918.Cpin_0141	1.178e-83	285.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,1IPTU@117747|Sphingobacteriia	976|Bacteroidetes	S	MOSC domain containing protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
HKD3_k127_5782311_0	1122605.KB893649_gene3721	4.411e-204	640.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HKD3_k127_5782311_2	649349.Lbys_0926	2.08e-56	197.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,47KPU@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_5794836_0	1267211.KI669560_gene2700	3.12e-297	915.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes	976|Bacteroidetes	E	Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
HKD3_k127_5802714_0	519989.ECTPHS_12697	8.011e-309	952.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1WXVD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
HKD3_k127_5802714_4	700598.Niako_6305	1.812e-40	153.0	2DNMN@1|root,32Y54@2|Bacteria,4NW3V@976|Bacteroidetes,1IYIN@117747|Sphingobacteriia	976|Bacteroidetes	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
HKD3_k127_5802714_2	1123248.KB893331_gene3768	1.025e-73	254.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1IY4A@117747|Sphingobacteriia	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD3_k127_5802714_3	700598.Niako_6303	4.512e-45	167.0	COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,1ITGU@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD3_k127_5802714_1	925409.KI911562_gene1093	4.451e-195	614.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,1INVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD3_k127_5857547_1	925409.KI911562_gene1202	1.333e-76	261.0	COG1629@1|root,COG4771@2|Bacteria,4PKRZ@976|Bacteroidetes,1J0Q2@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_5857547_7	1267211.KI669560_gene2811	4.341e-21	95.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
HKD3_k127_5857547_6	485918.Cpin_1235	3.168e-39	154.0	COG3063@1|root,COG3063@2|Bacteria,4PKEN@976|Bacteroidetes	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5857547_2	700598.Niako_6912	4.07e-50	184.0	295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,1IZ1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5857547_4	1267211.KI669560_gene2807	1.282e-43	160.0	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,1IZ1N@117747|Sphingobacteriia	976|Bacteroidetes	K	Winged helix DNA-binding domain	marR	-	-	-	-	-	-	-	-	-	-	-	HTH_34
HKD3_k127_5857547_3	1123248.KB893314_gene3618	1.446e-49	192.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	OMP_b-brl
HKD3_k127_5857547_0	1267211.KI669560_gene2862	1.409e-105	346.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1IPXY@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD3_k127_5887681_2	385682.AFSL01000100_gene44	2.255e-17	84.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,2FMB0@200643|Bacteroidia,3XK9P@558415|Marinilabiliaceae	976|Bacteroidetes	G	Alpha-L-fucosidase	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
HKD3_k127_5887681_1	1423321.AS29_05995	1.925e-33	133.0	COG5646@1|root,COG5646@2|Bacteria,1VJMY@1239|Firmicutes,4IAJM@91061|Bacilli,1ZN47@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD3_k127_5887681_0	925409.KI911562_gene2169	1.294e-112	368.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1IPB3@117747|Sphingobacteriia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HKD3_k127_5893082_2	1123248.KB893318_gene4206	3.086e-30	123.0	COG1280@1|root,COG1280@2|Bacteria,4NUV7@976|Bacteroidetes,1IUGQ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_5893082_0	1123248.KB893318_gene4193	3.504e-168	534.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1IT0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
HKD3_k127_5893082_1	1443665.JACA01000027_gene3903	4.632e-89	302.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1HWRH@117743|Flavobacteriia,2YIDF@290174|Aquimarina	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_5904102_0	1123248.KB893321_gene544	4.333e-234	737.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_5904102_1	700598.Niako_2189	1.588e-30	128.0	COG0845@1|root,COG0845@2|Bacteria,4NTDH@976|Bacteroidetes,1ITXB@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
HKD3_k127_5911881_4	700598.Niako_5066	1.446e-42	165.0	COG0683@1|root,COG0683@2|Bacteria,4PMPE@976|Bacteroidetes,1ISIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
HKD3_k127_5911881_0	1122605.KB893649_gene3876	4.605e-228	712.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1IPUW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD3_k127_5911881_2	700598.Niako_5643	4.387e-51	184.0	COG0454@1|root,COG0456@2|Bacteria,4NWTW@976|Bacteroidetes,1IZJT@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD3_k127_5911881_1	945713.IALB_2233	5.639e-96	327.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
HKD3_k127_5912546_0	485918.Cpin_7284	0.0	1265.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD3_k127_5912546_3	1120968.AUBX01000018_gene2161	1.292e-128	422.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,47JI6@768503|Cytophagia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD3_k127_5912546_7	700598.Niako_7036	1.477e-51	188.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1ISWU@117747|Sphingobacteriia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HKD3_k127_5912546_5	1123248.KB893314_gene3420	2.409e-69	238.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1IRXR@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD3_k127_5912546_1	1267211.KI669560_gene935	4.605e-228	712.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1INMC@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD3_k127_5912546_2	925409.KI911562_gene231	1.359e-147	471.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_5912546_6	700598.Niako_7032	2.603e-57	202.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1ISF1@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD3_k127_5912546_8	1267211.KI669560_gene931	4.264e-34	138.0	2E469@1|root,32Z27@2|Bacteria,4P4UV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5912546_4	925409.KI911562_gene233	9.218e-105	351.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_5926150_0	1123248.KB893315_gene3090	1.904e-152	494.0	COG1819@1|root,COG1819@2|Bacteria,4NIX4@976|Bacteroidetes,1IWR9@117747|Sphingobacteriia	976|Bacteroidetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
HKD3_k127_5926150_2	1123248.KB893348_gene323	2.366e-83	288.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Rho_RNA_bind
HKD3_k127_5926150_1	1123248.KB893348_gene324	1.083e-105	352.0	COG2972@1|root,COG2972@2|Bacteria,4NN11@976|Bacteroidetes,1IXVB@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_5935104_2	1123248.KB893314_gene3577	1.645e-145	479.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
HKD3_k127_5935104_1	1123248.KB893314_gene3577	5.592e-153	503.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
HKD3_k127_5935104_0	1267211.KI669560_gene904	3.222e-211	664.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1IQSD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_5935104_3	1123248.KB893314_gene3579	3.577e-25	107.0	COG0249@1|root,COG0249@2|Bacteria,4NEXA@976|Bacteroidetes,1IPHP@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
HKD3_k127_5940803_1	1239962.C943_00095	5.385e-29	120.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47NWH@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	pbpE	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
HKD3_k127_5940803_0	1358423.N180_16420	2.667e-136	439.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1IRNQ@117747|Sphingobacteriia	976|Bacteroidetes	F	Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
HKD3_k127_5951239_2	487796.Flav2ADRAFT_1166	1.587e-15	78.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,1HYAU@117743|Flavobacteriia	976|Bacteroidetes	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HKD3_k127_5951239_1	1121875.KB907552_gene306	3.921e-100	337.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,1HZEI@117743|Flavobacteriia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
HKD3_k127_5951239_0	1379270.AUXF01000007_gene964	7.399e-229	720.0	COG0308@1|root,COG0308@2|Bacteria,1ZU50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_5972160_0	1123248.KB893329_gene4480	2.184e-63	223.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,1IWHH@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD3_k127_5972160_3	1123248.KB893348_gene344	1.433e-13	79.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5972160_2	700598.Niako_5511	6.767e-47	184.0	2EB10@1|root,3351W@2|Bacteria,4NV9Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5972160_1	925409.KI911562_gene1613	9.38e-57	203.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1IS44@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_5974286_2	1121875.KB907549_gene2024	1.69e-80	275.0	COG2303@1|root,COG2303@2|Bacteria,4NMEP@976|Bacteroidetes,1IA7R@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
HKD3_k127_5974286_0	760192.Halhy_3337	3.158e-243	768.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1INSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HKD3_k127_5974286_3	1267211.KI669560_gene2470	2.912e-76	261.0	COG0637@1|root,COG0637@2|Bacteria,4NID6@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
HKD3_k127_5974286_1	1267211.KI669560_gene2469	3.733e-115	376.0	COG0204@1|root,COG0204@2|Bacteria,4NG70@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_5974286_4	925409.KI911562_gene1896	3.987e-19	88.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1IRU4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
HKD3_k127_6003262_1	1499683.CCFF01000017_gene2043	9.121e-59	215.0	COG2267@1|root,COG2267@2|Bacteria,1UYT5@1239|Firmicutes,25BD5@186801|Clostridia,36WDU@31979|Clostridiaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD3_k127_6003262_0	1123234.AUKI01000011_gene1297	4.427e-60	213.0	COG1595@1|root,COG1595@2|Bacteria,4NM7R@976|Bacteroidetes,1I1GD@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6003262_2	1123234.AUKI01000011_gene1298	1.249e-52	197.0	COG0346@1|root,COG0346@2|Bacteria,4NRR0@976|Bacteroidetes	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_6003262_4	929562.Emtol_0656	3.443e-22	107.0	COG1246@1|root,COG1246@2|Bacteria,4NVX0@976|Bacteroidetes,47SE9@768503|Cytophagia	976|Bacteroidetes	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_6003262_3	421531.IX38_21775	1.165e-29	123.0	COG0454@1|root,COG0456@2|Bacteria,4NKGU@976|Bacteroidetes,1HZFA@117743|Flavobacteriia,3ZRA7@59732|Chryseobacterium	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_6025002_1	592029.DDD_1837	8.041e-24	102.0	COG3654@1|root,COG3654@2|Bacteria,4P630@976|Bacteroidetes	976|Bacteroidetes	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
HKD3_k127_6025002_0	700598.Niako_6435	0.0	1094.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes	976|Bacteroidetes	L	SNF2 family N-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HKD3_k127_6031838_4	1123248.KB893314_gene3266	0.0004132	44.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1IPU4@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
HKD3_k127_6031838_3	925409.KI911562_gene1797	9.219e-57	211.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1IQKS@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_6031838_0	1123248.KB893385_gene4842	2.657e-143	485.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1IPP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD3_k127_6031838_2	925409.KI911562_gene1795	1.338e-94	316.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1IPMS@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
HKD3_k127_6031838_1	700598.Niako_2007	6.231e-126	417.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1IQ33@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HKD3_k127_6049661_1	1123248.KB893314_gene3632	5.113e-137	455.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
HKD3_k127_6049661_0	1267211.KI669560_gene1042	7.31e-150	481.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1IQW6@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
HKD3_k127_6058755_1	1123248.KB893316_gene4543	2.783e-80	270.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1IQIF@117747|Sphingobacteriia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD3_k127_6058755_3	1454007.JAUG01000079_gene4539	4.044e-30	125.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,1INX3@117747|Sphingobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD3_k127_6058755_0	1123248.KB893316_gene4542	1.556e-200	634.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1IQIH@117747|Sphingobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD3_k127_6058755_2	925409.KI911562_gene816	1.031e-63	223.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1ISIF@117747|Sphingobacteriia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
HKD3_k127_6061541_2	700598.Niako_5003	5.801e-57	201.0	COG3538@1|root,COG3538@2|Bacteria,4NGY6@976|Bacteroidetes,1IP3P@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP028846	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
HKD3_k127_6061541_1	485917.Phep_0275	1.821e-73	253.0	COG2755@1|root,COG2755@2|Bacteria,4NHWJ@976|Bacteroidetes,1IS35@117747|Sphingobacteriia	976|Bacteroidetes	E	Lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_6061541_0	1267211.KI669560_gene2104	9.389e-82	279.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1IP91@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_606657_4	925409.KI911562_gene2963	1.414e-16	79.0	COG2308@1|root,COG2308@2|Bacteria,4NG4D@976|Bacteroidetes,1IRDC@117747|Sphingobacteriia	976|Bacteroidetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_606657_3	929713.NIASO_06090	3.927e-36	141.0	COG2940@1|root,COG2940@2|Bacteria,4P66M@976|Bacteroidetes,1IYW5@117747|Sphingobacteriia	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD3_k127_606657_0	700598.Niako_1212	3.733e-191	603.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HKD3_k127_606657_2	485917.Phep_3888	3.447e-63	226.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1IS2C@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD3_k127_606657_1	929556.Solca_0327	1.894e-137	446.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1IPH4@117747|Sphingobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	cap5D	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
HKD3_k127_6067795_2	1267211.KI669560_gene883	1.699e-58	211.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HKD3_k127_6067795_4	1123248.KB893322_gene579	2.484e-26	111.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1ITBU@117747|Sphingobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HKD3_k127_6067795_1	1123248.KB893331_gene3807	1.574e-58	213.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,1IT01@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD3_k127_6067795_3	700598.Niako_6237	3.45e-44	170.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,1IUI6@117747|Sphingobacteriia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6067795_0	1123248.KB893331_gene3786	1.895e-180	571.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1IQIK@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD3_k127_6081909_6	929713.NIASO_07760	1.169e-46	171.0	COG0607@1|root,COG0607@2|Bacteria,4P495@976|Bacteroidetes,1IYNV@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_6081909_5	1358423.N180_09130	5.613e-48	178.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1IS81@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_6081909_3	925409.KI911562_gene2100	1.016e-68	238.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1ISRY@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_6081909_4	509635.N824_07655	4.022e-59	213.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IWED@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
HKD3_k127_6081909_2	925409.KI911562_gene2099	4.207e-125	404.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes,1J1AE@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_6081909_7	700598.Niako_5625	2.156e-31	126.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1IZ3M@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_6081909_1	700598.Niako_2092	4.363e-158	505.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
HKD3_k127_6081909_0	925409.KI911562_gene2095	1.578e-159	512.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_6081909_8	700598.Niako_2564	5.467e-16	83.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,1ISMP@117747|Sphingobacteriia	976|Bacteroidetes	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD3_k127_6097876_7	925409.KI911562_gene782	3.715e-29	119.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,1IRWP@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD3_k127_6097876_1	925409.KI911562_gene434	5.315e-103	340.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IPNP@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
HKD3_k127_6097876_3	1380384.JADN01000004_gene1996	2.038e-45	166.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded DNA-binding protein	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_6097876_6	1123248.KB893386_gene1827	1.1e-38	147.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1ITN4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
HKD3_k127_6097876_4	1123248.KB893324_gene1729	7.896e-43	161.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
HKD3_k127_6097876_0	1122176.KB903532_gene2712	1.37e-134	438.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,1ISEJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001,PHP
HKD3_k127_6097876_8	887062.HGR_04803	9.566e-18	87.0	2E5Q2@1|root,330EP@2|Bacteria,1NCEJ@1224|Proteobacteria,2VVYT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
HKD3_k127_6097876_2	761193.Runsl_0168	4.042e-55	199.0	COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,47QDX@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	fecI	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD3_k127_6097876_5	925409.KI911562_gene816	1.365e-41	157.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1ISIF@117747|Sphingobacteriia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
HKD3_k127_6098349_1	1506583.JQJY01000003_gene3117	3.382e-43	174.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia,2P0VG@237|Flavobacterium	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
HKD3_k127_6098349_3	1500281.JQKZ01000015_gene2103	2.412e-33	146.0	COG4870@1|root,COG4870@2|Bacteria,4NS9R@976|Bacteroidetes,1I0EV@117743|Flavobacteriia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_C1
HKD3_k127_6098349_4	215803.DB30_4984	1.846e-13	83.0	COG1404@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3509@2|Bacteria,1Q2N6@1224|Proteobacteria,4388Y@68525|delta/epsilon subdivisions,2X3IJ@28221|Deltaproteobacteria,2YW8H@29|Myxococcales	28221|Deltaproteobacteria	OQ	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6098349_0	929703.KE386491_gene1543	8.286e-64	222.0	2CIH2@1|root,2ZTG0@2|Bacteria,4NNM2@976|Bacteroidetes,47VGE@768503|Cytophagia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
HKD3_k127_6098349_2	1121896.JMLU01000001_gene883	4.09e-36	142.0	COG4559@1|root,COG4559@2|Bacteria,4NK28@976|Bacteroidetes,1HXCE@117743|Flavobacteriia	976|Bacteroidetes	P	abc transporter (atp-binding protein)	hmuV	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HKD3_k127_6100855_2	925409.KI911562_gene488	9.536e-38	145.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6100855_3	1123248.KB893348_gene287	9.132e-35	141.0	COG5375@1|root,COG5375@2|Bacteria,4PNV6@976|Bacteroidetes,1J0U1@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
HKD3_k127_6100855_0	700598.Niako_6550	3.126e-160	509.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1IQIA@117747|Sphingobacteriia	976|Bacteroidetes	C	potassium channel beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_6100855_1	468059.AUHA01000003_gene1698	4.104e-60	219.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1IT3V@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,SusF_SusE,TPR_2
HKD3_k127_6101416_1	471854.Dfer_2354	2.806e-69	241.0	COG3279@1|root,COG3279@2|Bacteria,4NH5N@976|Bacteroidetes,47N4M@768503|Cytophagia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_6101416_0	1166018.FAES_1655	4.972e-213	690.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_6104399_4	700598.Niako_5791	2.075e-48	181.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1IPZD@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
HKD3_k127_6104399_3	1123248.KB893348_gene321	6.905e-68	233.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ISJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_6104399_0	925409.KI911562_gene1104	2.813e-164	528.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1IVGY@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_6104399_2	1123248.KB893348_gene82	1.433e-81	276.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6104399_1	925409.KI911562_gene1106	1.5e-84	286.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1IQ2V@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
HKD3_k127_6104399_5	504472.Slin_4697	5.005e-13	71.0	COG0607@1|root,COG1996@1|root,COG0607@2|Bacteria,COG1996@2|Bacteria,4PIDM@976|Bacteroidetes,47X19@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_6106630_2	459349.CLOAM1614	1.864e-06	56.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,FlgD_ig,Laminin_G_3
HKD3_k127_6106630_0	391596.PBAL39_25605	1.036e-260	836.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6106630_1	1492738.FEM21_26600	5.046e-34	142.0	COG2913@1|root,COG2913@2|Bacteria,4NGBM@976|Bacteroidetes,1I11Q@117743|Flavobacteriia,2P0WU@237|Flavobacterium	976|Bacteroidetes	J	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6120471_0	700598.Niako_6682	4.302e-240	747.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD3_k127_6120471_3	925409.KI911562_gene415	4.389e-70	248.0	COG1560@1|root,COG1560@2|Bacteria,4NPAI@976|Bacteroidetes,1J0BY@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HKD3_k127_6120471_2	700598.Niako_6678	1.73e-74	261.0	COG1560@1|root,COG1560@2|Bacteria,4NPAI@976|Bacteroidetes,1J0BY@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HKD3_k127_6120471_1	700598.Niako_6676	3.277e-200	632.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_6120471_4	700598.Niako_6675	2.683e-32	129.0	COG0640@1|root,COG0640@2|Bacteria,4NSHB@976|Bacteroidetes,1IZ28@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
HKD3_k127_6140161_0	1267211.KI669560_gene2035	5.145e-170	552.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1ISRU@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6143336_6	335543.Sfum_1251	4.563e-05	57.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
HKD3_k127_6143336_4	755732.Fluta_2084	3.437e-08	67.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
HKD3_k127_6143336_2	925409.KI911562_gene2303	2.241e-84	286.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1INT9@117747|Sphingobacteriia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD3_k127_6143336_5	1469557.JSWF01000014_gene2489	1.448e-06	59.0	COG5295@1|root,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1I2TY@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
HKD3_k127_6143336_0	700598.Niako_0985	7.238e-209	654.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_6143336_1	925409.KI911562_gene2299	1.94e-95	321.0	COG2316@1|root,COG2316@2|Bacteria,4NIAC@976|Bacteroidetes	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD3_k127_6143336_3	1239962.C943_02440	4.636e-27	112.0	COG3695@1|root,COG3695@2|Bacteria,4NZHS@976|Bacteroidetes	976|Bacteroidetes	L	enzyme binding	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
HKD3_k127_6144407_2	1123248.KB893348_gene324	1.029e-31	126.0	COG2972@1|root,COG2972@2|Bacteria,4NN11@976|Bacteroidetes,1IXVB@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_6144407_0	1123248.KB893348_gene325	5.716e-112	366.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1IX5E@117747|Sphingobacteriia	976|Bacteroidetes	K	Signal transduction response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_6144407_1	1123248.KB893348_gene293	1.597e-77	275.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_6154164_0	925409.KI911562_gene886	5.425e-117	380.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1IQ9A@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
HKD3_k127_6154164_3	700598.Niako_5762	4.774e-62	223.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6154164_1	1267211.KI669560_gene702	2.021e-88	304.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1INNS@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HKD3_k127_6154164_5	1218103.CIN01S_20_00310	3.949e-24	109.0	COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia,3ZNSA@59732|Chryseobacterium	976|Bacteroidetes	CO	Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
HKD3_k127_6154164_4	700598.Niako_5758	1.446e-38	155.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1ISX9@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD3_k127_6154164_2	925409.KI911562_gene1041	1.215e-75	258.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1IRYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, asnc family	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD3_k127_6154164_6	700598.Niako_6492	6.579e-08	54.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_6164825_1	1267211.KI669560_gene95	3.427e-57	203.0	COG1846@1|root,COG1846@2|Bacteria,4NSNN@976|Bacteroidetes,1ITUW@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD3_k127_6164825_0	1267211.KI669560_gene96	2.269e-304	941.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_6164825_2	1123248.KB893348_gene139	1.47e-44	163.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,1ITA6@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD3_k127_6170304_2	1267211.KI669560_gene1420	2.052e-31	125.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1IXEE@117747|Sphingobacteriia	976|Bacteroidetes	E	GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
HKD3_k127_6170304_3	761193.Runsl_4239	4.146e-09	64.0	2EG8H@1|root,335T3@2|Bacteria,4NW8Q@976|Bacteroidetes,47S7Q@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6170304_0	929713.NIASO_01615	3.991e-77	264.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,1ISX6@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
HKD3_k127_6170304_1	1123248.KB893321_gene559	1.659e-53	198.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,1IYJZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
HKD3_k127_6172078_1	1313421.JHBV01000029_gene1882	3.202e-11	73.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,MAM,PKD,P_proprotein,fn3
HKD3_k127_6172078_0	153721.MYP_1678	9.039e-14	80.0	COG4083@1|root,COG4083@2|Bacteria,4NM52@976|Bacteroidetes,47SA3@768503|Cytophagia	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	groEL	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
HKD3_k127_6172078_2	1123256.KB907925_gene1492	1.381e-10	62.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,1X9HN@135614|Xanthomonadales	135614|Xanthomonadales	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA
HKD3_k127_6182080_4	1122605.KB893625_gene1849	2.686e-23	99.0	COG0761@1|root,COG0761@2|Bacteria	2|Bacteria	IM	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
HKD3_k127_6182080_0	1123248.KB893337_gene2458	0.0	1332.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IX43@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
HKD3_k127_6182080_1	760192.Halhy_1321	2.333e-262	824.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1IVS2@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD3_k127_6182080_5	1530186.JQEY01000001_gene893	2.703e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD3_k127_6182080_3	1094466.KQS_09855	5.995e-25	109.0	COG2827@1|root,COG2827@2|Bacteria,4NUKY@976|Bacteroidetes,1II52@117743|Flavobacteriia,2NXVP@237|Flavobacterium	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD3_k127_6182080_2	938709.AUSH02000016_gene707	1.799e-29	121.0	COG1266@1|root,COG1266@2|Bacteria,4NTIG@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_6188605_0	1408813.AYMG01000003_gene2882	0.0	1131.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IP7Q@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_S41,Tricorn_C1
HKD3_k127_6198108_0	1267211.KI669560_gene2394	6.472e-316	980.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1INS9@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
HKD3_k127_6198108_1	700598.Niako_5069	5.408e-164	528.0	COG1858@1|root,COG1858@2|Bacteria,4NM2S@976|Bacteroidetes,1IVVD@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_6198108_2	1123248.KB893370_gene5091	1.336e-116	380.0	COG1793@1|root,COG1793@2|Bacteria,4NEKP@976|Bacteroidetes,1IQCK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
HKD3_k127_6205460_2	1453505.JASY01000002_gene2348	9.587e-80	277.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1I040@117743|Flavobacteriia,2NUS5@237|Flavobacterium	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HKD3_k127_6205460_0	1131812.JQMS01000001_gene927	1.282e-233	732.0	COG2308@1|root,COG2308@2|Bacteria,4NFMN@976|Bacteroidetes,1HXQ6@117743|Flavobacteriia,2NU8C@237|Flavobacterium	976|Bacteroidetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
HKD3_k127_6205460_1	1267211.KI669560_gene1278	2.157e-115	375.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HKD3_k127_6220900_4	1338011.BD94_2636	2.318e-45	169.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1I0Q4@117743|Flavobacteriia,34PWZ@308865|Elizabethkingia	976|Bacteroidetes	G	Lactonase, 7-bladed beta-propeller	pgl	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
HKD3_k127_6220900_0	700598.Niako_2651	2.248e-184	582.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
HKD3_k127_6220900_2	925409.KI911562_gene547	7.603e-172	549.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
HKD3_k127_6220900_3	1123248.KB893385_gene4846	3.79e-132	428.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1IP1D@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_6220900_1	700598.Niako_0114	7.999e-182	576.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
HKD3_k127_6223799_2	1123248.KB893316_gene4638	1.094e-36	141.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1IP9N@117747|Sphingobacteriia	976|Bacteroidetes	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
HKD3_k127_6223799_0	1267211.KI669560_gene1612	3.536e-95	316.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
HKD3_k127_6230793_0	1118054.CAGW01000063_gene2168	8.065e-91	308.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,271IU@186822|Paenibacillaceae	91061|Bacilli	P	Natural resistance-associated macrophage protein	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_6230793_1	925409.KI911562_gene742	5.629e-75	260.0	COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,1IP2K@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
HKD3_k127_6250070_2	700598.Niako_4454	1.832e-150	480.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1IPSN@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HKD3_k127_6250070_3	700598.Niako_4453	9.354e-60	210.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1ISBR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
HKD3_k127_6250070_0	925409.KI911562_gene2064	2.401e-259	806.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HKD3_k127_6250070_1	1267211.KI669560_gene1802	6.634e-229	724.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_6271627_3	761193.Runsl_1070	3.56e-23	100.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_6271627_2	1267211.KI669560_gene417	1.583e-56	201.0	2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6271627_1	471854.Dfer_2354	2.55e-75	261.0	COG3279@1|root,COG3279@2|Bacteria,4NH5N@976|Bacteroidetes,47N4M@768503|Cytophagia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_6271627_0	1185876.BN8_00055	8.26e-138	475.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_6282826_0	925409.KI911562_gene1427	6.667e-163	527.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
HKD3_k127_6282826_2	1267211.KI669560_gene1047	3.263e-83	283.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1IQPW@117747|Sphingobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HKD3_k127_6282826_1	1123248.KB893330_gene389	9.97e-115	371.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1INU0@117747|Sphingobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD3_k127_6303883_2	997884.HMPREF1068_01747	4.572e-86	292.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FNT8@200643|Bacteroidia,4ANGN@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_6303883_0	1166018.FAES_1634	1.19e-195	622.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_6303883_1	1120968.AUBX01000011_gene2998	3.203e-122	404.0	COG1435@1|root,COG1435@2|Bacteria,4NE0S@976|Bacteroidetes,47K26@768503|Cytophagia	976|Bacteroidetes	F	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6304259_2	1121912.AUHD01000007_gene490	2.122e-55	199.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HX4R@117743|Flavobacteriia	976|Bacteroidetes	P	arylsulfatase a	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_6304259_1	1089547.KB913013_gene2324	1.077e-149	484.0	COG1858@1|root,COG1858@2|Bacteria,4NJGU@976|Bacteroidetes,47NXP@768503|Cytophagia	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
HKD3_k127_6304259_0	485918.Cpin_1305	2e-323	998.0	COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD3_k127_6311326_1	643867.Ftrac_0812	4.908e-15	84.0	28MEF@1|root,2ZAS2@2|Bacteria,4NINI@976|Bacteroidetes,47S3F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6311326_0	1305737.JAFX01000001_gene128	9.748e-48	196.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47KYP@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
HKD3_k127_6314097_6	313606.M23134_02050	4.595e-35	139.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
HKD3_k127_6314097_5	1122605.KB893626_gene2588	2.493e-81	282.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,1IPDU@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
HKD3_k127_6314097_3	929713.NIASO_17165	1.868e-156	518.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1INPT@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
HKD3_k127_6314097_4	925409.KI911562_gene2972	2.507e-150	481.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1IP9F@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
HKD3_k127_6314097_2	1267211.KI669560_gene2092	4.828e-179	565.0	COG0189@1|root,COG0189@2|Bacteria,4NFK1@976|Bacteroidetes,1IR39@117747|Sphingobacteriia	976|Bacteroidetes	HJ	Glutathione synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6314097_1	925409.KI911562_gene1871	7.653e-196	617.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,1IRMY@117747|Sphingobacteriia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
HKD3_k127_6314097_0	1267211.KI669560_gene218	4.093e-235	732.0	COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1IPG4@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
HKD3_k127_6334795_5	1267211.KI669560_gene1238	3.734e-46	173.0	COG0629@1|root,COG0629@2|Bacteria,4PGRJ@976|Bacteroidetes,1IU5E@117747|Sphingobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
HKD3_k127_6334795_6	1185876.BN8_05223	7.175e-41	160.0	COG0737@1|root,COG0737@2|Bacteria,4NR6D@976|Bacteroidetes,47MWV@768503|Cytophagia	976|Bacteroidetes	F	5'-nucleotidase, C-terminal domain	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
HKD3_k127_6334795_2	1267211.KI669560_gene1240	2.537e-121	396.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IQB8@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD3_k127_6334795_0	1123248.KB893337_gene2332	1.388e-279	863.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1INXF@117747|Sphingobacteriia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD3_k127_6334795_7	491205.JARQ01000008_gene3793	3.578e-10	69.0	2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes,1I6S2@117743|Flavobacteriia,3ZRZV@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
HKD3_k127_6334795_3	1267211.KI669560_gene942	3.535e-112	375.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1INNI@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_6334795_4	1052684.PPM_0516	6.727e-48	179.0	COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,26UXR@186822|Paenibacillaceae	91061|Bacilli	GM	nucleoside-diphosphate sugar epimerase	M1-688	-	-	-	-	-	-	-	-	-	-	-	Epimerase,HIM1,NAD_binding_10
HKD3_k127_6334795_1	1134474.O59_003361	5.045e-127	415.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1FGGP@10|Cellvibrio	1236|Gammaproteobacteria	G	Glyco_18	chiA1	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,Glyco_hydro_18,fn3
HKD3_k127_6344492_3	1121957.ATVL01000012_gene770	2.152e-44	174.0	COG0702@1|root,COG0702@2|Bacteria,4NEDB@976|Bacteroidetes,47MB8@768503|Cytophagia	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6344492_4	536227.CcarbDRAFT_3134	4.289e-08	63.0	COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,24IBK@186801|Clostridia,36IS9@31979|Clostridiaceae	186801|Clostridia	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD3_k127_6344492_2	1288963.ADIS_3579	3.723e-225	729.0	COG1470@1|root,COG1470@2|Bacteria,4NF75@976|Bacteroidetes	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,CBM9_1,PEGA,Peptidase_S9
HKD3_k127_6344492_1	485918.Cpin_3541	5.654e-254	794.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1IPNJ@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_6344492_0	1185876.BN8_01204	9.666e-290	900.0	COG0578@1|root,COG0578@2|Bacteria,4PNA7@976|Bacteroidetes,47NR8@768503|Cytophagia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HKD3_k127_6345488_2	362418.IW19_17220	2.892e-23	108.0	2CJ7C@1|root,32ZYU@2|Bacteria,4NUT6@976|Bacteroidetes,1I538@117743|Flavobacteriia,2NV0V@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6345488_1	991.IW20_21620	2.802e-52	188.0	COG1246@1|root,COG1246@2|Bacteria,4PKDC@976|Bacteroidetes	976|Bacteroidetes	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
HKD3_k127_6345488_0	448385.sce2390	3.2e-56	209.0	COG0673@1|root,COG0673@2|Bacteria,1R7EF@1224|Proteobacteria	1224|Proteobacteria	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_6366157_3	925409.KI911562_gene2660	2.119e-59	212.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1IXEE@117747|Sphingobacteriia	976|Bacteroidetes	E	GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
HKD3_k127_6366157_2	925409.KI911562_gene2661	8.799e-102	339.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD3_k127_6366157_1	700598.Niako_1530	8.822e-104	342.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1IRFD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_6366157_5	765912.Thimo_2066	7.056e-11	69.0	2EI3W@1|root,33BVA@2|Bacteria,1NPW4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6366157_0	929713.NIASO_06770	6.17e-221	692.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD3_k127_6366157_4	925409.KI911562_gene2665	1.679e-31	133.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
HKD3_k127_6366572_2	1358423.N180_01705	2.939e-54	198.0	COG0346@1|root,COG0346@2|Bacteria,4NQSP@976|Bacteroidetes,1ITSY@117747|Sphingobacteriia	976|Bacteroidetes	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_6366572_1	1120965.AUBV01000005_gene1764	8.831e-190	608.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes	976|Bacteroidetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_6366572_0	700598.Niako_5603	1.929e-227	712.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1IQYP@117747|Sphingobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD3_k127_6378038_2	861299.J421_1115	5.66e-07	54.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6378038_1	1123248.KB893319_gene4046	2.57e-14	79.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1IQH4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
HKD3_k127_6378038_0	700598.Niako_5782	1.434e-103	353.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1IQH4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
HKD3_k127_6387145_3	700598.Niako_0108	1.417e-24	104.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1IP8F@117747|Sphingobacteriia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD3_k127_6387145_0	925409.KI911562_gene1981	1.523e-249	777.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1IPJB@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HKD3_k127_6387145_1	1123248.KB893385_gene4854	3.43e-235	734.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1IPB8@117747|Sphingobacteriia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HKD3_k127_6387145_2	1123248.KB893385_gene4853	2.115e-100	338.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1IRCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
HKD3_k127_6388491_1	1279017.AQYJ01000026_gene259	8.64e-10	64.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K03932	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	CE1,GH5,GH9	-	CBM_2,CBM_4_9,Cellulase,Glyco_hydro_16,PSCyt3,PSD3,PSD4,PSD5,RicinB_lectin_2,YceI
HKD3_k127_6388491_0	742766.HMPREF9455_03453	5.648e-157	507.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FNT8@200643|Bacteroidia,22WE2@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_639625_0	925409.KI911562_gene2784	3.759e-266	829.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1IQDQ@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD3_k127_639625_2	1123248.KB893337_gene2337	3.461e-32	134.0	COG3637@1|root,COG3637@2|Bacteria,4NWNN@976|Bacteroidetes,1J0D5@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_639625_1	929713.NIASO_12095	3.031e-141	454.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1IPSC@117747|Sphingobacteriia	976|Bacteroidetes	S	DNA mismatch repair protein MutT	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HKD3_k127_6397713_3	925409.KI911562_gene1046	1.269e-82	281.0	COG0860@1|root,COG0860@2|Bacteria,4NH6Q@976|Bacteroidetes	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
HKD3_k127_6397713_0	1121481.AUAS01000001_gene4757	4.927e-216	677.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47KCX@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD3_k127_6397713_4	468059.AUHA01000002_gene288	6.241e-07	59.0	2E9XE@1|root,33436@2|Bacteria,4NV30@976|Bacteroidetes,1IZEA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6397713_1	925409.KI911562_gene838	2.474e-195	614.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes	976|Bacteroidetes	C	alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
HKD3_k127_6397713_2	761193.Runsl_5621	6.949e-123	403.0	COG0151@1|root,COG0151@2|Bacteria,4P144@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6398179_2	1250006.JHZZ01000001_gene372	3.002e-05	48.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia,3VX8I@52959|Polaribacter	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_6398179_1	925409.KI911562_gene679	2.021e-71	246.0	COG2207@1|root,COG2207@2|Bacteria,4NS41@976|Bacteroidetes,1J0BF@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_6398179_0	925409.KI911562_gene2716	8.155e-298	918.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1IP50@117747|Sphingobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HKD3_k127_6400467_1	485918.Cpin_1945	1.31e-197	632.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD3_k127_6400467_4	700598.Niako_7362	8.387e-24	109.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1IUCJ@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Phosphoesterase, HXTX	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_6400467_0	1123248.KB893314_gene3650	1.348e-255	795.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HKD3_k127_6400467_2	925409.KI911562_gene2239	1.246e-181	571.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HKD3_k127_6400467_3	1122605.KB893647_gene496	1.871e-54	194.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HKD3_k127_6405989_2	700598.Niako_1886	1.513e-51	184.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1IQ62@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD3_k127_6405989_0	700598.Niako_1887	4.98e-87	298.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1IRW5@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HKD3_k127_6405989_1	929556.Solca_2421	2.897e-86	290.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD3_k127_6411203_1	1123248.KB893386_gene1871	8.184e-66	233.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,1IP2M@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
HKD3_k127_6411203_0	1267211.KI669560_gene2365	4.931e-91	304.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1IS2H@117747|Sphingobacteriia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
HKD3_k127_6411203_2	1267211.KI669560_gene2364	2.885e-06	58.0	2EKSY@1|root,33EGP@2|Bacteria,4NXJC@976|Bacteroidetes	976|Bacteroidetes	S	COG NOG23390 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6414242_1	925409.KI911562_gene1368	2.615e-186	588.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1IW5I@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
HKD3_k127_6414242_0	929556.Solca_0314	8.007e-211	666.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQK1@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_6419888_2	700598.Niako_4053	1.329e-42	164.0	COG5263@1|root,COG5263@2|Bacteria,4PN8Y@976|Bacteroidetes,1J0PQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
HKD3_k127_6419888_3	1123248.KB893329_gene4481	3.515e-41	156.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IS84@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HKD3_k127_6419888_0	1267211.KI669560_gene1183	4.162e-127	413.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1INNA@117747|Sphingobacteriia	976|Bacteroidetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD3_k127_6419888_4	700598.Niako_7317	1.748e-26	113.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,1ITPF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6419888_1	1123248.KB893329_gene4484	4.665e-83	282.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD3_k127_6420288_1	700598.Niako_7219	1.835e-16	80.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQWT@117747|Sphingobacteriia	976|Bacteroidetes	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
HKD3_k127_6420288_0	700598.Niako_7220	5.671e-201	636.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IR24@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HKD3_k127_6420288_2	700598.Niako_7221	3.419e-11	66.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HKD3_k127_6420470_0	700598.Niako_5805	4.95e-280	878.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_6420470_2	504472.Slin_1929	4.367e-45	169.0	COG0607@1|root,COG0607@2|Bacteria,4NR99@976|Bacteroidetes,47SFJ@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6420470_1	1239962.C943_04627	7.693e-85	288.0	COG3000@1|root,COG3000@2|Bacteria,4NMKR@976|Bacteroidetes,47PJ4@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_6420470_3	929713.NIASO_15950	4.108e-14	77.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1IQIK@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD3_k127_6425607_2	1341181.FLJC2902T_24050	1.149e-49	179.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,1HWT3@117743|Flavobacteriia,2NSBP@237|Flavobacterium	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
HKD3_k127_6425607_0	688270.Celal_4232	1.044e-136	445.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes,1I2DH@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
HKD3_k127_6425607_1	1202532.FF52_18215	1.385e-90	305.0	COG2067@1|root,COG2067@2|Bacteria,4NQHN@976|Bacteroidetes,1I6SN@117743|Flavobacteriia,2NVGV@237|Flavobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_6446835_0	761193.Runsl_0533	7.65e-249	773.0	COG1350@1|root,COG1350@2|Bacteria,4PKSY@976|Bacteroidetes,47NFK@768503|Cytophagia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_6446835_1	1267211.KI669560_gene2678	2.388e-144	462.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1IRN3@117747|Sphingobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
HKD3_k127_644946_1	929703.KE386491_gene2608	1.301e-37	141.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,47JEZ@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
HKD3_k127_644946_0	153721.MYP_4380	4.064e-175	555.0	COG2141@1|root,COG2141@2|Bacteria,4NHGI@976|Bacteroidetes,47MJ4@768503|Cytophagia	976|Bacteroidetes	C	Luciferase-like monooxygenase	yhbW	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_6449883_3	1267211.KI669560_gene1565	8.302e-65	224.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1ISJ9@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
HKD3_k127_6449883_5	700598.Niako_2172	1.071e-13	73.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_6449883_0	1123248.KB893385_gene4740	5.206e-145	474.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_6449883_2	925409.KI911562_gene2283	4.041e-70	246.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_6449883_1	700598.Niako_1050	2.122e-81	303.0	COG1520@1|root,COG4935@1|root,COG1520@2|Bacteria,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes,1IYMI@117747|Sphingobacteriia	976|Bacteroidetes	O	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6482839_2	1123248.KB893314_gene3570	2.956e-70	245.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1IRTC@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD3_k127_6482839_3	700598.Niako_0179	4.616e-61	216.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1INUM@117747|Sphingobacteriia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD3_k127_6482839_1	485918.Cpin_1533	2.225e-92	305.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1INUM@117747|Sphingobacteriia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD3_k127_6482839_0	760192.Halhy_4416	1.762e-94	320.0	COG2311@1|root,COG2311@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD3_k127_6494967_1	1408813.AYMG01000028_gene2493	1.069e-128	415.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,1IREZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_6494967_0	1123248.KB893319_gene3990	3.668e-190	597.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1IQDJ@117747|Sphingobacteriia	976|Bacteroidetes	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
HKD3_k127_6494967_4	925409.KI911562_gene914	7.964e-40	152.0	COG4654@1|root,COG4654@2|Bacteria,4NSJC@976|Bacteroidetes,1ITX4@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_6494967_2	1279009.ADICEAN_02474	1.438e-85	289.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,47NE6@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_6494967_3	880070.Cycma_2650	5.128e-46	170.0	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,47QYN@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
HKD3_k127_6494967_5	1168289.AJKI01000002_gene2346	7.812e-39	149.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,2FM0Q@200643|Bacteroidia,3XKH3@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
HKD3_k127_6504943_0	1122605.KB893630_gene3980	1.024e-108	360.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1IP76@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_6504943_2	509635.N824_15510	5.38e-28	124.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1ITQK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6504943_1	925409.KI911562_gene2864	3.77e-55	198.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1IRX6@117747|Sphingobacteriia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
HKD3_k127_6541507_1	760192.Halhy_2813	2.729e-42	158.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1IS1P@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD3_k127_6541507_0	714943.Mucpa_5141	2.242e-111	366.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1IQXC@117747|Sphingobacteriia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
HKD3_k127_6541507_2	1150600.ADIARSV_1051	1.428e-21	94.0	COG2334@1|root,COG2334@2|Bacteria,4NITA@976|Bacteroidetes,1IRG4@117747|Sphingobacteriia	976|Bacteroidetes	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6548247_0	1550091.JROE01000005_gene2110	1.331e-171	545.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,1IW7F@117747|Sphingobacteriia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_6548247_2	388413.ALPR1_17868	5.897e-86	290.0	COG2755@1|root,COG2755@2|Bacteria,4NM4Z@976|Bacteroidetes,47PMF@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_6548247_1	1349822.NSB1T_05035	1.275e-134	443.0	COG1196@1|root,COG2755@1|root,COG1196@2|Bacteria,COG2755@2|Bacteria,4PN43@976|Bacteroidetes,2G0PM@200643|Bacteroidia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6548247_3	1396.DJ87_1753	1.079e-61	226.0	COG1554@1|root,COG3250@1|root,COG1554@2|Bacteria,COG3250@2|Bacteria,1TPKN@1239|Firmicutes,4HCCF@91061|Bacilli,1ZAWT@1386|Bacillus	91061|Bacilli	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Gram_pos_anchor,YSIRK_signal
HKD3_k127_6558120_2	1123248.KB893315_gene3175	9.786e-100	328.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD3_k127_6558120_1	1122605.KB893627_gene2879	4.179e-118	384.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HKD3_k127_6558120_0	700598.Niako_4423	1.558e-214	674.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_6558120_4	925409.KI911562_gene2150	1.154e-43	162.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1ITHB@117747|Sphingobacteriia	976|Bacteroidetes	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
HKD3_k127_6558120_3	925409.KI911562_gene2149	1.133e-62	221.0	COG2910@1|root,COG2910@2|Bacteria,4PP94@976|Bacteroidetes,1IYBJ@117747|Sphingobacteriia	976|Bacteroidetes	S	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
HKD3_k127_6566801_2	1122605.KB893638_gene3443	8.819e-40	153.0	COG1082@1|root,COG1082@2|Bacteria,4NJF7@976|Bacteroidetes,1ISEM@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD3_k127_6566801_1	929713.NIASO_00860	3.713e-41	157.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_6566801_0	1122605.KB893625_gene1794	6.604e-192	607.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
HKD3_k127_6584698_1	1454007.JAUG01000043_gene7	2.628e-84	284.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NZSK@976|Bacteroidetes,1IW3X@117747|Sphingobacteriia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6584698_0	700598.Niako_3086	7.227e-152	494.0	COG3193@1|root,COG3193@2|Bacteria,4PNUR@976|Bacteroidetes,1J0SV@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6584698_2	700598.Niako_3085	1.333e-51	193.0	2DVZ7@1|root,33XT0@2|Bacteria,4P305@976|Bacteroidetes,1IXZF@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4843)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4843
HKD3_k127_6584698_3	700598.Niako_3084	2.418e-07	56.0	2DV0V@1|root,33TES@2|Bacteria,4P1AE@976|Bacteroidetes,1IWVT@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD-like family	-	-	-	-	-	-	-	-	-	-	-	-	PKD_2
HKD3_k127_6609714_1	865937.Gilli_0778	5.053e-55	197.0	COG4319@1|root,COG4319@2|Bacteria,4PAP3@976|Bacteroidetes,1I8VA@117743|Flavobacteriia,2P7PQ@244698|Gillisia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_6609714_0	504472.Slin_3905	4.047e-64	223.0	COG0251@1|root,COG0251@2|Bacteria,4NMXE@976|Bacteroidetes,47QXM@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HKD3_k127_6609714_3	1121931.AUHG01000010_gene706	2.275e-27	119.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
HKD3_k127_6623376_3	760192.Halhy_2651	2.915e-17	85.0	COG0454@1|root,COG0456@2|Bacteria,4NQSN@976|Bacteroidetes,1ITBC@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_6623376_0	1123248.KB893319_gene4058	0.0	1153.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD3_k127_6623376_2	471854.Dfer_5030	5.348e-78	274.0	COG1929@1|root,COG1929@2|Bacteria,4NFK8@976|Bacteroidetes,47MW7@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
HKD3_k127_6623376_1	1122176.KB903538_gene1517	3.08e-85	290.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_6627060_1	700598.Niako_5810	2.395e-58	210.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,1IRUG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
HKD3_k127_6627060_2	925409.KI911562_gene575	3.644e-49	182.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_6627060_0	1123248.KB893314_gene3423	1.39e-97	336.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_6627571_1	1267211.KI669560_gene730	3.71e-87	289.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,1IRA1@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD3_k127_6627571_4	1150600.ADIARSV_1967	1.739e-05	54.0	2E5JG@1|root,330AS@2|Bacteria,4NWYV@976|Bacteroidetes,1ITWB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6627571_2	700598.Niako_6461	1.466e-72	261.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6627571_0	700598.Niako_5811	2.032e-127	426.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
HKD3_k127_6627571_3	1123248.KB893348_gene138	3.557e-66	229.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1IP7N@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD3_k127_6635004_1	1267211.KI669560_gene40	2.624e-219	694.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1IQCU@117747|Sphingobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD3_k127_6635004_0	1123057.P872_07965	3.021e-282	899.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47MXX@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_6638127_1	700598.Niako_1547	7.498e-153	486.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1INM8@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HKD3_k127_6638127_0	1267211.KI669560_gene2291	6.76e-162	523.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6648303_0	1123248.KB893318_gene4191	2.158e-149	483.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1IPU7@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HKD3_k127_6648303_2	471854.Dfer_3974	1.578e-11	70.0	2E8WY@1|root,33373@2|Bacteria,4NV40@976|Bacteroidetes,47RXW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6648303_1	929556.Solca_4460	9.244e-96	327.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1IPAV@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_6654607_2	485918.Cpin_1724	7.873e-31	126.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_4
HKD3_k127_6654607_0	925409.KI911562_gene1560	1.685e-238	750.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD3_k127_6654607_1	1267211.KI669560_gene2472	8.052e-135	436.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_6656218_3	525373.HMPREF0766_11428	1.721e-81	274.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1IPSJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase, class I	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_6656218_1	925409.KI911562_gene2797	1.092e-114	375.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1IPH1@117747|Sphingobacteriia	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
HKD3_k127_6656218_0	925409.KI911562_gene2796	3.835e-262	816.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD3_k127_6656218_2	700598.Niako_4507	4.163e-85	283.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD3_k127_666070_4	1123248.KB893337_gene2343	2.064e-50	184.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HKD3_k127_666070_5	925409.KI911562_gene2949	1.723e-34	141.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1ITDS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_666070_1	925409.KI911562_gene2948	1.837e-134	434.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1IPCV@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD3_k127_666070_0	925409.KI911562_gene2947	1.003e-139	447.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1IQ5V@117747|Sphingobacteriia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD3_k127_666070_3	700598.Niako_1145	2.809e-94	313.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
HKD3_k127_666070_2	1123248.KB893337_gene2338	1.33e-101	341.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1IPSC@117747|Sphingobacteriia	976|Bacteroidetes	S	DNA mismatch repair protein MutT	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HKD3_k127_6673709_3	471854.Dfer_3315	3.483e-68	237.0	COG1629@1|root,COG4771@2|Bacteria,4PMEH@976|Bacteroidetes,47Y35@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
HKD3_k127_6673709_0	1267211.KI669560_gene1404	4.321e-264	820.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_6673709_1	1123248.KB893326_gene1473	1.84e-159	520.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1IV25@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_6673709_4	762903.Pedsa_2925	9.838e-46	171.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1ISTP@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_6673709_5	1237149.C900_00166	7.072e-30	132.0	COG1044@1|root,COG1044@2|Bacteria,4NQJ1@976|Bacteroidetes	976|Bacteroidetes	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6673709_2	1296415.JACC01000037_gene1112	2.146e-93	333.0	COG3534@1|root,COG3979@1|root,COG4447@1|root,COG5295@1|root,COG3534@2|Bacteria,COG3979@2|Bacteria,COG4447@2|Bacteria,COG5295@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2YM66@290174|Aquimarina	976|Bacteroidetes	UW	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
HKD3_k127_668553_1	925409.KI911562_gene1620	1.05e-53	197.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
HKD3_k127_668553_0	925409.KI911562_gene1619	9.929e-259	807.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HKD3_k127_6693228_9	925409.KI911562_gene2669	7.019e-32	131.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_6693228_6	1267211.KI669560_gene1411	4.402e-64	224.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,1ISYY@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
HKD3_k127_6693228_0	1123248.KB893319_gene3985	3.865e-291	911.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD3_k127_6693228_4	925409.KI911562_gene2672	8.837e-128	414.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1IQKP@117747|Sphingobacteriia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD3_k127_6693228_3	700598.Niako_2585	5.433e-141	451.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1IRN1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HKD3_k127_6693228_10	1198452.Jab_2c06530	8.91e-19	87.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6693228_5	1408813.AYMG01000025_gene2654	5.498e-66	230.0	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,1ISGY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
HKD3_k127_6693228_7	1341181.FLJC2902T_20750	2.212e-54	193.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia,2NW84@237|Flavobacterium	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_6693228_8	485918.Cpin_3648	4.26e-41	155.0	COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,1IQ7I@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_6693228_1	700598.Niako_4495	2.274e-157	507.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1IQE3@117747|Sphingobacteriia	976|Bacteroidetes	G	sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
HKD3_k127_6693228_2	1123248.KB893317_gene4296	1.607e-151	491.0	COG1629@1|root,COG4771@2|Bacteria,4PMEH@976|Bacteroidetes,1J0ZJ@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
HKD3_k127_6712496_0	700598.Niako_6795	0.0	1072.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1IPPB@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17
HKD3_k127_6712496_2	700598.Niako_2485	2.598e-71	248.0	2DWQN@1|root,341FB@2|Bacteria,4P4AQ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF3575)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
HKD3_k127_6712496_1	700598.Niako_6283	2.155e-90	307.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1IXIZ@117747|Sphingobacteriia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
HKD3_k127_6727180_0	925409.KI911562_gene2965	6.06e-194	622.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1IQ6E@117747|Sphingobacteriia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
HKD3_k127_6727180_3	1123248.KB893323_gene1562	5.058e-112	375.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,1IRY1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD3_k127_6727180_7	1189612.A33Q_3426	3.31e-62	220.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD3_k127_6727180_1	509635.N824_25495	4.522e-128	424.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1INWC@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD3_k127_6727180_8	1336803.PHEL49_1366	8.248e-34	134.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6727180_4	1123248.KB893326_gene1479	2.524e-99	332.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1IP8N@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
HKD3_k127_6727180_2	1408433.JHXV01000007_gene2859	2.664e-119	391.0	COG2267@1|root,COG2267@2|Bacteria,4PI0F@976|Bacteroidetes,1IG41@117743|Flavobacteriia,2PC11@246874|Cryomorphaceae	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
HKD3_k127_6727180_6	388413.ALPR1_15864	7.691e-85	294.0	COG5571@1|root,COG5571@2|Bacteria,4NMTM@976|Bacteroidetes,47UPX@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
HKD3_k127_6727180_5	1454010.JEOE01000001_gene829	4.769e-86	292.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4,GATase_6
HKD3_k127_6727180_9	700598.Niako_4351	2.242e-30	129.0	COG0484@1|root,COG0484@2|Bacteria,4P77W@976|Bacteroidetes	976|Bacteroidetes	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
HKD3_k127_6729392_0	1123248.KB893326_gene1293	0.0	1425.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_6729392_1	1267211.KI669560_gene1251	4.047e-187	596.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1IPDB@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD3_k127_6729757_4	1123248.KB893381_gene1099	8.562e-112	366.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD3_k127_6729757_7	700598.Niako_5589	1.084e-64	229.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1INQF@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HKD3_k127_6729757_5	700598.Niako_5588	1.715e-104	346.0	COG0861@1|root,COG0861@2|Bacteria,4NH6F@976|Bacteroidetes,1J0BP@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
HKD3_k127_6729757_3	700598.Niako_5587	7.259e-129	420.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD3_k127_6729757_1	925409.KI911562_gene284	3.813e-203	637.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1INYF@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_6729757_2	925409.KI911562_gene2326	7.005e-158	516.0	COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,1IW8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
HKD3_k127_6729757_0	925409.KI911562_gene2325	0.0	1195.0	COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1IW0D@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6729757_6	485918.Cpin_0879	7.778e-95	317.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1IRD0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HKD3_k127_6733482_2	1506583.JQJY01000001_gene398	2.424e-05	55.0	COG5295@1|root,COG5295@2|Bacteria,4NR12@976|Bacteroidetes,1IKK1@117743|Flavobacteriia,2P0QJ@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6733482_0	925409.KI911562_gene3000	6.507e-206	649.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,1INTU@117747|Sphingobacteriia	976|Bacteroidetes	J	PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HKD3_k127_6733482_1	1124780.ANNU01000032_gene1208	3.234e-57	204.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,47KUW@768503|Cytophagia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
HKD3_k127_6743392_1	1122621.ATZA01000042_gene1866	6.571e-52	188.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_6743392_0	1239962.C943_00387	3.766e-69	247.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47TMG@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_6761611_0	700598.Niako_5757	4.945e-154	488.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_6761611_1	755732.Fluta_2111	1.449e-23	111.0	COG0590@1|root,COG0590@2|Bacteria,4PK77@976|Bacteroidetes,1IEUU@117743|Flavobacteriia,2PBS8@246874|Cryomorphaceae	976|Bacteroidetes	FJ	tRNA wobble adenosine to inosine editing	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6770931_3	929556.Solca_4167	2.75e-48	174.0	COG1011@1|root,COG1011@2|Bacteria,4NF0Y@976|Bacteroidetes,1IRE7@117747|Sphingobacteriia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
HKD3_k127_6770931_1	1123248.KB893315_gene3004	2.817e-147	479.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1IR1T@117747|Sphingobacteriia	976|Bacteroidetes	CP	ABC-type Na efflux pump, permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD3_k127_6770931_2	1123248.KB893315_gene3005	1.454e-139	449.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1IQ0E@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD3_k127_6770931_0	700598.Niako_7366	4.273e-216	682.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1IQIE@117747|Sphingobacteriia	976|Bacteroidetes	S	FAD-dependent dehydrogenase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
HKD3_k127_6778955_2	1229487.AMYW01000002_gene1505	5.747e-10	64.0	2E6Q3@1|root,331AC@2|Bacteria,4NUP2@976|Bacteroidetes,1I4Z6@117743|Flavobacteriia,2NWBJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5362
HKD3_k127_6778955_0	925409.KI911562_gene1794	3.379e-277	856.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1IQ4M@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HKD3_k127_6778955_1	925409.KI911562_gene1793	7.389e-17	84.0	296FN@1|root,2ZTR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6787424_0	925409.KI911562_gene1982	0.0	2406.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1IP8F@117747|Sphingobacteriia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD3_k127_6788620_1	700598.Niako_0554	3.246e-66	229.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1ITHC@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
HKD3_k127_6788620_0	1123248.KB893314_gene3275	7.548e-111	369.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HKD3_k127_6788620_2	743722.Sph21_3735	3.007e-14	74.0	COG1977@1|root,COG1977@2|Bacteria,4PGWN@976|Bacteroidetes,1IUJJ@117747|Sphingobacteriia	976|Bacteroidetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD3_k127_6794753_2	925409.KI911562_gene1215	1.869e-88	295.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_6794753_0	1123248.KB893317_gene4379	7.598e-150	490.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD3_k127_6794753_1	1122605.KB893646_gene227	2.199e-113	372.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD3_k127_6794753_4	700598.Niako_6937	8.889e-23	100.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1IUJM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
HKD3_k127_6794753_3	700598.Niako_6938	2.458e-34	134.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1INNN@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD3_k127_6798887_3	1120965.AUBV01000006_gene2189	9.898e-17	83.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6798887_1	700598.Niako_4252	1.45e-27	120.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1IT9I@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_6798887_2	1089547.KB913013_gene1290	1.883e-24	104.0	2ADIU@1|root,31396@2|Bacteria,4NW8B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6798887_0	421531.IX38_21775	6.951e-39	155.0	COG0454@1|root,COG0456@2|Bacteria,4NKGU@976|Bacteroidetes,1HZFA@117743|Flavobacteriia,3ZRA7@59732|Chryseobacterium	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_6802269_1	1157490.EL26_05245	0.0001684	50.0	COG1404@1|root,COG1572@1|root,COG3227@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli	91061|Bacilli	E	COG3227 Zinc metalloprotease (elastase)	mpl	GO:0005575,GO:0005576	3.4.24.28,3.4.24.29	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
HKD3_k127_6802269_0	1123248.KB893330_gene430	2.543e-78	263.0	COG0300@1|root,COG0300@2|Bacteria,4PKC5@976|Bacteroidetes,1J0KE@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
HKD3_k127_6802472_2	925409.KI911562_gene2995	1.822e-29	119.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,4NDUW@976|Bacteroidetes,1IQ7T@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
HKD3_k127_6802472_1	700598.Niako_5275	2.414e-123	400.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1IP3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
HKD3_k127_6802472_0	700598.Niako_5277	5.811e-162	518.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1IPZM@117747|Sphingobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HKD3_k127_6814831_1	925409.KI911562_gene2185	9.55e-10	61.0	COG3055@1|root,COG3391@1|root,COG4935@1|root,COG3055@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4PMIF@976|Bacteroidetes	976|Bacteroidetes	E	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Laminin_G_3
HKD3_k127_6814831_0	700598.Niako_6871	1.282e-136	444.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1IVXW@117747|Sphingobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
HKD3_k127_6814831_2	485918.Cpin_3523	5.706e-09	59.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD3_k127_682904_2	485917.Phep_2386	1.071e-16	81.0	COG0262@1|root,COG0262@2|Bacteria,4NPM3@976|Bacteroidetes,1IT7M@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HKD3_k127_682904_1	558152.IQ37_17995	1.016e-37	146.0	COG5485@1|root,COG5485@2|Bacteria,4NQC7@976|Bacteroidetes,1IAJB@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
HKD3_k127_682904_0	485918.Cpin_4679	7.013e-46	177.0	COG2207@1|root,COG2207@2|Bacteria,4NF81@976|Bacteroidetes,1IS1N@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator araC	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18,HTH_AraC
HKD3_k127_6849063_3	1121288.AULL01000013_gene1729	0.000156	51.0	2EYBD@1|root,33RJS@2|Bacteria,4P0E2@976|Bacteroidetes,1I82U@117743|Flavobacteriia,3ZPVZ@59732|Chryseobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
HKD3_k127_6849063_2	1267211.KI669560_gene1791	8.086e-62	215.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
HKD3_k127_6849063_1	1305737.JAFX01000001_gene2862	6.113e-72	250.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,47PET@768503|Cytophagia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HKD3_k127_6849063_0	700598.Niako_2028	1.946e-106	349.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1IPJX@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
HKD3_k127_686388_3	558169.AGAV01000003_gene2655	6.113e-05	49.0	2EIAV@1|root,33C29@2|Bacteria,1VMAE@1239|Firmicutes,4HRG9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_686388_0	700598.Niako_5147	1.953e-191	600.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IUYE@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_686388_1	700598.Niako_5146	2.37e-43	159.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HKD3_k127_6878391_0	865937.Gilli_0666	1.088e-110	369.0	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,1HXBG@117743|Flavobacteriia,2P68E@244698|Gillisia	976|Bacteroidetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
HKD3_k127_6878391_1	1237149.C900_03594	1.837e-92	314.0	COG0726@1|root,COG0726@2|Bacteria,4NK5Y@976|Bacteroidetes,47PCK@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_6878391_2	1237149.C900_03593	0.0001944	45.0	2DBB7@1|root,2Z85R@2|Bacteria,4NJNG@976|Bacteroidetes,47RTY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6885258_2	760192.Halhy_4118	2.276e-43	162.0	COG3876@1|root,COG3876@2|Bacteria,4NKHR@976|Bacteroidetes,1IWXE@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HKD3_k127_6885258_4	1123248.KB893348_gene112	2.581e-12	75.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_6885258_3	700598.Niako_6727	1.152e-28	123.0	COG1514@1|root,COG1514@2|Bacteria,4NX5U@976|Bacteroidetes,1IYZ5@117747|Sphingobacteriia	976|Bacteroidetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_6885258_0	925409.KI911562_gene1118	7.731e-156	498.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1IPD6@117747|Sphingobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_6885258_1	1122621.ATZA01000002_gene1564	3.783e-121	400.0	COG2908@1|root,COG2908@2|Bacteria,4PNWQ@976|Bacteroidetes,1J0UM@117747|Sphingobacteriia	976|Bacteroidetes	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
HKD3_k127_6885258_5	709991.Odosp_1604	7.369e-11	67.0	COG3187@1|root,COG3187@2|Bacteria,4NRFE@976|Bacteroidetes,2FQEM@200643|Bacteroidia	976|Bacteroidetes	O	COG3187 Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	META
HKD3_k127_6901964_1	925409.KI911562_gene1990	1.266e-74	261.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_6901964_0	1267211.KI669560_gene2091	1.681e-84	287.0	COG2382@1|root,COG2382@2|Bacteria,4NI86@976|Bacteroidetes,1IQ5J@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_6918362_2	700598.Niako_6017	9.131e-97	319.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1INZ4@117747|Sphingobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HKD3_k127_6918362_1	700598.Niako_6018	3.469e-172	545.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HKD3_k127_6918362_3	555779.Dthio_PD0422	6.013e-57	203.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
HKD3_k127_6918362_0	925409.KI911562_gene473	5.133e-202	632.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1J0KU@117747|Sphingobacteriia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
HKD3_k127_6946450_2	700598.Niako_4930	3.71e-36	144.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,1IU3T@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane chaperone Skp	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_6946450_0	1123248.KB893314_gene3387	0.0	1083.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPAB@117747|Sphingobacteriia	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
HKD3_k127_6946450_3	929713.NIASO_18845	2.401e-32	130.0	COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes	976|Bacteroidetes	S	RNA-binding protein	ykfA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD3_k127_6946450_1	1267211.KI669560_gene1169	1.031e-124	403.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD3_k127_6979797_0	929562.Emtol_1487	6.506e-41	158.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_6979797_1	1237149.C900_05169	1.582e-25	115.0	COG3548@1|root,COG3548@2|Bacteria,4NW8Z@976|Bacteroidetes,47V92@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD3_k127_6989423_1	485918.Cpin_3971	3.376e-68	238.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1IR44@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HKD3_k127_6989423_0	925409.KI911562_gene274	2.46e-253	795.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1IPWE@117747|Sphingobacteriia	976|Bacteroidetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
HKD3_k127_6989423_2	86416.Clopa_2105	2.876e-33	134.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,36JND@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
HKD3_k127_7001901_2	926556.Echvi_4050	3.982e-41	161.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,47JB6@768503|Cytophagia	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
HKD3_k127_7001901_0	1267211.KI669560_gene72	7.76e-227	707.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_7001901_1	592029.DDD_0451	2.632e-122	400.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
HKD3_k127_703216_0	938709.AUSH02000073_gene1679	1.297e-188	594.0	COG1914@1|root,COG1914@2|Bacteria,4NDZ1@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_703216_3	700598.Niako_1684	1.14e-31	128.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,1J144@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD3_k127_703216_2	1123234.AUKI01000020_gene664	3.122e-69	245.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,1I391@117743|Flavobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD3_k127_703216_1	485918.Cpin_0408	3.807e-104	349.0	COG3291@1|root,COG3291@2|Bacteria,4NQ3X@976|Bacteroidetes,1IXCU@117747|Sphingobacteriia	976|Bacteroidetes	M	Legume lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Lectin_legB,PKD
HKD3_k127_7036320_0	1218108.KB908292_gene1473	2.287e-213	676.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
HKD3_k127_7041690_2	925409.KI911562_gene1608	1.967e-106	359.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
HKD3_k127_7041690_1	1123248.KB893385_gene4802	3.812e-193	609.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD3_k127_7041690_3	700598.Niako_5503	1.016e-67	234.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1ISPN@117747|Sphingobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HKD3_k127_7041690_0	485918.Cpin_3586	0.0	1031.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,1IPRU@117747|Sphingobacteriia	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_7041690_5	1121904.ARBP01000001_gene5914	5.878e-21	108.0	COG4249@1|root,COG4249@2|Bacteria,4NH9I@976|Bacteroidetes,47XC3@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
HKD3_k127_7041690_4	509635.N824_02290	6.233e-63	231.0	COG0457@1|root,COG0457@2|Bacteria,4PNC5@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7051211_9	1461577.CCMH01000009_gene1439	7.749e-46	173.0	COG1087@1|root,COG1087@2|Bacteria,4PM43@976|Bacteroidetes,1IMQ7@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD3_k127_7051211_8	1122605.KB893627_gene2996	4.508e-51	194.0	COG0463@1|root,COG0463@2|Bacteria,4NJKQ@976|Bacteroidetes,1ITWX@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_7051211_3	700598.Niako_3018	1.186e-95	319.0	COG2227@1|root,COG2227@2|Bacteria,4PNUQ@976|Bacteroidetes,1IYVG@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD3_k127_7051211_5	700598.Niako_3019	2.45e-86	292.0	COG0500@1|root,COG0500@2|Bacteria,4NRXV@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD3_k127_7051211_4	700598.Niako_3020	5.508e-87	295.0	COG1216@1|root,COG1216@2|Bacteria,4NKMR@976|Bacteroidetes,1IZ0H@117747|Sphingobacteriia	976|Bacteroidetes	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
HKD3_k127_7051211_7	1267211.KI669560_gene1819	7.708e-65	241.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1IP8T@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_7051211_0	1191523.MROS_1148	6.884e-138	452.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_7051211_1	700598.Niako_7347	7.872e-128	426.0	2BV6Z@1|root,32QKE@2|Bacteria,4PCAH@976|Bacteroidetes,1IZE7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7051211_10	1123248.KB893324_gene1742	2.705e-35	147.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7051211_2	925409.KI911562_gene1473	8.648e-113	368.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HKD3_k127_7051211_6	700598.Niako_7353	7.694e-83	280.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1INYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD3_k127_7051211_11	485918.Cpin_1207	5.692e-35	135.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1IQY4@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
HKD3_k127_7085675_2	700598.Niako_3958	2.596e-30	121.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD3_k127_7085675_0	1123248.KB893316_gene4628	0.0	1150.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes,1IRMG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7085675_1	925409.KI911562_gene2502	5.137e-260	805.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1IP6T@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD3_k127_7088486_2	153721.MYP_4792	1.12e-13	71.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,47MYQ@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
HKD3_k127_7088486_1	925409.KI911562_gene1682	8.122e-117	381.0	COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1IPYJ@117747|Sphingobacteriia	976|Bacteroidetes	F	GMP synthase-glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
HKD3_k127_7088486_0	1267211.KI669560_gene219	1.152e-307	954.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1IRK1@117747|Sphingobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7107344_0	700598.Niako_5673	4.556e-71	245.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HKD3_k127_7107344_1	886379.AEWI01000023_gene67	3.173e-54	208.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4NKK9@976|Bacteroidetes	976|Bacteroidetes	S	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M28
HKD3_k127_7107344_2	886379.AEWI01000023_gene66	1.817e-17	90.0	2E8XD@1|root,3337D@2|Bacteria,4NW3N@976|Bacteroidetes,2FVQT@200643|Bacteroidia,3XKVX@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7112951_1	700598.Niako_6098	7.455e-124	416.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1IQ0V@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
HKD3_k127_7112951_0	925409.KI911562_gene647	5.062e-214	670.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1IQJC@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HKD3_k127_7112951_2	1123248.KB893319_gene4028	1.003e-42	162.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1ISSY@117747|Sphingobacteriia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HKD3_k127_7112951_3	1267211.KI669560_gene1279	1.755e-35	148.0	28TRC@1|root,2ZFYJ@2|Bacteria,4NH2D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7112951_4	1123037.AUDE01000001_gene1776	6.781e-31	126.0	COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,1I39C@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD3_k127_7112951_5	925409.KI911562_gene650	6.606e-11	64.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1IS3Y@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-superfamily hydrolase subfamily IA, variant 3	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD3_k127_7126839_0	945713.IALB_0194	7.564e-95	319.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,YdjC
HKD3_k127_7126839_3	1123278.KB893586_gene527	0.0003251	54.0	COG1874@1|root,COG4625@1|root,COG1874@2|Bacteria,COG4625@2|Bacteria,4PPRU@976|Bacteroidetes,47YR8@768503|Cytophagia	976|Bacteroidetes	GO	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
HKD3_k127_7126839_1	1408473.JHXO01000015_gene1897	2.523e-25	124.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_7126839_2	504472.Slin_4723	1.326e-09	72.0	COG3391@1|root,COG3391@2|Bacteria,4NNI8@976|Bacteroidetes	976|Bacteroidetes	E	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
HKD3_k127_712806_1	1267211.KI669560_gene23	4.071e-98	326.0	COG0491@1|root,COG0491@2|Bacteria,4NHW8@976|Bacteroidetes,1IQ1J@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_712806_0	925409.KI911562_gene362	1.15e-147	478.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1INPB@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HKD3_k127_7132159_0	925409.KI911562_gene1410	5.77e-209	656.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HKD3_k127_7132159_3	1123248.KB893385_gene4786	2.574e-39	149.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1ITA3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD3_k127_7132159_1	925409.KI911562_gene1481	1.02e-166	528.0	COG1208@1|root,COG1208@2|Bacteria,4NIRW@976|Bacteroidetes,1IVAZ@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD3_k127_7132159_4	746697.Aeqsu_1821	1.068e-29	128.0	2E61B@1|root,32DNU@2|Bacteria,4NQ9X@976|Bacteroidetes,1I39V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7132159_2	485918.Cpin_7295	4.37e-141	453.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1IRN3@117747|Sphingobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
HKD3_k127_7164841_3	1550091.JROE01000014_gene4251	3.916e-37	147.0	COG4977@1|root,COG4977@2|Bacteria,4PPWA@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_7164841_0	925409.KI911562_gene680	0.0	1059.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IQ0B@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_7164841_4	675814.VIC_003670	4.519e-36	143.0	COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,1RMVS@1236|Gammaproteobacteria,1XW7B@135623|Vibrionales	135623|Vibrionales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2,SnoaL_2
HKD3_k127_7164841_2	330214.NIDE0008	3.69e-43	162.0	COG2259@1|root,COG2259@2|Bacteria,3J13I@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD3_k127_7164841_1	1239962.C943_03578	4.899e-52	192.0	COG0664@1|root,COG0664@2|Bacteria,4NJRX@976|Bacteroidetes,47QTJ@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_717438_0	700598.Niako_6909	1.147e-226	720.0	COG1629@1|root,COG4771@2|Bacteria,4PKRZ@976|Bacteroidetes,1J0Q2@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_717438_5	1122605.KB893625_gene1858	1.837e-46	171.0	COG2905@1|root,COG2905@2|Bacteria,4NTKX@976|Bacteroidetes,1J0SE@117747|Sphingobacteriia	976|Bacteroidetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_717438_4	1123248.KB893324_gene1749	5.293e-48	178.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1ITDM@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HKD3_k127_717438_3	929713.NIASO_14080	3.615e-59	209.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1ISAN@117747|Sphingobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HKD3_k127_717438_6	929713.NIASO_14075	6.666e-27	112.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1ITY0@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD3_k127_717438_1	1123248.KB893324_gene1752	5.702e-136	443.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HKD3_k127_717438_2	925409.KI911562_gene1196	2.53e-124	404.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_7190420_2	1223410.KN050846_gene2842	1.509e-90	305.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia	976|Bacteroidetes	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
HKD3_k127_7190420_0	1123276.KB893250_gene349	1.938e-186	597.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_7190420_1	1123242.JH636434_gene5275	3.049e-150	490.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
HKD3_k127_7203857_1	555779.Dthio_PD1962	1.138e-12	70.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD3_k127_7203857_0	700598.Niako_7047	5.72e-178	562.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1IQMY@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_7205119_1	485918.Cpin_1903	4.665e-26	109.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1ISBS@117747|Sphingobacteriia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD3_k127_7205119_0	925409.KI911562_gene1864	4.718e-129	418.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD3_k127_7205119_2	1279009.ADICEAN_02824	5.071e-25	114.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_7217306_4	1223410.KN050846_gene2372	0.0002643	43.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes,1I565@117743|Flavobacteriia	976|Bacteroidetes	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
HKD3_k127_7217306_1	700598.Niako_1270	4.877e-175	554.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes,1IRKA@117747|Sphingobacteriia	976|Bacteroidetes	O	SPTR Hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
HKD3_k127_7217306_2	700598.Niako_1271	4.253e-156	501.0	COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes,1IPJ1@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM AIR synthase related protein, N-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
HKD3_k127_7217306_3	986075.CathTA2_0423	4.259e-40	155.0	COG0398@1|root,COG0398@2|Bacteria,1V19V@1239|Firmicutes,4HEIJ@91061|Bacilli	91061|Bacilli	S	PFAM SNARE associated Golgi protein	yqeD	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD3_k127_7217306_0	700598.Niako_5695	2.431e-183	580.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
HKD3_k127_723342_2	468059.AUHA01000005_gene2425	2.186e-76	259.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1IRV7@117747|Sphingobacteriia	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_723342_3	1123057.P872_13055	5.609e-47	171.0	COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,47R9V@768503|Cytophagia	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
HKD3_k127_723342_0	1124780.ANNU01000008_gene2709	2.703e-187	595.0	2CA5R@1|root,2Z81H@2|Bacteria,4NGSF@976|Bacteroidetes,47M6R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
HKD3_k127_723342_4	1121899.Q764_13355	4.302e-05	56.0	COG1345@1|root,COG1345@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Gal_Lectin,Ig_3,PA14
HKD3_k127_723342_1	443143.GM18_0341	1.149e-99	346.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7248493_1	1123248.KB893385_gene4734	1.98e-74	254.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_7248493_0	1123248.KB893385_gene4735	8.55e-102	342.0	COG1835@1|root,COG1835@2|Bacteria,4P0FC@976|Bacteroidetes,1IYEI@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD3_k127_7251835_2	926551.KB900738_gene201	6.926e-64	228.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,1HXJI@117743|Flavobacteriia,1ERFU@1016|Capnocytophaga	976|Bacteroidetes	P	Putative metal-binding domain of cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_7251835_4	1178825.ALIH01000004_gene2891	1.225e-06	51.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia	976|Bacteroidetes	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
HKD3_k127_7251835_0	1123248.KB893386_gene1898	0.0	1167.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
HKD3_k127_7251835_3	485918.Cpin_0682	5.986e-10	61.0	COG2010@1|root,COG2010@2|Bacteria,4PJ6S@976|Bacteroidetes,1IZP1@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7251835_1	700598.Niako_1943	6.268e-84	289.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
HKD3_k127_7252937_4	700598.Niako_4696	8.518e-25	105.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_7252937_1	1173029.JH980292_gene2224	1.847e-59	217.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria,1H8PU@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM UbiA prenyltransferase	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
HKD3_k127_7252937_3	1227739.Hsw_3254	1.706e-25	115.0	298PG@1|root,2ZVTY@2|Bacteria,4NP4F@976|Bacteroidetes,47PR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7252937_0	1267211.KI669560_gene2545	2.614e-268	833.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
HKD3_k127_7252937_2	1123248.KB893324_gene1764	1.28e-38	159.0	28ICP@1|root,314Q6@2|Bacteria,4PIZD@976|Bacteroidetes,1IZ0B@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7270363_2	1279009.ADICEAN_01064	3.631e-46	173.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD3_k127_7270363_1	1267211.KI669560_gene9	4.065e-84	293.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1IRMS@117747|Sphingobacteriia	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
HKD3_k127_7270363_0	555500.I215_15648	2.589e-97	318.0	COG1708@1|root,COG1708@2|Bacteria,4NIND@976|Bacteroidetes,1I02E@117743|Flavobacteriia	976|Bacteroidetes	S	Streptomycin adenylyltransferase	-	-	-	ko:K18236	-	-	-	-	ko00000,ko01504	-	-	-	Adenyl_transf
HKD3_k127_7291542_2	700598.Niako_6694	5.457e-69	241.0	COG0671@1|root,COG0671@2|Bacteria,4NGYP@976|Bacteroidetes,1IR1B@117747|Sphingobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_7291542_1	700598.Niako_6695	1.391e-100	338.0	28K2C@1|root,2Z9RQ@2|Bacteria,4NJP3@976|Bacteroidetes,1ITQ3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7291542_0	1267211.KI669560_gene1027	1.14e-197	625.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_7291542_3	929713.NIASO_13915	9.216e-08	58.0	2EHHG@1|root,33B9E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7298684_0	398525.KB900701_gene7777	1.063e-256	801.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,3JSJ1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
HKD3_k127_7298684_3	1121904.ARBP01000008_gene3232	8.221e-21	93.0	2F3Q3@1|root,33WGW@2|Bacteria,4P300@976|Bacteroidetes,47V6X@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7298684_2	709991.Odosp_2389	1.987e-26	123.0	COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,2FMVP@200643|Bacteroidia,22WVX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Porin subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
HKD3_k127_7298684_1	1107311.Q767_15090	8.11e-58	207.0	COG0560@1|root,COG0560@2|Bacteria,4NIF2@976|Bacteroidetes,1HZ6P@117743|Flavobacteriia,2NT55@237|Flavobacterium	976|Bacteroidetes	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
HKD3_k127_7307139_3	1450525.JATV01000002_gene1906	4.821e-14	72.0	COG0668@1|root,COG0668@2|Bacteria,4NFC6@976|Bacteroidetes,1HZQG@117743|Flavobacteriia,2NTEJ@237|Flavobacterium	976|Bacteroidetes	M	Mechanosensitive ion channel	mscM	-	-	-	-	-	-	-	-	-	-	-	MS_channel
HKD3_k127_7307139_1	1239962.C943_00134	6.166e-83	289.0	28M5B@1|root,2ZAJ4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7307139_0	1121904.ARBP01000018_gene2707	3.427e-176	561.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,47YNU@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
HKD3_k127_7307139_4	1229172.JQFA01000002_gene4821	2.653e-06	55.0	COG2149@1|root,COG2149@2|Bacteria,1G7NV@1117|Cyanobacteria,1HCS7@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
HKD3_k127_7307139_2	1239962.C943_03741	1.728e-37	147.0	2BVY1@1|root,32QYH@2|Bacteria,4NR2M@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7317945_4	468059.AUHA01000005_gene2445	2.778e-13	72.0	COG2149@1|root,COG2149@2|Bacteria,4NW0X@976|Bacteroidetes,1IZG7@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
HKD3_k127_7317945_0	468059.AUHA01000005_gene2446	9.013e-242	753.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IUW3@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_7317945_2	1434325.AZQN01000001_gene665	5.854e-113	371.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_7317945_3	1123248.KB893370_gene5038	1.918e-84	284.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1IV4X@117747|Sphingobacteriia	976|Bacteroidetes	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_7317945_1	860228.Ccan_14180	1.028e-127	422.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia,1ESQ1@1016|Capnocytophaga	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_7317945_5	1121897.AUGO01000015_gene3335	2.719e-12	67.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1HZXZ@117743|Flavobacteriia,2NT8V@237|Flavobacterium	976|Bacteroidetes	S	Iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
HKD3_k127_7326596_3	925409.KI911562_gene202	3.313e-85	286.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
HKD3_k127_7326596_5	1123248.KB893314_gene3391	2.336e-43	160.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1ITKQ@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HKD3_k127_7326596_4	700598.Niako_7071	4.946e-59	209.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1ISVB@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HKD3_k127_7326596_2	1123248.KB893314_gene3393	4.532e-94	311.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1IS7C@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
HKD3_k127_7326596_0	1123248.KB893314_gene3394	3.758e-161	514.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1IR49@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HKD3_k127_7326596_1	1122605.KB893644_gene1411	1.083e-148	473.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
HKD3_k127_7333483_0	929713.NIASO_17660	5.413e-241	758.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1IQ58@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_7333483_2	700598.Niako_5711	9.193e-40	151.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1ISV5@117747|Sphingobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD3_k127_7333483_1	1123248.KB893385_gene4877	1.173e-40	155.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1IPJE@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
HKD3_k127_7344858_5	1313301.AUGC01000011_gene1144	1.788e-38	148.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD3_k127_7344858_3	925409.KI911562_gene3006	2.037e-102	342.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
HKD3_k127_7344858_7	925409.KI911562_gene3005	9.969e-12	71.0	2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
HKD3_k127_7344858_1	714943.Mucpa_1920	4.26e-128	412.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD3_k127_7344858_2	468059.AUHA01000005_gene2577	8.477e-111	361.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD3_k127_7344858_4	1267211.KI669560_gene1215	4.928e-89	301.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_7344858_0	1267211.KI669560_gene1216	1.181e-213	671.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
HKD3_k127_7344858_6	1267211.KI669560_gene1277	8.711e-32	126.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1IRGQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_7344858_8	485918.Cpin_2151	2.161e-05	46.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1IRGQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_7354193_1	1123035.ARLA01000021_gene877	1.137e-11	65.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia,4C31M@83612|Psychroflexus	976|Bacteroidetes	M	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD3_k127_7354193_0	700598.Niako_0407	1.163e-145	470.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1IPTV@117747|Sphingobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD3_k127_7355855_0	760192.Halhy_4845	2.388e-186	591.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1IQ3V@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
HKD3_k127_7355855_1	1166018.FAES_3022	1.112e-08	60.0	COG4980@1|root,COG4980@2|Bacteria,4NR7R@976|Bacteroidetes,47QX5@768503|Cytophagia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
HKD3_k127_7366546_2	929713.NIASO_05760	1.785e-99	336.0	COG1807@1|root,COG1807@2|Bacteria,4NHXW@976|Bacteroidetes,1IR5R@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_7366546_0	509635.N824_08485	0.0	1204.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQMB@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD3_k127_7366546_1	1185876.BN8_02716	5.785e-138	445.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,47N64@768503|Cytophagia	976|Bacteroidetes	C	COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
HKD3_k127_7366546_3	1122605.KB893626_gene2661	1.007e-74	254.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1IPV4@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HKD3_k127_7445556_2	1123248.KB893316_gene4559	4.897e-83	279.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7445556_0	1123248.KB893337_gene2460	0.0	1065.0	COG4206@1|root,COG4206@2|Bacteria,4PKY5@976|Bacteroidetes,1IQUU@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
HKD3_k127_7445556_1	760192.Halhy_1263	6.257e-195	623.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_7445556_3	468059.AUHA01000002_gene918	1.338e-52	193.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1IY5W@117747|Sphingobacteriia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
HKD3_k127_7447877_7	1267211.KI669560_gene1965	7.629e-25	106.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1IU0V@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HKD3_k127_7447877_4	925409.KI911562_gene2091	1.78e-57	201.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1ISA4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD3_k127_7447877_0	925409.KI911562_gene2092	1.266e-284	877.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1IQUN@117747|Sphingobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD3_k127_7447877_5	485918.Cpin_3583	2.273e-39	151.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,1IUA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
HKD3_k127_7447877_6	925409.KI911562_gene2280	2.727e-27	116.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD3_k127_7447877_2	485918.Cpin_6220	4.383e-65	225.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1ISFT@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HKD3_k127_7447877_3	925409.KI911562_gene2282	1.312e-59	211.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
HKD3_k127_745034_1	929703.KE386491_gene219	2.377e-57	204.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_745034_2	926549.KI421517_gene2403	8.313e-42	160.0	29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,47RB5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_745034_0	471854.Dfer_4568	3.766e-191	618.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,47XXA@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7490961_0	925409.KI911562_gene2942	1.036e-285	891.0	COG0448@1|root,COG0448@2|Bacteria,4PKFG@976|Bacteroidetes,1IPMM@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
HKD3_k127_7490961_2	1267211.KI669560_gene2326	1.435e-153	490.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1IX1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_7490961_3	700598.Niako_4732	4.894e-128	424.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1IS31@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
HKD3_k127_7490961_1	700598.Niako_2561	1.346e-169	540.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1IQ9P@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_7499428_3	760192.Halhy_2436	2.91e-34	141.0	COG2010@1|root,COG2010@2|Bacteria,4NX4D@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7499428_4	700598.Niako_0924	6.112e-29	120.0	2E3Q9@1|root,32YN7@2|Bacteria,4NWH3@976|Bacteroidetes,1IZ69@117747|Sphingobacteriia	976|Bacteroidetes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
HKD3_k127_7499428_2	700598.Niako_6017	1.259e-96	319.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1INZ4@117747|Sphingobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HKD3_k127_7499428_1	700598.Niako_6417	4.073e-141	455.0	COG1052@1|root,COG1052@2|Bacteria,4NF1R@976|Bacteroidetes,1IRC8@117747|Sphingobacteriia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_7499428_0	925409.KI911562_gene442	1.301e-178	568.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_7499428_5	468059.AUHA01000007_gene2695	9.115e-14	76.0	2CEQ4@1|root,2ZUK4@2|Bacteria,4NPFT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7520860_0	760192.Halhy_2333	2.65e-126	416.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1IPF0@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08156	-	-	-	-	ko00000,ko02000	2.A.1.2.14	-	-	MFS_1,Sugar_tr
HKD3_k127_7520860_1	1267211.KI669560_gene2391	1.594e-43	165.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_7526313_1	1123248.KB893320_gene3890	9.348e-38	151.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_7526313_0	925409.KI911562_gene2832	2.939e-120	389.0	COG0443@1|root,COG0443@2|Bacteria,4NEHZ@976|Bacteroidetes,1IQ1C@117747|Sphingobacteriia	976|Bacteroidetes	O	heat shock protein 70	-	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
HKD3_k127_7527232_6	1122605.KB893643_gene604	1.935e-86	301.0	28M10@1|root,2ZAFW@2|Bacteria,4NIF8@976|Bacteroidetes,1ISGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
HKD3_k127_7527232_9	1267211.KI669560_gene2691	1.696e-60	220.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes	976|Bacteroidetes	S	Hydrolase with alpha beta fold protein	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD3_k127_7527232_3	1267211.KI669560_gene2690	6.004e-137	439.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1IVZZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD3_k127_7527232_13	984262.SGRA_3491	1.344e-18	89.0	COG0607@1|root,COG0607@2|Bacteria,4P7K2@976|Bacteroidetes,1J038@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD3_k127_7527232_0	700598.Niako_7346	0.0	1010.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1IP14@117747|Sphingobacteriia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
HKD3_k127_7527232_12	1515615.HQ41_05215	4.138e-26	111.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,2FUP5@200643|Bacteroidia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD3_k127_7527232_5	1123248.KB893326_gene1492	1.674e-86	294.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1IQEI@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
HKD3_k127_7527232_11	391598.FBBAL38_09074	7.578e-33	132.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes,1I2UM@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_7527232_8	925409.KI911562_gene2583	8.428e-68	240.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1IRW3@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NlpC P60 family	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
HKD3_k127_7527232_10	700598.Niako_3952	4.742e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_7527232_2	1123248.KB893337_gene2579	8.756e-170	535.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_7527232_4	925409.KI911562_gene2348	1.02e-136	442.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD3_k127_7527232_1	485918.Cpin_5494	1.005e-263	821.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1IPXI@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD3_k127_7527232_7	925409.KI911562_gene1819	1.137e-75	256.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1ITJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD3_k127_753089_0	925409.KI911562_gene2578	1.634e-248	771.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1IQY7@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_7537085_4	1379270.AUXF01000001_gene2292	2.914e-16	89.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
HKD3_k127_7537085_2	929562.Emtol_1980	2.532e-52	189.0	COG0457@1|root,COG0457@2|Bacteria,4PN8J@976|Bacteroidetes,47YES@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_7537085_3	1089547.KB913013_gene2813	9.343e-24	105.0	COG4538@1|root,COG4538@2|Bacteria,4NX66@976|Bacteroidetes,47XBQ@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD3_k127_7537085_1	714943.Mucpa_4224	2.056e-56	206.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_7537085_0	925409.KI911562_gene2249	3.16e-245	759.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,1INSE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_7537085_5	1122179.KB890430_gene4318	7.547e-05	49.0	COG3577@1|root,COG3577@2|Bacteria,4PMR9@976|Bacteroidetes	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
HKD3_k127_7542505_1	1282361.ABAC402_01220	4.837e-60	217.0	COG3867@1|root,COG3867@2|Bacteria,1R33X@1224|Proteobacteria,2U17E@28211|Alphaproteobacteria,2KHND@204458|Caulobacterales	204458|Caulobacterales	G	PFAM glycosyl hydrolase 53 domain protein	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
HKD3_k127_7542505_2	1131812.JQMS01000001_gene1464	7.114e-47	172.0	COG0346@1|root,COG0346@2|Bacteria,4NQRN@976|Bacteroidetes,1I2S1@117743|Flavobacteriia,2NWXQ@237|Flavobacterium	976|Bacteroidetes	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
HKD3_k127_7542505_0	925409.KI911562_gene517	1.386e-103	342.0	COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,1IT39@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_7542505_3	700598.Niako_1024	2.825e-23	104.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD3_k127_754583_0	1267211.KI669560_gene1455	3.177e-233	725.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1IQIR@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HKD3_k127_754583_2	1123248.KB893314_gene3555	6.763e-89	305.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_754583_5	925409.KI911562_gene2206	1.54e-60	216.0	COG0241@1|root,COG0241@2|Bacteria,4NR54@976|Bacteroidetes,1IU3D@117747|Sphingobacteriia	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,PNK3P
HKD3_k127_754583_6	1122605.KB893637_gene3156	7.894e-47	177.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,1IPMP@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
HKD3_k127_754583_4	929713.NIASO_09035	1.454e-75	258.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IRJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
HKD3_k127_754583_1	1123248.KB893317_gene4285	1.274e-133	434.0	COG2605@1|root,COG2605@2|Bacteria,4NHEN@976|Bacteroidetes,1IU21@117747|Sphingobacteriia	976|Bacteroidetes	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_754583_3	925409.KI911562_gene2208	1.182e-86	293.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_7546795_0	1267211.KI669560_gene518	2.328e-247	771.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_7546795_1	1267211.KI669560_gene519	3.029e-190	602.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1IR43@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_7546795_3	925409.KI911562_gene2497	3.328e-48	178.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1IU44@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7546795_4	1107311.Q767_03910	7.915e-24	111.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,1I22Y@117743|Flavobacteriia,2NVTZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_7546795_2	1267211.KI669560_gene348	1.594e-79	267.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVNR@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_7557742_3	929556.Solca_2696	1.569e-29	120.0	COG2755@1|root,COG2755@2|Bacteria,4NPB3@976|Bacteroidetes,1J195@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_7557742_1	929556.Solca_2698	7.671e-165	523.0	2DB9J@1|root,2Z7X1@2|Bacteria,4NGUY@976|Bacteroidetes,1IQJ4@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109
HKD3_k127_7557742_0	700598.Niako_5240	1.263e-190	601.0	COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes,1IR54@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	ce	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
HKD3_k127_7557742_2	929556.Solca_2701	2.056e-106	353.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HKD3_k127_7563663_0	1121899.Q764_07535	6.678e-71	246.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia,2NUFJ@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7563663_2	1121896.JMLU01000024_gene2526	7.242e-35	139.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia,2NUFJ@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7563663_1	1121889.AUDM01000004_gene2658	5.306e-66	230.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia,2NV62@237|Flavobacterium	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HKD3_k127_7563663_3	1267211.KI669560_gene1631	4.715e-16	78.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes,1J0FW@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD3_k127_7580211_2	91464.S7335_442	2.075e-42	158.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1GYN6@1129|Synechococcus	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HKD3_k127_7580211_0	338966.Ppro_0419	6.983e-296	921.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,43U1C@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD3_k127_7580211_1	700598.Niako_6198	2.095e-102	335.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
HKD3_k127_7585473_2	1123248.KB893315_gene3160	6.253e-41	152.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_7585473_4	1123248.KB893319_gene3959	1.134e-21	99.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1IPBV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
HKD3_k127_7585473_3	925409.KI911562_gene2895	4.862e-33	131.0	COG1393@1|root,COG1393@2|Bacteria,4NSJ5@976|Bacteroidetes,1ITCN@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
HKD3_k127_7585473_1	1453500.AT05_07905	5.954e-49	177.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,1I3D1@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD3_k127_7585473_6	926549.KI421517_gene4076	1.342e-09	68.0	28JU1@1|root,2Z9J4@2|Bacteria,4NV4K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
HKD3_k127_7585473_0	1267211.KI669560_gene2755	1.781e-65	226.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD3_k127_7606375_1	1239962.C943_00134	1.487e-08	59.0	28M5B@1|root,2ZAJ4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7606375_0	1239962.C943_00983	5.287e-144	466.0	COG0025@1|root,COG0025@2|Bacteria,4NM79@976|Bacteroidetes,47U8Y@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD3_k127_7621202_0	925409.KI911562_gene2367	0.0	1514.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD3_k127_7627531_1	1166018.FAES_2159	3.439e-151	486.0	COG3538@1|root,COG3538@2|Bacteria,4NGY6@976|Bacteroidetes,47JIR@768503|Cytophagia	976|Bacteroidetes	S	Pfam:DUF1237	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
HKD3_k127_7627531_2	1123248.KB893331_gene3789	2.08e-138	445.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1IREV@117747|Sphingobacteriia	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
HKD3_k127_7627531_0	1123248.KB893331_gene3788	0.0	1304.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1IQ2I@117747|Sphingobacteriia	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
HKD3_k127_7627531_3	1089547.KB913013_gene4107	6.506e-59	216.0	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,47P9G@768503|Cytophagia	976|Bacteroidetes	M	PFAM Fasciclin domain	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	Fasciclin
HKD3_k127_7635852_0	1121481.AUAS01000001_gene4900	8.129e-119	390.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
HKD3_k127_7635852_1	485917.Phep_2200	4.26e-88	302.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IRG0@117747|Sphingobacteriia	976|Bacteroidetes	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD3_k127_7635852_2	1123248.KB893324_gene1747	2.032e-71	246.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IPHC@117747|Sphingobacteriia	976|Bacteroidetes	V	peptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD3_k127_7635852_3	929562.Emtol_0744	6.13e-20	89.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,47KS4@768503|Cytophagia	976|Bacteroidetes	V	peptidase U61 LD-carboxypeptidase A	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD3_k127_7641306_0	925409.KI911562_gene2687	0.0	1479.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1IPD0@117747|Sphingobacteriia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD3_k127_7641306_1	485918.Cpin_2320	0.0	1019.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1IQQU@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7659332_0	761193.Runsl_0169	1.443e-231	737.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47K4Y@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
HKD3_k127_7669717_0	700598.Niako_6637	1.191e-124	410.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_7669717_1	700598.Niako_6624	5.02e-50	196.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1IR9Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
HKD3_k127_7677492_4	926562.Oweho_1260	7.519e-13	73.0	2AEUM@1|root,314S0@2|Bacteria,4PJ0U@976|Bacteroidetes,1ICTR@117743|Flavobacteriia,2PC4S@246874|Cryomorphaceae	976|Bacteroidetes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
HKD3_k127_7677492_5	344747.PM8797T_14901	5.754e-05	55.0	COG2010@1|root,COG2010@2|Bacteria,2IY6K@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
HKD3_k127_7677492_3	700598.Niako_3291	7.449e-28	120.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,1IY6E@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Lipid polyisoprenoid-binding, YceI-like	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_7677492_2	926562.Oweho_1264	6.83e-46	178.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,2PAYC@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7677492_0	504472.Slin_1563	0.0	1319.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6,Sortilin-Vps10
HKD3_k127_7677492_1	391596.PBAL39_08706	2.294e-58	206.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1IUVA@117747|Sphingobacteriia	976|Bacteroidetes	O	Flavin-binding monooxygenase-like	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
HKD3_k127_7687454_0	509635.N824_12040	2.457e-121	413.0	COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,1IQEM@117747|Sphingobacteriia	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_V_gamma,PDDEXK_1
HKD3_k127_7687454_1	742767.HMPREF9456_01870	1.33e-67	252.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,2FMHG@200643|Bacteroidia,22W5V@171551|Porphyromonadaceae	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
HKD3_k127_7688407_0	925409.KI911562_gene1450	4.786e-124	402.0	COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,1IPTD@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD3_k127_7688407_1	1122605.KB893628_gene4451	1.152e-53	201.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1IPAT@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
HKD3_k127_7706526_5	700598.Niako_6783	3.369e-110	359.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,1IQAV@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_7706526_2	391596.PBAL39_11972	4.986e-146	468.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1IQ44@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
HKD3_k127_7706526_1	1449345.JHWC01000002_gene1401	2.056e-165	527.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_7706526_6	1123248.KB893348_gene85	1.566e-95	326.0	COG0438@1|root,COG0438@2|Bacteria,4NF7J@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_7706526_4	1267211.KI669560_gene804	6.951e-137	440.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,1IS5U@117747|Sphingobacteriia	976|Bacteroidetes	K	MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
HKD3_k127_7706526_7	700598.Niako_6787	2.542e-81	273.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,1IPYA@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_7706526_0	1267211.KI669560_gene806	1.231e-220	693.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1IQI6@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1233 Phytoene dehydrogenase and related	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_7706526_3	1267211.KI669560_gene807	2.847e-138	444.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1IP80@117747|Sphingobacteriia	976|Bacteroidetes	I	Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
HKD3_k127_7706526_8	700598.Niako_6788	1.101e-65	228.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1ISDP@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
HKD3_k127_7724532_7	1123248.KB893314_gene3476	1.576e-70	246.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
HKD3_k127_7724532_3	1267211.KI669560_gene1462	4.529e-111	362.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD3_k127_7724532_1	929713.NIASO_04810	4.363e-177	563.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_7724532_4	700598.Niako_0903	8.182e-110	365.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1IQGU@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HKD3_k127_7724532_2	925409.KI911562_gene2691	1.492e-135	439.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD3_k127_7724532_6	1123248.KB893316_gene4629	5.539e-89	304.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7724532_5	1454007.JAUG01000127_gene351	1.339e-96	326.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IPM0@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
HKD3_k127_7724532_11	1122605.KB893629_gene4103	1.292e-07	63.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiA
HKD3_k127_7724532_0	1123248.KB893359_gene2106	6.762e-197	618.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD3_k127_7724532_9	1313421.JHBV01000008_gene4393	2.581e-22	107.0	2ERGI@1|root,33J21@2|Bacteria,4NY8V@976|Bacteroidetes,1IZPK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7724532_8	1267211.KI669560_gene747	2.133e-54	193.0	2DBS0@1|root,2ZANT@2|Bacteria,4NQP3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7739683_2	504472.Slin_3979	7.748e-75	265.0	COG4198@1|root,COG4198@2|Bacteria,4NI11@976|Bacteroidetes,47NFX@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like
HKD3_k127_7739683_0	1492737.FEM08_11620	1.387e-215	706.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia,2P0KH@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7739683_1	1550091.JROE01000008_gene3583	2.675e-108	364.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IQ0I@117747|Sphingobacteriia	976|Bacteroidetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
HKD3_k127_7739683_3	700598.Niako_4454	2.816e-53	191.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1IPSN@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HKD3_k127_7743427_2	700598.Niako_2199	3.04e-78	265.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1IR41@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
HKD3_k127_7743427_1	313596.RB2501_04010	6.54e-120	404.0	COG2114@1|root,COG2114@2|Bacteria,4PMA6@976|Bacteroidetes,1IJPA@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,Guanylate_cyc
HKD3_k127_7743427_3	118173.KB235914_gene2451	1.12e-55	196.0	COG0745@1|root,COG0745@2|Bacteria,1G5XG@1117|Cyanobacteria,1HB6Y@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HKD3_k127_7743427_0	1267534.KB906756_gene667	5.397e-218	689.0	COG0642@1|root,COG2199@1|root,COG2203@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PilZ,Response_reg,Y_Y_Y
HKD3_k127_7778818_1	1123008.KB905695_gene2721	6.346e-57	203.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,2FNX2@200643|Bacteroidia,22X31@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
HKD3_k127_7778818_0	700598.Niako_6564	4.553e-127	416.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IRWK@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD3_k127_7778818_2	883096.HMPREF9699_00133	4.294e-08	59.0	2DQVY@1|root,338ZT@2|Bacteria,4NVHS@976|Bacteroidetes,1I6PR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7784607_0	40373.F991_00619	1.44e-08	68.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,3NIKG@468|Moraxellaceae	1236|Gammaproteobacteria	O	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_7805825_1	756272.Plabr_3731	1.394e-14	87.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7805825_0	700598.Niako_2108	5.837e-132	431.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HKD3_k127_782750_1	925409.KI911562_gene2120	7.239e-142	455.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1INMG@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
HKD3_k127_782750_2	700598.Niako_2699	2.069e-85	296.0	COG0639@1|root,COG1225@1|root,COG0639@2|Bacteria,COG1225@2|Bacteria,4NME8@976|Bacteroidetes,1IUY5@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_782750_0	1341181.FLJC2902T_24040	1.13e-203	649.0	COG2985@1|root,COG2985@2|Bacteria,4NHM3@976|Bacteroidetes,1IIQ6@117743|Flavobacteriia,2NUWV@237|Flavobacterium	976|Bacteroidetes	U	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
HKD3_k127_782750_3	388413.ALPR1_02215	8.84e-47	179.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47N98@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
HKD3_k127_7833051_5	760192.Halhy_3044	6.084e-11	70.0	COG1266@1|root,COG1266@2|Bacteria,4P5RH@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD3_k127_7833051_1	1185876.BN8_04280	4.272e-83	287.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,47KEU@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
HKD3_k127_7833051_0	1122605.KB893628_gene4474	1.603e-91	305.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,1ITBG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_7833051_4	1408813.AYMG01000014_gene1696	5.954e-12	74.0	2EMGK@1|root,33F59@2|Bacteria,4NYBS@976|Bacteroidetes,1IUEQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7833051_2	1313301.AUGC01000003_gene2119	1.293e-36	148.0	COG1266@1|root,COG1266@2|Bacteria,4P5RH@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD3_k127_7833051_3	1267211.KI669560_gene347	1.886e-28	124.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,Cadherin-like,Calx-beta,Flg_new
HKD3_k127_7837282_0	1123248.KB893348_gene334	3.673e-205	646.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_7837282_1	1237149.C900_04940	3.92e-65	228.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_7849629_3	925409.KI911562_gene806	5.172e-71	241.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1INWY@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HKD3_k127_7849629_2	700598.Niako_6975	4.869e-102	336.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1IQ9Q@117747|Sphingobacteriia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HKD3_k127_7849629_0	1122605.KB893645_gene1094	5.918e-226	706.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1IPSV@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_7849629_1	929713.NIASO_07860	4.856e-128	419.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD3_k127_7875306_1	700598.Niako_0106	3.817e-218	678.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1IQ69@117747|Sphingobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
HKD3_k127_7875306_2	700598.Niako_0107	2.511e-202	637.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1INNU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
HKD3_k127_7875306_0	925409.KI911562_gene1982	9.82e-321	987.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1IP8F@117747|Sphingobacteriia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD3_k127_7876867_0	1121957.ATVL01000009_gene1228	3.171e-166	540.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,4NHSQ@976|Bacteroidetes,47KNM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_7876867_4	925409.KI911562_gene477	3.85e-30	121.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1IU5M@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
HKD3_k127_7876867_3	925409.KI911562_gene478	4.784e-41	152.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1IYVW@117747|Sphingobacteriia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_7876867_2	700598.Niako_6029	1.613e-123	400.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD3_k127_7876867_1	1123248.KB893315_gene2990	1.984e-161	515.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1IP2N@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein required for spore maturation in B.subtilis	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HKD3_k127_7892608_2	1123248.KB893328_gene900	4.414e-64	226.0	COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,1IS9J@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_7892608_0	700598.Niako_5097	8.389e-138	443.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,1IQR5@117747|Sphingobacteriia	976|Bacteroidetes	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
HKD3_k127_7892608_1	925409.KI911562_gene368	8.253e-72	247.0	COG0122@1|root,COG0122@2|Bacteria,4NMMI@976|Bacteroidetes,1IU7D@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM HhH-GPD superfamily base excision DNA repair protein	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HKD3_k127_7892608_3	926559.JoomaDRAFT_0195	4.406e-29	120.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
HKD3_k127_7902375_6	1267211.KI669560_gene372	6.608e-38	144.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_7902375_4	925409.KI911562_gene867	3.303e-83	286.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD3_k127_7902375_3	1267211.KI669560_gene670	1.074e-111	364.0	COG4947@1|root,COG4947@2|Bacteria,4NJWM@976|Bacteroidetes,1IVCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_7902375_5	925409.KI911562_gene610	3.181e-80	273.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1IRC3@117747|Sphingobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HKD3_k127_7902375_1	1239962.C943_04547	2.166e-133	434.0	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,47NA8@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_7902375_7	1122621.ATZA01000002_gene1567	1.082e-37	148.0	COG5654@1|root,COG5654@2|Bacteria,4NTUP@976|Bacteroidetes,1IZ2I@117747|Sphingobacteriia	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
HKD3_k127_7902375_8	1122621.ATZA01000002_gene1568	4.809e-29	122.0	COG5642@1|root,COG5642@2|Bacteria,4NT6I@976|Bacteroidetes,1IZ43@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
HKD3_k127_7902375_2	1123248.KB893322_gene588	2.742e-122	397.0	COG1028@1|root,COG1028@2|Bacteria,4NIAZ@976|Bacteroidetes,1IUVU@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
HKD3_k127_7902375_0	694427.Palpr_0627	8.683e-190	616.0	COG0507@1|root,COG0514@1|root,COG0507@2|Bacteria,COG0514@2|Bacteria,4NF6J@976|Bacteroidetes,2FM19@200643|Bacteroidia,22X68@171551|Porphyromonadaceae	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	uvrD2	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
HKD3_k127_7915527_1	1123248.KB893359_gene2056	2.067e-65	227.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1ISFT@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HKD3_k127_7915527_0	925409.KI911562_gene2282	8.747e-96	322.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
HKD3_k127_7925949_4	1122176.KB903544_gene722	2.528e-32	140.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_7925949_0	661478.OP10G_0632	2.3e-130	422.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
HKD3_k127_7925949_3	1223410.KN050846_gene1984	4.332e-34	135.0	COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes,1I4GX@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
HKD3_k127_7925949_2	1233950.IW22_22210	4.114e-45	167.0	arCOG06733@1|root,313GU@2|Bacteria,4NQIM@976|Bacteroidetes,1I3KE@117743|Flavobacteriia,3ZTM4@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7925949_1	1233950.IW22_22215	3.058e-74	258.0	arCOG07533@1|root,2ZF5I@2|Bacteria,4NMWZ@976|Bacteroidetes,1I1RR@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
HKD3_k127_7931518_0	485918.Cpin_1305	4.885e-315	975.0	COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD3_k127_7931518_1	1123248.KB893381_gene1114	4.765e-08	57.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,1IQ0H@117747|Sphingobacteriia	976|Bacteroidetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HKD3_k127_7932125_1	700598.Niako_6338	1.64e-189	597.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1INTV@117747|Sphingobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD3_k127_7932125_3	1121904.ARBP01000001_gene5557	7.966e-59	209.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,47QAB@768503|Cytophagia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD3_k127_7932125_0	925409.KI911562_gene2835	1.86e-279	865.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1IR48@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD3_k127_7932125_2	1202532.FF52_10988	9.2e-132	467.0	COG1345@1|root,COG4932@1|root,COG1345@2|Bacteria,COG4932@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3
HKD3_k127_794115_2	1227739.Hsw_3202	1.551e-86	293.0	COG5549@1|root,COG5549@2|Bacteria,4NGSZ@976|Bacteroidetes,47SS0@768503|Cytophagia	976|Bacteroidetes	O	Dual-action HEIGH metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M57
HKD3_k127_794115_1	929713.NIASO_00115	1.747e-107	355.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD3_k127_794115_3	925409.KI911562_gene1545	1.892e-81	281.0	COG0412@1|root,COG0412@2|Bacteria,4NE8V@976|Bacteroidetes,1IS6I@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
HKD3_k127_794115_0	700598.Niako_4709	9.434e-238	739.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1IP4J@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HKD3_k127_7974113_2	929562.Emtol_2032	9.611e-50	186.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_7974113_1	1218108.KB908295_gene1966	6.219e-75	261.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1HZ3G@117743|Flavobacteriia	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
HKD3_k127_7974113_0	925409.KI911562_gene748	2.457e-190	601.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1IPI0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_7974113_3	1123248.KB893348_gene278	9.62e-47	175.0	COG0860@1|root,COG0860@2|Bacteria,4NH6Q@976|Bacteroidetes	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
HKD3_k127_7975957_0	471854.Dfer_4322	1.396e-272	884.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
HKD3_k127_7975957_1	1123248.KB893315_gene3012	4.178e-126	410.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HKD3_k127_7988460_0	700598.Niako_1523	1.348e-56	204.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_7988460_2	925409.KI911562_gene2668	3.295e-46	169.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,1IT2H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HKD3_k127_7988460_1	1123248.KB893315_gene3119	5.209e-55	199.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1IQ34@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HKD3_k127_7992828_1	391596.PBAL39_02397	1.272e-117	384.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IV50@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD3_k127_7992828_0	1048983.EL17_08230	7.173e-259	813.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,47N3E@768503|Cytophagia	976|Bacteroidetes	G	Beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_8002309_2	485918.Cpin_2010	4.98e-91	310.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1IUSP@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_8002309_1	1121875.KB907547_gene3049	9.881e-127	412.0	COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,1I05E@117743|Flavobacteriia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD3_k127_8002309_3	485918.Cpin_2008	2.483e-21	94.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1IV9H@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_8002309_0	1358423.N180_03265	9.225e-128	417.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1IV9H@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_8014347_0	1123248.KB893370_gene4996	5.039e-52	187.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,1ITI2@117747|Sphingobacteriia	976|Bacteroidetes	S	Gnat family	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
HKD3_k127_8014347_2	468059.AUHA01000006_gene2992	1.255e-26	112.0	COG3408@1|root,COG3408@2|Bacteria,4NFHH@976|Bacteroidetes,1IREP@117747|Sphingobacteriia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
HKD3_k127_8031237_1	925409.KI911562_gene2937	1.17e-288	895.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_8031237_6	929556.Solca_1404	7.121e-34	137.0	COG0824@1|root,COG0824@2|Bacteria,4NR2W@976|Bacteroidetes,1ITIH@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
HKD3_k127_8031237_0	1267211.KI669560_gene1907	8.25e-303	934.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1IPKK@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG0058 Glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
HKD3_k127_8031237_5	1237149.C900_03495	2.182e-44	164.0	COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,47QK8@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
HKD3_k127_8031237_2	1123248.KB893321_gene504	1.009e-71	254.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1IS2N@117747|Sphingobacteriia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD3_k127_8031237_3	866536.Belba_0068	1.835e-68	236.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,47NUB@768503|Cytophagia	976|Bacteroidetes	P	PFAM ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HKD3_k127_804557_1	700598.Niako_7077	4.895e-117	387.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD3_k127_804557_0	700598.Niako_7078	1.931e-124	404.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HKD3_k127_804557_4	925409.KI911562_gene1313	6.093e-57	205.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,1IRXT@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD3_k127_804557_3	1267211.KI669560_gene970	2.554e-71	245.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD3_k127_804557_2	925409.KI911562_gene1315	1.039e-103	343.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HKD3_k127_8053560_0	700598.Niako_6283	1.129e-93	316.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1IXIZ@117747|Sphingobacteriia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
HKD3_k127_8053560_1	1267211.KI669560_gene135	2.435e-89	300.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_16,TPR_8
HKD3_k127_8088530_0	1220589.CD32_10555	3.027e-83	284.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,3IZ1A@400634|Lysinibacillus	91061|Bacilli	P	Natural resistance-associated macrophage protein	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_8088530_1	925409.KI911562_gene1783	2.857e-58	212.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,1ISAD@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
HKD3_k127_8088530_2	925409.KI911562_gene1782	3.234e-16	83.0	2EC7G@1|root,33661@2|Bacteria,4NWXP@976|Bacteroidetes,1IU01@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4288
HKD3_k127_8089040_3	700598.Niako_6674	1.231e-42	164.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1IRWM@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
HKD3_k127_8089040_4	700598.Niako_6673	5.499e-20	98.0	COG1250@1|root,COG1250@2|Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.108,1.1.1.157	ko:K00074,ko:K17735	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N,4HBT_2
HKD3_k127_8089040_2	1267211.KI669560_gene63	4.759e-51	185.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1ISZW@117747|Sphingobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HKD3_k127_8089040_0	925409.KI911562_gene408	0.0	1746.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD3_k127_8089040_1	485918.Cpin_4197	4.355e-51	203.0	COG4733@1|root,COG4733@2|Bacteria,4PKY7@976|Bacteroidetes,1J0NC@117747|Sphingobacteriia	976|Bacteroidetes	O	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PPC,Reprolysin_4,fn3
HKD3_k127_8089040_5	1239962.C943_01324	6.875e-06	59.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
HKD3_k127_8105043_3	866536.Belba_0405	1.858e-09	61.0	COG4319@1|root,COG4319@2|Bacteria,4NMRK@976|Bacteroidetes,47PBC@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_8105043_2	925409.KI911562_gene2497	7.599e-31	128.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1IU44@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8105043_1	700598.Niako_6249	3.635e-126	410.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1IQR6@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD3_k127_8105043_0	485918.Cpin_0849	8.34e-150	484.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
HKD3_k127_8127203_1	1123248.KB893355_gene4712	3.232e-56	199.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
HKD3_k127_8127203_0	1267211.KI669560_gene2835	5.527e-271	841.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes	976|Bacteroidetes	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_8127203_2	1270196.JCKI01000003_gene2266	1.707e-15	79.0	COG2374@1|root,COG3210@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG2374@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,4NTNN@976|Bacteroidetes,1J0H7@117747|Sphingobacteriia	976|Bacteroidetes	MU	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
HKD3_k127_8136593_3	1122605.KB893644_gene1329	7.95e-14	81.0	28IVH@1|root,2Z8TX@2|Bacteria,4NEEW@976|Bacteroidetes,1IQEF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
HKD3_k127_8136593_2	1270196.JCKI01000001_gene4154	1.87e-14	83.0	29GF6@1|root,303CZ@2|Bacteria,4NR6I@976|Bacteroidetes,1IT48@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
HKD3_k127_8136593_0	391596.PBAL39_09936	1.481e-104	349.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1IQH7@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Integral membrane protein DUF95	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
HKD3_k127_8136593_1	700598.Niako_2002	3.035e-51	191.0	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1IRZA@117747|Sphingobacteriia	976|Bacteroidetes	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD3_k127_8198717_3	1202532.FF52_02225	1.984e-52	193.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia,2NSK8@237|Flavobacterium	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_8198717_0	1121957.ATVL01000010_gene597	4.14e-131	431.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,47NNC@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_8198717_2	1121904.ARBP01000006_gene3777	1.275e-69	239.0	COG4430@1|root,COG4430@2|Bacteria,4NQJJ@976|Bacteroidetes,47QKU@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
HKD3_k127_8198717_1	485918.Cpin_0408	5.413e-74	262.0	COG3291@1|root,COG3291@2|Bacteria,4NQ3X@976|Bacteroidetes,1IXCU@117747|Sphingobacteriia	976|Bacteroidetes	M	Legume lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Lectin_legB,PKD
HKD3_k127_8200043_4	700598.Niako_5540	6.472e-57	199.0	COG1978@1|root,COG1978@2|Bacteria,4NNSE@976|Bacteroidetes,1IS2T@117747|Sphingobacteriia	976|Bacteroidetes	S	Ribonuclease H-like	-	-	-	ko:K09776	-	-	-	-	ko00000	-	-	-	RNaseH_like
HKD3_k127_8200043_2	929713.NIASO_00270	3.222e-82	278.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1ISQ4@117747|Sphingobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD3_k127_8200043_3	1341181.FLJC2902T_00320	2.535e-62	219.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia,2NW14@237|Flavobacterium	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HKD3_k127_8200043_5	925409.KI911562_gene1308	5.614e-55	194.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,1ISAQ@117747|Sphingobacteriia	976|Bacteroidetes	S	MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
HKD3_k127_8200043_0	700598.Niako_3539	5.092e-146	471.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1IVXC@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD3_k127_8200043_1	929703.KE386491_gene196	2.96e-100	333.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,47MBV@768503|Cytophagia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
HKD3_k127_8206297_2	700598.Niako_3026	2.781e-127	407.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1IP50@117747|Sphingobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HKD3_k127_8206297_7	468059.AUHA01000006_gene2938	4.788e-21	100.0	2DSJJ@1|root,33GER@2|Bacteria,4NZAF@976|Bacteroidetes,1IZF5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8206297_0	743722.Sph21_3621	1.394e-190	604.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1IPIU@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
HKD3_k127_8206297_6	525373.HMPREF0766_10010	5.103e-71	249.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1IRSV@117747|Sphingobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
HKD3_k127_8206297_3	1123248.KB893320_gene3934	4.123e-124	407.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1IP03@117747|Sphingobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD3_k127_8206297_4	700598.Niako_4566	2.276e-79	271.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1IQV2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
HKD3_k127_8206297_5	1123248.KB893381_gene1043	2.14e-72	254.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose reductase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD3_k127_8206297_1	700598.Niako_0983	1.263e-127	416.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1IQ05@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
HKD3_k127_821857_1	468059.AUHA01000007_gene2663	1.84e-21	94.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IWQ3@117747|Sphingobacteriia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_821857_0	1237149.C900_02163	3.792e-120	396.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_82236_6	649349.Lbys_2150	0.000146	48.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47K8N@768503|Cytophagia	976|Bacteroidetes	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
HKD3_k127_82236_3	1123248.KB893323_gene1558	1.846e-60	212.0	2B1RZ@1|root,31U7Q@2|Bacteria,4NR0B@976|Bacteroidetes,1IYX1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_82236_5	1123278.KB893592_gene5973	1.693e-10	61.0	COG0657@1|root,COG0657@2|Bacteria,4PKKH@976|Bacteroidetes,47KC9@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
HKD3_k127_82236_1	485918.Cpin_7185	9.338e-78	265.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1ITKI@117747|Sphingobacteriia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
HKD3_k127_82236_0	929562.Emtol_3059	0.0	1045.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,47YKE@768503|Cytophagia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_82236_4	1185876.BN8_04535	7.296e-54	195.0	COG3637@1|root,COG3637@2|Bacteria,4PM31@976|Bacteroidetes,47KS5@768503|Cytophagia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_8224488_2	526227.Mesil_2803	2.467e-81	279.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
HKD3_k127_8224488_4	391596.PBAL39_20920	1.666e-50	187.0	COG0664@1|root,COG0664@2|Bacteria,4NM5E@976|Bacteroidetes,1ITAJ@117747|Sphingobacteriia	976|Bacteroidetes	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_8224488_3	1267211.KI669560_gene1637	3.581e-67	232.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1ISPY@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_8224488_0	1267211.KI669560_gene1636	0.0	1211.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1IQ1B@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome C oxidase subunit II, periplasmic domain	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_8224488_1	1267211.KI669560_gene1635	8.553e-99	327.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD3_k127_8285818_2	1123248.KB893359_gene2052	1.067e-22	103.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
HKD3_k127_8285818_1	1123248.KB893359_gene2053	3.744e-160	510.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD3_k127_8295580_1	929703.KE386491_gene4114	1.594e-264	829.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47JE7@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
HKD3_k127_8295580_0	1267211.KI669560_gene2871	0.0	1027.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_8295580_3	929556.Solca_3789	1.549e-24	110.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1ITMU@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
HKD3_k127_8295580_2	700598.Niako_6431	6.735e-249	784.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD3_k127_8295580_4	1123277.KB893175_gene1302	0.000146	48.0	COG1807@1|root,COG1807@2|Bacteria,4NIT6@976|Bacteroidetes,47K6Z@768503|Cytophagia	976|Bacteroidetes	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_8324402_0	1392488.JHZY01000004_gene3112	1.024e-55	200.0	COG0520@1|root,COG0520@2|Bacteria,4NM0W@976|Bacteroidetes,1I00M@117743|Flavobacteriia,2XJWU@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD3_k127_8324402_2	1178825.ALIH01000005_gene241	3.394e-25	107.0	COG1476@1|root,COG1476@2|Bacteria,4NV53@976|Bacteroidetes,1I527@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD3_k127_8324402_1	504472.Slin_0312	3.736e-27	115.0	2BTXK@1|root,32P5R@2|Bacteria,4NSMQ@976|Bacteroidetes,47R0Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8324402_3	1267211.KI669560_gene844	1.579e-16	81.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
HKD3_k127_8344711_2	991.IW20_23970	5.819e-130	422.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,1HWT3@117743|Flavobacteriia,2NSBP@237|Flavobacterium	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
HKD3_k127_8344711_1	1239962.C943_00987	9.924e-179	565.0	COG0252@1|root,COG0252@2|Bacteria,4NFKG@976|Bacteroidetes,47MY9@768503|Cytophagia	976|Bacteroidetes	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD3_k127_8344711_0	991.IW20_23975	7.385e-240	748.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,1IJ8C@117743|Flavobacteriia	976|Bacteroidetes	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD3_k127_8365697_0	925409.KI911562_gene1311	4.936e-221	709.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD3_k127_8365697_1	1454007.JAUG01000043_gene10	6.869e-20	92.0	2DV0V@1|root,33TES@2|Bacteria,4P1AE@976|Bacteroidetes,1IWVT@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD-like family	-	-	-	-	-	-	-	-	-	-	-	-	PKD_2
HKD3_k127_8366937_3	686340.Metal_1950	1.992e-09	60.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria,1XEQT@135618|Methylococcales	135618|Methylococcales	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
HKD3_k127_8366937_1	686340.Metal_1951	1.336e-122	398.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,1XEUX@135618|Methylococcales	135618|Methylococcales	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HKD3_k127_8366937_2	1123392.AQWL01000008_gene1207	1.127e-57	206.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2VRJE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HKD3_k127_8366937_0	697282.Mettu_3471	8.032e-318	980.0	COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
HKD3_k127_8373398_1	700598.Niako_1564	2.486e-98	331.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1INW8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
HKD3_k127_8373398_0	925409.KI911562_gene1811	1.676e-119	386.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1IP8P@117747|Sphingobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HKD3_k127_8373398_2	714943.Mucpa_3255	5.491e-25	108.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1IU82@117747|Sphingobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
HKD3_k127_8380067_2	1341155.FSS13T_20330	2.771e-08	59.0	294EW@1|root,2ZRUR@2|Bacteria,4NPA3@976|Bacteroidetes,1I5NJ@117743|Flavobacteriia,2NX0P@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
HKD3_k127_8380067_0	926562.Oweho_2057	2.357e-146	478.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,1HXNZ@117743|Flavobacteriia,2PAJP@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_8380067_1	1218108.KB908291_gene1027	1.276e-86	297.0	COG0596@1|root,COG0596@2|Bacteria,4PN81@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD3_k127_8388062_1	1123248.KB893316_gene4597	4.573e-27	115.0	28ME7@1|root,2ZARX@2|Bacteria,4P47D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_8388062_0	929713.NIASO_05150	1.392e-76	268.0	COG1917@1|root,COG1917@2|Bacteria,4NRZM@976|Bacteroidetes,1IYE8@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8388062_2	1123248.KB893348_gene293	5.335e-23	106.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_8432028_2	1123277.KB893182_gene4746	6.205e-18	83.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,47MN5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HKD3_k127_8432028_1	485918.Cpin_0871	2.151e-121	398.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1IR5U@117747|Sphingobacteriia	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
HKD3_k127_8432028_0	1121957.ATVL01000008_gene4124	8.268e-124	404.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47K89@768503|Cytophagia	976|Bacteroidetes	G	TIGRFAM glucose galactose transporter	gluP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
HKD3_k127_8435429_2	1185876.BN8_02228	0.0003623	51.0	COG1520@1|root,COG2374@1|root,COG1520@2|Bacteria,COG2374@2|Bacteria,4NJHN@976|Bacteroidetes,47Q1G@768503|Cytophagia	976|Bacteroidetes	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8435429_1	471854.Dfer_2120	1.133e-11	74.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,PPC,Peptidase_M36
HKD3_k127_8435429_0	1267211.KI669560_gene2032	4.926e-145	466.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1IRKN@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HKD3_k127_8439103_1	925409.KI911562_gene1225	3.991e-131	421.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1IP15@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_8439103_2	929713.NIASO_06440	1.065e-56	199.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Chaperonin Cpn10	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
HKD3_k127_8439103_0	700598.Niako_5604	0.0	1195.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD3_k127_844191_1	700598.Niako_2929	7.673e-144	460.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1INWM@117747|Sphingobacteriia	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
HKD3_k127_844191_5	926556.Echvi_3253	1.536e-42	166.0	COG0457@1|root,COG0457@2|Bacteria	926556.Echvi_3253|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_844191_4	926556.Echvi_3252	3.163e-55	201.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
HKD3_k127_844191_7	700598.Niako_2928	1.666e-24	108.0	2EWYR@1|root,346M6@2|Bacteria,4P5DU@976|Bacteroidetes,1IZAP@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
HKD3_k127_844191_3	925409.KI911562_gene2345	1.321e-74	254.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD3_k127_844191_0	700598.Niako_4610	0.0	1011.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HKD3_k127_844191_2	1123248.KB893326_gene1441	2.633e-137	444.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_844191_6	468059.AUHA01000005_gene2445	1.564e-31	127.0	COG2149@1|root,COG2149@2|Bacteria,4NW0X@976|Bacteroidetes,1IZG7@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
HKD3_k127_844191_8	1123278.KB893552_gene3738	3.259e-05	46.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47MX5@768503|Cytophagia	976|Bacteroidetes	P	Zn-dependent hydrolase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_8444924_3	929562.Emtol_1035	6.925e-43	158.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,47KD2@768503|Cytophagia	976|Bacteroidetes	CE	Isocitrate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_8444924_0	1279009.ADICEAN_03124	6.755e-129	418.0	COG0583@1|root,COG0583@2|Bacteria,4NGHS@976|Bacteroidetes,47M6G@768503|Cytophagia	976|Bacteroidetes	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_8444924_2	929713.NIASO_12980	1.751e-84	288.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes,1J13D@117747|Sphingobacteriia	976|Bacteroidetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HKD3_k127_8444924_1	1123248.KB893322_gene684	9.732e-87	292.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1INZC@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HKD3_k127_8458252_1	929556.Solca_2148	4.076e-115	406.0	COG3291@1|root,COG3291@2|Bacteria,4NI5F@976|Bacteroidetes,1IRIG@117747|Sphingobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,PKD
HKD3_k127_8458252_0	929556.Solca_2149	2.999e-153	516.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,1IP8Z@117747|Sphingobacteriia	976|Bacteroidetes	S	double-strand break repair	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8467474_1	929556.Solca_1050	9.014e-166	538.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1IRDG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_8467474_6	929713.NIASO_18385	1.113e-31	129.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,1ITH9@117747|Sphingobacteriia	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
HKD3_k127_8467474_5	929713.NIASO_18380	1.159e-35	142.0	COG5642@1|root,COG5642@2|Bacteria,4NX1V@976|Bacteroidetes,1IUEV@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
HKD3_k127_8467474_2	700598.Niako_4356	7.894e-153	497.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_8467474_0	925409.KI911562_gene1092	1.797e-246	777.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1IPN2@117747|Sphingobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HKD3_k127_8467474_4	1233951.IO90_06340	3.891e-40	151.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,1I2YA@117743|Flavobacteriia,3HI8G@358033|Chryseobacterium	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HKD3_k127_8467474_3	925409.KI911562_gene1607	2.286e-62	235.0	COG0810@1|root,COG0860@1|root,COG4219@1|root,COG0810@2|Bacteria,COG0860@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1IXPP@117747|Sphingobacteriia	976|Bacteroidetes	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Peptidase_M56,TonB_C
HKD3_k127_8467474_7	485918.Cpin_0813	2.624e-13	70.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1INKX@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD3_k127_8482499_0	700598.Niako_0469	1.095e-146	483.0	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1IQM7@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
HKD3_k127_8482499_4	1239962.C943_00778	9.332e-45	171.0	COG1652@1|root,COG1652@2|Bacteria,4NJV3@976|Bacteroidetes,47R3Z@768503|Cytophagia	976|Bacteroidetes	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8482499_3	1239962.C943_00780	2.835e-57	204.0	2DMQT@1|root,32T2H@2|Bacteria,4NN19@976|Bacteroidetes,47RJF@768503|Cytophagia	976|Bacteroidetes	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
HKD3_k127_8482499_2	929556.Solca_2157	3.036e-75	254.0	2DB76@1|root,2Z7JZ@2|Bacteria,4NQDC@976|Bacteroidetes,1ISNB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
HKD3_k127_8482499_1	177437.HRM2_13190	3.292e-100	332.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42NJI@68525|delta/epsilon subdivisions,2WJI8@28221|Deltaproteobacteria,2MPX9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
HKD3_k127_8514714_2	153721.MYP_4960	1.348e-64	223.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,47MMM@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_8514714_1	1341181.FLJC2902T_22310	3.985e-78	265.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,1I00Y@117743|Flavobacteriia,2NUNF@237|Flavobacterium	976|Bacteroidetes	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HKD3_k127_8514714_0	1237149.C900_02167	3.367e-95	319.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
HKD3_k127_8514714_3	1123248.KB893316_gene4664	7.678e-57	202.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_8529578_1	925409.KI911562_gene248	1.047e-121	396.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1IQ54@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HKD3_k127_8529578_0	925409.KI911562_gene249	9.92e-157	504.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IUW9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD3_k127_8541808_1	700598.Niako_7005	6.001e-102	338.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1IYWB@117747|Sphingobacteriia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
HKD3_k127_8541808_2	313606.M23134_02099	5.418e-60	214.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,47JIZ@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD3_k127_8541808_0	1123248.KB893315_gene3013	5.321e-120	395.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1J0PK@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_8544051_0	925409.KI911562_gene924	9.994e-234	728.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1IQ8E@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
HKD3_k127_8544051_2	714943.Mucpa_3378	2.601e-49	181.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1ITIM@117747|Sphingobacteriia	976|Bacteroidetes	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HKD3_k127_8544051_1	1443665.JACA01000011_gene1435	1.81e-187	593.0	COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,1HXIF@117743|Flavobacteriia,2YH0J@290174|Aquimarina	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_8550690_0	1123248.KB893321_gene484	1.31e-197	624.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPDG@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD3_k127_8550690_1	700598.Niako_1209	1.256e-141	464.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1IPUP@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
HKD3_k127_8572254_2	929703.KE386491_gene313	1.216e-06	50.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,47JNE@768503|Cytophagia	976|Bacteroidetes	E	argininosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD3_k127_8572254_1	700598.Niako_5688	4.196e-107	352.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IR6P@117747|Sphingobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_8572254_0	1089547.KB913013_gene3252	3.196e-260	820.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,47MJ2@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_8576136_1	929556.Solca_4204	2.42e-116	389.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1IRJE@117747|Sphingobacteriia	976|Bacteroidetes	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
HKD3_k127_8576136_0	1239962.C943_01002	0.0	1290.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD3_k127_8576136_2	929556.Solca_4206	1.966e-106	357.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,1INTJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HKD3_k127_8576136_5	1121904.ARBP01000013_gene309	4.003e-25	114.0	COG1226@1|root,32Y28@2|Bacteria	2|Bacteria	P	Ion transport 2 domain protein	RB9536	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
HKD3_k127_8576136_3	348824.LPU83_3753	6.393e-78	273.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,4BC1H@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_8576136_4	111781.Lepto7376_2918	2.314e-27	116.0	COG1017@1|root,COG1017@2|Bacteria,1G3MG@1117|Cyanobacteria,1H9R2@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	Globin,Pentapeptide
HKD3_k127_8583960_2	1267211.KI669560_gene1511	8.824e-18	90.0	28N01@1|root,2ZB6M@2|Bacteria,4NFN1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8583960_1	395495.Lcho_4245	3.7e-38	147.0	COG2940@1|root,COG2940@2|Bacteria,1RIQT@1224|Proteobacteria,2VT7F@28216|Betaproteobacteria,1KM5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD3_k127_8583960_0	504472.Slin_3371	2.168e-66	235.0	COG3228@1|root,COG3228@2|Bacteria,4NGM9@976|Bacteroidetes,47PJA@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
HKD3_k127_8583960_3	1123248.KB893338_gene2303	2.797e-16	79.0	2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,1IUQI@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
HKD3_k127_8595238_2	1267211.KI669560_gene2391	3.208e-08	59.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_8595238_0	880071.Fleli_3876	1.793e-220	694.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HKD3_k127_8595238_1	760192.Halhy_1891	2.166e-143	460.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IVF5@117747|Sphingobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD3_k127_8606479_3	471854.Dfer_5247	1.65e-29	130.0	COG1651@1|root,COG3271@1|root,COG4243@1|root,COG1651@2|Bacteria,COG3271@2|Bacteria,COG4243@2|Bacteria,4NH0U@976|Bacteroidetes,47M6I@768503|Cytophagia	976|Bacteroidetes	O	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Thioredoxin_4,VKOR
HKD3_k127_8606479_2	1239962.C943_01292	6.192e-51	188.0	2E3FB@1|root,32YE4@2|Bacteria,4P77I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8606479_1	1239962.C943_01293	3.35e-52	194.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD3_k127_8606479_0	468059.AUHA01000005_gene2450	3.022e-163	521.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IRNA@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD3_k127_8613452_0	1550091.JROE01000002_gene1119	7.62e-82	282.0	COG0644@1|root,COG0644@2|Bacteria,4PMBP@976|Bacteroidetes,1IQ1V@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HKD3_k127_8613452_1	927658.AJUM01000042_gene1500	2.336e-52	202.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565,SLH
HKD3_k127_861857_0	925409.KI911562_gene1107	7.539e-223	696.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
HKD3_k127_8620648_2	1267211.KI669560_gene2746	3.051e-62	221.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1IPM6@117747|Sphingobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
HKD3_k127_8620648_1	925409.KI911562_gene1304	2.824e-144	464.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1IW4H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
HKD3_k127_8620648_3	700598.Niako_2957	1.439e-47	180.0	2DNNM@1|root,32YAS@2|Bacteria,4NVE7@976|Bacteroidetes,1IZ48@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8620648_5	1123248.KB893385_gene4769	8.207e-31	126.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1IUC4@117747|Sphingobacteriia	976|Bacteroidetes	J	Class I peptide chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
HKD3_k127_8620648_0	929713.NIASO_18605	2.613e-150	484.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1IP38@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
HKD3_k127_8620648_4	925409.KI911562_gene1265	4.904e-37	145.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
HKD3_k127_8622674_1	1185876.BN8_02595	1.592e-56	198.0	COG5285@1|root,COG5285@2|Bacteria,4NG3B@976|Bacteroidetes,47N28@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
HKD3_k127_8622674_0	1123057.P872_07640	8.595e-144	463.0	COG0252@1|root,COG0252@2|Bacteria,4NFKG@976|Bacteroidetes,47MY9@768503|Cytophagia	976|Bacteroidetes	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD3_k127_8622674_2	760192.Halhy_5759	7.932e-24	107.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD3_k127_8631433_1	700598.Niako_6963	2.84e-78	262.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
HKD3_k127_8631433_0	1347342.BN863_32480	1.011e-185	611.0	COG4773@1|root,COG4773@2|Bacteria,4PKDX@976|Bacteroidetes,1HZ3P@117743|Flavobacteriia	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg
HKD3_k127_8631433_2	1250278.JQNQ01000001_gene1424	1.004e-27	121.0	2E380@1|root,31YMS@2|Bacteria,4NSEF@976|Bacteroidetes,1I3RR@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM Porphyromonas gingivalis paralogous family TIGR01200	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_8636741_0	1124780.ANNU01000006_gene2890	2.5e-54	212.0	COG1345@1|root,COG1345@2|Bacteria	2|Bacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02396,ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF1929,F5_F8_type_C,Flagellin_IN,Flagellin_N,Flg_bbr_C,LTD,Laminin_G_3,Peptidase_M6,TMP_2
HKD3_k127_8636741_1	77586.LPERR06G22500.1	0.0006046	45.0	KOG4658@1|root,KOG4658@2759|Eukaryota	2759|Eukaryota	S	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC
HKD3_k127_8644441_0	1123248.KB893359_gene2113	1.435e-180	577.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HKD3_k127_8644441_1	700598.Niako_6852	2.097e-128	414.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1IPP4@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD3_k127_8644441_3	700598.Niako_6851	3.714e-39	160.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,1IUMD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
HKD3_k127_8644441_2	1123248.KB893325_gene1158	2.287e-44	165.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1J0U3@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
HKD3_k127_8644868_7	700598.Niako_6995	1.921e-87	296.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,1J0KY@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8644868_5	1267211.KI669560_gene2330	8.682e-126	410.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1IQI3@117747|Sphingobacteriia	976|Bacteroidetes	E	Asparaginase	ybiK	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
HKD3_k127_8644868_6	700598.Niako_4928	1.907e-117	387.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
HKD3_k127_8644868_0	925409.KI911562_gene2815	1.573e-212	669.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1IPW4@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_8644868_10	1121890.AUDO01000007_gene2506	2.802e-30	127.0	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes	976|Bacteroidetes	O	alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_8644868_9	700598.Niako_4951	1.308e-42	174.0	COG0457@1|root,COG0457@2|Bacteria	700598.Niako_4951|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8644868_8	398720.MED217_13701	3.766e-87	297.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia,2XJDN@283735|Leeuwenhoekiella	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD3_k127_8644868_1	1267211.KI669560_gene2360	1.641e-193	606.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1IPW2@117747|Sphingobacteriia	976|Bacteroidetes	GM	NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_8644868_2	1089550.ATTH01000001_gene216	2.276e-182	580.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1FISV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD3_k127_8644868_3	700598.Niako_5028	1.073e-172	548.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1IQH3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_8644868_4	700598.Niako_5029	6.973e-137	449.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1IQKA@117747|Sphingobacteriia	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
HKD3_k127_8646179_1	1267211.KI669560_gene809	1.145e-183	587.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_8646179_10	1123248.KB893348_gene314	4.089e-54	198.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,1IT8X@117747|Sphingobacteriia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
HKD3_k127_8646179_8	313598.MED152_02565	6.048e-78	262.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1I1A9@117743|Flavobacteriia,3VWIH@52959|Polaribacter	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
HKD3_k127_8646179_4	1123248.KB893314_gene3610	2.014e-104	352.0	COG0644@1|root,COG0644@2|Bacteria,4NDTU@976|Bacteroidetes,1J0IB@117747|Sphingobacteriia	976|Bacteroidetes	C	Lycopene cyclase protein	crtY	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
HKD3_k127_8646179_12	1178825.ALIH01000005_gene241	1.163e-26	109.0	COG1476@1|root,COG1476@2|Bacteria,4NV53@976|Bacteroidetes,1I527@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD3_k127_8646179_13	509635.N824_25605	5.984e-20	95.0	2BTXK@1|root,328ER@2|Bacteria,4P9DB@976|Bacteroidetes,1IZV0@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8646179_6	1122605.KB893637_gene3288	8.24e-79	267.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
HKD3_k127_8646179_11	1123248.KB893324_gene1740	1.783e-39	151.0	COG4232@1|root,COG4232@2|Bacteria,4NQID@976|Bacteroidetes,1ISZ1@117747|Sphingobacteriia	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
HKD3_k127_8646179_0	1122605.KB893625_gene2088	4.864e-237	750.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1IQXN@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
HKD3_k127_8646179_5	1267211.KI669560_gene394	5.597e-93	311.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1IR8K@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HKD3_k127_8646179_7	925409.KI911562_gene409	4.505e-78	273.0	COG2017@1|root,COG2017@2|Bacteria,4NKUK@976|Bacteroidetes,1IYMB@117747|Sphingobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HKD3_k127_8646179_2	1123248.KB893321_gene471	3.373e-137	447.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD3_k127_8646179_3	1123248.KB893325_gene1159	4.168e-116	389.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD3_k127_8646179_9	1123248.KB893325_gene1158	1.043e-74	268.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1J0U3@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
HKD3_k127_8661019_1	700598.Niako_5731	5.238e-53	195.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_8661019_0	1123248.KB893359_gene2216	3.626e-201	653.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IRHX@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_8661019_2	760192.Halhy_5714	1.027e-11	66.0	COG0477@1|root,COG2814@2|Bacteria,4NEQU@976|Bacteroidetes,1IP74@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_8671609_3	1237149.C900_04940	2.918e-45	174.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_8671609_6	761193.Runsl_1483	2.154e-11	70.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_8671609_1	1267211.KI669560_gene693	1.888e-141	456.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,1INUS@117747|Sphingobacteriia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HKD3_k127_8671609_2	211165.AJLN01000116_gene3260	5.894e-70	243.0	COG0500@1|root,COG0500@2|Bacteria,1G4D6@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
HKD3_k127_8671609_4	700598.Niako_6432	1.049e-35	139.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1ITUM@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
HKD3_k127_8671609_5	700598.Niako_6433	7.509e-34	135.0	2DRKN@1|root,33C6H@2|Bacteria,4NZAT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8671609_0	700598.Niako_6434	5.744e-170	551.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
HKD3_k127_8683952_2	1123248.KB893317_gene4262	1.309e-24	103.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1IPD0@117747|Sphingobacteriia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD3_k127_8683952_1	388413.ALPR1_03725	6.434e-53	192.0	28NS2@1|root,2ZBR4@2|Bacteria,4NMBV@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8683952_0	929713.NIASO_04055	1.791e-73	252.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1IS2U@117747|Sphingobacteriia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
HKD3_k127_8683952_3	1183377.Py04_0737	6.233e-07	61.0	COG1572@1|root,arCOG07086@2157|Archaea,2Y2HS@28890|Euryarchaeota,2436N@183968|Thermococci	183968|Thermococci	G	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
HKD3_k127_870055_4	1304284.L21TH_2701	2.796e-45	166.0	COG0073@1|root,COG0073@2|Bacteria,1V6N9@1239|Firmicutes,24JJZ@186801|Clostridia,36K08@31979|Clostridiaceae	186801|Clostridia	J	PFAM t-RNA-binding domain protein	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
HKD3_k127_870055_1	700598.Niako_1602	9.583e-55	196.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1ITF8@117747|Sphingobacteriia	976|Bacteroidetes	F	cytidine and deoxycytidylate deaminase	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD3_k127_870055_0	1123248.KB893316_gene4625	1.918e-216	683.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD3_k127_870055_3	1123248.KB893316_gene4624	7.832e-52	194.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1IS5U@117747|Sphingobacteriia	976|Bacteroidetes	K	MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
HKD3_k127_870055_2	700598.Niako_1599	6.752e-52	185.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD3_k127_8705060_0	700598.Niako_0168	3.255e-103	339.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HKD3_k127_8705060_2	700598.Niako_0167	6.341e-97	323.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_8705060_1	700598.Niako_5542	9.015e-98	326.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1IQ48@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HKD3_k127_8705060_3	1123248.KB893321_gene562	3.05e-67	236.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1ISMS@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_8705060_4	1122605.KB893648_gene3613	1.288e-05	48.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
HKD3_k127_8714386_3	700598.Niako_2565	1.065e-111	364.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
HKD3_k127_8714386_0	700598.Niako_0416	2.731e-131	426.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_8714386_5	925409.KI911562_gene2572	3.068e-55	198.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD3_k127_8714386_4	259536.Psyc_0278	8.178e-61	216.0	COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,1S2UY@1236|Gammaproteobacteria,3NKSF@468|Moraxellaceae	1236|Gammaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_8714386_2	925409.KI911562_gene2122	1.488e-113	381.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1IQ7X@117747|Sphingobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
HKD3_k127_8714386_6	1123248.KB893370_gene5081	1.793e-36	140.0	COG3063@1|root,COG3063@2|Bacteria,4PKQM@976|Bacteroidetes,1J0N6@117747|Sphingobacteriia	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HKD3_k127_8714386_1	700598.Niako_4139	3.484e-118	385.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1IQTX@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD3_k127_8714386_7	485918.Cpin_3759	7.732e-07	52.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HKD3_k127_8728915_0	1123248.KB893348_gene192	3.591e-82	281.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IXJN@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8728915_1	700598.Niako_0927	5.904e-45	169.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_8755882_0	925409.KI911562_gene1311	4.138e-192	618.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD3_k127_8755882_1	700598.Niako_3084	2.855e-135	450.0	2DV0V@1|root,33TES@2|Bacteria,4P1AE@976|Bacteroidetes,1IWVT@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD-like family	-	-	-	-	-	-	-	-	-	-	-	-	PKD_2
HKD3_k127_8757072_0	925409.KI911562_gene1393	5.346e-263	818.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IPYF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	kojP	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
HKD3_k127_8757072_1	1267211.KI669560_gene1004	1.772e-198	625.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_8759678_0	1123248.KB893332_gene2256	1.263e-222	699.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1IP8R@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD3_k127_8766058_4	1123248.KB893331_gene3752	3.689e-23	99.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1IQ7Q@117747|Sphingobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD3_k127_8766058_1	761193.Runsl_0031	3.334e-165	531.0	COG0463@1|root,COG0560@1|root,COG0463@2|Bacteria,COG0560@2|Bacteria,4NHAG@976|Bacteroidetes,47RYN@768503|Cytophagia	976|Bacteroidetes	EM	Putative Phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
HKD3_k127_8766058_2	700598.Niako_6078	3.892e-106	351.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1IRSU@117747|Sphingobacteriia	976|Bacteroidetes	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD3_k127_8766058_0	925409.KI911562_gene724	0.0	1040.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1IV6E@117747|Sphingobacteriia	976|Bacteroidetes	CI	MaoC like domain	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
HKD3_k127_8766058_5	700598.Niako_4444	8.963e-12	75.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_8766058_3	700598.Niako_6072	3.358e-33	129.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISB0@117747|Sphingobacteriia	976|Bacteroidetes	O	methionine sulfoxide reductase	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HKD3_k127_8792696_0	1123248.KB893314_gene3624	6.653e-244	761.0	COG0443@1|root,COG0443@2|Bacteria,4NEHZ@976|Bacteroidetes,1IQ1C@117747|Sphingobacteriia	976|Bacteroidetes	O	heat shock protein 70	-	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
HKD3_k127_8793487_2	700598.Niako_5077	9.521e-64	222.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD3_k127_8793487_3	929713.NIASO_19250	5.596e-38	151.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes,1IT1C@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_8793487_0	700598.Niako_5094	2.894e-246	768.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1IPBW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HKD3_k127_8793487_1	1123248.KB893320_gene3871	2.349e-124	406.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
HKD3_k127_879876_3	925409.KI911562_gene2993	5.314e-51	194.0	COG0683@1|root,COG0683@2|Bacteria,4PMPE@976|Bacteroidetes,1ISIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
HKD3_k127_879876_0	700598.Niako_0180	3.088e-89	297.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IST6@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HKD3_k127_879876_2	925409.KI911562_gene72	2.451e-70	245.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1IP9T@117747|Sphingobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD3_k127_879876_1	929713.NIASO_03225	1.182e-71	246.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD3_k127_8805741_2	1122179.KB890436_gene1406	1.768e-35	147.0	COG1836@1|root,COG1836@2|Bacteria,4NPN7@976|Bacteroidetes,1IUFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
HKD3_k127_8805741_3	313606.M23134_06811	5.057e-30	129.0	298PG@1|root,2ZVTY@2|Bacteria,4NP4F@976|Bacteroidetes,47PR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8805741_1	1487953.JMKF01000045_gene2916	5.384e-56	207.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria,1H8PU@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM UbiA prenyltransferase	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
HKD3_k127_8805741_0	1267211.KI669560_gene1308	3.257e-68	234.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_8809902_1	1239962.C943_00981	6.178e-104	342.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8809902_5	1121875.KB907556_gene612	5.465e-34	138.0	2E5SP@1|root,330H2@2|Bacteria,4P4B3@976|Bacteroidetes	976|Bacteroidetes	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
HKD3_k127_8809902_0	314278.NB231_01773	0.0	1226.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1WWMT@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_8809902_3	1121904.ARBP01000018_gene2685	1.988e-67	240.0	2E74W@1|root,331P9@2|Bacteria,4P4VB@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_8809902_2	1121875.KB907547_gene2995	2.853e-82	281.0	COG2067@1|root,COG2067@2|Bacteria,4NX18@976|Bacteroidetes,1I5D9@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8809902_6	1506583.JQJY01000008_gene4026	1.031e-30	129.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,1I22Y@117743|Flavobacteriia,2NVTZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_8809902_7	926556.Echvi_2174	6.63e-21	98.0	2CWBN@1|root,32SZD@2|Bacteria,4NU6S@976|Bacteroidetes,47VSE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8809902_8	113395.AXAI01000005_gene3889	1.734e-06	56.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HKD3_k127_8825305_2	1121904.ARBP01000001_gene5494	1.008e-28	127.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
HKD3_k127_8825305_0	925409.KI911562_gene873	3.415e-177	558.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1IR3A@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD3_k127_8825305_1	1123248.KB893319_gene3981	1.651e-84	282.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_8830433_2	1122179.KB890455_gene3038	2.327e-60	214.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes	976|Bacteroidetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_8830433_1	1267211.KI669560_gene1001	6.575e-166	529.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1IQPQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HKD3_k127_8830433_0	762903.Pedsa_0636	6.512e-172	544.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,1IRGT@117747|Sphingobacteriia	976|Bacteroidetes	C	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
HKD3_k127_8830433_3	537011.PREVCOP_06330	5.421e-15	75.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_8882903_1	925409.KI911562_gene2886	1.344e-245	790.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_8882903_2	925409.KI911562_gene2887	1.208e-92	310.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1IQ1X@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
HKD3_k127_8882903_0	1267211.KI669560_gene2007	3.357e-278	865.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1IQYY@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD3_k127_8882903_3	1123248.KB893330_gene395	2.219e-77	270.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1IXKD@117747|Sphingobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
HKD3_k127_8889007_1	1123248.KB893381_gene1025	4.969e-53	189.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1IP4J@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HKD3_k127_8889007_0	1123248.KB893381_gene1020	1.52e-214	682.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1IQAZ@117747|Sphingobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
HKD3_k127_8889007_2	700598.Niako_4706	1.736e-25	114.0	2DS3S@1|root,33EDT@2|Bacteria,4NY8U@976|Bacteroidetes,1IUQ6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8894390_2	1123276.KB893255_gene1880	2.084e-29	117.0	COG0346@1|root,COG0346@2|Bacteria,4NQCJ@976|Bacteroidetes,47QR5@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_8894390_1	700598.Niako_5195	4.973e-51	185.0	COG1680@1|root,COG1680@2|Bacteria,4NQF7@976|Bacteroidetes,1IYXK@117747|Sphingobacteriia	976|Bacteroidetes	V	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_8894390_0	1267211.KI669560_gene2464	9.945e-96	319.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_8924439_2	592029.DDD_3455	2.758e-37	146.0	COG3555@1|root,COG3555@2|Bacteria,4NN9Y@976|Bacteroidetes,1HXP8@117743|Flavobacteriia	976|Bacteroidetes	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
HKD3_k127_8924439_1	925409.KI911562_gene2109	1.462e-46	171.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
HKD3_k127_8924439_0	925409.KI911562_gene2108	6.733e-55	200.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1IV0I@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_8949585_1	760192.Halhy_1248	9.598e-205	648.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,1IP7E@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3533 conserved	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
HKD3_k127_8949585_6	313606.M23134_07852	1.125e-24	108.0	COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,47R7P@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_8949585_0	761193.Runsl_3167	0.0	1176.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KPV@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD3_k127_8949585_4	313596.RB2501_01016	2.035e-73	250.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1I17D@117743|Flavobacteriia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD3_k127_8949585_5	1122621.ATZA01000035_gene3612	1.12e-59	210.0	COG1917@1|root,COG1917@2|Bacteria,4NR0K@976|Bacteroidetes,1IT3Z@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_8949585_2	1168034.FH5T_18155	5.261e-163	518.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,2FMYE@200643|Bacteroidia	976|Bacteroidetes	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_8949585_3	760192.Halhy_0714	1.896e-121	393.0	COG2207@1|root,COG2207@2|Bacteria,4NDYY@976|Bacteroidetes,1IQRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_8978296_1	700598.Niako_5160	3.847e-131	422.0	COG1319@1|root,COG1319@2|Bacteria,4NFT8@976|Bacteroidetes,1IV94@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
HKD3_k127_8978296_2	1185876.BN8_01630	6.497e-23	104.0	COG4430@1|root,COG4430@2|Bacteria,4NW07@976|Bacteroidetes,47RVU@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
HKD3_k127_8978296_0	1239962.C943_00095	3.335e-148	476.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47NWH@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	pbpE	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
HKD3_k127_8979946_2	1434325.AZQN01000008_gene2924	0.000194	46.0	COG0662@1|root,COG0662@2|Bacteria,4NNWT@976|Bacteroidetes,47Q0Y@768503|Cytophagia	976|Bacteroidetes	G	PFAM Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
HKD3_k127_8979946_0	929562.Emtol_2762	4.708e-79	269.0	COG2755@1|root,COG2755@2|Bacteria,4NHWJ@976|Bacteroidetes,47NGU@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_8979946_1	929713.NIASO_17725	1.035e-72	257.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1IRKY@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_9020285_1	925409.KI911562_gene1611	4.201e-74	254.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1IRTF@117747|Sphingobacteriia	976|Bacteroidetes	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
HKD3_k127_9020285_0	700598.Niako_4525	8.708e-161	514.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1IPSH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9048022_1	1286632.P278_02410	2.837e-40	152.0	COG1409@1|root,COG1409@2|Bacteria,4NI6R@976|Bacteroidetes,1I2P8@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_9048022_3	743722.Sph21_0827	5.387e-22	97.0	COG1373@1|root,COG1373@2|Bacteria,4NHQG@976|Bacteroidetes,1IS38@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
HKD3_k127_9048022_2	1034807.FBFL15_2521	1.682e-25	118.0	COG2378@1|root,COG2378@2|Bacteria,4NI15@976|Bacteroidetes,1HZYZ@117743|Flavobacteriia,2P04R@237|Flavobacterium	976|Bacteroidetes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
HKD3_k127_9048022_0	866536.Belba_0510	1.533e-86	291.0	COG1479@1|root,COG1479@2|Bacteria,4NKIC@976|Bacteroidetes,47SZ2@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
HKD3_k127_915805_0	1267211.KI669560_gene1663	6.171e-161	513.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1IQSA@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
HKD3_k127_915805_1	700598.Niako_0369	9.375e-66	239.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1IT79@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD3_k127_915805_2	1122605.KB893627_gene2918	7.871e-45	163.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD3_k127_9161187_0	1123248.KB893345_gene31	1.159e-259	809.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1IQSQ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HKD3_k127_9186250_10	1454007.JAUG01000055_gene3308	3.385e-26	108.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_9186250_1	700598.Niako_0329	5.078e-229	714.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1IR18@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HKD3_k127_9186250_5	925409.KI911562_gene2787	3.602e-109	361.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1INM6@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD3_k127_9186250_8	925409.KI911562_gene2788	5.793e-51	189.0	COG1983@1|root,COG1983@2|Bacteria,4PKK1@976|Bacteroidetes,1J0YH@117747|Sphingobacteriia	976|Bacteroidetes	KT	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_9186250_0	1123248.KB893359_gene2108	1.902e-262	830.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,1J0SA@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_9186250_9	1267211.KI669560_gene2295	1.889e-37	144.0	COG0607@1|root,COG0607@2|Bacteria,4NVM6@976|Bacteroidetes,1IZ3G@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_9186250_6	1123248.KB893385_gene4812	7.662e-76	263.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1ISPM@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
HKD3_k127_9186250_3	700598.Niako_0318	1.259e-135	441.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1INQY@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD3_k127_9186250_7	485918.Cpin_5947	2.198e-66	228.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1J0P2@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
HKD3_k127_9186250_4	700598.Niako_0315	1.554e-113	375.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1IQ3K@117747|Sphingobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
HKD3_k127_9186250_2	1123248.KB893329_gene4475	6.812e-190	606.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_9187451_0	700598.Niako_5718	1.791e-158	505.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1IQ8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
HKD3_k127_9187451_1	929713.NIASO_14230	5.791e-103	349.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HKD3_k127_9187451_2	700598.Niako_5720	6.615e-101	336.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1ISWJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
HKD3_k127_9208786_2	1120965.AUBV01000004_gene1037	2.982e-60	218.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
HKD3_k127_9208786_0	1137281.D778_00504	3.561e-145	467.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
HKD3_k127_9208786_3	1131812.JQMS01000001_gene1669	6.062e-40	159.0	COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,1I32P@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_9208786_1	1189619.pgond44_14053	7.094e-134	431.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia	976|Bacteroidetes	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
HKD3_k127_9227249_4	471854.Dfer_2529	8.041e-12	66.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria,4PM4Q@976|Bacteroidetes	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_9227249_1	1185876.BN8_00056	5.012e-87	294.0	COG3279@1|root,COG3279@2|Bacteria,4NH5N@976|Bacteroidetes,47N4M@768503|Cytophagia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_9227249_0	1166018.FAES_1655	5.803e-211	691.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_9227249_2	471854.Dfer_3029	4.968e-40	164.0	COG3209@1|root,COG3209@2|Bacteria,4PKW4@976|Bacteroidetes,47Y7S@768503|Cytophagia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_9227249_3	1166018.FAES_1655	2.57e-38	158.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_9236227_2	391598.FBBAL38_11334	2.199e-07	52.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD3_k127_9236227_0	1123248.KB893337_gene2516	1.245e-185	602.0	COG3291@1|root,COG3291@2|Bacteria,4NV8C@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD3_k127_9236227_1	471854.Dfer_1965	6.717e-116	381.0	COG0024@1|root,COG0024@2|Bacteria,4NEAT@976|Bacteroidetes,47KJV@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD3_k127_9237912_3	945713.IALB_2303	1.175e-08	55.0	2DS1S@1|root,33E5G@2|Bacteria	2|Bacteria	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
HKD3_k127_9237912_1	1123248.KB893321_gene501	8.796e-182	591.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1IQJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Outer membrane cobalamin receptor protein	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
HKD3_k127_9237912_0	700598.Niako_6842	2.527e-196	642.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1INX6@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HKD3_k127_9237912_2	760192.Halhy_2531	1.577e-139	452.0	COG0531@1|root,COG0531@2|Bacteria,4NICM@976|Bacteroidetes,1IQNC@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_9251274_3	1267211.KI669560_gene2084	0.0002699	44.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HKD3_k127_9251274_1	1122605.KB893647_gene486	7.752e-29	125.0	2DQH4@1|root,336TE@2|Bacteria,4NXA3@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
HKD3_k127_9251274_0	1123248.KB893314_gene3304	1.035e-118	386.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1IP59@117747|Sphingobacteriia	976|Bacteroidetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD3_k127_9259246_2	762903.Pedsa_0804	8.93e-05	47.0	COG3266@1|root,COG4677@1|root,COG4733@1|root,COG3266@2|Bacteria,COG4677@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	pilL	-	1.11.1.5,3.2.1.51,4.2.2.2	ko:K00428,ko:K01728,ko:K02487,ko:K10297,ko:K15923,ko:K20276	ko00040,ko00511,ko02020,ko02024,map00040,map00511,map02020,map02024	M00507	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko04121	-	GH95	-	Beta_helix
HKD3_k127_9259246_1	700598.Niako_4482	2.295e-23	100.0	COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,1IUHT@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
HKD3_k127_9259246_0	1267211.KI669560_gene1859	0.0	1329.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HKD3_k127_9317323_2	1144313.PMI10_02610	1.642e-63	224.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1I040@117743|Flavobacteriia,2NUS5@237|Flavobacterium	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HKD3_k127_9317323_1	485918.Cpin_5583	1.033e-106	354.0	COG1305@1|root,COG1305@2|Bacteria,4NF4N@976|Bacteroidetes,1IPWA@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG1305 Transglutaminase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
HKD3_k127_9317323_0	1267211.KI669560_gene1276	1.239e-195	618.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD3_k127_9317323_3	1123248.KB893329_gene4443	1.242e-23	102.0	COG1119@1|root,COG1119@2|Bacteria,4NEWY@976|Bacteroidetes,1INTA@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
HKD3_k127_9327328_1	700598.Niako_5156	5.196e-140	450.0	COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes,1IW28@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ATPase associated with various cellular activities AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
HKD3_k127_9327328_0	700598.Niako_5155	4.744e-156	501.0	COG3552@1|root,COG3552@2|Bacteria,4NK40@976|Bacteroidetes,1IWRV@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
HKD3_k127_9327328_2	1123228.AUIH01000004_gene1087	1.098e-65	238.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,1MWFN@1224|Proteobacteria,1RV4F@1236|Gammaproteobacteria,1XQ7H@135619|Oceanospirillales	135619|Oceanospirillales	O	XdhC Rossmann domain	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
HKD3_k127_9327328_3	700598.Niako_5153	5.694e-10	61.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HKD3_k127_9358254_0	1267211.KI669560_gene17	7.492e-106	348.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD3_k127_9358254_1	1123248.KB893348_gene304	9.762e-101	342.0	COG3206@1|root,COG3206@2|Bacteria,4P3QF@976|Bacteroidetes	976|Bacteroidetes	M	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
HKD3_k127_9358254_3	1121899.Q764_01850	1.487e-31	136.0	2AFQQ@1|root,315SK@2|Bacteria,4NS2X@976|Bacteroidetes,1I3KK@117743|Flavobacteriia,2NU14@237|Flavobacterium	976|Bacteroidetes	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
HKD3_k127_9358254_2	485917.Phep_4180	4.001e-64	233.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1IX5B@117747|Sphingobacteriia	976|Bacteroidetes	L	UvrD-like helicase C-terminal domain	addA	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HKD3_k127_9381551_0	468059.AUHA01000002_gene536	2.286e-231	728.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1IP91@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_9381551_1	925409.KI911562_gene1257	9.121e-137	447.0	2BX9T@1|root,2Z83P@2|Bacteria,4NFAA@976|Bacteroidetes,1INWI@117747|Sphingobacteriia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_9381551_2	1123248.KB893359_gene2068	8.073e-133	432.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,1IQSZ@117747|Sphingobacteriia	976|Bacteroidetes	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD3_k127_9381551_3	700598.Niako_0948	6.157e-35	138.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
HKD3_k127_9435763_0	172088.AUGA01000016_gene2484	1.983e-90	320.0	COG1409@1|root,COG1409@2|Bacteria,1RHP4@1224|Proteobacteria,2U9B6@28211|Alphaproteobacteria,3K0V6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_9435763_1	700598.Niako_5634	3.45e-82	279.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1IRI4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
HKD3_k127_9449550_2	1121481.AUAS01000007_gene937	5.898e-23	101.0	COG4198@1|root,COG4198@2|Bacteria,4NI11@976|Bacteroidetes,47NFX@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like
HKD3_k127_9449550_0	700598.Niako_3960	0.0	1057.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1IPSI@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
HKD3_k127_9449550_3	1392498.JQLH01000001_gene591	2.558e-16	83.0	COG2827@1|root,COG2827@2|Bacteria,4NX4N@976|Bacteroidetes,1I5KU@117743|Flavobacteriia,2PITE@252356|Maribacter	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD3_k127_9449550_1	883096.HMPREF9699_02059	5.823e-29	122.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
HKD3_k127_9454592_2	1304874.JAFY01000005_gene1370	9.885e-69	239.0	COG3259@1|root,COG3259@2|Bacteria,3TAE4@508458|Synergistetes	508458|Synergistetes	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
HKD3_k127_9454592_5	926569.ANT_09670	1.338e-46	174.0	COG1941@1|root,COG1941@2|Bacteria,2G6MH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.12.1.2,1.8.98.5	ko:K14128,ko:K18007	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
HKD3_k127_9454592_1	383372.Rcas_1366	4.187e-89	299.0	COG3383@1|root,COG3383@2|Bacteria,2G65A@200795|Chloroflexi,3769N@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,NADH-G_4Fe-4S_3
HKD3_k127_9454592_0	926569.ANT_12520	2.346e-213	676.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	hoxF	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
HKD3_k127_9454592_4	653733.Selin_1982	1.326e-49	181.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	hoxE	-	1.6.5.3	ko:K00334,ko:K05586	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HKD3_k127_9454592_3	1279009.ADICEAN_03993	1.261e-59	222.0	COG2312@1|root,COG2312@2|Bacteria,4NKTN@976|Bacteroidetes,47QJ3@768503|Cytophagia	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
HKD3_k127_9456800_0	929556.Solca_2140	3.111e-135	441.0	COG0464@1|root,COG0464@2|Bacteria,4NFWG@976|Bacteroidetes,1IR7U@117747|Sphingobacteriia	976|Bacteroidetes	O	AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
HKD3_k127_9456800_1	313606.M23134_07653	9.049e-15	83.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LGT
HKD3_k127_9456800_2	316067.Geob_3744	4.569e-14	72.0	COG4942@1|root,COG4942@2|Bacteria,1R4AE@1224|Proteobacteria	1224|Proteobacteria	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9470929_3	531844.FIC_01525	8.084e-72	252.0	28MFR@1|root,2ZAT4@2|Bacteria,4NM07@976|Bacteroidetes	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
HKD3_k127_9470929_1	1267211.KI669560_gene1248	6.075e-167	539.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1IPKS@117747|Sphingobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_9470929_0	1267211.KI669560_gene1247	0.0	1167.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IP84@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_9470929_2	700598.Niako_6108	4.952e-81	284.0	COG3712@1|root,COG3712@2|Bacteria,4NM0I@976|Bacteroidetes	976|Bacteroidetes	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_9470929_4	700598.Niako_6109	4.335e-46	172.0	COG1595@1|root,COG1595@2|Bacteria,4NR0P@976|Bacteroidetes,1J0AP@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_9470929_5	655815.ZPR_0151	5.33e-08	61.0	COG2827@1|root,COG2827@2|Bacteria,4NW73@976|Bacteroidetes,1I5Z9@117743|Flavobacteriia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD3_k127_947151_3	714943.Mucpa_5245	6.348e-88	291.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1IPFW@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0374 Ni Fe-hydrogenase I large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
HKD3_k127_947151_1	700598.Niako_1264	8.569e-198	621.0	COG1740@1|root,COG1740@2|Bacteria,4NK1F@976|Bacteroidetes,1IRKT@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1740 Ni Fe-hydrogenase I small subunit	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
HKD3_k127_947151_4	714943.Mucpa_5247	1.721e-33	132.0	COG0375@1|root,COG0375@2|Bacteria,4NWR5@976|Bacteroidetes,1ITXG@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0375 Zn finger protein HypA HybF (possibly regulating hydrogenase expression)	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
HKD3_k127_947151_2	714943.Mucpa_5248	1.461e-93	317.0	COG0378@1|root,COG0378@2|Bacteria,4NJ0P@976|Bacteroidetes,1IR6X@117747|Sphingobacteriia	976|Bacteroidetes	KO	COGs COG0378 Ni2 -binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
HKD3_k127_947151_0	700598.Niako_1268	4.157e-224	718.0	COG0068@1|root,COG0068@2|Bacteria,4NIZ1@976|Bacteroidetes,1IRM2@117747|Sphingobacteriia	976|Bacteroidetes	O	TIGRFAM NiFe hydrogenase maturation protein HypF	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
HKD3_k127_947151_5	700598.Niako_1269	7.299e-31	124.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes,1IUA2@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Hydrogenase expression formation protein, HupF HypC	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
HKD3_k127_9482448_2	929562.Emtol_0926	3.992e-53	192.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,47K7D@768503|Cytophagia	976|Bacteroidetes	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_9482448_5	1550091.JROE01000005_gene2210	2.838e-28	123.0	COG3637@1|root,COG3637@2|Bacteria,4NRZA@976|Bacteroidetes,1ISQI@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_9482448_1	1123248.KB893332_gene2245	6.949e-65	225.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1IS01@117747|Sphingobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD3_k127_9482448_3	1123248.KB893332_gene2244	4.599e-49	182.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1ISWH@117747|Sphingobacteriia	976|Bacteroidetes	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HKD3_k127_9482448_0	1267211.KI669560_gene2793	3.059e-69	241.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1ISJU@117747|Sphingobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HKD3_k127_9482448_4	929713.NIASO_14145	2.95e-46	178.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_9489132_1	700598.Niako_4516	1.841e-119	396.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1IP8V@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HKD3_k127_9489132_2	929713.NIASO_00310	1.522e-108	358.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1ISQ1@117747|Sphingobacteriia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD3_k127_9489132_0	925409.KI911562_gene2779	1.634e-136	439.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1INX0@117747|Sphingobacteriia	976|Bacteroidetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
HKD3_k127_9489132_3	700598.Niako_4513	1.862e-17	89.0	2F5WP@1|root,33YFF@2|Bacteria,4P47E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9544128_1	929556.Solca_3548	5.721e-36	143.0	COG0457@1|root,COG0457@2|Bacteria,4PPB4@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9544128_0	929713.NIASO_17855	2.303e-205	641.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
HKD3_k127_9549010_6	1123278.KB893548_gene4716	1.576e-41	159.0	COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,47PSM@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
HKD3_k127_9549010_1	700598.Niako_6863	5.254e-261	811.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1INQA@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HKD3_k127_9549010_3	925409.KI911562_gene1174	8.024e-123	400.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD3_k127_9549010_8	929713.NIASO_19370	8.765e-38	145.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1IZAC@117747|Sphingobacteriia	976|Bacteroidetes	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
HKD3_k127_9549010_7	1123278.KB893577_gene1326	5.771e-41	156.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
HKD3_k127_9549010_2	485918.Cpin_6930	6.228e-234	735.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HKD3_k127_9549010_5	925409.KI911562_gene2747	4.198e-45	177.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes	976|Bacteroidetes	I	PFAM Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
HKD3_k127_9549010_0	929556.Solca_1442	3.189e-279	865.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1IVYE@117747|Sphingobacteriia	976|Bacteroidetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD3_k127_9549010_4	700598.Niako_6869	2.19e-71	243.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IP88@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD3_k127_9568457_7	700598.Niako_6876	7.397e-15	77.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1INPB@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HKD3_k127_9568457_0	925409.KI911562_gene361	4.492e-224	717.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD3_k127_9568457_6	760192.Halhy_1066	2.85e-41	160.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,1ITXI@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_9568457_4	1166018.FAES_3057	1.535e-66	233.0	COG0664@1|root,COG0664@2|Bacteria,4NN09@976|Bacteroidetes,47PAQ@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_9568457_5	1123248.KB893314_gene3431	4.259e-52	189.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9568457_3	1123248.KB893314_gene3432	1.491e-69	245.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,1IPE1@117747|Sphingobacteriia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HKD3_k127_9568457_1	700598.Niako_6872	1.088e-209	653.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1IPMZ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD3_k127_9568457_2	700598.Niako_6870	2.898e-85	286.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD3_k127_9580082_2	700598.Niako_1990	5.329e-70	243.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1IPJH@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HKD3_k127_9580082_1	925409.KI911562_gene1790	2.828e-81	274.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
HKD3_k127_9580082_0	1267211.KI669560_gene2232	2.788e-94	312.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
HKD3_k127_9600825_0	762903.Pedsa_0022	8.648e-148	476.0	COG0477@1|root,COG2814@2|Bacteria,4NG5F@976|Bacteroidetes	976|Bacteroidetes	EGP	Psort location CytoplasmicMembrane, score 10.00	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
HKD3_k127_9600825_1	1267211.KI669560_gene472	9.626e-108	359.0	COG0644@1|root,COG0644@2|Bacteria,4PMBP@976|Bacteroidetes,1IQ1V@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HKD3_k127_9612890_6	1123248.KB893320_gene3890	6.347e-12	68.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_9612890_1	929713.NIASO_11120	3.286e-116	379.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
HKD3_k127_9612890_5	1166018.FAES_4525	5.877e-57	207.0	2DBMF@1|root,2Z9YG@2|Bacteria,4NPRW@976|Bacteroidetes,47Q6I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9612890_4	925409.KI911562_gene2809	1.472e-66	233.0	COG2849@1|root,COG2849@2|Bacteria,4NZNQ@976|Bacteroidetes	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD3_k127_9612890_0	1267211.KI669560_gene2060	0.0	1053.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IV0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
HKD3_k127_9612890_3	925409.KI911562_gene2277	2.796e-71	244.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_9612890_2	1550091.JROE01000017_gene3765	2.912e-86	302.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
HKD3_k127_9624077_0	1123248.KB893314_gene3477	1.287e-73	253.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1IPQM@117747|Sphingobacteriia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HKD3_k127_9624077_1	1408473.JHXO01000013_gene564	7.635e-40	153.0	COG3610@1|root,COG3610@2|Bacteria,4NU0J@976|Bacteroidetes,2FPKT@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
HKD3_k127_9624077_2	1408473.JHXO01000013_gene563	1.083e-27	114.0	COG2966@1|root,COG2966@2|Bacteria,4NIU3@976|Bacteroidetes,2G2IZ@200643|Bacteroidia	976|Bacteroidetes	S	COGs COG2966 conserved	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
HKD3_k127_9626676_1	485917.Phep_2024	1.013e-81	284.0	COG1215@1|root,COG1215@2|Bacteria,4NJKY@976|Bacteroidetes,1IWJK@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_9626676_0	760192.Halhy_6846	2.702e-144	464.0	COG3329@1|root,COG3329@2|Bacteria,4NIR4@976|Bacteroidetes,1IW46@117747|Sphingobacteriia	976|Bacteroidetes	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
HKD3_k127_9626676_3	929556.Solca_1319	5.546e-49	184.0	COG1266@1|root,COG1266@2|Bacteria,4NPEG@976|Bacteroidetes,1IUFC@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_9626676_2	1123234.AUKI01000021_gene927	9.774e-76	263.0	COG0730@1|root,COG0730@2|Bacteria,4NKE8@976|Bacteroidetes,1II62@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_9626676_4	391596.PBAL39_05578	8.983e-16	78.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IP7Q@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_S41,Tricorn_C1
HKD3_k127_9627323_5	1123248.KB893348_gene269	2.298e-60	213.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1IQ5S@117747|Sphingobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
HKD3_k127_9627323_2	700598.Niako_6630	1.326e-145	468.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1IVKB@117747|Sphingobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
HKD3_k127_9627323_4	90814.KL370891_gene30	1.878e-68	240.0	COG0406@1|root,COG0406@2|Bacteria,1N8GN@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
HKD3_k127_9627323_1	925409.KI911562_gene612	5.081e-230	722.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_9627323_3	1267211.KI669560_gene2044	2.955e-94	317.0	COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,1IS7G@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 domain	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
HKD3_k127_9627323_0	1267211.KI669560_gene577	3.583e-266	822.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
HKD3_k127_9640034_0	696747.NIES39_C05180	4.089e-71	262.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
HKD3_k127_9640034_3	1227739.Hsw_0287	1.014e-16	94.0	COG2374@1|root,COG5184@1|root,COG2374@2|Bacteria,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,47T9H@768503|Cytophagia	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
HKD3_k127_9640034_1	237609.PSAKL28_28400	3.364e-45	168.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
HKD3_k127_9640034_2	631362.Thi970DRAFT_04157	7.253e-17	93.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WVXQ@135613|Chromatiales	135613|Chromatiales	O	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_2,TPR_8
HKD3_k127_9640034_4	1121957.ATVL01000010_gene223	2.799e-09	60.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,47KIP@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
## 2837 queries scanned
## Total time (seconds): 164.24146938323975
## Rate: 17.27 q/s