## Sat Nov 16 06:37:19 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin9/HKD_3_bin.49.fa -m mmseqs --itype genome -o HKD_3_bin.49 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HKD_3_bin.49 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD3_k127_1001795_1	985255.APHJ01000037_gene2876	6.984e-70	243.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,1I0S1@117743|Flavobacteriia,2P7C6@244698|Gillisia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_1001795_0	946077.W5A_04384	2.904e-106	362.0	COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,1HYAV@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
HKD3_k127_1001795_2	1296415.JACC01000021_gene4214	2.614e-33	146.0	COG2755@1|root,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,1I0ZE@117743|Flavobacteriia,2YGKA@290174|Aquimarina	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
HKD3_k127_1217656_1	1121104.AQXH01000001_gene1966	2.228e-129	426.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1IP8M@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_1217656_2	760192.Halhy_4853	1.678e-90	308.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1IQ05@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
HKD3_k127_1217656_0	1122176.KB903554_gene3989	0.0	1045.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD3_k127_1217656_3	1313421.JHBV01000029_gene2012	1.079e-70	249.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,1IWXG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_1226488_2	1237149.C900_01165	1.154e-25	107.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,47K6T@768503|Cytophagia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
HKD3_k127_1226488_1	1122176.KB903547_gene1108	2.336e-48	187.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_1226488_0	760192.Halhy_4157	2.989e-57	207.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,1IYDB@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_1234874_4	1122176.KB903531_gene2974	7.34e-93	316.0	COG0366@1|root,COG0366@2|Bacteria,4PKH4@976|Bacteroidetes	976|Bacteroidetes	G	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
HKD3_k127_1234874_1	1122176.KB903531_gene2973	4.179e-285	893.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1IREB@117747|Sphingobacteriia	976|Bacteroidetes	M	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_1234874_0	1122176.KB903531_gene2972	0.0	1022.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1INQB@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1234874_2	1250278.JQNQ01000001_gene3177	2.29e-231	744.0	COG3934@1|root,COG3934@2|Bacteria,4NFVS@976|Bacteroidetes,1HZVW@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
HKD3_k127_1234874_3	925409.KI911562_gene1788	3.071e-123	402.0	COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,1IWTZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HKD3_k127_1240415_1	1122179.KB890413_gene4675	2.918e-124	402.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HKD3_k127_1240415_2	926551.KB900705_gene506	1.657e-43	161.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia,1ERYG@1016|Capnocytophaga	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HKD3_k127_1240415_0	760192.Halhy_3598	1.48e-249	780.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NEXG@976|Bacteroidetes,1IPN6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
HKD3_k127_1253434_1	760192.Halhy_1118	1.261e-205	665.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1J0WH@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1253434_0	1502850.FG91_03983	1.647e-271	855.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2TS28@28211|Alphaproteobacteria,2JZVY@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_1253434_2	1122179.KB890419_gene54	1.717e-190	604.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
HKD3_k127_1253434_3	760192.Halhy_1117	2.231e-88	309.0	COG3291@1|root,COG3291@2|Bacteria,4NI6I@976|Bacteroidetes	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1262002_0	1122179.KB890434_gene853	1.451e-87	304.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1IP5H@117747|Sphingobacteriia	976|Bacteroidetes	NU	COG1705 Muramidase (flagellum-specific)	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
HKD3_k127_1262002_1	760192.Halhy_3019	8.562e-66	239.0	COG0457@1|root,COG0457@2|Bacteria,4NJWY@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
HKD3_k127_1267071_5	1408473.JHXO01000001_gene2101	2.368e-52	203.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,2FN4U@200643|Bacteroidia	976|Bacteroidetes	D	Peptidase, M23 family	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_1267071_8	760192.Halhy_3010	1.756e-18	95.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1ITXE@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
HKD3_k127_1267071_4	1122176.KB903555_gene3735	3.293e-63	239.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IR0N@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HKD3_k127_1267071_0	1122176.KB903548_gene1151	2.943e-197	625.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HKD3_k127_1267071_7	485918.Cpin_0363	5.019e-32	126.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1ITA3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD3_k127_1267071_1	760192.Halhy_2560	2.688e-178	567.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HKD3_k127_1267071_2	1122176.KB903548_gene1148	3.85e-95	317.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HKD3_k127_1267071_6	1288963.ADIS_1763	1.91e-46	170.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,47R7B@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
HKD3_k127_1267071_3	984262.SGRA_3362	1.545e-93	315.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_1269013_1	886379.AEWI01000091_gene1606	2.428e-121	405.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07636,ko:K07645	ko02020,ko02024,map02020,map02024	M00434,M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HKD3_k127_1269013_2	886379.AEWI01000091_gene1605	1.036e-66	237.0	COG1592@1|root,COG1592@2|Bacteria,4NKH9@976|Bacteroidetes,2FTZC@200643|Bacteroidia	976|Bacteroidetes	C	Rubredoxin	rubY	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HKD3_k127_1269013_0	1380393.JHVP01000003_gene1268	1.939e-161	520.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
HKD3_k127_1269013_5	1453498.LG45_14960	0.0001597	52.0	COG3291@1|root,COG3291@2|Bacteria,4NFRR@976|Bacteroidetes,1I0VP@117743|Flavobacteriia,2NTV3@237|Flavobacterium	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
HKD3_k127_1269013_4	1356852.N008_17600	6.18e-29	127.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
HKD3_k127_1269013_3	1239962.C943_02138	2.154e-32	128.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes,47UWC@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
HKD3_k127_128115_3	504472.Slin_5068	5.874e-52	190.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,47JWZ@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
HKD3_k127_128115_2	761193.Runsl_5061	7.517e-65	229.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,47JWZ@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
HKD3_k127_128115_1	1313421.JHBV01000008_gene4392	2.597e-84	306.0	COG0457@1|root,COG0457@2|Bacteria,4P298@976|Bacteroidetes,1J19F@117747|Sphingobacteriia	976|Bacteroidetes	S	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
HKD3_k127_128115_0	929556.Solca_1867	3.071e-168	541.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_128115_4	760192.Halhy_0204	3.664e-47	185.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,1INMI@117747|Sphingobacteriia	976|Bacteroidetes	S	alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
HKD3_k127_1283144_0	929713.NIASO_14750	3.78e-135	436.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD3_k127_1283144_2	1121875.KB907548_gene1381	8.284e-71	254.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_1283144_1	760192.Halhy_3086	5.723e-99	332.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1IVKB@117747|Sphingobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
HKD3_k127_1285089_2	760192.Halhy_1829	1.524e-32	132.0	COG0457@1|root,COG0457@2|Bacteria,4NNMV@976|Bacteroidetes	976|Bacteroidetes	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1285089_1	485918.Cpin_0869	3.683e-148	485.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_1285089_0	760192.Halhy_2931	1.434e-153	490.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,1IR2B@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
HKD3_k127_1285089_3	1160137.KB907307_gene1438	2.544e-11	70.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria,4G5TG@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
HKD3_k127_1306603_1	1122179.KB890422_gene2220	1.223e-52	190.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1IRQM@117747|Sphingobacteriia	976|Bacteroidetes	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HKD3_k127_1306603_0	1313301.AUGC01000003_gene2156	2.349e-54	200.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HKD3_k127_1306603_2	760192.Halhy_0135	1.79e-22	100.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IQAC@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
HKD3_k127_1339181_1	1122176.KB903532_gene2597	1.118e-40	173.0	COG4206@1|root,COG4206@2|Bacteria,4PM79@976|Bacteroidetes,1J0WJ@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
HKD3_k127_1339181_0	1122176.KB903532_gene2598	9.523e-55	204.0	COG3712@1|root,COG3712@2|Bacteria,4NNSK@976|Bacteroidetes,1ISMZ@117747|Sphingobacteriia	976|Bacteroidetes	PT	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_1339181_2	1121904.ARBP01000001_gene5638	2.785e-23	100.0	2AB14@1|root,339IP@2|Bacteria,4NZD5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1357522_3	1236494.BAJN01000002_gene359	7.302e-100	333.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD3_k127_1357522_7	760192.Halhy_1161	1.138e-42	162.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IY8G@117747|Sphingobacteriia	976|Bacteroidetes	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HKD3_k127_1357522_4	700598.Niako_4421	3.59e-98	326.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD3_k127_1357522_0	760192.Halhy_6488	2.15e-305	955.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_1357522_9	755732.Fluta_2763	2.31e-24	103.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia	976|Bacteroidetes	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD3_k127_1357522_5	760192.Halhy_4645	5.653e-65	237.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes,1ITRX@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1357522_8	1191523.MROS_1144	1.525e-36	143.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD3_k127_1357522_2	1120965.AUBV01000014_gene1158	6.307e-127	419.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,47N0I@768503|Cytophagia	976|Bacteroidetes	M	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
HKD3_k127_1357522_1	1237149.C900_03053	3.522e-167	536.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,47NZ3@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HKD3_k127_1357522_6	388413.ALPR1_08988	2.709e-43	167.0	2ATWF@1|root,31JFP@2|Bacteria,4NQPB@976|Bacteroidetes,47SD4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1357522_11	1121904.ARBP01000005_gene4494	2.759e-06	55.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1357544_3	1198452.Jab_1c18950	7.113e-25	121.0	COG0642@1|root,COG2203@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG3292@2|Bacteria,1RGKE@1224|Proteobacteria,2WHKS@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,Response_reg
HKD3_k127_1357544_1	1121288.AULL01000016_gene879	4.348e-68	238.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia,3ZPP3@59732|Chryseobacterium	976|Bacteroidetes	D	ABC transporter, ATP-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD3_k127_1357544_2	1122176.KB903609_gene5249	8.802e-33	133.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
HKD3_k127_1357544_0	1122176.KB903609_gene5250	9.143e-261	829.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IQAC@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
HKD3_k127_1374169_0	760192.Halhy_1865	2.232e-235	762.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD3_k127_1374169_1	1227739.Hsw_0103	7.978e-49	183.0	COG0463@1|root,COG0463@2|Bacteria,4PP1X@976|Bacteroidetes,47RH9@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_1374169_3	760192.Halhy_5429	1.925e-34	134.0	2C4KB@1|root,32YM4@2|Bacteria,4NUZU@976|Bacteroidetes,1IU8Z@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1374169_2	1279009.ADICEAN_03715	1.38e-45	169.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,47QTE@768503|Cytophagia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD3_k127_1378296_6	600809.BPLAN_139	5.766e-13	71.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1HWW7@117743|Flavobacteriia,3IV4S@39782|Blattabacteriaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_1378296_3	1499967.BAYZ01000061_gene5977	1.954e-127	445.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,PAS_9,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_1378296_8	1121898.Q766_19390	3.081e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,4NQVU@976|Bacteroidetes,1I7N2@117743|Flavobacteriia,2NUWG@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12,TPR_7,TPR_8
HKD3_k127_1378296_7	1121101.HMPREF1532_01478	1.038e-08	68.0	COG3291@1|root,COG3291@2|Bacteria,4NKVV@976|Bacteroidetes,2FM9I@200643|Bacteroidia,4AT4Z@815|Bacteroidaceae	976|Bacteroidetes	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HKD3_k127_1378296_4	1288963.ADIS_1931	1.254e-34	151.0	COG3291@1|root,COG3291@2|Bacteria,4NJAF@976|Bacteroidetes,47P0M@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HKD3_k127_1378296_0	471854.Dfer_5599	2.812e-304	963.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_1378296_2	471854.Dfer_5600	6.09e-160	517.0	COG0702@1|root,COG0702@2|Bacteria,4NHAI@976|Bacteroidetes,47Y9C@768503|Cytophagia	976|Bacteroidetes	GM	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_1378296_1	1267211.KI669560_gene1251	5.295e-183	586.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1IPDB@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD3_k127_1378296_5	1086011.HJ01_01011	4.641e-26	111.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZ6@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD3_k127_1380193_6	1122176.KB903619_gene5382	4.279e-25	113.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HKD3_k127_1380193_7	649349.Lbys_2495	4.942e-16	85.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,47MRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_1380193_5	760192.Halhy_0949	1.369e-25	118.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,1ITA7@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_1380193_2	1122176.KB903619_gene5417	6.034e-107	366.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_1380193_0	1122176.KB903531_gene3022	1.577e-255	811.0	COG1629@1|root,COG1629@2|Bacteria,4NKDS@976|Bacteroidetes,1IXCR@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
HKD3_k127_1380193_3	760192.Halhy_4644	1.323e-89	305.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD3_k127_1380193_1	1121012.AUKX01000001_gene1258	9.781e-111	373.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1HXSW@117743|Flavobacteriia,23GCB@178469|Arenibacter	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_1380193_4	1121859.KB890738_gene3354	2.25e-70	246.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47MZ0@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
HKD3_k127_1390487_1	1122176.KB903535_gene2035	3.948e-119	400.0	COG4206@1|root,COG4206@2|Bacteria,4PKF2@976|Bacteroidetes,1J0GX@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1390487_3	760192.Halhy_2751	4.713e-85	293.0	arCOG12964@1|root,2Z7HP@2|Bacteria,4P10P@976|Bacteroidetes	976|Bacteroidetes	S	Tocopherol cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Tocopherol_cycl
HKD3_k127_1390487_5	925409.KI911562_gene1150	1.018e-07	64.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,1IUMD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
HKD3_k127_1390487_2	760192.Halhy_3583	5.805e-103	340.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1IPP4@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD3_k127_1390487_4	1122176.KB903548_gene1155	1.187e-52	193.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1IT9X@117747|Sphingobacteriia	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_1390487_0	984262.SGRA_1904	0.0	1046.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD3_k127_1394169_20	1250232.JQNJ01000001_gene1753	3.87e-20	108.0	COG1361@1|root,COG2373@1|root,COG2911@1|root,COG3209@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11
HKD3_k127_1394169_19	760192.Halhy_1203	1.693e-31	145.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD3_k127_1394169_11	1235457.C404_09985	1.183e-77	266.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,1JZY9@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_1394169_17	1227488.C477_10213	5.151e-39	150.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HKD3_k127_1394169_21	1122176.KB903531_gene3117	1.518e-19	99.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1IR8U@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1394169_2	1122176.KB903531_gene3118	1.796e-169	538.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD3_k127_1394169_12	1122179.KB890434_gene889	5.49e-71	246.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1IPI8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
HKD3_k127_1394169_16	760192.Halhy_6292	6.633e-46	173.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1ITRK@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_1394169_13	385682.AFSL01000003_gene1885	3.072e-59	214.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,2FM94@200643|Bacteroidia,3XIV7@558415|Marinilabiliaceae	976|Bacteroidetes	S	Alanine racemase, N-terminal domain	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD3_k127_1394169_5	1122176.KB903531_gene3008	5.697e-100	331.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1INU0@117747|Sphingobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD3_k127_1394169_4	391598.FBBAL38_01410	2.106e-103	343.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_1394169_14	1122605.KB893629_gene4122	2.564e-58	213.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1IRY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HKD3_k127_1394169_18	1121104.AQXH01000001_gene1846	5.642e-37	146.0	2CBKC@1|root,32RTJ@2|Bacteria,4NTE7@976|Bacteroidetes,1ITRI@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1394169_1	760192.Halhy_6493	4.153e-215	685.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IX27@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_1394169_10	1144313.PMI10_03070	1.114e-81	278.0	COG2067@1|root,COG2067@2|Bacteria,4NGWZ@976|Bacteroidetes,1IJ7F@117743|Flavobacteriia,2NUCT@237|Flavobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_1394169_0	760192.Halhy_2077	0.0	1226.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVNR@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_1394169_8	1094466.KQS_02405	9.166e-94	336.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia,2NVE3@237|Flavobacterium	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
HKD3_k127_1394169_22	1122179.KB890427_gene3865	2.334e-19	104.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
HKD3_k127_1394169_23	431947.PGN_0561	4.963e-07	58.0	2DKMJ@1|root,309XW@2|Bacteria,4NNRT@976|Bacteroidetes,2FQNM@200643|Bacteroidia,2322J@171551|Porphyromonadaceae	976|Bacteroidetes	M	Spi protease inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I69,Peptidase_C10
HKD3_k127_1394169_9	1122176.KB903598_gene4613	3.207e-91	306.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HKD3_k127_1394169_3	1121904.ARBP01000006_gene3982	7.023e-108	368.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HKD3_k127_1394169_15	760192.Halhy_2639	5.143e-51	194.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_1394169_7	1313421.JHBV01000005_gene4509	1.231e-95	344.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPTT@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
HKD3_k127_1394169_6	1122176.KB903547_gene1111	4.708e-99	337.0	COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_1410140_10	760192.Halhy_0347	4.57e-50	181.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD3_k127_1410140_12	760192.Halhy_0348	9.747e-40	158.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IQ1U@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
HKD3_k127_1410140_6	1122179.KB890438_gene1563	2.162e-102	343.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD3_k127_1410140_7	760192.Halhy_0350	1.382e-64	231.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HKD3_k127_1410140_16	1122176.KB903609_gene5235	3.953e-27	122.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,1ITPJ@117747|Sphingobacteriia	976|Bacteroidetes	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
HKD3_k127_1410140_1	1122176.KB903609_gene5236	2.254e-169	549.0	COG0699@1|root,COG0699@2|Bacteria,4NTQB@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
HKD3_k127_1410140_15	1168034.FH5T_16470	1.177e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,4NS8T@976|Bacteroidetes,2FRUY@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_1410140_11	1313421.JHBV01000036_gene2442	7.724e-41	156.0	28P9K@1|root,2ZC31@2|Bacteria,4NPW6@976|Bacteroidetes,1IYXR@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
HKD3_k127_1410140_2	1122176.KB903545_gene853	2.792e-160	507.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_1410140_14	760192.Halhy_4723	5.9e-35	138.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1ISF1@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD3_k127_1410140_3	153721.MYP_2591	4.018e-150	482.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,47KZW@768503|Cytophagia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_1410140_17	1124780.ANNU01000017_gene1940	5.808e-23	111.0	COG3712@1|root,COG3712@2|Bacteria,4NKN5@976|Bacteroidetes,47NYQ@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4880,DUF4974,FecR
HKD3_k127_1410140_13	1122176.KB903531_gene3143	5.426e-37	146.0	COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,1IS89@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_1410140_9	1122176.KB903538_gene1523	2.153e-60	219.0	COG0508@1|root,COG0508@2|Bacteria,4NJ7Y@976|Bacteroidetes,1IS8F@117747|Sphingobacteriia	976|Bacteroidetes	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1410140_4	714943.Mucpa_1462	4.311e-131	431.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
HKD3_k127_1410140_0	865937.Gilli_0452	7.419e-189	606.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1I0MT@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_1410140_8	1122176.KB903541_gene285	1.223e-60	219.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1ISXT@117747|Sphingobacteriia	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_1410140_5	1122176.KB903546_gene1028	3.388e-121	412.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Cytochrome_C554,Glyco_hydro_26,PA14,RsgI_N
HKD3_k127_1431402_1	1121481.AUAS01000004_gene1657	6.967e-66	253.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug
HKD3_k127_1431402_0	1313421.JHBV01000041_gene3707	2.62e-128	434.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
HKD3_k127_1441047_1	1313421.JHBV01000003_gene588	1.41e-185	595.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1IQIE@117747|Sphingobacteriia	976|Bacteroidetes	S	FAD-dependent dehydrogenase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
HKD3_k127_1441047_6	760192.Halhy_4531	6.449e-38	154.0	COG2259@1|root,COG2259@2|Bacteria,4NYPC@976|Bacteroidetes,1IZT9@117747|Sphingobacteriia	976|Bacteroidetes	S	SURF4 family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX,SURF4
HKD3_k127_1441047_9	1219072.VHA01S_024_00630	1.619e-08	61.0	COG1396@1|root,COG1396@2|Bacteria,1RHIT@1224|Proteobacteria,1S64Z@1236|Gammaproteobacteria,1Y37Q@135623|Vibrionales	135623|Vibrionales	K	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM,HTH_3
HKD3_k127_1441047_2	1122176.KB903534_gene2215	8.632e-160	531.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1IPU7@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HKD3_k127_1441047_4	243924.LT42_16490	3.499e-68	245.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0246 family	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
HKD3_k127_1441047_7	926562.Oweho_1037	3.941e-33	133.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_1441047_8	1392488.JHZY01000002_gene1185	7.685e-18	93.0	COG3427@1|root,COG3427@2|Bacteria,4NQ8R@976|Bacteroidetes,1I3CY@117743|Flavobacteriia	976|Bacteroidetes	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HKD3_k127_1441047_3	1122179.KB890441_gene1065	6.075e-143	478.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD3_k127_1441047_0	313596.RB2501_04115	1.903e-274	859.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
HKD3_k127_1441047_5	1158294.JOMI01000007_gene162	6.167e-56	208.0	COG0451@1|root,COG0451@2|Bacteria,4NEJJ@976|Bacteroidetes,2FNM5@200643|Bacteroidia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
HKD3_k127_1443000_1	471854.Dfer_4407	2.852e-165	525.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_1443000_2	1406840.Q763_04040	1.044e-123	405.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia,2NT4H@237|Flavobacterium	976|Bacteroidetes	GM	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD3_k127_1443000_0	1122179.KB890413_gene4767	1.75e-210	676.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD3_k127_1443000_3	1313301.AUGC01000003_gene1927	3.865e-05	49.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HKD3_k127_1452180_4	760192.Halhy_1117	1.234e-71	256.0	COG3291@1|root,COG3291@2|Bacteria,4NI6I@976|Bacteroidetes	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1452180_0	760192.Halhy_1116	5.686e-176	573.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IPV2@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2329)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3131,Glycoamylase
HKD3_k127_1452180_2	984262.SGRA_1614	1.359e-80	273.0	COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,1IXQF@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_1452180_3	1122179.KB890425_gene3352	1.365e-78	272.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1ISBF@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HKD3_k127_1452180_1	1122176.KB903543_gene622	3.036e-147	473.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_1452180_5	1122179.KB890419_gene33	3.411e-60	215.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,1IR96@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Pseudouridine synthase, RsuA and RluB C D E F	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD3_k127_1452180_7	1123326.JFBL01000010_gene735	4.118e-32	134.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2YPK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HKD3_k127_1452180_6	760192.Halhy_2598	4.38e-37	144.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
HKD3_k127_1453469_8	1121904.ARBP01000022_gene3489	2.109e-51	199.0	COG2931@1|root,COG4733@1|root,COG5306@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,COG5306@2|Bacteria,4NR3S@976|Bacteroidetes,47RKF@768503|Cytophagia	976|Bacteroidetes	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
HKD3_k127_1453469_5	1121957.ATVL01000008_gene4646	2.926e-90	332.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_1453469_7	760192.Halhy_2543	2.599e-62	225.0	COG2197@1|root,COG2197@2|Bacteria,4NF5P@976|Bacteroidetes,1IT9D@117747|Sphingobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_1453469_1	929556.Solca_3029	5.117e-248	839.0	COG1361@1|root,COG4733@1|root,COG1361@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PKD,SLH,fn3
HKD3_k127_1453469_13	153721.MYP_2713	3.777e-07	65.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD3_k127_1453469_3	1120965.AUBV01000008_gene1963	1.445e-154	494.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HKD3_k127_1453469_2	760192.Halhy_6043	1.11e-184	601.0	COG0514@1|root,COG0514@2|Bacteria,4NG10@976|Bacteroidetes,1IQU0@117747|Sphingobacteriia	976|Bacteroidetes	L	RQC	recQ3	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HKD3_k127_1453469_6	760192.Halhy_2920	5.024e-69	251.0	COG1331@1|root,COG1331@2|Bacteria,4NMU8@976|Bacteroidetes,1IYIZ@117747|Sphingobacteriia	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
HKD3_k127_1453469_0	1122176.KB903540_gene101	0.0	1134.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1IQ9E@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
HKD3_k127_1453469_11	1122179.KB890491_gene4460	1.319e-07	61.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
HKD3_k127_1453469_12	906888.JCM19314_2307	3.558e-07	60.0	COG5343@1|root,COG5343@2|Bacteria,4NH0S@976|Bacteroidetes,1HY07@117743|Flavobacteriia,3HKKT@363408|Nonlabens	976|Bacteroidetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
HKD3_k127_1453469_10	1408433.JHXV01000008_gene84	2.986e-14	83.0	COG0810@1|root,COG2849@1|root,COG0810@2|Bacteria,COG2849@2|Bacteria,4NW2U@976|Bacteroidetes,1IIR8@117743|Flavobacteriia	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
HKD3_k127_1453469_9	1304872.JAGC01000003_gene3784	2.907e-36	145.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,42U9T@68525|delta/epsilon subdivisions,2WQPQ@28221|Deltaproteobacteria,2MCJT@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
HKD3_k127_1453469_4	1122176.KB903532_gene2605	1.21e-128	422.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1IRGW@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
HKD3_k127_1488295_3	760192.Halhy_4481	1.319e-56	221.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CBM_3,CHU_C,SprB
HKD3_k127_1488295_4	1346330.M472_16550	1.01e-52	193.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,1IR72@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HKD3_k127_1488295_0	760192.Halhy_2198	2.568e-286	914.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1IRKN@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HKD3_k127_1488295_1	1313421.JHBV01000030_gene2310	1.651e-103	346.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG3752 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
HKD3_k127_1488295_2	1189612.A33Q_2629	1.771e-67	236.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD3_k127_1488295_6	1185876.BN8_01920	1.732e-26	113.0	COG1670@1|root,COG1670@2|Bacteria,4NTU9@976|Bacteroidetes,47UWA@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
HKD3_k127_1488295_7	1242864.D187_002155	1.027e-16	94.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
HKD3_k127_1488295_5	1123057.P872_02000	7.693e-48	181.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
HKD3_k127_1502432_3	760192.Halhy_0093	6.826e-38	147.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1ITFC@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
HKD3_k127_1502432_0	1122179.KB890433_gene4036	2.213e-107	359.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1IQ3E@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_1502432_1	1122176.KB903609_gene5147	3.007e-98	338.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1IRH5@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_1502432_2	471854.Dfer_0223	6.151e-77	268.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,47MUJ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD3_k127_1502432_4	1392488.JHZY01000002_gene203	7.284e-30	139.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia,2XHZJ@283735|Leeuwenhoekiella	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
HKD3_k127_1539820_6	319236.JCM19294_1494	4.275e-09	66.0	COG3637@1|root,COG3637@2|Bacteria,4NM4E@976|Bacteroidetes,1I1FR@117743|Flavobacteriia,3HKAD@363408|Nonlabens	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_1539820_3	1122176.KB903542_gene334	5.976e-99	330.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD3_k127_1539820_0	760192.Halhy_3123	3.282e-307	964.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HKD3_k127_1539820_4	1122176.KB903550_gene4299	2.274e-98	334.0	COG2267@1|root,COG2267@2|Bacteria,4NK38@976|Bacteroidetes,1IT00@117747|Sphingobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
HKD3_k127_1539820_2	760192.Halhy_3279	4.676e-112	375.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1J0MH@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HKD3_k127_1539820_1	984262.SGRA_0552	9.403e-226	712.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HKD3_k127_1539820_5	1346330.M472_21270	7.885e-51	188.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1J0J7@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
HKD3_k127_1611001_5	1086011.HJ01_03312	1.495e-31	126.0	COG0500@1|root,COG0500@2|Bacteria,4PM8S@976|Bacteroidetes,1IJMZ@117743|Flavobacteriia,2P0RG@237|Flavobacterium	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31,NodS
HKD3_k127_1611001_2	760192.Halhy_0356	4.513e-244	766.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1INQD@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD3_k127_1611001_1	865938.Weevi_0055	3.148e-265	835.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
HKD3_k127_1611001_3	865938.Weevi_0058	1.144e-121	403.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
HKD3_k127_1611001_0	1121285.AUFK01000017_gene3100	0.0	1808.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia,3ZQFF@59732|Chryseobacterium	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
HKD3_k127_1611001_4	1336803.PHEL49_2566	2.902e-35	152.0	COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,Gly_rich,HYR,Laminin_G_3,PKD,SprB,TSP_3
HKD3_k127_1622646_2	925409.KI911562_gene669	6.69e-186	608.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_1622646_5	1122176.KB903536_gene1782	5.107e-99	333.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HKD3_k127_1622646_6	1122176.KB903536_gene1786	1.075e-97	333.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1INRI@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
HKD3_k127_1622646_1	760192.Halhy_2311	1.481e-192	635.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IP00@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_1622646_14	879243.Poras_0241	1.012e-13	87.0	COG0526@1|root,COG0526@2|Bacteria,4P5ZH@976|Bacteroidetes	976|Bacteroidetes	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1622646_8	1279009.ADICEAN_01177	9.111e-91	340.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
HKD3_k127_1622646_0	1122176.KB903536_gene1794	2.229e-221	726.0	COG1361@1|root,COG2356@1|root,COG3291@1|root,COG1361@2|Bacteria,COG2356@2|Bacteria,COG3291@2|Bacteria,4PM78@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
HKD3_k127_1622646_17	1121481.AUAS01000001_gene4361	4.26e-09	67.0	COG3637@1|root,COG3637@2|Bacteria,4NVY6@976|Bacteroidetes,47S8N@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_1622646_9	1279009.ADICEAN_01273	1.292e-58	215.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,47P6H@768503|Cytophagia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD3_k127_1622646_3	760192.Halhy_6085	8.102e-154	507.0	COG2937@1|root,COG2937@2|Bacteria,4NK5H@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_1622646_10	760192.Halhy_6084	5.024e-43	164.0	COG5018@1|root,COG5018@2|Bacteria	2|Bacteria	L	Exonuclease	exoN1	-	-	-	-	-	-	-	-	-	-	-	RNase_T
HKD3_k127_1622646_7	1166018.FAES_1173	2.318e-95	323.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD3_k127_1622646_4	1411685.U062_01937	8.585e-122	400.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,1J7N5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574	AIRS,AIRS_C
HKD3_k127_1622646_11	207954.MED92_10869	7.624e-29	127.0	COG3204@1|root,COG3204@2|Bacteria,1RG81@1224|Proteobacteria,1RY2C@1236|Gammaproteobacteria,1XP5C@135619|Oceanospirillales	135619|Oceanospirillales	L	pilus organization	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1622646_15	1166018.FAES_4114	6.1e-12	68.0	28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,47KRG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
HKD3_k127_1643165_3	99598.Cal7507_5814	1.477e-81	277.0	COG4221@1|root,COG4221@2|Bacteria,1G2X4@1117|Cyanobacteria,1HRY9@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_1643165_2	1121889.AUDM01000002_gene337	5.066e-86	313.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia,2NVE3@237|Flavobacterium	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_1643165_4	1353276.JADR01000006_gene1080	2.088e-17	97.0	COG5295@1|root,COG5295@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1643165_0	1121889.AUDM01000002_gene337	1.473e-113	400.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia,2NVE3@237|Flavobacterium	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_1643165_1	700598.Niako_4749	1.044e-90	320.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_1643480_1	760192.Halhy_4134	3.774e-128	419.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1IP9F@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
HKD3_k127_1643480_0	1408473.JHXO01000007_gene998	2.679e-168	546.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HKD3_k127_1643480_2	880073.Calab_2100	2.022e-22	102.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
HKD3_k127_1735739_2	468059.AUHA01000006_gene2872	1.004e-08	57.0	COG2931@1|root,COG2931@2|Bacteria,4PN0W@976|Bacteroidetes	976|Bacteroidetes	Q	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
HKD3_k127_1735739_1	1121889.AUDM01000002_gene448	1.4e-12	81.0	COG3210@1|root,COG4675@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_1735739_0	1267534.KB906757_gene1087	2.065e-46	182.0	COG0457@1|root,COG0457@2|Bacteria,3Y75Q@57723|Acidobacteria,2JM57@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_179762_4	1239962.C943_04539	1.888e-13	71.0	COG1136@1|root,COG1136@2|Bacteria,4NE65@976|Bacteroidetes,47KXA@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_179762_2	194439.CT1335	1.939e-28	119.0	COG4704@1|root,COG4704@2|Bacteria,1FFAT@1090|Chlorobi	1090|Chlorobi	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
HKD3_k127_179762_1	1239962.C943_04540	2.807e-73	260.0	COG1566@1|root,COG1566@2|Bacteria,4NMQ2@976|Bacteroidetes,47PKJ@768503|Cytophagia	976|Bacteroidetes	V	HlyD family secretion protein	ydhJ	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD3_k127_179762_0	1239962.C943_04541	8.737e-166	528.0	COG0577@1|root,COG0577@2|Bacteria,4NEIP@976|Bacteroidetes,47KH8@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD3_k127_179762_3	1239962.C943_04542	1.472e-20	93.0	COG1538@1|root,COG1538@2|Bacteria,4NX70@976|Bacteroidetes	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_1965229_0	760192.Halhy_2216	8.735e-99	349.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_207982_2	1305737.JAFX01000001_gene3299	1.646e-07	54.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,47JJY@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_207982_0	1122176.KB903532_gene2669	1.218e-148	490.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
HKD3_k127_207982_1	1122176.KB903536_gene1870	3.917e-84	290.0	COG3118@1|root,COG3118@2|Bacteria,4PMAJ@976|Bacteroidetes	976|Bacteroidetes	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
HKD3_k127_2086604_2	760192.Halhy_3485	9.852e-140	453.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1IT0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
HKD3_k127_2086604_5	391587.KAOT1_15948	4.346e-34	136.0	29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes,1I2ET@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
HKD3_k127_2086604_6	981384.AEYW01000022_gene3495	2.423e-27	118.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2TSWJ@28211|Alphaproteobacteria,4ND3B@97050|Ruegeria	28211|Alphaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HKD3_k127_2086604_1	1122176.KB903548_gene1197	1.77e-167	531.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1INQ9@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD3_k127_2086604_4	984262.SGRA_2881	1.869e-54	199.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1IS0X@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
HKD3_k127_2086604_0	760192.Halhy_3588	0.0	1067.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_2086604_3	1122176.KB903546_gene992	1.16e-130	430.0	COG0577@1|root,COG0577@2|Bacteria,4NF60@976|Bacteroidetes,1J0VQ@117747|Sphingobacteriia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_2158327_1	1122176.KB903535_gene2035	6.939e-83	288.0	COG4206@1|root,COG4206@2|Bacteria,4PKF2@976|Bacteroidetes,1J0GX@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_2158327_3	216432.CA2559_08646	3.35e-47	180.0	29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,1I2DS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2158327_2	1521187.JPIM01000017_gene337	5.509e-74	254.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
HKD3_k127_2158327_0	991.IW20_14005	3.119e-162	532.0	COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia,2NVCS@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
HKD3_k127_2261512_0	1122176.KB903536_gene1870	4.003e-81	278.0	COG3118@1|root,COG3118@2|Bacteria,4PMAJ@976|Bacteroidetes	976|Bacteroidetes	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
HKD3_k127_2261512_2	1122176.KB903532_gene2672	5.449e-69	246.0	2AM3F@1|root,31BXJ@2|Bacteria,4NPAN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2261512_1	1122176.KB903532_gene2673	5.247e-73	252.0	COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,1IW8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
HKD3_k127_2270712_2	926562.Oweho_3340	4.471e-11	68.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Sulfatase
HKD3_k127_2313197_4	1288963.ADIS_1688	4.303e-37	140.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47K0E@768503|Cytophagia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD3_k127_2313197_0	760192.Halhy_3177	2.438e-139	458.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1IQGD@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
HKD3_k127_2313197_2	468059.AUHA01000002_gene864	7.339e-59	218.0	COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1J0IW@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
HKD3_k127_2313197_3	760192.Halhy_3175	5.504e-52	188.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1ISUU@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutathione peroxidase	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD3_k127_2313197_1	1122176.KB903539_gene1393	7.12e-88	296.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1IVF8@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
HKD3_k127_2313197_5	1122179.KB890415_gene2035	1.045e-20	98.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
HKD3_k127_2433072_2	760192.Halhy_2716	9.073e-53	194.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1INQY@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD3_k127_2433072_1	760192.Halhy_3530	1.383e-68	238.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,1IPYA@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_2433072_0	1501391.LG35_00135	9.408e-87	298.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,2FNMQ@200643|Bacteroidia,22V04@171550|Rikenellaceae	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
HKD3_k127_2433072_3	992406.RIA_1868	2.857e-34	133.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome c biogenesis	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
HKD3_k127_2448570_1	1313421.JHBV01000021_gene4837	2.297e-101	338.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1IQ9R@117747|Sphingobacteriia	976|Bacteroidetes	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD3_k127_2448570_2	314266.SKA58_18077	1.815e-26	117.0	COG3963@1|root,COG3963@2|Bacteria,1R81B@1224|Proteobacteria,2U46R@28211|Alphaproteobacteria,2K2HK@204457|Sphingomonadales	204457|Sphingomonadales	I	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD3_k127_2448570_3	762903.Pedsa_3675	2.262e-13	76.0	2BXI1@1|root,32R1C@2|Bacteria,4NR9I@976|Bacteroidetes,1ISYI@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2448570_0	886377.Murru_2265	3.82e-144	471.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1HX1G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD3_k127_246738_1	1122176.KB903554_gene3838	2.045e-258	805.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IQEH@117747|Sphingobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
HKD3_k127_246738_5	1122179.KB890497_gene2856	1.17e-69	239.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1ISUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD3_k127_246738_8	1178825.ALIH01000001_gene2633	1.151e-37	151.0	COG5522@1|root,COG5522@2|Bacteria,4NG1T@976|Bacteroidetes,1HYI4@117743|Flavobacteriia	976|Bacteroidetes	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
HKD3_k127_246738_2	1122176.KB903554_gene3923	7.342e-251	795.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,1IX0B@117747|Sphingobacteriia	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
HKD3_k127_246738_3	1392490.JHZX01000001_gene2799	3.134e-165	534.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1HX25@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
HKD3_k127_246738_7	1353276.JADR01000002_gene2016	3.724e-38	167.0	COG1520@1|root,COG1520@2|Bacteria,4NEVC@976|Bacteroidetes,1IJFE@117743|Flavobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_246738_6	1313421.JHBV01000038_gene2841	1.594e-60	240.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF1983,DUF3672,Glyco_hydro_28,HYR,PA14,Pectate_lyase_3
HKD3_k127_246738_9	1185876.BN8_00772	8.803e-13	83.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB,TIG
HKD3_k127_246738_4	1267211.KI669560_gene1734	2.665e-83	284.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1IPGF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HKD3_k127_246738_0	1122176.KB903531_gene2778	6.187e-279	874.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD3_k127_2468521_7	926562.Oweho_0356	3.15e-11	68.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HWJR@117743|Flavobacteriia,2PBB9@246874|Cryomorphaceae	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43
HKD3_k127_2468521_1	1122176.KB903545_gene901	4.048e-110	364.0	COG0451@1|root,COG0451@2|Bacteria,4NGE6@976|Bacteroidetes	976|Bacteroidetes	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
HKD3_k127_2468521_2	1122176.KB903560_gene3549	6.357e-104	345.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1IPR7@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
HKD3_k127_2468521_9	313598.MED152_08220	0.0002417	53.0	28IHD@1|root,2Z8IK@2|Bacteria,4NF9V@976|Bacteroidetes,1HY20@117743|Flavobacteriia,3VV3N@52959|Polaribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
HKD3_k127_2468521_0	1122176.KB903560_gene3551	1.052e-284	885.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HKD3_k127_2468521_6	1122176.KB903560_gene3552	1.315e-49	186.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1IQZH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
HKD3_k127_2468521_4	1168034.FH5T_09710	6.801e-72	270.0	COG1287@1|root,COG1287@2|Bacteria,4NUWQ@976|Bacteroidetes	976|Bacteroidetes	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2468521_5	760192.Halhy_5350	7.34e-55	205.0	COG3963@1|root,COG3963@2|Bacteria,4PP1W@976|Bacteroidetes,1IXSI@117747|Sphingobacteriia	976|Bacteroidetes	I	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HKD3_k127_2468521_8	1121912.AUHD01000013_gene922	7.424e-07	56.0	COG2963@1|root,COG2963@2|Bacteria,4NQGJ@976|Bacteroidetes,1I2UE@117743|Flavobacteriia	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28
HKD3_k127_2468521_3	926556.Echvi_4187	6.586e-79	272.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,47PK2@768503|Cytophagia	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
HKD3_k127_247113_2	1123278.KB893571_gene2225	8.067e-23	104.0	COG1577@1|root,COG1874@1|root,COG2374@1|root,COG2911@1|root,COG5492@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG2374@2|Bacteria,COG2911@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	mvaK2	-	2.7.1.36,2.7.4.2,3.1.3.5,3.2.1.97	ko:K00869,ko:K00938,ko:K01081,ko:K07004,ko:K17624	ko00230,ko00240,ko00760,ko00900,ko01100,ko01110,ko01130,ko04146,map00230,map00240,map00760,map00900,map01100,map01110,map01130,map04146	M00095	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02245,R02323,R02719,R03245,R03346	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	GH101	-	GHMP_kinases_C,GHMP_kinases_N,NPCBM,NPCBM_assoc
HKD3_k127_247113_0	760192.Halhy_3644	9.231e-262	845.0	COG0823@1|root,COG2831@1|root,COG0823@2|Bacteria,COG2831@2|Bacteria,4PNV1@976|Bacteroidetes,1IV8M@117747|Sphingobacteriia	976|Bacteroidetes	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HKD3_k127_247113_1	1499967.BAYZ01000037_gene2451	6.955e-38	146.0	COG0614@1|root,COG0614@2|Bacteria,2NRFM@2323|unclassified Bacteria	2|Bacteria	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	PDDEXK_3
HKD3_k127_2472514_29	1229276.DI53_2618	2.775e-07	53.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD3_k127_2472514_8	1317122.ATO12_21965	2.642e-125	410.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia,2YHPC@290174|Aquimarina	976|Bacteroidetes	J	S4 RNA-binding domain	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_2472514_18	761193.Runsl_0596	2.713e-82	286.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,47K6Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
HKD3_k127_2472514_15	1122179.KB890468_gene449	6.943e-92	308.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1IPXY@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD3_k127_2472514_11	1122176.KB903609_gene5144	5.228e-114	398.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1IPP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD3_k127_2472514_21	485918.Cpin_1675	2.484e-48	183.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1IQKS@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_2472514_17	1203611.KB894544_gene2053	1.601e-82	284.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,2FNES@200643|Bacteroidia,22U40@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HKD3_k127_2472514_24	760192.Halhy_0274	6.106e-38	159.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,1IYSE@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
HKD3_k127_2472514_9	1122176.KB903536_gene1819	9.024e-122	399.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1IQI3@117747|Sphingobacteriia	976|Bacteroidetes	E	Asparaginase	iaaA	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
HKD3_k127_2472514_0	760192.Halhy_0934	3.05e-220	710.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1IP87@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD3_k127_2472514_14	929556.Solca_3168	2.257e-99	336.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1IR57@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_2472514_25	180281.CPCC7001_2185	5.997e-34	141.0	COG1043@1|root,COG1043@2|Bacteria,1G1V3@1117|Cyanobacteria,22SDN@167375|Cyanobium	1117|Cyanobacteria	I	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iJN678.lpxA	Acetyltransf_11,Hexapep
HKD3_k127_2472514_12	313606.M23134_02020	6.146e-105	359.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47J92@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_2472514_19	760192.Halhy_0370	2.769e-80	286.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1IP8T@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_2472514_22	925409.KI911562_gene2691	1.831e-46	180.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD3_k127_2472514_26	1122176.KB903538_gene1494	1.888e-26	114.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1IT29@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
HKD3_k127_2472514_31	984262.SGRA_3036	2.852e-05	57.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria	2|Bacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0050896	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	AAA_11,AAA_12,AAA_30,DUF3427,Helicase_C,ResIII
HKD3_k127_2472514_27	926562.Oweho_1134	5.452e-11	72.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_8
HKD3_k127_2472514_2	760192.Halhy_5396	1.352e-158	517.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,HHH_8,PHP
HKD3_k127_2472514_20	1313421.JHBV01000007_gene4309	2.606e-50	185.0	COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,1ITRS@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
HKD3_k127_2472514_16	880074.BARVI_10965	1.601e-88	304.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,2FM4R@200643|Bacteroidia,22WQZ@171551|Porphyromonadaceae	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD3_k127_2472514_23	1123242.JH636435_gene1221	1.512e-38	156.0	COG0580@1|root,COG0580@2|Bacteria,2IZDN@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
HKD3_k127_2472514_5	1122176.KB903531_gene3044	8.673e-130	429.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,1IQ4K@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
HKD3_k127_2472514_4	1185876.BN8_03946	1.8e-131	434.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HKD3_k127_2472514_10	1122176.KB903574_gene4816	1.962e-121	415.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1INMF@117747|Sphingobacteriia	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
HKD3_k127_2472514_3	760192.Halhy_4849	3.763e-149	480.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1IQ8U@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD3_k127_2472514_7	485918.Cpin_1981	2.565e-125	419.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1IQVW@117747|Sphingobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2472514_6	1313421.JHBV01000035_gene2518	1.734e-127	413.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD3_k127_2472514_1	1122176.KB903534_gene2248	1.002e-161	520.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_2472514_13	1122176.KB903546_gene1027	1.392e-100	362.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,MAM,UnbV_ASPIC,VCBS,fn3
HKD3_k127_2480055_3	1122179.KB890422_gene2242	7.855e-23	97.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1IQ4T@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
HKD3_k127_2480055_2	1229276.DI53_1806	2.552e-25	122.0	2C5U1@1|root,2Z80K@2|Bacteria,4NG4G@976|Bacteroidetes,1IQ1S@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2480055_0	555500.I215_11958	3.233e-276	869.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HX6P@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_2480055_1	1123008.KB905694_gene1566	3.383e-89	299.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,2FSU3@200643|Bacteroidia,231RU@171551|Porphyromonadaceae	976|Bacteroidetes	KP	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD3_k127_2480055_4	1002367.HMPREF0673_02349	6.036e-06	55.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,2G2R1@200643|Bacteroidia	976|Bacteroidetes	O	Peptidase, S8 S53 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_2485724_0	1239962.C943_04539	8.937e-92	306.0	COG1136@1|root,COG1136@2|Bacteria,4NE65@976|Bacteroidetes,47KXA@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_2485724_3	1288826.MSNKSG1_14212	8.703e-37	150.0	2DE7S@1|root,2ZKW3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2485724_1	929713.NIASO_06975	2.64e-63	244.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI1V@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
HKD3_k127_2485724_2	1166018.FAES_3457	8.714e-39	149.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2487763_3	935845.JADQ01000039_gene2378	7.927e-57	220.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,4HFTF@91061|Bacilli,26QP3@186822|Paenibacillaceae	91061|Bacilli	S	beta-phosphoglucomutase	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD3_k127_2487763_0	391596.PBAL39_08594	1.904e-293	918.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IRII@117747|Sphingobacteriia	976|Bacteroidetes	G	phosphorylase	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
HKD3_k127_2487763_4	1305737.JAFX01000001_gene2708	5.94e-55	206.0	COG2197@1|root,COG2197@2|Bacteria,4NP2G@976|Bacteroidetes,47XF9@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2487763_5	1250005.PHEL85_3394	1.028e-50	202.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
HKD3_k127_2487763_1	1033732.CAHI01000030_gene823	4.882e-157	525.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia,22UZK@171550|Rikenellaceae	976|Bacteroidetes	F	Adenylosuccinate lyase C-terminal	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
HKD3_k127_2487763_6	1173028.ANKO01000116_gene5746	2.632e-23	115.0	COG3266@1|root,COG3266@2|Bacteria,1GBMG@1117|Cyanobacteria,1HENX@1150|Oscillatoriales	1117|Cyanobacteria	I	Interleukin-like EMT inducer	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,ILEI
HKD3_k127_2487763_2	471854.Dfer_1279	2.569e-107	352.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_2488951_6	1122179.KB890431_gene4189	2.72e-41	155.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_2488951_7	760192.Halhy_4324	1.638e-30	126.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HKD3_k127_2488951_9	1239962.C943_03596	1.494e-07	56.0	2DYCZ@1|root,3496N@2|Bacteria,4P6C5@976|Bacteroidetes,47W8C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HKD3_k127_2488951_8	1123276.KB893260_gene2605	9.317e-26	117.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia	976|Bacteroidetes	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
HKD3_k127_2488951_0	1122176.KB903537_gene1690	3.388e-165	556.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1IQQP@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
HKD3_k127_2488951_4	760192.Halhy_1882	4.01e-59	216.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1IT7G@117747|Sphingobacteriia	976|Bacteroidetes	M	peptidase M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_2488951_3	760192.Halhy_1881	1.398e-68	237.0	COG0241@1|root,COG0241@2|Bacteria,4PP1D@976|Bacteroidetes	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2488951_5	1121957.ATVL01000006_gene3145	7.238e-53	199.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,47KA1@768503|Cytophagia	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
HKD3_k127_2488951_1	1313421.JHBV01000030_gene2168	3.731e-109	374.0	COG0747@1|root,COG0747@2|Bacteria,4PP5D@976|Bacteroidetes,1J0ZS@117747|Sphingobacteriia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD3_k127_2488951_2	1122179.KB890445_gene4970	1.769e-71	259.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1IRI6@117747|Sphingobacteriia	976|Bacteroidetes	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD3_k127_2496027_0	1122176.KB903555_gene3749	6.063e-272	859.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_2496027_1	926549.KI421517_gene1261	1.954e-53	196.0	COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,47QQR@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
HKD3_k127_2496557_0	760192.Halhy_4135	1.655e-115	376.0	COG4947@1|root,COG4947@2|Bacteria,4NJWM@976|Bacteroidetes,1IVCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_2496557_2	1123257.AUFV01000007_gene346	1.649e-18	93.0	COG1714@1|root,COG1714@2|Bacteria,1R6WK@1224|Proteobacteria,1RYVD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD3_k127_2496557_1	865937.Gilli_2609	1.558e-29	122.0	arCOG10456@1|root,2ZA6T@2|Bacteria,4NGZ2@976|Bacteroidetes,1HXIA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2518748_1	1123037.AUDE01000006_gene1047	8.407e-203	661.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD,Sortilin-Vps10,TSP_3
HKD3_k127_2518748_3	1122605.KB893637_gene3157	4.267e-75	257.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IRJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
HKD3_k127_2518748_4	929713.NIASO_09040	5.418e-72	259.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,1IPMP@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
HKD3_k127_2518748_7	324925.Ppha_1113	3.581e-13	74.0	2ESXY@1|root,33KG8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2518748_0	945713.IALB_3112	0.0	1394.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_2518748_5	388413.ALPR1_09023	1.059e-59	213.0	2C7HJ@1|root,31BFZ@2|Bacteria,4NRGQ@976|Bacteroidetes,47WSM@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_2518748_2	1406840.Q763_11580	1.623e-112	370.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia,2NTFX@237|Flavobacterium	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
HKD3_k127_2518748_6	980584.AFPB01000163_gene2261	1.386e-22	108.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia,4062B@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Histidinol dehydrogenase	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HKD3_k127_2525412_5	1297742.A176_05728	4.886e-14	85.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_2525412_6	1237149.C900_01386	6.23e-13	81.0	28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,47N1W@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein SusF_SusE	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
HKD3_k127_2525412_3	1166018.FAES_3457	9.255e-58	212.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2525412_1	1227739.Hsw_0520	9.346e-89	327.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_2525412_0	1048983.EL17_21265	1.916e-134	444.0	COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231	-	-	-	ko00000,ko00001,ko02000	2.A.21,2.A.21.8	-	-	HD_4,SSF
HKD3_k127_2525412_2	760192.Halhy_5767	1.321e-73	255.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IRNA@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD3_k127_2535498_3	1121373.KB903621_gene1841	4.475e-14	73.0	2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,47SRN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
HKD3_k127_2535498_2	1121875.KB907547_gene2995	4.965e-68	246.0	COG2067@1|root,COG2067@2|Bacteria,4NX18@976|Bacteroidetes,1I5D9@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2535498_0	760192.Halhy_6127	7.851e-161	516.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1IR3Y@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HKD3_k127_2535498_1	984262.SGRA_2772	4.241e-103	338.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,1IPFB@117747|Sphingobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_25671_0	1380384.JADN01000007_gene1591	0.0	1215.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_25671_1	1356852.N008_21370	2.851e-25	108.0	2DNNF@1|root,32Y92@2|Bacteria,4PMHZ@976|Bacteroidetes,47YIV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2596073_0	1392498.JQLH01000001_gene3097	1.046e-273	859.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,1INAV@117743|Flavobacteriia,2PI0U@252356|Maribacter	976|Bacteroidetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD3_k127_2596073_1	1499967.BAYZ01000009_gene5315	3.772e-07	53.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07216,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	AAA_16,GAF,GAF_2,Guanylate_cyc,HATPase_c,Hemerythrin,HisKA,PAS,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE
HKD3_k127_2603313_0	1123277.KB893180_gene2414	8.103e-208	661.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47KRU@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
HKD3_k127_2603313_3	266748.HY04_11780	1.673e-31	129.0	COG0454@1|root,COG0456@2|Bacteria,4NSPT@976|Bacteroidetes,1I4MD@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
HKD3_k127_2603313_2	700598.Niako_0935	1.46e-48	181.0	COG3631@1|root,COG3631@2|Bacteria,4P470@976|Bacteroidetes	976|Bacteroidetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2603313_1	1408433.JHXV01000009_gene1363	9.189e-51	198.0	COG0596@1|root,COG0596@2|Bacteria,4PNUJ@976|Bacteroidetes,1I9ER@117743|Flavobacteriia,2PBQD@246874|Cryomorphaceae	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD3_k127_2619045_3	1122176.KB903560_gene3568	5.94e-21	95.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1IRUS@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_2619045_2	1122179.KB890413_gene4723	9.7e-45	166.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes	976|Bacteroidetes	J	Translation initiation inhibitor, yjgF family	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
HKD3_k127_2619045_1	1122176.KB903587_gene4462	9.418e-127	422.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1IPQV@117747|Sphingobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
HKD3_k127_2619045_0	1313301.AUGC01000003_gene2146	9.781e-146	477.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_267714_1	760192.Halhy_4953	1.509e-109	360.0	COG0025@1|root,COG0025@2|Bacteria,4NMV8@976|Bacteroidetes	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD3_k127_267714_3	743721.Psesu_0216	9.298e-27	113.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1SWYN@1236|Gammaproteobacteria,1X8Q4@135614|Xanthomonadales	135614|Xanthomonadales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD3_k127_267714_0	929703.KE386491_gene1877	2.647e-184	612.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,47M6U@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HTH_18,HisKA_2,Reg_prop,Response_reg,SpoIIE,Y_Y_Y
HKD3_k127_267714_2	906888.JCM19314_1533	5.972e-44	183.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia,3HKV5@363408|Nonlabens	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
HKD3_k127_267714_4	1122176.KB903543_gene691	3.472e-20	106.0	COG0457@1|root,COG0457@2|Bacteria,4NND8@976|Bacteroidetes	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_2723683_1	1123008.KB905695_gene2615	2.15e-92	310.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,2FNY2@200643|Bacteroidia,22WRH@171551|Porphyromonadaceae	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD3_k127_2723683_2	172045.KS04_08945	9.573e-67	237.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1HXHW@117743|Flavobacteriia,34PIA@308865|Elizabethkingia	976|Bacteroidetes	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
HKD3_k127_2723683_0	760192.Halhy_5818	4.835e-129	428.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HKD3_k127_2723683_4	1123276.KB893301_gene4323	7.087e-08	61.0	2DR38@1|root,339ZC@2|Bacteria,4NY0S@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2723683_3	1123276.KB893290_gene5210	3.877e-60	219.0	COG5295@1|root,COG5295@2|Bacteria,4NNAP@976|Bacteroidetes,47S88@768503|Cytophagia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2734901_1	1183438.GKIL_2917	3.618e-96	329.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_2734901_0	760192.Halhy_4420	3.462e-171	547.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD3_k127_2734901_2	357808.RoseRS_0220	9.411e-67	241.0	COG0451@1|root,COG0451@2|Bacteria,2GAZF@200795|Chloroflexi,374ZI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD
HKD3_k127_2748035_0	1216967.L100_04002	3.356e-139	452.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia,34PNJ@308865|Elizabethkingia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HKD3_k127_2748035_1	1313301.AUGC01000007_gene633	5.845e-40	156.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_2765015_1	1121890.AUDO01000009_gene21	8.188e-21	100.0	COG1280@1|root,COG1280@2|Bacteria,4NRV8@976|Bacteroidetes,1HY8C@117743|Flavobacteriia,2NU5C@237|Flavobacterium	976|Bacteroidetes	E	Lysine transporter LysE	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_2765015_0	1123277.KB893194_gene5825	6.849e-64	227.0	COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes,47MCV@768503|Cytophagia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
HKD3_k127_2766154_0	1122179.KB890436_gene1267	4.715e-177	584.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
HKD3_k127_2790473_0	1122176.KB903554_gene3884	4.112e-97	332.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2790473_2	1434325.AZQN01000001_gene272	6.174e-48	188.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43,fn3
HKD3_k127_2790473_3	1550091.JROE01000002_gene709	1.196e-06	59.0	2E6P5@1|root,3319I@2|Bacteria,4NWR9@976|Bacteroidetes,1IUKH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2790473_1	760192.Halhy_4953	2.939e-80	271.0	COG0025@1|root,COG0025@2|Bacteria,4NMV8@976|Bacteroidetes	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD3_k127_2870131_1	1122176.KB903531_gene2944	9.377e-144	465.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_2870131_4	1122176.KB903531_gene2945	4.292e-78	282.0	COG1073@1|root,COG1073@2|Bacteria,4NMVZ@976|Bacteroidetes	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2870131_0	760192.Halhy_0935	7.917e-164	538.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1IQP4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM N-terminal double-transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
HKD3_k127_2870131_3	1122605.KB893637_gene3162	2.088e-94	325.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_2870131_7	1185876.BN8_06691	1.769e-13	77.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,47QS1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
HKD3_k127_2870131_2	929556.Solca_0935	1.084e-123	404.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1IPAW@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_2870131_5	1237149.C900_04059	3.507e-50	187.0	COG4539@1|root,COG4539@2|Bacteria,4NQIX@976|Bacteroidetes,47Q6B@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
HKD3_k127_2870131_6	745718.JADT01000006_gene706	1.164e-42	167.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1HX2G@117743|Flavobacteriia	976|Bacteroidetes	S	O-Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD3_k127_2888467_1	1071679.BG57_32355	6.463e-147	472.0	COG3408@1|root,COG3408@2|Bacteria,1QUN2@1224|Proteobacteria,2WHH3@28216|Betaproteobacteria,1KIP3@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
HKD3_k127_2888467_0	1042326.AZNV01000031_gene3669	5.562e-210	667.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,2UQIK@28211|Alphaproteobacteria,4BIGR@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
HKD3_k127_2888467_2	1379270.AUXF01000007_gene997	1.193e-94	323.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_2888467_3	1121918.ARWE01000001_gene3108	9.071e-71	252.0	COG0580@1|root,COG0580@2|Bacteria,1MZ47@1224|Proteobacteria	1224|Proteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
HKD3_k127_2888467_4	319795.Dgeo_1304	2.899e-17	87.0	COG0166@1|root,COG0166@2|Bacteria,1WIGN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD3_k127_2916411_1	1089547.KB913013_gene4257	1.229e-07	53.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,47KSA@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_2916411_2	1007103.AFHW01000140_gene3965	2.66e-05	55.0	COG3291@1|root,COG4724@1|root,COG3291@2|Bacteria,COG4724@2|Bacteria,1TPGB@1239|Firmicutes,4HDJJ@91061|Bacilli,26RF7@186822|Paenibacillaceae	91061|Bacilli	G	endo-beta-N-acetylglucosaminidase	-	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Big_3,F5_F8_type_C,FIVAR,G5,Glyco_hydro_85,Gram_pos_anchor,PKD,YSIRK_signal
HKD3_k127_2916411_0	1124780.ANNU01000030_gene1122	4.285e-108	360.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,47JXY@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase family 16	bglA	-	3.2.1.73	ko:K01216	-	-	-	-	ko00000,ko01000	-	-	-	GDPD,Glyco_hydro_16
HKD3_k127_292944_1	760192.Halhy_4165	1.793e-153	490.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1INUM@117747|Sphingobacteriia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD3_k127_292944_3	1408433.JHXV01000009_gene1229	3.709e-32	134.0	29F7N@1|root,3025B@2|Bacteria,4NNR8@976|Bacteroidetes,1I26I@117743|Flavobacteriia,2PBTS@246874|Cryomorphaceae	976|Bacteroidetes	S	serine protease	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
HKD3_k127_292944_0	1004149.AFOE01000003_gene2210	1.507e-166	543.0	COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,1HXFH@117743|Flavobacteriia	976|Bacteroidetes	S	SPFH Band 7 PHB domain protein	yqiK	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
HKD3_k127_292944_2	700598.Niako_5038	4.215e-85	284.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_2941010_3	984262.SGRA_0326	2.017e-93	334.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1INZH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_2941010_1	984262.SGRA_1630	9.797e-115	391.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
HKD3_k127_2941010_4	153721.MYP_2527	6.581e-85	305.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
HKD3_k127_2941010_2	1122179.KB890440_gene996	3.47e-100	337.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1IWT1@117747|Sphingobacteriia	976|Bacteroidetes	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
HKD3_k127_2941010_0	760192.Halhy_4709	3.579e-176	561.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
HKD3_k127_3001121_1	700598.Niako_0294	2.109e-105	346.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1IQCX@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HKD3_k127_3001121_3	929562.Emtol_2856	6.313e-20	98.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47R8S@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_3001121_2	89462.XP_006043973.1	2.054e-51	204.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,483KS@7711|Chordata,48WWG@7742|Vertebrata,3J1P4@40674|Mammalia,4IX5G@91561|Cetartiodactyla	33208|Metazoa	S	Transmembrane and TPR repeat-containing protein	TMTC4	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
HKD3_k127_3001121_0	760192.Halhy_4626	1.593e-121	397.0	COG1858@1|root,COG1858@2|Bacteria,4NGX7@976|Bacteroidetes	976|Bacteroidetes	P	Pfam Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
HKD3_k127_3027146_3	760192.Halhy_5883	2.578e-42	167.0	COG1404@1|root,COG1404@2|Bacteria,4NSXZ@976|Bacteroidetes	976|Bacteroidetes	O	Subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
HKD3_k127_3027146_2	760192.Halhy_5882	1.273e-156	501.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_3027146_1	1122176.KB903619_gene5381	8.629e-184	581.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,1IPX5@117747|Sphingobacteriia	976|Bacteroidetes	G	Fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HKD3_k127_3027146_4	1122176.KB903576_gene4969	1.423e-32	134.0	2E562@1|root,32ZYV@2|Bacteria,4NVMY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3027146_0	1122176.KB903538_gene1503	8.893e-264	837.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1IP7W@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD3_k127_3087831_1	1121373.KB903664_gene2651	4.86e-135	458.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3087831_2	1347342.BN863_9110	3.866e-38	147.0	2A3Y3@1|root,30SGF@2|Bacteria,4NZA3@976|Bacteroidetes,1IIYA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3087831_0	760192.Halhy_0271	1.014e-153	501.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1INRC@117747|Sphingobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HKD3_k127_3087831_3	4641.GSMUA_Achr4P03100_001	8.285e-08	55.0	COG1385@1|root,2QPPV@2759|Eukaryota,37PHM@33090|Viridiplantae,3G8B1@35493|Streptophyta,3KNC7@4447|Liliopsida	35493|Streptophyta	J	RNA methyltransferase	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HKD3_k127_310491_0	1122176.KB903532_gene2674	1.036e-175	560.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,1IW0D@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_310491_1	1122176.KB903532_gene2675	3.057e-94	314.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
HKD3_k127_3227984_1	760192.Halhy_4033	3.399e-251	804.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1J0XF@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_3227984_0	760192.Halhy_3611	0.0	1486.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD3_k127_3229312_3	1122176.KB903565_gene3418	1.558e-59	223.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,1INTG@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
HKD3_k127_3229312_7	1122176.KB903565_gene3417	6.979e-40	152.0	COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional repressor, CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HKD3_k127_3229312_5	1392490.JHZX01000001_gene2660	7.296e-48	182.0	COG3137@1|root,COG3137@2|Bacteria,4NJH6@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
HKD3_k127_3229312_2	1121898.Q766_00110	4.136e-60	211.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2NWCA@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD3_k127_3229312_4	760192.Halhy_3066	9.053e-57	212.0	COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1IZTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
HKD3_k127_3229312_1	1122605.KB893646_gene107	4.32e-132	428.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1IQW6@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
HKD3_k127_3229312_0	1122176.KB903550_gene4281	0.0	1051.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
HKD3_k127_3229312_10	153721.MYP_1664	3.293e-27	120.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
HKD3_k127_3229312_9	1123277.KB893177_gene3659	3.137e-30	128.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,47Q9Q@768503|Cytophagia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
HKD3_k127_3229312_6	760192.Halhy_2595	2.616e-40	151.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1ISXQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_3229312_8	1122179.KB890414_gene1732	2.15e-35	143.0	COG4783@1|root,COG4783@2|Bacteria,4PP1I@976|Bacteroidetes,1J0X1@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
HKD3_k127_3259276_0	317936.Nos7107_1366	1.999e-206	691.0	COG0515@1|root,COG0642@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	4.6.1.1	ko:K01768,ko:K07216	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,PAS_9,Pkinase,Response_reg
HKD3_k127_3259276_3	1121904.ARBP01000005_gene4824	1.292e-31	128.0	2DPIW@1|root,332A0@2|Bacteria,4NUNN@976|Bacteroidetes,47T5G@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3259276_2	760192.Halhy_5178	7.677e-57	211.0	COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_3259276_4	1048983.EL17_01630	3.868e-07	61.0	2DQSW@1|root,338FU@2|Bacteria,4NYF2@976|Bacteroidetes,47S19@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
HKD3_k127_3259276_1	1077285.AGDG01000046_gene2791	4.473e-131	446.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia,4AKRS@815|Bacteroidaceae	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_327378_2	929703.KE386491_gene24	1.142e-15	80.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,47JY8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HKD3_k127_327378_1	1089547.KB913013_gene967	9.731e-156	541.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_327378_0	755732.Fluta_3935	0.0	1408.0	COG1572@1|root,COG1572@2|Bacteria,4PMCS@976|Bacteroidetes,1I8GH@117743|Flavobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Laminin_G_3
HKD3_k127_335039_26	1122179.KB890449_gene120	2.731e-24	104.0	COG1314@1|root,COG1314@2|Bacteria,4PJ7H@976|Bacteroidetes,1IZQE@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HKD3_k127_335039_24	760192.Halhy_5730	2.105e-42	157.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1ITF1@117747|Sphingobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD3_k127_335039_2	1122176.KB903531_gene2882	7.872e-284	878.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD3_k127_335039_9	760192.Halhy_6523	2.89e-123	405.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_335039_18	1385513.N780_02650	2.547e-51	188.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,2YABA@289201|Pontibacillus	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HKD3_k127_335039_10	1122176.KB903531_gene2774	5.012e-100	336.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD3_k127_335039_22	1122176.KB903531_gene2775	4.83e-43	165.0	2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,1J0YX@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_335039_14	1122176.KB903598_gene4600	5.817e-75	259.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
HKD3_k127_335039_20	760192.Halhy_5367	2.269e-47	178.0	COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,1ITRS@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_7
HKD3_k127_335039_11	273121.WS0557	3.099e-91	306.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2YMMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HKD3_k127_335039_27	1122179.KB890497_gene2775	2.275e-22	107.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1ITGX@117747|Sphingobacteriia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
HKD3_k127_335039_17	760192.Halhy_1175	2.033e-52	189.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1IU44@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_335039_19	1123070.KB899256_gene2174	8.854e-51	185.0	COG2322@1|root,COG2322@2|Bacteria,46SZT@74201|Verrucomicrobia,2IUT2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF420
HKD3_k127_335039_8	1122176.KB903531_gene2794	1.925e-131	426.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1INPX@117747|Sphingobacteriia	976|Bacteroidetes	C	oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_335039_16	1122176.KB903531_gene2795	1.223e-54	207.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1IST1@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_335039_13	1122176.KB903531_gene2796	1.26e-78	272.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1IRUR@117747|Sphingobacteriia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
HKD3_k127_335039_1	1122176.KB903531_gene2797	0.0	1007.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1IPZE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HKD3_k127_335039_4	760192.Halhy_4875	1.048e-190	607.0	COG1622@1|root,COG2885@1|root,COG1622@2|Bacteria,COG2885@2|Bacteria,4NFNF@976|Bacteroidetes,1IPEE@117747|Sphingobacteriia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
HKD3_k127_335039_6	760192.Halhy_4874	1.113e-163	524.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1IPBN@117747|Sphingobacteriia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_335039_12	760192.Halhy_4873	2e-83	294.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
HKD3_k127_335039_15	1122176.KB903531_gene2801	1.515e-69	242.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1ITKW@117747|Sphingobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
HKD3_k127_335039_3	1122176.KB903531_gene2802	3.829e-256	796.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1INKZ@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HKD3_k127_335039_0	1122176.KB903531_gene2803	0.0	1136.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1IPWZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
HKD3_k127_335039_5	760192.Halhy_4869	3.971e-180	575.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1IPBV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
HKD3_k127_335039_7	997296.PB1_13449	3.169e-142	454.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,1ZAUT@1386|Bacillus	91061|Bacilli	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HKD3_k127_335039_21	1484460.JSWG01000001_gene2089	1.466e-44	185.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NKQV@976|Bacteroidetes,1HYSN@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_335039_23	1122176.KB903531_gene2892	6.356e-43	161.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
HKD3_k127_336448_0	880071.Fleli_4087	1.798e-209	694.0	COG0515@1|root,COG2203@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,4PM99@976|Bacteroidetes,47KKS@768503|Cytophagia	976|Bacteroidetes	KLT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,Pkinase,SpoIIE
HKD3_k127_336448_4	1242864.D187_001007	6.794e-30	136.0	2DB8Y@1|root,2Z7TF@2|Bacteria,1NCMY@1224|Proteobacteria,43B9S@68525|delta/epsilon subdivisions,2X6NX@28221|Deltaproteobacteria,2Z3BY@29|Myxococcales	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
HKD3_k127_336448_3	1121897.AUGO01000007_gene484	1.459e-66	237.0	COG2230@1|root,COG2230@2|Bacteria,4NH6J@976|Bacteroidetes,1HYYX@117743|Flavobacteriia	976|Bacteroidetes	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_11
HKD3_k127_336448_5	471854.Dfer_3380	5.168e-06	59.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,47Q5Z@768503|Cytophagia	976|Bacteroidetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HKD3_k127_336448_1	1122176.KB903549_gene1256	1.594e-187	614.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_336448_2	323261.Noc_1396	2.161e-97	324.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN3T@1236|Gammaproteobacteria,1WXD8@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_3516456_15	521011.Mpal_1421	2.431e-13	74.0	COG3291@1|root,COG3391@1|root,arCOG02508@2157|Archaea,arCOG03563@2157|Archaea,2Y2RX@28890|Euryarchaeota,2NAHT@224756|Methanomicrobia	224756|Methanomicrobia	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PKD
HKD3_k127_3516456_5	1122176.KB903550_gene4304	2.51e-67	235.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,1IRYC@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HKD3_k127_3516456_12	760192.Halhy_2150	6.128e-40	151.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1ISQF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3516456_6	760192.Halhy_6197	5.877e-55	216.0	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1IT68@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_10,TPR_12,TPR_8
HKD3_k127_3516456_9	760192.Halhy_6196	2.118e-46	174.0	COG2197@1|root,COG2197@2|Bacteria,4NUSF@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_3516456_8	991.IW20_20215	1.865e-48	183.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
HKD3_k127_3516456_2	1122179.KB890425_gene3338	2.946e-102	338.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HKD3_k127_3516456_1	984262.SGRA_3310	1.305e-213	693.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1IQXN@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
HKD3_k127_3516456_3	760192.Halhy_3347	8.642e-74	266.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
HKD3_k127_3516456_13	760192.Halhy_3348	3.06e-23	104.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1IUKR@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3516456_11	760192.Halhy_3350	3.663e-43	163.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1IQKN@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_3516456_7	1349785.BAUG01000012_gene921	1.037e-50	185.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1I28N@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
HKD3_k127_3516456_10	1270193.JARP01000001_gene3095	8.97e-44	165.0	COG0824@1|root,COG0824@2|Bacteria,4NK6Y@976|Bacteroidetes,1I2SF@117743|Flavobacteriia,2NVXC@237|Flavobacterium	976|Bacteroidetes	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2,Acyl-ACP_TE
HKD3_k127_3516456_0	929713.NIASO_13960	3.19e-232	740.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HKD3_k127_3516456_4	395493.BegalDRAFT_1056	7.732e-69	243.0	COG1432@1|root,COG1432@2|Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD,NYN
HKD3_k127_3516456_14	1197477.IA57_01955	6.024e-18	89.0	COG2050@1|root,COG2050@2|Bacteria,4NNXM@976|Bacteroidetes,1I1ZV@117743|Flavobacteriia	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
HKD3_k127_357199_0	1122176.KB903532_gene2719	0.0	1156.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1IQY4@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
HKD3_k127_357199_1	760192.Halhy_4497	7.292e-89	296.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1IRTH@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD3_k127_357199_2	1519464.HY22_04545	7.342e-47	191.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSII_BNR,fn3
HKD3_k127_3614685_4	1122176.KB903619_gene5365	7.49e-96	326.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD3_k127_3614685_1	1122176.KB903619_gene5364	0.0	1023.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HKD3_k127_3614685_8	1484460.JSWG01000003_gene799	3.603e-42	160.0	COG0589@1|root,COG0589@2|Bacteria,4NNMW@976|Bacteroidetes,1IIQF@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_3614685_7	1484460.JSWG01000001_gene2155	1.658e-43	171.0	2BSEF@1|root,32MGE@2|Bacteria,4NK41@976|Bacteroidetes,1HYCH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3614685_3	1178825.ALIH01000010_gene422	3.069e-185	590.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
HKD3_k127_3614685_0	1237149.C900_02615	0.0	1332.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_3614685_6	760192.Halhy_5126	2.186e-68	241.0	COG1428@1|root,COG1428@2|Bacteria,4PM5R@976|Bacteroidetes,1IXF2@117747|Sphingobacteriia	976|Bacteroidetes	F	Thymidylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD3_k127_3614685_9	1227739.Hsw_1195	5.149e-39	151.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,47QG8@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
HKD3_k127_3614685_5	1123278.KB893568_gene2090	5.611e-94	324.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,47KID@768503|Cytophagia	976|Bacteroidetes	J	RNA-binding PUA-like domain of methyltransferase RsmF	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
HKD3_k127_3614685_2	984262.SGRA_1771	1.075e-260	814.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
HKD3_k127_3691642_1	761193.Runsl_1513	5.347e-51	188.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,47JZC@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_3691642_0	760192.Halhy_1860	3.131e-235	769.0	COG4412@1|root,COG4412@2|Bacteria,4PM4A@976|Bacteroidetes,1IWTI@117747|Sphingobacteriia	976|Bacteroidetes	UW	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,FTP,PA,Peptidase_M36,Peptidase_M6
HKD3_k127_3696176_0	1408433.JHXV01000005_gene2257	1.432e-131	443.0	COG2931@1|root,COG2931@2|Bacteria,4P2B3@976|Bacteroidetes,1I8WB@117743|Flavobacteriia,2PBTD@246874|Cryomorphaceae	976|Bacteroidetes	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3696176_1	755732.Fluta_3064	1.464e-87	296.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1HY13@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_3703314_2	1122176.KB903537_gene1653	5.759e-34	134.0	COG2367@1|root,COG2367@2|Bacteria,4NHF9@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
HKD3_k127_3703314_0	1046627.BZARG_2330	6.986e-309	976.0	COG0574@1|root,COG0574@2|Bacteria,4NH4R@976|Bacteroidetes,1HWKY@117743|Flavobacteriia	976|Bacteroidetes	G	Pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
HKD3_k127_3703314_4	1086011.HJ01_03171	7.303e-28	117.0	2E3H7@1|root,32YFW@2|Bacteria,4NVEF@976|Bacteroidetes,1I52A@117743|Flavobacteriia,2NXWF@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3703314_7	755732.Fluta_3115	2.895e-15	83.0	2DZIM@1|root,32VBN@2|Bacteria,4NTG0@976|Bacteroidetes,1I4SS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3703314_5	1122605.KB893638_gene3455	6.204e-27	116.0	COG2608@1|root,COG2608@2|Bacteria,4NURN@976|Bacteroidetes,1IUCK@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HKD3_k127_3703314_3	1121285.AUFK01000012_gene1929	3.016e-30	124.0	COG0845@1|root,COG0845@2|Bacteria,4NSWM@976|Bacteroidetes,1I1UM@117743|Flavobacteriia,3ZUID@59732|Chryseobacterium	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
HKD3_k127_3703314_6	1317122.ATO12_03790	4.123e-23	109.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1I3FD@117743|Flavobacteriia,2YHTC@290174|Aquimarina	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_3703314_1	1123277.KB893216_gene4864	5.82e-42	178.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47V2C@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_3727759_0	1301098.PKB_4334	7.651e-119	393.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RTA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HKD3_k127_3733058_34	1121405.dsmv_2612	8.963e-41	156.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2MJ2T@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_3733058_20	1317122.ATO12_06075	1.626e-112	377.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1HXB7@117743|Flavobacteriia,2YH8B@290174|Aquimarina	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD3_k127_3733058_26	760192.Halhy_2661	8.163e-75	269.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1INKX@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD3_k127_3733058_32	517417.Cpar_1155	4.875e-45	176.0	COG3118@1|root,COG3118@2|Bacteria,1FDP7@1090|Chlorobi	1090|Chlorobi	O	PFAM Thioredoxin domain	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_20,Thioredoxin
HKD3_k127_3733058_37	760192.Halhy_2397	2.125e-27	115.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1ITU7@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
HKD3_k127_3733058_1	760192.Halhy_6353	0.0	1163.0	COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,1ISED@117747|Sphingobacteriia	976|Bacteroidetes	O	of the AAA class	-	-	-	-	-	-	-	-	-	-	-	-	AAA
HKD3_k127_3733058_35	760192.Halhy_0258	3.048e-33	140.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1IYC2@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD3_k127_3733058_3	760192.Halhy_6035	2.222e-288	899.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IPSM@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD3_k127_3733058_30	1408473.JHXO01000004_gene269	2.243e-53	198.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HKD3_k127_3733058_29	984262.SGRA_0358	4.048e-54	208.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1IQ5D@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HKD3_k127_3733058_19	760192.Halhy_5771	1.003e-113	381.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HKD3_k127_3733058_33	1229276.DI53_3183	2.013e-43	165.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1ISC5@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphoesterase PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_3733058_11	760192.Halhy_5806	6.15e-155	504.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD3_k127_3733058_16	1267211.KI669560_gene1996	8.369e-124	407.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD3_k127_3733058_27	1249634.D781_0007	5.363e-70	251.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria,400ED@613|Serratia	1236|Gammaproteobacteria	E	Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_3733058_24	760192.Halhy_6502	1.964e-89	302.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1IQ9S@117747|Sphingobacteriia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD3_k127_3733058_36	1122176.KB903598_gene4667	1.611e-27	113.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1IU7U@117747|Sphingobacteriia	976|Bacteroidetes	O	NifU-like domain	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
HKD3_k127_3733058_13	1122176.KB903598_gene4666	4.048e-148	477.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HKD3_k127_3733058_12	1122176.KB903554_gene4012	1.189e-152	487.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
HKD3_k127_3733058_25	1122176.KB903554_gene4013	1.862e-81	289.0	COG1361@1|root,COG1361@2|Bacteria,4NT4K@976|Bacteroidetes,1IZPA@117747|Sphingobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD3_k127_3733058_14	1122176.KB903609_gene5146	3.979e-139	454.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_3733058_5	1121904.ARBP01000010_gene2369	1.372e-210	678.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,47M2A@768503|Cytophagia	976|Bacteroidetes	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HKD3_k127_3733058_6	1122176.KB903532_gene2694	6.7e-191	602.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HKD3_k127_3733058_23	1122179.KB890418_gene3793	1.294e-90	316.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,1IRPR@117747|Sphingobacteriia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HKD3_k127_3733058_45	760192.Halhy_5124	0.0002404	51.0	COG1722@1|root,COG1722@2|Bacteria,4PJ5T@976|Bacteroidetes,1IZKQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	-	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HKD3_k127_3733058_2	984262.SGRA_2123	8.32e-321	1004.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1IR7Y@117747|Sphingobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HKD3_k127_3733058_4	1313421.JHBV01000024_gene4946	9.729e-213	693.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1IP4P@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_3733058_7	1122179.KB890442_gene1139	1.922e-182	582.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1IP0Q@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
HKD3_k127_3733058_31	926562.Oweho_2985	4.94e-49	181.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia,2PAU7@246874|Cryomorphaceae	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
HKD3_k127_3733058_44	459495.SPLC1_S570210	5.395e-07	62.0	COG1287@1|root,COG1287@2|Bacteria,1G1Q8@1117|Cyanobacteria,1HI3N@1150|Oscillatoriales	1117|Cyanobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3733058_15	760192.Halhy_4423	1.183e-128	431.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37,3.5.3.12	ko:K08589,ko:K10536	ko00330,ko01100,ko01503,map00330,map01100,map01503	-	R01416	RC00177	ko00000,ko00001,ko01000,ko01002	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
HKD3_k127_3733058_21	929704.Myrod_0793	1.445e-93	314.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1HYTE@117743|Flavobacteriia,47HX7@76831|Myroides	976|Bacteroidetes	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD3_k127_3733058_9	1392488.JHZY01000004_gene2329	3.724e-172	558.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1HY9Z@117743|Flavobacteriia,2XI0W@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HKD3_k127_3733058_0	1122176.KB903537_gene1711	0.0	1256.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IQCA@117747|Sphingobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
HKD3_k127_3733058_8	1122176.KB903537_gene1710	3.303e-173	550.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1IP47@117747|Sphingobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
HKD3_k127_3733058_17	760192.Halhy_5864	3.363e-118	389.0	COG0598@1|root,COG0598@2|Bacteria,4NGM7@976|Bacteroidetes,1IWM4@117747|Sphingobacteriia	976|Bacteroidetes	P	Mg2 transporter protein, CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD3_k127_3733058_40	1122176.KB903532_gene2611	1.479e-16	88.0	2DMRA@1|root,32T5V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3733058_18	1122176.KB903531_gene3079	2.528e-116	389.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1IPU4@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
HKD3_k127_3733058_10	760192.Halhy_5793	6.777e-159	516.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD3_k127_3733058_43	194867.ALBQ01000011_gene384	2.518e-07	54.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
HKD3_k127_3733058_41	865937.Gilli_1012	2.779e-14	77.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	3.1.21.3	ko:K01154,ko:K07461	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	GIY-YIG
HKD3_k127_3733058_22	338966.Ppro_1962	1.604e-92	313.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,43U0E@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_3733058_28	1165841.SULAR_03802	4.076e-69	256.0	COG4564@1|root,COG4564@2|Bacteria,1N7NM@1224|Proteobacteria,42W17@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM Cache	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	dCache_2,sCache_2
HKD3_k127_3733058_38	439235.Dalk_2070	7.747e-25	120.0	COG4564@1|root,COG4564@2|Bacteria	2|Bacteria	T	Single Cache domain 2	-	-	2.7.13.3	ko:K07647	ko02020,map02020	M00455	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,Cache_3-Cache_2,GAF,HATPase_c,HisKA,Hpt,PAS_3,Response_reg,dCache_2,sCache_2
HKD3_k127_3741506_0	1227739.Hsw_3202	2.393e-68	237.0	COG5549@1|root,COG5549@2|Bacteria,4NGSZ@976|Bacteroidetes,47SS0@768503|Cytophagia	976|Bacteroidetes	O	Dual-action HEIGH metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M57
HKD3_k127_3741506_1	760192.Halhy_2216	1.209e-32	137.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_3749248_5	1121899.Q764_11605	3.213e-52	188.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,1I2VM@117743|Flavobacteriia,2NWBY@237|Flavobacterium	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
HKD3_k127_3749248_1	925409.KI911562_gene2297	2.25e-172	549.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1IP6F@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
HKD3_k127_3749248_2	700598.Niako_4382	4.677e-162	513.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IPIY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	pabB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
HKD3_k127_3749248_3	1283300.ATXB01000001_gene2107	2.429e-101	336.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XE0H@135618|Methylococcales	135618|Methylococcales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD3_k127_3749248_6	1121920.AUAU01000021_gene2513	4.621e-37	143.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria	2|Bacteria	S	PFAM Iron-binding zinc finger CDGSH type	yjdI	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_19,zf-CDGSH
HKD3_k127_3749248_4	1122176.KB903550_gene4342	9.326e-70	243.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1IRZ1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD3_k127_3749248_0	760192.Halhy_3373	1.481e-180	592.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1IVTD@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component regulator propeller domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
HKD3_k127_3794857_4	1239962.C943_04091	3.835e-19	89.0	COG0745@1|root,COG0745@2|Bacteria,4NMAD@976|Bacteroidetes,47XIF@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_3794857_2	760192.Halhy_0310	4.126e-64	237.0	COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,1IWXD@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_3794857_3	1189612.A33Q_0621	9.243e-31	131.0	28J3Q@1|root,32URP@2|Bacteria,4NT50@976|Bacteroidetes,47R3P@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_3794857_1	761193.Runsl_2121	5.529e-190	626.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD3_k127_3794857_0	760192.Halhy_6398	7.043e-229	771.0	COG2885@1|root,COG3292@1|root,COG2885@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	M	chlorophyll binding	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
HKD3_k127_3795834_1	1122176.KB903576_gene4939	2.361e-140	456.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1IPX7@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3795834_0	760192.Halhy_4797	3.134e-276	894.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1IW9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
HKD3_k127_3796843_1	1313421.JHBV01000043_gene3107	5.216e-59	222.0	COG1520@1|root,COG2931@1|root,COG3291@1|root,COG4935@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI1E@976|Bacteroidetes,1IYUU@117747|Sphingobacteriia	976|Bacteroidetes	Q	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3796843_0	1185876.BN8_02240	6.823e-90	310.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47M2K@768503|Cytophagia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_3806860_0	1121271.AUCM01000007_gene3757	7.603e-121	394.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TQZY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1175 ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HKD3_k127_3806860_1	1121271.AUCM01000007_gene3756	7.444e-117	380.0	COG0395@1|root,COG0395@2|Bacteria,1MXEM@1224|Proteobacteria,2TUQV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	ycjP	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HKD3_k127_3818386_6	1123248.KB893314_gene3386	1.289e-22	108.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IVY8@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
HKD3_k127_3818386_3	760192.Halhy_2775	7.372e-57	201.0	COG3495@1|root,COG3495@2|Bacteria,4NTUM@976|Bacteroidetes,1J0DJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_3818386_7	1235803.C825_03907	5.001e-19	98.0	COG2348@1|root,COG2348@2|Bacteria,4NQ1R@976|Bacteroidetes,2FTKE@200643|Bacteroidia,22Y8E@171551|Porphyromonadaceae	976|Bacteroidetes	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
HKD3_k127_3818386_0	504487.JCM19302_2167	5.573e-177	573.0	COG5267@1|root,COG5267@2|Bacteria,4NJBN@976|Bacteroidetes,1I0QW@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
HKD3_k127_3818386_1	1178825.ALIH01000005_gene159	2.319e-154	501.0	COG4102@1|root,COG4102@2|Bacteria,4NJKZ@976|Bacteroidetes,1HY2C@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD3_k127_3818386_4	1178825.ALIH01000005_gene160	1.773e-47	185.0	2DICN@1|root,32UAX@2|Bacteria,4NU78@976|Bacteroidetes,1I4Y5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
HKD3_k127_3818386_5	1089547.KB913013_gene1868	5.077e-25	110.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,47RDS@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised P-loop hydrolase UPF0079	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD3_k127_3818386_2	1122176.KB903549_gene1254	1.526e-131	429.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD3_k127_3844176_4	697282.Mettu_2044	5.046e-18	91.0	2DQ3J@1|root,334KB@2|Bacteria,1NFUT@1224|Proteobacteria,1SH2X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3844176_2	1304865.JAGF01000001_gene3493	1.844e-190	626.0	COG2132@1|root,COG2866@1|root,COG2132@2|Bacteria,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,DUF4396
HKD3_k127_3844176_3	1304865.JAGF01000001_gene3492	3.996e-190	601.0	COG2132@1|root,COG2132@2|Bacteria,2IDXQ@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
HKD3_k127_3844176_1	1304865.JAGF01000001_gene3491	2.526e-198	630.0	COG2132@1|root,COG2132@2|Bacteria,2IAV7@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD3_k127_3844176_0	1304865.JAGF01000001_gene3490	0.0	1971.0	COG2132@1|root,COG2132@2|Bacteria,2H743@201174|Actinobacteria	201174|Actinobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	TIG,fn3_3
HKD3_k127_3861074_5	1469557.JSWF01000025_gene1400	5.51e-05	49.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
HKD3_k127_3861074_4	273068.TTE1752	4.818e-73	252.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,42EY8@68295|Thermoanaerobacterales	186801|Clostridia	F	TIGRFAM purine nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_3861074_2	391603.FBALC1_06773	7.923e-115	384.0	COG3174@1|root,COG3174@2|Bacteria,4NKP6@976|Bacteroidetes,1HYVZ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
HKD3_k127_3861074_1	760192.Halhy_6067	4.027e-131	470.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,Laminin_G_3,SprB
HKD3_k127_3861074_0	1121904.ARBP01000011_gene1483	1.34e-157	524.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47KRB@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
HKD3_k127_3861074_3	1121904.ARBP01000011_gene1484	6.072e-99	363.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47JE0@768503|Cytophagia	976|Bacteroidetes	M	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
HKD3_k127_3864571_6	1122176.KB903565_gene3294	1.056e-60	218.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HKD3_k127_3864571_8	1227739.Hsw_3412	3.934e-37	150.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
HKD3_k127_3864571_9	1122176.KB903565_gene3296	4.252e-37	143.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1ISS0@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HKD3_k127_3864571_0	760192.Halhy_3582	3.818e-286	893.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IQ2Z@117747|Sphingobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD3_k127_3864571_5	344747.PM8797T_16303	5.303e-62	215.0	COG0229@1|root,COG0229@2|Bacteria,2IZ8D@203682|Planctomycetes	203682|Planctomycetes	C	peptide-methionine (R)-S-oxide reductase	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
HKD3_k127_3864571_3	714943.Mucpa_3117	1.098e-102	351.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HKD3_k127_3864571_2	1454007.JAUG01000007_gene2145	1.741e-155	507.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HKD3_k127_3864571_1	929556.Solca_3729	1.692e-214	683.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
HKD3_k127_3864571_10	992406.RIA_1533	2.257e-33	132.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1I39R@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HKD3_k127_3864571_7	531844.FIC_01669	2.442e-41	160.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I26W@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HKD3_k127_3864571_4	755732.Fluta_1965	1.943e-73	250.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
HKD3_k127_3865595_1	760192.Halhy_0318	2.624e-58	206.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1ISEW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HKD3_k127_3865595_0	760192.Halhy_0317	4.385e-96	317.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HKD3_k127_3865595_2	468059.AUHA01000002_gene1083	1.108e-44	165.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1ISVI@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HKD3_k127_3872166_0	1210884.HG799469_gene14219	1.401e-282	892.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_3872166_3	760192.Halhy_2527	6.921e-76	266.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1IPT7@117747|Sphingobacteriia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
HKD3_k127_3872166_1	1169144.KB910935_gene1998	8.67e-129	432.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,1ZBB0@1386|Bacillus	91061|Bacilli	E	amino acid	yfnA	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_3872166_2	1282876.BAOK01000001_gene3509	7.779e-81	275.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Malic enzyme	MA20_02490	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
HKD3_k127_3891981_55	760192.Halhy_1454	8.316e-32	129.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD3_k127_3891981_67	1313301.AUGC01000003_gene1927	2.05e-05	50.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HKD3_k127_3891981_40	1122621.ATZA01000041_gene2658	2.917e-55	201.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1IRX6@117747|Sphingobacteriia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
HKD3_k127_3891981_66	1168034.FH5T_20345	4.491e-06	55.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_4	1122176.KB903609_gene5274	5.639e-213	673.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1IPH5@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
HKD3_k127_3891981_29	1122176.KB903598_gene4739	2.122e-79	282.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_12	760192.Halhy_4527	1.686e-142	463.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1IPSC@117747|Sphingobacteriia	976|Bacteroidetes	S	DNA mismatch repair protein MutT	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HKD3_k127_3891981_39	248742.XP_005647507.1	1.119e-58	215.0	KOG1610@1|root,KOG1610@2759|Eukaryota,388MC@33090|Viridiplantae,34P25@3041|Chlorophyta	3041|Chlorophyta	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_3891981_47	760192.Halhy_4731	1.165e-45	168.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1ISQ9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HKD3_k127_3891981_2	1122176.KB903531_gene3076	2.813e-238	760.0	COG3291@1|root,COG3291@2|Bacteria,4NICC@976|Bacteroidetes,1IXKI@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_3891981_50	153721.MYP_2329	4.415e-37	162.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,47QQB@768503|Cytophagia	976|Bacteroidetes	J	Telomere recombination	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
HKD3_k127_3891981_21	760192.Halhy_4727	1.227e-98	344.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1IP8V@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HKD3_k127_3891981_0	760192.Halhy_6202	0.0	1127.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IV0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
HKD3_k127_3891981_52	1121904.ARBP01000005_gene4869	1.757e-33	136.0	2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,47XNP@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
HKD3_k127_3891981_1	1122176.KB903543_gene651	4.913e-239	751.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IPA2@117747|Sphingobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
HKD3_k127_3891981_18	1227739.Hsw_1411	7.099e-103	341.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
HKD3_k127_3891981_49	760192.Halhy_0282	6.624e-40	152.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,1ISBI@117747|Sphingobacteriia	976|Bacteroidetes	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
HKD3_k127_3891981_16	1122176.KB903619_gene5428	1.964e-107	361.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
HKD3_k127_3891981_42	760192.Halhy_6385	1.165e-49	190.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
HKD3_k127_3891981_11	1122176.KB903598_gene4650	4.618e-148	487.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
HKD3_k127_3891981_31	760192.Halhy_6387	1.202e-75	262.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1IRI4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
HKD3_k127_3891981_23	1122176.KB903598_gene4653	2.377e-95	323.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1IQ87@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1131 ABC-type multidrug transport system ATPase component	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_3891981_28	1189612.A33Q_2943	1.263e-81	279.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD3_k127_3891981_35	1122179.KB890426_gene3973	8.562e-66	239.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1IPMS@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
HKD3_k127_3891981_13	1120966.AUBU01000010_gene2766	3.614e-128	430.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,47JEX@768503|Cytophagia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_3891981_48	1004149.AFOE01000009_gene2094	5.271e-44	171.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
HKD3_k127_3891981_20	760192.Halhy_1966	3.918e-101	346.0	COG1215@1|root,COG1215@2|Bacteria,4NFI8@976|Bacteroidetes,1ISNS@117747|Sphingobacteriia	976|Bacteroidetes	M	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
HKD3_k127_3891981_37	1122176.KB903619_gene5392	1.257e-63	235.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_14	760192.Halhy_5608	4.079e-119	396.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,1J0IU@117747|Sphingobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HKD3_k127_3891981_17	1122176.KB903619_gene5394	4.676e-104	344.0	COG0457@1|root,COG4221@1|root,COG0457@2|Bacteria,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_3891981_3	313606.M23134_03152	2.609e-222	706.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
HKD3_k127_3891981_24	760192.Halhy_4836	6.029e-95	321.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5I@976|Bacteroidetes,1IW0C@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
HKD3_k127_3891981_27	760192.Halhy_5145	5.002e-82	281.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1INKY@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.155,4.2.1.17	ko:K01715,ko:K20036	ko00650,ko00920,ko01200,map00650,map00920,map01200	-	R03026,R10936	RC00004,RC00831,RC03306,RC03307	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD3_k127_3891981_61	1122971.BAME01000098_gene5797	1.793e-20	96.0	2E37T@1|root,32Y7G@2|Bacteria,4NUTJ@976|Bacteroidetes,2FURK@200643|Bacteroidia,22YUZ@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
HKD3_k127_3891981_57	1229276.DI53_2054	7.722e-26	113.0	COG4640@1|root,COG4640@2|Bacteria,4NT0H@976|Bacteroidetes	976|Bacteroidetes	S	Interferon-induced transmembrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CD225,DUF4339
HKD3_k127_3891981_19	760192.Halhy_5360	2.462e-101	334.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1IQ54@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HKD3_k127_3891981_38	1122176.KB903576_gene4950	3.465e-62	229.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IT0Z@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
HKD3_k127_3891981_6	471854.Dfer_3741	1.448e-211	667.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_3891981_22	1122176.KB903531_gene3139	1.698e-95	315.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1ISGF@117747|Sphingobacteriia	976|Bacteroidetes	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
HKD3_k127_3891981_36	649349.Lbys_1435	5.905e-65	239.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
HKD3_k127_3891981_25	1122176.KB903544_gene747	1.416e-89	310.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1J0HU@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD3_k127_3891981_30	1122176.KB903547_gene1057	3.562e-78	285.0	COG3210@1|root,COG3591@1|root,COG3210@2|Bacteria,COG3591@2|Bacteria,4NG2K@976|Bacteroidetes	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_33	301.JNHE01000030_gene631	9.798e-68	232.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria,1YG66@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD3_k127_3891981_70	797302.Halru_0482	0.0007626	51.0	COG1404@1|root,arCOG10597@1|root,arCOG00702@2157|Archaea,arCOG10597@2157|Archaea,2XSZR@28890|Euryarchaeota,23U34@183963|Halobacteria	183963|Halobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
HKD3_k127_3891981_63	1313301.AUGC01000001_gene1815	4.912e-15	80.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes	976|Bacteroidetes	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_3891981_32	1237149.C900_03193	2.039e-73	258.0	COG2017@1|root,COG2017@2|Bacteria,4NE32@976|Bacteroidetes,47KZH@768503|Cytophagia	976|Bacteroidetes	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_69	1123392.AQWL01000011_gene2239	0.0005673	46.0	COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,2VVME@28216|Betaproteobacteria,1KSZV@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
HKD3_k127_3891981_58	1439940.BAY1663_04380	4.717e-23	106.0	COG2867@1|root,COG2867@2|Bacteria,1RM5K@1224|Proteobacteria,1S7NY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
HKD3_k127_3891981_68	760192.Halhy_0090	0.0004093	49.0	2BZC9@1|root,32R4S@2|Bacteria,4NQX4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_43	1122176.KB903531_gene2814	9.462e-49	190.0	COG0515@1|root,COG0515@2|Bacteria,4PKQ1@976|Bacteroidetes,1IYIR@117747|Sphingobacteriia	976|Bacteroidetes	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
HKD3_k127_3891981_9	984262.SGRA_1560	3.22e-164	538.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD3_k127_3891981_7	1122176.KB903576_gene4976	6.871e-204	686.0	COG0210@1|root,COG1112@1|root,COG1391@1|root,COG0210@2|Bacteria,COG1112@2|Bacteria,COG1391@2|Bacteria,4NGDS@976|Bacteroidetes,1IWRJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Superfamily I DNA and RNA	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_11,AAA_12,PDDEXK_1
HKD3_k127_3891981_34	643867.Ftrac_1715	1.369e-66	258.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,47PJM@768503|Cytophagia	976|Bacteroidetes	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
HKD3_k127_3891981_65	448385.sce2834	6.071e-07	61.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
HKD3_k127_3891981_59	1122176.KB903560_gene3539	1.062e-21	104.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,1ITHM@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_15	1122176.KB903540_gene40	5.76e-109	371.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1IPW4@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_3891981_26	1122176.KB903539_gene1336	4.766e-83	295.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IQVH@117747|Sphingobacteriia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
HKD3_k127_3891981_54	1408473.JHXO01000010_gene3584	7.095e-33	132.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,2G2BE@200643|Bacteroidia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
HKD3_k127_3891981_51	471870.BACINT_04260	7.985e-36	137.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,2FTXU@200643|Bacteroidia,4ARA7@815|Bacteroidaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD3_k127_3891981_8	1279009.ADICEAN_03476	2.978e-180	586.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47JW1@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
HKD3_k127_3891981_41	1185876.BN8_03734	1.7e-52	195.0	28IIU@1|root,2Z8JV@2|Bacteria,4NEFH@976|Bacteroidetes,47JU3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_46	313606.M23134_00471	2.285e-46	175.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
HKD3_k127_3891981_60	984262.SGRA_0459	2.683e-21	105.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3891981_5	760192.Halhy_6505	4.557e-212	679.0	COG0196@1|root,COG1216@1|root,COG0196@2|Bacteria,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1IP9Q@117747|Sphingobacteriia	976|Bacteroidetes	H	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HKD3_k127_3891981_44	1122176.KB903619_gene5437	2.205e-48	183.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,1IQTT@117747|Sphingobacteriia	976|Bacteroidetes	J	Pseudouridine synthase	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HKD3_k127_3891981_10	1122176.KB903537_gene1630	1.148e-149	488.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1IRWG@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
HKD3_k127_3891981_53	316067.Geob_0611	2.539e-33	134.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HKD3_k127_3891981_45	913325.N799_00750	9.902e-47	177.0	COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,1S2UY@1236|Gammaproteobacteria,1X43K@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_3921986_2	760192.Halhy_2029	9.735e-51	186.0	COG1876@1|root,COG1876@2|Bacteria,4NFA4@976|Bacteroidetes	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	-	-	-	-	-	-	-	-	-	-	VanY
HKD3_k127_3921986_4	1107311.Q767_05430	4.667e-39	152.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes,1I2UD@117743|Flavobacteriia,2NX08@237|Flavobacterium	976|Bacteroidetes	Q	Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
HKD3_k127_3921986_0	1122226.AUHX01000003_gene86	3.513e-170	537.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,1HXY6@117743|Flavobacteriia	976|Bacteroidetes	Q	With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HKD3_k127_3921986_3	1122176.KB903532_gene2700	6.451e-46	172.0	COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,1IYNI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
HKD3_k127_3921986_1	760192.Halhy_3786	1.045e-108	365.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1IWHK@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD3_k127_3921986_5	46234.ANA_C10313	0.000146	48.0	COG2361@1|root,COG2361@2|Bacteria,1G7TP@1117|Cyanobacteria,1HNW6@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
HKD3_k127_3960636_1	661478.OP10G_1178	8.549e-59	221.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
HKD3_k127_3960636_3	1121904.ARBP01000009_gene4366	2.324e-07	62.0	2CKSR@1|root,30RNP@2|Bacteria,4PB67@976|Bacteroidetes,47VAI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3960636_0	1121875.KB907549_gene1741	2.175e-190	605.0	COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,1HYNX@117743|Flavobacteriia	976|Bacteroidetes	S	RNA 2',3'-cyclic phosphate--5'-hydroxyl ligase	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
HKD3_k127_3960636_2	1286171.EAL2_c15250	1.806e-29	122.0	COG1371@1|root,COG1371@2|Bacteria,1VX66@1239|Firmicutes,252E3@186801|Clostridia	186801|Clostridia	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
HKD3_k127_4026615_0	401526.TcarDRAFT_2406	5.024e-87	297.0	COG3804@1|root,COG3804@2|Bacteria,1TRNF@1239|Firmicutes,4H7KW@909932|Negativicutes	909932|Negativicutes	C	Dihydrodipicolinate reductase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DapB_N
HKD3_k127_4026615_2	1313301.AUGC01000001_gene1701	1.369e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
HKD3_k127_4026615_1	649638.Trad_0043	9.388e-87	299.0	COG1230@1|root,COG2608@1|root,COG1230@2|Bacteria,COG2608@2|Bacteria,1WMIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,HMA
HKD3_k127_4037195_1	471854.Dfer_2459	1.016e-142	455.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,47KGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
HKD3_k127_4037195_0	1353531.AZNX01000005_gene3327	1.296e-174	557.0	COG4287@1|root,COG4287@2|Bacteria,1NP5V@1224|Proteobacteria	1224|Proteobacteria	O	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
HKD3_k127_4037195_2	1123242.JH636435_gene826	1.656e-66	228.0	COG0129@1|root,COG0129@2|Bacteria,2IWXV@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HKD3_k127_4084510_12	1239962.C943_04397	8.86e-06	48.0	2DQ9P@1|root,335HG@2|Bacteria,4NWBH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4084510_9	1122132.AQYH01000007_gene1986	7.993e-22	103.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria,4BMT3@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD3_k127_4084510_5	1178825.ALIH01000019_gene1232	9.621e-47	173.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes,1I4AH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
HKD3_k127_4084510_1	1230476.C207_02861	3.022e-109	369.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,3JQN6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HAMP
HKD3_k127_4084510_13	1173264.KI913949_gene3816	6.445e-05	51.0	2DYJH@1|root,34A3F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4084510_8	1434325.AZQN01000003_gene1923	6.759e-24	104.0	29WP1@1|root,30I9X@2|Bacteria,4NXPZ@976|Bacteroidetes,47SR6@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
HKD3_k127_4084510_11	1469557.JSWF01000044_gene597	3.049e-16	85.0	2AK8E@1|root,31AYP@2|Bacteria,4NRJ0@976|Bacteroidetes,1I39K@117743|Flavobacteriia	976|Bacteroidetes	S	NTPase	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_1
HKD3_k127_4084510_3	1123037.AUDE01000011_gene978	2.486e-59	218.0	28MR9@1|root,2ZAZY@2|Bacteria,4NHMN@976|Bacteroidetes,1I0R6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4084510_2	1122176.KB903561_gene3589	7.795e-63	226.0	COG2010@1|root,COG2010@2|Bacteria,4PEWN@976|Bacteroidetes,1IXW6@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HKD3_k127_4084510_7	1122176.KB903565_gene3340	1.782e-24	106.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HKD3_k127_4084510_10	485918.Cpin_6395	4.779e-17	86.0	2E3Q9@1|root,32YN7@2|Bacteria,4NWH3@976|Bacteroidetes	976|Bacteroidetes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
HKD3_k127_4084510_4	1122176.KB903561_gene3592	4.331e-57	204.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,1IY6E@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Lipid polyisoprenoid-binding, YceI-like	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_4084510_0	1122176.KB903561_gene3593	8.639e-111	366.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IXJN@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4096999_8	760192.Halhy_1999	1.246e-07	53.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD3_k127_4096999_2	1279009.ADICEAN_03634	7.436e-87	299.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47M8M@768503|Cytophagia	976|Bacteroidetes	K	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_4096999_4	1123277.KB893173_gene1724	2.122e-62	229.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47NKH@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_4096999_3	1123277.KB893173_gene1725	1.495e-82	286.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,47PTG@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
HKD3_k127_4096999_1	1122176.KB903546_gene988	2.823e-247	773.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes	976|Bacteroidetes	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD3_k127_4096999_5	1229276.DI53_2887	1.073e-53	200.0	2E6H2@1|root,33149@2|Bacteria,4P13M@976|Bacteroidetes,1IW07@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4096999_0	760192.Halhy_3337	1.151e-285	896.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1INSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HKD3_k127_4096999_6	359.CN09_33865	3.272e-35	151.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
HKD3_k127_4104928_7	760192.Halhy_1448	1.542e-70	250.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
HKD3_k127_4104928_9	760192.Halhy_1449	6.992e-59	213.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1ISRG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4104928_2	1122176.KB903541_gene247	1.324e-196	620.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1IP8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD3_k127_4104928_13	1122179.KB890469_gene463	1.297e-51	200.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C,DUF4150,PorP_SprF
HKD3_k127_4104928_6	1313301.AUGC01000004_gene2420	7.119e-85	289.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
HKD3_k127_4104928_18	1124780.ANNU01000045_gene2317	1.687e-17	85.0	2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,47RX3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4104928_17	760192.Halhy_3854	1.128e-17	94.0	COG3637@1|root,COG3637@2|Bacteria,4NYY3@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_4104928_12	760192.Halhy_3855	2.331e-53	204.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1IQTS@117747|Sphingobacteriia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
HKD3_k127_4104928_3	1122176.KB903598_gene4588	6.747e-139	457.0	COG1108@1|root,COG1108@2|Bacteria,4NH3D@976|Bacteroidetes,1IXC3@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC 3 transport family	mntD	-	-	ko:K11708,ko:K11709	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
HKD3_k127_4104928_15	760192.Halhy_2389	5.654e-35	138.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1ISV5@117747|Sphingobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD3_k127_4104928_0	485918.Cpin_6915	3.624e-248	785.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HKD3_k127_4104928_5	1122621.ATZA01000018_gene3894	5.422e-107	359.0	COG1052@1|root,COG1052@2|Bacteria,4PKE3@976|Bacteroidetes,1INZ9@117747|Sphingobacteriia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_4104928_8	1122176.KB903551_gene4229	1.293e-67	237.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1IP1V@117747|Sphingobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
HKD3_k127_4104928_16	1122176.KB903551_gene4228	4.257e-29	119.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1IUIV@117747|Sphingobacteriia	976|Bacteroidetes	S	Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
HKD3_k127_4104928_14	760192.Halhy_3993	6.345e-48	177.0	COG1225@1|root,COG1225@2|Bacteria,4NMGU@976|Bacteroidetes,1IS08@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD3_k127_4104928_10	1122176.KB903551_gene4226	6.992e-57	212.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1IP6X@117747|Sphingobacteriia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_4104928_11	1089547.KB913013_gene3596	1.405e-56	204.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
HKD3_k127_4104928_4	1122621.ATZA01000001_gene2015	9.294e-114	378.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD3_k127_4104928_1	1313421.JHBV01000038_gene2813	1.176e-221	697.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1J0XB@117747|Sphingobacteriia	976|Bacteroidetes	I	methylmalonyl-CoA mutase N-terminal domain	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
HKD3_k127_4115747_3	760192.Halhy_3077	1.414e-62	228.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_4115747_1	1122176.KB903544_gene726	4.095e-136	440.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
HKD3_k127_4115747_2	1122176.KB903537_gene1646	1.956e-93	341.0	COG1404@1|root,COG3209@1|root,COG3227@1|root,COG3292@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3227@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	B_lectin,CHB_HEX_C_1,DUF5011,LRR_5,PPC,Peptidase_S8,Reg_prop,Reprolysin_5
HKD3_k127_4115747_0	1237149.C900_03228	5.06e-234	732.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,47JBG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD3_k127_4145426_2	1237149.C900_03398	8.819e-41	166.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_4145426_0	1121904.ARBP01000015_gene198	1.083e-253	801.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,47JB3@768503|Cytophagia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD3_k127_4145426_1	1122176.KB903532_gene2631	1.482e-128	433.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1IQGK@117747|Sphingobacteriia	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
HKD3_k127_4145426_3	1123278.KB893569_gene2314	8.458e-24	104.0	2ET4W@1|root,33KNZ@2|Bacteria,4P5X3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4145426_4	471854.Dfer_1121	2.007e-10	70.0	2EKHJ@1|root,33E7I@2|Bacteria,4P6IY@976|Bacteroidetes,47WYG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4148627_0	760192.Halhy_1845	2.239e-223	698.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_4148627_1	984262.SGRA_3401	2.582e-77	275.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
HKD3_k127_4148627_2	1122176.KB903557_gene4035	1.398e-52	201.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
HKD3_k127_4148627_3	1122176.KB903557_gene4034	1.203e-15	78.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1IQJK@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HKD3_k127_4175747_24	760192.Halhy_5963	8.16e-22	102.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1ISWU@117747|Sphingobacteriia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HKD3_k127_4175747_22	1313421.JHBV01000040_gene2591	5.32e-33	140.0	298K1@1|root,3122S@2|Bacteria,4PGXN@976|Bacteroidetes,1IUN3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4175747_5	1122176.KB903534_gene2206	1.394e-179	572.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD3_k127_4175747_2	1406840.Q763_14780	4.36e-285	893.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia,2NT1D@237|Flavobacterium	976|Bacteroidetes	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD3_k127_4175747_1	1122605.KB893638_gene3456	0.0	1030.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IQ0B@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_4175747_19	272559.BF9343_3752	2.925e-60	214.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,2FQV3@200643|Bacteroidia,4AKJ7@815|Bacteroidaceae	976|Bacteroidetes	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_4175747_15	761193.Runsl_4194	1.008e-83	287.0	COG0135@1|root,COG0135@2|Bacteria,4NK5D@976|Bacteroidetes,47NUD@768503|Cytophagia	976|Bacteroidetes	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HKD3_k127_4175747_20	471854.Dfer_2254	3.68e-56	211.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_4175747_17	1123248.KB893348_gene324	3.729e-77	271.0	COG2972@1|root,COG2972@2|Bacteria,4NN11@976|Bacteroidetes,1IXVB@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_4175747_12	1123248.KB893348_gene325	6.63e-108	355.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1IX5E@117747|Sphingobacteriia	976|Bacteroidetes	K	Signal transduction response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_4175747_8	1150399.AQYK01000001_gene1288	7.745e-162	541.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FN63@85023|Microbacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,NB-ARC,TPR_12
HKD3_k127_4175747_16	1121859.KB890755_gene1269	1.218e-83	297.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,47JKK@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_4175747_7	1042376.AFPK01000044_gene2658	1.386e-163	526.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia,406ZC@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
HKD3_k127_4175747_3	1042376.AFPK01000044_gene2657	2.293e-183	589.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia,406XH@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
HKD3_k127_4175747_13	266748.HY04_02940	2.699e-107	356.0	COG1397@1|root,COG1397@2|Bacteria,4NF7H@976|Bacteroidetes,1HXII@117743|Flavobacteriia,3ZNTV@59732|Chryseobacterium	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HKD3_k127_4175747_9	1121930.AQXG01000001_gene1293	1.003e-141	464.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1IQCB@117747|Sphingobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HKD3_k127_4175747_6	760192.Halhy_4131	1.356e-169	542.0	COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1IP6Q@117747|Sphingobacteriia	976|Bacteroidetes	G	glucose-1-phosphate adenylyltransferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD3_k127_4175747_25	1239415.CM001837_gene2208	2.683e-15	87.0	COG0589@1|root,COG0589@2|Bacteria,4NGD6@976|Bacteroidetes,1HYDX@117743|Flavobacteriia,37DXB@326319|Dokdonia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_4175747_4	760192.Halhy_6156	4.457e-181	585.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1IQAZ@117747|Sphingobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
HKD3_k127_4175747_11	760192.Halhy_0933	8.672e-113	374.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD3_k127_4175747_21	760192.Halhy_0856	4.376e-34	138.0	2AF9A@1|root,3158F@2|Bacteria,4PJGJ@976|Bacteroidetes,1IZIZ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4175747_10	760192.Halhy_0857	3.573e-120	396.0	COG1842@1|root,COG1842@2|Bacteria,4NIZP@976|Bacteroidetes,1IZFV@117747|Sphingobacteriia	976|Bacteroidetes	KT	Phage shock protein A	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4175747_0	760192.Halhy_5393	0.0	1101.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
HKD3_k127_4175747_23	321332.CYB_1547	3.886e-22	106.0	COG0659@1|root,COG0659@2|Bacteria,1GPES@1117|Cyanobacteria,1H323@1129|Synechococcus	1117|Cyanobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4175747_14	760192.Halhy_5064	9.484e-101	341.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1IPZM@117747|Sphingobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HKD3_k127_4175747_18	1122176.KB903531_gene3000	3.644e-70	241.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1IP3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
HKD3_k127_4178814_0	388413.ALPR1_02210	4.155e-321	1014.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
HKD3_k127_4178814_3	1189619.pgond44_14048	1.671e-117	389.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia	976|Bacteroidetes	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
HKD3_k127_4178814_2	1137281.D778_00504	4.101e-121	397.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
HKD3_k127_4178814_4	925409.KI911562_gene2743	3.648e-50	182.0	COG0745@1|root,COG0745@2|Bacteria,4NQ69@976|Bacteroidetes,1ISWK@117747|Sphingobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HKD3_k127_4178814_1	1121875.KB907550_gene641	9.193e-141	458.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1HZ1W@117743|Flavobacteriia	976|Bacteroidetes	T	Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
HKD3_k127_4230726_2	1408473.JHXO01000005_gene1864	3.117e-37	147.0	2919D@1|root,2ZNWG@2|Bacteria,4NMU5@976|Bacteroidetes,2FW6F@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4230726_1	313603.FB2170_14828	1.591e-46	182.0	28PU4@1|root,2ZCF6@2|Bacteria,4NTXA@976|Bacteroidetes,1I497@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4230726_0	313603.FB2170_14833	5.346e-102	341.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PG6S@252356|Maribacter	976|Bacteroidetes	O	Cytochrome C assembly protein	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
HKD3_k127_4242348_9	1122176.KB903555_gene3780	1.146e-67	252.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1IR9Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
HKD3_k127_4242348_15	760192.Halhy_2698	1.013e-25	119.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1ISXE@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
HKD3_k127_4242348_11	760192.Halhy_2697	2.488e-59	218.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1IR1C@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
HKD3_k127_4242348_1	760192.Halhy_0330	4.327e-117	382.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HKD3_k127_4242348_12	760192.Halhy_0331	1.21e-57	206.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,1IRXT@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD3_k127_4242348_10	760192.Halhy_0332	3.927e-61	216.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD3_k127_4242348_8	760192.Halhy_0333	1.604e-72	253.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,1ISCX@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HKD3_k127_4242348_13	760192.Halhy_0335	4.603e-46	179.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,1IRT8@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD3_k127_4242348_6	760192.Halhy_0336	6.729e-91	319.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IPR2@117747|Sphingobacteriia	976|Bacteroidetes	NU	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
HKD3_k127_4242348_5	760192.Halhy_2696	1.782e-92	314.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1IP6P@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
HKD3_k127_4242348_14	485918.Cpin_0431	1.243e-31	138.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1ISTW@117747|Sphingobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4242348_4	1122176.KB903555_gene3786	1.396e-104	347.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1IR6K@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HKD3_k127_4242348_0	760192.Halhy_2693	2.351e-148	475.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD3_k127_4242348_2	1122176.KB903548_gene1215	5.899e-116	377.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
HKD3_k127_4242348_7	1122176.KB903545_gene821	1.52e-85	309.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1IQZP@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
HKD3_k127_4242348_3	1122176.KB903540_gene25	2.95e-107	357.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_4242348_16	926562.Oweho_0543	3.839e-21	93.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia,2PBN1@246874|Cryomorphaceae	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HNOBA,Reg_prop,Response_reg,TPR_12,Y_Y_Y
HKD3_k127_4250948_1	760192.Halhy_3815	1.216e-261	816.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1IP50@117747|Sphingobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HKD3_k127_4250948_4	867902.Ornrh_1425	8.168e-96	321.0	COG4783@1|root,COG4783@2|Bacteria,4NEF9@976|Bacteroidetes,1HZ36@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD3_k127_4250948_7	1121481.AUAS01000011_gene5029	1.482e-50	183.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,47PQ5@768503|Cytophagia	976|Bacteroidetes	H	PFAM 6-pyruvoyl tetrahydropterin synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD3_k127_4250948_6	1406840.Q763_13855	6.336e-59	223.0	COG0526@1|root,COG0526@2|Bacteria,4P2YC@976|Bacteroidetes,1I8S9@117743|Flavobacteriia,2NTRQ@237|Flavobacterium	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
HKD3_k127_4250948_9	643867.Ftrac_1376	2.538e-39	156.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,47WZW@768503|Cytophagia	976|Bacteroidetes	S	Excinuclease ABC subunit B	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
HKD3_k127_4250948_5	1237149.C900_02648	4.943e-84	290.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,47Q1V@768503|Cytophagia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_4250948_2	760192.Halhy_3260	1.502e-107	355.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1IQEQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HKD3_k127_4250948_0	760192.Halhy_3259	1.238e-298	921.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD3_k127_4250948_8	1122176.KB903565_gene3386	4.565e-48	178.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1ISSR@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HKD3_k127_4250948_10	1144313.PMI10_02598	5.128e-35	139.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia,2NW10@237|Flavobacterium	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HKD3_k127_4250948_11	714943.Mucpa_4028	2.532e-14	84.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1ITY0@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD3_k127_4250948_3	760192.Halhy_3255	1.346e-102	340.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HKD3_k127_4255782_1	504487.JCM19302_2833	2.071e-62	225.0	COG0296@1|root,COG0296@2|Bacteria,4NJ7Z@976|Bacteroidetes,1HZ6E@117743|Flavobacteriia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
HKD3_k127_4255782_2	1121931.AUHG01000020_gene3174	5.49e-57	211.0	2DBKE@1|root,2Z9SW@2|Bacteria,4NRWN@976|Bacteroidetes,1I012@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
HKD3_k127_4255782_0	984262.SGRA_1497	0.0	1394.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HKD3_k127_4259114_2	1121481.AUAS01000004_gene1437	3.065e-70	253.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47PQN@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_4259114_0	1121898.Q766_16495	2.569e-138	451.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,2NSN5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD3_k127_4259114_3	1121859.KB890738_gene3346	5.226e-43	164.0	COG1733@1|root,COG1733@2|Bacteria,4NPUK@976|Bacteroidetes,47SIJ@768503|Cytophagia	976|Bacteroidetes	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD3_k127_4259114_1	468059.AUHA01000004_gene2327	2.678e-119	387.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,1IWMM@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
HKD3_k127_4276209_3	1313421.JHBV01000042_gene3241	9.31e-05	46.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1J0BJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_4276209_0	984262.SGRA_1374	1.446e-42	160.0	COG0432@1|root,COG0432@2|Bacteria,4NNMN@976|Bacteroidetes,1ISBQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
HKD3_k127_4276209_2	1120968.AUBX01000012_gene2873	2.156e-14	83.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_4276209_1	927658.AJUM01000037_gene2050	2.567e-34	139.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,2FMXN@200643|Bacteroidia,3XK5K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	yihX	GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.10,3.1.3.104	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	M00125	R00947,R07280	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
HKD3_k127_429610_3	1168034.FH5T_05410	5.323e-59	213.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,2FMP9@200643|Bacteroidia	976|Bacteroidetes	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HKD3_k127_429610_2	1123008.KB905694_gene1672	2.165e-71	251.0	COG3341@1|root,COG3341@2|Bacteria,4PKFF@976|Bacteroidetes,2G3F9@200643|Bacteroidia,2322B@171551|Porphyromonadaceae	976|Bacteroidetes	L	Caulimovirus viroplasmin	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
HKD3_k127_429610_1	1122179.KB890416_gene2714	1.001e-73	252.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1IRF3@117747|Sphingobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD3_k127_429610_4	929562.Emtol_1652	5.189e-29	122.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,47QCM@768503|Cytophagia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD3_k127_429610_0	760192.Halhy_3866	1.45e-126	439.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Beta_helix,Calx-beta,DUF4347,SLH,VCBS
HKD3_k127_438875_0	1122194.AUHU01000005_gene963	0.0	1352.0	COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1T315@1236|Gammaproteobacteria,46AA9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,Pkinase
HKD3_k127_438875_8	1173264.KI913949_gene2269	2.253e-52	214.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
HKD3_k127_438875_4	865937.Gilli_0822	1.593e-125	409.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia	976|Bacteroidetes	HJ	Ribosomal protein S6 modification	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
HKD3_k127_438875_5	865937.Gilli_0820	3.453e-110	373.0	COG3572@1|root,COG3572@2|Bacteria	2|Bacteria	H	ergothioneine biosynthetic process	egtA	GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3704c	GCS2
HKD3_k127_438875_2	865937.Gilli_0818	2.001e-196	623.0	2DUAW@1|root,33PQT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_438875_1	865937.Gilli_0826	3.922e-204	662.0	COG3511@1|root,COG3511@2|Bacteria,4NNZX@976|Bacteroidetes,1I5X5@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
HKD3_k127_438875_9	616991.JPOO01000001_gene4614	1.409e-44	169.0	2AY99@1|root,31QBJ@2|Bacteria,4NNSA@976|Bacteroidetes,1I2AG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
HKD3_k127_438875_12	929703.KE386491_gene3791	2.889e-07	54.0	2DF4C@1|root,2ZQFT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_438875_6	929556.Solca_0150	2.344e-75	263.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,4NHWS@976|Bacteroidetes,1IS66@117747|Sphingobacteriia	976|Bacteroidetes	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
HKD3_k127_438875_7	313596.RB2501_03645	6.833e-58	207.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1I33C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_438875_10	614083.AWQR01000009_gene590	4.124e-19	97.0	28ME7@1|root,2ZARX@2|Bacteria,1R90X@1224|Proteobacteria,2VNB6@28216|Betaproteobacteria,4AA7V@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_438875_11	1122176.KB903552_gene3706	7.676e-13	70.0	COG1522@1|root,COG1522@2|Bacteria,4NPYG@976|Bacteroidetes	976|Bacteroidetes	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
HKD3_k127_439323_1	1122176.KB903550_gene4340	9.668e-79	273.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HKD3_k127_439323_4	1123057.P872_21260	4.427e-32	130.0	COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HKD3_k127_439323_3	1123057.P872_21265	7.083e-68	242.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47UNC@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_439323_0	929556.Solca_2233	3.723e-112	370.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
HKD3_k127_439323_2	866536.Belba_1302	1.892e-77	275.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HKD3_k127_4449733_3	760192.Halhy_4973	1.381e-54	193.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1IT1D@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
HKD3_k127_4449733_1	1237149.C900_00985	1.739e-63	226.0	COG0262@1|root,COG0262@2|Bacteria,4NM92@976|Bacteroidetes,47QQZ@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD3_k127_4449733_2	1227739.Hsw_2586	2.44e-57	205.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,47Q73@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_4449733_4	1454007.JAUG01000007_gene2184	2.686e-53	194.0	COG1670@1|root,COG1670@2|Bacteria,4NPHU@976|Bacteroidetes,1ITAI@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HKD3_k127_4449733_5	1313421.JHBV01000034_gene1693	1.247e-18	101.0	COG3227@1|root,COG3391@1|root,COG3227@2|Bacteria,COG3391@2|Bacteria,4P12F@976|Bacteroidetes	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4449733_0	595460.RRSWK_03305	7.29e-160	531.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	-
HKD3_k127_4451770_2	1120934.KB894432_gene6137	3.474e-41	162.0	2C73B@1|root,330Z7@2|Bacteria,2IIMQ@201174|Actinobacteria,4E6EA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
HKD3_k127_4451770_1	1121887.AUDK01000005_gene3033	8.59e-102	337.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia,2NUSC@237|Flavobacterium	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
HKD3_k127_4451770_3	1173024.KI912149_gene5790	2.237e-14	76.0	COG3224@1|root,COG3224@2|Bacteria,1GKNM@1117|Cyanobacteria,1JMGI@1189|Stigonemataceae	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4451770_0	643867.Ftrac_1520	1.565e-143	464.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,47JBV@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_451135_6	1178825.ALIH01000015_gene1867	2.911e-30	133.0	COG1361@1|root,COG2304@1|root,COG3209@1|root,COG3291@1|root,COG4935@1|root,COG5384@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5384@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_451135_1	1123277.KB893174_gene5927	2.637e-80	302.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_451135_2	1122605.KB893648_gene3650	8.411e-71	248.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_451135_5	690850.Desaf_2584	2.2e-34	144.0	COG0385@1|root,COG0385@2|Bacteria,1Q36S@1224|Proteobacteria,42WV7@68525|delta/epsilon subdivisions,2WSXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
HKD3_k127_451135_4	1121904.ARBP01000009_gene4379	2.075e-44	175.0	2DICZ@1|root,32UAY@2|Bacteria,4NU7D@976|Bacteroidetes,47SYM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_451135_3	1121904.ARBP01000009_gene4379	9.272e-49	183.0	2DICZ@1|root,32UAY@2|Bacteria,4NU7D@976|Bacteroidetes,47SYM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_451135_7	1120966.AUBU01000003_gene1408	6.145e-21	101.0	COG2928@1|root,COG2928@2|Bacteria,4NT13@976|Bacteroidetes,47VR6@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
HKD3_k127_451135_8	927658.AJUM01000042_gene1465	0.0001019	55.0	COG0308@1|root,COG4733@1|root,COG0308@2|Bacteria,COG4733@2|Bacteria,4NGTZ@976|Bacteroidetes,2FQE9@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
HKD3_k127_451135_0	1239962.C943_02025	2.226e-131	425.0	COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,47P83@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563,ko:K22318	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD3_k127_455969_1	1239962.C943_02087	2.543e-118	385.0	COG3832@1|root,COG3865@1|root,COG3832@2|Bacteria,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,47PVI@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
HKD3_k127_455969_3	317936.Nos7107_3526	2.038e-42	157.0	2AFVV@1|root,315YK@2|Bacteria,1GHAK@1117|Cyanobacteria,1HSK7@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_455969_2	531844.FIC_00885	4.194e-60	215.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I2AJ@117743|Flavobacteriia,406IN@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
HKD3_k127_455969_0	531844.FIC_00884	2.65e-174	556.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1HX0C@117743|Flavobacteriia,4063I@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
HKD3_k127_4646137_6	468059.AUHA01000007_gene2661	3.621e-47	178.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_4646137_2	1237149.C900_02167	2.828e-88	298.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
HKD3_k127_4646137_5	1121904.ARBP01000002_gene7147	2.074e-48	181.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
HKD3_k127_4646137_7	1048983.EL17_01610	4.189e-17	87.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
HKD3_k127_4646137_1	929713.NIASO_09280	3.841e-174	557.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
HKD3_k127_4646137_3	700598.Niako_1943	9.627e-76	268.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
HKD3_k127_4646137_9	485918.Cpin_0682	5.12e-10	64.0	COG2010@1|root,COG2010@2|Bacteria,4PJ6S@976|Bacteroidetes,1IZP1@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4646137_0	929713.NIASO_09295	0.0	1200.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
HKD3_k127_4646137_8	929556.Solca_1390	1.972e-11	66.0	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
HKD3_k127_4646137_4	485918.Cpin_0679	3.655e-64	228.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_4668953_1	471854.Dfer_1279	1.259e-108	356.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_4668953_0	471854.Dfer_1503	1.427e-120	408.0	COG1956@1|root,COG2972@1|root,COG3292@1|root,COG1956@2|Bacteria,COG2972@2|Bacteria,COG3292@2|Bacteria,4NHMQ@976|Bacteroidetes,47P3A@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_4840030_0	760192.Halhy_1366	2.904e-103	351.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_4840030_2	1408473.JHXO01000011_gene3147	1.256e-72	253.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,2FNI4@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD3_k127_4840030_3	1346330.M472_05615	5.51e-18	89.0	COG3063@1|root,COG3063@2|Bacteria,4PKQM@976|Bacteroidetes,1J0N6@117747|Sphingobacteriia	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HKD3_k127_4840030_1	1313421.JHBV01000041_gene3636	7.57e-85	287.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1IQTX@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD3_k127_4864427_3	925409.KI911562_gene1824	8.852e-11	65.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
HKD3_k127_4864427_1	1249975.JQLP01000005_gene887	1.891e-53	196.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,1I1TM@117743|Flavobacteriia,2P6PS@244698|Gillisia	976|Bacteroidetes	S	YceI-like domain	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_4864427_2	879243.Poras_1010	2.032e-51	192.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,2FNUW@200643|Bacteroidia,22VX2@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HKD3_k127_4864427_0	391596.PBAL39_09766	1.056e-160	519.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HKD3_k127_4865067_17	1122605.KB893627_gene2910	5.166e-05	50.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1ISX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
HKD3_k127_4865067_4	760192.Halhy_0146	6.365e-151	487.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
HKD3_k127_4865067_2	1122176.KB903562_gene3426	5.64e-217	683.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1IPSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD3_k127_4865067_3	1004149.AFOE01000059_gene303	4.588e-190	601.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1HZCP@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_4865067_10	1122176.KB903531_gene3025	6.237e-52	190.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS97@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HKD3_k127_4865067_12	1121481.AUAS01000018_gene403	2.07e-45	172.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,47P9D@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
HKD3_k127_4865067_13	700598.Niako_4567	1.723e-40	161.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,1IRVF@117747|Sphingobacteriia	976|Bacteroidetes	EG	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_4865067_9	926556.Echvi_0142	6.012e-71	244.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
HKD3_k127_4865067_6	760192.Halhy_5606	1.278e-130	432.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD3_k127_4865067_8	1122176.KB903609_gene5207	6.116e-85	291.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1ISHE@117747|Sphingobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HKD3_k127_4865067_1	1122176.KB903538_gene1482	5.549e-232	727.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1INX4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HKD3_k127_4865067_14	1122176.KB903538_gene1481	1.092e-38	162.0	COG0683@1|root,COG0683@2|Bacteria,4PMPE@976|Bacteroidetes,1ISIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
HKD3_k127_4865067_5	1121897.AUGO01000002_gene2105	1.171e-148	481.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia,2NSGC@237|Flavobacterium	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_4865067_0	1121875.KB907546_gene2658	6.536e-256	797.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HYE9@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD3_k127_4865067_15	1461580.CCAS010000038_gene3161	2.606e-07	61.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,1ZHDQ@1386|Bacillus	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
HKD3_k127_4865067_16	1122176.KB903531_gene2840	4.852e-05	56.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
HKD3_k127_4865067_11	760192.Halhy_4996	6.148e-50	206.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
HKD3_k127_4865067_7	1519464.HY22_00050	1.831e-90	308.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HKD3_k127_4877490_1	760192.Halhy_5694	2.599e-82	282.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1J0XQ@117747|Sphingobacteriia	976|Bacteroidetes	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4877490_0	760192.Halhy_5695	0.0	1179.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1IP08@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
HKD3_k127_4879961_3	118161.KB235922_gene5582	1.02e-50	184.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,3VMJH@52604|Pleurocapsales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
HKD3_k127_4879961_5	1116472.MGMO_8c00150	9.081e-32	128.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria,1XGMP@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4879961_0	1122176.KB903534_gene2082	0.0	1062.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes	976|Bacteroidetes	O	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
HKD3_k127_4879961_2	1123248.KB893348_gene253	5.286e-55	203.0	COG0115@1|root,COG0115@2|Bacteria,4PFUA@976|Bacteroidetes,1IS3V@117747|Sphingobacteriia	976|Bacteroidetes	EH	Amino-transferase class IV	-	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_4879961_1	1122176.KB903541_gene244	2.963e-259	829.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1IQ6P@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
HKD3_k127_4879961_6	926550.CLDAP_38400	1.016e-14	85.0	COG0297@1|root,COG0297@2|Bacteria,2GA6I@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase Family 4	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_4879961_4	671143.DAMO_0254	4.59e-37	149.0	COG2120@1|root,COG2120@2|Bacteria,2NQ6H@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,PIG-L
HKD3_k127_4884740_1	1120966.AUBU01000003_gene1299	5.658e-130	421.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,47MJG@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_4884740_2	760192.Halhy_1998	2.641e-64	228.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1IQ2V@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
HKD3_k127_4884740_0	1122176.KB903565_gene3307	1.423e-191	606.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD3_k127_4889870_2	938709.AUSH02000016_gene755	1.612e-105	347.0	COG3329@1|root,COG3329@2|Bacteria,4NIR4@976|Bacteroidetes	976|Bacteroidetes	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
HKD3_k127_4889870_3	1123057.P872_09120	2.68e-31	129.0	2EEMG@1|root,338FD@2|Bacteria,4NW27@976|Bacteroidetes,47T2U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4889870_1	938709.AUSH02000016_gene758	9.339e-109	359.0	2DBB9@1|root,2Z86U@2|Bacteria,4NI91@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4889870_4	929703.KE386491_gene941	2.707e-15	79.0	2EK9D@1|root,33DZP@2|Bacteria,4NXY8@976|Bacteroidetes,47T67@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4889870_0	1239962.C943_02343	1.403e-208	652.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,47KD2@768503|Cytophagia	976|Bacteroidetes	CE	Isocitrate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_4895324_13	1197477.IA57_02145	1.069e-81	280.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1I05P@117743|Flavobacteriia	976|Bacteroidetes	S	Phenylacetate-CoA oxygenase	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HKD3_k127_4895324_16	420324.KI911965_gene567	1.87e-45	169.0	COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2TRQW@28211|Alphaproteobacteria,1JV3T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaJ	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
HKD3_k127_4895324_7	760192.Halhy_0107	5.979e-129	422.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,1INTU@117747|Sphingobacteriia	976|Bacteroidetes	J	PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HKD3_k127_4895324_11	1356852.N008_07860	3.831e-96	322.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,47JJ9@768503|Cytophagia	976|Bacteroidetes	I	enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD3_k127_4895324_5	984262.SGRA_p0040	3.221e-130	429.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes	976|Bacteroidetes	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_4895324_20	700598.Niako_6202	1.254e-35	142.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1IYJ0@117747|Sphingobacteriia	976|Bacteroidetes	Q	Thioesterase superfamily	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
HKD3_k127_4895324_24	1122176.KB903543_gene624	7.214e-26	113.0	2E598@1|root,3301J@2|Bacteria,4NUX7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4895324_22	760192.Halhy_1777	1.2e-30	134.0	COG1765@1|root,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1ITTE@117747|Sphingobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	Fer4_19,OsmC
HKD3_k127_4895324_15	760192.Halhy_3536	1.283e-51	196.0	COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,1ISGD@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_4895324_29	485917.Phep_4231	1.116e-05	54.0	2A95J@1|root,30YA2@2|Bacteria,4NP9E@976|Bacteroidetes,1ITH5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4895324_25	1121889.AUDM01000004_gene2706	1.958e-24	116.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,1HYD6@117743|Flavobacteriia,2NV26@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4895324_0	313606.M23134_04190	5.601e-232	732.0	COG1132@1|root,COG1132@2|Bacteria,4NHI1@976|Bacteroidetes,47JJQ@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_4895324_21	485913.Krac_3036	9.136e-35	140.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudK	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0046872,GO:0052751	3.6.1.13	ko:K01515,ko:K12945	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iLF82_1304.LF82_1537,iNRG857_1313.NRG857_12310,iUTI89_1310.UTI89_C2793,ic_1306.c2994	NUDIX
HKD3_k127_4895324_18	398720.MED217_14420	1.036e-40	162.0	COG2353@1|root,COG2353@2|Bacteria,4NMFT@976|Bacteroidetes,1I1D2@117743|Flavobacteriia,2XIF4@283735|Leeuwenhoekiella	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_4895324_17	1122176.KB903543_gene619	3.39e-41	164.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,1IS5U@117747|Sphingobacteriia	976|Bacteroidetes	K	MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
HKD3_k127_4895324_3	1122176.KB903543_gene617	1.426e-174	554.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_4895324_10	760192.Halhy_3302	3.141e-97	330.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1IR7M@117747|Sphingobacteriia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD3_k127_4895324_9	1121875.KB907551_gene1069	6.936e-101	339.0	COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,1HYBV@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
HKD3_k127_4895324_8	1122176.KB903531_gene2961	6.79e-123	398.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_4895324_23	1250278.JQNQ01000001_gene1666	2.189e-30	130.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1I1FE@117743|Flavobacteriia	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
HKD3_k127_4895324_12	760192.Halhy_2745	9.381e-87	292.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1IRUN@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_4895324_2	1122176.KB903543_gene616	1.249e-179	576.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1IPV4@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HKD3_k127_4895324_28	1121904.ARBP01000002_gene7195	2.599e-11	66.0	2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4895324_19	760192.Halhy_3182	1.447e-36	145.0	COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_4895324_14	1122176.KB903534_gene2068	1.525e-56	204.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_4895324_4	1406840.Q763_13030	1.327e-141	464.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2NSUV@237|Flavobacterium	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
HKD3_k127_4895324_1	1122179.KB890425_gene3502	2.814e-200	644.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HKD3_k127_4895324_6	760192.Halhy_0625	3.617e-129	422.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD3_k127_4895324_27	880071.Fleli_0254	4.294e-15	84.0	2DPNX@1|root,332TS@2|Bacteria,4NR4X@976|Bacteroidetes,47VVP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4942763_2	1249997.JHZW01000002_gene196	3.045e-92	313.0	COG2367@1|root,COG2367@2|Bacteria,4NHT5@976|Bacteroidetes,1HWY4@117743|Flavobacteriia,2PIHX@252356|Maribacter	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HKD3_k127_4942763_0	1348583.ATLH01000013_gene2762	4.669e-160	538.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia,1FA5V@104264|Cellulophaga	976|Bacteroidetes	C	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
HKD3_k127_4942763_1	1250232.JQNJ01000001_gene1635	1.079e-131	426.0	COG2367@1|root,COG2367@2|Bacteria,4NHF9@976|Bacteroidetes,1HZHM@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
HKD3_k127_4981018_5	760192.Halhy_1233	1.532e-33	137.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_4981018_2	1123277.KB893178_gene2607	1.838e-149	492.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD3_k127_4981018_6	760192.Halhy_2522	6.143e-15	82.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1IU0K@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HKD3_k127_4981018_3	760192.Halhy_1599	2.006e-89	303.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1IQAN@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
HKD3_k127_4981018_4	1338011.BD94_2120	1.871e-58	210.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1HWU0@117743|Flavobacteriia,34QVV@308865|Elizabethkingia	976|Bacteroidetes	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD3_k127_4981018_1	1121930.AQXG01000003_gene2691	5.358e-163	534.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
HKD3_k127_4981018_0	1168034.FH5T_01730	2.086e-214	675.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD3_k127_4986697_0	1305737.JAFX01000001_gene547	5.564e-99	331.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47PIS@768503|Cytophagia	976|Bacteroidetes	M	Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
HKD3_k127_4986697_1	1189620.AJXL01000010_gene2548	5.655e-31	127.0	COG0782@1|root,COG0782@2|Bacteria,4PA35@976|Bacteroidetes,1IDS7@117743|Flavobacteriia,2NZ2R@237|Flavobacterium	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4991652_6	945713.IALB_0147	2.036e-08	63.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
HKD3_k127_4991652_3	760192.Halhy_2959	5.212e-70	241.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
HKD3_k127_4991652_1	984262.SGRA_0635	1.094e-149	483.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
HKD3_k127_4991652_0	391587.KAOT1_08258	5.039e-202	654.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_4991652_2	1313421.JHBV01000015_gene5760	2.852e-110	370.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,1IQNH@117747|Sphingobacteriia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
HKD3_k127_4991652_4	1237149.C900_02627	6.184e-28	119.0	2EDHQ@1|root,30K5G@2|Bacteria,4PC44@976|Bacteroidetes,47WSK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5006165_1	1121481.AUAS01000020_gene5234	2.116e-115	383.0	COG1073@1|root,COG1073@2|Bacteria,4PM54@976|Bacteroidetes,47Y7X@768503|Cytophagia	976|Bacteroidetes	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
HKD3_k127_5006165_3	1223410.KN050846_gene489	1.567e-54	209.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
HKD3_k127_5006165_7	290315.Clim_0508	1.354e-09	68.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,NlpE,YscW
HKD3_k127_5006165_6	509635.N824_26450	6.319e-38	162.0	COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,1IXHS@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_5006165_2	1121288.AULL01000007_gene1425	3.001e-79	272.0	COG0704@1|root,COG0704@2|Bacteria,4NNT5@976|Bacteroidetes,1I1UU@117743|Flavobacteriia	976|Bacteroidetes	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HKD3_k127_5006165_0	1237149.C900_04449	2.735e-117	385.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,47NU6@768503|Cytophagia	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HKD3_k127_5006165_4	1237149.C900_04448	3.772e-48	173.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,47KZ4@768503|Cytophagia	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD3_k127_5008301_1	929556.Solca_2271	1.292e-40	160.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1IQGQ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_5008301_0	760192.Halhy_2783	7.484e-293	907.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HKD3_k127_5008301_2	1122176.KB903548_gene1180	4.077e-32	132.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPM9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD3_k127_5018896_0	1122176.KB903538_gene1475	5.699e-87	294.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes,1IUAK@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
HKD3_k127_5018896_1	1122179.KB890435_gene930	4.294e-45	172.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1IS95@117747|Sphingobacteriia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
HKD3_k127_5018896_3	1122176.KB903538_gene1476	1.474e-21	105.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1ISTG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein, GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5018896_2	1313421.JHBV01000049_gene75	1.588e-44	166.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
HKD3_k127_5031170_4	1121012.AUKX01000011_gene2323	2.137e-28	118.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia,23GQS@178469|Arenibacter	976|Bacteroidetes	U	Sec-independent protein translocase protein (TatC)	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_5031170_3	880070.Cycma_1101	8.231e-40	152.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,47KG0@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_5031170_0	1122179.KB890491_gene4501	5.432e-231	748.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
HKD3_k127_5031170_2	1122179.KB890413_gene4874	2.729e-116	388.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
HKD3_k127_5031170_1	760192.Halhy_2715	4.47e-201	636.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1IPUW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD3_k127_5032857_0	760192.Halhy_3666	5.674e-152	487.0	COG1363@1|root,COG1363@2|Bacteria,4NIW2@976|Bacteroidetes,1J085@117747|Sphingobacteriia	976|Bacteroidetes	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD3_k127_5032857_3	760192.Halhy_3119	9.426e-26	112.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1ITUM@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
HKD3_k127_5032857_1	1122179.KB890413_gene4796	4.321e-129	427.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1IP0R@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_5032857_2	761193.Runsl_2267	1.498e-47	175.0	COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,47PSM@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
HKD3_k127_5032857_4	1123400.KB904765_gene1396	2.16e-25	122.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
HKD3_k127_5069542_1	755732.Fluta_3094	6.871e-19	88.0	2EHZ3@1|root,33BQJ@2|Bacteria,4NXH5@976|Bacteroidetes	976|Bacteroidetes	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1
HKD3_k127_5069542_0	929556.Solca_1727	5.203e-321	1008.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD3_k127_5074284_1	1122176.KB903550_gene4348	4.066e-84	289.0	COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,1IUVE@117747|Sphingobacteriia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
HKD3_k127_5074284_2	760192.Halhy_0368	1.355e-61	222.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
HKD3_k127_5074284_4	1121890.AUDO01000011_gene406	7.35e-51	194.0	2B2RR@1|root,2Z9ZD@2|Bacteria,4NKN4@976|Bacteroidetes,1I6DZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5074284_0	865937.Gilli_0101	2.555e-131	425.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia,2P6G4@244698|Gillisia	976|Bacteroidetes	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD3_k127_5074284_3	745718.JADT01000001_gene1977	4.838e-58	222.0	COG4676@1|root,COG4676@2|Bacteria,4NISW@976|Bacteroidetes,1I0BF@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0560
HKD3_k127_5075487_1	1122176.KB903532_gene2749	2.621e-215	691.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HKD3_k127_5075487_0	1122176.KB903542_gene307	2.032e-254	805.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1IP5W@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock protein Hsp90	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
HKD3_k127_5075487_2	760192.Halhy_5351	8.442e-149	490.0	COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5075487_3	760192.Halhy_3973	1.434e-35	139.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1IQB4@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
HKD3_k127_5081860_1	1122176.KB903549_gene1231	2.367e-53	213.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,1IQUD@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
HKD3_k127_5081860_0	946077.W5A_11801	3.641e-78	271.0	COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,1HX1K@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_5081860_2	1122176.KB903568_gene3477	2.19e-46	193.0	COG3210@1|root,COG4935@1|root,COG3210@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	avxIA	-	-	ko:K11016	ko03070,map03070	-	-	-	ko00000,ko00001,ko02042,ko02044	-	-	-	HemolysinCabind,PKD,P_proprotein,Peptidase_S8,Reprolysin_5
HKD3_k127_5116798_0	760192.Halhy_3400	4.671e-99	337.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1IPM6@117747|Sphingobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
HKD3_k127_5116798_1	1408433.JHXV01000032_gene1133	1.228e-74	270.0	COG1807@1|root,COG1807@2|Bacteria,4PG9X@976|Bacteroidetes,1IMRA@117743|Flavobacteriia,2PBNI@246874|Cryomorphaceae	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_5123041_3	688270.Celal_0488	2.984e-21	102.0	28IMM@1|root,2Z8N3@2|Bacteria,4NGS9@976|Bacteroidetes,1I05I@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5123041_1	1124780.ANNU01000023_gene3232	2.691e-151	493.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MR6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Alpha amylase, catalytic	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,BACON,DUF3459
HKD3_k127_5123041_0	1197477.IA57_07980	2.737e-163	523.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
HKD3_k127_5123041_2	246197.MXAN_0918	8.659e-143	459.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,431I4@68525|delta/epsilon subdivisions,2WW88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
HKD3_k127_5137736_6	1122176.KB903531_gene2848	5.843e-66	231.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HKD3_k127_5137736_1	1122176.KB903531_gene2847	6.397e-119	393.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IQAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_5137736_10	644281.MFS40622_0254	2.552e-10	72.0	arCOG02499@1|root,arCOG02499@2157|Archaea,2Y7Q6@28890|Euryarchaeota,23QW5@183939|Methanococci	183939|Methanococci	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_5137736_9	313603.FB2170_04095	1.473e-14	85.0	2EAVS@1|root,334X4@2|Bacteria,4NWJY@976|Bacteroidetes,1I6CS@117743|Flavobacteriia,2PGZF@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5137736_8	111105.HR09_08960	5.731e-22	104.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,22Y0T@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	yfiC	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
HKD3_k127_5137736_7	1122176.KB903609_gene5206	1.372e-28	117.0	2CZWI@1|root,32T79@2|Bacteria,4NSNW@976|Bacteroidetes	976|Bacteroidetes	S	COG NOG19094 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5137736_0	1122176.KB903619_gene5465	1.646e-186	590.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1IQNN@117747|Sphingobacteriia	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD3_k127_5137736_4	1122176.KB903554_gene3882	2.777e-84	287.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD3_k127_5137736_5	649349.Lbys_2372	2.131e-68	239.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,47KV5@768503|Cytophagia	976|Bacteroidetes	J	Pseudouridine synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD3_k127_5137736_2	760192.Halhy_0294	4.434e-116	376.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1IP8P@117747|Sphingobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HKD3_k127_5137736_3	1211813.CAPH01000003_gene1347	1.062e-93	329.0	COG1807@1|root,COG1807@2|Bacteria,4NEU7@976|Bacteroidetes,2G1V2@200643|Bacteroidia,22UW2@171550|Rikenellaceae	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_5179180_3	1124780.ANNU01000071_gene1029	1.02e-49	181.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,47KZ4@768503|Cytophagia	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD3_k127_5179180_0	468059.AUHA01000002_gene577	1.092e-132	429.0	COG0573@1|root,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,1IPVZ@117747|Sphingobacteriia	976|Bacteroidetes	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD3_k127_5179180_1	1124780.ANNU01000071_gene1027	5.864e-122	400.0	COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,47P5H@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
HKD3_k127_5179180_2	926560.KE387023_gene2062	2.321e-95	322.0	COG1073@1|root,COG1073@2|Bacteria,1WMDB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD3_k127_5187313_1	925409.KI911562_gene1331	3.059e-88	294.0	COG0262@1|root,COG0262@2|Bacteria,4NPM3@976|Bacteroidetes,1IT7M@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HKD3_k127_5187313_0	1122179.KB890425_gene3419	6.801e-310	961.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_5187313_2	391587.KAOT1_11712	9.577e-16	84.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
HKD3_k127_5214544_0	1123248.KB893386_gene1917	7.891e-147	470.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IR88@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD3_k127_5214544_2	763034.HMPREF9446_02973	2.337e-12	79.0	COG3187@1|root,COG3187@2|Bacteria,4NWRF@976|Bacteroidetes,2FNPG@200643|Bacteroidia,4AR39@815|Bacteroidaceae	976|Bacteroidetes	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5214544_1	1121007.AUML01000047_gene4036	1.415e-72	250.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1HY8Z@117743|Flavobacteriia,2YIXZ@290174|Aquimarina	976|Bacteroidetes	IQ	NAD(P)H-binding	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_5233367_3	1122176.KB903536_gene1829	8.727e-25	108.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	1.1.3.9,3.2.1.4	ko:K01179,ko:K01997,ko:K04618	ko00052,ko00500,ko01100,ko02010,ko02024,map00052,map00500,map01100,map02010,map02024	M00237	R01098,R06200,R11307,R11308	RC00194	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.4	GH5,GH9	-	CHU_C,DUF1929,F5_F8_type_C,Glyco_hydro_64,PKD,SprB
HKD3_k127_5233367_1	485918.Cpin_5439	2.516e-77	262.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1IQEI@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
HKD3_k127_5233367_2	1341181.FLJC2902T_14510	1.23e-72	254.0	COG3637@1|root,COG3637@2|Bacteria,4NPV9@976|Bacteroidetes,1I47X@117743|Flavobacteriia,2NSX3@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_5233367_0	1239962.C943_00981	2.743e-131	428.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5256465_8	760192.Halhy_3015	1.68e-58	214.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1J0BJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_5256465_2	984262.SGRA_1766	7.377e-166	527.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HKD3_k127_5256465_7	760192.Halhy_3304	3.99e-59	213.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD3_k127_5256465_5	1122176.KB903555_gene3761	7.139e-86	298.0	COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,1IPTD@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD3_k127_5256465_0	1123276.KB893279_gene2060	1.087e-256	798.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,47KRX@768503|Cytophagia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD3_k127_5256465_12	760192.Halhy_3109	1.687e-20	94.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1ITVV@117747|Sphingobacteriia	976|Bacteroidetes	C	ATP synthase	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
HKD3_k127_5256465_1	760192.Halhy_3118	3.725e-178	568.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1INWM@117747|Sphingobacteriia	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
HKD3_k127_5256465_9	1356852.N008_11205	1.654e-49	193.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
HKD3_k127_5256465_6	1122176.KB903543_gene611	5.482e-81	277.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,1IXKQ@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_5256465_3	1122176.KB903543_gene612	3.168e-106	358.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1IXEP@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_5256465_4	1122179.KB890427_gene3882	7.649e-92	315.0	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_5256465_11	1286632.P278_05880	5.331e-37	143.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1I2SA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HKD3_k127_5256465_10	1122176.KB903556_gene4062	2.183e-48	187.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1IPE9@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
HKD3_k127_5276470_2	1408473.JHXO01000006_gene1174	1.384e-48	183.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,2FNEZ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_5276470_0	1122179.KB890418_gene3721	3.393e-218	700.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD3_k127_5276470_1	1122176.KB903531_gene3000	2.566e-102	338.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1IP3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
HKD3_k127_5287268_2	706436.HMPREF9074_07014	6.13e-79	281.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia,1EQW4@1016|Capnocytophaga	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD3_k127_5287268_1	1439940.BAY1663_02800	2.982e-81	278.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD3_k127_5287268_4	1317122.ATO12_03775	3.419e-41	161.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia,2YGX1@290174|Aquimarina	976|Bacteroidetes	O	Glutathione peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD3_k127_5287268_0	760192.Halhy_3003	3.678e-134	449.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_5287268_3	414684.RC1_3097	1.56e-67	238.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,2JP84@204441|Rhodospirillales	204441|Rhodospirillales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HKD3_k127_5346293_11	411477.PARMER_00516	8.169e-37	150.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia,22XCB@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_5346293_0	1158294.JOMI01000007_gene49	3.186e-185	591.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,2FNMZ@200643|Bacteroidia	976|Bacteroidetes	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
HKD3_k127_5346293_2	1122176.KB903609_gene5168	9.988e-160	513.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1IP3N@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
HKD3_k127_5346293_3	1122179.KB890424_gene3578	1.673e-154	525.0	COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,1IPNG@117747|Sphingobacteriia	976|Bacteroidetes	M	export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
HKD3_k127_5346293_1	760192.Halhy_6284	3.699e-171	540.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1IPW2@117747|Sphingobacteriia	976|Bacteroidetes	GM	NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_5346293_10	760192.Halhy_6283	1.008e-40	172.0	2EA9Q@1|root,334E4@2|Bacteria,4NX5I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5346293_5	760192.Halhy_6282	2.231e-91	316.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1IQKA@117747|Sphingobacteriia	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
HKD3_k127_5346293_8	1122236.KB905142_gene479	1.866e-53	200.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,2KKBG@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
HKD3_k127_5346293_4	1122176.KB903554_gene3859	8.646e-112	373.0	COG0626@1|root,COG0626@2|Bacteria,4NJRK@976|Bacteroidetes,1IP3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_5346293_7	242619.PG_1311	4.937e-56	201.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,2FSMW@200643|Bacteroidia,22XUV@171551|Porphyromonadaceae	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD3_k127_5346293_6	760192.Halhy_0103	8.303e-90	304.0	COG0604@1|root,COG0604@2|Bacteria,4NGIY@976|Bacteroidetes,1IPRS@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HKD3_k127_5351155_0	1356852.N008_04075	2.69e-141	466.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,47M30@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
HKD3_k127_5351155_1	1107311.Q767_09415	2.189e-25	119.0	28MCN@1|root,30KCD@2|Bacteria,4P9R9@976|Bacteroidetes,1INFZ@117743|Flavobacteriia,2NZGY@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5386782_2	1122176.KB903539_gene1331	3.665e-34	137.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia	976|Bacteroidetes	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HKD3_k127_5386782_3	314607.KB13_1288	2.29e-32	127.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1KQZD@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_5386782_1	1313421.JHBV01000032_gene1566	5.283e-137	439.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1IPAD@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD3_k127_5386782_0	1313301.AUGC01000005_gene226	2.213e-151	483.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD3_k127_5386782_4	1121904.ARBP01000003_gene6211	1.465e-23	109.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
HKD3_k127_5395128_4	1157708.KB907453_gene4251	8.18e-17	81.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,4ACNH@80864|Comamonadaceae	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD3_k127_5395128_1	1122605.KB893626_gene2686	1.418e-58	212.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_5395128_2	1121104.AQXH01000001_gene1299	3.612e-36	160.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,HisKA_3,His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_5395128_3	313595.P700755_000232	8.246e-27	130.0	COG2866@1|root,COG3291@1|root,COG4935@1|root,COG2866@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,4C2CE@83612|Psychroflexus	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36
HKD3_k127_5395128_0	926562.Oweho_2795	3.814e-207	715.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,CARDB,Calx-beta,Cleaved_Adhesin,DUF4465,Glyco_tran_WbsX,fn3
HKD3_k127_5428772_2	1121104.AQXH01000007_gene449	1.848e-47	181.0	2DKXC@1|root,30RJ8@2|Bacteria,4NJDT@976|Bacteroidetes,1IWNG@117747|Sphingobacteriia	976|Bacteroidetes	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
HKD3_k127_5428772_3	1250278.JQNQ01000001_gene3516	1.375e-35	143.0	COG2076@1|root,COG2076@2|Bacteria,4NQ4U@976|Bacteroidetes,1I2X4@117743|Flavobacteriia	976|Bacteroidetes	P	Small multidrug resistance protein	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
HKD3_k127_5428772_1	1122176.KB903541_gene211	3.199e-48	181.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1IT3W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HKD3_k127_5428772_0	760192.Halhy_2070	1.159e-93	332.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
HKD3_k127_543642_0	1122179.KB890427_gene3903	1.496e-190	602.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IP5K@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD3_k127_543642_1	700598.Niako_2127	1.347e-56	210.0	28MAS@1|root,318XW@2|Bacteria,4PPYP@976|Bacteroidetes,1IYW2@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
HKD3_k127_5492127_0	1122176.KB903576_gene4992	1.664e-97	336.0	COG1073@1|root,COG1073@2|Bacteria,4PM54@976|Bacteroidetes,1IUAN@117747|Sphingobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
HKD3_k127_5544798_4	1122179.KB890414_gene1731	1.16e-44	165.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
HKD3_k127_5544798_7	1123276.KB893251_gene3582	5.805e-34	134.0	COG2346@1|root,COG2346@2|Bacteria,4NQCV@976|Bacteroidetes,47R5V@768503|Cytophagia	976|Bacteroidetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD3_k127_5544798_1	946077.W5A_02095	1.212e-68	252.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1HXSS@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
HKD3_k127_5544798_2	1416760.AYMS01000033_gene1415	4.826e-66	233.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia,47HQK@76831|Myroides	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD3_k127_5544798_6	1122915.AUGY01000099_gene3654	1.457e-39	157.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_5544798_0	760192.Halhy_2220	5.083e-160	513.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
HKD3_k127_5544798_5	760192.Halhy_1878	9.617e-44	174.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd
HKD3_k127_5544798_3	1485543.JMME01000001_gene1358	7.077e-45	178.0	COG2348@1|root,COG2348@2|Bacteria,1V67I@1239|Firmicutes	1239|Firmicutes	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
HKD3_k127_5544798_10	1122176.KB903598_gene4595	2.862e-11	76.0	29YDI@1|root,30K80@2|Bacteria,4P7P6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5544798_9	1121934.AUDX01000022_gene2989	5.024e-15	88.0	COG0438@1|root,COG2120@1|root,COG0438@2|Bacteria,COG2120@2|Bacteria,2GJ57@201174|Actinobacteria,4FKV0@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1,PIG-L
HKD3_k127_5544798_8	272123.Anacy_3781	2.592e-28	126.0	COG1216@1|root,COG1216@2|Bacteria,1G3NM@1117|Cyanobacteria,1HMKB@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_5591848_2	926562.Oweho_0625	1.263e-170	554.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_5591848_5	880074.BARVI_05610	1.493e-51	198.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
HKD3_k127_5591848_0	760192.Halhy_5958	8.551e-189	597.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD3_k127_5591848_6	1211813.CAPH01000017_gene816	7.045e-49	184.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,2FXYF@200643|Bacteroidia,22UG6@171550|Rikenellaceae	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD3_k127_5591848_7	760192.Halhy_0191	4.039e-38	153.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1IQWM@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
HKD3_k127_5591848_8	760192.Halhy_0780	1.93e-30	132.0	COG1845@1|root,COG1845@2|Bacteria,4NU0C@976|Bacteroidetes	976|Bacteroidetes	C	heme copper-type cytochrome quinol oxidase, subunit 3	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_5591848_3	1122176.KB903619_gene5463	8.293e-137	462.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1IYME@117747|Sphingobacteriia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
HKD3_k127_5591848_1	1122176.KB903538_gene1557	1.395e-186	589.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_5591848_4	1454007.JAUG01000014_gene1817	1.557e-130	429.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1IPZ7@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_5601855_6	1235803.C825_01361	9.986e-96	320.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,2FMX2@200643|Bacteroidia,22W77@171551|Porphyromonadaceae	976|Bacteroidetes	D	Chromosome partitioning protein ParA	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD3_k127_5601855_8	1121373.KB903624_gene2437	1.769e-80	278.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,47K9I@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD3_k127_5601855_11	1168289.AJKI01000002_gene2255	1.855e-23	108.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,2FTY0@200643|Bacteroidia,3XK1I@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5601855_1	1122176.KB903598_gene4658	4.853e-241	756.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes	976|Bacteroidetes	J	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HKD3_k127_5601855_2	760192.Halhy_0989	3.917e-220	707.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HKD3_k127_5601855_10	760192.Halhy_0987	6.159e-49	187.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1ISB1@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA methyltransferase, RsmD	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD3_k127_5601855_5	1124780.ANNU01000040_gene394	1.061e-117	387.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD3_k127_5601855_0	760192.Halhy_6186	1.344e-320	990.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD3_k127_5601855_9	1122176.KB903538_gene1563	5.922e-60	221.0	2CA1R@1|root,3391I@2|Bacteria,4NXBJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
HKD3_k127_5601855_3	1270196.JCKI01000006_gene2758	1.97e-132	428.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1IRN1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HKD3_k127_5601855_7	1211813.CAPH01000018_gene956	1.592e-87	302.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,2FMVX@200643|Bacteroidia,22UXU@171550|Rikenellaceae	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD3_k127_5601855_4	760192.Halhy_6532	3.687e-121	400.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
HKD3_k127_567035_0	760192.Halhy_2468	9.161e-128	430.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
HKD3_k127_567035_3	760192.Halhy_4228	1.109e-100	341.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
HKD3_k127_567035_2	1122179.KB890436_gene1237	2.841e-117	389.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
HKD3_k127_567035_1	1313301.AUGC01000005_gene322	2.161e-126	416.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_5684209_4	1123277.KB893174_gene5927	5.127e-80	283.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_5684209_6	1120966.AUBU01000003_gene1733	1.223e-64	231.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_5684209_3	1086011.HJ01_00554	1.869e-87	301.0	COG0697@1|root,COG0697@2|Bacteria,4NK8U@976|Bacteroidetes,1I01E@117743|Flavobacteriia,2NV5M@237|Flavobacterium	976|Bacteroidetes	EG	drug metabolite-transporting permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_5684209_5	391587.KAOT1_04615	2.188e-77	274.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1HY38@117743|Flavobacteriia	976|Bacteroidetes	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD3_k127_5684209_1	1185876.BN8_03582	4.173e-132	454.0	COG3540@1|root,COG3540@2|Bacteria,4NDUS@976|Bacteroidetes,47NKM@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
HKD3_k127_5684209_11	1397528.Q671_14945	0.0006911	42.0	COG0582@1|root,COG0582@2|Bacteria,1QYZQ@1224|Proteobacteria,1RSG8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD3_k127_5684209_2	1313421.JHBV01000022_gene4733	2.349e-105	351.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1IXIZ@117747|Sphingobacteriia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
HKD3_k127_5684209_0	1122605.KB893626_gene2453	3.05e-142	465.0	COG1231@1|root,COG1231@2|Bacteria,4NJU7@976|Bacteroidetes,1IYQ9@117747|Sphingobacteriia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
HKD3_k127_5684209_9	592029.DDD_2545	5.643e-25	112.0	2EB4Z@1|root,30YQX@2|Bacteria,4PCMU@976|Bacteroidetes,1IN34@117743|Flavobacteriia,3HM7G@363408|Nonlabens	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5684209_7	1121904.ARBP01000007_gene2973	3.716e-42	162.0	COG0746@1|root,COG0746@2|Bacteria,4NMYW@976|Bacteroidetes,47NQP@768503|Cytophagia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HKD3_k127_5684209_8	1131812.JQMS01000001_gene148	1.207e-25	123.0	COG1345@1|root,COG2273@1|root,COG3209@1|root,COG3291@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG1345@2|Bacteria,COG2273@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4NHMH@976|Bacteroidetes,1IIJN@117743|Flavobacteriia,2P0DQ@237|Flavobacterium	976|Bacteroidetes	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
HKD3_k127_5684209_10	1122179.KB890414_gene1864	5.949e-09	69.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
HKD3_k127_5975144_1	1218108.KB908299_gene3313	4.64e-96	319.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,1HZIX@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD3_k127_5975144_0	1313421.JHBV01000031_gene1381	1.09e-110	368.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1INPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
HKD3_k127_5975144_2	1122176.KB903574_gene4814	1.632e-72	267.0	COG3210@1|root,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	976|Bacteroidetes	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	HYR
HKD3_k127_6017422_2	1166018.FAES_4888	1.493e-13	80.0	COG0457@1|root,COG4191@1|root,COG0457@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47KW1@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
HKD3_k127_6017422_1	760192.Halhy_0215	1.313e-16	81.0	COG0076@1|root,COG0076@2|Bacteria,4NJ2F@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15,4.1.2.27	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	M00027,M00100	R00261,R00489,R01682,R02464,R02466,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
HKD3_k127_6030484_0	1122176.KB903532_gene2517	0.0	1405.0	COG3383@1|root,COG3383@2|Bacteria,4PKV4@976|Bacteroidetes,1IX2V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	hndD	-	1.12.1.3,1.17.1.9	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
HKD3_k127_6030484_1	1191523.MROS_0497	4.119e-52	209.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_6032003_4	760192.Halhy_6398	4.431e-52	207.0	COG2885@1|root,COG3292@1|root,COG2885@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	M	chlorophyll binding	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
HKD3_k127_6032003_5	700598.Niako_2442	7.18e-05	56.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IR3V@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_6032003_0	1122176.KB903540_gene11	1.437e-177	564.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,1IREZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	yisS	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_6032003_3	1501230.ET33_18765	3.037e-55	201.0	COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,26WYG@186822|Paenibacillaceae	91061|Bacilli	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HKD3_k127_6032003_1	1122176.KB903550_gene4352	7.993e-137	451.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_6032003_2	1121481.AUAS01000007_gene960	1.645e-70	245.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HKD3_k127_6054816_6	760192.Halhy_5224	2.648e-72	251.0	COG0507@1|root,COG0507@2|Bacteria,4P0TS@976|Bacteroidetes,1J07W@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1
HKD3_k127_6054816_11	1122179.KB890469_gene479	8.599e-30	128.0	COG1266@1|root,COG1266@2|Bacteria,4NIKQ@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_6054816_0	760192.Halhy_5692	4.578e-258	805.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1IP4J@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HKD3_k127_6054816_3	1313421.JHBV01000007_gene4252	2.753e-79	286.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,1IWAS@117747|Sphingobacteriia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HKD3_k127_6054816_5	755732.Fluta_3018	3.735e-76	263.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia,2PBNT@246874|Cryomorphaceae	976|Bacteroidetes	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_6054816_13	1121373.KB903621_gene1833	9.624e-25	109.0	COG0526@1|root,COG0607@1|root,COG0526@2|Bacteria,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47PJB@768503|Cytophagia	976|Bacteroidetes	OP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
HKD3_k127_6054816_9	1270196.JCKI01000004_gene1143	2.139e-32	128.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1J0R1@117747|Sphingobacteriia	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD3_k127_6054816_12	1121373.KB903625_gene3212	1.475e-28	121.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47R62@768503|Cytophagia	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_6054816_10	929562.Emtol_0587	7.615e-31	124.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47SAY@768503|Cytophagia	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_6054816_4	760192.Halhy_4227	3.423e-79	276.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
HKD3_k127_6054816_8	760192.Halhy_0456	7.206e-34	145.0	28M5H@1|root,2ZAJ9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6054816_2	929556.Solca_3818	4.56e-119	407.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_2,TPR_8
HKD3_k127_6054816_1	760192.Halhy_6306	2.296e-152	492.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD3_k127_6054816_7	1185876.BN8_06312	8.794e-43	165.0	COG2318@1|root,COG2318@2|Bacteria,4NRSP@976|Bacteroidetes,47XVC@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
HKD3_k127_6055686_22	1122176.KB903544_gene722	5.049e-28	122.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_6055686_8	1122176.KB903544_gene723	1.015e-76	265.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1IS0F@117747|Sphingobacteriia	976|Bacteroidetes	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
HKD3_k127_6055686_7	1122179.KB890452_gene4658	1.233e-91	314.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
HKD3_k127_6055686_13	314345.SPV1_08983	8.315e-50	186.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD3_k127_6055686_6	1122176.KB903548_gene1143	1.327e-97	331.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_6055686_15	1313421.JHBV01000032_gene1627	4.161e-45	173.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,1IT2H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HKD3_k127_6055686_9	760192.Halhy_2634	1.134e-75	266.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1IQ34@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HKD3_k127_6055686_4	1122179.KB890417_gene3290	3.978e-117	387.0	COG0857@1|root,COG0857@2|Bacteria	2|Bacteria	C	belongs to the CobB CobQ family	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
HKD3_k127_6055686_19	760192.Halhy_3314	7.82e-36	142.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1ITEI@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
HKD3_k127_6055686_14	1122176.KB903560_gene3561	2.144e-45	172.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1ISJI@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HKD3_k127_6055686_17	760192.Halhy_3310	8.921e-42	154.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1ISSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HKD3_k127_6055686_16	1122176.KB903560_gene3563	1.252e-44	174.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1IRUM@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HKD3_k127_6055686_20	1120965.AUBV01000010_gene2852	5.356e-32	139.0	COG3386@1|root,COG3386@2|Bacteria,4NHFU@976|Bacteroidetes,47M00@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF4394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394
HKD3_k127_6055686_0	929556.Solca_1162	5.295e-200	632.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD3_k127_6055686_3	1122179.KB890480_gene3093	1.011e-123	406.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_6055686_5	760192.Halhy_3065	2.483e-102	350.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HKD3_k127_6055686_10	760192.Halhy_4310	2.354e-62	224.0	COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,1IS83@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD3_k127_6055686_11	1122176.KB903534_gene2188	3.852e-55	198.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1IS0K@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
HKD3_k127_6055686_1	742725.HMPREF9450_01524	2.625e-180	594.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,2FMM3@200643|Bacteroidia,22TZS@171550|Rikenellaceae	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
HKD3_k127_6055686_21	887929.HMP0721_1707	1.698e-31	128.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,25VRF@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HKD3_k127_6055686_2	760192.Halhy_3971	2.219e-155	512.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1IPZ1@117747|Sphingobacteriia	976|Bacteroidetes	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
HKD3_k127_6055686_18	1122176.KB903532_gene2569	1.669e-37	154.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,1IYQF@117747|Sphingobacteriia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
HKD3_k127_6055686_12	760192.Halhy_3973	4.128e-53	195.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1IQB4@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
HKD3_k127_6070294_10	865937.Gilli_0558	1.676e-24	121.0	COG1520@1|root,COG2304@1|root,COG3391@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG3391@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia,2P5SV@244698|Gillisia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
HKD3_k127_6070294_14	391587.KAOT1_09806	7.284e-05	57.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NM41@976|Bacteroidetes	976|Bacteroidetes	V	Fibronectin type III	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,MAM,fn3
HKD3_k127_6070294_5	1122176.KB903579_gene4846	4.557e-51	193.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C,DUF4150,PorP_SprF
HKD3_k127_6070294_13	1313421.JHBV01000023_gene5067	7.021e-11	76.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4PPAV@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD3_k127_6070294_2	760192.Halhy_3864	5.258e-101	364.0	COG1361@1|root,COG3209@1|root,COG4886@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG4886@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
HKD3_k127_6070294_4	760192.Halhy_3866	9.621e-77	289.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Beta_helix,Calx-beta,DUF4347,SLH,VCBS
HKD3_k127_6070294_7	925409.KI911562_gene634	2.117e-33	141.0	COG2197@1|root,COG2197@2|Bacteria,4NSGV@976|Bacteroidetes,1ITSZ@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_6070294_6	880526.KE386488_gene478	2.456e-42	166.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,2FPU3@200643|Bacteroidia,22U5V@171550|Rikenellaceae	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HKD3_k127_6070294_9	760192.Halhy_2387	1.755e-25	120.0	COG1181@1|root,COG2815@1|root,COG1181@2|Bacteria,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes	976|Bacteroidetes	M	Pasta domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
HKD3_k127_6070294_11	761193.Runsl_1062	2.177e-17	85.0	COG0607@1|root,COG0607@2|Bacteria,4NVM6@976|Bacteroidetes,47RAG@768503|Cytophagia	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_6070294_3	1122176.KB903545_gene920	2.176e-81	284.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes,1IPNT@117747|Sphingobacteriia	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_6070294_8	1122176.KB903541_gene272	1.829e-28	123.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1IRVW@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
HKD3_k127_6070294_12	1122176.KB903535_gene1977	3.643e-17	89.0	2EHKQ@1|root,33BCG@2|Bacteria,4NZQK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4348
HKD3_k127_6070294_1	1313301.AUGC01000010_gene889	6.58e-117	386.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
HKD3_k127_6070294_0	1122176.KB903541_gene207	7.418e-197	620.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1INQX@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
HKD3_k127_6072291_4	760192.Halhy_0861	5.034e-73	251.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1INMN@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
HKD3_k127_6072291_5	1122176.KB903587_gene4389	1.382e-60	221.0	COG4372@1|root,COG4372@2|Bacteria,4NVE9@976|Bacteroidetes,1J0WS@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6072291_2	1122176.KB903587_gene4390	1.922e-81	279.0	COG0417@1|root,COG0417@2|Bacteria,4PKQ5@976|Bacteroidetes,1J0WR@117747|Sphingobacteriia	976|Bacteroidetes	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
HKD3_k127_6072291_0	760192.Halhy_6134	8.276e-161	523.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1IPWT@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD3_k127_6072291_1	1122176.KB903556_gene4105	1.108e-152	499.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IQIN@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
HKD3_k127_6072291_3	1392488.JHZY01000004_gene2539	6.962e-79	287.0	COG2911@1|root,COG3209@1|root,COG5184@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
HKD3_k127_6086676_1	1049564.TevJSym_aq00710	1.44e-148	483.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
HKD3_k127_6086676_5	1049564.TevJSym_aq00810	3.183e-75	287.0	COG0674@1|root,COG1013@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	forE	-	1.2.7.1	ko:K00171,ko:K00172,ko:K02573,ko:K03737,ko:K13795,ko:K18930	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,Fer4,Fer4_4,Fer4_6,Fer4_9,Nitroreductase,PFOR_II,POR,POR_N,TPP_enzyme_C
HKD3_k127_6086676_8	557598.LHK_01444	2.056e-10	75.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	pyruvate flavodoxin ferredoxin oxidoreductase	porA	-	1.2.1.58,1.2.7.1	ko:K00169,ko:K18355	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
HKD3_k127_6086676_3	1049564.TevJSym_bb00010	1.336e-93	315.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
HKD3_k127_6086676_4	1049564.TevJSym_bb00030	9.592e-84	308.0	COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
HKD3_k127_6086676_2	1049564.TevJSym_bb00040	1.211e-117	386.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD3_k127_6086676_0	1049564.TevJSym_bb00050	5.162e-257	807.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HKD3_k127_6086676_6	714943.Mucpa_1801	1.095e-65	237.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1ITYF@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_6086676_7	1336243.JAEA01000005_gene1559	2.406e-55	201.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,1JX36@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HKD3_k127_6087134_0	1122179.KB890429_gene3651	1.616e-70	261.0	COG2152@1|root,COG3210@1|root,COG2152@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Haemagg_act,Laminin_G_3
HKD3_k127_6104171_1	1002367.HMPREF0673_02349	7.25e-07	55.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,2G2R1@200643|Bacteroidia	976|Bacteroidetes	O	Peptidase, S8 S53 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_6104171_0	1408433.JHXV01000001_gene768	4.131e-143	480.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes	976|Bacteroidetes	O	Peptidase, S8 S53 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_6104690_2	1122179.KB890413_gene4782	6.37e-77	263.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1IP6G@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_6104690_0	1122176.KB903571_gene4786	9.202e-158	519.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_16,TPR_2,TPR_8
HKD3_k127_6104690_1	742726.HMPREF9448_02685	9.644e-127	418.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia,22WNP@171551|Porphyromonadaceae	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD3_k127_6134778_1	794903.OPIT5_09530	4.731e-108	376.0	COG0209@1|root,COG0209@2|Bacteria,46XFZ@74201|Verrucomicrobia,3K76W@414999|Opitutae	414999|Opitutae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	-
HKD3_k127_6134778_4	1121890.AUDO01000011_gene398	5.063e-88	300.0	COG0668@1|root,COG0668@2|Bacteria,4NH7C@976|Bacteroidetes,1ICX5@117743|Flavobacteriia,2NVTM@237|Flavobacterium	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HKD3_k127_6134778_6	649349.Lbys_2623	2.446e-39	154.0	2DBUE@1|root,2ZB5Q@2|Bacteria,4NM7Y@976|Bacteroidetes,47S40@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
HKD3_k127_6134778_3	1288963.ADIS_1567	3.917e-104	349.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HKD3_k127_6134778_2	1288963.ADIS_1567	1.651e-105	359.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HKD3_k127_6134778_0	1392490.JHZX01000001_gene126	9.554e-213	706.0	2DBTS@1|root,2ZB0P@2|Bacteria,4NGP7@976|Bacteroidetes,1IKCE@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD3_k127_6134778_5	313595.P700755_000563	3.191e-52	213.0	COG3227@1|root,COG3227@2|Bacteria,4PM8R@976|Bacteroidetes,1HZ4E@117743|Flavobacteriia,4C492@83612|Psychroflexus	976|Bacteroidetes	E	Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD3_k127_6143730_9	471854.Dfer_2847	8.64e-31	133.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,47KV8@768503|Cytophagia	976|Bacteroidetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HKD3_k127_6143730_3	761193.Runsl_1280	5.008e-87	298.0	COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,47JWN@768503|Cytophagia	976|Bacteroidetes	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_6143730_2	1453500.AT05_09755	4.815e-127	418.0	COG0189@1|root,COG0189@2|Bacteria,4PKRE@976|Bacteroidetes,1IJDG@117743|Flavobacteriia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,Dala_Dala_lig_C
HKD3_k127_6143730_10	1123276.KB893245_gene1603	5.707e-10	72.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,47YID@768503|Cytophagia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
HKD3_k127_6143730_1	1122176.KB903565_gene3214	1.132e-143	466.0	COG2308@1|root,COG2308@2|Bacteria,4NG4D@976|Bacteroidetes,1IRDC@117747|Sphingobacteriia	976|Bacteroidetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6143730_7	1144313.PMI10_01027	1.374e-36	147.0	2FHWS@1|root,30YNE@2|Bacteria,4PCHK@976|Bacteroidetes,1ID3I@117743|Flavobacteriia,2NX5S@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6143730_4	616991.JPOO01000003_gene2628	1.739e-73	257.0	COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1HZTP@117743|Flavobacteriia	976|Bacteroidetes	F	GMP synthase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
HKD3_k127_6143730_0	616991.JPOO01000003_gene2630	3.734e-144	463.0	COG0189@1|root,COG0189@2|Bacteria,4NFK1@976|Bacteroidetes,1HZS6@117743|Flavobacteriia	976|Bacteroidetes	HJ	Glutathione synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6143730_8	761193.Runsl_1657	1.306e-32	129.0	COG0296@1|root,COG0296@2|Bacteria,4NSTP@976|Bacteroidetes,47Q8H@768503|Cytophagia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
HKD3_k127_6143730_6	760192.Halhy_6119	5.996e-41	169.0	COG0457@1|root,COG2314@1|root,COG0457@2|Bacteria,COG2314@2|Bacteria	2|Bacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Pilin,SHOCT,TM2,TerB_C,TerB_N
HKD3_k127_6143730_5	880070.Cycma_3864	2.877e-45	182.0	COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47N72@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_19,TPR_8
HKD3_k127_618724_10	215803.DB30_2773	6.107e-06	49.0	COG1361@1|root,COG3055@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_618724_6	1123278.KB893555_gene4002	1.59e-59	230.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47JDV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_618724_4	1123278.KB893555_gene4002	4.745e-64	243.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47JDV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_618724_1	1123277.KB893195_gene5528	1.413e-104	346.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47PT3@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_618724_5	1123278.KB893555_gene4002	1.511e-59	231.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47JDV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_618724_9	760192.Halhy_3047	2.585e-14	86.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
HKD3_k127_618724_11	1089547.KB913013_gene1461	1.11e-05	58.0	2DETR@1|root,2ZP81@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6
HKD3_k127_618724_0	1237149.C900_03097	0.0	1811.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
HKD3_k127_618724_3	1237149.C900_03096	1.971e-86	299.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,47JRK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
HKD3_k127_618724_8	1353276.JADR01000006_gene1080	6.932e-16	93.0	COG5295@1|root,COG5295@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_618724_2	1121889.AUDM01000002_gene337	7.429e-100	357.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia,2NVE3@237|Flavobacterium	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_618724_12	929562.Emtol_1027	1.132e-05	51.0	COG1044@1|root,COG5295@1|root,COG1044@2|Bacteria,COG5295@2|Bacteria,4NKG1@976|Bacteroidetes,47NK6@768503|Cytophagia	976|Bacteroidetes	MUW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
HKD3_k127_6191198_0	760192.Halhy_2507	2.745e-287	887.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HKD3_k127_6191198_1	1122176.KB903548_gene1163	2.391e-266	833.0	COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,1IV0R@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
HKD3_k127_622915_1	760192.Halhy_4682	1.223e-216	678.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IQCY@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_622915_3	760192.Halhy_4683	8.457e-73	254.0	COG0664@1|root,COG0664@2|Bacteria,4NJR1@976|Bacteroidetes,1IQRM@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_622915_2	743722.Sph21_1685	1.439e-134	441.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1IP4Q@117747|Sphingobacteriia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_622915_0	1122176.KB903548_gene1180	7.715e-221	711.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPM9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD3_k127_622915_4	1122179.KB890420_gene2424	4.72e-13	69.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HKD3_k127_6275574_9	1250232.JQNJ01000001_gene643	4.192e-129	420.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
HKD3_k127_6275574_3	1341155.FSS13T_09020	1.06e-201	635.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1HX18@117743|Flavobacteriia,2NSI7@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD3_k127_6275574_16	760192.Halhy_4476	7.564e-80	271.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD3_k127_6275574_7	1122176.KB903587_gene4526	2.475e-132	433.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1INYI@117747|Sphingobacteriia	976|Bacteroidetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HKD3_k127_6275574_27	688270.Celal_3108	2.369e-41	156.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1I2YH@117743|Flavobacteriia,1F985@104264|Cellulophaga	976|Bacteroidetes	J	Endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HKD3_k127_6275574_34	1178825.ALIH01000003_gene2214	1.436e-20	92.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1I53M@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HKD3_k127_6275574_33	1122176.KB903587_gene4529	1.201e-20	98.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1ISWG@117747|Sphingobacteriia	976|Bacteroidetes	S	acr, cog1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
HKD3_k127_6275574_26	760192.Halhy_2405	1.229e-49	184.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_16,TPR_8
HKD3_k127_6275574_29	471854.Dfer_3039	1.095e-30	124.0	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_6275574_24	700598.Niako_5487	3.585e-57	203.0	COG1607@1|root,COG1607@2|Bacteria,4NNQF@976|Bacteroidetes,1IT3M@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_6275574_15	1341181.FLJC2902T_21840	2.803e-82	279.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1HX2T@117743|Flavobacteriia,2NTWM@237|Flavobacterium	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
HKD3_k127_6275574_14	760192.Halhy_1810	2.33e-94	319.0	COG0730@1|root,COG0730@2|Bacteria,4PKBI@976|Bacteroidetes,1ISPZ@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_6275574_8	401053.AciPR4_3641	9.53e-132	437.0	COG0076@1|root,COG0076@2|Bacteria,3Y365@57723|Acidobacteria,2JP4F@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
HKD3_k127_6275574_12	1123008.KB905703_gene556	1.416e-107	366.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,2FMYJ@200643|Bacteroidia,22W0H@171551|Porphyromonadaceae	976|Bacteroidetes	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
HKD3_k127_6275574_23	1223410.KN050846_gene1541	6.579e-58	208.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1I33C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_6275574_2	1122176.KB903548_gene1135	1.598e-203	646.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1IQI6@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1233 Phytoene dehydrogenase and related	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_6275574_10	760192.Halhy_2488	1.018e-111	366.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1IP80@117747|Sphingobacteriia	976|Bacteroidetes	I	Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
HKD3_k127_6275574_22	760192.Halhy_4786	3.753e-59	209.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1ISJ5@117747|Sphingobacteriia	976|Bacteroidetes	I	Beta-carotene hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
HKD3_k127_6275574_25	760192.Halhy_2487	1.039e-53	199.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,1IRYT@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM lycopene cyclase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6275574_5	760192.Halhy_4547	3.023e-163	528.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IQCY@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_6275574_6	760192.Halhy_4547	4.863e-156	505.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IQCY@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_6275574_30	760192.Halhy_4548	4.214e-30	126.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD3_k127_6275574_1	760192.Halhy_0840	4.731e-204	655.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1IP14@117747|Sphingobacteriia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
HKD3_k127_6275574_18	760192.Halhy_0227	5.124e-76	273.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1IT3V@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,SusF_SusE
HKD3_k127_6275574_20	1122176.KB903561_gene3588	3.53e-70	252.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1ISF2@117747|Sphingobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_6275574_4	1122176.KB903561_gene3587	1.492e-172	579.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,1IWR7@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_6275574_28	1122176.KB903561_gene3586	5.412e-40	156.0	COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_6275574_17	1122176.KB903619_gene5331	4.962e-79	275.0	2DMBB@1|root,32GIQ@2|Bacteria,4NSXP@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4465
HKD3_k127_6275574_19	1122176.KB903619_gene5332	1.349e-74	276.0	COG4206@1|root,COG4206@2|Bacteria,4NED9@976|Bacteroidetes,1IQW0@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB-dependent receptor plug	btuB	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HKD3_k127_6275574_0	760192.Halhy_2578	1.512e-232	747.0	COG1629@1|root,COG4772@1|root,COG1629@2|Bacteria,COG4772@2|Bacteria,4P4MW@976|Bacteroidetes,1IRE6@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_6275574_13	1122176.KB903544_gene800	5.221e-101	343.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1IX4W@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_6275574_36	553177.CAPSP0001_0151	6.696e-13	76.0	COG1452@1|root,COG1452@2|Bacteria,4PKIN@976|Bacteroidetes,1IJA7@117743|Flavobacteriia,1EQNA@1016|Capnocytophaga	976|Bacteroidetes	M	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	-	-	-	-	-	-	-	-	-	LptC
HKD3_k127_6275574_11	1122176.KB903544_gene801	1.831e-111	389.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1J19E@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SprB
HKD3_k127_6275574_31	926562.Oweho_1634	1.295e-25	116.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia,2PAW8@246874|Cryomorphaceae	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HKD3_k127_6275574_32	760192.Halhy_2946	2.013e-24	107.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1ITNI@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
HKD3_k127_6275574_21	1313421.JHBV01000035_gene2572	1.474e-62	220.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1IPC1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD3_k127_6281685_0	1121895.Q765_12815	2.211e-129	435.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia,2NTEI@237|Flavobacterium	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,TPR_8
HKD3_k127_6291188_6	1122176.KB903531_gene3070	1.049e-11	74.0	COG3087@1|root,COG3087@2|Bacteria	2|Bacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	2.7.7.7,5.4.99.21	ko:K02343,ko:K06182,ko:K08372,ko:K12065,ko:K16291	ko00230,ko00240,ko01100,ko02020,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02044,ko03009,ko03032,ko03400	3.A.7.11.1	-	-	Gram_pos_anchor,NYN,SPOR
HKD3_k127_6291188_4	1122179.KB890497_gene2814	7.012e-53	192.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1IRXR@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD3_k127_6291188_0	760192.Halhy_1843	2.576e-291	916.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,1J0WW@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
HKD3_k127_6291188_2	1122176.KB903554_gene3847	4.133e-94	314.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1IPVS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HKD3_k127_6291188_5	290512.Paes_1770	4.597e-24	105.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP,DegT_DnrJ_EryC1
HKD3_k127_6291188_3	1166018.FAES_3811	8.28e-80	289.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
HKD3_k127_6346792_6	997884.HMPREF1068_02722	0.0008316	44.0	COG2273@1|root,COG2273@2|Bacteria,4NZQS@976|Bacteroidetes,2FZNQ@200643|Bacteroidia,4AUWE@815|Bacteroidaceae	976|Bacteroidetes	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
HKD3_k127_6346792_1	1121272.KB903254_gene6721	2.398e-33	139.0	2E3IT@1|root,32XW0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6346792_2	1121272.KB903254_gene6721	2.955e-33	137.0	2E3IT@1|root,32XW0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6346792_5	984262.SGRA_2285	7.935e-07	58.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GxGYxYP_C,GxGYxYP_N,NB-ARC,Sigma70_r2,Sigma70_r4_2,TPR_4
HKD3_k127_6346792_0	760192.Halhy_5986	8.74e-74	280.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,1IVXI@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4995 conserved	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
HKD3_k127_6346792_4	504487.JCM19302_2833	6.096e-15	74.0	COG0296@1|root,COG0296@2|Bacteria,4NJ7Z@976|Bacteroidetes,1HZ6E@117743|Flavobacteriia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
HKD3_k127_6363829_4	1122605.KB893627_gene2972	0.0003691	48.0	COG0810@1|root,COG0810@2|Bacteria,4NSYT@976|Bacteroidetes,1IT8E@117747|Sphingobacteriia	976|Bacteroidetes	M	Gram-negative bacterial tonB protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_C
HKD3_k127_6363829_2	1122605.KB893627_gene2973	1.234e-42	163.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6363829_0	760192.Halhy_2067	4.062e-295	917.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1IQV0@117747|Sphingobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_6363829_1	1122176.KB903543_gene659	2.962e-236	744.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1IQDQ@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD3_k127_6379602_10	1122176.KB903531_gene2807	5.735e-05	51.0	2FC5N@1|root,3449G@2|Bacteria,4P59J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6379602_0	1122179.KB890425_gene3493	1.175e-189	603.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1IPU8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	nagA	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_6379602_3	926562.Oweho_0819	3.046e-74	257.0	COG0794@1|root,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
HKD3_k127_6379602_2	926562.Oweho_0821	1.666e-109	364.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1HXM5@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
HKD3_k127_6379602_6	1408433.JHXV01000021_gene1637	1.595e-40	160.0	COG1778@1|root,COG1778@2|Bacteria,4NGXC@976|Bacteroidetes,1HX0H@117743|Flavobacteriia,2PAX2@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	2.7.7.43,2.7.7.92,3.1.3.45	ko:K03270,ko:K21749	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
HKD3_k127_6379602_9	1215092.PA6_028_01090	2.838e-05	55.0	2AHM9@1|root,317Z5@2|Bacteria,1QEQ4@1224|Proteobacteria,1TBI7@1236|Gammaproteobacteria,1YHPU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6379602_4	1008457.BAEX01000103_gene2191	1.657e-69	246.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia,47HTT@76831|Myroides	976|Bacteroidetes	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
HKD3_k127_6379602_8	760192.Halhy_3265	4.613e-25	116.0	COG3074@1|root,COG3074@2|Bacteria,4NQ7C@976|Bacteroidetes	976|Bacteroidetes	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6379602_7	1121396.KB892964_gene2021	2.595e-31	133.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,42VS0@68525|delta/epsilon subdivisions,2WSHH@28221|Deltaproteobacteria,2MNBW@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_6379602_5	313606.M23134_01176	1.369e-40	166.0	COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD3_k127_6379602_1	880070.Cycma_1629	4.861e-168	540.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,47MV2@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_6392209_0	1122176.KB903587_gene4517	1.279e-128	423.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD3_k127_6392209_1	1185876.BN8_03904	2.426e-56	209.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,47JZN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
HKD3_k127_6392209_2	1122176.KB903531_gene2951	1.631e-26	112.0	COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,1J0XR@117747|Sphingobacteriia	976|Bacteroidetes	H	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
HKD3_k127_6393704_29	1122176.KB903531_gene2951	5.468e-66	242.0	COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,1J0XR@117747|Sphingobacteriia	976|Bacteroidetes	H	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
HKD3_k127_6393704_7	1122176.KB903531_gene2952	2.281e-186	621.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1IPPH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
HKD3_k127_6393704_43	1469557.JSWF01000029_gene3410	7.283e-27	113.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded DNA-binding protein	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_6393704_16	1122176.KB903551_gene4248	2.553e-130	424.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1J098@117747|Sphingobacteriia	976|Bacteroidetes	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
HKD3_k127_6393704_14	926562.Oweho_0483	8.64e-143	470.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia,2PBJ7@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
HKD3_k127_6393704_11	1123248.KB893324_gene1697	2.43e-174	556.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,1IUWR@117747|Sphingobacteriia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_6393704_3	1122179.KB890432_gene4121	5.116e-256	805.0	COG0365@1|root,COG0365@2|Bacteria,4NINZ@976|Bacteroidetes,1IPMF@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD3_k127_6393704_6	1122176.KB903609_gene5133	7.793e-192	610.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1IPSQ@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01965,ko:K01968	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00373,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_6393704_10	1123277.KB893177_gene3543	7.155e-176	584.0	COG2133@1|root,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_3,PA14
HKD3_k127_6393704_50	745411.B3C1_07856	5.747e-09	65.0	COG3042@1|root,COG3042@2|Bacteria,1NIS8@1224|Proteobacteria,1SIG9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6393704_28	1313421.JHBV01000041_gene3502	9.328e-67	239.0	COG2932@1|root,COG2932@2|Bacteria,4NDUW@976|Bacteroidetes,1IQ7T@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
HKD3_k127_6393704_4	671143.DAMO_2383	7.671e-244	760.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	UPF0051
HKD3_k127_6393704_20	105559.Nwat_0645	7.716e-110	360.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HKD3_k127_6393704_26	1122176.KB903541_gene169	3.532e-69	251.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1IQF5@117747|Sphingobacteriia	976|Bacteroidetes	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HKD3_k127_6393704_13	472759.Nhal_0691	9.097e-155	514.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1WWTN@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
HKD3_k127_6393704_38	518766.Rmar_2026	1.599e-43	177.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1FJFU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Fe-S metabolism associated domain	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
HKD3_k127_6393704_42	1122176.KB903541_gene166	3.331e-27	127.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1ITW8@117747|Sphingobacteriia	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
HKD3_k127_6393704_36	925409.KI911562_gene2849	1.876e-46	173.0	COG1959@1|root,COG1959@2|Bacteria,4NY03@976|Bacteroidetes,1IXYJ@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD3_k127_6393704_48	871968.DESME_02010	7.325e-10	71.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PATR
HKD3_k127_6393704_32	1313421.JHBV01000041_gene3626	1.026e-62	231.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes	976|Bacteroidetes	L	Nuclease, EndA NucM family	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
HKD3_k127_6393704_37	760192.Halhy_5371	2.516e-45	175.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1IQ45@117747|Sphingobacteriia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
HKD3_k127_6393704_2	760192.Halhy_5376	4.422e-317	989.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HKD3_k127_6393704_9	760192.Halhy_5377	1.091e-179	569.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1INYF@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_6393704_49	365044.Pnap_3713	5.189e-09	67.0	2EP80@1|root,33GUP@2|Bacteria,1NGAM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6393704_33	1123277.KB893175_gene1403	1.578e-58	208.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,47PPX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
HKD3_k127_6393704_24	1122176.KB903554_gene3895	1.519e-73	264.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	BatD,TPR_16,TPR_2,TPR_6,TPR_8
HKD3_k127_6393704_1	760192.Halhy_5639	0.0	1066.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IQJH@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD3_k127_6393704_25	762903.Pedsa_1965	5.242e-73	254.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1IQ48@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HKD3_k127_6393704_27	1122176.KB903554_gene3898	3.844e-67	236.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1ISMS@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_6393704_41	216432.CA2559_08831	4.873e-30	126.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
HKD3_k127_6393704_12	1122176.KB903619_gene5339	3.174e-166	542.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HKD3_k127_6393704_8	1122176.KB903609_gene5268	9.148e-180	568.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD3_k127_6393704_45	1123057.P872_08865	2.813e-20	102.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,47KM1@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD3_k127_6393704_19	1122176.KB903553_gene3621	7.221e-113	381.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1IXCQ@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
HKD3_k127_6393704_30	1122176.KB903587_gene4398	1.671e-65	231.0	COG3597@1|root,COG3597@2|Bacteria,4NSI8@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,SHOCT
HKD3_k127_6393704_0	760192.Halhy_5215	0.0	1282.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
HKD3_k127_6393704_40	1166018.FAES_4376	8.18e-42	167.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
HKD3_k127_6393704_39	1249975.JQLP01000001_gene3013	7.64e-42	156.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1I2YP@117743|Flavobacteriia,2P6XM@244698|Gillisia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
HKD3_k127_6393704_44	984262.SGRA_2419	5.53e-25	110.0	COG3255@1|root,COG3255@2|Bacteria,4NYB1@976|Bacteroidetes	976|Bacteroidetes	I	Sterol-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
HKD3_k127_6393704_21	760192.Halhy_1571	7.344e-100	334.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1IPT6@117747|Sphingobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HKD3_k127_6393704_22	384765.SIAM614_28891	1.648e-89	313.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	MA20_32345	-	-	ko:K02031,ko:K02032,ko:K10823,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD3_k127_6393704_47	1122176.KB903609_gene5130	1.392e-16	91.0	COG0457@1|root,COG0457@2|Bacteria,4PKDV@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PD40,SPOR,TPR_19
HKD3_k127_6393704_5	1122176.KB903565_gene3321	3.871e-200	659.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_6393704_17	1356852.N008_18570	3.889e-128	416.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_6393704_23	717231.Flexsi_0880	1.77e-89	318.0	COG4907@1|root,COG4907@2|Bacteria,2GF9W@200930|Deferribacteres	200930|Deferribacteres	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
HKD3_k127_6393704_34	717231.Flexsi_0881	4.709e-51	188.0	COG1704@1|root,COG1704@2|Bacteria,2GFE4@200930|Deferribacteres	200930|Deferribacteres	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HKD3_k127_6393704_35	1123277.KB893185_gene2994	1.682e-50	190.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD3_k127_6393704_15	1122176.KB903538_gene1461	1.799e-140	453.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPR9@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HKD3_k127_6393704_46	1120956.JHZK01000043_gene3040	1.737e-18	89.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2UF5Y@28211|Alphaproteobacteria,1JPK4@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
HKD3_k127_6393704_18	760192.Halhy_0347	1.171e-117	382.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD3_k127_6411019_1	1237149.C900_02627	2.985e-29	124.0	2EDHQ@1|root,30K5G@2|Bacteria,4PC44@976|Bacteroidetes,47WSK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6411019_0	760192.Halhy_5636	4.758e-48	177.0	COG1595@1|root,COG1595@2|Bacteria,4NP5U@976|Bacteroidetes,1IS8X@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6422200_0	945713.IALB_1179	9.6e-311	976.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6422200_2	945713.IALB_1178	6.562e-133	446.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
HKD3_k127_6428974_3	457424.BFAG_03237	3.739e-12	66.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,2FMY9@200643|Bacteroidia,4AM1G@815|Bacteroidaceae	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HKD3_k127_6428974_1	1123008.KB905695_gene2619	5.657e-102	344.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,2FMFQ@200643|Bacteroidia,22WB3@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_6428974_0	926562.Oweho_3493	4.693e-148	480.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia,2PAEE@246874|Cryomorphaceae	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
HKD3_k127_6428974_2	319236.JCM19294_1278	9.464e-13	71.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1HXYC@117743|Flavobacteriia,3HJSC@363408|Nonlabens	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD3_k127_6438572_0	869213.JCM21142_72890	5.866e-238	770.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47Y6I@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6438572_1	929703.KE386491_gene1906	6.881e-14	78.0	COG3637@1|root,COG3637@2|Bacteria,4PMHA@976|Bacteroidetes	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6439927_11	926549.KI421517_gene2177	7.049e-59	209.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47ME1@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD3_k127_6439927_7	929556.Solca_1726	2.204e-86	299.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
HKD3_k127_6439927_10	1122176.KB903547_gene1071	1.764e-75	270.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_6439927_15	760192.Halhy_3709	2.793e-34	141.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_6439927_19	76636.JOEC01000001_gene391	9.791e-05	50.0	COG1186@1|root,COG1186@2|Bacteria,2IFEJ@201174|Actinobacteria,4FPCB@85023|Microbacteriaceae	201174|Actinobacteria	J	RF-1 domain	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
HKD3_k127_6439927_3	1189620.AJXL01000030_gene2804	3.176e-142	465.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,1HWV3@117743|Flavobacteriia,2NVNR@237|Flavobacterium	976|Bacteroidetes	C	Na(+)-translocating NADH-quinone reductase subunit A (NQRA)	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
HKD3_k127_6439927_4	1189620.AJXL01000030_gene2805	4.786e-137	445.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia,2NVU4@237|Flavobacterium	976|Bacteroidetes	C	NQR2, RnfD, RnfE family	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
HKD3_k127_6439927_12	1408473.JHXO01000006_gene1164	8.127e-54	201.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,2FMQM@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
HKD3_k127_6439927_6	1121887.AUDK01000023_gene3470	1.903e-89	311.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,1HXGP@117743|Flavobacteriia,2NUW6@237|Flavobacterium	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
HKD3_k127_6439927_8	1453500.AT05_07575	4.077e-82	277.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,1HX59@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
HKD3_k127_6439927_1	1121904.ARBP01000007_gene3116	3.685e-186	589.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD3_k127_6439927_9	761193.Runsl_4664	1.932e-79	276.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,47N34@768503|Cytophagia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD3_k127_6439927_18	1279009.ADICEAN_00626	7.907e-13	70.0	2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,47S69@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6439927_13	760192.Halhy_0183	7.075e-48	176.0	COG0517@1|root,COG0517@2|Bacteria,4PNZH@976|Bacteroidetes,1J0W1@117747|Sphingobacteriia	976|Bacteroidetes	S	signal transduction protein with CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_6439927_2	760192.Halhy_0184	2.152e-175	560.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1IVHN@117747|Sphingobacteriia	976|Bacteroidetes	P	COG1055 Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
HKD3_k127_6439927_5	760192.Halhy_5824	6.01e-122	400.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1IPD6@117747|Sphingobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_6439927_14	925409.KI911562_gene1870	1.207e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6439927_17	1237149.C900_05429	4.545e-13	80.0	28JMY@1|root,2Z9ED@2|Bacteria,4NGSX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6439927_0	700598.Niako_6538	0.0	1007.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_6512206_6	1117318.PRUB_01059	0.0008703	43.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,2Q0HS@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
HKD3_k127_6512206_3	880073.Calab_2890	3.716e-109	365.0	COG3616@1|root,COG3616@2|Bacteria,2NPWK@2323|unclassified Bacteria	2|Bacteria	E	Putative serine dehydratase domain	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
HKD3_k127_6512206_4	1123057.P872_07690	2.634e-38	151.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,47XX2@768503|Cytophagia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD3_k127_6512206_5	1267211.KI669560_gene2191	1.1e-36	145.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1ISW6@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD3_k127_6512206_1	945713.IALB_2618	9.63e-181	577.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD3_k127_6512206_0	760192.Halhy_2450	7.123e-182	589.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_6512206_2	1122176.KB903542_gene418	2.196e-171	551.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IP25@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
HKD3_k127_6524259_1	1123248.KB893317_gene4379	8.675e-99	332.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD3_k127_6524259_0	760192.Halhy_0215	1.08e-102	356.0	COG0076@1|root,COG0076@2|Bacteria,4NJ2F@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15,4.1.2.27	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	M00027,M00100	R00261,R00489,R01682,R02464,R02466,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
HKD3_k127_6558962_6	760192.Halhy_2407	1.589e-40	164.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1ITIR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HKD3_k127_6558962_1	760192.Halhy_3617	1.649e-152	490.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HKD3_k127_6558962_3	760192.Halhy_3618	4.285e-117	405.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PIRV@976|Bacteroidetes,1IZ2E@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Pro_isomerase
HKD3_k127_6558962_0	760192.Halhy_3619	5.965e-252	802.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_6558962_4	1166018.FAES_1696	7.665e-88	302.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,47JBE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD3_k127_6558962_7	760192.Halhy_3792	2.763e-19	91.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1ITZV@117747|Sphingobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD3_k127_6558962_2	760192.Halhy_3794	3.694e-137	444.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HKD3_k127_6558962_5	1122176.KB903557_gene4034	1.133e-46	174.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1IQJK@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HKD3_k127_6583959_2	1122176.KB903565_gene3234	4.221e-227	729.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HKD3_k127_6583959_5	1122176.KB903573_gene4826	5.447e-47	180.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
HKD3_k127_6583959_3	760192.Halhy_2933	1.477e-168	546.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6583959_4	760192.Halhy_2934	1.646e-49	181.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,1J07P@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HKD3_k127_6583959_0	1122176.KB903569_gene3481	2.64e-311	971.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1IQ8E@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
HKD3_k127_6583959_6	1313301.AUGC01000003_gene1910	8.176e-45	168.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
HKD3_k127_6583959_7	760192.Halhy_4054	4.743e-40	156.0	COG4845@1|root,COG4845@2|Bacteria,4NPDG@976|Bacteroidetes,1IS3J@117747|Sphingobacteriia	976|Bacteroidetes	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
HKD3_k127_6583959_9	1124780.ANNU01000017_gene1931	1.967e-30	123.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,47RUP@768503|Cytophagia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD3_k127_6583959_10	1168034.FH5T_20345	1.013e-20	100.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6583959_1	485918.Cpin_2039	1.58e-234	732.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1IQTE@117747|Sphingobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
HKD3_k127_6583959_8	1123278.KB893570_gene2443	3.325e-36	142.0	COG0251@1|root,COG0251@2|Bacteria,4NU67@976|Bacteroidetes,47RE6@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HKD3_k127_6583959_11	1122179.KB890439_gene1609	2.339e-07	57.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_C
HKD3_k127_6621234_8	768706.Desor_3625	0.0002356	43.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HKD3_k127_6621234_6	1123248.KB893318_gene4224	4.648e-33	131.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1ITTY@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_6621234_1	1122176.KB903540_gene73	7.629e-108	366.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD3_k127_6621234_2	1122176.KB903540_gene74	3.024e-97	328.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1IQDU@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD3_k127_6621234_3	485918.Cpin_0668	1.992e-71	252.0	COG0300@1|root,COG0300@2|Bacteria,4PM21@976|Bacteroidetes	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_6621234_0	760192.Halhy_2757	1.62e-156	502.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1ISZC@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
HKD3_k127_6621234_4	797209.ZOD2009_12085	2.088e-68	239.0	COG1926@1|root,arCOG06847@2157|Archaea,2XWRW@28890|Euryarchaeota,23V9R@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	DLH
HKD3_k127_6621234_5	1123057.P872_07670	5.809e-58	210.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,47R4U@768503|Cytophagia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
HKD3_k127_6621234_7	240292.Ava_4420	1.099e-28	122.0	COG1514@1|root,COG1514@2|Bacteria,1G5W8@1117|Cyanobacteria,1HN3H@1161|Nostocales	1117|Cyanobacteria	J	2'-5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_6623811_1	1121104.AQXH01000004_gene69	5.897e-149	473.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1IQZ2@117747|Sphingobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
HKD3_k127_6623811_7	1550091.JROE01000008_gene3588	1.22e-47	173.0	COG0346@1|root,COG0346@2|Bacteria,4NQRN@976|Bacteroidetes,1IT4T@117747|Sphingobacteriia	976|Bacteroidetes	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
HKD3_k127_6623811_5	314292.VAS14_15469	6.531e-86	292.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1XXNV@135623|Vibrionales	135623|Vibrionales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD3_k127_6623811_11	1122179.KB890423_gene2316	4.727e-12	74.0	COG3291@1|root,COG3291@2|Bacteria,4PHZU@976|Bacteroidetes,1IWHN@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_6623811_2	1121904.ARBP01000015_gene214	2.768e-105	346.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Glycos_transf_2,HTH_20,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
HKD3_k127_6623811_3	1121481.AUAS01000009_gene3	2.665e-100	342.0	COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,47NQE@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294,ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_6623811_4	742727.HMPREF9447_05298	2.286e-99	340.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,2FR8R@200643|Bacteroidia,4AQA2@815|Bacteroidaceae	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_6623811_0	1492737.FEM08_18800	2.214e-151	492.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia,2NTT8@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
HKD3_k127_6623811_8	929713.NIASO_11070	1.884e-33	132.0	2CFT1@1|root,32S2F@2|Bacteria,4NTM5@976|Bacteroidetes,1IYHT@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6623811_10	1121896.JMLU01000027_gene576	2.76e-22	106.0	COG1566@1|root,COG1566@2|Bacteria,4PKRC@976|Bacteroidetes,1IJDD@117743|Flavobacteriia,2NS5Y@237|Flavobacterium	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
HKD3_k127_6623811_6	504472.Slin_2355	1.906e-72	254.0	COG0745@1|root,COG0745@2|Bacteria,4NIKR@976|Bacteroidetes,47PEG@768503|Cytophagia	976|Bacteroidetes	KT	transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HKD3_k127_6623811_9	760192.Halhy_1074	1.614e-29	130.0	COG4447@1|root,COG4447@2|Bacteria,4NHFZ@976|Bacteroidetes,1IRR7@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
HKD3_k127_6636163_6	1121904.ARBP01000009_gene4235	3.378e-08	64.0	2E3RZ@1|root,32YPK@2|Bacteria,4NVPS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6636163_3	1267533.KB906736_gene1284	1.995e-43	175.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
HKD3_k127_6636163_2	700598.Niako_0657	2.658e-79	298.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NK65@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Reg_prop
HKD3_k127_6636163_4	700598.Niako_0658	7.656e-32	133.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_6636163_0	247490.KSU1_C1442	2.331e-241	759.0	COG3119@1|root,COG3119@2|Bacteria,2IXNZ@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
HKD3_k127_6636163_1	1453500.AT05_10945	6.077e-90	304.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_6660284_2	531844.FIC_00879	2.45e-86	292.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1HYTR@117743|Flavobacteriia,4061Q@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Semialdehyde dehydrogenase, NAD binding domain	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_6660284_1	531844.FIC_00878	3.074e-189	597.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1HZAN@117743|Flavobacteriia,405ZC@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD3_k127_6660284_3	531844.FIC_00877	5.409e-84	283.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IJGE@117743|Flavobacteriia,406A5@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_6660284_0	760192.Halhy_4972	1.388e-193	612.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1IPI2@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_6660284_4	118163.Ple7327_0294	2.79e-79	269.0	COG3752@1|root,COG3752@2|Bacteria,1G0MQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
HKD3_k127_6723972_2	383372.Rcas_2462	3.416e-06	57.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
HKD3_k127_6723972_1	1288963.ADIS_4862	1.276e-12	76.0	COG1426@1|root,COG1426@2|Bacteria,4PMNR@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD3_k127_6723972_0	1122176.KB903549_gene1285	5.351e-312	973.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1INYW@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HKD3_k127_6739379_6	385682.AFSL01000025_gene2104	5.737e-51	190.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,2FV24@200643|Bacteroidia,3XKFT@558415|Marinilabiliaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD3_k127_6739379_11	435908.IDSA_07890	2.656e-17	82.0	2ENDF@1|root,33G0X@2|Bacteria,1P621@1224|Proteobacteria,1SV8Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6739379_10	153721.MYP_1225	2.346e-18	90.0	COG2827@1|root,COG2827@2|Bacteria,4NZEA@976|Bacteroidetes	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
HKD3_k127_6739379_5	313603.FB2170_17346	1.201e-61	220.0	COG0652@1|root,COG0652@2|Bacteria,4NQYP@976|Bacteroidetes,1I3H5@117743|Flavobacteriia	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
HKD3_k127_6739379_2	760192.Halhy_0001	1.278e-178	570.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1INXF@117747|Sphingobacteriia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD3_k127_6739379_3	984262.SGRA_4226	1.809e-101	344.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IQB8@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD3_k127_6739379_8	1122176.KB903587_gene4377	1.304e-43	173.0	COG0737@1|root,COG0737@2|Bacteria,4NR6D@976|Bacteroidetes,1ITBW@117747|Sphingobacteriia	976|Bacteroidetes	F	5'-nucleotidase	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
HKD3_k127_6739379_9	1122176.KB903619_gene5434	3.616e-20	102.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1ITU0@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6739379_7	760192.Halhy_6023	3.879e-49	177.0	COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,1ISU6@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD3_k127_6739379_0	643867.Ftrac_3280	7.811e-187	593.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_6739379_1	1124780.ANNU01000072_gene1055	5.566e-185	601.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_6739379_4	1122176.KB903554_gene3936	2.034e-75	259.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD3_k127_6750974_9	742766.HMPREF9455_03747	1.314e-36	141.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,2FU2H@200643|Bacteroidia,22YGZ@171551|Porphyromonadaceae	976|Bacteroidetes	S	tigr02436	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_6750974_0	760192.Halhy_1461	0.0	1455.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD3_k127_6750974_8	1178825.ALIH01000020_gene2720	6.139e-39	151.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
HKD3_k127_6750974_6	641524.ADICYQ_2562	1.091e-74	258.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,47Y1N@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_6750974_13	670487.Ocepr_2017	1.958e-12	69.0	COG4877@1|root,COG4877@2|Bacteria,1WKMS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
HKD3_k127_6750974_2	1237149.C900_05303	4.26e-112	368.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia	976|Bacteroidetes	O	membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD3_k127_6750974_7	1122179.KB890468_gene447	5.736e-44	168.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1IPS4@117747|Sphingobacteriia	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HKD3_k127_6750974_10	886293.Sinac_0066	4.86e-36	149.0	COG3921@1|root,COG3921@2|Bacteria,2J1YT@203682|Planctomycetes	203682|Planctomycetes	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
HKD3_k127_6750974_11	1288963.ADIS_3954	3.628e-33	133.0	COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes,47R97@768503|Cytophagia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD3_k127_6750974_3	1288963.ADIS_4464	2.872e-96	323.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JJV@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD3_k127_6750974_5	1122176.KB903544_gene709	3.492e-77	275.0	COG0438@1|root,COG0438@2|Bacteria,4NVTH@976|Bacteroidetes,1J1AJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_6750974_1	1237149.C900_01015	2.345e-187	616.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_6750974_4	760192.Halhy_4124	6.401e-82	276.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1IRSU@117747|Sphingobacteriia	976|Bacteroidetes	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD3_k127_676192_4	1121904.ARBP01000009_gene4389	3.092e-41	159.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47JAV@768503|Cytophagia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_676192_2	1313421.JHBV01000021_gene4813	7.929e-84	289.0	COG0604@1|root,COG0604@2|Bacteria,4NPBM@976|Bacteroidetes,1ITI8@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD3_k127_676192_0	760192.Halhy_4150	2.134e-245	787.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,1IR4H@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HKD3_k127_676192_3	1288963.ADIS_3567	4.316e-46	169.0	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,47PW5@768503|Cytophagia	976|Bacteroidetes	G	MGS-like domain	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HKD3_k127_676192_1	760192.Halhy_2136	1.99e-220	700.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1IPMR@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD3_k127_6763774_2	1313421.JHBV01000004_gene774	7.206e-33	139.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IYET@117747|Sphingobacteriia	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HKD3_k127_6763774_1	984262.SGRA_2055	3.329e-85	295.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1ISH9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall hydrolase autolysin	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD3_k127_6763774_0	760192.Halhy_0308	8.079e-127	424.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6783499_1	313596.RB2501_13264	2.912e-28	115.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HKD3_k127_6783499_2	1034807.FBFL15_1058	1.251e-09	68.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,2NWCZ@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_6783499_0	313606.M23134_05335	2.453e-127	439.0	COG1372@1|root,COG4447@1|root,COG5184@1|root,COG5492@1|root,COG1372@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
HKD3_k127_6794297_0	1122179.KB890413_gene4885	6.223e-96	321.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1IQ8J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_6794297_1	1121897.AUGO01000006_gene779	1.466e-53	198.0	COG1345@1|root,COG2374@1|root,COG2911@1|root,COG4447@1|root,COG1345@2|Bacteria,COG2374@2|Bacteria,COG2911@2|Bacteria,COG4447@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia,2P0S4@237|Flavobacterium	976|Bacteroidetes	N	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
HKD3_k127_6840212_2	760192.Halhy_4248	2.769e-63	225.0	2DBMF@1|root,2Z9YG@2|Bacteria,4NPWU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6840212_1	1121890.AUDO01000003_gene1814	6.127e-77	264.0	2AEQA@1|root,314KU@2|Bacteria,4PJ85@976|Bacteroidetes,1ICT3@117743|Flavobacteriia,2NUK1@237|Flavobacterium	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
HKD3_k127_6840212_3	1185876.BN8_01713	1.113e-30	131.0	COG0454@1|root,COG0662@1|root,COG0456@2|Bacteria,COG0662@2|Bacteria,4NTZN@976|Bacteroidetes,47RG8@768503|Cytophagia	976|Bacteroidetes	G	ARD/ARD' family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_6840212_0	1122621.ATZA01000083_gene2796	1.688e-227	712.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD3_k127_6840212_4	639030.JHVA01000001_gene3726	8.143e-09	64.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria,2JM74@204432|Acidobacteriia	204432|Acidobacteriia	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_6,TPR_8
HKD3_k127_6901858_7	1122176.KB903565_gene3244	9.853e-07	51.0	COG1629@1|root,COG1629@2|Bacteria,4PPDE@976|Bacteroidetes,1IYC1@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_6901858_0	760192.Halhy_4034	0.0	1306.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1J03H@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6901858_1	760192.Halhy_4035	1.04e-112	374.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1IYUI@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_6901858_3	1122176.KB903565_gene3247	8.522e-60	211.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1IS01@117747|Sphingobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD3_k127_6901858_4	1121097.JCM15093_2413	2.513e-49	178.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia,4AQKH@815|Bacteroidaceae	976|Bacteroidetes	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HKD3_k127_6901858_9	118173.KB235914_gene2659	0.0003288	48.0	29K36@1|root,3070J@2|Bacteria,1G63U@1117|Cyanobacteria,1HGII@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6901858_8	1229487.AMYW01000001_gene4079	7.199e-06	51.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6901858_5	760192.Halhy_2563	2.933e-16	89.0	COG3228@1|root,COG3228@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
HKD3_k127_6901858_2	760192.Halhy_2762	9.293e-65	232.0	COG4319@1|root,COG4319@2|Bacteria,4PP1J@976|Bacteroidetes,1J0X2@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
HKD3_k127_6901858_6	1270193.JARP01000002_gene349	4.649e-08	61.0	COG1345@1|root,COG3405@1|root,COG1345@2|Bacteria,COG3405@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3
HKD3_k127_7072015_2	984262.SGRA_1175	1.699e-104	355.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
HKD3_k127_7072015_0	760192.Halhy_2005	3.058e-121	405.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1IQ8A@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
HKD3_k127_7072015_3	1122176.KB903534_gene2150	2.736e-104	353.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1IPXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_7072015_1	1122176.KB903543_gene613	2.916e-118	394.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IR5G@117747|Sphingobacteriia	976|Bacteroidetes	KT	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
HKD3_k127_7072015_7	760192.Halhy_3172	9.658e-62	222.0	COG0457@1|root,COG2314@1|root,COG0457@2|Bacteria,COG2314@2|Bacteria,4NW91@976|Bacteroidetes	976|Bacteroidetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,TM2,TPR_11
HKD3_k127_7072015_6	760192.Halhy_3171	2.619e-67	235.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1IRUD@117747|Sphingobacteriia	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_7072015_4	1122176.KB903542_gene337	1.081e-83	297.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,1IWQ4@117747|Sphingobacteriia	976|Bacteroidetes	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD3_k127_7072015_5	760192.Halhy_2991	1.801e-76	265.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1IP1D@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_7154497_4	946362.XP_004997743.1	8.551e-153	521.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD3_k127_7154497_3	1358423.N180_12035	1.947e-169	548.0	COG3637@1|root,COG3637@2|Bacteria,4PM31@976|Bacteroidetes	976|Bacteroidetes	M	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
HKD3_k127_7154497_0	1358423.N180_12040	0.0	1132.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1J0RM@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7154497_11	700598.Niako_5598	1.819e-19	89.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IUFV@117747|Sphingobacteriia	976|Bacteroidetes	U	Sec-independent protein translocase protein TatA	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HKD3_k127_7154497_12	926549.KI421517_gene1336	8.104e-17	87.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,47VW2@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_7154497_8	1453500.AT05_05675	1.066e-60	223.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,4NK8R@976|Bacteroidetes,1I0Y1@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
HKD3_k127_7154497_1	1313421.JHBV01000022_gene4644	5.151e-187	602.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_7154497_10	1313301.AUGC01000001_gene1471	1.326e-24	106.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
HKD3_k127_7154497_6	1122176.KB903565_gene3230	1.942e-83	287.0	COG1121@1|root,COG1121@2|Bacteria,4NHZ9@976|Bacteroidetes,1J083@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPases associated with a variety of cellular activities	troB	-	3.6.3.35	ko:K11710,ko:K19973	ko02010,map02010	M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
HKD3_k127_7154497_5	1122176.KB903565_gene3229	2.203e-94	319.0	COG0803@1|root,COG0803@2|Bacteria,4NGMC@976|Bacteroidetes,1IYDH@117747|Sphingobacteriia	976|Bacteroidetes	P	Zinc-uptake complex component A periplasmic	mntA	-	-	ko:K09815,ko:K11707	ko02010,map02010	M00242,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HKD3_k127_7154497_7	471854.Dfer_4678	7.119e-65	228.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD3_k127_7154497_2	927658.AJUM01000024_gene2518	3.352e-186	593.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,2FMUY@200643|Bacteroidia,3XIQI@558415|Marinilabiliaceae	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
HKD3_k127_7154497_9	714943.Mucpa_4531	1.173e-35	136.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INWZ@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase S9 prolyl oligopeptidase active site domain protein	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD3_k127_7165530_17	1123278.KB893411_gene2872	4.548e-22	112.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
HKD3_k127_7165530_13	1123326.JFBL01000023_gene2544	6.702e-47	179.0	COG1741@1|root,COG1741@2|Bacteria	2|Bacteria	O	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HKD3_k127_7165530_18	1121957.ATVL01000006_gene2595	1.681e-16	83.0	COG2010@1|root,COG2010@2|Bacteria,4NSUK@976|Bacteroidetes,47R5S@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,SirB
HKD3_k127_7165530_9	1122179.KB890425_gene3375	1.454e-69	249.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1IWIT@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
HKD3_k127_7165530_12	760192.Halhy_2290	3.957e-52	197.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1IQ5S@117747|Sphingobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
HKD3_k127_7165530_6	742767.HMPREF9456_02018	3.4e-79	284.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,2FM5V@200643|Bacteroidia,22VZV@171551|Porphyromonadaceae	976|Bacteroidetes	M	transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
HKD3_k127_7165530_0	1122176.KB903548_gene1169	1.169e-317	983.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HKD3_k127_7165530_7	1267211.KI669560_gene2254	1.207e-72	271.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
HKD3_k127_7165530_2	504472.Slin_2522	2.379e-195	629.0	COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,47M96@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
HKD3_k127_7165530_3	984262.SGRA_4096	7.819e-172	557.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1IQYY@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD3_k127_7165530_8	869213.JCM21142_31174	8.786e-71	245.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,47P7V@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
HKD3_k127_7165530_14	760192.Halhy_4461	8.66e-43	163.0	2EV05@1|root,33NFB@2|Bacteria,4NXZZ@976|Bacteroidetes,1IZZX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7165530_11	1122179.KB890414_gene1740	6.428e-57	202.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1ISDN@117747|Sphingobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
HKD3_k127_7165530_1	1122179.KB890434_gene850	9.625e-219	688.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1IPBW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HKD3_k127_7165530_10	421531.IX38_18465	2.002e-64	226.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1I1TP@117743|Flavobacteriia,3ZQNN@59732|Chryseobacterium	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD3_k127_7165530_15	761193.Runsl_2509	1.16e-41	160.0	COG1943@1|root,COG1943@2|Bacteria,4NPUC@976|Bacteroidetes,47Q09@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD3_k127_7165530_4	760192.Halhy_1267	2.212e-91	317.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1INW8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
HKD3_k127_7165530_5	760192.Halhy_1268	2.697e-91	319.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IP2E@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HKD3_k127_7165530_16	760192.Halhy_1269	6.737e-24	104.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1IRGW@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
HKD3_k127_7269017_9	760192.Halhy_1504	1.256e-20	96.0	2AVDM@1|root,33IZ7@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
HKD3_k127_7269017_4	1121898.Q766_20400	2.944e-86	299.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia,2NT6F@237|Flavobacterium	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
HKD3_k127_7269017_2	760192.Halhy_1506	2.018e-134	452.0	COG1452@1|root,COG1934@1|root,COG1452@2|Bacteria,COG1934@2|Bacteria,4NDU3@976|Bacteroidetes,1IP5G@117747|Sphingobacteriia	976|Bacteroidetes	M	OstA-like protein	lptD	-	-	-	-	-	-	-	-	-	-	-	OstA_2
HKD3_k127_7269017_6	984262.SGRA_3800	2.649e-70	248.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1IRY5@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HKD3_k127_7269017_8	1122176.KB903609_gene5243	4.214e-39	147.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,1ITH1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
HKD3_k127_7269017_1	760192.Halhy_0165	5.27e-174	552.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1INNG@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD3_k127_7269017_3	760192.Halhy_0166	5.73e-128	421.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1IR94@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_7269017_7	760192.Halhy_5157	3.374e-45	166.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1ISA4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD3_k127_7269017_10	760192.Halhy_5158	1.491e-18	86.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1IU0V@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HKD3_k127_7269017_5	1122176.KB903531_gene2877	2.978e-82	277.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1IRGC@117747|Sphingobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HKD3_k127_7269017_0	1122176.KB903531_gene2876	0.0	1285.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD3_k127_7299180_9	760192.Halhy_6212	6.961e-83	282.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1IP7W@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD3_k127_7299180_5	760192.Halhy_6210	1.468e-134	458.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPAI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
HKD3_k127_7299180_0	760192.Halhy_0743	0.0	1139.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
HKD3_k127_7299180_13	1122176.KB903531_gene3067	1.092e-58	209.0	COG2885@1|root,COG2885@2|Bacteria,4P5WM@976|Bacteroidetes	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7299180_12	760192.Halhy_0997	5.221e-60	217.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_7299180_3	1122176.KB903554_gene3940	5.062e-159	505.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD3_k127_7299180_11	1121887.AUDK01000020_gene2371	1.615e-62	229.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia,2NUY4@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HKD3_k127_7299180_7	760192.Halhy_6070	3.056e-120	397.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1IQSA@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
HKD3_k127_7299180_1	926549.KI421517_gene465	5.978e-169	542.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_7299180_8	1313421.JHBV01000011_gene4062	9.573e-104	346.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_7299180_15	984262.SGRA_2825	9.911e-42	160.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,1ISBW@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
HKD3_k127_7299180_14	926562.Oweho_1060	8.472e-52	192.0	COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,1IJP8@117743|Flavobacteriia,2PB5D@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
HKD3_k127_7299180_4	1122176.KB903531_gene2978	1.086e-143	462.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD3_k127_7299180_10	1358423.N180_11360	3.549e-80	280.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1IP1J@117747|Sphingobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
HKD3_k127_7299180_17	1122605.KB893625_gene2230	6.699e-08	59.0	COG5512@1|root,COG5512@2|Bacteria,4P9X5@976|Bacteroidetes,1IUES@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
HKD3_k127_7299180_6	760192.Halhy_5744	3.939e-134	462.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1INME@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_7299180_16	1313421.JHBV01000043_gene3004	3.248e-27	123.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,1J0BI@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_7299180_2	1122176.KB903619_gene5416	1.836e-167	551.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
HKD3_k127_7311446_3	269798.CHU_1374	1.891e-15	80.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,47KWS@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
HKD3_k127_7311446_2	1121373.KB903623_gene2358	1.2e-145	470.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47K9J@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HKD3_k127_7311446_0	714943.Mucpa_3124	1.036e-157	502.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
HKD3_k127_7311446_1	1270196.JCKI01000001_gene3976	1.294e-147	471.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HKD3_k127_7315779_0	471854.Dfer_1503	1.271e-104	367.0	COG1956@1|root,COG2972@1|root,COG3292@1|root,COG1956@2|Bacteria,COG2972@2|Bacteria,COG3292@2|Bacteria,4NHMQ@976|Bacteroidetes,47P3A@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_7315779_1	1121481.AUAS01000018_gene477	3.926e-60	229.0	COG3279@1|root,COG3279@2|Bacteria,4NK6R@976|Bacteroidetes,47XDW@768503|Cytophagia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_7315779_2	1123277.KB893243_gene135	2.394e-16	87.0	2EDR9@1|root,33BZ6@2|Bacteria,4NYGY@976|Bacteroidetes,47VFV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7322076_3	1166018.FAES_3181	1.182e-61	233.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
HKD3_k127_7322076_6	760192.Halhy_4503	1.272e-45	179.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
HKD3_k127_7322076_4	1122176.KB903543_gene636	8.609e-61	220.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
HKD3_k127_7322076_10	760192.Halhy_5013	1.58e-09	66.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
HKD3_k127_7322076_2	1122176.KB903535_gene1889	1.463e-94	323.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_7322076_7	760192.Halhy_2956	1.181e-40	166.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7322076_1	1122176.KB903534_gene2154	2.234e-115	387.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1IVGY@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_7322076_5	1122176.KB903534_gene2153	6.708e-47	174.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ISJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_7322076_8	1392489.JPOL01000002_gene2858	3.704e-33	140.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1I2T1@117743|Flavobacteriia,2XJDJ@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
HKD3_k127_7322076_0	760192.Halhy_3783	3.63e-241	758.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_7322076_9	1408433.JHXV01000007_gene2827	8.71e-31	128.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,4PFHG@976|Bacteroidetes,1IG76@117743|Flavobacteriia,2PBAN@246874|Cryomorphaceae	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
HKD3_k127_7352566_0	331869.BAL199_01069	6.912e-91	311.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,4BRPC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD3_k127_7352566_2	932213.SPM24T3_03567	2.119e-16	93.0	COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,1RY6Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates	amiE	GO:0003674,GO:0003824,GO:0004040,GO:0016787,GO:0016810,GO:0016811	3.5.1.4,3.5.1.49	ko:K01426,ko:K01455	ko00330,ko00360,ko00380,ko00460,ko00627,ko00630,ko00643,ko00910,ko01120,ko01200,map00330,map00360,map00380,map00460,map00627,map00630,map00643,map00910,map01120,map01200	-	R00524,R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025,RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HKD3_k127_7352566_1	1379270.AUXF01000002_gene1250	2.266e-38	161.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_7373837_16	760192.Halhy_2681	3.351e-28	118.0	COG0517@1|root,COG0517@2|Bacteria,4NZCM@976|Bacteroidetes	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_7373837_8	1150600.ADIARSV_3542	1.322e-108	364.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	lysDH	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
HKD3_k127_7373837_0	760192.Halhy_1857	1.66e-292	922.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HKD3_k127_7373837_18	760192.Halhy_1704	8.029e-16	89.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1ISAH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
HKD3_k127_7373837_2	1122179.KB890420_gene2447	5.541e-206	654.0	COG0318@1|root,COG0318@2|Bacteria,4NDYR@976|Bacteroidetes,1J0MB@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_7373837_10	1122176.KB903542_gene393	9.946e-71	248.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
HKD3_k127_7373837_15	1122176.KB903542_gene394	5.967e-32	132.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1ISVJ@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
HKD3_k127_7373837_6	760192.Halhy_2725	8.824e-141	458.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1IPJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD3_k127_7373837_11	760192.Halhy_2724	1.692e-63	229.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
HKD3_k127_7373837_12	925409.KI911562_gene1014	8.084e-54	196.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
HKD3_k127_7373837_14	926556.Echvi_0643	1.988e-41	164.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
HKD3_k127_7373837_3	1122176.KB903540_gene128	1.069e-193	622.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1IQ58@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_7373837_1	1122176.KB903540_gene125	9.558e-244	760.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1INM0@117747|Sphingobacteriia	976|Bacteroidetes	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_7373837_13	1122176.KB903540_gene124	1.547e-46	173.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD3_k127_7373837_9	1122176.KB903540_gene123	4.615e-80	271.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD3_k127_7373837_7	1122176.KB903542_gene328	7.48e-138	445.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD3_k127_7373837_5	1501391.LG35_02060	8.44e-146	473.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,2FNW2@200643|Bacteroidia,22V7B@171550|Rikenellaceae	976|Bacteroidetes	F	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_7373837_4	1122176.KB903576_gene4911	2.6e-165	566.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cohesin,DUF11,SprB
HKD3_k127_7379006_3	1158294.JOMI01000003_gene2671	1.169e-69	245.0	COG0600@1|root,COG0600@2|Bacteria,4NPPC@976|Bacteroidetes	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15577	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	BPD_transp_1
HKD3_k127_7379006_1	1317122.ATO12_16475	5.121e-139	458.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,4NM1E@976|Bacteroidetes,1IAUW@117743|Flavobacteriia,2YK6M@290174|Aquimarina	976|Bacteroidetes	MP	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,OmpA
HKD3_k127_7379006_2	1122176.KB903554_gene3841	1.741e-127	417.0	COG1842@1|root,COG1842@2|Bacteria,4NIZP@976|Bacteroidetes,1IZFV@117747|Sphingobacteriia	976|Bacteroidetes	KT	Phage shock protein A	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7379006_5	929562.Emtol_0719	9.212e-40	156.0	28MN0@1|root,2ZAXM@2|Bacteria,4NKT3@976|Bacteroidetes,47NBY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7379006_0	760192.Halhy_0800	7.434e-168	538.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,1IP21@117747|Sphingobacteriia	976|Bacteroidetes	E	Arginine deiminase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
HKD3_k127_7379006_4	1122176.KB903538_gene1521	2.514e-41	158.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IT5E@117747|Sphingobacteriia	976|Bacteroidetes	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD3_k127_7379006_6	1168034.FH5T_04700	1.661e-08	61.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD3_k127_7381703_3	760192.Halhy_1819	3.262e-96	323.0	COG0378@1|root,COG0378@2|Bacteria,4NJ0P@976|Bacteroidetes,1IR6X@117747|Sphingobacteriia	976|Bacteroidetes	KO	COGs COG0378 Ni2 -binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
HKD3_k127_7381703_0	504472.Slin_3880	1.888e-214	691.0	COG0068@1|root,COG0068@2|Bacteria,4NIZ1@976|Bacteroidetes,47TB5@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM NiFe hydrogenase maturation protein HypF	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
HKD3_k127_7381703_4	317619.ANKN01000101_gene3225	2.944e-11	69.0	COG0298@1|root,COG0298@2|Bacteria,1G9FZ@1117|Cyanobacteria	1117|Cyanobacteria	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
HKD3_k127_7381703_1	504472.Slin_3878	1.263e-165	527.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes,47TQG@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
HKD3_k127_7381703_2	1250232.JQNJ01000001_gene1812	1.781e-117	386.0	COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes,1HZ4R@117743|Flavobacteriia	976|Bacteroidetes	O	AIR synthase related protein, N-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
HKD3_k127_7385990_0	398767.Glov_1066	2.118e-130	439.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HKD3_k127_7385990_2	1122179.KB890416_gene2678	7.286e-25	109.0	COG0477@1|root,COG2814@2|Bacteria,4NUYS@976|Bacteroidetes	976|Bacteroidetes	EGP	TIGRFAM integral membrane protein	ydzA	-	-	-	-	-	-	-	-	-	-	-	DUF3817
HKD3_k127_7385990_1	1185876.BN8_05132	1.118e-97	339.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,47K31@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
HKD3_k127_7385990_3	1122179.KB890458_gene799	5.661e-08	60.0	COG3307@1|root,COG3307@2|Bacteria,4NU0S@976|Bacteroidetes,1IUM4@117747|Sphingobacteriia	976|Bacteroidetes	M	O-antigen ligase like membrane protein	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
HKD3_k127_7387090_1	760192.Halhy_4165	1.83e-59	207.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1INUM@117747|Sphingobacteriia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD3_k127_7387090_2	1122179.KB890491_gene4491	1.444e-58	211.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IST6@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HKD3_k127_7387090_0	1182590.BN5_00822	3.451e-74	257.0	COG0388@1|root,COG0388@2|Bacteria,1MXBR@1224|Proteobacteria,1RQ4Z@1236|Gammaproteobacteria,1YEZV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Carbon-nitrogen hydrolase	yafV	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050152,GO:0071944,GO:0106008	3.5.1.3	ko:K11206,ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HKD3_k127_7387090_3	1313421.JHBV01000016_gene5400	1.161e-28	122.0	COG0791@1|root,COG0791@2|Bacteria,4NUNS@976|Bacteroidetes,1ITXU@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG0791 Cell wall-associated hydrolase (invasion-associated protein)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HKD3_k127_7387090_4	1122179.KB890416_gene2683	6.623e-13	70.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	CP_0991	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD3_k127_7389716_1	760192.Halhy_4808	5.626e-59	212.0	COG0807@1|root,COG0807@2|Bacteria,4PNQF@976|Bacteroidetes,1J0XM@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase II	ribA	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydro2
HKD3_k127_7389716_0	1137281.D778_01222	3.32e-152	497.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD3_k127_7389955_1	1122176.KB903551_gene4205	0.0002416	44.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	fhaB2	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	DUF637,Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN
HKD3_k127_7389955_0	1122176.KB903554_gene3906	3.112e-309	959.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1IP3T@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_7396276_1	929556.Solca_0696	8.331e-160	510.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1IPYB@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_7396276_2	1089547.KB913013_gene1517	1.981e-124	409.0	COG3187@1|root,COG3187@2|Bacteria,4NEY0@976|Bacteroidetes,47K7R@768503|Cytophagia	976|Bacteroidetes	O	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3,META
HKD3_k127_7396276_7	216432.CA2559_00625	1.273e-41	166.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,MAM,Peptidase_M14,fn3
HKD3_k127_7396276_12	649349.Lbys_1048	1.661e-06	55.0	2E017@1|root,32VQH@2|Bacteria,4NZ0I@976|Bacteroidetes,47WSA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7396276_9	1150600.ADIARSV_0736	2.621e-32	134.0	2BVY1@1|root,32QYH@2|Bacteria,4NR2M@976|Bacteroidetes,1IU20@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7396276_0	1299327.I546_0356	3.568e-213	678.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,236DX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_7396276_10	376686.Fjoh_4760	4.617e-13	76.0	COG3187@1|root,COG3187@2|Bacteria,4NJC2@976|Bacteroidetes,1I6QI@117743|Flavobacteriia,2P06J@237|Flavobacterium	976|Bacteroidetes	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
HKD3_k127_7396276_6	468059.AUHA01000003_gene1485	1.94e-43	163.0	2DM8U@1|root,3273Z@2|Bacteria,4NQC2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7396276_8	1235803.C825_00972	9.977e-34	151.0	COG5652@1|root,COG5652@2|Bacteria,4NIE7@976|Bacteroidetes,2FQJV@200643|Bacteroidia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510	4.2.2.7,4.2.2.8	ko:K19051	-	-	-	-	ko00000,ko01000	-	PL21	-	DUF4962,Hepar_II_III
HKD3_k127_7396276_4	1107311.Q767_12690	1.463e-56	208.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes,1IADF@117743|Flavobacteriia,2NX79@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7396276_3	1041826.FCOL_10105	3.445e-115	381.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,1HYYV@117743|Flavobacteriia,2NSPI@237|Flavobacterium	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
HKD3_k127_7396276_5	1492737.FEM08_02130	3.499e-50	186.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes,1HXS9@117743|Flavobacteriia,2NUIH@237|Flavobacterium	976|Bacteroidetes	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_2,TPR_8
HKD3_k127_7401353_0	760192.Halhy_1977	3.168e-297	920.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,1IY44@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_7401353_1	926562.Oweho_0543	4.095e-72	266.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia,2PBN1@246874|Cryomorphaceae	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HNOBA,Reg_prop,Response_reg,TPR_12,Y_Y_Y
HKD3_k127_7412259_2	1250232.JQNJ01000001_gene2254	1.8e-93	318.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1HX1F@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde	aldH	-	1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220	-	R00264,R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD3_k127_7412259_1	1185876.BN8_05502	5.724e-112	371.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,47MUZ@768503|Cytophagia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_7412259_5	1122176.KB903532_gene2583	3.857e-39	153.0	COG4430@1|root,COG4430@2|Bacteria,4NW07@976|Bacteroidetes,1IYY0@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
HKD3_k127_7412259_4	1231391.AMZF01000026_gene198	3.892e-44	170.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VSZY@28216|Betaproteobacteria,3T3K6@506|Alcaligenaceae	28216|Betaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD3_k127_7412259_0	1122176.KB903550_gene4288	9.605e-116	380.0	28J46@1|root,2Z906@2|Bacteria,4NFYM@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
HKD3_k127_7412259_3	411154.GFO_0032	2.933e-63	227.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,1I0YN@117743|Flavobacteriia	976|Bacteroidetes	G	Arabinogalactan endo-beta-1,4-galactanase	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
HKD3_k127_7420536_2	313590.MED134_01845	2.769e-88	297.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia,37EP3@326319|Dokdonia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
HKD3_k127_7420536_1	1121904.ARBP01000006_gene3733	2.235e-205	663.0	COG1297@1|root,COG1297@2|Bacteria,4NEIY@976|Bacteroidetes,47KFV@768503|Cytophagia	976|Bacteroidetes	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HKD3_k127_7420536_5	1121896.JMLU01000048_gene2909	1.769e-12	74.0	COG3212@1|root,COG3212@2|Bacteria,4P9DA@976|Bacteroidetes,1IEN1@117743|Flavobacteriia,2NY22@237|Flavobacterium	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
HKD3_k127_7420536_3	1122176.KB903540_gene17	1.897e-82	297.0	2BV6Z@1|root,32QKE@2|Bacteria,4PCAH@976|Bacteroidetes,1IZE7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7420536_0	1313421.JHBV01000009_gene4118	1.821e-218	691.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
HKD3_k127_7420536_4	760192.Halhy_3220	4.135e-70	242.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1IS18@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD3_k127_7420536_6	1250006.JHZZ01000001_gene1213	8.379e-12	72.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1ICCS@117743|Flavobacteriia,3VWV1@52959|Polaribacter	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_7451539_6	1122176.KB903550_gene4339	2.506e-42	162.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_7451539_1	760192.Halhy_3557	7.995e-175	553.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1IPMZ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD3_k127_7451539_4	1408473.JHXO01000011_gene2963	3.295e-48	183.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HKD3_k127_7451539_7	1122176.KB903550_gene4336	2.278e-23	113.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7451539_0	984262.SGRA_0418	4.775e-179	583.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD3_k127_7451539_5	1122176.KB903550_gene4334	8.766e-47	175.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISG3@117747|Sphingobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
HKD3_k127_7451539_2	1122176.KB903560_gene3540	1.418e-99	340.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
HKD3_k127_7451539_3	929562.Emtol_4258	3.184e-53	198.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,47N0M@768503|Cytophagia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HKD3_k127_7451539_8	402612.FP0543	2.376e-16	81.0	COG0848@1|root,COG0848@2|Bacteria,4NRG7@976|Bacteroidetes,1I3UT@117743|Flavobacteriia,2NVYS@237|Flavobacterium	976|Bacteroidetes	U	Biopolymer transporter ExbD	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
HKD3_k127_7453173_20	760192.Halhy_4565	4.281e-55	200.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1IP2Y@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_7453173_26	1122176.KB903532_gene2546	3.722e-28	116.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1ITNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
HKD3_k127_7453173_31	1410608.JNKX01000016_gene2518	9.817e-08	57.0	2BV3U@1|root,32QGX@2|Bacteria,4PC67@976|Bacteroidetes,2G01C@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7453173_4	760192.Halhy_4567	6.887e-225	700.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1IPDP@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HKD3_k127_7453173_29	1122176.KB903532_gene2543	2.679e-13	71.0	COG0690@1|root,COG0690@2|Bacteria,4PGJJ@976|Bacteroidetes,1ITUV@117747|Sphingobacteriia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HKD3_k127_7453173_11	1122176.KB903532_gene2542	5.54e-88	297.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1INR8@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HKD3_k127_7453173_14	1406840.Q763_14610	3.291e-68	235.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1I18G@117743|Flavobacteriia,2NSUS@237|Flavobacterium	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HKD3_k127_7453173_9	1122176.KB903532_gene2540	1.168e-104	344.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1IPE4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HKD3_k127_7453173_21	760192.Halhy_4572	2.553e-54	195.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1IS1J@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HKD3_k127_7453173_22	926551.KB900739_gene72	1.999e-47	173.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia,1ERZD@1016|Capnocytophaga	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HKD3_k127_7453173_1	760192.Halhy_4574	0.0	2170.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1INW0@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HKD3_k127_7453173_0	760192.Halhy_4575	0.0	2183.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1IP5J@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HKD3_k127_7453173_19	1122176.KB903545_gene837	5.969e-61	216.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1IPZJ@117747|Sphingobacteriia	976|Bacteroidetes	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HKD3_k127_7453173_3	760192.Halhy_4460	8.626e-246	787.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD3_k127_7453173_15	760192.Halhy_1294	7.639e-68	242.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IP3S@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD3_k127_7453173_18	984262.SGRA_0903	1.235e-62	220.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1IRUX@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
HKD3_k127_7453173_6	1122176.KB903576_gene4986	1.121e-189	600.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1IR18@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HKD3_k127_7453173_10	1122176.KB903535_gene1959	4.844e-102	342.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1INM6@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD3_k127_7453173_16	929556.Solca_3194	1.902e-64	228.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7453173_27	1122176.KB903532_gene2679	2.706e-27	119.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1ISIF@117747|Sphingobacteriia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
HKD3_k127_7453173_12	743722.Sph21_3393	3.19e-75	262.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1INVP@117747|Sphingobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_7453173_23	926562.Oweho_1158	4.729e-39	150.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1I450@117743|Flavobacteriia,2PB6E@246874|Cryomorphaceae	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
HKD3_k127_7453173_13	1197477.IA57_06930	2.13e-73	261.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
HKD3_k127_7453173_8	1122176.KB903554_gene3866	5.711e-106	357.0	COG0860@1|root,COG0860@2|Bacteria,4NHZA@976|Bacteroidetes	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD3_k127_7453173_24	1122176.KB903554_gene3867	4.59e-37	149.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,1IP2M@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
HKD3_k127_7453173_7	760192.Halhy_6299	7.986e-110	366.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,1INSK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
HKD3_k127_7453173_32	1227739.Hsw_0476	2.071e-06	59.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes,47SN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7453173_5	1313421.JHBV01000035_gene2524	2.113e-210	662.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD3_k127_7453173_17	760192.Halhy_6302	1.948e-63	222.0	COG1522@1|root,COG1522@2|Bacteria,4NMYA@976|Bacteroidetes,1IS24@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, asnc family	-	-	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
HKD3_k127_7453173_25	760192.Halhy_6303	2.135e-33	139.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes	976|Bacteroidetes	S	GumN protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
HKD3_k127_7453173_2	1122176.KB903531_gene2890	1.452e-276	867.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7485735_14	760192.Halhy_2027	1.499e-53	192.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HKD3_k127_7485735_8	485918.Cpin_6241	3.521e-127	441.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,1IQHQ@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7485735_9	760192.Halhy_2028	2.228e-88	300.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
HKD3_k127_7485735_11	313596.RB2501_08660	9.262e-82	278.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1HXDH@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_7485735_4	984262.SGRA_2716	9.315e-180	576.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD3_k127_7485735_10	984262.SGRA_1777	1.858e-85	314.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1ITGA@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_7485735_3	1122179.KB890425_gene3353	2.63e-228	718.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD3_k127_7485735_6	1122179.KB890458_gene817	6.768e-168	542.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_7485735_13	1313421.JHBV01000042_gene3264	6.979e-56	199.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD3_k127_7485735_0	760192.Halhy_2125	0.0	1188.0	COG0730@1|root,COG0730@2|Bacteria,4PP1E@976|Bacteroidetes,1J0WY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
HKD3_k127_7485735_16	385682.AFSL01000090_gene943	5.027e-09	61.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,2FYHY@200643|Bacteroidia,3XKCD@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD3_k127_7485735_15	1313421.JHBV01000029_gene2009	6.644e-42	169.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
HKD3_k127_7485735_12	1121129.KB903359_gene2323	5.396e-75	258.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,22WJC@171551|Porphyromonadaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD3_k127_7485735_5	616991.JPOO01000003_gene1238	4.854e-178	570.0	COG2931@1|root,COG2931@2|Bacteria,4PKJU@976|Bacteroidetes,1IJB7@117743|Flavobacteriia,23H57@178469|Arenibacter	976|Bacteroidetes	Q	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_7485735_1	761193.Runsl_4914	6.745e-315	974.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,4NG9R@976|Bacteroidetes,47KDW@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
HKD3_k127_7485735_2	1288963.ADIS_2622	1.293e-274	856.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,47KM5@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
HKD3_k127_7485735_7	1279009.ADICEAN_01742	3.031e-141	454.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD3_k127_7502108_2	1122176.KB903536_gene1761	3.033e-81	279.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7502108_1	1279009.ADICEAN_01896	1.929e-94	321.0	COG2010@1|root,COG2010@2|Bacteria,4NMWQ@976|Bacteroidetes,47XQB@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
HKD3_k127_7502108_3	742817.HMPREF9449_00795	9.834e-71	254.0	COG0438@1|root,COG0438@2|Bacteria,4PMXT@976|Bacteroidetes,2G0JY@200643|Bacteroidia,231CH@171551|Porphyromonadaceae	976|Bacteroidetes	M	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
HKD3_k127_7502108_0	1249975.JQLP01000005_gene1622	1.003e-109	358.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,1HY91@117743|Flavobacteriia,2P6PK@244698|Gillisia	976|Bacteroidetes	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
HKD3_k127_7516824_1	1122621.ATZA01000006_gene705	5.202e-19	90.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1ISGQ@117747|Sphingobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD3_k127_7516824_0	760192.Halhy_3444	3.548e-286	902.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1IR71@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
HKD3_k127_7527451_9	46234.ANA_C13316	7.947e-15	74.0	COG0614@1|root,COG0614@2|Bacteria,1G79B@1117|Cyanobacteria,1HNFV@1161|Nostocales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
HKD3_k127_7527451_11	468059.AUHA01000007_gene2684	3.811e-07	62.0	COG0589@1|root,COG0589@2|Bacteria,4PICM@976|Bacteroidetes,1IYVE@117747|Sphingobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_7527451_5	760192.Halhy_3122	5.408e-41	163.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
HKD3_k127_7527451_1	760192.Halhy_2679	2.443e-120	400.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,4NG0Y@976|Bacteroidetes,1IPHZ@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
HKD3_k127_7527451_2	1313421.JHBV01000041_gene3683	3.533e-83	289.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1INRY@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
HKD3_k127_7527451_4	1121889.AUDM01000019_gene112	2.324e-46	177.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia,2P08F@237|Flavobacterium	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_7527451_10	641143.HMPREF9331_00274	8.363e-13	78.0	COG0517@1|root,COG0517@2|Bacteria,4NQYH@976|Bacteroidetes,1I24R@117743|Flavobacteriia,1ERTQ@1016|Capnocytophaga	976|Bacteroidetes	S	CBS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_7527451_6	760192.Halhy_2681	9.626e-34	135.0	COG0517@1|root,COG0517@2|Bacteria,4NZCM@976|Bacteroidetes	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_7527451_7	925409.KI911562_gene2533	2.917e-28	119.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD3_k127_7527451_0	1317122.ATO12_09700	4.95e-130	425.0	COG2309@1|root,COG2309@2|Bacteria,4NRU3@976|Bacteroidetes,1IM7P@117743|Flavobacteriia,2YI64@290174|Aquimarina	976|Bacteroidetes	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
HKD3_k127_7527451_3	1122176.KB903542_gene324	3.177e-70	241.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1IR5V@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD3_k127_7536675_1	945713.IALB_0798	1.245e-55	199.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
HKD3_k127_7536675_0	1122176.KB903543_gene572	1.411e-109	364.0	COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,1IPTC@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD3_k127_7547371_0	1185876.BN8_01622	2.198e-220	702.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7547371_3	1095752.HMPREF9969_0935	2.015e-31	136.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,2FMMP@200643|Bacteroidia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
HKD3_k127_7547371_2	288000.BBta_3801	4.237e-39	154.0	COG2242@1|root,COG2242@2|Bacteria,1QW6F@1224|Proteobacteria,2TWPP@28211|Alphaproteobacteria,3JV9N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HKD3_k127_7547371_1	1122176.KB903558_gene4166	6.593e-174	566.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Kelch_1,Malectin,PKD,Peptidase_M6,Peptidase_S8
HKD3_k127_76032_1	925409.KI911562_gene2835	5.242e-193	613.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1IR48@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD3_k127_76032_2	1185876.BN8_05425	1.804e-187	608.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,47MF3@768503|Cytophagia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
HKD3_k127_76032_9	313606.M23134_06910	5.397e-74	255.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
HKD3_k127_76032_16	1279009.ADICEAN_00373	2.9e-52	192.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PPC@768503|Cytophagia	976|Bacteroidetes	O	Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
HKD3_k127_76032_10	1122176.KB903565_gene3223	7.225e-74	269.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1IP2Z@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane protein involved in aromatic hydrocarbon degradation	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
HKD3_k127_76032_20	1122176.KB903565_gene3224	1.336e-21	109.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	3.2.1.8	ko:K01181,ko:K03832	-	-	-	-	ko00000,ko01000,ko02000	2.C.1.1	-	-	DUF2637,TonB_C
HKD3_k127_76032_0	760192.Halhy_2788	7.021e-240	749.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1IQ4M@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HKD3_k127_76032_18	760192.Halhy_3005	2.149e-35	138.0	COG0629@1|root,COG0629@2|Bacteria,4PGRJ@976|Bacteroidetes,1IU5E@117747|Sphingobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
HKD3_k127_76032_19	471854.Dfer_4315	1.453e-25	114.0	2DBYP@1|root,2ZBWI@2|Bacteria,4PPYC@976|Bacteroidetes,47PBE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_76032_14	760192.Halhy_5193	4.35e-55	208.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911,DUF4440,SnoaL_3
HKD3_k127_76032_21	1122176.KB903536_gene1877	6.462e-21	105.0	COG1361@1|root,COG2304@1|root,COG2866@1|root,COG3210@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2866@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	976|Bacteroidetes	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	HYR
HKD3_k127_76032_23	663278.Ethha_0996	1.252e-06	60.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,3WKSE@541000|Ruminococcaceae	186801|Clostridia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
HKD3_k127_76032_8	760192.Halhy_6372	2.047e-75	262.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1INNH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HKD3_k127_76032_25	1500281.JQKZ01000040_gene1351	0.0002068	51.0	COG4319@1|root,COG4319@2|Bacteria,4NQJK@976|Bacteroidetes,1I3PN@117743|Flavobacteriia,3ZRCD@59732|Chryseobacterium	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_76032_13	1122176.KB903538_gene1579	1.192e-56	202.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_76032_5	755732.Fluta_3544	4.038e-94	316.0	COG4122@1|root,COG4122@2|Bacteria,4NJV1@976|Bacteroidetes,1HYRV@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD3_k127_76032_11	1122176.KB903538_gene1512	1.173e-58	231.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
HKD3_k127_76032_22	760192.Halhy_0194	1.01e-12	74.0	COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,1J09E@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	nirK	-	1.7.2.1	ko:K00368,ko:K00405	ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020	M00156,M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3
HKD3_k127_76032_12	760192.Halhy_1863	5.941e-57	205.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1IT0K@117747|Sphingobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD3_k127_76032_24	1185876.BN8_04346	3.51e-05	54.0	2EG8H@1|root,33A0B@2|Bacteria,4NY1M@976|Bacteroidetes,47SNZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_76032_7	679935.Alfi_2853	6.035e-77	263.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,2FKZC@200643|Bacteroidia,22TZJ@171550|Rikenellaceae	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
HKD3_k127_76032_4	1122176.KB903554_gene3947	2.504e-127	421.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IR1Q@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
HKD3_k127_76032_6	1121957.ATVL01000007_gene1748	6.334e-88	304.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,47KVT@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
HKD3_k127_76032_3	760192.Halhy_5567	7.608e-141	459.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HKD3_k127_76032_15	1123276.KB893301_gene4293	1.701e-52	192.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,47V7E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7626399_7	1122931.AUAE01000030_gene867	1.888e-21	97.0	COG0375@1|root,COG0375@2|Bacteria,4NWR5@976|Bacteroidetes,2FV7V@200643|Bacteroidia,22YT9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
HKD3_k127_7626399_1	700598.Niako_1264	2.342e-185	587.0	COG1740@1|root,COG1740@2|Bacteria,4NK1F@976|Bacteroidetes,1IRKT@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1740 Ni Fe-hydrogenase I small subunit	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
HKD3_k127_7626399_0	760192.Halhy_1822	0.0	1007.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1IPFW@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0374 Ni Fe-hydrogenase I large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
HKD3_k127_7626399_3	760192.Halhy_1823	2.529e-100	332.0	COG1969@1|root,COG1969@2|Bacteria,4NIDY@976|Bacteroidetes,1IP16@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1969 Ni Fe-hydrogenase I cytochrome b subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
HKD3_k127_7626399_6	760192.Halhy_1824	2.799e-53	193.0	COG0680@1|root,COG0680@2|Bacteria,4NRQY@976|Bacteroidetes,1IT7D@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0680 Ni Fe-hydrogenase maturation factor	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
HKD3_k127_7626399_4	984262.SGRA_2876	2.15e-56	208.0	COG0668@1|root,COG0668@2|Bacteria,4NNJC@976|Bacteroidetes,1IQZM@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HKD3_k127_7626399_5	216591.BCAL2368	5.184e-56	202.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,1K2M8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_7626399_2	714943.Mucpa_1928	1.267e-119	398.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_7628020_0	1121904.ARBP01000006_gene3699	4.161e-101	338.0	COG3622@1|root,COG3622@2|Bacteria,4PM6P@976|Bacteroidetes,47YPG@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD3_k127_7628020_2	760192.Halhy_2779	2.145e-42	163.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,1ISFV@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
HKD3_k127_7628020_1	984262.SGRA_1195	5.738e-45	169.0	COG3407@1|root,COG3407@2|Bacteria,4NDYX@976|Bacteroidetes	976|Bacteroidetes	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_7657238_1	1408433.JHXV01000032_gene1133	6.036e-13	77.0	COG1807@1|root,COG1807@2|Bacteria,4PG9X@976|Bacteroidetes,1IMRA@117743|Flavobacteriia,2PBNI@246874|Cryomorphaceae	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_7657238_0	1122176.KB903549_gene1260	2.392e-319	987.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1INTV@117747|Sphingobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD3_k127_7660395_3	1197477.IA57_01345	1.888e-05	50.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_7660395_2	760192.Halhy_3345	2.777e-38	157.0	COG3021@1|root,COG3021@2|Bacteria,4PKDH@976|Bacteroidetes,1J0X9@117747|Sphingobacteriia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_7660395_0	1122176.KB903548_gene1186	5.344e-215	677.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1INZ2@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
HKD3_k127_7660395_1	984262.SGRA_2231	1.186e-78	276.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,1IS59@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_7667335_3	1406840.Q763_13035	5.757e-66	246.0	COG1361@1|root,COG3209@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
HKD3_k127_7667335_12	1408433.JHXV01000041_gene3590	2.116e-11	77.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
HKD3_k127_7667335_10	755732.Fluta_0614	2.571e-13	80.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
HKD3_k127_7667335_0	1122176.KB903576_gene4941	1.898e-145	467.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1IPD8@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD3_k127_7667335_7	1122176.KB903576_gene4943	1.374e-28	115.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1IU0P@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD3_k127_7667335_5	760192.Halhy_4817	2.585e-31	126.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1IUBT@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD3_k127_7667335_2	1122176.KB903531_gene3148	1.699e-98	340.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_7667335_11	946077.W5A_09785	8.074e-12	72.0	28MTN@1|root,31GXC@2|Bacteria,4NRCV@976|Bacteroidetes,1I3H7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7667335_13	96561.Dole_1757	1.364e-10	74.0	COG2931@1|root,COG2931@2|Bacteria,1NNT4@1224|Proteobacteria,432A2@68525|delta/epsilon subdivisions,2WXUM@28221|Deltaproteobacteria,2MPG0@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
HKD3_k127_7667335_9	1408433.JHXV01000025_gene4027	3.246e-18	99.0	COG1520@1|root,COG5306@1|root,COG1520@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKHC@117743|Flavobacteriia,2PBKQ@246874|Cryomorphaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
HKD3_k127_7667335_4	471854.Dfer_5770	2.62e-54	197.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47PZB@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
HKD3_k127_7667335_6	1122179.KB890415_gene1969	1.082e-28	126.0	COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,1IZ29@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HKD3_k127_7667335_1	760192.Halhy_4526	9.848e-135	437.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD3_k127_7667904_1	1166018.FAES_4166	1.2e-23	110.0	COG0526@1|root,COG0526@2|Bacteria,4PP7J@976|Bacteroidetes,47WQW@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_7667904_0	1279009.ADICEAN_00044	4.961e-97	326.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,47QHI@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD3_k127_7667904_2	1185876.BN8_01475	6.06e-05	52.0	COG0135@1|root,COG0135@2|Bacteria,4NMKY@976|Bacteroidetes,47PJ8@768503|Cytophagia	976|Bacteroidetes	E	isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HKD3_k127_7682566_7	709991.Odosp_3536	1.65e-10	64.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,22WV0@171551|Porphyromonadaceae	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
HKD3_k127_7682566_8	1132442.KB889752_gene3423	0.0001228	47.0	29S7Z@1|root,30DCG@2|Bacteria,1UB50@1239|Firmicutes,4IMHI@91061|Bacilli,1ZK63@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7682566_0	1122176.KB903565_gene3282	6.202e-279	882.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD3_k127_7682566_4	760192.Halhy_2807	9.094e-73	248.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1IRT0@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD3_k127_7682566_1	760192.Halhy_2808	9.129e-177	563.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1IQYP@117747|Sphingobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD3_k127_7682566_5	760192.Halhy_3448	1.617e-39	164.0	COG0500@1|root,COG0500@2|Bacteria,4NPKT@976|Bacteroidetes	976|Bacteroidetes	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
HKD3_k127_7682566_3	767434.Fraau_0334	2.785e-83	289.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1X3FM@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the RimK family	rimK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
HKD3_k127_7682566_2	1122176.KB903554_gene3852	1.714e-139	455.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD3_k127_7682566_6	1137281.D778_00963	1.611e-12	76.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_7685709_4	760192.Halhy_2149	3.583e-78	267.0	COG0652@1|root,COG3291@1|root,COG0652@2|Bacteria,COG3291@2|Bacteria,4NGT6@976|Bacteroidetes,1IQXS@117747|Sphingobacteriia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	PKD,Pro_isomerase
HKD3_k127_7685709_5	926554.KI912668_gene5093	4.749e-68	243.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD3_k127_7685709_3	1313421.JHBV01000051_gene177	4.466e-92	312.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1IRYG@117747|Sphingobacteriia	976|Bacteroidetes	M	transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
HKD3_k127_7685709_2	1123037.AUDE01000014_gene326	1.256e-157	516.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
HKD3_k127_7685709_1	385682.AFSL01000015_gene2712	2.228e-161	519.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,2FN59@200643|Bacteroidia,3XJVD@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD3_k127_7685709_6	760192.Halhy_1987	1.979e-47	184.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1IQBR@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HKD3_k127_7685709_0	1122176.KB903543_gene688	0.0	1069.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1INS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
HKD3_k127_7709214_2	1122176.KB903544_gene744	1.767e-65	231.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1IPUQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD3_k127_7709214_0	1122176.KB903565_gene3399	2.793e-186	590.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD3_k127_7709214_1	1122176.KB903565_gene3398	4.921e-111	362.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1IPWN@117747|Sphingobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD3_k127_7709214_3	1313421.JHBV01000049_gene111	2.911e-27	126.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1ISDW@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
HKD3_k127_7766598_0	926549.KI421517_gene421	1.962e-133	434.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_7766598_2	1073999.BN137_1089	5.865e-29	125.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,1S32G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	maa	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
HKD3_k127_7766598_3	771875.Ferpe_1102	4.244e-16	91.0	COG0554@1|root,COG0554@2|Bacteria,2GDTT@200918|Thermotogae	200918|Thermotogae	C	4-alpha-L-fucosyltransferase glycosyl transferase group 56	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_56
HKD3_k127_7766598_1	1120968.AUBX01000012_gene2724	7.635e-116	383.0	COG0399@1|root,COG0399@2|Bacteria,4NGI4@976|Bacteroidetes,47KCG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	vioA	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_789639_0	1303692.SFUL_1740	4.85e-09	68.0	COG0265@1|root,COG0265@2|Bacteria,2GJ15@201174|Actinobacteria	201174|Actinobacteria	O	PDZ DHR GLGF domain protein	sprJ	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_7923976_4	761193.Runsl_3529	8.627e-12	78.0	2EGR9@1|root,33AHE@2|Bacteria,4NXPH@976|Bacteroidetes,47VY8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7923976_2	1237149.C900_02163	4.95e-73	267.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7923976_1	468059.AUHA01000007_gene2663	1.619e-99	329.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IWQ3@117747|Sphingobacteriia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_7923976_0	1237149.C900_02165	6.965e-100	339.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_7923976_3	468059.AUHA01000007_gene2661	2.855e-69	243.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_7938368_9	760192.Halhy_4682	1.927e-135	445.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IQCY@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_7938368_14	886377.Murru_2812	2.702e-52	200.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
HKD3_k127_7938368_10	866536.Belba_0340	2.146e-119	391.0	COG0639@1|root,COG0639@2|Bacteria,4NIDG@976|Bacteroidetes,47MI8@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
HKD3_k127_7938368_8	526227.Mesil_2803	2.898e-136	442.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
HKD3_k127_7938368_18	1122179.KB890425_gene3382	2.656e-28	122.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,1IS6N@117747|Sphingobacteriia	976|Bacteroidetes	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
HKD3_k127_7938368_2	760192.Halhy_1699	4.143e-203	660.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPTT@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF1573,OmpA,PD40
HKD3_k127_7938368_16	1122176.KB903534_gene2217	1.081e-46	182.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,SLH,Toluene_X
HKD3_k127_7938368_12	1122176.KB903554_gene3849	6.598e-91	310.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1IXKD@117747|Sphingobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
HKD3_k127_7938368_7	1408813.AYMG01000029_gene4719	2.49e-142	465.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,1IR63@117747|Sphingobacteriia	976|Bacteroidetes	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD3_k127_7938368_5	1356852.N008_03065	2.655e-164	529.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
HKD3_k127_7938368_3	1121899.Q764_13255	5.599e-192	614.0	COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1HZMD@117743|Flavobacteriia,2NV6G@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HKD3_k127_7938368_1	313603.FB2170_16246	1.136e-214	685.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia,2PG35@252356|Maribacter	976|Bacteroidetes	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HKD3_k127_7938368_0	518766.Rmar_0074	1.966e-230	739.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1FIRV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
HKD3_k127_7938368_6	1122176.KB903565_gene3364	2.85e-149	477.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1IQZ5@117747|Sphingobacteriia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HKD3_k127_7938368_13	760192.Halhy_4856	2.477e-79	305.0	COG3210@1|root,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	976|Bacteroidetes	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	SprB
HKD3_k127_7938368_4	1484460.JSWG01000011_gene1805	5.037e-182	644.0	COG2304@1|root,COG3391@1|root,COG2304@2|Bacteria,COG3391@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia	976|Bacteroidetes	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
HKD3_k127_7938368_15	1122179.KB890447_gene186	1.944e-50	186.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1J0TI@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_7938368_11	1122176.KB903543_gene659	6.768e-98	325.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1IQDQ@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD3_k127_7996353_3	760192.Halhy_1701	3.092e-41	159.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HKD3_k127_7996353_0	1122176.KB903573_gene4825	8.325e-216	706.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IXNJ@117747|Sphingobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	npr	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
HKD3_k127_7996353_2	641526.ADIWIN_0002	1.153e-121	400.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1HX7P@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HKD3_k127_7996353_1	926562.Oweho_2011	3.289e-179	577.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1HWW2@117743|Flavobacteriia,2PAD6@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_8054064_0	1317122.ATO12_04495	0.0	1356.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2YIFW@290174|Aquimarina	976|Bacteroidetes	S	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_8054064_2	760192.Halhy_3100	1.643e-294	911.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IQQ4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
HKD3_k127_8054064_4	153721.MYP_194	8.072e-68	241.0	COG3386@1|root,COG3386@2|Bacteria,4NJKD@976|Bacteroidetes,47PXA@768503|Cytophagia	976|Bacteroidetes	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
HKD3_k127_8054064_3	385682.AFSL01000014_gene2746	2.145e-164	524.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia,3XIPP@558415|Marinilabiliaceae	976|Bacteroidetes	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_8054064_1	743722.Sph21_0674	0.0	1314.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD3_k127_8088503_1	153721.MYP_3261	8.108e-27	120.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	CHU_C,GSDH,Laminin_G_3,PKD
HKD3_k127_8088503_3	1492737.FEM08_20940	0.0004424	53.0	COG1345@1|root,COG1520@1|root,COG2356@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1520@2|Bacteria,COG2356@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
HKD3_k127_8088503_0	153721.MYP_3264	6.918e-165	578.0	COG1572@1|root,COG3210@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,47QVQ@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
HKD3_k127_8088503_2	1270193.JARP01000002_gene351	1.088e-10	77.0	COG1345@1|root,COG2911@1|root,COG3420@1|root,COG4886@1|root,COG1345@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria,COG4886@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Gal_Lectin,PA14
HKD3_k127_8103484_2	700598.Niako_6235	2.039e-107	359.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1IU84@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_8103484_1	925409.KI911562_gene2551	5.381e-134	433.0	COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,1IQHM@117747|Sphingobacteriia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
HKD3_k127_8103484_0	1122605.KB893625_gene2118	2.518e-190	610.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
HKD3_k127_8114373_14	1122176.KB903552_gene3706	3.941e-33	133.0	COG1522@1|root,COG1522@2|Bacteria,4NPYG@976|Bacteroidetes	976|Bacteroidetes	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
HKD3_k127_8114373_9	1122176.KB903552_gene3707	3.299e-65	228.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
HKD3_k127_8114373_15	926550.CLDAP_32710	2.052e-31	126.0	2ED2V@1|root,32VHB@2|Bacteria,2GBPF@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2568
HKD3_k127_8114373_0	984262.SGRA_1727	3.546e-195	618.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1IQ5C@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD3_k127_8114373_4	984262.SGRA_1930	5.018e-132	430.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1IQH3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_8114373_6	1157490.EL26_23050	1.041e-80	286.0	COG0726@1|root,COG0726@2|Bacteria,1VI89@1239|Firmicutes	1239|Firmicutes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8114373_16	1408473.JHXO01000006_gene1186	1.742e-25	115.0	28PRQ@1|root,2ZCDG@2|Bacteria,4NMCK@976|Bacteroidetes,2FYMQ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8114373_3	1122176.KB903587_gene4484	2.211e-172	558.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1IPRF@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_8114373_13	266748.HY04_10325	1.274e-38	160.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1I0XW@117743|Flavobacteriia,3ZP0H@59732|Chryseobacterium	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
HKD3_k127_8114373_1	626887.J057_20255	6.038e-182	586.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
HKD3_k127_8114373_12	616991.JPOO01000003_gene2337	1.622e-39	157.0	2A8A0@1|root,30XBB@2|Bacteria,4NNJN@976|Bacteroidetes,1I294@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
HKD3_k127_8114373_2	1121904.ARBP01000026_gene619	2.607e-175	582.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,47KSE@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD3_k127_8114373_8	33876.JNXY01000024_gene5118	2.76e-72	251.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria,4D8K4@85008|Micromonosporales	201174|Actinobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,RicinB_lectin_2,Ricin_B_lectin,ThuA
HKD3_k127_8114373_7	1122176.KB903534_gene2158	6.9e-74	256.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
HKD3_k127_8114373_5	760192.Halhy_3160	5.283e-94	317.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HKD3_k127_8114373_10	143224.JQMD01000002_gene3435	8.312e-60	212.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,1I1J9@117743|Flavobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD3_k127_8114373_11	1122176.KB903554_gene3906	1.513e-59	212.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1IP3T@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_8143713_1	925409.KI911562_gene2966	1.494e-175	557.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1INXG@117747|Sphingobacteriia	976|Bacteroidetes	EGP	major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
HKD3_k127_8143713_0	760192.Halhy_3384	9.002e-187	606.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1INT0@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
HKD3_k127_8143713_5	1121904.ARBP01000012_gene1325	5.853e-15	82.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD3_k127_8143713_4	760192.Halhy_3369	9.139e-69	247.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1IXQD@117747|Sphingobacteriia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_8143713_3	1120951.AUBG01000002_gene1429	6.286e-82	287.0	COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,1HYY0@117743|Flavobacteriia	976|Bacteroidetes	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
HKD3_k127_8143713_2	760192.Halhy_2589	2.035e-163	528.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1IQIK@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD3_k127_8186738_1	1313301.AUGC01000001_gene1690	5.464e-80	276.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes	976|Bacteroidetes	E	Aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD3_k127_8186738_0	1122179.KB890425_gene3336	2.852e-116	386.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HKD3_k127_8186738_2	1166018.FAES_3669	1.56e-35	143.0	2EBX7@1|root,335WI@2|Bacteria,4NV52@976|Bacteroidetes,47QDZ@768503|Cytophagia	976|Bacteroidetes	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
HKD3_k127_8288584_0	1283300.ATXB01000001_gene388	0.0	1267.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
HKD3_k127_8288584_2	1366050.N234_16785	1.936e-116	393.0	COG2124@1|root,COG2146@1|root,COG2124@2|Bacteria,COG2146@2|Bacteria,1MV75@1224|Proteobacteria,2VIRM@28216|Betaproteobacteria,1K55M@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,p450
HKD3_k127_8288584_1	760192.Halhy_2051	1.934e-175	598.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	4.6.1.1	ko:K01768,ko:K16923,ko:K19694	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00582,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.28	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_8339190_1	1107311.Q767_15090	1.285e-128	420.0	COG0560@1|root,COG0560@2|Bacteria,4NIF2@976|Bacteroidetes,1HZ6P@117743|Flavobacteriia,2NT55@237|Flavobacterium	976|Bacteroidetes	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
HKD3_k127_8339190_0	1453500.AT05_10945	4.106e-140	448.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_8344699_4	1392498.JQLH01000001_gene2122	4.251e-101	347.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1HY94@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_8344699_1	1122176.KB903565_gene3311	1.65e-184	596.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1INS7@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
HKD3_k127_8344699_2	760192.Halhy_3330	4.741e-118	383.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1IP15@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_8344699_3	1122176.KB903543_gene687	5.72e-117	395.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1IS7E@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_8344699_0	1122176.KB903540_gene121	0.0	1313.0	COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,1J0A5@117747|Sphingobacteriia	976|Bacteroidetes	CG	PA14	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,DUF1080,PA14
HKD3_k127_8344699_5	1122176.KB903551_gene4219	4.736e-48	185.0	COG3832@1|root,COG4978@1|root,COG3832@2|Bacteria,COG4978@2|Bacteria	2|Bacteria	J	glyoxalase III activity	glsA	-	3.5.1.2	ko:K01425,ko:K13652	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000,ko03000	-	-	-	GyrI-like,Polyketide_cyc2
HKD3_k127_8361689_0	1123248.KB893386_gene1888	3.179e-139	467.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1IVHN@117747|Sphingobacteriia	976|Bacteroidetes	P	COG1055 Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
HKD3_k127_8361689_1	391596.PBAL39_12613	4.384e-98	335.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,1IS79@117747|Sphingobacteriia	976|Bacteroidetes	P	Pfam Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD3_k127_8361689_4	929556.Solca_3574	1.41e-45	178.0	COG0392@1|root,COG0392@2|Bacteria,4NMZ1@976|Bacteroidetes,1IRX8@117747|Sphingobacteriia	976|Bacteroidetes	O	Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_8361689_2	760192.Halhy_3603	1.749e-80	292.0	COG1807@1|root,COG1807@2|Bacteria,4NIT6@976|Bacteroidetes,1IRPE@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_8361689_3	1123277.KB893175_gene1302	2.895e-73	270.0	COG1807@1|root,COG1807@2|Bacteria,4NIT6@976|Bacteroidetes,47K6Z@768503|Cytophagia	976|Bacteroidetes	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_8451062_6	517418.Ctha_1859	2.284e-14	77.0	COG0855@1|root,COG0855@2|Bacteria,1FEEH@1090|Chlorobi	2|Bacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD3_k127_8451062_5	760192.Halhy_1702	6.422e-17	93.0	COG5036@1|root,COG5036@2|Bacteria,4P8RG@976|Bacteroidetes	976|Bacteroidetes	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8451062_3	1121899.Q764_02925	8.047e-123	411.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1HWY6@117743|Flavobacteriia,2NSIQ@237|Flavobacterium	976|Bacteroidetes	S	flavoprotein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD3_k127_8451062_2	1123248.KB893318_gene4164	6.611e-155	502.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_8451062_0	760192.Halhy_0449	2.72e-193	611.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1IVDJ@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
HKD3_k127_8451062_1	867900.Celly_2276	3.122e-188	600.0	COG3263@1|root,COG3263@2|Bacteria,4NFNS@976|Bacteroidetes,1IJ9K@117743|Flavobacteriia,1F9XC@104264|Cellulophaga	976|Bacteroidetes	P	COGs COG3263 NhaP-type Na H and K H antiporter with a unique C-terminal domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
HKD3_k127_8451062_4	1443665.JACA01000052_gene1895	7.45e-66	230.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5M@976|Bacteroidetes,1I10P@117743|Flavobacteriia,2YIZN@290174|Aquimarina	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
HKD3_k127_8451062_7	1122176.KB903543_gene668	7.797e-11	67.0	COG0526@1|root,COG0526@2|Bacteria,4NK8N@976|Bacteroidetes	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_8474707_1	755732.Fluta_2044	5.426e-29	136.0	COG4386@1|root,COG4386@2|Bacteria,4PP0K@976|Bacteroidetes,1IKDR@117743|Flavobacteriia,2PBMA@246874|Cryomorphaceae	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD3_k127_8474707_0	1313421.JHBV01000028_gene1857	5.935e-83	306.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
HKD3_k127_8476887_4	1150600.ADIARSV_2084	1.726e-42	158.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_8476887_3	531844.FIC_00882	1.062e-75	262.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1HYH7@117743|Flavobacteriia,4069Q@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Amino acid kinase family	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_8476887_1	531844.FIC_00881	5.931e-140	450.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1HYDI@117743|Flavobacteriia,405WQ@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD3_k127_8476887_0	531844.FIC_00880	7.684e-161	523.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1HXQB@117743|Flavobacteriia,405TS@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_8476887_2	531844.FIC_00879	8.161e-122	399.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1HYTR@117743|Flavobacteriia,4061Q@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Semialdehyde dehydrogenase, NAD binding domain	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_8489426_3	1214242.B446_11745	8.338e-08	58.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_8489426_2	1267211.KI669560_gene2831	3.409e-13	76.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1IZAC@117747|Sphingobacteriia	976|Bacteroidetes	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
HKD3_k127_8489426_0	1122176.KB903532_gene2676	1.496e-196	660.0	COG3291@1|root,COG3291@2|Bacteria,4NUFV@976|Bacteroidetes	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HKD3_k127_8489426_1	616991.JPOO01000003_gene1993	2.193e-14	78.0	COG4772@1|root,COG4772@2|Bacteria,4PKTE@976|Bacteroidetes,1HYQZ@117743|Flavobacteriia,23FQP@178469|Arenibacter	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_8497402_11	1122179.KB890420_gene2490	2.29e-15	87.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
HKD3_k127_8497402_8	760192.Halhy_0345	4.765e-42	164.0	294GD@1|root,2ZRW7@2|Bacteria,4P6UK@976|Bacteroidetes	976|Bacteroidetes	S	SpoOM protein	-	-	-	-	-	-	-	-	-	-	-	-	Spo0M
HKD3_k127_8497402_9	984262.SGRA_1095	2.949e-38	148.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8497402_4	760192.Halhy_5427	1.53e-112	373.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1IP0Z@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
HKD3_k127_8497402_1	760192.Halhy_5426	1.9e-160	517.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
HKD3_k127_8497402_7	760192.Halhy_5425	1.463e-53	194.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_8497402_6	1122176.KB903609_gene5227	2.839e-67	239.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1ISRT@117747|Sphingobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HKD3_k127_8497402_0	1484460.JSWG01000006_gene3008	0.0	1287.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_8497402_2	1122176.KB903576_gene5011	1.551e-128	429.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1IP68@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HKD3_k127_8497402_3	485918.Cpin_3664	3.37e-125	408.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD3_k127_8497402_5	1122176.KB903535_gene1894	4.628e-81	299.0	COG2152@1|root,COG3291@1|root,COG2152@2|Bacteria,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_8508351_20	926556.Echvi_0304	3.299e-71	252.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,47JII@768503|Cytophagia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_8508351_7	760192.Halhy_3326	3.707e-183	581.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD3_k127_8508351_25	1408813.AYMG01000011_gene802	2.261e-24	108.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1ISSY@117747|Sphingobacteriia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HKD3_k127_8508351_5	1122176.KB903544_gene812	5.178e-197	620.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1IQJC@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HKD3_k127_8508351_1	1122176.KB903544_gene811	1.612e-319	1001.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1IQ0V@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
HKD3_k127_8508351_13	1123277.KB893209_gene5807	1.243e-91	311.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,47K0Q@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
HKD3_k127_8508351_19	929713.NIASO_11030	1.585e-72	253.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1IR1N@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HKD3_k127_8508351_21	1122176.KB903540_gene52	2.979e-62	223.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8508351_6	468059.AUHA01000006_gene2985	2.203e-184	587.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,1IRQU@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_8508351_16	760192.Halhy_6483	6.996e-84	293.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1IPVB@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_8508351_10	760192.Halhy_6483	1.721e-114	377.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1IPVB@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_8508351_18	1267211.KI669560_gene2543	5.532e-78	270.0	COG0586@1|root,COG0586@2|Bacteria,4NMPN@976|Bacteroidetes,1IWBE@117747|Sphingobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
HKD3_k127_8508351_9	1122176.KB903609_gene5205	3.945e-131	433.0	COG2819@1|root,COG2819@2|Bacteria,4PMBF@976|Bacteroidetes,1J188@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_8508351_2	1380600.AUYN01000009_gene1942	4.841e-274	880.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_8508351_15	421531.IX38_19825	1.119e-84	289.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1HY56@117743|Flavobacteriia,3ZR3E@59732|Chryseobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_8508351_24	1122621.ATZA01000039_gene2636	8.477e-51	187.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1ISTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
HKD3_k127_8508351_4	1392490.JHZX01000001_gene753	2.217e-208	674.0	COG3118@1|root,COG3118@2|Bacteria,4PND9@976|Bacteroidetes,1IKUJ@117743|Flavobacteriia	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_8508351_22	1453498.LG45_05095	4.698e-57	202.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1I1GF@117743|Flavobacteriia,2NVGE@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_8508351_0	1121889.AUDM01000004_gene2632	0.0	1166.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,2NSJJ@237|Flavobacterium	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_8508351_12	1267211.KI669560_gene1635	8.252e-95	321.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD3_k127_8508351_8	1341181.FLJC2902T_06110	7.906e-179	569.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia,2NTN7@237|Flavobacterium	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
HKD3_k127_8508351_14	929713.NIASO_09230	6.63e-86	293.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1IPBT@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
HKD3_k127_8508351_17	1121889.AUDM01000004_gene2636	4.337e-81	277.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1HXF5@117743|Flavobacteriia,2NUI3@237|Flavobacterium	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
HKD3_k127_8508351_23	1121899.Q764_07530	1.525e-51	199.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia,2P06C@237|Flavobacterium	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HKD3_k127_8508351_11	1121889.AUDM01000004_gene2659	4.809e-95	325.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia,2NUFJ@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8508351_3	1123277.KB893186_gene5460	3.994e-228	758.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47KTR@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_8508351_26	762903.Pedsa_0045	2.425e-17	94.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CHU_C,Calx-beta,CarboxypepD_reg,DUF11,Flg_new,HYR,PKD,SLH,SdrD_B,fn3
HKD3_k127_8510293_4	760192.Halhy_5694	9.347e-129	416.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1J0XQ@117747|Sphingobacteriia	976|Bacteroidetes	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8510293_5	926562.Oweho_2166	1.04e-78	269.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,2PABJ@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_8510293_0	760192.Halhy_2445	1.046e-317	987.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1IPW9@117747|Sphingobacteriia	976|Bacteroidetes	J	elongation factor G domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_8510293_10	1469613.JT55_00870	0.0001485	52.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,3FDE0@34008|Rhodovulum	28211|Alphaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
HKD3_k127_8510293_8	1122176.KB903534_gene2084	2.503e-19	92.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1IT9C@117747|Sphingobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD3_k127_8510293_9	760192.Halhy_4029	1.52e-17	82.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD3_k127_8510293_2	760192.Halhy_4014	1.864e-219	698.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD3_k127_8510293_3	1122176.KB903565_gene3315	6.969e-180	572.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD3_k127_8510293_6	760192.Halhy_4016	1.552e-76	262.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1IRD0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HKD3_k127_8510293_7	1122176.KB903565_gene3313	8.776e-61	215.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD3_k127_8510293_1	760192.Halhy_0603	7.527e-281	882.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1IUUE@117747|Sphingobacteriia	976|Bacteroidetes	EU	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
HKD3_k127_8516177_3	1121373.KB903665_gene3096	1.061e-107	355.0	COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,47T04@768503|Cytophagia	976|Bacteroidetes	S	COG NOG10142 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
HKD3_k127_8516177_9	296591.Bpro_0624	1.661e-23	108.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD3_k127_8516177_1	1122176.KB903531_gene2826	1.732e-192	610.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1IS31@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
HKD3_k127_8516177_10	755732.Fluta_0258	2.85e-13	81.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes,1IAKI@117743|Flavobacteriia,2PB7R@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8516177_5	984262.SGRA_2553	3.894e-89	308.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1IX1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_8516177_0	984262.SGRA_2795	0.0	1022.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD3_k127_8516177_6	760192.Halhy_4698	3.013e-87	299.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1IRSG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_8516177_8	1122176.KB903545_gene824	6.112e-29	120.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1ISX9@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD3_k127_8516177_7	760192.Halhy_4707	4.344e-39	153.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
HKD3_k127_8516177_4	313598.MED152_02255	2.089e-94	321.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1HWK9@117743|Flavobacteriia,3VVSH@52959|Polaribacter	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
HKD3_k127_8516177_2	760192.Halhy_4709	1.31e-138	447.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
HKD3_k127_8567099_14	760192.Halhy_0416	1.853e-28	118.0	COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,1IU16@117747|Sphingobacteriia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	thcC	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
HKD3_k127_8567099_6	1122176.KB903544_gene733	3.791e-105	349.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1IQ0E@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD3_k127_8567099_5	760192.Halhy_2453	3.046e-106	362.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1IR1T@117747|Sphingobacteriia	976|Bacteroidetes	CP	ABC-type Na efflux pump, permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD3_k127_8567099_17	1120953.AUBH01000003_gene1965	0.0001037	48.0	2E5J4@1|root,330AE@2|Bacteria,1QYT1@1224|Proteobacteria,1T3TB@1236|Gammaproteobacteria,46D5Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ykof
HKD3_k127_8567099_7	929713.NIASO_08790	4.494e-78	285.0	COG0526@1|root,COG0526@2|Bacteria,4NKFI@976|Bacteroidetes,1IRSC@117747|Sphingobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Redoxin
HKD3_k127_8567099_8	760192.Halhy_2349	7.843e-75	263.0	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
HKD3_k127_8567099_0	1122179.KB890417_gene3224	0.0	1095.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1IQSQ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HKD3_k127_8567099_12	880070.Cycma_2354	5.649e-44	165.0	COG0614@1|root,COG0614@2|Bacteria,4NRAK@976|Bacteroidetes,47XUD@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
HKD3_k127_8567099_1	761193.Runsl_1396	7.984e-175	559.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,47MVE@768503|Cytophagia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
HKD3_k127_8567099_11	765914.ThisiDRAFT_2526	3.945e-50	186.0	COG4276@1|root,COG4276@2|Bacteria,1N2Z3@1224|Proteobacteria,1SRI2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8567099_15	926560.KE387023_gene2058	6.264e-27	116.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
HKD3_k127_8567099_9	1122176.KB903534_gene2137	1.73e-56	200.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HKD3_k127_8567099_10	760192.Halhy_2729	5.253e-53	189.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1ISJG@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HKD3_k127_8567099_4	1122176.KB903534_gene2139	3.849e-107	352.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1IQSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HKD3_k127_8567099_2	760192.Halhy_2731	5.322e-115	376.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD3_k127_8567099_3	1122176.KB903534_gene2141	5.202e-112	365.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD3_k127_8567099_13	1122176.KB903564_gene3181	3.884e-35	139.0	COG3495@1|root,COG3495@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
HKD3_k127_8567099_16	1041826.FCOL_09550	7.852e-09	57.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2NSA1@237|Flavobacterium	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_8568125_1	1122176.KB903535_gene2006	2.193e-66	241.0	COG4733@1|root,COG5276@1|root,COG4733@2|Bacteria,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
HKD3_k127_8568125_2	760192.Halhy_1229	3.401e-42	157.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1IU9P@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART PUR-alpha beta gamma DNA RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
HKD3_k127_8568125_0	760192.Halhy_1228	2.372e-222	705.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1IPDM@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_8568125_4	1122225.AULQ01000005_gene2679	2.5e-18	94.0	COG3743@1|root,COG3743@2|Bacteria,4NQAU@976|Bacteroidetes,1I38D@117743|Flavobacteriia	976|Bacteroidetes	S	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8568125_3	1124780.ANNU01000021_gene2971	5.964e-29	130.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
HKD3_k127_8576089_1	1089550.ATTH01000001_gene2023	7.601e-75	258.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1FJQN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD3_k127_8576089_0	1122176.KB903536_gene1801	5.664e-84	309.0	COG0384@1|root,COG0384@2|Bacteria,4P4WG@976|Bacteroidetes	976|Bacteroidetes	S	phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8576089_2	1122179.KB890451_gene4543	3.646e-18	86.0	2DBTB@1|root,2ZAWY@2|Bacteria,4NIYP@976|Bacteroidetes,1J0WX@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
HKD3_k127_8586604_3	1123248.KB893386_gene1933	2.388e-46	175.0	COG2187@1|root,COG2187@2|Bacteria,4NKD3@976|Bacteroidetes,1IXH4@117747|Sphingobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
HKD3_k127_8586604_4	700598.Niako_2304	4.057e-35	140.0	COG0645@1|root,COG0645@2|Bacteria,4NSKU@976|Bacteroidetes,1J033@117747|Sphingobacteriia	976|Bacteroidetes	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
HKD3_k127_8586604_5	1166018.FAES_0145	2.35e-33	147.0	28KVV@1|root,2ZACB@2|Bacteria,4NHPI@976|Bacteroidetes,47MDK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8586604_9	1122176.KB903553_gene3669	0.0009304	52.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IPX2@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_8586604_2	926562.Oweho_0739	6.359e-117	384.0	COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,1HY8V@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
HKD3_k127_8586604_0	1117318.PRUB_20294	3.099e-199	654.0	COG1409@1|root,COG1409@2|Bacteria,1RE47@1224|Proteobacteria,1S434@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_8586604_6	584708.Apau_2309	2.418e-21	111.0	COG3210@1|root,COG3210@2|Bacteria,3TB3U@508458|Synergistetes	508458|Synergistetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_8586604_1	1123248.KB893359_gene2216	1.849e-190	623.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IRHX@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_8586604_7	1107311.Q767_02610	6.118e-10	65.0	2CBAK@1|root,302Q1@2|Bacteria,4PJRP@976|Bacteroidetes,1INII@117743|Flavobacteriia,2NZRS@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8586604_8	661478.OP10G_1409	0.0002511	49.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
HKD3_k127_8590050_0	247639.MGP2080_14966	2.947e-262	816.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
HKD3_k127_8590050_1	1120956.JHZK01000003_gene437	2.904e-107	355.0	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,2TVAB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	haloacid dehalogenase-like hydrolase	napD	-	-	-	-	-	-	-	-	-	-	-	HAD
HKD3_k127_862349_3	760192.Halhy_1720	2.229e-62	218.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,1J0WP@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_862349_0	1122176.KB903537_gene1677	2.601e-154	507.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1IUAV@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_862349_2	1227739.Hsw_2569	1.218e-64	247.0	COG1216@1|root,COG1216@2|Bacteria,4PKUG@976|Bacteroidetes,47YDT@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
HKD3_k127_862349_1	1122176.KB903541_gene250	1.144e-87	298.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1IQ08@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility associated	gldN	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_862349_4	1122176.KB903541_gene249	8.217e-09	56.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
HKD3_k127_8670127_2	1122176.KB903576_gene4964	8.871e-168	541.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1IR5B@117747|Sphingobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HKD3_k127_8670127_4	1122176.KB903576_gene4963	7.249e-164	527.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1IQJQ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
HKD3_k127_8670127_9	1122176.KB903576_gene4962	8.275e-39	154.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IRV2@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
HKD3_k127_8670127_8	760192.Halhy_1152	3.383e-119	398.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_8670127_7	760192.Halhy_1153	2.386e-126	415.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD3_k127_8670127_5	760192.Halhy_1154	1.411e-128	421.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD3_k127_8670127_6	388413.ALPR1_20043	3e-128	423.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,47KTX@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD3_k127_8670127_3	468059.AUHA01000004_gene2173	6.1e-165	530.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HKD3_k127_8670127_1	926549.KI421517_gene2667	1.101e-170	548.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_8670127_0	1122176.KB903576_gene4955	8.155e-174	568.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD3_k127_8670127_10	760192.Halhy_1159	7.626e-15	78.0	2ADW1@1|root,313N1@2|Bacteria,4P9FS@976|Bacteroidetes,1ITVW@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8670127_11	1211813.CAPH01000017_gene833	8.282e-09	57.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,22U6D@171550|Rikenellaceae	976|Bacteroidetes	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD3_k127_8671667_4	497965.Cyan7822_1073	1.717e-19	102.0	COG2931@1|root,COG2931@2|Bacteria,1GJ01@1117|Cyanobacteria,3KK5Z@43988|Cyanothece	1117|Cyanobacteria	Q	PFAM C-type lectin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_C
HKD3_k127_8671667_6	1492737.FEM08_18480	6.109e-10	71.0	COG1404@1|root,COG3210@1|root,COG4886@1|root,COG5295@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4886@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,1I57T@117743|Flavobacteriia,2NV1X@237|Flavobacterium	976|Bacteroidetes	UW	TIGRFAM Por_Secre_tail Por secretion system C-terminal sorting domain	-	-	4.2.2.20,4.2.2.21	ko:K08961	-	-	-	-	ko00000,ko01000	-	-	-	Lyase_8,Lyase_catalyt
HKD3_k127_8671667_2	56107.Cylst_3573	1.642e-23	112.0	COG2304@1|root,COG2304@2|Bacteria,1GQ8T@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Lectin C-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_C
HKD3_k127_8671667_7	1121887.AUDK01000004_gene431	2.835e-06	59.0	COG2911@1|root,COG3210@1|root,COG3533@1|root,COG4625@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,4PPKP@976|Bacteroidetes,1IKQ3@117743|Flavobacteriia,2P0T3@237|Flavobacterium	976|Bacteroidetes	U	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Laminin_G_3
HKD3_k127_8671667_5	1185876.BN8_01261	1.976e-19	95.0	COG2258@1|root,COG2258@2|Bacteria,4NQSE@976|Bacteroidetes,47Q91@768503|Cytophagia	976|Bacteroidetes	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
HKD3_k127_8671667_0	760192.Halhy_6038	4.526e-216	686.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_8671667_3	1122179.KB890458_gene808	6.037e-22	109.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	Peptidase_M56,TonB_C
HKD3_k127_8671667_1	518766.Rmar_2203	1.122e-103	344.0	COG1028@1|root,COG1028@2|Bacteria,4NIAZ@976|Bacteroidetes	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
HKD3_k127_8692408_1	700598.Niako_2567	1.092e-100	337.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HKD3_k127_8692408_0	1166018.FAES_3576	0.0	1271.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
HKD3_k127_8692408_2	929713.NIASO_00625	2.391e-12	71.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1INTW@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_8734371_2	760192.Halhy_4261	2.105e-98	325.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1IR2F@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
HKD3_k127_8734371_3	760192.Halhy_5547	6.207e-32	126.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1ITE1@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD3_k127_8734371_0	760192.Halhy_5546	2.593e-305	954.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1INMK@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD3_k127_8734371_1	1122176.KB903531_gene2975	9.637e-113	370.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_8739740_2	1122179.KB890446_gene388	1.136e-30	124.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IQQ6@117747|Sphingobacteriia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
HKD3_k127_8739740_3	926560.KE387027_gene355	1.79e-06	59.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1WJI4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Cell wall-associated hydrolase (invasion-associated protein)	-	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60
HKD3_k127_8739740_0	1122176.KB903531_gene2913	1.553e-218	685.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HKD3_k127_8739740_1	760192.Halhy_5568	1.195e-70	251.0	COG2067@1|root,COG2067@2|Bacteria,4PN73@976|Bacteroidetes,1IYCH@117747|Sphingobacteriia	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_8748788_3	1122176.KB903540_gene24	5.243e-46	172.0	COG0526@1|root,COG0526@2|Bacteria,4NQ06@976|Bacteroidetes,1ISI1@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD3_k127_8748788_2	760192.Halhy_3808	2.837e-54	196.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1ISPN@117747|Sphingobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HKD3_k127_8748788_0	700598.Niako_5504	1.032e-151	488.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD3_k127_8748788_4	1122179.KB890430_gene4298	4.801e-16	84.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1ITJJ@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
HKD3_k127_8748788_1	71421.HI_1170	9.08e-88	305.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1Y7MJ@135625|Pasteurellales	135625|Pasteurellales	EH	component i	pabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
HKD3_k127_8757581_0	1121875.KB907546_gene2698	1.377e-66	233.0	COG0664@1|root,COG0664@2|Bacteria,4NNT7@976|Bacteroidetes,1I1XI@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
HKD3_k127_8757581_3	216432.CA2559_01200	1.791e-07	62.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD3_k127_8757581_1	398720.MED217_16370	5.318e-44	170.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia,2XJBX@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Glycine cleavage H-protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
HKD3_k127_8757581_2	1123057.P872_20050	4.471e-43	171.0	COG1228@1|root,COG1228@2|Bacteria,4NHGA@976|Bacteroidetes,47N43@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD3_k127_8761984_2	385682.AFSL01000064_gene1732	6.811e-09	60.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,2FNH4@200643|Bacteroidia,3XINX@558415|Marinilabiliaceae	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_8761984_0	760192.Halhy_5161	1.393e-233	756.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1IQ77@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_8761984_1	760192.Halhy_5160	9.714e-67	242.0	COG4085@1|root,COG4085@2|Bacteria,4NIB0@976|Bacteroidetes,1ITET@117747|Sphingobacteriia	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,LTD
HKD3_k127_8781094_1	1121288.AULL01000011_gene1078	1.654e-212	668.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1I067@117743|Flavobacteriia,3ZNS9@59732|Chryseobacterium	976|Bacteroidetes	E	Beta-eliminating lyase	tpl	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
HKD3_k127_8781094_3	1267211.KI669560_gene2189	6.112e-39	149.0	COG2010@1|root,COG2010@2|Bacteria,4NQE3@976|Bacteroidetes,1IU8D@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrome_CBB3
HKD3_k127_8781094_2	1267211.KI669560_gene2190	1.822e-91	313.0	COG3278@1|root,COG3278@2|Bacteria,4NIGA@976|Bacteroidetes,1IP1A@117747|Sphingobacteriia	976|Bacteroidetes	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
HKD3_k127_8781094_4	1267211.KI669560_gene2190	4.817e-22	99.0	COG3278@1|root,COG3278@2|Bacteria,4NIGA@976|Bacteroidetes,1IP1A@117747|Sphingobacteriia	976|Bacteroidetes	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
HKD3_k127_8781094_0	867902.Ornrh_0091	0.0	1095.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HKD3_k127_8877976_1	760192.Halhy_4626	3.116e-105	344.0	COG1858@1|root,COG1858@2|Bacteria,4NGX7@976|Bacteroidetes	976|Bacteroidetes	P	Pfam Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
HKD3_k127_8877976_3	1121875.KB907549_gene2104	4.237e-32	132.0	COG3059@1|root,COG3059@2|Bacteria,4NNX8@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
HKD3_k127_8877976_2	1216967.L100_08894	5.715e-53	191.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1I2ZX@117743|Flavobacteriia,34Q87@308865|Elizabethkingia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD3_k127_8877976_0	929556.Solca_1389	6.679e-192	618.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_8904058_0	760192.Halhy_0097	2.644e-171	559.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_8904058_3	760192.Halhy_1085	1.813e-66	231.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1ISYC@117747|Sphingobacteriia	976|Bacteroidetes	K	acr, cog1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
HKD3_k127_8904058_1	679935.Alfi_2558	4.764e-101	336.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,22U7E@171550|Rikenellaceae	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HKD3_k127_8904058_2	555500.I215_04210	1.403e-87	291.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HX6R@117743|Flavobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD3_k127_8913656_5	1122179.KB890497_gene2878	1.779e-07	59.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD3_k127_8913656_2	485918.Cpin_0381	3.833e-51	185.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1IT1Y@117747|Sphingobacteriia	976|Bacteroidetes	O	TIGRFAM Peroxiredoxin, osmotically inducible protein C, subgroup	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
HKD3_k127_8913656_1	700598.Niako_2798	9.494e-61	234.0	COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,4NKED@976|Bacteroidetes,1ITWK@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_8913656_4	471854.Dfer_1502	7.363e-18	87.0	COG3279@1|root,COG3279@2|Bacteria,4NK6R@976|Bacteroidetes,47XDW@768503|Cytophagia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_8913656_6	1123248.KB893325_gene1176	3.902e-07	61.0	2DQVC@1|root,338X2@2|Bacteria,4NW3I@976|Bacteroidetes,1IU51@117747|Sphingobacteriia	976|Bacteroidetes	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
HKD3_k127_8913656_0	1230343.CANP01000037_gene2744	3.563e-112	381.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,1RRZ1@1236|Gammaproteobacteria,1JCFE@118969|Legionellales	118969|Legionellales	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
HKD3_k127_8913656_3	761193.Runsl_0033	2.663e-30	121.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,47JIU@768503|Cytophagia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
HKD3_k127_8986878_1	886377.Murru_1828	3.076e-191	608.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
HKD3_k127_8986878_3	1122179.KB890455_gene3022	5.29e-168	536.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
HKD3_k127_8986878_0	761193.Runsl_2931	2.766e-223	696.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,47JCV@768503|Cytophagia	976|Bacteroidetes	Q	Homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
HKD3_k127_8986878_4	1191523.MROS_1152	8e-156	499.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
HKD3_k127_8986878_2	760192.Halhy_0941	2.945e-169	542.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_8986878_5	1122197.ATWI01000010_gene915	1.691e-67	245.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,466DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2818 3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HKD3_k127_8986878_6	1123248.KB893328_gene932	7.272e-51	189.0	2CYFR@1|root,32T44@2|Bacteria,4P6IN@976|Bacteroidetes,1IZDY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
HKD3_k127_8989978_3	313606.M23134_07736	0.0001894	49.0	2ECA3@1|root,32QV4@2|Bacteria,4NRYD@976|Bacteroidetes,47QR1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8989978_1	485918.Cpin_3101	3.646e-43	173.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NPAJ@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_8989978_0	755732.Fluta_4061	4.55e-57	205.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1HXC7@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_8989978_2	349521.HCH_04710	1.228e-07	61.0	2C8HS@1|root,3332Q@2|Bacteria,1NGJM@1224|Proteobacteria,1SICC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9008621_0	1122176.KB903531_gene2944	8.33e-179	582.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_9008621_2	469381.Dpep_0096	1.904e-08	65.0	COG2197@1|root,COG2197@2|Bacteria,3TB23@508458|Synergistetes	508458|Synergistetes	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_9008621_1	1122176.KB903549_gene1226	8.834e-112	389.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_9008621_3	1313301.AUGC01000009_gene1090	1.041e-05	48.0	2E54J@1|root,32ZXH@2|Bacteria,4P2Q2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9100636_46	1313301.AUGC01000015_gene1866	1.262e-29	123.0	COG2378@1|root,COG2378@2|Bacteria,4NN6R@976|Bacteroidetes	976|Bacteroidetes	K	HTH domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
HKD3_k127_9100636_37	760192.Halhy_1262	4.88e-44	164.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,1J0WI@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HKD3_k127_9100636_26	760192.Halhy_4738	8.981e-65	222.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HKD3_k127_9100636_25	760192.Halhy_4739	1.002e-67	233.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1IRJ7@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HKD3_k127_9100636_0	760192.Halhy_4740	0.0	1212.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_9100636_30	760192.Halhy_4741	9.235e-57	199.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1ISQN@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HKD3_k127_9100636_19	1122176.KB903535_gene1953	1.649e-89	300.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HKD3_k127_9100636_23	1122176.KB903535_gene1952	1.666e-70	244.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,1IRTU@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HKD3_k127_9100636_44	1122176.KB903535_gene1951	5.728e-34	132.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,1ITE2@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
HKD3_k127_9100636_11	1122179.KB890458_gene654	1.006e-126	410.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1INT6@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
HKD3_k127_9100636_39	984262.SGRA_1841	7.957e-38	156.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1ISXF@117747|Sphingobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
HKD3_k127_9100636_38	1122176.KB903535_gene1948	7.665e-40	151.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1ISMN@117747|Sphingobacteriia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
HKD3_k127_9100636_13	760192.Halhy_4748	1.542e-118	387.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1IPKE@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HKD3_k127_9100636_29	1122176.KB903535_gene1946	1.057e-62	217.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1IRSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HKD3_k127_9100636_48	1122176.KB903535_gene1945	1.141e-21	99.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
HKD3_k127_9100636_45	760192.Halhy_4751	1.984e-32	127.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1IT9T@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
HKD3_k127_9100636_27	1122176.KB903535_gene1943	1.689e-64	222.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
HKD3_k127_9100636_43	648996.Theam_0268	3.387e-34	134.0	COG0198@1|root,COG0198@2|Bacteria,2G49J@200783|Aquificae	200783|Aquificae	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
HKD3_k127_9100636_20	760192.Halhy_4754	9.292e-86	286.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1IPX4@117747|Sphingobacteriia	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
HKD3_k127_9100636_40	1122176.KB903535_gene1940	3.09e-37	143.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,1IY7E@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
HKD3_k127_9100636_33	485918.Cpin_1629	1.14e-52	189.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1IS0B@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
HKD3_k127_9100636_22	760192.Halhy_4757	1.39e-75	257.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
HKD3_k127_9100636_41	402612.FP1323	1.375e-36	141.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia,2NW83@237|Flavobacterium	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
HKD3_k127_9100636_21	1122176.KB903535_gene1936	6.339e-77	267.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1IQ9B@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
HKD3_k127_9100636_50	1121481.AUAS01000008_gene3035	2.401e-16	80.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
HKD3_k127_9100636_36	1122176.KB903535_gene1934	8.13e-47	172.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1IRSX@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
HKD3_k127_9100636_3	1122176.KB903535_gene1933	6.715e-192	608.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1IPEC@117747|Sphingobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HKD3_k127_9100636_15	929556.Solca_3006	5.104e-106	350.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1IP59@117747|Sphingobacteriia	976|Bacteroidetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD3_k127_9100636_42	760192.Halhy_4764	7.736e-36	136.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1IT95@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HKD3_k127_9100636_51	1150600.ADIARSV_3606	6.419e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1IUD9@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HKD3_k127_9100636_32	1122621.ATZA01000014_gene3232	2.636e-54	192.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HKD3_k127_9100636_31	1122176.KB903535_gene1929	2.922e-55	196.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1ISSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HKD3_k127_9100636_18	1122176.KB903535_gene1928	1.581e-96	319.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD3_k127_9100636_5	760192.Halhy_4768	2.4e-171	543.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1IQ3D@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HKD3_k127_9100636_34	1122179.KB890431_gene4216	1.357e-51	188.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1IRYB@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HKD3_k127_9100636_6	760192.Halhy_4776	5.21e-150	484.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1IPSN@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HKD3_k127_9100636_2	1122179.KB890419_gene45	4.294e-202	636.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1IP9V@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HKD3_k127_9100636_52	1313301.AUGC01000010_gene941	1.654e-11	75.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HKD3_k127_9100636_8	1122176.KB903532_gene2576	3.915e-144	461.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
HKD3_k127_9100636_12	760192.Halhy_4515	3.624e-123	400.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_9100636_49	873517.HMPREF1977_2315	6.956e-21	108.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia,1EQ6H@1016|Capnocytophaga	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
HKD3_k127_9100636_35	760192.Halhy_1200	4.476e-48	178.0	COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,1ISBH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_9100636_17	1122176.KB903539_gene1387	8.489e-99	328.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQ3T@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_9100636_4	984262.SGRA_0764	8.565e-181	574.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD3_k127_9100636_10	1122179.KB890458_gene821	1.923e-131	430.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1INTB@117747|Sphingobacteriia	976|Bacteroidetes	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_9100636_7	1122176.KB903538_gene1506	4.167e-149	494.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1IV9F@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_9100636_24	760192.Halhy_4265	4.317e-70	244.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1INZ4@117747|Sphingobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HKD3_k127_9100636_9	755732.Fluta_2762	1.088e-141	461.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia,2PA4P@246874|Cryomorphaceae	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_9100636_14	984262.SGRA_2046	3.31e-110	391.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD3_k127_9100636_47	760192.Halhy_4801	2.788e-26	120.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_9100636_16	1122176.KB903576_gene4935	6.221e-99	342.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_9100636_1	1122176.KB903576_gene4936	3.941e-212	669.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1IQK8@117747|Sphingobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD3_k127_9100636_28	1122176.KB903576_gene4937	1.019e-63	231.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1INP3@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_9150532_8	1122179.KB890414_gene1783	4.277e-61	218.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HKD3_k127_9150532_10	439235.Dalk_1881	1.834e-11	77.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_9150532_2	760192.Halhy_1263	5.349e-216	686.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_9150532_6	1124780.ANNU01000005_gene2452	3.317e-74	261.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,47JRS@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_9150532_4	649349.Lbys_0975	3.456e-118	386.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_9150532_1	1131812.JQMS01000001_gene2965	5.354e-244	760.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia,2NTC8@237|Flavobacterium	976|Bacteroidetes	P	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_9150532_5	153721.MYP_4368	7.427e-95	313.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_9150532_7	1202532.FF52_08539	1.117e-71	250.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia,2NW8V@237|Flavobacterium	976|Bacteroidetes	S	Transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_9150532_3	760192.Halhy_2537	1.378e-135	440.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_9150532_0	760192.Halhy_2538	2.132e-271	844.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HKD3_k127_9150532_9	1239962.C943_03878	8.517e-21	95.0	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes,47RWR@768503|Cytophagia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
HKD3_k127_9171654_1	1120970.AUBZ01000029_gene1051	1.305e-29	123.0	COG2346@1|root,COG2346@2|Bacteria,1QBDE@1224|Proteobacteria,1S9FC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Group 1 truncated hemoglobin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD3_k127_9171654_2	1392498.JQLH01000001_gene1361	1.56e-20	106.0	COG3209@1|root,COG3210@1|root,COG5295@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,4PFJG@976|Bacteroidetes,1IGAI@117743|Flavobacteriia,2PHWN@252356|Maribacter	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
HKD3_k127_9171654_4	1297742.A176_01423	2.307e-06	60.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,PATR,Peptidase_S74
HKD3_k127_9171654_0	1123277.KB893174_gene5927	9.862e-49	196.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_9209945_1	929562.Emtol_2898	4.745e-61	216.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD3_k127_9209945_0	1122176.KB903543_gene520	1.503e-188	601.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_9261431_1	1122179.KB890447_gene179	7.671e-107	354.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1IP9S@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_9261431_2	1121957.ATVL01000008_gene4259	2.012e-48	179.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,47PQ9@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HKD3_k127_9261431_3	1122176.KB903556_gene4076	2.745e-41	159.0	29WC5@1|root,30HXS@2|Bacteria,4NNWN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9261431_0	1313421.JHBV01000027_gene1830	8.875e-118	391.0	COG1304@1|root,COG1304@2|Bacteria,4NJPE@976|Bacteroidetes,1IYN1@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
HKD3_k127_9261431_4	984262.SGRA_3436	6.356e-09	57.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
HKD3_k127_9270589_0	760192.Halhy_6011	3.338e-310	988.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1IPD0@117747|Sphingobacteriia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD3_k127_9270589_1	945713.IALB_1798	3.266e-95	318.0	COG1738@1|root,COG1738@2|Bacteria	2|Bacteria	S	queuosine salvage	CP_0807	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
HKD3_k127_9270589_2	309807.SRU_2721	1.435e-14	83.0	COG1680@1|root,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
HKD3_k127_9275340_0	755732.Fluta_2885	1.971e-40	173.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HKD3_k127_9275340_2	1313421.JHBV01000029_gene1882	1.397e-14	88.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,MAM,PKD,P_proprotein,fn3
HKD3_k127_9275340_3	1121904.ARBP01000002_gene7097	2.289e-05	54.0	2E691@1|root,330X3@2|Bacteria,4NVM3@976|Bacteroidetes,47RUJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_930468_2	1313421.JHBV01000022_gene4690	9.735e-117	381.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1IPAU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
HKD3_k127_930468_0	1122176.KB903542_gene325	1.785e-280	884.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
HKD3_k127_930468_1	1122176.KB903548_gene1190	3.836e-180	582.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1IPN2@117747|Sphingobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HKD3_k127_930468_3	1229276.DI53_1288	1.087e-42	167.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1IS1R@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
HKD3_k127_9312551_5	1265503.KB905176_gene4069	5.953e-12	66.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,2Q601@267889|Colwelliaceae	1236|Gammaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	mdeA	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_9312551_3	376686.Fjoh_4623	9.038e-65	235.0	COG3187@1|root,COG3650@1|root,COG3187@2|Bacteria,COG3650@2|Bacteria,4NN1R@976|Bacteroidetes,1I1BF@117743|Flavobacteriia,2NU13@237|Flavobacterium	976|Bacteroidetes	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META,NlpE
HKD3_k127_9312551_4	1341155.FSS13T_20390	1.516e-30	126.0	COG2261@1|root,COG2261@2|Bacteria,4NUXX@976|Bacteroidetes,1I5I1@117743|Flavobacteriia	976|Bacteroidetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
HKD3_k127_9312551_2	686340.Metal_0288	4.47e-82	279.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_9312551_0	1237149.C900_04113	1.354e-205	652.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
HKD3_k127_9312551_1	686340.Metal_0290	4.171e-94	316.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1XG19@135618|Methylococcales	135618|Methylococcales	H	Reversible hydration of carbon dioxide	-	-	-	-	-	-	-	-	-	-	-	-	Pro_CA
HKD3_k127_9377432_7	1341181.FLJC2902T_31040	9.463e-21	92.0	COG0702@1|root,COG0702@2|Bacteria,4NICI@976|Bacteroidetes,1IIU7@117743|Flavobacteriia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
HKD3_k127_9377432_2	909663.KI867150_gene216	2.336e-95	339.0	COG1807@1|root,COG1807@2|Bacteria,1R3XN@1224|Proteobacteria,42P5N@68525|delta/epsilon subdivisions,2WKH2@28221|Deltaproteobacteria,2MQ8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_9377432_6	313603.FB2170_14198	9.317e-26	117.0	2C3TU@1|root,2ZBKB@2|Bacteria,4NMMF@976|Bacteroidetes,1I1HI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9377432_1	1122176.KB903541_gene205	6.653e-228	732.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HKD3_k127_9377432_0	1121904.ARBP01000007_gene2960	1.449e-260	812.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,47M2W@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
HKD3_k127_9377432_3	1296416.JACB01000037_gene1429	7.063e-57	215.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1HXNW@117743|Flavobacteriia,2YI2T@290174|Aquimarina	976|Bacteroidetes	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HKD3_k127_9377432_5	1121430.JMLG01000001_gene2160	3.399e-33	140.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,261ZV@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HKD3_k127_9377432_4	760192.Halhy_4555	1.57e-33	136.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,1IT2K@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_939151_2	1123278.KB893433_gene687	1.05e-107	361.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,47K8K@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
HKD3_k127_939151_4	1237149.C900_00172	4.249e-94	334.0	COG1629@1|root,COG4771@2|Bacteria,4PM07@976|Bacteroidetes,47YPI@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_939151_7	760192.Halhy_3461	5.602e-73	254.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1IXS1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
HKD3_k127_939151_8	760192.Halhy_1163	9.037e-69	246.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_939151_3	1122176.KB903540_gene66	1.334e-98	346.0	2DZ33@1|root,34C9F@2|Bacteria,4P7CN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD3_k127_939151_6	760192.Halhy_4502	6.623e-89	301.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1IPN9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_939151_5	1313421.JHBV01000043_gene3214	6.064e-93	323.0	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes	976|Bacteroidetes	M	Bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
HKD3_k127_939151_11	1122176.KB903542_gene358	2.685e-24	118.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1ITMT@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HKD3_k127_939151_10	1122176.KB903540_gene105	8.594e-37	141.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ISRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HKD3_k127_939151_1	1122176.KB903540_gene106	1.493e-130	428.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1IP3D@117747|Sphingobacteriia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
HKD3_k127_939151_9	760192.Halhy_2419	5.098e-47	178.0	COG0421@1|root,COG0421@2|Bacteria,4NPK5@976|Bacteroidetes	976|Bacteroidetes	E	Spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
HKD3_k127_939151_0	313606.M23134_06773	6.415e-170	571.0	COG2911@1|root,COG3291@1|root,COG4447@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4NI13@976|Bacteroidetes,47NV6@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_9522326_2	1121930.AQXG01000002_gene2045	3.387e-44	169.0	COG4430@1|root,COG4430@2|Bacteria,4NKNI@976|Bacteroidetes,1ITNC@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
HKD3_k127_9522326_0	1122176.KB903544_gene754	1.113e-142	460.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1IQMY@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_9522326_1	984262.SGRA_3790	4.254e-121	394.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,1IVMW@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_9550089_1	1122179.KB890433_gene4061	7.232e-91	308.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes	976|Bacteroidetes	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,PKD
HKD3_k127_9550089_2	760192.Halhy_2065	1.758e-39	153.0	2A5JD@1|root,3301Q@2|Bacteria,4PQ2E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9550089_0	925409.KI911562_gene2430	0.0	1180.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
HKD3_k127_9550089_3	866771.HMPREF9296_0189	7.532e-29	120.0	COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes,2FTUH@200643|Bacteroidia	976|Bacteroidetes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
HKD3_k127_96544_1	1122176.KB903543_gene685	5.759e-122	403.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD3_k127_96544_4	1123278.KB893601_gene2732	2.326e-63	226.0	28KQR@1|root,2ZA8H@2|Bacteria,4NJJF@976|Bacteroidetes,47N2E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_96544_6	760192.Halhy_3642	3.313e-43	166.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HKD3_k127_96544_0	760192.Halhy_3056	1.896e-302	940.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_96544_8	1122176.KB903540_gene14	2.234e-34	136.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1ISSQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_96544_2	1122176.KB903546_gene1006	9.532e-100	335.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD3_k127_96544_7	760192.Halhy_2929	7.779e-35	152.0	2CJVV@1|root,32SAW@2|Bacteria,4NTMY@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_96544_3	1122176.KB903546_gene1008	2.449e-65	246.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1IPUT@117747|Sphingobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_96544_5	272123.Anacy_1909	6.515e-60	236.0	COG2931@1|root,COG3386@1|root,COG2931@2|Bacteria,COG3386@2|Bacteria,1G55H@1117|Cyanobacteria,1HTSK@1161|Nostocales	1117|Cyanobacteria	Q	Cadherin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin
HKD3_k127_98314_3	1122176.KB903542_gene363	6.589e-06	54.0	2AZ5E@1|root,31RC3@2|Bacteria,4NYUC@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_98314_0	1122176.KB903556_gene4072	7.866e-115	399.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
HKD3_k127_98314_1	760192.Halhy_2741	2.447e-68	243.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1IPUG@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_98314_2	760192.Halhy_2742	2.654e-38	149.0	COG2304@1|root,COG3291@1|root,COG4386@1|root,COG4935@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,COG4935@2|Bacteria,4P3B4@976|Bacteroidetes	976|Bacteroidetes	O	Immunoglobulin like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR
## 2372 queries scanned
## Total time (seconds): 122.35465240478516
## Rate: 19.39 q/s