## Sat Nov 16 10:28:56 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin9/HKD_3_bin.5.fa -m mmseqs --itype genome -o HKD_3_bin.5 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HKD_3_bin.5 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD3_k127_1021315_2	1166018.FAES_2380	7.383e-41	169.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,47Q9Y@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	xynT	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
HKD3_k127_1021315_1	1122605.KB893644_gene1499	4.003e-64	229.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,1IP2G@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
HKD3_k127_1021315_0	1195236.CTER_5362	6.03e-111	376.0	COG1331@1|root,COG1331@2|Bacteria,1VQ0S@1239|Firmicutes,24ZUZ@186801|Clostridia	186801|Clostridia	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1043032_6	1267211.KI669560_gene1040	7.913e-53	186.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1IT1Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD3_k127_1043032_9	1250278.JQNQ01000001_gene2357	1.324e-13	81.0	2AVE1@1|root,31M5W@2|Bacteria,4NS2G@976|Bacteroidetes,1I4MZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
HKD3_k127_1043032_7	761193.Runsl_2691	3.179e-36	147.0	2DICZ@1|root,32UAY@2|Bacteria,4NU7D@976|Bacteroidetes,47SYM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1043032_5	700598.Niako_5634	6.039e-79	270.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1IRI4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
HKD3_k127_1043032_2	1123248.KB893314_gene3632	2.54e-137	456.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
HKD3_k127_1043032_1	1267211.KI669560_gene1042	4.303e-151	484.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1IQW6@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
HKD3_k127_1043032_0	1267211.KI669560_gene1043	4.357e-250	795.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
HKD3_k127_1043032_4	1267211.KI669560_gene1047	2.458e-88	296.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1IQPW@117747|Sphingobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HKD3_k127_1043032_3	1123248.KB893330_gene389	6.636e-91	300.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1INU0@117747|Sphingobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD3_k127_1048448_5	1123248.KB893314_gene3615	9.492e-19	91.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU2I@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HKD3_k127_1048448_0	700598.Niako_6651	1.31e-101	335.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1IPXY@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD3_k127_1048448_4	700598.Niako_0126	4.535e-33	141.0	COG2067@1|root,COG2067@2|Bacteria,4PJ15@976|Bacteroidetes,1IXNX@117747|Sphingobacteriia	976|Bacteroidetes	I	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_1048448_3	1267211.KI669560_gene1340	3.014e-46	170.0	COG2905@1|root,COG2905@2|Bacteria,4NTKX@976|Bacteroidetes,1J0SE@117747|Sphingobacteriia	976|Bacteroidetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_1048448_2	1123248.KB893324_gene1749	3.312e-55	198.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1ITDM@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HKD3_k127_1048448_1	700598.Niako_6904	2.212e-60	212.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1ISAN@117747|Sphingobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HKD3_k127_1048448_6	1122605.KB893626_gene2561	1.348e-14	74.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1ITY0@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD3_k127_1124720_6	215803.DB30_5198	5.857e-12	75.0	2A7XS@1|root,30WXJ@2|Bacteria,1PBJA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1124720_4	700598.Niako_6026	9.947e-77	264.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1IW6H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
HKD3_k127_1124720_0	1267211.KI669560_gene1203	0.0	1258.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HKD3_k127_1124720_3	1313421.JHBV01000028_gene1857	2.036e-85	305.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
HKD3_k127_1124720_1	1450525.JATV01000006_gene1017	6.457e-130	421.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,1HYW6@117743|Flavobacteriia,2NUG8@237|Flavobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_1124720_2	1123277.KB893239_gene1208	3.63e-124	408.0	COG5285@1|root,COG5285@2|Bacteria,4NGMY@976|Bacteroidetes,47MFK@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
HKD3_k127_1124720_5	760192.Halhy_2410	2.131e-18	94.0	2E8IG@1|root,332WH@2|Bacteria,4NWJT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1172329_2	929562.Emtol_2744	1.8e-34	135.0	COG3507@1|root,COG3507@2|Bacteria,4NEMG@976|Bacteroidetes,47KCN@768503|Cytophagia	976|Bacteroidetes	G	PFAM coagulation factor 5 8 type	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43,fn3
HKD3_k127_1172329_1	1122605.KB893626_gene2437	6.343e-219	685.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IQRK@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
HKD3_k127_1172329_0	925409.KI911562_gene327	1.11e-225	713.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IPV2@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2329)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3131,Glycoamylase
HKD3_k127_1172329_3	391596.PBAL39_13320	8.291e-27	110.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1INPD@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD3_k127_1212706_14	1288963.ADIS_1925	1.613e-174	558.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD3_k127_1212706_46	1123248.KB893324_gene1729	6.466e-42	155.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
HKD3_k127_1212706_1	1123248.KB893323_gene1654	0.0	1178.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
HKD3_k127_1212706_38	1267211.KI669560_gene1427	6.985e-61	220.0	COG2267@1|root,COG2267@2|Bacteria,4PKB9@976|Bacteroidetes,1IZ4H@117747|Sphingobacteriia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD3_k127_1212706_33	700598.Niako_1512	4.513e-67	237.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1IRXA@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HKD3_k127_1212706_41	1123248.KB893337_gene2550	5.546e-54	191.0	COG0633@1|root,COG0633@2|Bacteria,4NTVJ@976|Bacteroidetes,1ITJK@117747|Sphingobacteriia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
HKD3_k127_1212706_47	1267211.KI669560_gene1429	1.719e-41	154.0	COG2975@1|root,COG2975@2|Bacteria,4NSUG@976|Bacteroidetes,1ITCB@117747|Sphingobacteriia	976|Bacteroidetes	S	FeS assembly protein IscX	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
HKD3_k127_1212706_36	700598.Niako_1624	1.422e-63	222.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1ISY0@117747|Sphingobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
HKD3_k127_1212706_23	925409.KI911562_gene2631	1.181e-95	324.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1IYC2@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD3_k127_1212706_35	1123248.KB893359_gene2143	6.832e-66	230.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1ISD6@117747|Sphingobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HKD3_k127_1212706_19	1123248.KB893359_gene2142	2.808e-134	440.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
HKD3_k127_1212706_45	925409.KI911562_gene2628	5.879e-42	157.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1ISTX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
HKD3_k127_1212706_28	925409.KI911562_gene2627	1.795e-82	282.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1212706_16	700598.Niako_2154	1.302e-168	534.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HKD3_k127_1212706_25	1267211.KI669560_gene1436	3.575e-90	311.0	COG4632@1|root,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes,1ITPU@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,fn3
HKD3_k127_1212706_55	1123248.KB893323_gene1617	2.066e-19	94.0	2DKFZ@1|root,309D6@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HKD3_k127_1212706_17	700598.Niako_2152	4.293e-150	481.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IWBC@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD3_k127_1212706_6	1267211.KI669560_gene1438	1.374e-262	816.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
HKD3_k127_1212706_12	929713.NIASO_08770	2.533e-206	651.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1IQCB@117747|Sphingobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HKD3_k127_1212706_11	700598.Niako_2149	3.06e-223	697.0	COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1IP6Q@117747|Sphingobacteriia	976|Bacteroidetes	G	glucose-1-phosphate adenylyltransferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD3_k127_1212706_13	1453500.AT05_10770	7.101e-199	631.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
HKD3_k127_1212706_8	925409.KI911562_gene2683	5.516e-248	780.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	amyA2	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
HKD3_k127_1212706_43	700598.Niako_2110	1.911e-49	186.0	28NAE@1|root,2ZBE7@2|Bacteria,4NJNX@976|Bacteroidetes,1IS37@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_1212706_10	1123248.KB893320_gene3844	1.394e-234	756.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1IQ3X@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD3_k127_1212706_7	1123248.KB893330_gene416	7.274e-254	798.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HKD3_k127_1212706_44	1267211.KI669560_gene1921	3.671e-46	172.0	COG2246@1|root,COG2246@2|Bacteria,4NSQN@976|Bacteroidetes,1ITAX@117747|Sphingobacteriia	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HKD3_k127_1212706_26	1122605.KB893643_gene604	1.712e-89	315.0	28M10@1|root,2ZAFW@2|Bacteria,4NIF8@976|Bacteroidetes,1ISGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
HKD3_k127_1212706_39	700598.Niako_7344	4.609e-57	217.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes	976|Bacteroidetes	S	Hydrolase with alpha beta fold protein	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD3_k127_1212706_21	1267211.KI669560_gene2690	4.326e-129	416.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1IVZZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD3_k127_1212706_54	1123248.KB893324_gene1745	9.963e-22	100.0	COG0607@1|root,COG0607@2|Bacteria,4P7K2@976|Bacteroidetes,1J038@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD3_k127_1212706_3	700598.Niako_7346	0.0	1018.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1IP14@117747|Sphingobacteriia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
HKD3_k127_1212706_27	1123248.KB893326_gene1492	1.517e-84	283.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1IQEI@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
HKD3_k127_1212706_52	1267211.KI669560_gene1519	2.491e-30	125.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_1212706_30	925409.KI911562_gene2583	2.737e-72	252.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1IRW3@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NlpC P60 family	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
HKD3_k127_1212706_40	925409.KI911562_gene2586	3.647e-56	206.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_1212706_18	1239962.C943_03655	4.675e-135	446.0	COG0469@1|root,COG0469@2|Bacteria,4NGQX@976|Bacteroidetes,47T9Y@768503|Cytophagia	976|Bacteroidetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
HKD3_k127_1212706_15	1123248.KB893337_gene2579	6.389e-170	535.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_1212706_20	1123248.KB893337_gene2578	3.652e-130	423.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD3_k127_1212706_5	700598.Niako_1152	1.567e-264	824.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1IPXI@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD3_k127_1212706_31	925409.KI911562_gene1819	2.105e-70	241.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1ITJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD3_k127_1212706_0	925409.KI911562_gene1818	0.0	1376.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1INQX@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
HKD3_k127_1212706_48	760192.Halhy_2361	9.195e-41	154.0	29EC5@1|root,301A4@2|Bacteria,4NP7Z@976|Bacteroidetes,1ISJ2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1212706_32	1267211.KI669560_gene2709	3.134e-69	244.0	COG0115@1|root,COG0115@2|Bacteria,4PFUA@976|Bacteroidetes,1IS3V@117747|Sphingobacteriia	976|Bacteroidetes	EH	Amino-transferase class IV	-	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_1212706_29	1279009.ADICEAN_01376	5.056e-73	253.0	COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,47NYV@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD3_k127_1212706_53	1122179.KB890413_gene4895	5.872e-24	106.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1ITUD@117747|Sphingobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD3_k127_1212706_4	1267211.KI669560_gene1020	1.769e-301	957.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IWT6@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_1212706_49	929703.KE386491_gene4202	1.892e-39	155.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47K73@768503|Cytophagia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
HKD3_k127_1212706_24	700598.Niako_4443	1.472e-94	316.0	COG2227@1|root,COG2227@2|Bacteria,4PKUR@976|Bacteroidetes,1J0TH@117747|Sphingobacteriia	976|Bacteroidetes	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
HKD3_k127_1212706_50	925409.KI911562_gene2256	4.436e-39	149.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IYEG@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD3_k127_1212706_42	700598.Niako_3687	5.098e-51	187.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1IU9P@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART PUR-alpha beta gamma DNA RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
HKD3_k127_1212706_9	1267211.KI669560_gene2276	1.446e-236	735.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HKD3_k127_1212706_2	929556.Solca_1053	0.0	1022.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,4NEK3@976|Bacteroidetes,1INMR@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
HKD3_k127_1212706_37	700598.Niako_0377	1.855e-61	215.0	COG0454@1|root,COG0456@2|Bacteria,4NNG9@976|Bacteroidetes,1ISS7@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD3_k127_1212706_34	929713.NIASO_02540	4.986e-66	231.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1IS5M@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
HKD3_k127_1212706_59	929703.KE386491_gene3419	3.286e-06	52.0	29ZAA@1|root,30M8N@2|Bacteria,4PA28@976|Bacteroidetes,47X2B@768503|Cytophagia	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HKD3_k127_1212706_56	742817.HMPREF9449_02751	4.303e-19	92.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,22YMZ@171551|Porphyromonadaceae	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HKD3_k127_1212706_51	1267211.KI669560_gene2279	2.056e-31	130.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1IT7G@117747|Sphingobacteriia	976|Bacteroidetes	M	peptidase M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_1212706_22	1123248.KB893315_gene3124	1.022e-119	406.0	COG0457@1|root,COG1729@1|root,COG3147@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3147@2|Bacteria,4NDV9@976|Bacteroidetes,1IQQP@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
HKD3_k127_1215257_8	1122605.KB893637_gene3059	4.639e-39	146.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1ISGE@117747|Sphingobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
HKD3_k127_1215257_0	700598.Niako_1610	6.769e-241	752.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_1215257_1	1279009.ADICEAN_02472	8.503e-187	589.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,47K95@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_1215257_4	1123248.KB893314_gene3570	9.476e-72	250.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1IRTC@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD3_k127_1215257_2	700598.Niako_0179	5.581e-160	508.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1INUM@117747|Sphingobacteriia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD3_k127_1215257_3	1123278.KB893603_gene1875	1.66e-99	364.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
HKD3_k127_1215257_6	760192.Halhy_2352	1.419e-52	190.0	COG0346@1|root,COG0346@2|Bacteria,4NQQA@976|Bacteroidetes,1IU93@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	gloA	-	4.4.1.5	ko:K01759,ko:K03827	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_3,Glyoxalase,Glyoxalase_4
HKD3_k127_1215257_7	1121373.KB903632_gene485	1.146e-41	157.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
HKD3_k127_1215257_5	1279009.ADICEAN_00635	2.767e-65	230.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M3Z@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_1236534_4	1123248.KB893316_gene4645	4.445e-84	297.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IVSZ@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0553 Superfamily II DNA RNA helicase SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
HKD3_k127_1236534_1	1265313.HRUBRA_02314	6.055e-146	482.0	COG0415@1|root,COG0415@2|Bacteria,1MX6J@1224|Proteobacteria,1RMEE@1236|Gammaproteobacteria,1J8BU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the DNA photolyase family	cry2	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
HKD3_k127_1236534_2	485918.Cpin_4695	1.98e-142	460.0	COG0598@1|root,COG0598@2|Bacteria,4NGM7@976|Bacteroidetes,1IWM4@117747|Sphingobacteriia	976|Bacteroidetes	P	Mg2 transporter protein, CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD3_k127_1236534_5	700598.Niako_4328	4.222e-62	222.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_1236534_3	391596.PBAL39_25405	1.533e-107	355.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1IPAM@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HKD3_k127_1236534_0	929562.Emtol_0696	2.666e-160	507.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,47J9D@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_1239473_6	929713.NIASO_09225	1.251e-13	71.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1IPGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
HKD3_k127_1239473_5	1267211.KI669560_gene1631	1.16e-43	162.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes,1J0FW@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD3_k127_1239473_2	1121889.AUDM01000004_gene2658	1.67e-68	237.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia,2NV62@237|Flavobacterium	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HKD3_k127_1239473_1	1121889.AUDM01000004_gene2659	1.81e-99	339.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia,2NUFJ@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1239473_3	700598.Niako_5288	5.935e-61	221.0	COG0664@1|root,COG0664@2|Bacteria,4NM5E@976|Bacteroidetes,1IS1K@117747|Sphingobacteriia	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_1239473_0	929713.NIASO_02965	1.907e-300	927.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD3_k127_1239473_4	1123248.KB893314_gene3656	1.249e-44	163.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1ITF1@117747|Sphingobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD3_k127_1239473_7	504472.Slin_4181	3.333e-07	59.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,47P2M@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PKD
HKD3_k127_1273549_2	908937.Prede_1048	0.0002582	46.0	COG4724@1|root,COG4724@2|Bacteria,4NHIA@976|Bacteroidetes,2FNF9@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 85	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_85,Laminin_G_3
HKD3_k127_1273549_0	1123248.KB893348_gene356	0.0	1665.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD3_k127_1273549_1	925409.KI911562_gene2103	1.202e-10	65.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1IQ45@117747|Sphingobacteriia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
HKD3_k127_1289402_10	1267211.KI669560_gene2302	1.039e-33	130.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_1289402_1	700598.Niako_0407	1.353e-257	818.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1IPTV@117747|Sphingobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD3_k127_1289402_0	1267211.KI669560_gene1396	4.887e-307	961.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IQWN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
HKD3_k127_1289402_4	865938.Weevi_0953	1.237e-98	337.0	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,1HXBG@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
HKD3_k127_1289402_5	700598.Niako_5341	4.142e-96	326.0	COG0726@1|root,COG0726@2|Bacteria,4NK5Y@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_1289402_7	1237149.C900_03593	3.232e-66	241.0	2DBB7@1|root,2Z85R@2|Bacteria,4NJNG@976|Bacteroidetes,47RTY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1289402_2	273121.WS0042	2.673e-138	461.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YND5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	asparagine	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_1289402_9	1121889.AUDM01000006_gene1472	7.505e-49	187.0	COG1247@1|root,COG1247@2|Bacteria,4NM05@976|Bacteroidetes,1I10N@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
HKD3_k127_1289402_3	700598.Niako_5343	3.485e-112	374.0	COG0438@1|root,COG0438@2|Bacteria,4NPUH@976|Bacteroidetes,1IXDT@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_1289402_13	1174528.JH992891_gene359	6.764e-06	51.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	cypM_2	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
HKD3_k127_1289402_6	985255.APHJ01000023_gene2596	1.694e-80	280.0	COG0438@1|root,COG0438@2|Bacteria,4NJR3@976|Bacteroidetes,1IGDV@117743|Flavobacteriia,2P5XU@244698|Gillisia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_1289402_8	1121889.AUDM01000006_gene1475	4.166e-66	239.0	COG0438@1|root,COG0438@2|Bacteria,4NP7T@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_1289402_11	926556.Echvi_2600	1.607e-33	140.0	COG0463@1|root,COG0463@2|Bacteria,4NS35@976|Bacteroidetes,47XIJ@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_1289402_12	269798.CHU_0858	5.82e-32	131.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,47KWP@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HKD3_k127_1290899_4	1094466.KQS_07115	6.38e-31	124.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2NWCA@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD3_k127_1290899_1	700598.Niako_2258	3.698e-159	510.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IRNA@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD3_k127_1290899_2	929556.Solca_4204	1.941e-120	402.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1IRJE@117747|Sphingobacteriia	976|Bacteroidetes	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
HKD3_k127_1290899_0	929556.Solca_4205	0.0	1287.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPE6@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD3_k127_1290899_3	929556.Solca_4206	2.148e-94	323.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,1INTJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HKD3_k127_1298399_1	760192.Halhy_4326	2.438e-63	237.0	COG0526@1|root,COG0526@2|Bacteria,4NKFI@976|Bacteroidetes,1IRSC@117747|Sphingobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Redoxin
HKD3_k127_1298399_0	760192.Halhy_0886	0.0	1480.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IWHI@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_1298399_2	700598.Niako_4607	2.648e-60	212.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1INW1@117747|Sphingobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD3_k127_1306575_0	485918.Cpin_4133	8.013e-243	763.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IWJE@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1306575_1	1454007.JAUG01000051_gene1785	8.537e-127	418.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1IPW8@117747|Sphingobacteriia	976|Bacteroidetes	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HKD3_k127_1306575_2	925409.KI911562_gene342	1.491e-99	331.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1IRF7@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_1306575_4	1239962.C943_00021	4.208e-10	64.0	COG1977@1|root,COG1977@2|Bacteria,4NXUN@976|Bacteroidetes,47SRD@768503|Cytophagia	976|Bacteroidetes	H	ThiS family	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD3_k127_1306575_3	929713.NIASO_16465	6.258e-59	210.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HKD3_k127_1314829_6	929556.Solca_3217	2.453e-06	53.0	28JKB@1|root,2Z9D6@2|Bacteria,4NJC1@976|Bacteroidetes,1IRBG@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1314829_0	925409.KI911562_gene417	0.0	1031.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
HKD3_k127_1314829_5	113395.AXAI01000008_gene829	2.785e-11	74.0	28HDQ@1|root,2Z7Q9@2|Bacteria,1R41M@1224|Proteobacteria,2TTYR@28211|Alphaproteobacteria,3JRNM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1314829_7	1232410.KI421418_gene2322	0.0004559	53.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,43U1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
HKD3_k127_1314829_4	1123248.KB893348_gene256	2.123e-51	201.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1IR1C@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
HKD3_k127_1314829_1	504472.Slin_6200	5.946e-128	423.0	COG1524@1|root,COG1524@2|Bacteria,4NFRQ@976|Bacteroidetes,47JI2@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD3_k127_1314829_3	925409.KI911562_gene418	5.355e-101	338.0	COG2602@1|root,COG2602@2|Bacteria,4NH11@976|Bacteroidetes,1IYF8@117747|Sphingobacteriia	976|Bacteroidetes	V	Penicillin binding protein transpeptidase domain	-	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
HKD3_k127_1314829_2	592029.DDD_0451	2.124e-120	394.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
HKD3_k127_134129_1	1267211.KI669560_gene2228	7.258e-158	509.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HKD3_k127_134129_6	925409.KI911562_gene1926	3.397e-79	271.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1ISRE@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_134129_8	946077.W5A_07612	3.814e-20	93.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD3_k127_134129_5	700598.Niako_2912	1.941e-85	291.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
HKD3_k127_134129_4	925409.KI911562_gene2720	2.029e-118	386.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,1INZY@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_134129_7	399739.Pmen_2192	6.812e-45	175.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
HKD3_k127_134129_0	929713.NIASO_18720	2.198e-262	818.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,1INMA@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
HKD3_k127_134129_3	1492737.FEM08_14600	8.017e-121	392.0	COG1028@1|root,COG1028@2|Bacteria,4NH6Y@976|Bacteroidetes,1HXA4@117743|Flavobacteriia,2NSD7@237|Flavobacterium	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD3_k127_134129_2	925409.KI911562_gene36	5.13e-139	445.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1IPCE@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD3_k127_1370255_8	1107311.Q767_00360	1.733e-93	341.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NIU0@976|Bacteroidetes,1HXV1@117743|Flavobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1370255_13	1356852.N008_09345	1.945e-21	111.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4114,Lactonase,Phage-tail_3
HKD3_k127_1370255_12	700598.Niako_3448	7.176e-37	148.0	COG1595@1|root,COG1595@2|Bacteria,4NRBP@976|Bacteroidetes	976|Bacteroidetes	K	RNA polymerase, sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_1370255_9	700598.Niako_3500	1.32e-63	233.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes	976|Bacteroidetes	PT	COG3712 Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_1370255_1	1454007.JAUG01000043_gene7	2.5e-323	1026.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NZSK@976|Bacteroidetes,1IW3X@117747|Sphingobacteriia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1370255_3	700598.Niako_3089	2.891e-228	743.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4P276@976|Bacteroidetes,1IWS8@117747|Sphingobacteriia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
HKD3_k127_1370255_7	1454007.JAUG01000043_gene6	7.291e-97	332.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_1370255_0	1454007.JAUG01000043_gene7	0.0	1099.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NZSK@976|Bacteroidetes,1IW3X@117747|Sphingobacteriia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1370255_4	700598.Niako_3086	5.237e-149	486.0	COG3193@1|root,COG3193@2|Bacteria,4PNUR@976|Bacteroidetes,1J0SV@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_1370255_11	700598.Niako_3085	2.044e-52	195.0	2DVZ7@1|root,33XT0@2|Bacteria,4P305@976|Bacteroidetes,1IXZF@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4843)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4843
HKD3_k127_1370255_5	700598.Niako_3084	7.841e-137	456.0	2DV0V@1|root,33TES@2|Bacteria,4P1AE@976|Bacteroidetes,1IWVT@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD-like family	-	-	-	-	-	-	-	-	-	-	-	-	PKD_2
HKD3_k127_1370255_2	925409.KI911562_gene1311	4.303e-232	743.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD3_k127_1370255_10	700598.Niako_3080	1.136e-53	214.0	COG0526@1|root,COG0526@2|Bacteria,4P0TY@976|Bacteroidetes,1IV45@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1370255_6	880070.Cycma_1221	4.025e-107	352.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	ChitinaseA_N,Lipase_GDSL_2
HKD3_k127_1370313_2	1267211.KI669560_gene1380	5.566e-99	325.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD3_k127_1370313_0	1122605.KB893627_gene2934	2.023e-163	523.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1IP0F@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD3_k127_1370313_1	714943.Mucpa_4311	6.811e-105	345.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1IQME@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_1370313_3	1150600.ADIARSV_3836	1.321e-92	315.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,1INSV@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
HKD3_k127_1370313_4	925409.KI911562_gene1783	6.999e-63	225.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,1ISAD@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
HKD3_k127_1370313_5	1423743.JCM14108_2982	1.93e-13	72.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,3F582@33958|Lactobacillaceae	91061|Bacilli	P	Natural resistance-associated macrophage protein	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_1384648_4	1121904.ARBP01000022_gene3484	5.84e-48	181.0	COG3568@1|root,COG3568@2|Bacteria,4NMQ9@976|Bacteroidetes,47M9K@768503|Cytophagia	976|Bacteroidetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_1384648_1	1408813.AYMG01000007_gene4293	5e-324	1037.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1J0JM@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	todS_10	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_1384648_0	1408813.AYMG01000007_gene4294	0.0	1089.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1IVQC@117747|Sphingobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_1384648_2	1408813.AYMG01000007_gene4295	2.439e-233	735.0	COG0614@1|root,COG0614@2|Bacteria,4NFDZ@976|Bacteroidetes	976|Bacteroidetes	P	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_1384648_3	1121904.ARBP01000005_gene4759	8.527e-178	577.0	COG4225@1|root,COG4225@2|Bacteria,4NG6C@976|Bacteroidetes,47J9H@768503|Cytophagia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
HKD3_k127_1384648_5	509635.N824_19455	6.647e-31	125.0	COG1331@1|root,COG1331@2|Bacteria,4PKHP@976|Bacteroidetes,1INQG@117747|Sphingobacteriia	976|Bacteroidetes	O	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
HKD3_k127_1420150_11	925409.KI911562_gene1184	1.064e-113	367.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1IQZ1@117747|Sphingobacteriia	976|Bacteroidetes	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HKD3_k127_1420150_12	1267211.KI669560_gene575	3.066e-71	248.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1IRC3@117747|Sphingobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HKD3_k127_1420150_9	1239962.C943_04547	5.729e-128	419.0	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,47NA8@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_1420150_16	1122621.ATZA01000002_gene1567	4.321e-27	120.0	COG5654@1|root,COG5654@2|Bacteria,4NTUP@976|Bacteroidetes,1IZ2I@117747|Sphingobacteriia	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
HKD3_k127_1420150_17	1122621.ATZA01000002_gene1568	1.788e-20	96.0	COG5642@1|root,COG5642@2|Bacteria,4NT6I@976|Bacteroidetes,1IZ43@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
HKD3_k127_1420150_10	1123248.KB893322_gene588	8.038e-122	398.0	COG1028@1|root,COG1028@2|Bacteria,4NIAZ@976|Bacteroidetes,1IUVU@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
HKD3_k127_1420150_6	694427.Palpr_0627	2.035e-184	608.0	COG0507@1|root,COG0514@1|root,COG0507@2|Bacteria,COG0514@2|Bacteria,4NF6J@976|Bacteroidetes,2FM19@200643|Bacteroidia,22X68@171551|Porphyromonadaceae	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	uvrD2	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
HKD3_k127_1420150_1	700598.Niako_6960	5.822e-244	761.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
HKD3_k127_1420150_8	1267211.KI669560_gene2766	2.183e-141	451.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
HKD3_k127_1420150_13	1122605.KB893626_gene2720	1.944e-64	227.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
HKD3_k127_1420150_15	485918.Cpin_4192	8.287e-29	119.0	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1IZ3T@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_1420150_4	1123248.KB893331_gene3799	6.433e-196	617.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD3_k127_1420150_14	1123248.KB893331_gene3798	1.607e-30	131.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ITMH@117747|Sphingobacteriia	976|Bacteroidetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD3_k127_1420150_0	1123248.KB893331_gene3797	5.435e-268	843.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPEH@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_1420150_3	700598.Niako_6951	6.363e-202	647.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
HKD3_k127_1420150_5	402612.FP2211	5.669e-187	600.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia,2NTCA@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
HKD3_k127_1420150_2	929562.Emtol_0826	5.675e-204	643.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
HKD3_k127_1420150_18	929562.Emtol_0825	1.783e-14	79.0	COG2863@1|root,COG2863@2|Bacteria	2|Bacteria	C	cytochrome	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_1420150_7	700598.Niako_4055	2.43e-151	486.0	COG2267@1|root,COG2267@2|Bacteria,4NFIJ@976|Bacteroidetes,1IQBD@117747|Sphingobacteriia	976|Bacteroidetes	I	Serine aminopeptidase, S33	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD3_k127_1423459_2	1123248.KB893324_gene1755	2.553e-69	237.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_1423459_0	925409.KI911562_gene292	4.319e-151	486.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1IQ3E@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_1423459_4	761193.Runsl_3244	1.137e-27	120.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,47R92@768503|Cytophagia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_1423459_1	1267211.KI669560_gene1084	1.309e-144	476.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,1IQYC@117747|Sphingobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
HKD3_k127_1423459_3	1267211.KI669560_gene1083	1.634e-39	151.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1IQG7@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
HKD3_k127_1436544_7	1123248.KB893348_gene359	1.067e-116	380.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD3_k127_1436544_4	1123248.KB893348_gene361	1.706e-254	851.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_1436544_16	1122179.KB890447_gene184	1.254e-11	80.0	COG1361@1|root,COG4447@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_1436544_3	1123248.KB893348_gene361	6.467e-295	968.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_1436544_15	1111730.ATTM01000001_gene1714	6.487e-14	87.0	COG1404@1|root,COG3391@1|root,COG3405@1|root,COG3420@1|root,COG4625@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,COG3405@2|Bacteria,COG3420@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,OmpA,SprB
HKD3_k127_1436544_6	1123248.KB893348_gene360	1.016e-142	463.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1IR38@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1436544_0	1123248.KB893348_gene361	0.0	1705.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD3_k127_1436544_14	1158294.JOMI01000003_gene2264	7.952e-17	94.0	2CV66@1|root,32SWY@2|Bacteria,4NT2K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1436544_17	1122605.KB893625_gene2316	3.373e-09	68.0	2FD8R@1|root,345AR@2|Bacteria,4P5VE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1436544_2	925409.KI911562_gene2832	5.34e-305	944.0	COG0443@1|root,COG0443@2|Bacteria,4NEHZ@976|Bacteroidetes,1IQ1C@117747|Sphingobacteriia	976|Bacteroidetes	O	heat shock protein 70	-	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
HKD3_k127_1436544_9	929713.NIASO_18390	6.376e-65	226.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1ISJ9@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
HKD3_k127_1436544_5	485918.Cpin_1916	7.117e-209	657.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IP9D@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
HKD3_k127_1436544_8	700598.Niako_1050	5.254e-86	317.0	COG1520@1|root,COG4935@1|root,COG1520@2|Bacteria,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes,1IYMI@117747|Sphingobacteriia	976|Bacteroidetes	O	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1436544_11	1237149.C900_01393	7.836e-57	213.0	COG0683@1|root,COG0683@2|Bacteria,4NKE7@976|Bacteroidetes	976|Bacteroidetes	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD3_k127_1436544_10	1089547.KB913013_gene3945	2.334e-58	208.0	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,47QBA@768503|Cytophagia	976|Bacteroidetes	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
HKD3_k127_1436544_12	485918.Cpin_6013	1.691e-36	144.0	2CSP1@1|root,32SRI@2|Bacteria,4NT1E@976|Bacteroidetes,1ITR8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1436544_1	700598.Niako_2097	0.0	1064.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD3_k127_1438416_3	1267211.KI669560_gene1016	1.135e-07	56.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
HKD3_k127_1438416_1	925409.KI911562_gene1946	4.143e-89	307.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1IRH3@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
HKD3_k127_1438416_0	700598.Niako_6632	3.215e-199	654.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_1438416_2	700598.Niako_6631	5.293e-78	268.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_1459593_2	1123277.KB893173_gene1724	2.877e-29	122.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47NKH@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_1459593_0	760192.Halhy_0212	9.93e-86	292.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,1IPNQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_1459593_1	504472.Slin_1815	2.729e-42	158.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,47JBV@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_1469350_0	700598.Niako_5667	2.095e-183	586.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_1469351_1	929556.Solca_2380	2.194e-208	656.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1IQ6C@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM coagulation factor 5 8 type	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
HKD3_k127_1469351_2	1267211.KI669560_gene248	8.735e-34	145.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes	976|Bacteroidetes	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_1469351_3	1163407.UU7_16080	8.636e-11	72.0	2EGGB@1|root,33A8B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1469351_0	1122605.KB893634_gene4197	1.823e-226	721.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_1472049_11	925409.KI911562_gene493	7.852e-09	57.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_1472049_6	925409.KI911562_gene494	5.464e-70	241.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD3_k127_1472049_9	172045.KS04_03930	1.503e-48	179.0	COG1670@1|root,COG1670@2|Bacteria,4NPQC@976|Bacteroidetes,1I27J@117743|Flavobacteriia,34S4Y@308865|Elizabethkingia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_1472049_10	929556.Solca_3548	2.082e-32	136.0	COG0457@1|root,COG0457@2|Bacteria,4PPB4@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1472049_1	929713.NIASO_17855	1.626e-206	645.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
HKD3_k127_1472049_7	1123248.KB893314_gene3368	6.541e-60	221.0	COG0438@1|root,COG0438@2|Bacteria,4NMR6@976|Bacteroidetes,1IV78@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_1472049_8	485918.Cpin_2372	2.596e-54	219.0	COG0438@1|root,COG0438@2|Bacteria,4NI3I@976|Bacteroidetes,1IRMM@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_1472049_0	700598.Niako_6781	3.172e-219	720.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,1IWJ0@117747|Sphingobacteriia	976|Bacteroidetes	H	COGs COG2192 carbamoyl transferase NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
HKD3_k127_1472049_5	700598.Niako_6782	9.626e-93	310.0	COG1216@1|root,COG1216@2|Bacteria,4NGHQ@976|Bacteroidetes,1IS78@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
HKD3_k127_1472049_2	925409.KI911562_gene565	6.665e-182	577.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1IRVU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HKD3_k127_1472049_3	1123248.KB893348_gene138	1.845e-162	518.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1IP7N@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD3_k127_1472049_4	700598.Niako_5811	1.496e-94	314.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
HKD3_k127_151915_0	485917.Phep_1255	2.562e-10	72.0	COG1331@1|root,COG1331@2|Bacteria,4NUA3@976|Bacteroidetes,1ITHU@117747|Sphingobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1522126_0	929562.Emtol_0926	1.257e-257	800.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,47K7D@768503|Cytophagia	976|Bacteroidetes	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_1522126_2	313594.PI23P_09125	9.179e-07	55.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,3VWMD@52959|Polaribacter	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_1522126_3	1034807.FBFL15_2978	1.486e-06	59.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin_8
HKD3_k127_1522126_1	1408813.AYMG01000014_gene1531	1.446e-48	181.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,1ITRD@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
HKD3_k127_1526668_5	700598.Niako_6470	1.201e-08	57.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1INKZ@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HKD3_k127_1526668_0	925409.KI911562_gene1016	0.0	1370.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1IPWZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
HKD3_k127_1526668_1	925409.KI911562_gene1015	5.979e-184	582.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1J0U0@117747|Sphingobacteriia	976|Bacteroidetes	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
HKD3_k127_1526668_4	1121898.Q766_03975	1.631e-49	190.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes,1IAW1@117743|Flavobacteriia,2NWKD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1526668_3	700598.Niako_6467	4.259e-74	260.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
HKD3_k127_1526668_2	700598.Niako_6465	2.115e-152	493.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1ISPB@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_15275_9	700598.Niako_0945	3.233e-47	177.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1IQHN@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD3_k127_15275_2	925409.KI911562_gene1904	5.887e-150	485.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,4NEVK@976|Bacteroidetes,1IP3J@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
HKD3_k127_15275_7	925409.KI911562_gene1863	7.836e-70	240.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1IS2Z@117747|Sphingobacteriia	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
HKD3_k127_15275_0	761193.Runsl_3068	0.0	1174.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_15275_3	929713.NIASO_08585	4.665e-125	407.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD3_k127_15275_10	485918.Cpin_1903	1.604e-46	171.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1ISBS@117747|Sphingobacteriia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD3_k127_15275_6	485918.Cpin_1904	1.303e-87	293.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1IRF3@117747|Sphingobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD3_k127_15275_1	1123248.KB893370_gene4965	1.783e-164	526.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1IP51@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_15275_5	929713.NIASO_01100	1.244e-100	332.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1INNH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HKD3_k127_15275_11	929713.NIASO_04015	7.994e-40	161.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,1IQH5@117747|Sphingobacteriia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
HKD3_k127_15275_4	485918.Cpin_1917	6.654e-117	383.0	COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,1IPJU@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HKD3_k127_15275_12	754436.JCM19237_4164	8.587e-12	68.0	COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria,1S8C4@1236|Gammaproteobacteria,1XV1Q@135623|Vibrionales	135623|Vibrionales	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
HKD3_k127_153105_3	925409.KI911562_gene115	6.987e-91	304.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,1IWHH@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD3_k127_153105_2	1123248.KB893329_gene4479	5.241e-140	458.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,1J0U6@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_153105_4	1123248.KB893329_gene4478	5.235e-63	227.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1ISYC@117747|Sphingobacteriia	976|Bacteroidetes	K	acr, cog1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
HKD3_k127_153105_9	1123248.KB893385_gene4773	3.232e-31	125.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1ITVV@117747|Sphingobacteriia	976|Bacteroidetes	C	ATP synthase	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
HKD3_k127_153105_1	1267211.KI669560_gene1169	6.56e-296	911.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD3_k127_153105_10	1203611.KB894549_gene2286	1.256e-30	124.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,2FTD1@200643|Bacteroidia,22VHJ@171550|Rikenellaceae	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD3_k127_153105_0	1123248.KB893314_gene3387	2.6e-322	1045.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPAB@117747|Sphingobacteriia	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
HKD3_k127_153105_8	700598.Niako_4930	9.329e-36	143.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,1IU3T@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane chaperone Skp	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_153105_5	925409.KI911562_gene2126	8.83e-58	205.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1ISE3@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HKD3_k127_153105_11	925409.KI911562_gene2171	1.963e-26	112.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1ITWJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HKD3_k127_153105_7	1267211.KI669560_gene1564	1.044e-40	157.0	2FEUI@1|root,346TG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_153105_6	1122605.KB893625_gene2040	1.616e-42	156.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_154216_0	1267211.KI669560_gene742	8.15e-180	565.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,1IVIY@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HKD3_k127_154216_1	1107311.Q767_01830	4.308e-88	308.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1HY94@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_154216_2	1185876.BN8_02703	1.787e-58	216.0	COG2207@1|root,COG2207@2|Bacteria,4NJUT@976|Bacteroidetes,47P27@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_1567217_1	1121957.ATVL01000007_gene1650	2.831e-108	355.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_1567217_2	1128421.JAGA01000004_gene2533	2.697e-32	136.0	COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,DUF389
HKD3_k127_1567217_0	929556.Solca_2104	1.923e-159	510.0	28JHC@1|root,2Z9AX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
HKD3_k127_1584151_1	925409.KI911562_gene547	7.804e-124	402.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
HKD3_k127_1584151_0	700598.Niako_2651	3.783e-182	574.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
HKD3_k127_1584151_2	925409.KI911562_gene2927	2.914e-90	310.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1INQI@117747|Sphingobacteriia	976|Bacteroidetes	G	3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
HKD3_k127_1585611_6	700598.Niako_1111	2.408e-98	352.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,1IT0V@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD3_k127_1585611_8	1123248.KB893315_gene3091	6.863e-52	190.0	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,1IS9H@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_1585611_5	1123248.KB893315_gene3092	2.428e-103	350.0	COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,1IR65@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_1585611_4	1123248.KB893315_gene3093	2.003e-108	359.0	COG0845@1|root,COG0845@2|Bacteria,4NGVX@976|Bacteroidetes,1IQ7U@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG1566 Multidrug resistance efflux pump	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD3_k127_1585611_2	742767.HMPREF9456_01125	3.816e-117	387.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,2FWZE@200643|Bacteroidia,22W0S@171551|Porphyromonadaceae	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_1585611_3	1123248.KB893315_gene3095	6.459e-110	360.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1IWS4@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_1585611_1	700598.Niako_4469	5.289e-147	473.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes	976|Bacteroidetes	V	transport, permease protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD3_k127_1585611_0	700598.Niako_4468	1.667e-152	491.0	COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD3_k127_1585611_7	926549.KI421517_gene3538	1.945e-86	289.0	COG1985@1|root,COG1985@2|Bacteria,4PAUI@976|Bacteroidetes,47V1G@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD3_k127_1587750_6	929713.NIASO_04810	7.796e-69	237.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_1587750_2	1123248.KB893332_gene2272	6.439e-110	359.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD3_k127_1587750_1	1123248.KB893314_gene3476	7.582e-139	453.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
HKD3_k127_1587750_4	700598.Niako_2637	8.578e-92	315.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,1IWXG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_1587750_7	700598.Niako_2636	2.141e-41	153.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1ISVD@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD3_k127_1587750_0	485918.Cpin_6517	0.0	1082.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1INMK@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD3_k127_1587750_5	929713.NIASO_09685	2.588e-73	257.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1IQ5D@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HKD3_k127_1587750_3	925409.KI911562_gene2046	7.307e-96	317.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HKD3_k127_1587750_8	1267211.KI669560_gene1973	7.611e-06	51.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1J0JU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD3_k127_1587750_9	1120951.AUBG01000017_gene3288	0.0007647	44.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1HZ8D@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD3_k127_1609181_9	583355.Caka_0059	1.744e-12	71.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.83	ko:K20846	-	-	-	-	ko00000,ko01000	-	GH16	-	Big_4,Glyco_hydro_16,RicinB_lectin_2
HKD3_k127_1609181_8	1123248.KB893330_gene410	2.422e-71	244.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD3_k127_1609181_0	1123248.KB893330_gene411	0.0	1050.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IPWF@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD3_k127_1609181_5	485917.Phep_1703	5.478e-134	439.0	COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,1IRAJ@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
HKD3_k127_1609181_6	945713.IALB_0194	1.297e-94	321.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,YdjC
HKD3_k127_1609181_2	153948.NAL212_2273	2.873e-179	573.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2VH7S@28216|Betaproteobacteria,3724K@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
HKD3_k127_1609181_3	1123248.KB893370_gene5092	5.773e-154	493.0	COG1236@1|root,COG1236@2|Bacteria,4NFN7@976|Bacteroidetes,1IPN3@117747|Sphingobacteriia	976|Bacteroidetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
HKD3_k127_1609181_1	485918.Cpin_6857	4.893e-218	689.0	COG1793@1|root,COG1793@2|Bacteria,4NEKP@976|Bacteroidetes,1IQCK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
HKD3_k127_1609181_4	700598.Niako_5069	7.399e-152	492.0	COG1858@1|root,COG1858@2|Bacteria,4NM2S@976|Bacteroidetes,1IVVD@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_1609181_7	1267211.KI669560_gene2394	8.019e-78	275.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1INS9@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
HKD3_k127_1614049_0	388413.ALPR1_09490	4.94e-220	692.0	COG0654@1|root,COG0654@2|Bacteria,4PMC5@976|Bacteroidetes,47UAM@768503|Cytophagia	976|Bacteroidetes	CH	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HKD3_k127_1614049_1	742725.HMPREF9450_00765	1.38e-107	361.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,2FTNK@200643|Bacteroidia	976|Bacteroidetes	G	Trehalase	treA	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase,Trehalase_Ca-bi
HKD3_k127_1614899_8	1313304.CALK_0463	1.061e-42	181.0	COG1404@1|root,COG5492@1|root,COG1404@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.52,3.4.21.66	ko:K08651,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH20	-	Autotransporter,Big_2,Peptidase_S8,Peptidase_S8_N
HKD3_k127_1614899_10	1356852.N008_08500	3.109e-15	91.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
HKD3_k127_1614899_9	1121481.AUAS01000015_gene2212	3.516e-32	146.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43,fn3
HKD3_k127_1614899_2	485918.Cpin_4713	1.155e-190	601.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD3_k127_1614899_7	1267211.KI669560_gene1423	4.388e-43	162.0	COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,1IYKP@117747|Sphingobacteriia	976|Bacteroidetes	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
HKD3_k127_1614899_6	511062.GU3_04015	3.023e-43	163.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1Y4KW@135624|Aeromonadales	135624|Aeromonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HKD3_k127_1614899_5	700598.Niako_1602	2.556e-50	184.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1ITF8@117747|Sphingobacteriia	976|Bacteroidetes	F	cytidine and deoxycytidylate deaminase	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD3_k127_1614899_0	1123248.KB893316_gene4625	3.56e-212	671.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD3_k127_1614899_4	1123248.KB893316_gene4624	1.258e-64	232.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1IS5U@117747|Sphingobacteriia	976|Bacteroidetes	K	MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
HKD3_k127_1614899_1	700598.Niako_1599	2.916e-193	608.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD3_k127_1614899_3	925409.KI911562_gene2892	5.621e-121	390.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1IP0Z@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
HKD3_k127_1623237_1	929556.Solca_3213	3.365e-141	466.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IR4R@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 39	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
HKD3_k127_1623237_3	945713.IALB_2311	3.971e-14	86.0	COG1409@1|root,COG2382@1|root,COG2885@1|root,COG1409@2|Bacteria,COG2382@2|Bacteria,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	3.1.4.53,5.2.1.8	ko:K03651,ko:K03771,ko:K07017	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000,ko03110	-	-	-	DUF3575,Esterase,Metallophos,OmpA,PD40,Rotamase,Rotamase_3
HKD3_k127_1623237_0	700598.Niako_0113	0.0	1195.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1IR3G@117747|Sphingobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
HKD3_k127_1623237_2	1122605.KB893625_gene1750	4.046e-16	78.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD3_k127_163971_3	1185876.BN8_05064	6.954e-52	192.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_163971_2	1123248.KB893370_gene5038	1.379e-86	292.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1IV4X@117747|Sphingobacteriia	976|Bacteroidetes	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_163971_1	1434325.AZQN01000001_gene665	1.49e-109	361.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_163971_0	468059.AUHA01000005_gene2446	5.901e-245	764.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IUW3@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_163971_4	550540.Fbal_2648	4.792e-14	78.0	COG0607@1|root,COG0607@2|Bacteria,1RHVM@1224|Proteobacteria,1SD9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0607 Rhodanese-related sulfurtransferase	pspE	GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K03972	-	-	-	-	ko00000	-	-	iE2348C_1286.E2348C_1500,iECABU_c1320.ECABU_c15910,iSDY_1059.SDY_1936,ic_1306.c1779	Rhodanese
HKD3_k127_1640878_4	925409.KI911562_gene2120	7.218e-143	460.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1INMG@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
HKD3_k127_1640878_6	1123248.KB893314_gene3692	2.199e-100	351.0	COG4389@1|root,COG4389@2|Bacteria,4NH21@976|Bacteroidetes,1IQTF@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM site-specific recombinase	-	-	-	-	-	-	-	-	-	-	-	-	SpecificRecomb
HKD3_k127_1640878_7	700598.Niako_6681	5.938e-82	278.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,1IXAV@117747|Sphingobacteriia	976|Bacteroidetes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HKD3_k127_1640878_0	1267211.KI669560_gene794	1.223e-218	687.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,1IV8P@117747|Sphingobacteriia	976|Bacteroidetes	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
HKD3_k127_1640878_5	925409.KI911562_gene2912	3.839e-136	437.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1IQIJ@117747|Sphingobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
HKD3_k127_1640878_3	925409.KI911562_gene2911	2.851e-168	538.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1IQWR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HKD3_k127_1640878_2	1123248.KB893326_gene1321	1.413e-177	569.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1IQ0J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_1640878_1	1123248.KB893326_gene1324	1.144e-194	612.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1IP4B@117747|Sphingobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
HKD3_k127_1640878_8	1313301.AUGC01000014_gene2454	1.648e-73	254.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD3_k127_1676584_4	525257.HMPREF0204_10212	5.551e-26	120.0	COG5571@1|root,COG5571@2|Bacteria,4NMTM@976|Bacteroidetes,1I1Q2@117743|Flavobacteriia,3ZPWR@59732|Chryseobacterium	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
HKD3_k127_1676584_0	700598.Niako_6918	8.262e-215	677.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,1IPWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
HKD3_k127_1676584_2	485918.Cpin_0811	1.119e-109	374.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1IS6V@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
HKD3_k127_1676584_3	925409.KI911562_gene1245	1.163e-62	227.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1IXYF@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD3_k127_1676584_1	700598.Niako_6920	7.684e-132	428.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1IQ15@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
HKD3_k127_1688342_7	925409.KI911562_gene2981	8.595e-40	152.0	28KFX@1|root,2ZA1W@2|Bacteria,4P3W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1688342_6	1267211.KI669560_gene1847	1.706e-43	167.0	COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,1ISU6@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD3_k127_1688342_8	925409.KI911562_gene2307	4.677e-32	139.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1IT0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1688342_0	925409.KI911562_gene2306	5.028e-275	852.0	COG1884@1|root,COG1884@2|Bacteria,4PN0H@976|Bacteroidetes,1IPCT@117747|Sphingobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HKD3_k127_1688342_2	468059.AUHA01000005_gene2521	1.352e-185	595.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	ampH	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Beta-lactamase2,DUF3471
HKD3_k127_1688342_1	485918.Cpin_3266	8.068e-190	601.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_1688342_4	925409.KI911562_gene2966	2.798e-180	572.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1INXG@117747|Sphingobacteriia	976|Bacteroidetes	EGP	major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
HKD3_k127_1688342_5	485918.Cpin_1183	1.142e-69	250.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,1J0KY@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1688342_3	1239962.C943_03918	2.846e-183	626.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Peptidase_S8_N
HKD3_k127_169456_4	700598.Niako_4561	1.785e-27	112.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HKD3_k127_169456_5	929713.NIASO_18380	1.407e-22	104.0	COG5642@1|root,COG5642@2|Bacteria,4NX1V@976|Bacteroidetes,1IUEV@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
HKD3_k127_169456_3	1121481.AUAS01000002_gene3245	4.85e-28	118.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,47SA7@768503|Cytophagia	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
HKD3_k127_169456_1	1267211.KI669560_gene1992	3.556e-116	380.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1IQ9S@117747|Sphingobacteriia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD3_k127_169456_2	1122605.KB893637_gene3406	4.882e-96	318.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1ISGF@117747|Sphingobacteriia	976|Bacteroidetes	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
HKD3_k127_169456_0	1123248.KB893318_gene4191	1.292e-215	697.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1IPU7@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HKD3_k127_1715629_53	929713.NIASO_06930	1.496e-75	254.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1IPCR@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD3_k127_1715629_52	1484460.JSWG01000001_gene2355	7.835e-76	264.0	COG4122@1|root,COG4122@2|Bacteria,4NJV1@976|Bacteroidetes,1HYRV@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD3_k127_1715629_44	700598.Niako_1141	2.965e-96	320.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HKD3_k127_1715629_72	925409.KI911562_gene2949	1.214e-36	148.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1ITDS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1715629_33	925409.KI911562_gene2948	1.553e-132	429.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1IPCV@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD3_k127_1715629_30	925409.KI911562_gene2947	5.987e-142	454.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1IQ5V@117747|Sphingobacteriia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD3_k127_1715629_45	485918.Cpin_2032	6.743e-94	314.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
HKD3_k127_1715629_27	929713.NIASO_12095	2.479e-158	510.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1IPSC@117747|Sphingobacteriia	976|Bacteroidetes	S	DNA mismatch repair protein MutT	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HKD3_k127_1715629_73	1267211.KI669560_gene2164	1.394e-35	143.0	COG3637@1|root,COG3637@2|Bacteria,4NWNN@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_1715629_9	1121481.AUAS01000003_gene3797	7.694e-277	872.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,47M84@768503|Cytophagia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD3_k127_1715629_38	700598.Niako_0353	2.089e-116	380.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
HKD3_k127_1715629_76	1392490.JHZX01000001_gene168	2.052e-24	112.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_1715629_7	925409.KI911562_gene2937	1.415e-295	917.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_1715629_70	1453505.JASY01000005_gene1510	2.372e-39	151.0	COG0824@1|root,COG0824@2|Bacteria,4NR2W@976|Bacteroidetes,1I43T@117743|Flavobacteriia,2NUI9@237|Flavobacterium	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
HKD3_k127_1715629_6	925409.KI911562_gene2246	3.03e-311	959.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1IPKK@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG0058 Glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
HKD3_k127_1715629_69	929556.Solca_3804	2.608e-42	158.0	COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,1IYB6@117747|Sphingobacteriia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
HKD3_k127_1715629_55	1267211.KI669560_gene1904	6.232e-67	235.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1IS2N@117747|Sphingobacteriia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD3_k127_1715629_32	866536.Belba_0068	1.173e-134	433.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,47NUB@768503|Cytophagia	976|Bacteroidetes	P	PFAM ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HKD3_k127_1715629_8	1123248.KB893337_gene2462	2.117e-279	867.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1IVXH@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HKD3_k127_1715629_2	925409.KI911562_gene1876	0.0	1161.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1IP8M@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
HKD3_k127_1715629_15	1267211.KI669560_gene2086	4.741e-197	620.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HKD3_k127_1715629_62	926549.KI421517_gene3195	8.359e-56	209.0	COG3386@1|root,COG3386@2|Bacteria,4NPTW@976|Bacteroidetes,47XR8@768503|Cytophagia	976|Bacteroidetes	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1715629_22	929556.Solca_1743	4.341e-172	546.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1IPKV@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD3_k127_1715629_39	1267211.KI669560_gene2692	5.114e-116	384.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IPHC@117747|Sphingobacteriia	976|Bacteroidetes	V	peptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD3_k127_1715629_0	929713.NIASO_00840	0.0	1611.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
HKD3_k127_1715629_25	1123248.KB893326_gene1397	1.2e-162	514.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
HKD3_k127_1715629_37	700598.Niako_0139	4.694e-122	397.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD3_k127_1715629_42	1123248.KB893326_gene1400	2.605e-98	327.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1IQDU@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD3_k127_1715629_1	1267211.KI669560_gene2528	0.0	1162.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
HKD3_k127_1715629_65	700598.Niako_3484	1.387e-48	178.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1ITU7@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
HKD3_k127_1715629_23	925409.KI911562_gene170	5.599e-169	541.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_1715629_10	700598.Niako_6993	8.788e-224	705.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1IQK8@117747|Sphingobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD3_k127_1715629_5	1267211.KI669560_gene2162	0.0	1041.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HKD3_k127_1715629_77	883096.HMPREF9699_00432	1.129e-17	96.0	COG2244@1|root,COG2244@2|Bacteria,4NRKF@976|Bacteroidetes,1I3V4@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_1715629_31	700598.Niako_2016	1.273e-141	456.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD3_k127_1715629_61	1123248.KB893337_gene2513	3.988e-57	212.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IQ1U@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
HKD3_k127_1715629_21	1237149.C900_03603	3.565e-174	568.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,47KE5@768503|Cytophagia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
HKD3_k127_1715629_57	714943.Mucpa_1617	3.313e-63	226.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1IS2C@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD3_k127_1715629_17	700598.Niako_1212	1.037e-189	599.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HKD3_k127_1715629_12	1267211.KI669560_gene1790	1.201e-214	672.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1IP2N@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein required for spore maturation in B.subtilis	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HKD3_k127_1715629_71	700598.Niako_0335	5.097e-37	143.0	COG2940@1|root,COG2940@2|Bacteria,4P66M@976|Bacteroidetes,1IYW5@117747|Sphingobacteriia	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD3_k127_1715629_28	925409.KI911562_gene2963	7.501e-154	495.0	COG2308@1|root,COG2308@2|Bacteria,4NG4D@976|Bacteroidetes,1IRDC@117747|Sphingobacteriia	976|Bacteroidetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1715629_56	925409.KI911562_gene1838	9.781e-64	225.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,1IP2M@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
HKD3_k127_1715629_49	925409.KI911562_gene1839	9.348e-92	306.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1IS2H@117747|Sphingobacteriia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
HKD3_k127_1715629_34	700598.Niako_5029	5.977e-125	413.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1IQKA@117747|Sphingobacteriia	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
HKD3_k127_1715629_20	700598.Niako_5028	1.314e-175	557.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1IQH3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_1715629_18	1089550.ATTH01000001_gene216	2.32e-184	586.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1FISV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD3_k127_1715629_16	1267211.KI669560_gene2360	8.659e-194	610.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1IPW2@117747|Sphingobacteriia	976|Bacteroidetes	GM	NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_1715629_14	1227739.Hsw_0078	1.504e-201	635.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,47JKM@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD3_k127_1715629_51	700598.Niako_5023	1.632e-85	292.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IP3S@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD3_k127_1715629_68	700598.Niako_4951	6.537e-45	181.0	COG0457@1|root,COG0457@2|Bacteria	700598.Niako_4951|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1715629_50	1313301.AUGC01000001_gene1687	1.085e-88	299.0	COG3751@1|root,COG3751@2|Bacteria,4NI8F@976|Bacteroidetes	976|Bacteroidetes	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
HKD3_k127_1715629_67	1408813.AYMG01000008_gene4040	4.763e-47	179.0	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,1IX9A@117747|Sphingobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_1715629_4	1267211.KI669560_gene1989	0.0	1148.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IQRG@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
HKD3_k127_1715629_13	714943.Mucpa_1472	2.397e-214	674.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1IPWD@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_1715629_40	700598.Niako_4928	1.694e-114	379.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
HKD3_k127_1715629_63	1267211.KI669560_gene595	1.324e-55	204.0	28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,1ISUV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1715629_29	700598.Niako_6995	1.985e-153	494.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,1J0KY@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1715629_54	1123248.KB893386_gene1963	3.606e-68	235.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,1IS13@117747|Sphingobacteriia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
HKD3_k127_1715629_60	929713.NIASO_11995	2.62e-58	205.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1ISB8@117747|Sphingobacteriia	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HKD3_k127_1715629_58	700598.Niako_6998	5.528e-63	225.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1ITXE@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
HKD3_k127_1715629_46	1123248.KB893386_gene1960	2.669e-93	322.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_1715629_24	1123248.KB893337_gene2596	3.378e-164	521.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1IP0K@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
HKD3_k127_1715629_43	925409.KI911562_gene1860	7.059e-98	328.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_1715629_48	925409.KI911562_gene2041	4.309e-92	319.0	COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,1IR2J@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_1715629_36	925409.KI911562_gene2042	3.121e-123	401.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1IPJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HKD3_k127_1715629_75	1123248.KB893329_gene4470	4.623e-30	123.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
HKD3_k127_1715629_3	1122176.KB903531_gene2876	0.0	1155.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD3_k127_1715629_47	1122605.KB893625_gene1797	7.827e-93	310.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1IRY5@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HKD3_k127_1715629_19	925409.KI911562_gene2960	7.029e-182	578.0	COG0761@1|root,COG0761@2|Bacteria	2|Bacteria	IM	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
HKD3_k127_1715629_11	1239962.C943_03564	1.573e-219	687.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,47XBR@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD3_k127_1715629_59	269798.CHU_1856	5.556e-63	224.0	2A19Z@1|root,30PGH@2|Bacteria,4PC2K@976|Bacteroidetes,47WQC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1715629_41	925409.KI911562_gene1822	3.105e-102	337.0	COG1428@1|root,COG1428@2|Bacteria,4PM5R@976|Bacteroidetes,1IXF2@117747|Sphingobacteriia	976|Bacteroidetes	F	Thymidylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD3_k127_1715629_66	929713.NIASO_20985	4.964e-48	177.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,1ISW1@117747|Sphingobacteriia	976|Bacteroidetes	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
HKD3_k127_1715629_26	1123248.KB893359_gene2069	4.164e-160	523.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
HKD3_k127_1715629_35	1123248.KB893359_gene2068	6.625e-125	411.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,1IQSZ@117747|Sphingobacteriia	976|Bacteroidetes	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD3_k127_171603_3	925409.KI911562_gene582	3.117e-25	105.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD3_k127_171603_1	700598.Niako_6592	4.2e-106	351.0	COG3637@1|root,COG3637@2|Bacteria,4NNPF@976|Bacteroidetes,1ISTC@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_171603_0	1267211.KI669560_gene284	5.212e-124	403.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HKD3_k127_171603_2	925409.KI911562_gene897	1.763e-61	222.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,1IWQ4@117747|Sphingobacteriia	976|Bacteroidetes	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD3_k127_1718558_30	1403946.Q615_SPAC00010G0001	3.669e-11	65.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,4HYZ4@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1718558_8	1123248.KB893314_gene3588	1.562e-148	473.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_1718558_26	1237149.C900_02632	1.003e-29	121.0	COG4095@1|root,COG4095@2|Bacteria	2|Bacteria	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
HKD3_k127_1718558_24	700598.Niako_5479	1.297e-40	151.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,1ITH1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
HKD3_k127_1718558_16	700598.Niako_5478	7.421e-87	293.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
HKD3_k127_1718558_18	925409.KI911562_gene96	2.344e-81	276.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1IRY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HKD3_k127_1718558_11	1123248.KB893359_gene2117	2.711e-115	375.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_1718558_28	1123248.KB893359_gene2118	6.911e-25	108.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1ITUB@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HKD3_k127_1718558_12	1379270.AUXF01000004_gene2906	1.53e-112	379.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	adiC	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_1718558_14	1379270.AUXF01000007_gene997	5.645e-93	319.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_1718558_4	700598.Niako_7085	1.168e-184	589.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1IPFD@117747|Sphingobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HKD3_k127_1718558_13	925409.KI911562_gene1315	2.391e-97	325.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HKD3_k127_1718558_19	1267211.KI669560_gene970	8.711e-73	249.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD3_k127_1718558_20	925409.KI911562_gene1313	4.257e-67	235.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,1IRXT@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD3_k127_1718558_10	700598.Niako_7078	4.526e-134	432.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HKD3_k127_1718558_0	700598.Niako_7077	4.082e-292	921.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD3_k127_1718558_22	391603.FBALC1_10707	2.101e-52	197.0	COG0657@1|root,COG0657@2|Bacteria,4NFTX@976|Bacteroidetes,1I0SN@117743|Flavobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HKD3_k127_1718558_9	1123248.KB893330_gene398	2.252e-147	479.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_1718558_6	700598.Niako_7075	6.518e-165	530.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HKD3_k127_1718558_5	1267211.KI669560_gene963	1.442e-173	556.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HKD3_k127_1718558_1	925409.KI911562_gene202	2.523e-272	850.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
HKD3_k127_1718558_23	1267211.KI669560_gene961	7.62e-43	159.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1ITKQ@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HKD3_k127_1718558_21	700598.Niako_7071	8.228e-58	206.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1ISVB@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HKD3_k127_1718558_15	1123248.KB893314_gene3393	5.98e-93	308.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1IS7C@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
HKD3_k127_1718558_7	1123248.KB893314_gene3394	4.536e-162	516.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1IR49@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HKD3_k127_1718558_3	1122605.KB893644_gene1411	1.528e-197	619.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
HKD3_k127_1718558_31	1123508.JH636446_gene6270	8.308e-09	66.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_24,TylF
HKD3_k127_1718558_2	700598.Niako_7067	1.446e-271	838.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HKD3_k127_1718558_27	113355.CM001775_gene2581	2.877e-29	122.0	COG3015@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,NlpE
HKD3_k127_1718558_17	700598.Niako_7066	1.124e-84	282.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1IS1Q@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HKD3_k127_1718558_25	925409.KI911562_gene211	2.492e-31	122.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR4T@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
HKD3_k127_1744500_2	700598.Niako_1547	3.176e-72	246.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1INM8@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HKD3_k127_1744500_0	925409.KI911562_gene2649	4.282e-291	919.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_1744500_3	1185876.BN8_01684	2.199e-30	134.0	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,47P9G@768503|Cytophagia	976|Bacteroidetes	M	PFAM Fasciclin domain	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	Fasciclin
HKD3_k127_1744500_1	700598.Niako_1591	8.981e-107	349.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD3_k127_1830868_2	1279009.ADICEAN_03772	5.49e-21	98.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,47N5M@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the ABC transporter superfamily	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
HKD3_k127_1830868_1	1111730.ATTM01000006_gene2632	5.839e-39	154.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia,2NYSA@237|Flavobacterium	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
HKD3_k127_1830868_0	700598.Niako_3552	6.134e-186	595.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IVSZ@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0553 Superfamily II DNA RNA helicase SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
HKD3_k127_1850328_0	925409.KI911562_gene2343	1.925e-166	534.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_1850328_2	714943.Mucpa_6353	7.444e-28	119.0	2CK2Y@1|root,32SBF@2|Bacteria,4NTZD@976|Bacteroidetes,1ITGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Photosynthetic reaction centre cytochrome C subunit	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	CytoC_RC
HKD3_k127_1850328_1	700598.Niako_3093	2.081e-32	127.0	COG3279@1|root,COG3279@2|Bacteria,4NIXU@976|Bacteroidetes,1IRCD@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_1861989_2	1123248.KB893370_gene5145	6.517e-114	370.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1IPSQ@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01965,ko:K01968	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00373,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_1861989_0	1123248.KB893370_gene5144	1.395e-296	915.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IQ23@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD3_k127_1861989_1	1123248.KB893315_gene3223	2.524e-131	426.0	COG3291@1|root,COG3291@2|Bacteria,4NH7R@976|Bacteroidetes,1IWQY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_1861989_3	760192.Halhy_4898	5.666e-52	186.0	COG3250@1|root,COG3867@1|root,COG3250@2|Bacteria,COG3867@2|Bacteria,4NEWN@976|Bacteroidetes,1IRAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_1870419_2	1433126.BN938_3032	7.988e-67	234.0	2CB8B@1|root,33HNV@2|Bacteria,4NZ1I@976|Bacteroidetes,2FXDG@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1870419_0	700598.Niako_3663	6.902e-113	376.0	COG1609@1|root,COG1609@2|Bacteria,4NFB7@976|Bacteroidetes,1IRES@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
HKD3_k127_1870419_1	1122605.KB893628_gene4395	1.087e-90	307.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,1INWR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Bacterial alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
HKD3_k127_1884864_2	313606.M23134_06773	2.178e-90	313.0	COG2911@1|root,COG3291@1|root,COG4447@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4NI13@976|Bacteroidetes,47NV6@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_1884864_7	700598.Niako_3423	1.682e-49	184.0	COG3897@1|root,COG3897@2|Bacteria,4P696@976|Bacteroidetes,1IZ1E@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
HKD3_k127_1884864_0	880073.Calab_0178	9.638e-158	505.0	COG3191@1|root,COG3191@2|Bacteria,2NNR0@2323|unclassified Bacteria	2|Bacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
HKD3_k127_1884864_3	1123248.KB893348_gene284	1.141e-83	283.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,1IY3D@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
HKD3_k127_1884864_9	925409.KI911562_gene452	7.826e-18	89.0	COG5652@1|root,COG5652@2|Bacteria,4NXUQ@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD3_k127_1884864_8	700598.Niako_5746	1.279e-22	106.0	COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,1IS07@117747|Sphingobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
HKD3_k127_1884864_5	700598.Niako_5748	2.444e-57	201.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IXRK@117747|Sphingobacteriia	976|Bacteroidetes	E	Glycine cleavage H-protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
HKD3_k127_1884864_4	388413.ALPR1_16883	1.382e-78	269.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	PKD,Pro_isomerase
HKD3_k127_1884864_6	925409.KI911562_gene450	1.607e-50	182.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1ISQF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1884864_1	1122605.KB893626_gene2754	5.131e-108	357.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD3_k127_1902846_0	925409.KI911562_gene211	2.974e-236	734.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR4T@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
HKD3_k127_1902846_3	925409.KI911562_gene212	6.254e-81	272.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1ISEW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HKD3_k127_1902846_2	925409.KI911562_gene213	7.071e-103	336.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HKD3_k127_1902846_4	1267211.KI669560_gene951	2.052e-55	196.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1ISVI@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HKD3_k127_1902846_1	1123248.KB893381_gene1014	3.42e-104	360.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IPR2@117747|Sphingobacteriia	976|Bacteroidetes	NU	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HKD3_k127_1902846_5	700598.Niako_7059	1.314e-36	141.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes	976|Bacteroidetes	P	Phosphate ABC transporter substrate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD3_k127_1989653_1	485917.Phep_3638	1.338e-50	184.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1INUX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_1989653_2	485918.Cpin_2868	1.151e-38	151.0	COG0727@1|root,COG0727@2|Bacteria,4P5VP@976|Bacteroidetes	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD3_k127_1989653_0	925409.KI911562_gene2149	4.885e-70	243.0	COG2910@1|root,COG2910@2|Bacteria,4PP94@976|Bacteroidetes,1IYBJ@117747|Sphingobacteriia	976|Bacteroidetes	S	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
HKD3_k127_1989653_4	925409.KI911562_gene2150	2.243e-36	140.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1ITHB@117747|Sphingobacteriia	976|Bacteroidetes	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
HKD3_k127_1989653_3	929556.Solca_0791	1.74e-37	142.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_2064766_4	1267211.KI669560_gene1337	3.756e-197	618.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1IPEC@117747|Sphingobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HKD3_k127_2064766_6	1123248.KB893314_gene3304	2.878e-128	415.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1IP59@117747|Sphingobacteriia	976|Bacteroidetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD3_k127_2064766_11	1122605.KB893647_gene486	1.79e-28	124.0	2DQH4@1|root,336TE@2|Bacteria,4NXA3@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
HKD3_k127_2064766_5	1123248.KB893326_gene1494	1.09e-184	582.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HKD3_k127_2064766_0	867902.Ornrh_0091	0.0	1360.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HKD3_k127_2064766_2	925409.KI911562_gene1624	1.427e-219	689.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPMC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD3_k127_2064766_9	925409.KI911562_gene1625	1.893e-85	290.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1ISNC@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HKD3_k127_2064766_12	929713.NIASO_03100	6.105e-28	114.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1ITNI@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
HKD3_k127_2064766_7	925409.KI911562_gene1627	1.47e-105	346.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1IPC1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD3_k127_2064766_8	1313301.AUGC01000005_gene235	5.415e-92	307.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD3_k127_2064766_1	1267211.KI669560_gene1375	2.266e-254	798.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IX27@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_2064766_3	867902.Ornrh_1424	2.874e-207	662.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208,ko:K21575	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N,DUF3459
HKD3_k127_2064766_13	411477.PARMER_02824	9.389e-25	114.0	2E380@1|root,32Y7Q@2|Bacteria,4NN04@976|Bacteroidetes,2FM58@200643|Bacteroidia,22YHN@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_2064766_10	1267211.KI669560_gene1376	2.087e-79	271.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1IR77@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HKD3_k127_209007_0	1288963.ADIS_1506	1.242e-226	718.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_209007_1	1492737.FEM08_29200	1.269e-190	610.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_209007_2	700598.Niako_3759	1.083e-55	196.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1IQJ7@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_2099006_1	1089547.KB913013_gene4724	1.115e-31	132.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	DUF11,DUF4114,DUF4347,He_PIG,PBP_like_2,PKD,SLH,SdrD_B,VCBS
HKD3_k127_2099006_0	1089547.KB913013_gene4724	8.872e-244	778.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	DUF11,DUF4114,DUF4347,He_PIG,PBP_like_2,PKD,SLH,SdrD_B,VCBS
HKD3_k127_2132577_1	945713.IALB_0990	1.378e-92	310.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_2132577_2	485918.Cpin_0241	2.94e-66	228.0	COG2185@1|root,COG2185@2|Bacteria,4NNXP@976|Bacteroidetes	976|Bacteroidetes	I	TIGRFAM methylmalonyl-CoA mutase C-terminal domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
HKD3_k127_2132577_3	929713.NIASO_09270	3.99e-44	169.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes	976|Bacteroidetes	S	cytochrome c biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
HKD3_k127_2132577_4	1313421.JHBV01000030_gene2076	1.964e-21	99.0	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes	976|Bacteroidetes	P	cytochrome cbb3 oxidase maturation protein CcoH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
HKD3_k127_2132577_0	700598.Niako_1944	3.458e-111	366.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
HKD3_k127_2143266_7	925409.KI911562_gene925	1.078e-12	69.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1INUR@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
HKD3_k127_2143266_2	925409.KI911562_gene926	1.253e-161	516.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HKD3_k127_2143266_6	1120966.AUBU01000003_gene1360	4.762e-35	138.0	COG4270@1|root,COG4270@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,DoxX_2
HKD3_k127_2143266_3	700598.Niako_6413	1.917e-159	520.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1IP0R@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_2143266_1	925409.KI911562_gene2742	2.624e-166	529.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1IPZU@117747|Sphingobacteriia	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
HKD3_k127_2143266_5	925409.KI911562_gene2743	8.86e-51	182.0	COG0745@1|root,COG0745@2|Bacteria,4NQ69@976|Bacteroidetes,1ISWK@117747|Sphingobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HKD3_k127_2143266_4	388413.ALPR1_02200	3.986e-113	392.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47NSI@768503|Cytophagia	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA
HKD3_k127_2143266_0	1239962.C943_00057	2.218e-273	878.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
HKD3_k127_2192399_3	1007104.SUS17_3290	1.086e-12	70.0	COG3537@1|root,COG3537@2|Bacteria,1N86N@1224|Proteobacteria,2UNRF@28211|Alphaproteobacteria,2K2DH@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_2192399_0	925409.KI911562_gene2236	0.0	1074.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1IPSI@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
HKD3_k127_2192399_1	485917.Phep_2995	3.023e-107	361.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IQ0I@117747|Sphingobacteriia	976|Bacteroidetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
HKD3_k127_2230398_0	1220589.CD32_10555	9.463e-99	331.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,3IZ1A@400634|Lysinibacillus	91061|Bacilli	P	Natural resistance-associated macrophage protein	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_2230398_1	1341181.FLJC2902T_21090	4.042e-72	265.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4P772@976|Bacteroidetes,1IBXR@117743|Flavobacteriia,2NWQB@237|Flavobacterium	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SprB
HKD3_k127_2255310_2	395493.BegalDRAFT_1353	6.108e-36	152.0	COG1680@1|root,COG1680@2|Bacteria,1PF8A@1224|Proteobacteria,1SWQW@1236|Gammaproteobacteria,462UZ@72273|Thiotrichales	72273|Thiotrichales	V	PFAM beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
HKD3_k127_2255310_4	997829.HMPREF1121_01509	1.108e-06	58.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,23235@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_2255310_0	1267211.KI669560_gene2813	1.017e-307	946.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD3_k127_2255310_3	880071.Fleli_1113	5.505e-09	70.0	COG4935@1|root,COG4935@2|Bacteria,4NRQR@976|Bacteroidetes,47YIE@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2255310_5	700598.Niako_6907	3.886e-06	60.0	COG3170@1|root,COG3291@1|root,COG3170@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.3.3,3.5.1.28	ko:K01448,ko:K07315,ko:K21470	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03021,ko03036	-	-	-	CHU_C,PKD
HKD3_k127_2255310_1	1121904.ARBP01000001_gene5820	4.504e-114	378.0	COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,47UEF@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
HKD3_k127_227714_1	925409.KI911562_gene1720	2.074e-149	481.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1IV3Y@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_227714_0	1123248.KB893315_gene3012	6.363e-275	858.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HKD3_k127_229165_0	1166018.FAES_4751	2.616e-229	728.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NHSI@976|Bacteroidetes,47NR1@768503|Cytophagia	976|Bacteroidetes	DM	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR
HKD3_k127_229165_5	1227739.Hsw_PA0140	7.899e-38	157.0	COG2244@1|root,COG2244@2|Bacteria,4NU8G@976|Bacteroidetes,47RH3@768503|Cytophagia	976|Bacteroidetes	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_229165_3	1166018.FAES_4753	3.251e-102	344.0	COG0438@1|root,COG0438@2|Bacteria,4NN2B@976|Bacteroidetes,47PA1@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_229165_2	1166018.FAES_4754	3.475e-200	632.0	COG3307@1|root,COG3307@2|Bacteria,4NHN0@976|Bacteroidetes,47M85@768503|Cytophagia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HKD3_k127_229165_1	1166018.FAES_4755	1.66e-210	681.0	COG0125@1|root,COG0510@1|root,COG0125@2|Bacteria,COG0510@2|Bacteria,4NKEA@976|Bacteroidetes,47NV8@768503|Cytophagia	976|Bacteroidetes	FM	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_229165_4	1166018.FAES_4756	6.64e-95	316.0	COG0110@1|root,COG0110@2|Bacteria,4NRD8@976|Bacteroidetes,47PJX@768503|Cytophagia	976|Bacteroidetes	S	Acetyltransferase (Isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
HKD3_k127_229165_6	1166018.FAES_4757	1.496e-22	98.0	COG0438@1|root,COG0438@2|Bacteria,4NHUT@976|Bacteroidetes,47P33@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD3_k127_2417242_0	925409.KI911562_gene1195	0.0	1167.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD3_k127_2417242_3	929713.NIASO_06440	3.772e-60	209.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Chaperonin Cpn10	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
HKD3_k127_2417242_1	925409.KI911562_gene1225	3.301e-135	432.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1IP15@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_2417242_5	269798.CHU_1426	1.7e-32	130.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,47R0R@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD3_k127_2417242_2	1121904.ARBP01000001_gene5403	9.546e-103	340.0	COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,47P2E@768503|Cytophagia	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	vat_2	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
HKD3_k127_2417242_4	391587.KAOT1_20227	1.986e-47	176.0	COG2318@1|root,COG2318@2|Bacteria,4NP2K@976|Bacteroidetes,1I2CD@117743|Flavobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_2427326_5	700598.Niako_5157	1.398e-69	239.0	COG3427@1|root,COG3427@2|Bacteria,4NRMQ@976|Bacteroidetes	2|Bacteria	S	PFAM Carbon monoxide dehydrogenase subunit G (CoxG)	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
HKD3_k127_2427326_3	700598.Niako_5156	2.275e-139	449.0	COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes,1IW28@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ATPase associated with various cellular activities AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
HKD3_k127_2427326_1	700598.Niako_5155	3.163e-159	509.0	COG3552@1|root,COG3552@2|Bacteria,4NK40@976|Bacteroidetes,1IWRV@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
HKD3_k127_2427326_6	1123228.AUIH01000004_gene1087	5.81e-67	240.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,1MWFN@1224|Proteobacteria,1RV4F@1236|Gammaproteobacteria,1XQ7H@135619|Oceanospirillales	135619|Oceanospirillales	O	XdhC Rossmann domain	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
HKD3_k127_2427326_0	700598.Niako_5153	7.719e-187	591.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HKD3_k127_2427326_7	714943.Mucpa_5087	3.318e-47	176.0	COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes,1ISZY@117747|Sphingobacteriia	976|Bacteroidetes	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HKD3_k127_2427326_2	700598.Niako_0551	5.68e-151	483.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1IPUJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HKD3_k127_2427326_4	485918.Cpin_4133	1.344e-110	366.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IWJE@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_2430076_1	1185876.BN8_00315	2.178e-66	239.0	COG3391@1|root,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes	976|Bacteroidetes	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2430076_0	1239962.C943_00420	1.106e-92	331.0	COG0457@1|root,COG0457@2|Bacteria,4P3C6@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2430076_2	655815.ZPR_2098	6.138e-13	81.0	COG5295@1|root,COG5295@2|Bacteria,4NN7P@976|Bacteroidetes,1I1GH@117743|Flavobacteriia	976|Bacteroidetes	UW	Head domain of trimeric autotransporter adhesin	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	YadA_head
HKD3_k127_2432078_3	1453505.JASY01000002_gene2349	3.389e-64	221.0	COG2308@1|root,COG2308@2|Bacteria,4NFMN@976|Bacteroidetes,1HXQ6@117743|Flavobacteriia,2NU8C@237|Flavobacterium	976|Bacteroidetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
HKD3_k127_2432078_2	1144313.PMI10_02610	1.391e-104	348.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1I040@117743|Flavobacteriia,2NUS5@237|Flavobacterium	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HKD3_k127_2432078_1	485918.Cpin_5583	1.373e-115	380.0	COG1305@1|root,COG1305@2|Bacteria,4NF4N@976|Bacteroidetes,1IPWA@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG1305 Transglutaminase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
HKD3_k127_2432078_0	1267211.KI669560_gene1276	9.629e-194	613.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD3_k127_2438069_1	700598.Niako_4507	3.884e-173	545.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD3_k127_2438069_5	929713.NIASO_01130	5.933e-113	375.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1IQ2Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD3_k127_2438069_3	1122605.KB893625_gene2000	4.536e-146	479.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1IQJK@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HKD3_k127_2438069_2	925409.KI911562_gene2792	1.122e-166	534.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1IQ18@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HKD3_k127_2438069_4	700598.Niako_0920	4.26e-135	437.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_2438069_0	760192.Halhy_2129	6.737e-251	785.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
HKD3_k127_2438069_6	1123248.KB893316_gene4638	5.038e-36	139.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1IP9N@117747|Sphingobacteriia	976|Bacteroidetes	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
HKD3_k127_2443978_1	700598.Niako_1029	3.956e-94	314.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IWD6@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_2443978_2	1122605.KB893637_gene3103	5.213e-42	166.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,1IRY7@117747|Sphingobacteriia	976|Bacteroidetes	M	Nlp p60 protein	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HKD3_k127_2443978_0	1267211.KI669560_gene1821	8.298e-272	841.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD3_k127_2448196_2	471854.Dfer_2431	9.562e-26	108.0	2DQR8@1|root,33877@2|Bacteria,4NWHC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2448196_1	1122605.KB893629_gene4169	5.206e-200	637.0	COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1IP90@117747|Sphingobacteriia	976|Bacteroidetes	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
HKD3_k127_2448196_0	485918.Cpin_0917	2.354e-232	721.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IPSM@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD3_k127_2450514_7	1121875.KB907555_gene347	3.605e-22	98.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HZ9K@117743|Flavobacteriia	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_2450514_1	1120968.AUBX01000011_gene2998	2.054e-159	522.0	COG1435@1|root,COG1435@2|Bacteria,4NE0S@976|Bacteroidetes,47K26@768503|Cytophagia	976|Bacteroidetes	F	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_2450514_0	1380600.AUYN01000001_gene2796	2.167e-257	832.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HZS7@117743|Flavobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_2450514_3	925409.KI911562_gene984	6.576e-88	304.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,1IV3Q@117747|Sphingobacteriia	976|Bacteroidetes	PT	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_2450514_5	1122605.KB893625_gene1892	3.278e-33	137.0	COG1595@1|root,COG1595@2|Bacteria,4NSRK@976|Bacteroidetes,1ITS7@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_2450514_9	1150600.ADIARSV_4214	0.0002345	49.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NEXG@976|Bacteroidetes,1IPN6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
HKD3_k127_2450514_4	471870.BACINT_02328	1.633e-34	134.0	COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,2FT3R@200643|Bacteroidia,4ARM3@815|Bacteroidaceae	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_2450514_6	746697.Aeqsu_1377	2.217e-31	127.0	COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes,1I4GX@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
HKD3_k127_2450514_2	504472.Slin_2753	2.665e-144	465.0	COG1231@1|root,COG1231@2|Bacteria,4NGST@976|Bacteroidetes,47MNA@768503|Cytophagia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
HKD3_k127_2464650_3	1279009.ADICEAN_01721	1.083e-64	228.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia	976|Bacteroidetes	H	MoeZ MoeB domain	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HKD3_k127_2464650_2	700598.Niako_0554	2.752e-68	236.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1ITHC@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
HKD3_k127_2464650_1	700598.Niako_0555	4.552e-132	428.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1INZV@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
HKD3_k127_2464650_4	1123248.KB893318_gene4148	4.88e-29	133.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_2464650_0	1304284.L21TH_2037	2.886e-159	513.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36DWE@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HKD3_k127_2465555_0	760192.Halhy_0367	6.026e-187	594.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1IQAK@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
HKD3_k127_2465555_2	694427.Palpr_1487	1.137e-30	123.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,2FMH5@200643|Bacteroidia,22X85@171551|Porphyromonadaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD3_k127_2468654_8	485918.Cpin_5478	9.442e-64	227.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_2468654_1	1267211.KI669560_gene2012	1.679e-233	747.0	COG1629@1|root,COG1629@2|Bacteria,4NMUQ@976|Bacteroidetes,1IS0V@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_2468654_3	1267211.KI669560_gene2447	1.653e-145	468.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1IQTZ@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD3_k127_2468654_5	925409.KI911562_gene1669	3.148e-91	304.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1IQAP@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HKD3_k127_2468654_10	1123248.KB893320_gene3932	4.661e-38	146.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
HKD3_k127_2468654_6	485918.Cpin_4038	4.462e-86	292.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,1ISCN@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD3_k127_2468654_4	700598.Niako_0381	2.234e-115	378.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1IQGT@117747|Sphingobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_2468654_2	925409.KI911562_gene2961	2.719e-186	603.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1ISVQ@117747|Sphingobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
HKD3_k127_2468654_7	1122605.KB893625_gene1580	9.044e-67	241.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1ISCP@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
HKD3_k127_2468654_9	313606.M23134_01106	7.323e-50	183.0	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,47QB7@768503|Cytophagia	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
HKD3_k127_2468654_11	925409.KI911562_gene2881	8.439e-35	138.0	2EWYR@1|root,346M6@2|Bacteria,4P5DU@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
HKD3_k127_2468654_0	1123248.KB893337_gene2458	5.18e-234	735.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IX43@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
HKD3_k127_2480987_2	1089547.KB913013_gene3929	1.001e-23	101.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,47MUJ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD3_k127_2480987_0	324925.Ppha_1183	1.02e-174	557.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_2480987_1	641524.ADICYQ_2398	3.602e-81	289.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,47MZE@768503|Cytophagia	976|Bacteroidetes	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
HKD3_k127_2513953_5	1033734.CAET01000079_gene3677	4.249e-05	47.0	2DIA4@1|root,302HW@2|Bacteria,1U5Y3@1239|Firmicutes,4IM9X@91061|Bacilli,1ZJJZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2513953_1	700598.Niako_5147	3.521e-190	597.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IUYE@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_2513953_0	925409.KI911562_gene22	1.876e-199	627.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HKD3_k127_2513953_3	929713.NIASO_10735	7.975e-64	227.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1IQC4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
HKD3_k127_2513953_2	485918.Cpin_0141	3.768e-73	255.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,1IPTU@117747|Sphingobacteriia	976|Bacteroidetes	S	MOSC domain containing protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
HKD3_k127_2513953_4	700598.Niako_5270	4.294e-48	177.0	COG2050@1|root,COG2050@2|Bacteria,4NNXM@976|Bacteroidetes,1IY7V@117747|Sphingobacteriia	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
HKD3_k127_2513953_6	1279009.ADICEAN_02998	0.0001812	47.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,47JC7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2515638_17	1250278.JQNQ01000001_gene2748	7.272e-06	54.0	COG1266@1|root,COG1266@2|Bacteria,4NHRW@976|Bacteroidetes,1I1CE@117743|Flavobacteriia	976|Bacteroidetes	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_2515638_3	925409.KI911562_gene1584	2.141e-190	602.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1INZR@117747|Sphingobacteriia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_2515638_5	1123248.KB893386_gene1888	5.266e-150	489.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1IVHN@117747|Sphingobacteriia	976|Bacteroidetes	P	COG1055 Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
HKD3_k127_2515638_7	926549.KI421517_gene1934	3.076e-83	286.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2515638_9	700598.Niako_1210	1.892e-67	234.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1ITP3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2515638_10	1122605.KB893625_gene1861	1.166e-52	186.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD3_k127_2515638_4	700598.Niako_1014	3.408e-163	525.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1IWRU@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD3_k127_2515638_6	700598.Niako_0411	9.84e-95	317.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,1IPA5@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_2515638_1	1122605.KB893649_gene3873	2.721e-281	887.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IP26@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_2515638_2	1235813.JCM10003_1599	9.584e-191	599.0	COG2152@1|root,COG2152@2|Bacteria,4NGI7@976|Bacteroidetes,2FMV9@200643|Bacteroidia,4AK8Y@815|Bacteroidaceae	976|Bacteroidetes	G	glycosylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
HKD3_k127_2515638_13	509635.N824_21960	6.664e-26	116.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1IU8K@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_2515638_0	1267211.KI669560_gene1815	1.896e-305	951.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1IP8R@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD3_k127_2515638_15	1267211.KI669560_gene1803	1.42e-10	68.0	2DFDT@1|root,2ZRHG@2|Bacteria,4P6Y0@976|Bacteroidetes,1J02T@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2515638_8	485918.Cpin_4294	2.286e-71	246.0	COG2197@1|root,COG2197@2|Bacteria,4P2TZ@976|Bacteroidetes,1IXGA@117747|Sphingobacteriia	976|Bacteroidetes	K	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2515638_12	761193.Runsl_2864	1.484e-41	164.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,47PFT@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
HKD3_k127_2515638_16	1185876.BN8_04379	5.025e-10	70.0	COG2197@1|root,COG2197@2|Bacteria,4NSGV@976|Bacteroidetes,47UC0@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2515638_11	1408433.JHXV01000022_gene3175	1.343e-46	188.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD3_k127_2515638_14	1484460.JSWG01000015_gene1033	1.894e-19	103.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG2866@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2866@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,SprB,TSP_3
HKD3_k127_2553326_0	1121904.ARBP01000003_gene6255	3.141e-177	580.0	COG4206@1|root,COG4206@2|Bacteria,4PKFW@976|Bacteroidetes,47Y2Y@768503|Cytophagia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD3_k127_2553326_1	485918.Cpin_3938	4.543e-173	546.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IPIY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	pabB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
HKD3_k127_2553326_2	700598.Niako_4381	1.075e-20	93.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1IP6F@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
HKD3_k127_255380_4	1121912.AUHD01000001_gene2743	6.045e-05	46.0	COG4538@1|root,COG4538@2|Bacteria,4PKKQ@976|Bacteroidetes,1HYE5@117743|Flavobacteriia	976|Bacteroidetes	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SnoaL_2
HKD3_k127_255380_2	700598.Niako_1570	4.04e-61	223.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,1IS3N@117747|Sphingobacteriia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
HKD3_k127_255380_1	925409.KI911562_gene2138	6.6e-119	386.0	COG1179@1|root,COG1179@2|Bacteria,4NEKB@976|Bacteroidetes,1IPIM@117747|Sphingobacteriia	976|Bacteroidetes	H	ThiF family	tcdA	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
HKD3_k127_255380_0	700598.Niako_0885	0.0	1026.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1IQV0@117747|Sphingobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_255380_3	925409.KI911562_gene2266	1.2e-35	139.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5I@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
HKD3_k127_2584494_10	929556.Solca_3217	6.059e-65	232.0	28JKB@1|root,2Z9D6@2|Bacteria,4NJC1@976|Bacteroidetes,1IRBG@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2584494_6	1122605.KB893629_gene4089	1.871e-101	361.0	2DB7X@1|root,2Z7P2@2|Bacteria,4NH95@976|Bacteroidetes,1J0CX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2584494_19	1121895.Q765_20235	0.0002243	51.0	COG4319@1|root,COG4319@2|Bacteria,4NPHQ@976|Bacteroidetes,1IN3T@117743|Flavobacteriia,2NX8T@237|Flavobacterium	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2584494_3	929713.NIASO_15495	9.099e-120	390.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1IPN9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_2584494_7	700598.Niako_2187	4.161e-101	338.0	COG5285@1|root,COG5285@2|Bacteria,4NMHK@976|Bacteroidetes,1IX1R@117747|Sphingobacteriia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
HKD3_k127_2584494_0	925409.KI911562_gene730	1.237e-243	761.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,1J0QZ@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_2584494_11	925409.KI911562_gene2976	1.996e-55	202.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_2584494_4	925409.KI911562_gene2974	1.983e-113	386.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,1IQNH@117747|Sphingobacteriia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
HKD3_k127_2584494_9	925409.KI911562_gene867	5.228e-85	288.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD3_k127_2584494_13	886379.AEWI01000013_gene2105	1.441e-38	147.0	COG2337@1|root,COG2337@2|Bacteria,4NRIX@976|Bacteroidetes	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HKD3_k127_2584494_16	866536.Belba_2374	2.65e-16	84.0	2EA6H@1|root,334B9@2|Bacteria,4NUWX@976|Bacteroidetes,47X36@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2584494_5	925409.KI911562_gene868	3.279e-110	361.0	COG4947@1|root,COG4947@2|Bacteria,4NJWM@976|Bacteroidetes,1IVCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_2584494_14	1122605.KB893643_gene532	2.182e-38	153.0	2C85M@1|root,31482@2|Bacteria,4NSY2@976|Bacteroidetes,1IUAG@117747|Sphingobacteriia	976|Bacteroidetes	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
HKD3_k127_2584494_12	1123248.KB893322_gene575	3.722e-55	194.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1ITCV@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HKD3_k127_2584494_15	700598.Niako_5598	2.01e-27	113.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IUFV@117747|Sphingobacteriia	976|Bacteroidetes	U	Sec-independent protein translocase protein TatA	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HKD3_k127_2584494_1	485918.Cpin_1333	9.712e-179	572.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IQR9@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HKD3_k127_2584494_8	925409.KI911562_gene1188	6.973e-100	338.0	COG0741@1|root,COG0741@2|Bacteria,4NEKW@976|Bacteroidetes,1IRNH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
HKD3_k127_2584494_2	700598.Niako_5601	2.545e-135	443.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1IPYM@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM chorismate binding	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD3_k127_2591119_3	1123248.KB893348_gene249	1.642e-54	195.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
HKD3_k127_2591119_0	700598.Niako_5110	1.55e-142	463.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1IPJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD3_k127_2591119_4	925409.KI911562_gene3008	1.247e-45	167.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1ISVJ@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
HKD3_k127_2591119_1	1123248.KB893348_gene246	3.767e-92	313.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
HKD3_k127_2591119_2	700598.Niako_5113	5.804e-92	310.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD3_k127_2591119_5	485918.Cpin_6987	5.445e-43	168.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD3_k127_259914_3	1121957.ATVL01000010_gene597	1.107e-42	160.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,47NNC@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_259914_2	700598.Niako_4625	8.755e-105	352.0	COG2114@1|root,COG2207@1|root,COG2114@2|Bacteria,COG2207@2|Bacteria,4NFVC@976|Bacteroidetes,1IXZX@117747|Sphingobacteriia	976|Bacteroidetes	K	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242,HTH_18
HKD3_k127_259914_4	313603.FB2170_11691	8.821e-42	157.0	2C82G@1|root,32RK9@2|Bacteria,4NSXV@976|Bacteroidetes,1I466@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
HKD3_k127_259914_1	700598.Niako_5688	1.044e-107	353.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IR6P@117747|Sphingobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_259914_0	925409.KI911562_gene429	2.438e-131	422.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD3_k127_2599251_3	1267211.KI669560_gene2010	3.02e-36	138.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1IP0Z@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
HKD3_k127_2599251_1	929713.NIASO_03045	1.174e-111	372.0	COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes	976|Bacteroidetes	HJ	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	RimK
HKD3_k127_2599251_2	1122605.KB893625_gene1792	2.679e-63	224.0	COG1280@1|root,COG1280@2|Bacteria,4NUV7@976|Bacteroidetes,1IUGQ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_2599251_0	1239962.C943_00701	4.716e-116	383.0	COG4313@1|root,COG4313@2|Bacteria,4NS24@976|Bacteroidetes	976|Bacteroidetes	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
HKD3_k127_2599570_0	929703.KE386491_gene113	4.94e-316	988.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD3_k127_2599570_16	700598.Niako_4539	2.436e-50	189.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1ISK8@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
HKD3_k127_2599570_12	700598.Niako_4538	8.136e-81	276.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
HKD3_k127_2599570_17	700598.Niako_4537	5.876e-41	157.0	COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,1ITRS@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
HKD3_k127_2599570_1	925409.KI911562_gene2578	7.588e-248	770.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1IQY7@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_2599570_4	485918.Cpin_1665	5.316e-203	646.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1IQXH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD3_k127_2599570_10	1123248.KB893323_gene1653	6.404e-95	319.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
HKD3_k127_2599570_8	1123248.KB893337_gene2381	1.237e-148	484.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1IRU6@117747|Sphingobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_2599570_9	1123248.KB893337_gene2382	3.24e-134	441.0	COG1566@1|root,COG1566@2|Bacteria,4PM5Z@976|Bacteroidetes,1J0IM@117747|Sphingobacteriia	976|Bacteroidetes	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
HKD3_k127_2599570_7	468059.AUHA01000002_gene1344	1.4e-177	572.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1IQD5@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
HKD3_k127_2599570_15	1123248.KB893348_gene170	2.538e-51	192.0	2E602@1|root,330PE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2599570_3	1267211.KI669560_gene1988	1.799e-232	722.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_2599570_11	1121288.AULL01000019_gene1479	2.628e-81	293.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HZJX@117743|Flavobacteriia,3ZUJA@59732|Chryseobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
HKD3_k127_2599570_13	1267211.KI669560_gene1981	8.787e-59	212.0	COG2197@1|root,COG2197@2|Bacteria,4NQVA@976|Bacteroidetes	976|Bacteroidetes	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2599570_6	1121287.AUMU01000006_gene3737	4.299e-198	632.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia,3ZQ56@59732|Chryseobacterium	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD3_k127_2599570_18	573061.Clocel_2179	1.454e-12	78.0	2E676@1|root,330VQ@2|Bacteria,1VCQS@1239|Firmicutes,24XF0@186801|Clostridia,36P42@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2599570_2	1267211.KI669560_gene1918	2.393e-237	749.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HKD3_k127_2599570_14	1122176.KB903542_gene389	5.117e-53	194.0	COG1437@1|root,COG1437@2|Bacteria,4NQQK@976|Bacteroidetes	976|Bacteroidetes	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
HKD3_k127_2599570_5	700598.Niako_5054	5.326e-200	629.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1IPZ7@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_261021_0	700598.Niako_2562	0.0	1096.0	COG1640@1|root,COG1640@2|Bacteria,4NF7Z@976|Bacteroidetes,1IPKN@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	CBM_20,Glyco_hydro_77
HKD3_k127_261021_1	925409.KI911562_gene2718	2.488e-249	774.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
HKD3_k127_261021_3	525903.Taci_1617	2.397e-55	200.0	COG0640@1|root,COG0640@2|Bacteria,3TAVK@508458|Synergistetes	508458|Synergistetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_261021_4	1270196.JCKI01000001_gene3461	1.86e-35	145.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,1IS00@117747|Sphingobacteriia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
HKD3_k127_261021_2	1358423.N180_15385	1.158e-96	343.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1IPJ8@117747|Sphingobacteriia	976|Bacteroidetes	DM	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
HKD3_k127_2631535_19	1348583.ATLH01000005_gene815	7.531e-08	53.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1HX0R@117743|Flavobacteriia,1F8VN@104264|Cellulophaga	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
HKD3_k127_2631535_12	1166018.FAES_1352	7.341e-66	235.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,47MQV@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD3_k127_2631535_9	925409.KI911562_gene1674	1.57e-77	265.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1IQV2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
HKD3_k127_2631535_7	700598.Niako_4568	2.452e-116	386.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1IP03@117747|Sphingobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD3_k127_2631535_10	525373.HMPREF0766_10010	1.766e-71	250.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1IRSV@117747|Sphingobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
HKD3_k127_2631535_5	743722.Sph21_3621	3.699e-192	610.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1IPIU@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
HKD3_k127_2631535_4	925409.KI911562_gene2716	3.032e-302	932.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1IP50@117747|Sphingobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HKD3_k127_2631535_11	925409.KI911562_gene679	3.33e-70	244.0	COG2207@1|root,COG2207@2|Bacteria,4NS41@976|Bacteroidetes,1J0BF@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_2631535_15	1123276.KB893311_gene3174	6.251e-38	149.0	COG2207@1|root,COG2207@2|Bacteria,4NS1A@976|Bacteroidetes,47QRZ@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_2631535_2	1121481.AUAS01000002_gene3343	0.0	1042.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,47MMN@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_2631535_17	1089547.KB913013_gene4440	4.262e-18	85.0	COG2608@1|root,COG2608@2|Bacteria,4NURN@976|Bacteroidetes,47RXV@768503|Cytophagia	976|Bacteroidetes	P	PFAM Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HKD3_k127_2631535_16	700598.Niako_4311	4.235e-24	108.0	COG0845@1|root,COG0845@2|Bacteria,4NT55@976|Bacteroidetes,1ITNN@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
HKD3_k127_2631535_3	1406840.Q763_14780	6.652e-320	995.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia,2NT1D@237|Flavobacterium	976|Bacteroidetes	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD3_k127_2631535_1	1267211.KI669560_gene1599	0.0	1047.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
HKD3_k127_2631535_18	643867.Ftrac_1189	6.15e-16	80.0	2DXSD@1|root,346A9@2|Bacteria,4P5K0@976|Bacteroidetes,47VQR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2631535_14	1270196.JCKI01000003_gene1889	1.199e-40	154.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
HKD3_k127_2631535_6	1267211.KI669560_gene1525	1.774e-136	440.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
HKD3_k127_2631535_0	1267211.KI669560_gene1526	0.0	1236.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1IQ4F@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD3_k127_2631535_8	1267211.KI669560_gene1527	1.351e-93	312.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1ISIA@117747|Sphingobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
HKD3_k127_2631535_13	1123248.KB893318_gene4209	5.67e-59	208.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_2635839_6	1123248.KB893317_gene4320	2.965e-76	263.0	COG0265@1|root,COG0265@2|Bacteria,4NGA4@976|Bacteroidetes,1IPPQ@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
HKD3_k127_2635839_4	688270.Celal_1019	2.071e-96	325.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia,1F892@104264|Cellulophaga	976|Bacteroidetes	IQ	acyl protein synthase acyl-CoA reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
HKD3_k127_2635839_10	468059.AUHA01000002_gene408	8.661e-10	69.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1IR8U@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2635839_2	1123248.KB893359_gene2106	4.802e-199	624.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD3_k127_2635839_1	700598.Niako_2173	1.884e-222	715.0	COG1629@1|root,COG3664@1|root,COG1629@2|Bacteria,COG3664@2|Bacteria,4P4MW@976|Bacteroidetes,1IP05@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_2635839_7	1267211.KI669560_gene747	5.91e-72	256.0	2DBS0@1|root,2ZANT@2|Bacteria,4NQP3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2635839_8	700598.Niako_0890	2.488e-55	199.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1ISGQ@117747|Sphingobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD3_k127_2635839_3	1123248.KB893318_gene4179	2.719e-138	445.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD3_k127_2635839_5	1122605.KB893645_gene1102	2.374e-80	275.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes	976|Bacteroidetes	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
HKD3_k127_2635839_0	1122605.KB893643_gene833	2.637e-236	738.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1IQ9E@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
HKD3_k127_2727772_2	1267211.KI669560_gene1063	3.464e-47	170.0	COG2186@1|root,COG2186@2|Bacteria,4NEUP@976|Bacteroidetes,1IPCW@117747|Sphingobacteriia	976|Bacteroidetes	K	GntR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HKD3_k127_2727772_0	1122605.KB893625_gene2261	0.0	1048.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQCN@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_2727772_1	1492737.FEM08_18140	8.255e-51	184.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HZNT@117743|Flavobacteriia,2P027@237|Flavobacterium	976|Bacteroidetes	G	PRINTS Glycosyl hydrolase family 29 signature	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
HKD3_k127_2738928_2	1454007.JAUG01000039_gene4260	9.023e-160	512.0	COG2755@1|root,COG2755@2|Bacteria,4NGSE@976|Bacteroidetes,1IPR1@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_2738928_0	1492737.FEM08_09580	9.762e-172	548.0	COG4289@1|root,COG4289@2|Bacteria,4NEU3@976|Bacteroidetes,1HZN1@117743|Flavobacteriia,2NVTK@237|Flavobacterium	976|Bacteroidetes	G	Uncharacterized protein conserved in bacteria (DUF2264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2264,Glyco_hydro_16
HKD3_k127_2738928_1	1454007.JAUG01000083_gene2262	2.275e-163	524.0	COG1331@1|root,COG1331@2|Bacteria,4PKHP@976|Bacteroidetes,1J0VB@117747|Sphingobacteriia	976|Bacteroidetes	O	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
HKD3_k127_2738928_3	1408813.AYMG01000002_gene3114	1.842e-08	56.0	COG1554@1|root,COG1554@2|Bacteria,4NHVP@976|Bacteroidetes,1IPI9@117747|Sphingobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_274184_3	700598.Niako_5120	1.69e-74	256.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1IP5W@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock protein Hsp90	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
HKD3_k127_274184_4	485918.Cpin_1724	1.124e-60	216.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_4
HKD3_k127_274184_0	925409.KI911562_gene1560	3.29e-243	767.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD3_k127_274184_1	1267211.KI669560_gene2472	3.879e-132	429.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_274184_5	485918.Cpin_6987	1.04e-46	180.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD3_k127_274184_2	700598.Niako_5113	3.606e-86	292.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD3_k127_2753257_2	1121904.ARBP01000018_gene2685	2.336e-13	74.0	2E74W@1|root,331P9@2|Bacteria,4P4VB@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_2753257_0	1121875.KB907547_gene2995	6.918e-77	268.0	COG2067@1|root,COG2067@2|Bacteria,4NX18@976|Bacteroidetes,1I5D9@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2753257_1	376686.Fjoh_3401	2.387e-35	142.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,1I22Y@117743|Flavobacteriia,2NVTZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_2753257_3	1202532.FF52_15702	8.923e-06	53.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_2773613_2	714943.Mucpa_3876	4.747e-54	195.0	COG2197@1|root,COG2197@2|Bacteria,4NJW3@976|Bacteroidetes,1IRVH@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_2773613_0	925409.KI911562_gene761	5.453e-188	591.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1INW2@117747|Sphingobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HKD3_k127_2773613_3	761193.Runsl_1795	3.182e-33	135.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
HKD3_k127_2773613_1	700598.Niako_5607	7.023e-162	526.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1ISDW@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
HKD3_k127_2773613_4	1304866.K413DRAFT_2325	1.593e-07	55.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia,36HMC@31979|Clostridiaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HKD3_k127_282850_0	1235803.C825_02948	2.863e-223	701.0	COG4225@1|root,COG4225@2|Bacteria,4NG6C@976|Bacteroidetes,2FNB0@200643|Bacteroidia,22WUT@171551|Porphyromonadaceae	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
HKD3_k127_282850_1	929713.NIASO_16075	1.208e-171	546.0	COG1874@1|root,COG1874@2|Bacteria,4P1ST@976|Bacteroidetes,1IWAV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
HKD3_k127_2874701_9	925409.KI911562_gene1435	1.853e-14	73.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1ISWJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
HKD3_k127_2874701_4	1122605.KB893626_gene2535	3.009e-97	332.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HKD3_k127_2874701_1	700598.Niako_5718	3.77e-159	511.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1IQ8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
HKD3_k127_2874701_8	700598.Niako_0572	5.31e-27	113.0	2DSW4@1|root,33HNK@2|Bacteria,4NW6Z@976|Bacteroidetes	976|Bacteroidetes	J	Ribosomal protein S23	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_2874701_7	700598.Niako_5717	1.564e-55	199.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1IS6G@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
HKD3_k127_2874701_0	925409.KI911562_gene951	4.797e-187	595.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1IPSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD3_k127_2874701_5	700598.Niako_6916	1.792e-91	311.0	COG1277@1|root,COG1277@2|Bacteria,4NICG@976|Bacteroidetes	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD3_k127_2874701_3	1267211.KI669560_gene2806	1.383e-109	362.0	COG1131@1|root,COG1131@2|Bacteria,4NPDD@976|Bacteroidetes,1J1AC@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_2874701_2	700598.Niako_6365	1.858e-139	472.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,1IPER@117747|Sphingobacteriia	976|Bacteroidetes	S	FUSC-like inner membrane protein yccS	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
HKD3_k127_2874701_6	398720.MED217_10969	2.498e-90	302.0	COG3662@1|root,COG3662@2|Bacteria,4NEYP@976|Bacteroidetes,1HWJP@117743|Flavobacteriia,2XK2Z@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
HKD3_k127_2885848_0	926556.Echvi_1504	1.226e-189	603.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,47N6N@768503|Cytophagia	976|Bacteroidetes	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
HKD3_k127_289429_0	1120965.AUBV01000003_gene494	1.079e-78	267.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,47NB9@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_2907159_0	1123248.KB893326_gene1293	0.0	1149.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_297265_3	1267211.KI669560_gene505	1.037e-189	599.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD3_k127_297265_5	1123057.P872_04760	1.073e-162	536.0	COG3291@1|root,COG5498@1|root,COG3291@2|Bacteria,COG5498@2|Bacteria,4PPR2@976|Bacteroidetes,47YQN@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_297265_0	1121889.AUDM01000005_gene1732	0.0	1466.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes,1HYBU@117743|Flavobacteriia,2NVRT@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_297265_4	1347342.BN863_18720	1.288e-185	588.0	COG5309@1|root,COG5309@2|Bacteria,4NFD7@976|Bacteroidetes,1HY34@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 17	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
HKD3_k127_297265_2	1450525.JATV01000002_gene1895	3.631e-241	752.0	COG2211@1|root,COG2211@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia,2NUNM@237|Flavobacterium	976|Bacteroidetes	G	MFS/sugar transport protein	uidB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
HKD3_k127_297265_1	1121897.AUGO01000002_gene2355	0.0	1127.0	COG5498@1|root,COG5498@2|Bacteria,4PI3C@976|Bacteroidetes,1I75X@117743|Flavobacteriia,2NY7K@237|Flavobacterium	976|Bacteroidetes	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_297265_6	313595.P700755_003177	3.703e-33	151.0	COG2273@1|root,COG2273@2|Bacteria,4PM7U@976|Bacteroidetes,1IJMV@117743|Flavobacteriia	976|Bacteroidetes	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_297265_8	926549.KI421517_gene28	1.386e-07	66.0	COG1520@1|root,COG2353@1|root,COG1520@2|Bacteria,COG2353@2|Bacteria,4PM20@976|Bacteroidetes,47X9N@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_297265_7	485917.Phep_2966	1.617e-09	61.0	COG3157@1|root,COG3157@2|Bacteria,4P4PF@976|Bacteroidetes,1IY8U@117747|Sphingobacteriia	976|Bacteroidetes	S	Type VI secretion system effector, Hcp	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_298766_1	760192.Halhy_1891	2.334e-115	374.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IVF5@117747|Sphingobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD3_k127_298766_2	1121272.KB903249_gene1573	4.912e-85	293.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4D96K@85008|Micromonosporales	201174|Actinobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4,GATase_6
HKD3_k127_298766_4	1122176.KB903542_gene400	6.733e-52	188.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1IT14@117747|Sphingobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_298766_0	700598.Niako_5773	8.18e-137	448.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IPDD@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
HKD3_k127_298766_3	1121481.AUAS01000003_gene3746	2.343e-65	230.0	COG1629@1|root,COG4771@2|Bacteria,4PKQZ@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_3069596_2	925409.KI911562_gene2112	3.022e-69	239.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1IP1V@117747|Sphingobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
HKD3_k127_3069596_1	471854.Dfer_5713	3.793e-72	252.0	COG0627@1|root,COG0627@2|Bacteria,4NE7D@976|Bacteroidetes,47KC0@768503|Cytophagia	976|Bacteroidetes	S	esterase	-	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
HKD3_k127_3069596_3	925409.KI911562_gene2809	3.515e-62	221.0	COG2849@1|root,COG2849@2|Bacteria,4NZNQ@976|Bacteroidetes	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD3_k127_3069596_0	1267211.KI669560_gene2060	2.396e-150	484.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IV0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
HKD3_k127_3147089_5	714943.Mucpa_1493	2.26e-84	290.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1IP44@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
HKD3_k127_3147089_10	649349.Lbys_2725	3.593e-66	231.0	COG2860@1|root,COG2860@2|Bacteria,4NEXS@976|Bacteroidetes,47KVV@768503|Cytophagia	976|Bacteroidetes	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
HKD3_k127_3147089_0	1267211.KI669560_gene2549	0.0	1125.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_3147089_12	700598.Niako_0289	8.606e-27	115.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1ITEJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_3147089_13	1123248.KB893316_gene4522	1.748e-26	113.0	2CG1Y@1|root,333IH@2|Bacteria,4NVMK@976|Bacteroidetes,1ISW4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_3147089_7	700598.Niako_2468	3.294e-81	279.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes	976|Bacteroidetes	E	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,Peptidase_S9
HKD3_k127_3147089_3	1267211.KI669560_gene2552	2.231e-219	684.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_3147089_2	700598.Niako_0184	3.426e-306	951.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IV4C@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_3147089_11	314285.KT71_06257	2.471e-35	145.0	28KF8@1|root,2ZA1G@2|Bacteria,1NZ2T@1224|Proteobacteria,1SQI9@1236|Gammaproteobacteria,1JAT9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3147089_6	1267211.KI669560_gene2651	2.777e-82	279.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD3_k127_3147089_8	1267211.KI669560_gene2652	9.517e-78	267.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1IP9T@117747|Sphingobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD3_k127_3147089_4	925409.KI911562_gene73	1.049e-88	296.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IST6@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HKD3_k127_3147089_9	1267211.KI669560_gene2393	1.145e-76	271.0	COG0683@1|root,COG0683@2|Bacteria,4PMPE@976|Bacteroidetes,1ISIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
HKD3_k127_3147089_1	1123248.KB893319_gene4078	2.184e-314	971.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD3_k127_3155055_2	1123057.P872_07975	2.735e-19	94.0	2ECP6@1|root,336KZ@2|Bacteria,4NVKQ@976|Bacteroidetes,47SB1@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4843)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4843
HKD3_k127_3155055_1	929562.Emtol_2643	6.318e-122	409.0	COG3193@1|root,COG3193@2|Bacteria,4NGRH@976|Bacteroidetes,47K1K@768503|Cytophagia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_3155055_0	1123057.P872_07965	8.142e-215	690.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47MXX@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_317776_1	1123248.KB893326_gene1526	7.143e-112	394.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1IPY8@117747|Sphingobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
HKD3_k127_317776_3	1123248.KB893326_gene1525	6.242e-38	147.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes,1IT2A@117747|Sphingobacteriia	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_317776_2	1123248.KB893326_gene1524	1.516e-44	168.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1ISTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
HKD3_k127_317776_0	1123248.KB893315_gene3210	0.0	1060.0	COG3408@1|root,COG3408@2|Bacteria,4PKJG@976|Bacteroidetes,1IQX7@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
HKD3_k127_3231763_5	1123248.KB893321_gene546	7.944e-133	433.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_3231763_8	485918.Cpin_1987	1.801e-57	209.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1IS0X@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
HKD3_k127_3231763_12	546267.NEIPOLOT_00550	4.279e-26	112.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,2KQT0@206351|Neisseriales	206351|Neisseriales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
HKD3_k127_3231763_11	925409.KI911562_gene2790	2.339e-27	120.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
HKD3_k127_3231763_7	246200.SPO3848	2.377e-87	295.0	COG3000@1|root,COG3000@2|Bacteria,1QSZU@1224|Proteobacteria,2VG1S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_3231763_0	925409.KI911562_gene2430	0.0	1191.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
HKD3_k127_3231763_10	925409.KI911562_gene1998	2.744e-39	152.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1IT35@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_3231763_3	1123248.KB893326_gene1473	5.949e-159	518.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1IV25@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_3231763_1	485918.Cpin_3681	4.244e-258	803.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_3231763_2	1123248.KB893317_gene4296	2.848e-226	718.0	COG1629@1|root,COG4771@2|Bacteria,4PMEH@976|Bacteroidetes,1J0ZJ@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
HKD3_k127_3231763_4	1123248.KB893326_gene1322	6.268e-159	513.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1IQE3@117747|Sphingobacteriia	976|Bacteroidetes	G	sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
HKD3_k127_3231763_9	1121373.KB903662_gene179	5.879e-42	157.0	COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,47RM9@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.7.2.1	ko:K00368,ko:K00405	ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020	M00156,M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_3231763_6	1267211.KI669560_gene1379	3.612e-119	394.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1IPXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_3237092_15	1267211.KI669560_gene806	1.335e-62	217.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1IQI6@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1233 Phytoene dehydrogenase and related	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_3237092_11	1267211.KI669560_gene805	2.314e-80	270.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,1IPYA@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_3237092_7	1267211.KI669560_gene804	8.596e-136	438.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,1IS5U@117747|Sphingobacteriia	976|Bacteroidetes	K	MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
HKD3_k127_3237092_16	1122605.KB893647_gene420	4.277e-61	226.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_3237092_4	273121.WS0025	3.707e-154	497.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_3237092_12	861299.J421_2491	2.544e-75	267.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	gne	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.1.3.26	ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
HKD3_k127_3237092_14	1049564.TevJSym_at00360	1.277e-63	233.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,1S0D6@1236|Gammaproteobacteria,1JAMS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	wbbO	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_4_2,Glycos_transf_1
HKD3_k127_3237092_1	1237149.C900_04206	9.655e-187	606.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_3237092_10	1279009.ADICEAN_00544	1.062e-104	351.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
HKD3_k127_3237092_17	509635.N824_13345	5.085e-45	177.0	COG3206@1|root,COG3206@2|Bacteria,4NH8F@976|Bacteroidetes,1INN0@117747|Sphingobacteriia	976|Bacteroidetes	M	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
HKD3_k127_3237092_8	909943.HIMB100_00023430	2.132e-127	428.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,4BQ84@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_3237092_2	925409.KI911562_gene279	6.516e-179	590.0	COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,1IPNG@117747|Sphingobacteriia	976|Bacteroidetes	M	export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
HKD3_k127_3237092_9	1313301.AUGC01000010_gene906	1.301e-106	355.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes	976|Bacteroidetes	E	Oxidoreductase NAD-binding domain protein	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_3237092_6	925409.KI911562_gene1125	1.4e-152	485.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IW1N@117747|Sphingobacteriia	976|Bacteroidetes	M	Nucleotidyl transferase	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD3_k127_3237092_13	491205.JARQ01000003_gene1973	7.725e-68	235.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia,3ZNQ9@59732|Chryseobacterium	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
HKD3_k127_3237092_0	925409.KI911562_gene1123	2.314e-188	592.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_3237092_3	925409.KI911562_gene1122	7.673e-178	585.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1IQFR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD3_k127_3237092_19	1121912.AUHD01000003_gene3023	3.123e-20	103.0	COG3187@1|root,COG3187@2|Bacteria,4PKCG@976|Bacteroidetes	976|Bacteroidetes	O	Domain of unknown function (DUF4377)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4377,META
HKD3_k127_3237092_23	1282360.ABAC460_03895	0.0004365	52.0	COG3187@1|root,COG3187@2|Bacteria,1NGG1@1224|Proteobacteria,2UJJM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	META domain	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META,YscW
HKD3_k127_3237092_5	700598.Niako_6728	1.176e-152	489.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1IPD6@117747|Sphingobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_3237092_18	700598.Niako_6727	1.14e-31	131.0	COG1514@1|root,COG1514@2|Bacteria,4NX5U@976|Bacteroidetes,1IYZ5@117747|Sphingobacteriia	976|Bacteroidetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_3237092_20	1123248.KB893348_gene112	3.113e-10	69.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_3237092_22	1121918.ARWE01000001_gene3392	4.781e-05	50.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,42T6V@68525|delta/epsilon subdivisions,2WPNI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
HKD3_k127_3237092_21	925409.KI911562_gene1113	5.834e-07	52.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1IP8N@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
HKD3_k127_3244604_4	925409.KI911562_gene1395	5.094e-65	224.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_3244604_2	700598.Niako_6695	7.998e-96	323.0	28K2C@1|root,2Z9RQ@2|Bacteria,4NJP3@976|Bacteroidetes,1ITQ3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3244604_0	700598.Niako_6694	7.05e-207	656.0	COG0671@1|root,COG0671@2|Bacteria,4NGYP@976|Bacteroidetes,1IR1B@117747|Sphingobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_3244604_1	700598.Niako_6693	2.231e-188	603.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1IP8I@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
HKD3_k127_3244604_3	1384054.N790_07260	5.312e-75	263.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,1T1US@1236|Gammaproteobacteria,1XDDZ@135614|Xanthomonadales	135614|Xanthomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD3_k127_3244604_5	493475.GARC_0679	2.232e-25	114.0	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,1RQ5T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_3244604_6	925409.KI911562_gene1007	6.82e-20	94.0	COG0346@1|root,COG0346@2|Bacteria,4NN5T@976|Bacteroidetes,1ISA8@117747|Sphingobacteriia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_3250561_3	1121859.KB890739_gene2362	9.888e-68	236.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,47N3E@768503|Cytophagia	976|Bacteroidetes	G	Beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_3250561_2	938709.AUSH02000045_gene482	8.168e-279	865.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD3_k127_3250561_1	929556.Solca_2759	2e-323	1012.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQ80@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
HKD3_k127_3250561_4	945713.IALB_2863	1.452e-33	145.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,FTP,He_PIG,PA,Peptidase_M30,Peptidase_M36,Peptidase_M6
HKD3_k127_3250561_0	761193.Runsl_1858	0.0	1039.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,47KZ5@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycosyl Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_328137_0	700598.Niako_3766	8.014e-138	452.0	COG1621@1|root,COG1621@2|Bacteria,4PKIG@976|Bacteroidetes,1ITPK@117747|Sphingobacteriia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
HKD3_k127_328137_1	925409.KI911562_gene28	2.659e-125	413.0	COG2755@1|root,COG2755@2|Bacteria,4NEAZ@976|Bacteroidetes	976|Bacteroidetes	E	COG NOG09493 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_2,Lipase_GDSL_3
HKD3_k127_328137_2	886293.Sinac_0921	1.54e-55	205.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR,BNR_2,CBM_2,RicinB_lectin_2
HKD3_k127_3299766_0	700598.Niako_5158	0.0	1373.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,1IVK4@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HKD3_k127_3299766_1	700598.Niako_5159	1.993e-90	302.0	COG2080@1|root,COG2080@2|Bacteria,4NPTH@976|Bacteroidetes,1IXDG@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD3_k127_3299766_2	700598.Niako_5160	5.21e-58	203.0	COG1319@1|root,COG1319@2|Bacteria,4NFT8@976|Bacteroidetes,1IV94@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
HKD3_k127_3316448_11	700598.Niako_7059	2.873e-93	316.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes	976|Bacteroidetes	P	Phosphate ABC transporter substrate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD3_k127_3316448_17	925409.KI911562_gene218	2.059e-48	179.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1IYAU@117747|Sphingobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD3_k127_3316448_1	925409.KI911562_gene219	6.906e-219	686.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1IW4I@117747|Sphingobacteriia	976|Bacteroidetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HKD3_k127_3316448_15	925409.KI911562_gene1784	1.221e-60	222.0	COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,1IXG8@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_3316448_3	485918.Cpin_1205	2.628e-179	569.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IVK0@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the thiolase family	-	-	2.3.1.174,2.3.1.9	ko:K00626,ko:K07823	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_3316448_4	700598.Niako_7047	3.362e-179	565.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1IQMY@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_3316448_16	700598.Niako_1561	3.534e-51	195.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,1IYEN@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_3316448_18	760192.Halhy_5034	5.73e-25	108.0	2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_3316448_7	1267211.KI669560_gene266	1.604e-117	397.0	COG1807@1|root,COG1807@2|Bacteria,4NKI5@976|Bacteroidetes,1J09F@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_3316448_8	700598.Niako_5494	8.839e-115	380.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_3316448_0	700598.Niako_4480	4.051e-306	989.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_3316448_6	700598.Niako_5484	3.447e-136	445.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
HKD3_k127_3316448_10	700598.Niako_5483	2.826e-108	355.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1IPT2@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
HKD3_k127_3316448_5	700598.Niako_5482	2.48e-142	467.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
HKD3_k127_3316448_12	700598.Niako_5507	1.055e-80	281.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1IP5H@117747|Sphingobacteriia	976|Bacteroidetes	NU	COG1705 Muramidase (flagellum-specific)	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
HKD3_k127_3316448_14	700598.Niako_5506	4.559e-70	241.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1ISTD@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HKD3_k127_3316448_9	700598.Niako_5505	1.872e-113	388.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
HKD3_k127_3316448_2	1267211.KI669560_gene1356	3.677e-199	625.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD3_k127_3316448_13	1267211.KI669560_gene1355	4.171e-73	253.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1ISPN@117747|Sphingobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HKD3_k127_3316448_19	761193.Runsl_2278	1.908e-20	94.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,47JMU@768503|Cytophagia	976|Bacteroidetes	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_3437621_0	925409.KI911562_gene274	6.577e-253	793.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1IPWE@117747|Sphingobacteriia	976|Bacteroidetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
HKD3_k127_3437621_3	485918.Cpin_3971	9.711e-166	533.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1IR44@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HKD3_k127_3437621_2	1122621.ATZA01000008_gene921	3.787e-170	547.0	2BVKK@1|root,2Z8PC@2|Bacteria,4NF9X@976|Bacteroidetes,1ISAS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3437621_1	1267211.KI669560_gene722	2.517e-192	604.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD3_k127_3437621_4	485918.Cpin_1032	1.61e-58	209.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,1ISNQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD3_k127_3437621_5	1267211.KI669560_gene720	6.949e-05	48.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD3_k127_3468995_0	1123248.KB893386_gene1917	0.0	1130.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IR88@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD3_k127_3468995_2	1279009.ADICEAN_02492	1.341e-178	567.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,47NZB@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HKD3_k127_3468995_1	1121481.AUAS01000012_gene366	5.73e-322	998.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,47KUW@768503|Cytophagia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
HKD3_k127_3475943_2	1121904.ARBP01000018_gene2707	5.978e-51	182.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,47YNU@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
HKD3_k127_3475943_4	1121875.KB907556_gene612	3.845e-39	152.0	2E5SP@1|root,330H2@2|Bacteria,4P4B3@976|Bacteroidetes	976|Bacteroidetes	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
HKD3_k127_3475943_0	1123242.JH636434_gene5275	1.366e-142	467.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
HKD3_k127_3475943_1	1239962.C943_00981	3.802e-130	421.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3643694_3	1122605.KB893637_gene3292	2.494e-49	183.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IP2E@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HKD3_k127_3643694_0	1123248.KB893321_gene470	3.012e-151	490.0	COG1566@1|root,COG1566@2|Bacteria,4PMCY@976|Bacteroidetes,1J0U2@117747|Sphingobacteriia	976|Bacteroidetes	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
HKD3_k127_3643694_1	700598.Niako_5810	4.878e-60	214.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,1IRUG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
HKD3_k127_3643694_2	1267211.KI669560_gene292	1.263e-53	195.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_3643694_4	1267211.KI669560_gene293	5.027e-34	139.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_364850_0	1267211.KI669560_gene78	8.888e-192	603.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1IQUC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_364850_1	925409.KI911562_gene428	8.122e-143	460.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1IPHE@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_364850_3	1123226.KB899313_gene1817	1.166e-14	78.0	COG0662@1|root,COG0662@2|Bacteria,1V9DQ@1239|Firmicutes,4HJK4@91061|Bacilli,26YM0@186822|Paenibacillaceae	91061|Bacilli	G	Cupin domain	algA	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_364850_2	925409.KI911562_gene429	9.478e-92	303.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD3_k127_3650303_1	1123248.KB893385_gene4872	3.605e-137	451.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
HKD3_k127_3650303_0	925409.KI911562_gene1619	1.212e-269	839.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HKD3_k127_3656058_1	925409.KI911562_gene625	1.648e-115	375.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1IQPD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD3_k127_3656058_3	1123248.KB893331_gene3773	1.553e-93	317.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1IS1R@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
HKD3_k127_3656058_2	1267211.KI669560_gene385	6.921e-105	351.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1IS2B@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_3656058_7	1122605.KB893628_gene4438	1.355e-26	123.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IPS5@117747|Sphingobacteriia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_3656058_4	1123248.KB893331_gene3771	9.685e-79	276.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IPS5@117747|Sphingobacteriia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD3_k127_3656058_0	700598.Niako_6067	6.857e-248	774.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1INZ2@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
HKD3_k127_3656058_5	926556.Echvi_3204	3.962e-47	175.0	COG4319@1|root,COG4319@2|Bacteria,4PKP4@976|Bacteroidetes,47YGA@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_3656058_6	700598.Niako_0935	1.486e-46	175.0	COG3631@1|root,COG3631@2|Bacteria,4P470@976|Bacteroidetes	976|Bacteroidetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3664829_3	1358423.N180_04590	8.357e-67	235.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IWD6@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_3664829_2	925409.KI911562_gene2330	1.133e-80	275.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
HKD3_k127_3664829_1	925409.KI911562_gene2033	1.506e-192	609.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1IQ2Y@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
HKD3_k127_3664829_4	925409.KI911562_gene2031	1.99e-64	227.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_3664829_0	700598.Niako_0423	6.064e-286	887.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IPEF@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HKD3_k127_3664829_5	700598.Niako_2270	9.679e-35	141.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1IY8D@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD3_k127_3664829_6	553217.ENHAE0001_1256	6.171e-19	88.0	COG0500@1|root,COG0500@2|Bacteria,1NAKF@1224|Proteobacteria,1T3M3@1236|Gammaproteobacteria,3NQBA@468|Moraxellaceae	1236|Gammaproteobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
HKD3_k127_3674483_0	925409.KI911562_gene392	1.842e-316	998.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1IP6G@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_3674483_2	929713.NIASO_18385	9.731e-38	146.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,1ITH9@117747|Sphingobacteriia	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
HKD3_k127_3674483_3	929713.NIASO_18380	2.811e-33	136.0	COG5642@1|root,COG5642@2|Bacteria,4NX1V@976|Bacteroidetes,1IUEV@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
HKD3_k127_3674483_1	700598.Niako_4356	4.936e-121	402.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_3677819_2	1122605.KB893628_gene4395	8.596e-201	634.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,1INWR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Bacterial alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
HKD3_k127_3677819_3	1454007.JAUG01000042_gene75	2.394e-181	572.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,1IT8C@117747|Sphingobacteriia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
HKD3_k127_3677819_0	1122605.KB893637_gene3425	0.0	1154.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,4NEM0@976|Bacteroidetes,1IQ2J@117747|Sphingobacteriia	976|Bacteroidetes	IQ	rhamnulose-1-phosphate aldolase alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
HKD3_k127_3677819_5	926549.KI421517_gene1658	3.689e-43	160.0	COG3254@1|root,COG3254@2|Bacteria,4NSEM@976|Bacteroidetes,47R8A@768503|Cytophagia	976|Bacteroidetes	G	Involved in the anomeric conversion of L-rhamnose	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
HKD3_k127_3677819_1	926549.KI421517_gene1657	9.251e-216	675.0	COG4952@1|root,COG4952@2|Bacteria,4NFWW@976|Bacteroidetes,47KMM@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype	-	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	-
HKD3_k127_3677819_4	509635.N824_04800	4.449e-170	545.0	COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes,1IPDX@117747|Sphingobacteriia	976|Bacteroidetes	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
HKD3_k127_3683482_16	700598.Niako_4252	4.312e-28	121.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1IT9I@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_3683482_17	1089547.KB913013_gene1290	4.689e-25	107.0	2ADIU@1|root,31396@2|Bacteria,4NW8B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3683482_14	313603.FB2170_15398	1.885e-39	161.0	COG0454@1|root,COG0456@2|Bacteria,4NKGU@976|Bacteroidetes,1HZFA@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_3683482_5	1185876.BN8_00852	3.137e-91	317.0	COG0793@1|root,COG0793@2|Bacteria,4NEFX@976|Bacteroidetes,47S2P@768503|Cytophagia	976|Bacteroidetes	M	Peptidase, S41 family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
HKD3_k127_3683482_18	523791.Kkor_2458	7.726e-23	109.0	COG1246@1|root,COG1246@2|Bacteria,1NBIV@1224|Proteobacteria,1SD3W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_3683482_13	1123234.AUKI01000011_gene1298	8.403e-52	194.0	COG0346@1|root,COG0346@2|Bacteria,4NRR0@976|Bacteroidetes	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_3683482_9	1123234.AUKI01000011_gene1297	8.006e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,4NM7R@976|Bacteroidetes,1I1GD@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_3683482_8	468059.AUHA01000002_gene946	5.46e-57	210.0	COG2267@1|root,COG2267@2|Bacteria,4NNPI@976|Bacteroidetes	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD3_k127_3683482_7	452637.Oter_1075	5.377e-61	218.0	arCOG09454@1|root,30G4A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3683482_3	1123248.KB893385_gene4895	3.707e-110	362.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1ISF2@117747|Sphingobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_3683482_4	1123248.KB893385_gene4894	5.939e-98	331.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,1IXUS@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_3683482_6	1123248.KB893385_gene4893	7.616e-82	286.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_3683482_1	700598.Niako_6570	1.024e-208	652.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1INVN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
HKD3_k127_3683482_11	1189612.A33Q_2629	3.781e-53	194.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD3_k127_3683482_0	1122605.KB893643_gene502	7.516e-232	730.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1ISE6@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HKD3_k127_3683482_12	700598.Niako_6574	1.74e-52	191.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1IT6C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_3683482_2	1500281.JQKZ01000011_gene1989	7.157e-187	593.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,1HWJT@117743|Flavobacteriia,3ZNTM@59732|Chryseobacterium	976|Bacteroidetes	C	4-hydroxybutyrate CoA-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD3_k127_3683482_15	760192.Halhy_0595	1.143e-33	136.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	5.3.1.16	ko:K01814,ko:K03825	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HKD3_k127_3683482_10	1122605.KB893628_gene4403	1.075e-56	204.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1IZCY@117747|Sphingobacteriia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
HKD3_k127_3737157_4	485918.Cpin_3083	4.123e-94	317.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1INQT@117747|Sphingobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
HKD3_k127_3737157_1	1123248.KB893314_gene3282	4.086e-138	447.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IPZG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD3_k127_3737157_0	1123248.KB893329_gene4475	1.941e-199	634.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_3737157_3	700598.Niako_0315	5.434e-118	390.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1IQ3K@117747|Sphingobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
HKD3_k127_3737157_6	925409.KI911562_gene1921	5.892e-67	228.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1J0P2@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
HKD3_k127_3737157_2	700598.Niako_0318	2.589e-136	443.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1INQY@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD3_k127_3737157_5	1123248.KB893385_gene4812	5.524e-76	263.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1ISPM@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
HKD3_k127_3737157_7	1123248.KB893385_gene4813	2.044e-36	140.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_3741842_8	929703.KE386491_gene1945	1.211e-42	160.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD3_k127_3741842_5	929713.NIASO_13605	7.585e-65	226.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,1ITCU@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_3741842_13	1185876.BN8_00682	5.354e-06	55.0	COG3678@1|root,COG3678@2|Bacteria,4NWN1@976|Bacteroidetes	976|Bacteroidetes	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
HKD3_k127_3741842_2	1168034.FH5T_02515	1.359e-127	416.0	COG3934@1|root,COG3934@2|Bacteria,4NGQC@976|Bacteroidetes,2FR92@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
HKD3_k127_3741842_11	1267211.KI669560_gene2522	2.343e-26	113.0	COG2010@1|root,COG2010@2|Bacteria,4NTWV@976|Bacteroidetes,1J09D@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	aniA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_3741842_0	1123276.KB893253_gene3390	0.0	1180.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KPV@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD3_k127_3741842_4	760192.Halhy_0717	3.972e-75	254.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1IWSE@117747|Sphingobacteriia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD3_k127_3741842_6	1122621.ATZA01000035_gene3612	3.211e-58	210.0	COG1917@1|root,COG1917@2|Bacteria,4NR0K@976|Bacteroidetes,1IT3Z@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_3741842_1	760192.Halhy_0714	6.836e-146	467.0	COG2207@1|root,COG2207@2|Bacteria,4NDYY@976|Bacteroidetes,1IQRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_3741842_3	1122605.KB893637_gene3154	7.254e-100	338.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1IXHP@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
HKD3_k127_3741842_10	886379.AEWI01000065_gene2306	1.985e-41	154.0	COG3549@1|root,COG3549@2|Bacteria,4NSZ2@976|Bacteroidetes,2FY7C@200643|Bacteroidia	976|Bacteroidetes	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
HKD3_k127_3741842_7	1267211.KI669560_gene2657	1.375e-44	163.0	COG3093@1|root,COG3093@2|Bacteria,4NSBZ@976|Bacteroidetes,1ITK1@117747|Sphingobacteriia	976|Bacteroidetes	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
HKD3_k127_3741842_9	313628.LNTAR_01342	1.483e-42	160.0	29EWK@1|root,301UB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3749669_9	1313301.AUGC01000005_gene280	2.326e-16	87.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_3749669_2	1122621.ATZA01000045_gene3551	6.057e-134	436.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1IQPQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HKD3_k127_3749669_3	1267211.KI669560_gene2213	2.812e-106	351.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1INMM@117747|Sphingobacteriia	976|Bacteroidetes	S	iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
HKD3_k127_3749669_0	925409.KI911562_gene2709	3.029e-183	582.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IWFS@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_3749669_4	1123248.KB893323_gene1562	2.824e-104	353.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,1IRY1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD3_k127_3749669_7	485918.Cpin_4004	1.347e-60	213.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,1IT52@117747|Sphingobacteriia	976|Bacteroidetes	FJ	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD3_k127_3749669_5	1267211.KI669560_gene1511	1.16e-89	306.0	28N01@1|root,2ZB6M@2|Bacteria,4NFN1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3749669_8	1267211.KI669560_gene1510	1.979e-44	166.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1ISS3@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
HKD3_k127_3749669_1	1270196.JCKI01000008_gene1632	5.58e-135	441.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1INWC@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD3_k127_3749669_6	1296416.JACB01000017_gene5141	4.615e-65	231.0	COG0500@1|root,COG2226@2|Bacteria,4PH0U@976|Bacteroidetes,1IHRF@117743|Flavobacteriia,2YIT4@290174|Aquimarina	976|Bacteroidetes	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD3_k127_3767483_1	472759.Nhal_2488	3.32e-29	130.0	COG4932@1|root,COG4932@2|Bacteria,1P8KK@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3767483_0	1227739.Hsw_PA0143	6.557e-84	292.0	COG1596@1|root,COG2204@1|root,COG1596@2|Bacteria,COG2204@2|Bacteria,4NPAE@976|Bacteroidetes,47QS5@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
HKD3_k127_3767483_2	491205.JARQ01000007_gene3217	4.223e-27	112.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
HKD3_k127_3771688_17	1081640.AGFU01000005_gene1066	1.235e-60	218.0	COG3867@1|root,COG3867@2|Bacteria,1R33X@1224|Proteobacteria,2U17E@28211|Alphaproteobacteria,2K1Q3@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
HKD3_k127_3771688_3	1122621.ATZA01000009_gene323	5.259e-255	803.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPJF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_3771688_14	700598.Niako_1887	9.321e-95	321.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1IRW5@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HKD3_k127_3771688_12	714943.Mucpa_0786	1.731e-103	342.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1IQ62@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD3_k127_3771688_10	700598.Niako_1885	9.831e-107	351.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1IPKD@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD3_k127_3771688_13	925409.KI911562_gene1455	1.243e-97	329.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1IPT7@117747|Sphingobacteriia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
HKD3_k127_3771688_20	1121904.ARBP01000102_gene3448	4.923e-14	83.0	COG4099@1|root,COG4932@1|root,COG4099@2|Bacteria,COG4932@2|Bacteria,4NFU4@976|Bacteroidetes,47KEJ@768503|Cytophagia	976|Bacteroidetes	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin
HKD3_k127_3771688_2	1123248.KB893323_gene1642	6.834e-267	831.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1IQTE@117747|Sphingobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
HKD3_k127_3771688_16	1123248.KB893323_gene1643	2.326e-71	244.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes	976|Bacteroidetes	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HKD3_k127_3771688_4	700598.Niako_2068	1.561e-239	766.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	2|Bacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
HKD3_k127_3771688_11	925409.KI911562_gene2016	4.095e-104	344.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1IP6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD3_k127_3771688_8	1123248.KB893329_gene4439	1.797e-129	421.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1INVP@117747|Sphingobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_3771688_18	1123248.KB893318_gene4142	4.339e-40	157.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1ISRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_3771688_0	925409.KI911562_gene2165	0.0	1292.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD3_k127_3771688_6	929556.Solca_2062	3.165e-169	561.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1IPNA@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	aefA	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
HKD3_k127_3771688_7	1123248.KB893359_gene2053	8.304e-164	520.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD3_k127_3771688_1	1123248.KB893359_gene2052	5.953e-273	865.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
HKD3_k127_3771688_9	925409.KI911562_gene2260	3.344e-107	357.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD3_k127_3774235_11	700598.Niako_0308	5.727e-96	315.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD3_k127_3774235_14	1267211.KI669560_gene1283	2.576e-57	204.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD3_k127_3774235_19	700598.Niako_5467	1.638e-38	148.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1ITHS@117747|Sphingobacteriia	976|Bacteroidetes	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_3774235_5	600809.BPLAN_123	4.679e-186	591.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,3IVEG@39782|Blattabacteriaceae	976|Bacteroidetes	I	Acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_3774235_15	1123277.KB893173_gene1781	2.13e-55	203.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,47NYB@768503|Cytophagia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD3_k127_3774235_20	485918.Cpin_1208	2.128e-19	93.0	2AVDM@1|root,31M58@2|Bacteria,4NUN6@976|Bacteroidetes,1IUDD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
HKD3_k127_3774235_2	700598.Niako_7358	3.986e-227	709.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1IPUW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD3_k127_3774235_16	700598.Niako_5643	1.258e-53	194.0	COG0454@1|root,COG0456@2|Bacteria,4NWTW@976|Bacteroidetes,1IZJT@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD3_k127_3774235_12	945713.IALB_2233	5.922e-90	314.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
HKD3_k127_3774235_13	153721.MYP_4621	1.48e-77	267.0	COG0491@1|root,COG0491@2|Bacteria,4NQCT@976|Bacteroidetes,47QDG@768503|Cytophagia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_3774235_21	1121887.AUDK01000002_gene2123	1.501e-15	79.0	COG2217@1|root,COG2217@2|Bacteria,4NYQS@976|Bacteroidetes,1IKQ0@117743|Flavobacteriia,2NXMJ@237|Flavobacterium	976|Bacteroidetes	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3774235_0	925409.KI911562_gene1462	0.0	1798.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IRF8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC
HKD3_k127_3774235_7	700598.Niako_5698	1.368e-117	388.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,1ITSA@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_3774235_9	1123248.KB893315_gene3189	3.694e-114	372.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,1ISXM@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD3_k127_3774235_6	929556.Solca_2839	1.989e-143	467.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_3774235_17	700598.Niako_1261	3.712e-50	183.0	COG0680@1|root,COG0680@2|Bacteria,4NRQY@976|Bacteroidetes,1IT7D@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0680 Ni Fe-hydrogenase maturation factor	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
HKD3_k127_3774235_8	700598.Niako_1262	1.897e-115	376.0	COG1969@1|root,COG1969@2|Bacteria,4NIDY@976|Bacteroidetes,1IP16@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1969 Ni Fe-hydrogenase I cytochrome b subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
HKD3_k127_3774235_1	714943.Mucpa_5245	0.0	1004.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1IPFW@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0374 Ni Fe-hydrogenase I large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
HKD3_k127_3774235_4	700598.Niako_1264	1.322e-200	631.0	COG1740@1|root,COG1740@2|Bacteria,4NK1F@976|Bacteroidetes,1IRKT@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1740 Ni Fe-hydrogenase I small subunit	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
HKD3_k127_3774235_10	714943.Mucpa_5248	6.883e-99	332.0	COG0378@1|root,COG0378@2|Bacteria,4NJ0P@976|Bacteroidetes,1IR6X@117747|Sphingobacteriia	976|Bacteroidetes	KO	COGs COG0378 Ni2 -binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
HKD3_k127_3774235_3	700598.Niako_1268	4.249e-219	702.0	COG0068@1|root,COG0068@2|Bacteria,4NIZ1@976|Bacteroidetes,1IRM2@117747|Sphingobacteriia	976|Bacteroidetes	O	TIGRFAM NiFe hydrogenase maturation protein HypF	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
HKD3_k127_3777847_1	471854.Dfer_2837	2.186e-97	329.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MGC@768503|Cytophagia	976|Bacteroidetes	K	PFAM Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4
HKD3_k127_3777847_0	1235803.C825_03498	5.57e-205	659.0	COG1874@1|root,COG1874@2|Bacteria,4NINF@976|Bacteroidetes,2FMTN@200643|Bacteroidia,22ZWQ@171551|Porphyromonadaceae	976|Bacteroidetes	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
HKD3_k127_3777847_3	1121904.ARBP01000025_gene6117	1.635e-26	125.0	2DBBA@1|root,2Z86Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3788035_1	700598.Niako_0884	5.412e-124	415.0	COG1119@1|root,COG1119@2|Bacteria,4NEWY@976|Bacteroidetes,1INTA@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
HKD3_k127_3788035_0	1123248.KB893370_gene4998	4.574e-202	638.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1IPRF@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_3788035_2	471854.Dfer_2652	6.651e-54	193.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,47QVM@768503|Cytophagia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
HKD3_k127_3809281_0	1122605.KB893646_gene202	8.283e-305	944.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD3_k127_3809281_1	1122605.KB893639_gene3042	3.462e-156	509.0	COG4244@1|root,COG4244@2|Bacteria,4PN2J@976|Bacteroidetes,1J0ZC@117747|Sphingobacteriia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,PSCyt1
HKD3_k127_3823572_7	1122605.KB893646_gene145	5.157e-27	115.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_9
HKD3_k127_3823572_3	1267211.KI669560_gene702	4.256e-93	322.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1INNS@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HKD3_k127_3823572_5	1123248.KB893319_gene4068	8.102e-59	214.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3823572_1	700598.Niako_5763	2.958e-114	372.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1IQ9A@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
HKD3_k127_3823572_0	929713.NIASO_02330	1.301e-123	420.0	COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1IQZ9@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3823572_6	1122605.KB893646_gene140	9.489e-39	150.0	COG2105@1|root,COG2105@2|Bacteria,4NUSS@976|Bacteroidetes,1IZG0@117747|Sphingobacteriia	976|Bacteroidetes	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
HKD3_k127_3823572_4	925409.KI911562_gene885	2.997e-61	217.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1IRJ2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
HKD3_k127_3823572_2	700598.Niako_5766	2.843e-109	359.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IQ2Z@117747|Sphingobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD3_k127_382640_2	1122605.KB893626_gene2806	4.828e-40	149.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD3_k127_382640_0	925409.KI911562_gene485	2.004e-111	368.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1IQ92@117747|Sphingobacteriia	976|Bacteroidetes	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HKD3_k127_382640_3	1380370.JIBA01000017_gene2927	1.606e-38	155.0	COG0702@1|root,COG0702@2|Bacteria,2ICEY@201174|Actinobacteria,4FHR4@85021|Intrasporangiaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
HKD3_k127_382640_1	143224.JQMD01000002_gene3643	4.877e-44	169.0	COG1929@1|root,COG1929@2|Bacteria,4NFK8@976|Bacteroidetes,1HXJ7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
HKD3_k127_3834_0	929703.KE386491_gene639	2.483e-275	880.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y3K@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_3834_1	1270196.JCKI01000004_gene1117	1.738e-134	446.0	COG3637@1|root,COG3637@2|Bacteria,4PM31@976|Bacteroidetes	976|Bacteroidetes	M	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
HKD3_k127_3834_2	700598.Niako_6033	5.442e-17	80.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HKD3_k127_3874948_3	471854.Dfer_1860	5.039e-16	77.0	COG4948@1|root,COG4948@2|Bacteria,4NGZF@976|Bacteroidetes,47NF7@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_3874948_0	509635.N824_10105	9.127e-272	844.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IQDG@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD3_k127_3874948_2	391596.PBAL39_10776	8.666e-52	186.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,1ISZ2@117747|Sphingobacteriia	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
HKD3_k127_3874948_1	1122931.AUAE01000009_gene4933	2.539e-125	409.0	COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,2FQ6F@200643|Bacteroidia,231S2@171551|Porphyromonadaceae	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
HKD3_k127_3981018_2	700598.Niako_5077	1.091e-105	349.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD3_k127_3981018_3	945713.IALB_2990	7.47e-60	215.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4397
HKD3_k127_3981018_1	925409.KI911562_gene1530	1.773e-127	419.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1IRGQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_3981018_0	1267211.KI669560_gene1216	2.939e-199	627.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
HKD3_k127_3983028_1	925409.KI911562_gene1384	2.681e-115	374.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1IQ4Y@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_3983028_0	485917.Phep_2883	2.928e-228	714.0	COG0673@1|root,COG0673@2|Bacteria,4NH13@976|Bacteroidetes,1IWEU@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_3983028_2	760192.Halhy_1025	4.004e-55	205.0	COG1073@1|root,COG1073@2|Bacteria,4PP14@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD3_k127_3983028_3	1227739.Hsw_2715	4.37e-55	202.0	COG0386@1|root,COG0386@2|Bacteria,4NP8C@976|Bacteroidetes,47Q5J@768503|Cytophagia	976|Bacteroidetes	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD3_k127_3983028_4	1048983.EL17_01155	6.924e-21	93.0	COG2220@1|root,COG2220@2|Bacteria,4NI69@976|Bacteroidetes,47K8S@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HKD3_k127_4005999_12	1249997.JHZW01000003_gene3609	5.247e-33	130.0	COG2963@1|root,COG2963@2|Bacteria,4NSB9@976|Bacteroidetes,1I3XZ@117743|Flavobacteriia,2PIPI@252356|Maribacter	976|Bacteroidetes	L	Protein of unknown function (DUF2805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2805
HKD3_k127_4005999_5	1356852.N008_17300	6.693e-142	460.0	COG0415@1|root,COG0415@2|Bacteria,4NFZG@976|Bacteroidetes,47KH9@768503|Cytophagia	976|Bacteroidetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	FAD_binding_7
HKD3_k127_4005999_4	468059.AUHA01000004_gene2343	3.142e-142	465.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1IP4Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_4005999_10	1267211.KI669560_gene2468	3.754e-84	282.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_4005999_9	925409.KI911562_gene2780	5.422e-86	287.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4005999_0	700598.Niako_0350	0.0	1055.0	COG4206@1|root,COG4206@2|Bacteria,4PKY5@976|Bacteroidetes,1IQUU@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
HKD3_k127_4005999_2	760192.Halhy_1263	1.212e-197	636.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_4005999_11	929556.Solca_0459	7.913e-36	140.0	COG0662@1|root,COG0662@2|Bacteria,4NTZN@976|Bacteroidetes,1IYU4@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_4005999_8	1267211.KI669560_gene1666	4.069e-102	352.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes	976|Bacteroidetes	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
HKD3_k127_4005999_1	700598.Niako_2221	1.378e-210	661.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IRC7@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
HKD3_k127_4005999_7	643867.Ftrac_1117	5.183e-108	356.0	COG0189@1|root,COG0189@2|Bacteria,4NFXS@976|Bacteroidetes,47U3S@768503|Cytophagia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4005999_3	153721.MYP_4380	2.11e-167	532.0	COG2141@1|root,COG2141@2|Bacteria,4NHGI@976|Bacteroidetes,47MJ4@768503|Cytophagia	976|Bacteroidetes	C	Luciferase-like monooxygenase	yhbW	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_4005999_6	247490.KSU1_D1001	1.204e-132	439.0	COG1538@1|root,COG1538@2|Bacteria,2IX0B@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane lipoprotein IbeB	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_4005999_13	247490.KSU1_D1002	1.025e-11	65.0	COG0841@1|root,COG0841@2|Bacteria,2IX2G@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD3_k127_4080305_0	485918.Cpin_2323	2.857e-269	840.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1IPCR@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD3_k127_4080305_3	925409.KI911562_gene2239	9.526e-181	569.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HKD3_k127_4080305_1	925409.KI911562_gene2238	1.105e-253	789.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HKD3_k127_4080305_6	1124780.ANNU01000016_gene1860	7.61e-25	112.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,47RXN@768503|Cytophagia	976|Bacteroidetes	J	2'-5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_4080305_2	485918.Cpin_1945	1.142e-234	743.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD3_k127_4080305_5	1267211.KI669560_gene1972	4.804e-51	184.0	COG4430@1|root,COG4430@2|Bacteria,4NQAJ@976|Bacteroidetes,1IUMF@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
HKD3_k127_4080305_4	1123248.KB893316_gene4532	3.805e-84	287.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1J0JU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD3_k127_4108188_3	925409.KI911562_gene61	3.236e-114	378.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1IQCX@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HKD3_k127_4108188_0	1267211.KI669560_gene2545	4.256e-267	829.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
HKD3_k127_4108188_5	1123248.KB893324_gene1764	2.84e-42	172.0	28ICP@1|root,314Q6@2|Bacteria,4PIZD@976|Bacteroidetes,1IZ0B@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4108188_1	714943.Mucpa_5139	7.596e-188	597.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,1IPJ3@117747|Sphingobacteriia	976|Bacteroidetes	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD3_k127_4108188_2	714943.Mucpa_5140	7.445e-157	501.0	COG2334@1|root,COG2334@2|Bacteria,4NITA@976|Bacteroidetes,1IRG4@117747|Sphingobacteriia	976|Bacteroidetes	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4108188_4	714943.Mucpa_5141	6.653e-108	357.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1IQXC@117747|Sphingobacteriia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
HKD3_k127_4108188_6	1121287.AUMU01000016_gene148	1.455e-06	56.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,3ZNXS@59732|Chryseobacterium	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4127_2	1123248.KB893348_gene214	3.921e-196	616.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HKD3_k127_4127_3	1123248.KB893348_gene215	1.578e-69	241.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_4127_5	925409.KI911562_gene903	7.331e-27	117.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	skp	GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD3_k127_4127_4	1123248.KB893348_gene261	2.111e-51	188.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes,1J0EF@117747|Sphingobacteriia	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD3_k127_4127_1	929562.Emtol_0758	2.239e-229	733.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD3_k127_4127_0	925409.KI911562_gene1107	1.369e-233	729.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
HKD3_k127_4177366_0	1168034.FH5T_01920	1.49e-312	971.0	COG3408@1|root,COG3408@2|Bacteria,4NFHH@976|Bacteroidetes,2FQTQ@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
HKD3_k127_419192_2	1123248.KB893329_gene4481	1.548e-40	155.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IS84@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HKD3_k127_419192_1	485918.Cpin_6913	5.557e-118	389.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1J0PK@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_419192_0	1123248.KB893385_gene4872	7.4e-286	898.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
HKD3_k127_4269252_4	700598.Niako_4399	8.532e-75	271.0	COG4977@1|root,COG4977@2|Bacteria,4PKR2@976|Bacteroidetes,1J0NT@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_4269252_0	1392489.JPOL01000002_gene3021	8.216e-263	821.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1HWTC@117743|Flavobacteriia,2XJW2@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_4269252_1	518766.Rmar_2440	6.027e-180	571.0	COG2152@1|root,COG2152@2|Bacteria,4NGA2@976|Bacteroidetes	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
HKD3_k127_4269252_3	925409.KI911562_gene1639	3.364e-87	301.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,1IQ0H@117747|Sphingobacteriia	976|Bacteroidetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HKD3_k127_4269252_5	1123248.KB893326_gene1298	5.743e-60	214.0	COG2755@1|root,COG2755@2|Bacteria,4NMGQ@976|Bacteroidetes,1IXI7@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_4269252_2	485917.Phep_3881	2.64e-123	404.0	COG1609@1|root,COG1609@2|Bacteria,4NFB7@976|Bacteroidetes,1IRES@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
HKD3_k127_4269252_7	1123008.KB905695_gene2500	1.459e-05	53.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Hepar_II_III,Hepar_II_III_N,OprD
HKD3_k127_4269252_6	497964.CfE428DRAFT_3107	9.436e-57	219.0	COG1028@1|root,COG2273@1|root,COG1028@2|Bacteria,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.73	ko:K01216	-	-	-	-	ko00000,ko01000	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_16
HKD3_k127_4284346_1	1434325.AZQN01000004_gene1778	9.394e-56	200.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,47JBH@768503|Cytophagia	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
HKD3_k127_4284346_0	700598.Niako_6638	5.523e-100	341.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1INKX@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD3_k127_4284346_2	925409.KI911562_gene1607	8.15e-31	132.0	COG0810@1|root,COG0860@1|root,COG4219@1|root,COG0810@2|Bacteria,COG0860@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1IXPP@117747|Sphingobacteriia	976|Bacteroidetes	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Peptidase_M56,TonB_C
HKD3_k127_4379097_0	925409.KI911562_gene3036	0.0	1248.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_4379097_5	700598.Niako_7017	3.74e-51	190.0	COG0664@1|root,COG0664@2|Bacteria,4NQ1A@976|Bacteroidetes,1IY7M@117747|Sphingobacteriia	976|Bacteroidetes	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_4379097_4	485918.Cpin_6525	8.295e-73	254.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1IR1A@117747|Sphingobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
HKD3_k127_4379097_1	925409.KI911562_gene2428	2.539e-193	610.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1IV68@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
HKD3_k127_4379097_3	1123248.KB893340_gene2662	9.011e-93	319.0	COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,1IQ1K@117747|Sphingobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_4379097_2	700598.Niako_1810	4.36e-107	365.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1IR01@117747|Sphingobacteriia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HKD3_k127_4379097_6	468059.AUHA01000003_gene1903	6.815e-35	138.0	2D0AC@1|root,32T87@2|Bacteria,4NSVN@976|Bacteroidetes,1ITAV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4412650_2	1341181.FLJC2902T_03220	4.144e-79	267.0	2C57D@1|root,2Z7RS@2|Bacteria,4NEKN@976|Bacteroidetes,1HXT2@117743|Flavobacteriia,2NUVZ@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
HKD3_k127_4412650_3	1296415.JACC01000043_gene86	1.354e-40	156.0	COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes,1I2TS@117743|Flavobacteriia,2YJBC@290174|Aquimarina	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_4412650_0	700598.Niako_1949	4.712e-171	542.0	COG3507@1|root,COG3507@2|Bacteria,4NEIZ@976|Bacteroidetes,1IRD7@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
HKD3_k127_4412650_5	1111730.ATTM01000007_gene2375	3.932e-09	70.0	COG3391@1|root,COG4935@1|root,COG3391@2|Bacteria,COG4935@2|Bacteria,4PPGZ@976|Bacteroidetes,1IKMN@117743|Flavobacteriia,2NV5K@237|Flavobacterium	976|Bacteroidetes	O	Reprolysin (M12B) family zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	CUB,Reprolysin_5
HKD3_k127_4412650_4	1380384.JADN01000003_gene759	9.003e-36	156.0	COG3858@1|root,COG3858@2|Bacteria,4NJZ6@976|Bacteroidetes,1I1G8@117743|Flavobacteriia	976|Bacteroidetes	S	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Glyco_hydro_18,Laminin_G_3
HKD3_k127_4412650_1	1123248.KB893332_gene2278	1.75e-115	380.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_441653_4	1380600.AUYN01000009_gene1141	2.844e-12	67.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_441653_0	762903.Pedsa_0636	1.425e-168	535.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,1IRGT@117747|Sphingobacteriia	976|Bacteroidetes	C	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
HKD3_k127_441653_1	1267211.KI669560_gene1001	4.101e-164	524.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1IQPQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HKD3_k127_441653_2	1122179.KB890455_gene3038	2.942e-160	518.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes	976|Bacteroidetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_441653_3	760192.Halhy_0433	5.327e-60	213.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1IS5G@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_443385_2	1123248.KB893329_gene4480	3.228e-81	275.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,1IWHH@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD3_k127_443385_4	700598.Niako_5511	4.757e-44	167.0	2EB10@1|root,3351W@2|Bacteria,4NV9Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_443385_3	1122605.KB893630_gene4082	1.458e-63	224.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1IS44@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_443385_0	925409.KI911562_gene1612	2.255e-227	713.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1IQ8J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD3_k127_443385_1	485918.Cpin_6911	2.966e-102	337.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQ3T@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_443385_5	1123248.KB893318_gene4181	1.974e-09	59.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1IPSH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4434724_6	1121870.AUAA01000048_gene2101	6.643e-62	238.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia,3HGTX@358033|Chryseobacterium	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Endonuclease_1,LTD,fn3
HKD3_k127_4434724_7	234267.Acid_5965	1.538e-52	209.0	COG2374@1|root,COG3386@1|root,COG2374@2|Bacteria,COG3386@2|Bacteria,3Y6HZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF1573,Exo_endo_phos,LTD
HKD3_k127_4434724_3	925409.KI911562_gene444	5.08e-141	460.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IPFH@117747|Sphingobacteriia	976|Bacteroidetes	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
HKD3_k127_4434724_2	1267211.KI669560_gene2510	1.109e-205	649.0	28II1@1|root,2Z8J7@2|Bacteria,4NFJH@976|Bacteroidetes,1IRA3@117747|Sphingobacteriia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
HKD3_k127_4434724_0	1120965.AUBV01000012_gene1439	0.0	1318.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47YGS@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_4434724_1	1122605.KB893646_gene110	8.583e-210	655.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD3_k127_4434724_9	749927.AMED_4013	6.936e-30	130.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4EAP9@85010|Pseudonocardiales	201174|Actinobacteria	M	Male sterility protein	-	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
HKD3_k127_4434724_5	471852.Tcur_2088	1.77e-62	234.0	COG0318@1|root,COG1215@1|root,COG0318@2|Bacteria,COG1215@2|Bacteria,2IB3B@201174|Actinobacteria,4EMTB@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_4434724_4	290399.Arth_2954	4.656e-63	230.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria	201174|Actinobacteria	I	synthase III	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD3_k127_4434724_10	1237500.ANBA01000017_gene1650	1.995e-20	102.0	COG3396@1|root,COG3396@2|Bacteria,2GMBI@201174|Actinobacteria,4EII9@85012|Streptosporangiales	201174|Actinobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
HKD3_k127_4434724_8	1123277.KB893172_gene837	2.655e-41	164.0	COG2867@1|root,COG2867@2|Bacteria,4NNHS@976|Bacteroidetes,47P7J@768503|Cytophagia	976|Bacteroidetes	I	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
HKD3_k127_4464428_2	1267211.KI669560_gene580	1.545e-49	180.0	COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,1ITGU@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD3_k127_4464428_0	925409.KI911562_gene619	3.31e-74	257.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1IY4A@117747|Sphingobacteriia	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD3_k127_4464428_3	925409.KI911562_gene620	1.518e-42	159.0	2DNMN@1|root,32Y54@2|Bacteria,4NW3V@976|Bacteroidetes,1IYIN@117747|Sphingobacteriia	976|Bacteroidetes	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
HKD3_k127_4464428_1	519989.ECTPHS_12697	1.499e-57	201.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1WXVD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
HKD3_k127_4523961_1	1123277.KB893197_gene6098	1.291e-41	158.0	COG2972@1|root,COG2972@2|Bacteria,4P15Q@976|Bacteroidetes,47UH7@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_4523961_0	1185876.BN8_01080	1.395e-83	285.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47M8M@768503|Cytophagia	976|Bacteroidetes	K	Two component transcriptional regulator, LytTR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_4523961_3	1123277.KB893173_gene1726	2.731e-15	86.0	2DWPY@1|root,32V1Y@2|Bacteria,4NU0T@976|Bacteroidetes,47VZ6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4523961_2	504472.Slin_2089	5.44e-33	137.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,47PTG@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
HKD3_k127_4613858_2	1267211.KI669560_gene1070	2.685e-220	691.0	COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,1IPVX@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,BNR_assoc_N
HKD3_k127_4613858_3	485917.Phep_3254	3.006e-205	651.0	COG2271@1|root,COG2271@2|Bacteria,4NFKX@976|Bacteroidetes,1IRIE@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_4613858_5	1267211.KI669560_gene1068	3.189e-100	339.0	COG3055@1|root,COG3055@2|Bacteria,4NKFS@976|Bacteroidetes,1ISBA@117747|Sphingobacteriia	976|Bacteroidetes	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4
HKD3_k127_4613858_4	1267211.KI669560_gene1067	1.718e-153	490.0	COG0329@1|root,COG0329@2|Bacteria,4NHBA@976|Bacteroidetes,1IR29@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	4.1.3.3,4.2.1.41,4.3.3.7	ko:K01639,ko:K01707,ko:K01714	ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R02279,R10147	RC00159,RC00600,RC00678,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_4613858_1	1267211.KI669560_gene1066	9.147e-268	833.0	COG1395@1|root,COG1395@2|Bacteria,4P0EC@976|Bacteroidetes,1IVGE@117747|Sphingobacteriia	976|Bacteroidetes	K	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_4613858_0	1267211.KI669560_gene1065	0.0	1491.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IPDC@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_4613858_7	1267211.KI669560_gene1064	3.686e-91	336.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_4613858_6	1267211.KI669560_gene1063	8.452e-95	312.0	COG2186@1|root,COG2186@2|Bacteria,4NEUP@976|Bacteroidetes,1IPCW@117747|Sphingobacteriia	976|Bacteroidetes	K	GntR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HKD3_k127_46170_1	700598.Niako_0329	6.191e-226	706.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1IR18@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HKD3_k127_46170_2	925409.KI911562_gene2787	8.927e-114	375.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1INM6@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD3_k127_46170_3	1267211.KI669560_gene1398	8.714e-46	175.0	COG3595@1|root,COG3595@2|Bacteria,4NIA2@976|Bacteroidetes,1ITRH@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_46170_0	1267211.KI669560_gene1397	1.184e-258	819.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,1J0SA@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_46170_4	204669.Acid345_4739	5.413e-12	72.0	2EBP0@1|root,335P6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4617134_1	1042376.AFPK01000038_gene578	1.936e-101	338.0	COG4124@1|root,COG4124@2|Bacteria,4PPF2@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
HKD3_k127_4617134_2	1185876.BN8_01390	6.57e-24	111.0	COG0590@1|root,COG0590@2|Bacteria,4NQ98@976|Bacteroidetes,47QRH@768503|Cytophagia	976|Bacteroidetes	FJ	tRNA wobble adenosine to inosine editing	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4617134_0	1267211.KI669560_gene2734	0.0	1095.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_46257_2	1267211.KI669560_gene2219	2.191e-116	379.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1IQTX@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD3_k127_46257_1	700598.Niako_4140	1.688e-136	441.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HKD3_k127_46257_4	925409.KI911562_gene1984	2.327e-79	269.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1IRH8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
HKD3_k127_46257_3	1267211.KI669560_gene2224	1.292e-96	323.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IPQ2@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_46257_0	1267211.KI669560_gene1616	7.921e-211	663.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HKD3_k127_46257_5	925409.KI911562_gene2267	1.656e-69	238.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HKD3_k127_46257_6	700598.Niako_2014	5.138e-68	243.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,1ITG6@117747|Sphingobacteriia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
HKD3_k127_46257_7	700598.Niako_1561	4.43e-57	215.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,1IYEN@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_46257_8	285535.JOEY01000035_gene3715	0.0003638	46.0	COG0477@1|root,COG0477@2|Bacteria,2H6BY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_4640696_1	925409.KI911562_gene1221	7.681e-172	546.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1IQ4I@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
HKD3_k127_4640696_0	468059.AUHA01000002_gene745	3.193e-185	582.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1IUY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_4651629_0	700598.Niako_6431	3.812e-245	769.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD3_k127_4651629_3	591001.Acfer_0151	9.733e-06	58.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,4H3RJ@909932|Negativicutes	909932|Negativicutes	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
HKD3_k127_4651629_1	1122605.KB893647_gene460	1.421e-184	600.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1INX6@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HKD3_k127_4651629_2	760192.Halhy_2531	6.144e-156	504.0	COG0531@1|root,COG0531@2|Bacteria,4NICM@976|Bacteroidetes,1IQNC@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_4735518_2	1239962.C943_03733	4.239e-104	351.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4P3P6@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4735518_0	925409.KI911562_gene2072	7.681e-152	490.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1IQMR@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
HKD3_k127_4735518_4	926556.Echvi_0679	2.234e-58	218.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes	976|Bacteroidetes	N	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
HKD3_k127_4735518_3	929713.NIASO_03880	5.191e-63	224.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1ITW4@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
HKD3_k127_4735518_1	700598.Niako_0428	3.057e-105	343.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_4756521_1	925409.KI911562_gene1095	1.528e-77	264.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1INPG@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2812 DNA polymerase III, gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
HKD3_k127_4756521_2	925409.KI911562_gene1096	2.62e-77	261.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1ISUU@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD3_k127_4756521_0	700598.Niako_5799	7.775e-86	295.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1ISIT@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_478871_5	1123248.KB893348_gene241	3.167e-19	89.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1INSY@117747|Sphingobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HKD3_k127_478871_4	1189612.A33Q_1536	2.044e-21	98.0	2DMNP@1|root,32SQ4@2|Bacteria,4NT2A@976|Bacteroidetes,47WCH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_478871_2	1239962.C943_03523	4.574e-33	133.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
HKD3_k127_478871_1	1239962.C943_01413	9.111e-39	151.0	2ANDI@1|root,31DC5@2|Bacteria,4NSSW@976|Bacteroidetes,47PXY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
HKD3_k127_478871_3	1121887.AUDK01000015_gene863	1.539e-31	124.0	COG3655@1|root,COG3655@2|Bacteria,4NUP7@976|Bacteroidetes,1I506@117743|Flavobacteriia,2NX1X@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
HKD3_k127_478871_0	1250278.JQNQ01000001_gene2429	4.706e-113	371.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_4830264_13	1168034.FH5T_12365	2.526e-16	86.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,2FMUQ@200643|Bacteroidia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
HKD3_k127_4830264_1	1123248.KB893330_gene392	4.248e-154	492.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1IX1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_4830264_0	1123248.KB893314_gene3687	4.702e-308	961.0	COG0448@1|root,COG0448@2|Bacteria,4PKFG@976|Bacteroidetes,1IPMM@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
HKD3_k127_4830264_9	929556.Solca_1796	1.468e-41	160.0	2ATWF@1|root,31JFP@2|Bacteria,4NT3Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4830264_11	1121094.KB894645_gene231	1.891e-31	129.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,2FM3K@200643|Bacteroidia,4ANJB@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HKD3_k127_4830264_10	1089550.ATTH01000001_gene1958	2.231e-32	130.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1FJI3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
HKD3_k127_4830264_6	925409.KI911562_gene2539	5.292e-52	194.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_4830264_3	1122605.KB893649_gene3840	2.221e-83	277.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1IRUT@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HKD3_k127_4830264_2	1123248.KB893381_gene1097	3.696e-123	397.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1IPE4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HKD3_k127_4830264_4	1122605.KB893649_gene3838	2.02e-78	267.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1IS1J@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HKD3_k127_4830264_8	929713.NIASO_11230	5.426e-50	180.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1ISEQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HKD3_k127_4830264_12	1123234.AUKI01000016_gene3044	1.009e-30	126.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
HKD3_k127_4830264_7	485918.Cpin_6003	1.306e-51	191.0	COG0664@1|root,COG0664@2|Bacteria,4NPIM@976|Bacteroidetes,1ITMR@117747|Sphingobacteriia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_4830264_5	714943.Mucpa_6677	9.154e-64	226.0	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,1ISQ6@117747|Sphingobacteriia	976|Bacteroidetes	C	nitroreductase	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD3_k127_4836656_0	1123248.KB893314_gene3581	2.126e-134	436.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HKD3_k127_4836656_1	700598.Niako_4415	7.793e-108	364.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1IP77@117747|Sphingobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD3_k127_4841655_1	925409.KI911562_gene1384	7.022e-120	392.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1IQ4Y@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_4841655_0	929713.NIASO_07075	3.279e-184	586.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,1IQG4@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_4841655_2	485918.Cpin_2904	2.796e-30	121.0	COG3291@1|root,COG3291@2|Bacteria,4NV8C@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD3_k127_4849450_0	1122605.KB893646_gene175	1.097e-294	910.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HKD3_k127_4849450_5	1453505.JASY01000001_gene3641	4.591e-07	56.0	COG3655@1|root,COG3655@2|Bacteria,4PPWB@976|Bacteroidetes,1I9B8@117743|Flavobacteriia,2P0WN@237|Flavobacterium	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD3_k127_4849450_3	102125.Xen7305DRAFT_00032300	2.37e-24	116.0	COG0633@1|root,COG0633@2|Bacteria,1G6TC@1117|Cyanobacteria,3VJY8@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K02639	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Fer2
HKD3_k127_4849450_2	1123248.KB893319_gene4004	3.499e-29	117.0	2BZQY@1|root,2ZVH4@2|Bacteria,4P73I@976|Bacteroidetes,1IZGJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4849450_4	1250006.JHZZ01000001_gene1660	1.763e-19	103.0	2EZ38@1|root,33S9G@2|Bacteria,4P0FQ@976|Bacteroidetes,1I8CU@117743|Flavobacteriia,3VWYX@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4849450_1	1042376.AFPK01000038_gene582	4.453e-196	629.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HYXG@117743|Flavobacteriia	976|Bacteroidetes	GM	Glycosyl transferase family 21	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_hydro_26,Glyco_hydro_2_C,Glyco_transf_21
HKD3_k127_4855975_1	700598.Niako_3260	2.848e-112	374.0	COG0628@1|root,COG0628@2|Bacteria,4NPIX@976|Bacteroidetes,1IVAD@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_4855975_0	925409.KI911562_gene2250	9.337e-143	470.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,1IR4H@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HKD3_k127_4862209_0	929556.Solca_0377	1.96e-228	713.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1IPSV@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_4862209_2	929713.NIASO_07860	2.41e-126	416.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD3_k127_4862209_1	700598.Niako_0117	2.384e-206	649.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HKD3_k127_4873525_2	1121957.ATVL01000007_gene1815	7.597e-14	76.0	COG3291@1|root,COG3391@1|root,COG3934@1|root,COG4719@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3934@2|Bacteria,COG4719@2|Bacteria,4NNAV@976|Bacteroidetes,47YQ3@768503|Cytophagia	976|Bacteroidetes	G	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HKD3_k127_4873525_0	1123248.KB893348_gene233	1.385e-194	616.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_4873525_1	925409.KI911562_gene442	3.44e-76	259.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_4880011_3	1191523.MROS_2264	2.476e-37	143.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porG	-	1.2.7.3,1.2.7.7	ko:K00177,ko:K00187	ko00020,ko00280,ko00720,ko01100,ko01120,ko01200,map00020,map00280,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197,R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
HKD3_k127_4880011_6	313595.P700755_002947	6.586e-12	75.0	COG3548@1|root,COG3548@2|Bacteria,4NW8Z@976|Bacteroidetes,1I72V@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD3_k127_4880011_1	1122605.KB893625_gene2098	6.474e-88	297.0	28I6D@1|root,2Z89E@2|Bacteria,4NIIX@976|Bacteroidetes,1IPPJ@117747|Sphingobacteriia	976|Bacteroidetes	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
HKD3_k127_4880011_0	1122605.KB893649_gene3854	4.608e-160	513.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,1INVX@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
HKD3_k127_4880011_4	888727.HMPREF9092_1642	8.757e-22	101.0	2BPEU@1|root,32I71@2|Bacteria,1VDVA@1239|Firmicutes,25BDW@186801|Clostridia	186801|Clostridia	S	HIRAN	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
HKD3_k127_4880011_5	596327.PORUE0001_1786	1.528e-14	87.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
HKD3_k127_4880011_2	1227739.Hsw_2966	1.762e-64	233.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_4890166_6	700598.Niako_5039	1.682e-15	77.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1IQ41@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD3_k127_4890166_7	667015.Bacsa_3301	2.914e-08	65.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4ANSE@815|Bacteroidaceae	976|Bacteroidetes	KT	COG NOG25147 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
HKD3_k127_4890166_1	700598.Niako_7025	2.847e-182	601.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1IUYM@117747|Sphingobacteriia	976|Bacteroidetes	G	Galactose mutarotase-like	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31
HKD3_k127_4890166_4	1185876.BN8_02353	2.932e-63	221.0	COG1051@1|root,COG1051@2|Bacteria,4NNUR@976|Bacteroidetes,47PU7@768503|Cytophagia	976|Bacteroidetes	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD3_k127_4890166_3	1123248.KB893319_gene4000	7.251e-85	288.0	28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,1IRT2@117747|Sphingobacteriia	976|Bacteroidetes	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
HKD3_k127_4890166_0	700598.Niako_1436	1.296e-190	605.0	COG0038@1|root,COG0038@2|Bacteria,4NEIA@976|Bacteroidetes,1IP55@117747|Sphingobacteriia	976|Bacteroidetes	P	Chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
HKD3_k127_4890166_2	485917.Phep_2441	5.093e-94	319.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IQN9@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
HKD3_k127_4890166_5	1239415.CM001837_gene1724	1.063e-15	83.0	COG3708@1|root,COG3708@2|Bacteria,4NQ46@976|Bacteroidetes,1I45F@117743|Flavobacteriia,37F2R@326319|Dokdonia	976|Bacteroidetes	K	Integron-associated effector binding protein	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
HKD3_k127_4896936_0	1123248.KB893322_gene627	1.679e-153	497.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1IX4W@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_4896936_2	700598.Niako_1106	1.174e-77	263.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1IQD8@117747|Sphingobacteriia	976|Bacteroidetes	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HKD3_k127_4896936_1	1123248.KB893322_gene626	2.579e-111	366.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_4908893_1	925409.KI911562_gene925	1.955e-122	401.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1INUR@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
HKD3_k127_4908893_0	1267211.KI669560_gene665	9.814e-276	857.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1IQ8E@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
HKD3_k127_4911635_8	1123248.KB893331_gene3753	2.392e-95	321.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1INYY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
HKD3_k127_4911635_1	1123248.KB893386_gene1829	3.491e-270	839.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD3_k127_4911635_13	700598.Niako_6678	1.855e-64	231.0	COG1560@1|root,COG1560@2|Bacteria,4NPAI@976|Bacteroidetes,1J0BY@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HKD3_k127_4911635_12	925409.KI911562_gene415	1.47e-71	254.0	COG1560@1|root,COG1560@2|Bacteria,4NPAI@976|Bacteroidetes,1J0BY@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HKD3_k127_4911635_2	925409.KI911562_gene414	1.55e-202	641.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_4911635_20	485918.Cpin_0945	5.575e-30	122.0	COG0640@1|root,COG0640@2|Bacteria,4P4RQ@976|Bacteroidetes,1IYKV@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
HKD3_k127_4911635_18	700598.Niako_6674	3.346e-45	175.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1IRWM@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
HKD3_k127_4911635_21	709986.Deima_1112	1.233e-21	103.0	COG1250@1|root,COG1250@2|Bacteria,1WIPA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_4911635_16	700598.Niako_6672	6.179e-50	180.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1ISZW@117747|Sphingobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HKD3_k127_4911635_0	925409.KI911562_gene408	0.0	1771.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD3_k127_4911635_11	946077.W5A_06446	8.366e-82	286.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1I95J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4911635_7	1123248.KB893316_gene4662	2.583e-96	320.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IWQ3@117747|Sphingobacteriia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_4911635_6	946077.W5A_06436	2.498e-96	331.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1HXJE@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
HKD3_k127_4911635_4	946077.W5A_06431	7.525e-111	371.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1I6UH@117743|Flavobacteriia	976|Bacteroidetes	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD3_k127_4911635_10	1237149.C900_02167	2.671e-87	295.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
HKD3_k127_4911635_17	700598.Niako_4053	1.328e-47	177.0	COG5263@1|root,COG5263@2|Bacteria,4PN8Y@976|Bacteroidetes,1J0PQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
HKD3_k127_4911635_5	509635.N824_27690	3.198e-97	332.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1IPFY@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
HKD3_k127_4911635_19	880071.Fleli_0042	5.538e-38	151.0	COG2340@1|root,COG2340@2|Bacteria,4NW16@976|Bacteroidetes,47SFM@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
HKD3_k127_4911635_14	485918.Cpin_4197	1.883e-56	227.0	COG4733@1|root,COG4733@2|Bacteria,4PKY7@976|Bacteroidetes,1J0NC@117747|Sphingobacteriia	976|Bacteroidetes	O	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PPC,Reprolysin_4,fn3
HKD3_k127_4911635_3	984262.SGRA_2537	8.287e-155	533.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_4911635_9	700598.Niako_6719	1.693e-93	314.0	COG3023@1|root,COG3023@2|Bacteria,4NE38@976|Bacteroidetes,1INQE@117747|Sphingobacteriia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	amiD	-	3.5.1.28	ko:K01447,ko:K11066	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1
HKD3_k127_4911635_15	1267211.KI669560_gene58	2.496e-54	198.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,1IT4J@117747|Sphingobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD3_k127_4941103_3	1122918.KB907246_gene1422	2.971e-12	72.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HCT0@91061|Bacilli,27496@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
HKD3_k127_4941103_1	761193.Runsl_0865	1.095e-118	396.0	COG2327@1|root,COG2327@2|Bacteria,4NEVH@976|Bacteroidetes,47NW8@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
HKD3_k127_4941103_0	1185876.BN8_02000	3.756e-175	565.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_4941103_2	1123277.KB893183_gene121	6.021e-19	89.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47MQK@768503|Cytophagia	976|Bacteroidetes	P	Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_4945292_5	1150600.ADIARSV_3918	2.759e-144	465.0	COG1216@1|root,COG1216@2|Bacteria,4NGEQ@976|Bacteroidetes,1IPXG@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_4945292_10	700598.Niako_2721	1.317e-74	261.0	COG0392@1|root,COG0392@2|Bacteria,4NMZ1@976|Bacteroidetes,1IRX8@117747|Sphingobacteriia	976|Bacteroidetes	O	Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_4945292_8	1123248.KB893315_gene3021	2.225e-100	336.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_4945292_3	1267211.KI669560_gene2676	7.113e-230	741.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_4945292_2	1267211.KI669560_gene2676	2.138e-238	766.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_4945292_12	1123248.KB893315_gene3023	2.253e-65	235.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1IXNU@117747|Sphingobacteriia	976|Bacteroidetes	I	Ndr family	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD3_k127_4945292_4	925409.KI911562_gene1488	1.275e-154	504.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1IQGK@117747|Sphingobacteriia	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
HKD3_k127_4945292_7	761193.Runsl_5260	5.583e-103	340.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD3_k127_4945292_17	504487.JCM19302_3076	8.908e-29	119.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1I1ZF@117743|Flavobacteriia	976|Bacteroidetes	H	synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD3_k127_4945292_11	929713.NIASO_19245	1.74e-65	225.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1ISCG@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydrobiopterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD3_k127_4945292_16	1131730.BAVI_22513	7.474e-46	171.0	COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,1ZH0A@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
HKD3_k127_4945292_13	991.IW20_08310	4.474e-59	209.0	COG1670@1|root,COG1670@2|Bacteria,4NQ4Z@976|Bacteroidetes,1I4QQ@117743|Flavobacteriia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
HKD3_k127_4945292_9	493475.GARC_3378	1.948e-75	259.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S6G7@1236|Gammaproteobacteria,468G7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
HKD3_k127_4945292_1	1122179.KB890431_gene4241	6.852e-259	808.0	COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4945292_0	1123248.KB893322_gene595	0.0	2775.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1INS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
HKD3_k127_4945292_14	925409.KI911562_gene1498	9.795e-59	210.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1IQBR@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HKD3_k127_4945292_15	1122176.KB903551_gene4227	3.549e-52	190.0	COG1225@1|root,COG1225@2|Bacteria,4NNHI@976|Bacteroidetes,1ISKK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD3_k127_4945292_6	700598.Niako_4487	4.171e-116	387.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,1J0IU@117747|Sphingobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HKD3_k127_4952061_1	760192.Halhy_1114	2.006e-112	369.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1INPD@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD3_k127_4952061_0	1267211.KI669560_gene1251	2.761e-191	610.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1IPDB@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD3_k127_4952061_2	1123248.KB893326_gene1293	3.547e-108	357.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_4960094_17	925409.KI911562_gene1086	1.127e-19	91.0	2E473@1|root,32Z2Z@2|Bacteria,4NVZ4@976|Bacteroidetes,1IVB3@117747|Sphingobacteriia	976|Bacteroidetes	S	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE
HKD3_k127_4960094_7	1122605.KB893646_gene69	2.889e-194	619.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1IREB@117747|Sphingobacteriia	976|Bacteroidetes	M	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_4960094_3	468059.AUHA01000004_gene2237	0.0	1076.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1J0ID@117747|Sphingobacteriia	976|Bacteroidetes	H	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_4960094_6	925409.KI911562_gene1082	1.184e-288	916.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1IQ6P@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
HKD3_k127_4960094_10	925409.KI911562_gene1081	5.151e-116	378.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1IP93@117747|Sphingobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD3_k127_4960094_5	1123248.KB893386_gene1852	8.413e-299	931.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HKD3_k127_4960094_13	1122605.KB893646_gene80	1.906e-69	242.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1ISUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
HKD3_k127_4960094_8	925409.KI911562_gene1077	6.844e-173	546.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1IQCT@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_4960094_11	1270196.JCKI01000009_gene3386	2.504e-86	297.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IY37@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD3_k127_4960094_4	485918.Cpin_0566	1.032e-312	986.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1IQK2@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_4960094_9	1122176.KB903539_gene1338	9.583e-171	550.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,1IRFK@117747|Sphingobacteriia	976|Bacteroidetes	M	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_4960094_0	925409.KI911562_gene1388	0.0	1288.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_4960094_15	925409.KI911562_gene1390	1.592e-50	191.0	2F80M@1|root,340E7@2|Bacteria,4P4VX@976|Bacteroidetes,1IYG6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4960094_1	925409.KI911562_gene1389	0.0	1255.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IWKA@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
HKD3_k127_4960094_2	925409.KI911562_gene1393	0.0	1088.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IPYF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	kojP	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
HKD3_k127_4960094_16	929713.NIASO_13915	1.795e-21	102.0	2EHHG@1|root,33B9E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4960094_12	1267211.KI669560_gene1027	4.595e-76	262.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_4969304_7	1267211.KI669560_gene1535	4.228e-51	183.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
HKD3_k127_4969304_2	700598.Niako_2090	5.404e-128	414.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_4969304_6	1454007.JAUG01000072_gene4100	8.479e-59	213.0	COG0545@1|root,COG0545@2|Bacteria,4NJKK@976|Bacteroidetes,1IT5P@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	fkpB	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
HKD3_k127_4969304_5	925409.KI911562_gene2100	1.312e-64	225.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1ISRY@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_4969304_0	760192.Halhy_5983	1.717e-200	638.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_4969304_4	1121285.AUFK01000014_gene2616	6.462e-88	296.0	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia,3ZNI2@59732|Chryseobacterium	976|Bacteroidetes	F	Purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_4969304_3	468059.AUHA01000002_gene911	4.226e-118	396.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4PHWS@976|Bacteroidetes,1IYDI@117747|Sphingobacteriia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD3_k127_4969304_1	1267211.KI669560_gene2216	6.419e-156	495.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1IR41@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
HKD3_k127_4980760_1	1123248.KB893386_gene1833	2.588e-192	608.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
HKD3_k127_4980760_2	485918.Cpin_0879	8.438e-91	304.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1IRD0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HKD3_k127_4980760_0	925409.KI911562_gene2325	1.368e-211	673.0	COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1IW0D@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_4989545_2	925409.KI911562_gene1108	1.269e-165	526.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1IP42@117747|Sphingobacteriia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HKD3_k127_4989545_1	1123248.KB893322_gene570	1.709e-172	554.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1IQB4@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
HKD3_k127_4989545_8	1267211.KI669560_gene655	4.522e-46	171.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1IT21@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD3_k127_4989545_3	929703.KE386491_gene2174	3.336e-112	367.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,47N6P@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD3_k127_4989545_5	742817.HMPREF9449_01266	2.793e-101	338.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,2FQT2@200643|Bacteroidia,22WM3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HKD3_k127_4989545_7	504472.Slin_1870	9.766e-69	237.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47P9R@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_4989545_4	926549.KI421517_gene3286	1.104e-111	367.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,47N6P@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD3_k127_4989545_9	762903.Pedsa_0634	2.315e-31	127.0	COG1765@1|root,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1ITTE@117747|Sphingobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	Fer4_19,OsmC
HKD3_k127_4989545_6	925409.KI911562_gene641	1.694e-78	266.0	COG0431@1|root,COG0431@2|Bacteria,4NNY7@976|Bacteroidetes	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD3_k127_4989545_0	925409.KI911562_gene640	0.0	1011.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
HKD3_k127_5011_2	1408433.JHXV01000012_gene3930	4.576e-22	104.0	COG2373@1|root,COG3391@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,4PKKG@976|Bacteroidetes,1IJBU@117743|Flavobacteriia	976|Bacteroidetes	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF4347,IgGFc_binding,SprB
HKD3_k127_5011_1	1122605.KB893629_gene4180	1.306e-34	135.0	COG3538@1|root,COG3538@2|Bacteria,4NGY6@976|Bacteroidetes,1IP3P@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP028846	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
HKD3_k127_5011_0	1166018.FAES_2159	5.117e-156	499.0	COG3538@1|root,COG3538@2|Bacteria,4NGY6@976|Bacteroidetes,47JIR@768503|Cytophagia	976|Bacteroidetes	S	Pfam:DUF1237	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
HKD3_k127_5022455_6	653733.Selin_1982	2.889e-51	186.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	hoxE	-	1.6.5.3	ko:K00334,ko:K05586	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HKD3_k127_5022455_0	857293.CAAU_0207	1.051e-215	682.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,36EMP@31979|Clostridiaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HKD3_k127_5022455_5	383372.Rcas_1366	2.815e-84	285.0	COG3383@1|root,COG3383@2|Bacteria,2G65A@200795|Chloroflexi,3769N@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,NADH-G_4Fe-4S_3
HKD3_k127_5022455_7	706587.Desti_0342	1.871e-50	185.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42PVF@68525|delta/epsilon subdivisions,2WPQM@28221|Deltaproteobacteria,2MS01@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase, 20	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
HKD3_k127_5022455_1	309799.DICTH_1783	2.654e-161	520.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
HKD3_k127_5022455_8	1173027.Mic7113_3068	2.338e-11	72.0	COG0680@1|root,COG0680@2|Bacteria,1G7PP@1117|Cyanobacteria,1HC58@1150|Oscillatoriales	1117|Cyanobacteria	C	hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5022455_2	925409.KI911562_gene2673	9.023e-136	436.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1IRN1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HKD3_k127_5022455_3	1267211.KI669560_gene1408	7.363e-133	428.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1IQKP@117747|Sphingobacteriia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD3_k127_5022455_4	925409.KI911562_gene2671	2.789e-92	310.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD3_k127_50299_6	797304.Natgr_3725	0.0002146	53.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD,PQQ_2,PQQ_3
HKD3_k127_50299_4	1267211.KI669560_gene110	2.277e-47	172.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1ITK5@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD3_k127_50299_2	929556.Solca_3634	9.783e-124	402.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
HKD3_k127_50299_0	1123276.KB893262_gene4085	5.74e-173	548.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,47M0B@768503|Cytophagia	976|Bacteroidetes	P	PFAM Sodium Bile acid symporter family	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
HKD3_k127_50299_3	925409.KI911562_gene440	3.989e-67	230.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
HKD3_k127_50299_5	1227739.Hsw_3187	1.938e-07	63.0	2DP36@1|root,330BY@2|Bacteria,4PMER@976|Bacteroidetes,47WPA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_50299_1	485918.Cpin_0696	9.506e-152	505.0	COG4206@1|root,COG4773@1|root,COG4206@2|Bacteria,COG4773@2|Bacteria,4PKFW@976|Bacteroidetes,1J0KS@117747|Sphingobacteriia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD3_k127_5058300_8	862515.HMPREF0658_1729	2.373e-16	79.0	COG1640@1|root,COG1640@2|Bacteria,4NF7Z@976|Bacteroidetes,2FMBZ@200643|Bacteroidia	976|Bacteroidetes	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	CBM_20,Glyco_hydro_77
HKD3_k127_5058300_2	991.IW20_04235	4.016e-138	446.0	COG1052@1|root,COG1052@2|Bacteria,4NF1R@976|Bacteroidetes,1HZJN@117743|Flavobacteriia,2NSY7@237|Flavobacterium	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_5058300_0	700598.Niako_4730	3.693e-205	673.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IPHQ@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
HKD3_k127_5058300_7	1123248.KB893321_gene559	2.075e-64	231.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,1IYJZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
HKD3_k127_5058300_6	929713.NIASO_01615	2.483e-79	271.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,1ISX6@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
HKD3_k127_5058300_3	1267211.KI669560_gene1420	5.012e-100	336.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1IXEE@117747|Sphingobacteriia	976|Bacteroidetes	E	GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
HKD3_k127_5058300_5	1123248.KB893317_gene4263	2.029e-93	314.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD3_k127_5058300_4	1267211.KI669560_gene1418	4.171e-98	327.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1IRFD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_5058300_1	925409.KI911562_gene2664	3.974e-160	507.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD3_k127_5075347_4	700598.Niako_6930	9.692e-45	168.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1ISJU@117747|Sphingobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HKD3_k127_5075347_3	1122605.KB893626_gene2546	2.871e-65	236.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_5075347_2	925409.KI911562_gene1213	5.851e-105	347.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1IS3D@117747|Sphingobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
HKD3_k127_5075347_1	700598.Niako_6934	3.118e-138	444.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_5075347_0	929713.NIASO_14175	4.64e-181	578.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD3_k127_5075347_5	925409.KI911562_gene1217	2.491e-08	55.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD3_k127_5084439_10	925409.KI911562_gene2981	9.586e-59	216.0	28KFX@1|root,2ZA1W@2|Bacteria,4P3W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5084439_7	760192.Halhy_5309	1.678e-119	394.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HKD3_k127_5084439_2	700598.Niako_5240	9.129e-190	599.0	COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes,1IR54@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	ce	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
HKD3_k127_5084439_4	700598.Niako_5229	2.11e-167	532.0	2DB9J@1|root,2Z7X1@2|Bacteria,4NGUY@976|Bacteroidetes,1IQJ4@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109
HKD3_k127_5084439_8	929556.Solca_2696	2.676e-74	256.0	COG2755@1|root,COG2755@2|Bacteria,4NPB3@976|Bacteroidetes,1J195@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_5084439_0	762903.Pedsa_0022	2.703e-205	646.0	COG0477@1|root,COG2814@2|Bacteria,4NG5F@976|Bacteroidetes	976|Bacteroidetes	EGP	Psort location CytoplasmicMembrane, score 10.00	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
HKD3_k127_5084439_9	714943.Mucpa_2717	1.64e-71	258.0	COG4632@1|root,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes,1ITPU@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,fn3
HKD3_k127_5084439_5	700598.Niako_5234	5.096e-145	473.0	COG4299@1|root,COG4299@2|Bacteria,4NJZJ@976|Bacteroidetes,1IR3E@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
HKD3_k127_5084439_6	929556.Solca_2701	3.783e-121	401.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HKD3_k127_5084439_3	1166018.FAES_5034	4.342e-178	576.0	COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,47P0A@768503|Cytophagia	976|Bacteroidetes	F	PFAM RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_5084439_1	1166018.FAES_5035	3.685e-195	626.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47KT8@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_5089219_2	485918.Cpin_3973	4.935e-31	123.0	COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,1ISQR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
HKD3_k127_5089219_1	1267211.KI669560_gene135	6.845e-90	302.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_16,TPR_8
HKD3_k127_5089219_3	1131812.JQMS01000001_gene1221	7.082e-13	74.0	COG2010@1|root,COG2010@2|Bacteria,4PCRX@976|Bacteroidetes,1IDAA@117743|Flavobacteriia,2NXVD@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5089219_0	925409.KI911562_gene1047	8.796e-287	895.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD3_k127_5097124_1	929713.NIASO_15890	6.301e-120	388.0	COG3507@1|root,COG3507@2|Bacteria,4NEMG@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43,fn3
HKD3_k127_5097124_0	1150600.ADIARSV_3651	0.0	1026.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1INUX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_5099703_2	929562.Emtol_3518	1.112e-170	551.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47MZ7@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD3_k127_5099703_14	927658.AJUM01000047_gene2788	9.36e-37	152.0	2E8XD@1|root,3337D@2|Bacteria,4NW3N@976|Bacteroidetes,2FVQT@200643|Bacteroidia,3XKVX@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5099703_9	927658.AJUM01000047_gene2789	6.597e-55	210.0	COG1520@1|root,COG1520@2|Bacteria,4PPAX@976|Bacteroidetes	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5099703_3	700598.Niako_5673	2.427e-132	430.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HKD3_k127_5099703_5	700598.Niako_5645	7.414e-103	341.0	COG1018@1|root,COG1018@2|Bacteria,4PN6Y@976|Bacteroidetes	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523,ko:K05784	ko00362,ko00364,ko00520,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00520,map00622,map01100,map01120,map01220	M00551	R03391,R03392,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00230,RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD3_k127_5099703_12	700598.Niako_7211	9.621e-40	151.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HKD3_k127_5099703_6	700598.Niako_7212	1.41e-92	308.0	COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,1IQCF@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HKD3_k127_5099703_8	700598.Niako_7213	1.75e-55	200.0	COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,1ISCW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HKD3_k127_5099703_0	700598.Niako_7214	1.483e-204	640.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
HKD3_k127_5099703_1	700598.Niako_7215	8.584e-188	592.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1INP9@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HKD3_k127_5099703_13	1237149.C900_05698	2.861e-38	153.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,47S2S@768503|Cytophagia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_5099703_7	700598.Niako_7216	1.753e-77	262.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
HKD3_k127_5099703_10	700598.Niako_7217	9.174e-51	186.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HKD3_k127_5099703_11	700598.Niako_7218	3.779e-42	156.0	COG0713@1|root,COG0713@2|Bacteria,4NSR8@976|Bacteroidetes,1ITB0@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HKD3_k127_5099703_4	700598.Niako_7219	1.797e-129	421.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQWT@117747|Sphingobacteriia	976|Bacteroidetes	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
HKD3_k127_5100042_5	746697.Aeqsu_1820	7.758e-26	113.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes,1I1N3@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
HKD3_k127_5100042_2	1454007.JAUG01000047_gene524	3.967e-196	622.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1IQ6C@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM coagulation factor 5 8 type	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C
HKD3_k127_5100042_1	925409.KI911562_gene723	0.0	1022.0	COG1434@1|root,COG1434@2|Bacteria,4NE96@976|Bacteroidetes,1IQHX@117747|Sphingobacteriia	976|Bacteroidetes	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
HKD3_k127_5100042_7	760192.Halhy_6067	4.66e-10	72.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,Laminin_G_3,SprB
HKD3_k127_5100042_3	1123248.KB893329_gene4495	1.717e-140	456.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1IW51@117747|Sphingobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HKD3_k127_5100042_0	925409.KI911562_gene578	0.0	1610.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD3_k127_5100042_4	1123248.KB893314_gene3422	6.364e-102	344.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
HKD3_k127_5100042_6	880071.Fleli_3016	1.43e-23	104.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47KE9@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_5116425_1	313603.FB2170_06630	4.624e-137	441.0	COG3387@1|root,COG3387@2|Bacteria,4NGFS@976|Bacteroidetes,1I0H9@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_36
HKD3_k127_5116425_0	313603.FB2170_06625	0.0	1150.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HZAM@117743|Flavobacteriia,2PIWJ@252356|Maribacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_5116425_2	869213.JCM21142_175	1.828e-92	317.0	COG0738@1|root,COG0738@2|Bacteria,4NEB2@976|Bacteroidetes	976|Bacteroidetes	G	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD3_k127_5116425_3	886379.AEWI01000004_gene879	2.896e-91	309.0	COG1940@1|root,COG1940@2|Bacteria,4NM8T@976|Bacteroidetes,2FSJS@200643|Bacteroidia,3XKR2@558415|Marinilabiliaceae	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD3_k127_5116425_4	869213.JCM21142_173	1.458e-87	295.0	COG2188@1|root,COG2188@2|Bacteria,4NFVY@976|Bacteroidetes,47P7I@768503|Cytophagia	976|Bacteroidetes	K	UTRA	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
HKD3_k127_5116425_8	1492737.FEM08_30550	4.397e-08	59.0	COG5434@1|root,COG5434@2|Bacteria,4NDWX@976|Bacteroidetes,1HZRR@117743|Flavobacteriia	976|Bacteroidetes	M	Parallel beta-helix repeats	glaB	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_5116425_7	929713.NIASO_04985	1.312e-09	64.0	COG5434@1|root,COG5434@2|Bacteria,4NDWX@976|Bacteroidetes	976|Bacteroidetes	M	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_5116425_6	886377.Murru_2355	6.575e-10	67.0	COG5661@1|root,COG5661@2|Bacteria,4NW11@976|Bacteroidetes,1I32R@117743|Flavobacteriia	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
HKD3_k127_5116425_5	2002.JOEQ01000017_gene7738	5.794e-12	68.0	COG3506@1|root,COG3506@2|Bacteria,2GJ86@201174|Actinobacteria,4ENWG@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
HKD3_k127_5118878_1	1123248.KB893381_gene1020	2.149e-202	647.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1IQAZ@117747|Sphingobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
HKD3_k127_5118878_0	925409.KI911562_gene1546	7.77e-292	903.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1IP4J@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HKD3_k127_5118878_5	1267211.KI669560_gene1295	1.508e-80	278.0	COG0412@1|root,COG0412@2|Bacteria,4NE8V@976|Bacteroidetes,1IS6I@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
HKD3_k127_5118878_4	925409.KI911562_gene1543	1.782e-106	352.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD3_k127_5118878_2	929562.Emtol_2665	1.966e-186	592.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47KVM@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD3_k127_5118878_3	1123248.KB893381_gene1032	8.265e-151	484.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,1IRDN@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
HKD3_k127_5118878_7	700598.Niako_4713	1.06e-14	75.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HKD3_k127_5133528_16	925409.KI911562_gene2689	2.243e-127	410.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_5133528_17	1123248.KB893332_gene2270	2.344e-119	396.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1IQGU@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HKD3_k127_5133528_13	925409.KI911562_gene2691	1.472e-138	448.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD3_k127_5133528_21	1123248.KB893316_gene4629	1e-88	304.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5133528_2	1123248.KB893370_gene5009	2.113e-273	852.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_5133528_24	700598.Niako_6519	6.653e-77	263.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1IV4X@117747|Sphingobacteriia	976|Bacteroidetes	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_5133528_4	388413.ALPR1_08308	1.167e-254	791.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_5133528_18	1305737.JAFX01000001_gene326	2.218e-99	329.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
HKD3_k127_5133528_30	1123248.KB893324_gene1684	3.095e-25	111.0	COG0607@1|root,COG0607@2|Bacteria,4PIDK@976|Bacteroidetes,1IZF6@117747|Sphingobacteriia	976|Bacteroidetes	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_5133528_33	755732.Fluta_2866	7.778e-07	53.0	2ABGN@1|root,310XN@2|Bacteria,4PFJR@976|Bacteroidetes,1I767@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5133528_31	1267211.KI669560_gene1582	3.634e-21	97.0	COG0607@1|root,COG0607@2|Bacteria,4PGNM@976|Bacteroidetes,1ITZD@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5133528_27	1267211.KI669560_gene1583	2.654e-38	149.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1J0R1@117747|Sphingobacteriia	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD3_k127_5133528_29	1313301.AUGC01000001_gene1815	4.65e-29	121.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes	976|Bacteroidetes	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_5133528_15	1267211.KI669560_gene1590	8.191e-133	438.0	COG3203@1|root,COG3203@2|Bacteria,4PMSP@976|Bacteroidetes	976|Bacteroidetes	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
HKD3_k127_5133528_20	153721.MYP_4368	1.245e-97	321.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_5133528_25	649349.Lbys_0966	3.246e-74	253.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_5133528_5	760192.Halhy_1959	1.954e-215	679.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IP4Z@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_5133528_9	1123277.KB893184_gene4200	3.042e-199	628.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_5133528_23	1123248.KB893314_gene3415	1.811e-79	272.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,1IQTT@117747|Sphingobacteriia	976|Bacteroidetes	J	Pseudouridine synthase	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HKD3_k127_5133528_12	700598.Niako_5548	7.679e-156	509.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
HKD3_k127_5133528_11	700598.Niako_5548	6.746e-158	516.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
HKD3_k127_5133528_8	925409.KI911562_gene264	1.759e-203	641.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1IQSD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_5133528_10	1123248.KB893314_gene3579	5.138e-163	527.0	COG0249@1|root,COG0249@2|Bacteria,4NEXA@976|Bacteroidetes,1IPHP@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
HKD3_k127_5133528_7	1492737.FEM08_24380	3.63e-208	657.0	COG4580@1|root,COG4580@2|Bacteria,4NHB0@976|Bacteroidetes,1ICN1@117743|Flavobacteriia,2NTIX@237|Flavobacterium	976|Bacteroidetes	G	LamB porin	-	-	-	ko:K02024	-	-	-	-	ko00000,ko02000	1.B.3.1.1	-	-	LamB
HKD3_k127_5133528_3	1123248.KB893337_gene2406	1.118e-255	796.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HKD3_k127_5133528_0	1123248.KB893316_gene4628	0.0	1097.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes,1IRMG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5133528_1	925409.KI911562_gene2502	4.555e-311	959.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1IP6T@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD3_k127_5133528_32	869210.Marky_2093	9.521e-11	74.0	29Y13@1|root,30JU0@2|Bacteria,1WKT1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5133528_22	925409.KI911562_gene2303	2.504e-84	284.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1INT9@117747|Sphingobacteriia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD3_k127_5133528_6	700598.Niako_0985	1.637e-214	670.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_5133528_19	925409.KI911562_gene2299	1.182e-97	325.0	COG2316@1|root,COG2316@2|Bacteria,4NIAC@976|Bacteroidetes	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD3_k127_5133528_14	925409.KI911562_gene2617	3.308e-137	447.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1IRZ6@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	nylB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD3_k127_5133528_28	1288963.ADIS_0320	6.849e-37	146.0	2E6P3@1|root,3319G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5133528_26	929562.Emtol_2395	7.391e-58	205.0	COG3963@1|root,COG3963@2|Bacteria,4PM0M@976|Bacteroidetes,47YK9@768503|Cytophagia	976|Bacteroidetes	I	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
HKD3_k127_5149354_3	929556.Solca_1389	9.509e-52	189.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_5149354_5	398720.MED217_01525	3.079e-06	51.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia,2XKCK@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
HKD3_k127_5149354_0	1123248.KB893386_gene1898	0.0	1167.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
HKD3_k127_5149354_4	485918.Cpin_0682	2.722e-10	62.0	COG2010@1|root,COG2010@2|Bacteria,4PJ6S@976|Bacteroidetes,1IZP1@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5149354_2	700598.Niako_1943	5.893e-96	327.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
HKD3_k127_5149354_1	929556.Solca_1394	6.607e-179	572.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
HKD3_k127_5178962_14	1123248.KB893370_gene5004	1.558e-23	104.0	2DPQE@1|root,332Z6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5178962_13	925409.KI911562_gene2188	1.784e-31	127.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,1ITYX@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HKD3_k127_5178962_7	925409.KI911562_gene2187	5.228e-87	299.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1IP2P@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD3_k127_5178962_9	1267211.KI669560_gene1655	2.898e-73	258.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1IPC8@117747|Sphingobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD3_k127_5178962_8	700598.Niako_1182	4.281e-76	260.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,1IXWW@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HKD3_k127_5178962_17	1454007.JAUG01000002_gene2895	1.712e-09	68.0	2A2ZH@1|root,30RE0@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD3_k127_5178962_1	1089547.KB913013_gene3785	2.441e-184	590.0	COG0521@1|root,COG0521@2|Bacteria,4NHNF@976|Bacteroidetes,47M4D@768503|Cytophagia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
HKD3_k127_5178962_0	1185876.BN8_04285	0.0	1092.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_5178962_6	925409.KI911562_gene2054	1.829e-98	327.0	COG1349@1|root,COG1349@2|Bacteria,4NE7U@976|Bacteroidetes,1IPYC@117747|Sphingobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, deoR family	glcR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HKD3_k127_5178962_4	925409.KI911562_gene2492	1.119e-122	406.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1INUT@117747|Sphingobacteriia	976|Bacteroidetes	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
HKD3_k127_5178962_2	1123248.KB893326_gene1423	9.707e-161	523.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1IP5G@117747|Sphingobacteriia	976|Bacteroidetes	M	OstA-like protein	lptD	-	-	-	-	-	-	-	-	-	-	-	OstA_2
HKD3_k127_5178962_11	925409.KI911562_gene2320	6.097e-43	159.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1ITXA@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HKD3_k127_5178962_12	700598.Niako_1006	1.939e-34	138.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes	976|Bacteroidetes	M	InterPro IPR011467	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD3_k127_5178962_5	700598.Niako_1007	1.856e-106	355.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1ISHE@117747|Sphingobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HKD3_k127_5178962_16	1122179.KB890425_gene3551	3.124e-16	94.0	COG2353@1|root,COG2866@1|root,COG2353@2|Bacteria,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
HKD3_k127_5178962_10	1123037.AUDE01000017_gene2496	1.328e-45	190.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NMHU@976|Bacteroidetes,1I1EF@117743|Flavobacteriia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,TIG
HKD3_k127_5178962_15	880071.Fleli_0428	3.922e-20	107.0	COG1404@1|root,COG3227@1|root,COG3291@1|root,COG4386@1|root,COG1404@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	fpp2	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,PKD,Peptidase_M43
HKD3_k127_5178962_3	313606.M23134_06773	1.34e-125	443.0	COG2911@1|root,COG3291@1|root,COG4447@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4NI13@976|Bacteroidetes,47NV6@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_5188118_9	1379270.AUXF01000007_gene963	2.817e-40	151.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD3_k127_5188118_7	661478.OP10G_4294	4.032e-45	176.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD3_k127_5188118_0	1123248.KB893317_gene4317	4.813e-205	646.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1IVPN@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HKD3_k127_5188118_8	700598.Niako_2158	5.98e-41	156.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_5188118_12	1236959.BAMT01000002_gene2015	2.199e-14	79.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,2WGT1@28216|Betaproteobacteria,2KMWZ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_5188118_11	1123248.KB893325_gene1160	1.137e-30	123.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
HKD3_k127_5188118_2	1122605.KB893625_gene2232	7.422e-115	382.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1IP1J@117747|Sphingobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
HKD3_k127_5188118_1	925409.KI911562_gene2439	5.608e-171	541.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD3_k127_5188118_4	1123248.KB893337_gene2466	1.784e-68	241.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1IYXS@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
HKD3_k127_5188118_6	1123248.KB893337_gene2465	1.15e-49	182.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,1ISBW@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
HKD3_k127_5188118_3	1267211.KI669560_gene1726	1.516e-110	363.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1IPJX@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
HKD3_k127_5188118_5	485918.Cpin_5451	4.532e-67	230.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
HKD3_k127_5188118_10	700598.Niako_2053	6.626e-40	160.0	COG1196@1|root,COG1196@2|Bacteria,4PMEM@976|Bacteroidetes	976|Bacteroidetes	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
HKD3_k127_5208314_2	925409.KI911562_gene2432	6.885e-67	244.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,1IPFV@117747|Sphingobacteriia	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
HKD3_k127_5208314_3	1123248.KB893326_gene1488	3.141e-49	178.0	COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional repressor, CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HKD3_k127_5208314_1	509635.N824_12595	1.262e-104	350.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1IV9D@117747|Sphingobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HKD3_k127_5208314_0	526227.Mesil_2803	1.099e-127	418.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
HKD3_k127_5210040_3	700598.Niako_5054	1.133e-20	95.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1IPZ7@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_5210040_0	925409.KI911562_gene2980	1.176e-172	548.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,1INRW@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
HKD3_k127_5210040_1	1121373.KB903629_gene373	7.782e-129	417.0	COG0265@1|root,COG0265@2|Bacteria,4NFAJ@976|Bacteroidetes,47N2H@768503|Cytophagia	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
HKD3_k127_5210040_2	714943.Mucpa_5102	9.902e-67	239.0	COG0156@1|root,COG0156@2|Bacteria,4NKC1@976|Bacteroidetes,1IS9B@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HKD3_k127_5245837_4	35754.JNYJ01000086_gene2294	2.188e-11	74.0	COG0793@1|root,COG0793@2|Bacteria,2I1TN@201174|Actinobacteria,4DJH1@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase family S41	nsr	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
HKD3_k127_5245837_2	1450525.JATV01000008_gene712	1.579e-28	123.0	COG1943@1|root,COG1943@2|Bacteria,4NPWC@976|Bacteroidetes,1I28P@117743|Flavobacteriia,2NW4C@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD3_k127_5245837_0	1267211.KI669560_gene1177	2.588e-314	977.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,1IRP7@117747|Sphingobacteriia	976|Bacteroidetes	V	Peptidase C39	-	-	-	ko:K20344	ko02010,ko02024,map02010,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
HKD3_k127_5245837_1	1267211.KI669560_gene1176	2.809e-89	307.0	COG0845@1|root,COG0845@2|Bacteria,4NI1E@976|Bacteroidetes,1IX1Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K20345	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
HKD3_k127_5245837_3	925409.KI911562_gene402	8.11e-15	79.0	2EQFM@1|root,33I1M@2|Bacteria,4NZD7@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD3_k127_5262968_0	686340.Metal_1478	0.0	1382.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XDKG@135618|Methylococcales	135618|Methylococcales	U	Hydrophobe Amphiphile Efflux-1 (HAE1)	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD3_k127_5262968_1	926549.KI421517_gene2934	5.55e-122	399.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,47K2C@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HKD3_k127_5357373_2	925409.KI911562_gene373	6.397e-49	175.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD3_k127_5357373_0	1267211.KI669560_gene32	6.487e-127	421.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1IRSG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD3_k127_5357373_3	700598.Niako_2074	4.165e-39	152.0	2DVQJ@1|root,32UZZ@2|Bacteria,4PGTB@976|Bacteroidetes,1IUA6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5357373_1	696747.NIES39_C05180	5.06e-72	269.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
HKD3_k127_5409479_3	1347342.BN863_30410	5.914e-21	104.0	COG0366@1|root,COG0366@2|Bacteria,4PKH4@976|Bacteroidetes,1IJ8S@117743|Flavobacteriia	976|Bacteroidetes	G	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
HKD3_k127_5409479_0	485918.Cpin_0676	9.94e-103	344.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1IQ8K@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD3_k127_5409479_2	925409.KI911562_gene1088	3.15e-31	128.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1IU3P@117747|Sphingobacteriia	976|Bacteroidetes	S	GldH lipoprotein	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
HKD3_k127_5409479_1	1123248.KB893348_gene266	3.345e-38	148.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_5441937_0	1089547.KB913014_gene4864	7.133e-183	581.0	28JP4@1|root,2Z9F6@2|Bacteria,4NDYM@976|Bacteroidetes,47NY9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5441937_1	1121887.AUDK01000023_gene3473	3.072e-106	354.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia,2NW6Q@237|Flavobacterium	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD3_k127_5441937_2	1239962.C943_03758	1.2e-55	199.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
HKD3_k127_5441937_3	1239962.C943_03759	9.914e-52	186.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_5475301_1	1173028.ANKO01000194_gene6028	1.16e-252	812.0	COG3250@1|root,COG3250@2|Bacteria,1G4FY@1117|Cyanobacteria,1HA7W@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_5475301_0	700598.Niako_2383	0.0	1106.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQT8@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_5475301_2	760192.Halhy_0224	3.681e-125	406.0	COG3970@1|root,COG3970@2|Bacteria,4NGTH@976|Bacteroidetes,1IQ0W@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3970 Fumarylacetoacetate (FAA) hydrolase family protein	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
HKD3_k127_549198_2	1123248.KB893385_gene4879	3.983e-117	386.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1IQ58@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_549198_8	700598.Niako_5711	1.662e-42	159.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1ISV5@117747|Sphingobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD3_k127_549198_3	1123248.KB893385_gene4877	1.703e-116	388.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1IPJE@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
HKD3_k127_549198_0	925409.KI911562_gene1444	8.281e-142	454.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1IPAD@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD3_k127_549198_4	1123248.KB893385_gene4876	1.842e-95	325.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1INPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
HKD3_k127_549198_5	925409.KI911562_gene1446	4.416e-81	273.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD3_k127_549198_6	938709.AUSH02000011_gene1187	3.941e-74	260.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes	976|Bacteroidetes	EG	of the drug metabolite transporter (DMT) superfamily	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_549198_9	1267211.KI669560_gene2722	7.016e-40	153.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1IY9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Large-conductance mechanosensitive channel, MscL	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HKD3_k127_549198_7	1122605.KB893628_gene4451	1.667e-58	215.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1IPAT@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
HKD3_k127_549198_1	700598.Niako_5701	1.133e-118	386.0	COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,1IPTD@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD3_k127_564328_6	391623.TERMP_01436	4.082e-09	63.0	arCOG07790@1|root,arCOG07790@2157|Archaea,2Y0S6@28890|Euryarchaeota,2437F@183968|Thermococci	183968|Thermococci	S	D-glucuronyl C5-epimerase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	C5-epim_C
HKD3_k127_564328_4	1121011.AUCB01000012_gene1576	1.073e-48	178.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia,23HFM@178469|Arenibacter	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_564328_3	641526.ADIWIN_2413	7.616e-61	215.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia	976|Bacteroidetes	S	YeeE YedE family	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_564328_5	1356852.N008_06955	3.639e-09	67.0	2E7UT@1|root,3329Q@2|Bacteria,4NUQ3@976|Bacteroidetes,47SB3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_564328_0	1267211.KI669560_gene2720	0.0	1126.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1INUN@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_564328_1	925409.KI911562_gene1461	7.686e-127	410.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
HKD3_k127_564328_2	1122605.KB893626_gene2583	1.87e-77	271.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_5706061_0	925409.KI911562_gene2902	1.196e-159	504.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1IP5T@117747|Sphingobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_5706061_1	925409.KI911562_gene2901	1.897e-121	395.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1IQ26@117747|Sphingobacteriia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HKD3_k127_5706061_3	641524.ADICYQ_4164	3.732e-10	64.0	COG3668@1|root,COG3668@2|Bacteria,4NQMN@976|Bacteroidetes	976|Bacteroidetes	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
HKD3_k127_5706061_4	1453505.JASY01000003_gene2069	1.868e-05	49.0	2EAY9@1|root,334Z9@2|Bacteria,4NV3Y@976|Bacteroidetes,1I5AJ@117743|Flavobacteriia,2NXU1@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5706061_2	1123248.KB893348_gene156	1.453e-110	361.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_5735994_1	1267211.KI669560_gene688	9.53e-73	249.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1ISJH@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD3_k127_5735994_6	700598.Niako_6218	1.384e-17	87.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HKD3_k127_5735994_5	1121377.KB906404_gene2830	6.207e-21	95.0	2ECRS@1|root,336PE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
HKD3_k127_5735994_2	925409.KI911562_gene882	5.333e-62	222.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1IS0E@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
HKD3_k127_5735994_3	1267211.KI669560_gene697	2.179e-39	151.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1ISS0@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HKD3_k127_5735994_0	1123248.KB893319_gene4072	2.515e-236	738.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IQ2Z@117747|Sphingobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD3_k127_5839809_3	929556.Solca_2958	8.482e-109	362.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQPI@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_5839809_0	700598.Niako_5048	0.0	1064.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IURB@117747|Sphingobacteriia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD3_k127_5839809_6	700598.Niako_5049	1.369e-53	192.0	COG0629@1|root,COG0629@2|Bacteria,4NVAN@976|Bacteroidetes	976|Bacteroidetes	L	single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_5839809_1	700598.Niako_5047	1.175e-210	657.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD3_k127_5839809_5	1123248.KB893326_gene1309	1.509e-63	228.0	298K1@1|root,3122S@2|Bacteria,4PGXN@976|Bacteroidetes,1IUN3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5839809_4	700598.Niako_5044	3.988e-88	304.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1IPTE@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
HKD3_k127_5839809_2	1123248.KB893370_gene5084	7.12e-180	573.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1IP4Q@117747|Sphingobacteriia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_5839809_7	531844.FIC_01949	2.483e-12	76.0	COG1345@1|root,COG4677@1|root,COG1345@2|Bacteria,COG4677@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	TIG
HKD3_k127_6048157_8	1121904.ARBP01000025_gene6110	9.159e-08	60.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6048157_1	1121904.ARBP01000025_gene6111	5.18e-234	763.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6048157_7	1121481.AUAS01000021_gene2867	1.945e-18	97.0	COG3712@1|root,COG3712@2|Bacteria,4P2D1@976|Bacteroidetes,47UR4@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_6048157_0	1089547.KB913013_gene3019	6.134e-253	790.0	COG0665@1|root,COG0665@2|Bacteria,4NFTJ@976|Bacteroidetes,47KRM@768503|Cytophagia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HKD3_k127_6048157_2	1121904.ARBP01000025_gene6111	5.844e-193	646.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6048157_5	925409.KI911562_gene1062	1.674e-43	172.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_6048157_6	925409.KI911562_gene1061	2.192e-37	148.0	COG1595@1|root,COG1595@2|Bacteria,4NRYV@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6048157_4	925409.KI911562_gene1663	9.164e-100	338.0	COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,1INM9@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
HKD3_k127_6048157_3	929562.Emtol_3600	1.301e-135	441.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47JTF@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
HKD3_k127_6058660_0	1239962.C943_03759	1.123e-246	766.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_6058660_2	1123278.KB893419_gene1222	7.125e-29	121.0	2E0CF@1|root,32VZF@2|Bacteria,4NSWX@976|Bacteroidetes,47SN1@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
HKD3_k127_6058660_1	504728.K649_00680	9.094e-73	248.0	28H95@1|root,2Z7KY@2|Bacteria,1WMI1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
HKD3_k127_6058660_3	448385.sce3974	1.033e-25	113.0	COG3506@1|root,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	yjl217W	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
HKD3_k127_6066988_7	313595.P700755_002947	2.154e-11	70.0	COG3548@1|root,COG3548@2|Bacteria,4NW8Z@976|Bacteroidetes,1I72V@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD3_k127_6066988_3	1191523.MROS_2264	8.942e-71	244.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porG	-	1.2.7.3,1.2.7.7	ko:K00177,ko:K00187	ko00020,ko00280,ko00720,ko01100,ko01120,ko01200,map00020,map00280,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197,R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
HKD3_k127_6066988_2	945713.IALB_0273	8.283e-112	369.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD3_k127_6066988_1	945713.IALB_0272	6.591e-154	493.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
HKD3_k127_6066988_6	1191523.MROS_2261	1.185e-23	104.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	vorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21,Fer4_4,Fer4_7
HKD3_k127_6066988_5	1185876.BN8_02923	3.119e-37	150.0	2C25Y@1|root,3399H@2|Bacteria,4NXDI@976|Bacteroidetes,47SDB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6066988_0	700598.Niako_5481	3.537e-169	547.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
HKD3_k127_6066988_4	1123248.KB893337_gene2560	1.93e-50	205.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,Big_3_5,ChW,He_PIG,LRR_5,Peptidase_S8,TIG
HKD3_k127_6067290_10	1123248.KB893321_gene533	5.885e-25	107.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HKD3_k127_6067290_1	485918.Cpin_2008	1.459e-156	504.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1IV9H@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_6067290_4	485918.Cpin_2010	1.095e-90	309.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1IUSP@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_6067290_3	925409.KI911562_gene1879	3.781e-92	308.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1IPVS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HKD3_k127_6067290_9	925409.KI911562_gene1880	1.483e-26	120.0	COG0457@1|root,COG0457@2|Bacteria	925409.KI911562_gene1880|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6067290_2	700598.Niako_0824	1.048e-155	514.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
HKD3_k127_6067290_0	1267211.KI669560_gene2082	2.146e-173	552.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
HKD3_k127_6067290_7	1123248.KB893314_gene3699	6.162e-46	170.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6067290_5	1086011.HJ01_02925	6.707e-89	306.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia,2NSRP@237|Flavobacterium	976|Bacteroidetes	E	aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_6067290_6	468059.AUHA01000003_gene1557	5.155e-68	234.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1IRXF@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD3_k127_6067290_8	700598.Niako_4475	4.463e-40	151.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1IPEN@117747|Sphingobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
HKD3_k127_6073195_1	489825.LYNGBM3L_39610	1.081e-94	332.0	COG1874@1|root,COG1874@2|Bacteria,1GD0C@1117|Cyanobacteria	1117|Cyanobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6073195_3	1089547.KB913013_gene1029	1.045e-08	59.0	COG5434@1|root,COG5434@2|Bacteria,4NMVX@976|Bacteroidetes,47S79@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
HKD3_k127_6073195_0	714943.Mucpa_0035	5.324e-177	571.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,1IQ13@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
HKD3_k127_6073195_2	1089547.KB913013_gene1029	1.67e-77	272.0	COG5434@1|root,COG5434@2|Bacteria,4NMVX@976|Bacteroidetes,47S79@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
HKD3_k127_6075515_0	509635.N824_10110	3.551e-210	658.0	COG4948@1|root,COG4948@2|Bacteria,4NGZF@976|Bacteroidetes,1IQ82@117747|Sphingobacteriia	976|Bacteroidetes	M	mandelate racemase	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_6075515_1	925409.KI911562_gene2734	8.107e-169	540.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
HKD3_k127_6075515_2	509635.N824_10095	3.172e-100	332.0	COG1028@1|root,COG1028@2|Bacteria,4NHUF@976|Bacteroidetes,1IP0M@117747|Sphingobacteriia	976|Bacteroidetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD3_k127_6100456_0	1123248.KB893386_gene1940	5.815e-302	947.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IP7J@117747|Sphingobacteriia	976|Bacteroidetes	P	SPTR ATPase, P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD3_k127_6100456_1	700598.Niako_6295	4.036e-175	559.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IWYY@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
HKD3_k127_6100456_11	314285.KT71_05457	2.402e-17	90.0	2DVAY@1|root,33V2X@2|Bacteria,1QRB5@1224|Proteobacteria,1SNCZ@1236|Gammaproteobacteria,1JA07@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6100456_5	929703.KE386491_gene1952	1.779e-78	270.0	COG4221@1|root,COG4221@2|Bacteria,4NHEQ@976|Bacteroidetes,47M62@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_6100456_3	1313421.JHBV01000010_gene4163	2.54e-83	289.0	COG2267@1|root,COG2267@2|Bacteria,4NK38@976|Bacteroidetes	976|Bacteroidetes	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
HKD3_k127_6100456_2	700598.Niako_6421	4.211e-158	503.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,1IR2B@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
HKD3_k127_6100456_10	1123248.KB893348_gene123	4.143e-18	85.0	2ACEV@1|root,3120D@2|Bacteria,4PGV7@976|Bacteroidetes,1IUFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6100456_8	1168289.AJKI01000014_gene2052	4.883e-44	166.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,2FTXH@200643|Bacteroidia,3XKUU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_6100456_6	1267211.KI669560_gene2099	4.947e-78	270.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HKD3_k127_6100456_9	1131812.JQMS01000001_gene765	1.389e-21	99.0	2BK9M@1|root,32EPT@2|Bacteria,4NQGA@976|Bacteroidetes,1I2SP@117743|Flavobacteriia,2NWJ8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6100456_12	1137281.D778_02225	1.31e-10	68.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6100456_4	925409.KI911562_gene762	4.775e-79	265.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HKD3_k127_6101388_2	700598.Niako_5176	0.0	1041.0	COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,SprB
HKD3_k127_6101388_22	1267211.KI669560_gene1764	1.372e-35	146.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
HKD3_k127_6101388_25	1267211.KI669560_gene1763	4.418e-07	59.0	COG5608@1|root,COG5608@2|Bacteria,4NVQ5@976|Bacteroidetes,1IZWS@117747|Sphingobacteriia	976|Bacteroidetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
HKD3_k127_6101388_24	700598.Niako_1172	2.672e-22	100.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA,TonB_dep_Rec
HKD3_k127_6101388_12	925409.KI911562_gene2200	4.065e-104	341.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1IPI8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
HKD3_k127_6101388_19	700598.Niako_1170	3.216e-47	177.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1ITRK@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_6101388_18	700598.Niako_1169	5.329e-56	198.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1IT04@117747|Sphingobacteriia	976|Bacteroidetes	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
HKD3_k127_6101388_15	1123248.KB893321_gene528	3.488e-73	249.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1ISUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD3_k127_6101388_6	1267211.KI669560_gene1757	1.469e-169	535.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD3_k127_6101388_16	700598.Niako_0369	1.39e-66	242.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1IT79@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD3_k127_6101388_10	925409.KI911562_gene2194	1.028e-150	484.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1IQSA@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
HKD3_k127_6101388_13	700598.Niako_2567	1.72e-98	333.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HKD3_k127_6101388_0	700598.Niako_2568	0.0	1384.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IP63@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
HKD3_k127_6101388_17	1123248.KB893386_gene1810	3.49e-57	219.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1INTW@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD3_k127_6101388_14	700598.Niako_2570	3.232e-74	252.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1IRVT@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HKD3_k127_6101388_9	925409.KI911562_gene2706	3.179e-153	501.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1IP68@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HKD3_k127_6101388_3	1267211.KI669560_gene1470	1.288e-236	738.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1IP0Q@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
HKD3_k127_6101388_7	1123248.KB893340_gene2670	5.9e-168	537.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1INY0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_6101388_11	471854.Dfer_4564	3.302e-116	387.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,47K31@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
HKD3_k127_6101388_23	1236514.BAKL01000087_gene4907	3.175e-30	126.0	COG0791@1|root,COG0791@2|Bacteria,4NQSZ@976|Bacteroidetes,2FS8Y@200643|Bacteroidia,4APDR@815|Bacteroidaceae	976|Bacteroidetes	M	NlpC P60 family	mepS	-	3.4.17.13	ko:K13694	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HKD3_k127_6101388_1	1123248.KB893317_gene4278	0.0	1260.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1IP7W@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD3_k127_6101388_20	234267.Acid_0675	2.692e-43	162.0	2EB0S@1|root,3351M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6101388_21	1410608.JNKX01000030_gene161	1.091e-36	142.0	COG3743@1|root,COG3743@2|Bacteria,4NPY9@976|Bacteroidetes,2G3BJ@200643|Bacteroidia,4AS0F@815|Bacteroidaceae	976|Bacteroidetes	L	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
HKD3_k127_6101388_8	700598.Niako_5241	8.556e-161	516.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IQ0I@117747|Sphingobacteriia	976|Bacteroidetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
HKD3_k127_6101388_4	1267211.KI669560_gene472	1.993e-218	694.0	COG0644@1|root,COG0644@2|Bacteria,4PMBP@976|Bacteroidetes,1IQ1V@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HKD3_k127_6101388_5	1166018.FAES_5035	3.188e-172	559.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47KT8@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD3_k127_6104198_0	925409.KI911562_gene1379	0.0	1405.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IUT7@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_6104198_3	700598.Niako_2088	1.721e-44	169.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1IS81@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_6104198_1	700598.Niako_2087	5.14e-157	510.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
HKD3_k127_6104198_2	1123248.KB893337_gene2489	2.108e-48	177.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1IQ45@117747|Sphingobacteriia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
HKD3_k127_6109391_9	1239962.C943_01492	3.701e-61	217.0	2CCNY@1|root,2Z877@2|Bacteria,4NR3D@976|Bacteroidetes	976|Bacteroidetes	E	CpeT/CpcT family (DUF1001)	-	-	-	-	-	-	-	-	-	-	-	-	CpeT
HKD3_k127_6109391_8	700598.Niako_6287	1.269e-67	233.0	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,1IT46@117747|Sphingobacteriia	976|Bacteroidetes	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HKD3_k127_6109391_5	485918.Cpin_0825	3.209e-71	248.0	COG1136@1|root,COG1136@2|Bacteria,4NN5Z@976|Bacteroidetes,1IXVG@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_6109391_3	485918.Cpin_0826	3.789e-103	349.0	COG0577@1|root,COG0577@2|Bacteria,4NGDV@976|Bacteroidetes,1IXUG@117747|Sphingobacteriia	976|Bacteroidetes	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6109391_1	925409.KI911562_gene630	1.614e-191	608.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1IR5V@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD3_k127_6109391_11	700598.Niako_6109	6.275e-47	176.0	COG1595@1|root,COG1595@2|Bacteria,4NR0P@976|Bacteroidetes,1J0AP@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6109391_7	700598.Niako_4405	2.057e-69	249.0	COG3712@1|root,COG3712@2|Bacteria,4NM0I@976|Bacteroidetes	976|Bacteroidetes	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD3_k127_6109391_0	1267211.KI669560_gene1247	0.0	1219.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IP84@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6109391_2	1267211.KI669560_gene1248	5.233e-167	539.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1IPKS@117747|Sphingobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6109391_4	531844.FIC_01525	5.325e-79	273.0	28MFR@1|root,2ZAT4@2|Bacteria,4NM07@976|Bacteroidetes	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
HKD3_k127_6109983_2	1492737.FEM08_10500	1.446e-109	358.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1HX4W@117743|Flavobacteriia,2NTN8@237|Flavobacterium	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
HKD3_k127_6109983_0	925409.KI911562_gene1640	7.032e-133	428.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,1IP7R@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	uxuB	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HKD3_k127_6109983_1	1122605.KB893644_gene1504	2.108e-117	383.0	COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,1IP6Y@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
HKD3_k127_6109983_3	1089547.KB913013_gene1179	5.882e-102	345.0	COG4677@1|root,COG4677@2|Bacteria,4NF12@976|Bacteroidetes,47MK7@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF4861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_88
HKD3_k127_6116593_6	925409.KI911562_gene3034	9.337e-110	357.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HKD3_k127_6116593_13	485918.Cpin_1614	9.485e-54	190.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1ISQN@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HKD3_k127_6116593_1	929562.Emtol_1426	0.0	1301.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_6116593_19	1122176.KB903532_gene2638	1.75e-33	138.0	2CE7Q@1|root,32RZA@2|Bacteria,4NSYK@976|Bacteroidetes,1IZ79@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6116593_0	1123278.KB893488_gene6076	0.0	1364.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_6116593_25	1185876.BN8_04256	5.353e-12	78.0	COG0296@1|root,COG1680@1|root,COG0296@2|Bacteria,COG1680@2|Bacteria,4NG6Z@976|Bacteroidetes,47PR8@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Beta-lactamase
HKD3_k127_6116593_18	1121931.AUHG01000020_gene3175	1.793e-37	158.0	COG0296@1|root,COG0296@2|Bacteria,4NJ7Z@976|Bacteroidetes,1HZ6E@117743|Flavobacteriia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
HKD3_k127_6116593_20	319236.JCM19294_2162	3.527e-30	132.0	2DBKE@1|root,2Z9SW@2|Bacteria,4NRWN@976|Bacteroidetes,1I012@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
HKD3_k127_6116593_4	925409.KI911562_gene2249	2.555e-240	745.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,1INSE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_6116593_14	1408813.AYMG01000011_gene834	1.032e-53	198.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_6116593_22	1089547.KB913013_gene2813	4.05e-26	112.0	COG4538@1|root,COG4538@2|Bacteria,4NX66@976|Bacteroidetes,47XBQ@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD3_k127_6116593_12	485918.Cpin_5838	1.301e-54	196.0	COG0457@1|root,COG0457@2|Bacteria,4PN8J@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD3_k127_6116593_5	592029.DDD_2769	1.403e-135	443.0	COG1858@1|root,COG1858@2|Bacteria,4PIQQ@976|Bacteroidetes,1ICB6@117743|Flavobacteriia,3HM6E@363408|Nonlabens	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
HKD3_k127_6116593_10	391596.PBAL39_25600	2.024e-70	258.0	COG3193@1|root,COG3193@2|Bacteria,4PMGZ@976|Bacteroidetes	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_6116593_2	391596.PBAL39_25605	7.979e-254	816.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6116593_15	247490.KSU1_C0449	6.224e-47	191.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
HKD3_k127_6116593_7	925409.KI911562_gene2824	4.45e-102	336.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1INR8@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HKD3_k127_6116593_23	925409.KI911562_gene2825	1.402e-23	100.0	COG0690@1|root,COG0690@2|Bacteria,4PGJJ@976|Bacteroidetes,1ITUV@117747|Sphingobacteriia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HKD3_k127_6116593_3	1123248.KB893381_gene1066	2.449e-242	751.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1IPDP@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HKD3_k127_6116593_27	1236518.BAKP01000026_gene1675	5.98e-05	46.0	2DD50@1|root,2ZGIJ@2|Bacteria,4P8A2@976|Bacteroidetes,2FZIU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6116593_17	925409.KI911562_gene2828	8.257e-38	144.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1ITNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
HKD3_k127_6116593_8	1123248.KB893314_gene3629	5.381e-98	329.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1IP2Y@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_6116593_21	925409.KI911562_gene2830	5.867e-27	110.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1IU0K@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HKD3_k127_6116593_16	1408473.JHXO01000013_gene564	7.054e-39	151.0	COG3610@1|root,COG3610@2|Bacteria,4NU0J@976|Bacteroidetes,2FPKT@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
HKD3_k127_6116593_11	1239962.C943_04259	3.347e-62	224.0	COG2966@1|root,COG2966@2|Bacteria,4NIU3@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG2966 conserved	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
HKD3_k127_6116593_9	700598.Niako_4947	6.778e-84	282.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1IPZJ@117747|Sphingobacteriia	976|Bacteroidetes	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HKD3_k127_6116593_28	925409.KI911562_gene2616	0.0005081	44.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1IP9Q@117747|Sphingobacteriia	976|Bacteroidetes	H	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HKD3_k127_6126857_9	1121904.ARBP01000003_gene6380	8.16e-21	97.0	298PG@1|root,2ZVTY@2|Bacteria,4NP4F@976|Bacteroidetes,47PR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6126857_5	1487953.JMKF01000045_gene2916	4.465e-57	211.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria,1H8PU@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM UbiA prenyltransferase	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
HKD3_k127_6126857_1	1267211.KI669560_gene1308	1.143e-156	502.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_6126857_6	1267211.KI669560_gene1731	4.627e-55	197.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes	976|Bacteroidetes	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HKD3_k127_6126857_4	1123248.KB893314_gene3380	5.289e-72	250.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1IRYX@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HKD3_k127_6126857_7	1123248.KB893314_gene3382	3.259e-43	165.0	COG0824@1|root,COG0824@2|Bacteria,4NT54@976|Bacteroidetes,1J0GC@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
HKD3_k127_6126857_3	700598.Niako_4702	2.788e-89	301.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
HKD3_k127_6126857_2	925409.KI911562_gene12	9.896e-146	464.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IPYS@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM (2R)-phospho-3-sulfolactate synthase ComA	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
HKD3_k127_6126857_0	925409.KI911562_gene13	1.737e-191	608.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
HKD3_k127_6126857_10	700598.Niako_4706	7.661e-08	55.0	2DS3S@1|root,33EDT@2|Bacteria,4NY8U@976|Bacteroidetes,1IUQ6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6139803_1	929713.NIASO_06925	8.119e-223	694.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1IPEN@117747|Sphingobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
HKD3_k127_6139803_2	760192.Halhy_4374	8.793e-200	631.0	COG0673@1|root,COG0673@2|Bacteria,4NIF1@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_6139803_0	1123248.KB893381_gene1048	7.74e-315	990.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,1IQHQ@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6139803_10	1041930.Mtc_0051	1.104e-23	101.0	COG1476@1|root,arCOG01864@2157|Archaea,2Y089@28890|Euryarchaeota,2NA1I@224756|Methanomicrobia	224756|Methanomicrobia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD3_k127_6139803_9	925409.KI911562_gene1886	1.085e-35	139.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1IT95@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HKD3_k127_6139803_11	983544.Lacal_0389	4.192e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HKD3_k127_6139803_7	925409.KI911562_gene1887	1.237e-63	219.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HKD3_k127_6139803_6	1267211.KI669560_gene2076	1.314e-64	222.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1ISSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HKD3_k127_6139803_4	485918.Cpin_1641	2.191e-109	355.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD3_k127_6139803_3	700598.Niako_4456	1.313e-181	571.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1IQ3D@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HKD3_k127_6139803_5	1267211.KI669560_gene2073	1.825e-67	233.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1IRYB@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HKD3_k127_6139803_8	1270196.JCKI01000002_gene298	7.493e-50	181.0	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,1ISR5@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
HKD3_k127_6151852_1	700598.Niako_2624	1.544e-155	493.0	COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
HKD3_k127_6151852_0	925409.KI911562_gene917	8.623e-208	655.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,1IQZG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_6151852_2	700598.Niako_6255	1.842e-09	60.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,1INUU@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydroxypyruvate isomerase	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
HKD3_k127_6175114_3	1454007.JAUG01000039_gene4260	4.144e-24	102.0	COG2755@1|root,COG2755@2|Bacteria,4NGSE@976|Bacteroidetes,1IPR1@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_6175114_0	929713.NIASO_04995	1.572e-282	880.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1IQRQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
HKD3_k127_6175114_1	929713.NIASO_04985	9.555e-253	793.0	COG5434@1|root,COG5434@2|Bacteria,4NDWX@976|Bacteroidetes	976|Bacteroidetes	M	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_6175114_2	1288963.ADIS_1506	7.952e-47	177.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6196823_0	1189612.A33Q_0629	0.0	1523.0	COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
HKD3_k127_6196823_1	1189612.A33Q_0628	5.585e-103	347.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipoxygenase
HKD3_k127_6234609_1	925409.KI911562_gene2010	8.598e-84	291.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1IP87@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD3_k127_6234609_0	929713.NIASO_05365	2.517e-90	308.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1IV9F@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HKD3_k127_6234609_2	485918.Cpin_4705	1.813e-80	277.0	COG1216@1|root,COG1216@2|Bacteria,4NQSJ@976|Bacteroidetes,1J0NH@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_6246769_17	700598.Niako_6658	5.416e-100	332.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1INYY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
HKD3_k127_6246769_14	1267211.KI669560_gene370	5.569e-102	336.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1IQ7Q@117747|Sphingobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD3_k127_6246769_9	760192.Halhy_6846	5e-127	413.0	COG3329@1|root,COG3329@2|Bacteria,4NIR4@976|Bacteroidetes,1IW46@117747|Sphingobacteriia	976|Bacteroidetes	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
HKD3_k127_6246769_13	700598.Niako_6078	4.963e-103	342.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1IRSU@117747|Sphingobacteriia	976|Bacteroidetes	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD3_k127_6246769_0	925409.KI911562_gene724	0.0	1059.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1IV6E@117747|Sphingobacteriia	976|Bacteroidetes	CI	MaoC like domain	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
HKD3_k127_6246769_33	700598.Niako_4444	1.511e-14	83.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_6246769_19	925409.KI911562_gene749	1.398e-84	284.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISB0@117747|Sphingobacteriia	976|Bacteroidetes	O	methionine sulfoxide reductase	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HKD3_k127_6246769_21	1267211.KI669560_gene364	6.68e-74	253.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
HKD3_k127_6246769_31	1121896.JMLU01000009_gene1605	8.372e-25	108.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1I09P@117743|Flavobacteriia,2NVJN@237|Flavobacterium	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD3_k127_6246769_16	929556.Solca_1229	1.627e-100	341.0	COG3187@1|root,COG3187@2|Bacteria,4NEY0@976|Bacteroidetes,1IQ5Y@117747|Sphingobacteriia	976|Bacteroidetes	O	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3,META
HKD3_k127_6246769_32	479433.Caci_1262	2.087e-21	97.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817,MFS_1
HKD3_k127_6246769_1	700598.Niako_5795	3.51e-254	793.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
HKD3_k127_6246769_37	984262.SGRA_2566	1.598e-07	52.0	2DTGS@1|root,33K9M@2|Bacteria,4NYMF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6246769_23	700598.Niako_5793	2.135e-58	214.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HKD3_k127_6246769_25	1123248.KB893386_gene1839	4.026e-47	174.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1ISXQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_6246769_11	925409.KI911562_gene1102	5.571e-120	397.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1IPZD@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
HKD3_k127_6246769_22	1123248.KB893348_gene321	3.54e-68	242.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ISJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_6246769_7	1123248.KB893348_gene320	1.139e-161	520.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1IVGY@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_6246769_18	1123248.KB893348_gene82	2.022e-86	291.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6246769_15	700598.Niako_5253	1.06e-100	336.0	COG1723@1|root,COG1723@2|Bacteria,4NFED@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
HKD3_k127_6246769_5	925409.KI911562_gene387	2.601e-189	604.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_6246769_30	742767.HMPREF9456_02326	2.023e-29	123.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,2FPT2@200643|Bacteroidia,22YQF@171551|Porphyromonadaceae	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD3_k127_6246769_38	1239962.C943_03767	4.63e-06	57.0	2FG5W@1|root,3482C@2|Bacteria,4P5PR@976|Bacteroidetes,47VV9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6246769_6	1267211.KI669560_gene708	5.664e-179	568.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HKD3_k127_6246769_29	700598.Niako_6243	3.076e-38	148.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1IT21@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD3_k127_6246769_3	925409.KI911562_gene454	3.147e-197	621.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
HKD3_k127_6246769_20	1123248.KB893331_gene3779	6.644e-76	264.0	COG3757@1|root,COG3757@2|Bacteria,4NKHF@976|Bacteroidetes,1ISMY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl hydrolases family 25	acm	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
HKD3_k127_6246769_36	326297.Sama_1061	1.128e-08	66.0	COG2849@1|root,COG2849@2|Bacteria,1NIRM@1224|Proteobacteria,1SIRG@1236|Gammaproteobacteria,2Q9S5@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM MORN variant repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD3_k127_6246769_4	925409.KI911562_gene436	8.111e-197	620.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HKD3_k127_6246769_27	1123248.KB893386_gene1827	2.071e-43	162.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1ITN4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
HKD3_k127_6246769_28	1267211.KI669560_gene117	1.278e-40	155.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ITMD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_6246769_26	1123248.KB893386_gene1826	7.306e-45	165.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ITMD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_6246769_12	925409.KI911562_gene434	1.465e-104	344.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IPNP@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
HKD3_k127_6246769_8	925409.KI911562_gene782	9.026e-134	436.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,1IRWP@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD3_k127_6246769_24	1123248.KB893331_gene3765	6.13e-56	199.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1ISSQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6246769_35	485918.Cpin_6284	1.056e-13	76.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
HKD3_k127_6246769_10	700598.Niako_6593	1.033e-124	405.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD3_k127_6246769_2	700598.Niako_6594	7.236e-216	683.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HKD3_k127_6254183_0	1123248.KB893331_gene3749	5.461e-135	435.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1IPI0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_6254183_1	1123248.KB893348_gene278	1.117e-104	353.0	COG0860@1|root,COG0860@2|Bacteria,4NH6Q@976|Bacteroidetes	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
HKD3_k127_6254183_2	1121481.AUAS01000001_gene4757	6.642e-72	244.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47KCX@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD3_k127_6274915_1	700598.Niako_5065	7.284e-200	629.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1INX4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HKD3_k127_6274915_6	980584.AFPB01000087_gene205	1.986e-39	156.0	COG3595@1|root,COG3595@2|Bacteria,4PPCU@976|Bacteroidetes,1IKIF@117743|Flavobacteriia,4079E@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_6274915_4	760192.Halhy_2333	1.245e-122	407.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1IPF0@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08156	-	-	-	-	ko00000,ko02000	2.A.1.2.14	-	-	MFS_1,Sugar_tr
HKD3_k127_6274915_3	714943.Mucpa_4213	2.67e-137	443.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD3_k127_6274915_2	313606.M23134_06918	1.624e-153	495.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47JWT@768503|Cytophagia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
HKD3_k127_6274915_0	700598.Niako_2188	0.0	1091.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6274915_5	925409.KI911562_gene2086	5.679e-111	363.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_6279778_2	1123248.KB893348_gene232	4.216e-90	299.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_6279778_7	1237149.C900_03601	9.634e-13	75.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
HKD3_k127_6279778_3	929713.NIASO_05035	2.227e-72	249.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1IVY0@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_6279778_0	929713.NIASO_05040	4.227e-105	366.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1INUH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
HKD3_k127_6279778_1	1239962.C943_00421	7.521e-98	338.0	2FGQ8@1|root,348JR@2|Bacteria,4P6IS@976|Bacteroidetes,47VVX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6279778_5	471854.Dfer_3029	1.271e-20	108.0	COG3209@1|root,COG3209@2|Bacteria,4PKW4@976|Bacteroidetes,47Y7S@768503|Cytophagia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_6279778_4	471854.Dfer_3346	7.361e-36	157.0	COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,47Y7S@768503|Cytophagia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_6279778_6	1268622.AVS7_04161	8.592e-15	82.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria	1224|Proteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD3_k127_6293883_1	1123234.AUKI01000019_gene467	7.945e-96	327.0	28I9R@1|root,2Z8CE@2|Bacteria,4NNRK@976|Bacteroidetes,1I2Q7@117743|Flavobacteriia	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
HKD3_k127_6293883_2	700598.Niako_4351	1.599e-32	136.0	COG0484@1|root,COG0484@2|Bacteria,4P77W@976|Bacteroidetes	976|Bacteroidetes	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
HKD3_k127_6293883_0	929562.Emtol_0801	4.614e-143	460.0	COG1816@1|root,COG1816@2|Bacteria,4NJ8S@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
HKD3_k127_6299977_3	471870.BACINT_02747	8.725e-30	121.0	COG4225@1|root,COG4225@2|Bacteria,4NDYS@976|Bacteroidetes,2FM61@200643|Bacteroidia,4ANMT@815|Bacteroidaceae	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
HKD3_k127_6299977_2	1268240.ATFI01000001_gene2728	9.424e-84	297.0	COG5434@1|root,COG5434@2|Bacteria,4NICS@976|Bacteroidetes,2FMGC@200643|Bacteroidia,4APJS@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
HKD3_k127_6299977_4	118163.Ple7327_1940	8.311e-24	117.0	28N1B@1|root,2ZB7I@2|Bacteria,1G011@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6299977_1	1121904.ARBP01000025_gene6099	3.398e-103	354.0	COG5434@1|root,COG5434@2|Bacteria,4NICS@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
HKD3_k127_6299977_0	1121904.ARBP01000025_gene6118	3.877e-231	724.0	COG1874@1|root,COG1874@2|Bacteria,4NK6M@976|Bacteroidetes,47MV4@768503|Cytophagia	976|Bacteroidetes	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42M
HKD3_k127_6302491_0	700598.Niako_5523	4.209e-194	620.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_6302491_2	930169.B5T_01687	9.049e-12	75.0	COG3126@1|root,COG3650@1|root,COG3126@2|Bacteria,COG3650@2|Bacteria,1N8AF@1224|Proteobacteria,1SCM7@1236|Gammaproteobacteria,1XS8E@135619|Oceanospirillales	135619|Oceanospirillales	S	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	YscW
HKD3_k127_6302491_1	362418.IW19_22345	2.161e-61	217.0	2BVY1@1|root,32QYH@2|Bacteria,4NR2M@976|Bacteroidetes,1I3HA@117743|Flavobacteriia,2NX15@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6302491_3	388413.ALPR1_21028	2.068e-11	67.0	28MAS@1|root,2ZAPE@2|Bacteria,4NJ31@976|Bacteroidetes,47TP8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
HKD3_k127_6307489_1	929713.NIASO_12990	7.403e-167	531.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1IP3N@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
HKD3_k127_6307489_6	700598.Niako_0505	5.914e-54	218.0	COG4447@1|root,COG5492@1|root,COG4447@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,PIG-L,VCBS,WxL
HKD3_k127_6307489_7	700598.Niako_1050	4.448e-41	176.0	COG1520@1|root,COG4935@1|root,COG1520@2|Bacteria,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes,1IYMI@117747|Sphingobacteriia	976|Bacteroidetes	O	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6307489_11	1127692.HMPREF9075_01384	1.997e-06	58.0	29XRT@1|root,30JHI@2|Bacteria,4PNGU@976|Bacteroidetes,1IK4Y@117743|Flavobacteriia,1ERYM@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6307489_8	1123248.KB893316_gene4597	2.183e-37	149.0	28ME7@1|root,2ZARX@2|Bacteria,4P47D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_6307489_4	1189612.A33Q_3569	1.414e-106	351.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD3_k127_6307489_5	1123248.KB893385_gene4735	5.969e-103	346.0	COG1835@1|root,COG1835@2|Bacteria,4P0FC@976|Bacteroidetes,1IYEI@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD3_k127_6307489_0	1123248.KB893385_gene4734	1.131e-296	942.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD3_k127_6307489_3	1123248.KB893316_gene4688	1.9e-114	376.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD3_k127_6307489_2	1122605.KB893626_gene2373	1.507e-120	392.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1INZJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HKD3_k127_6307489_9	1123277.KB893206_gene3485	1.799e-29	121.0	COG0454@1|root,COG0456@2|Bacteria,4NQSN@976|Bacteroidetes,47Q25@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_6308905_0	929703.KE386491_gene3058	2.716e-201	648.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47K0G@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_6308905_1	1123248.KB893348_gene81	2.682e-87	293.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1IQ2V@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
HKD3_k127_6308905_3	925409.KI911562_gene1338	9.389e-07	61.0	COG2373@1|root,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,1IQ4C@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Plug
HKD3_k127_6308905_2	1235803.C825_01264	7.497e-10	71.0	COG3307@1|root,COG3307@2|Bacteria,4NJ9U@976|Bacteroidetes,2FMEI@200643|Bacteroidia,22XAU@171551|Porphyromonadaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HKD3_k127_6315997_3	1185876.BN8_00994	2.629e-275	873.0	COG1629@1|root,COG4771@2|Bacteria,4PKQZ@976|Bacteroidetes,47TE1@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6315997_10	1185876.BN8_00995	4.16e-147	483.0	COG0521@1|root,COG0521@2|Bacteria,4P0RA@976|Bacteroidetes,47TUI@768503|Cytophagia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
HKD3_k127_6315997_17	485918.Cpin_1895	2.958e-27	119.0	COG0526@1|root,COG0526@2|Bacteria,4NUZ2@976|Bacteroidetes,1IU3I@117747|Sphingobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_6315997_9	1408813.AYMG01000028_gene2546	2.701e-159	513.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
HKD3_k127_6315997_0	509635.N824_15235	0.0	1247.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_6315997_11	1434325.AZQN01000003_gene2177	1.889e-139	456.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47JAV@768503|Cytophagia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD3_k127_6315997_8	1089547.KB913013_gene3224	1.026e-207	657.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KFX@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
HKD3_k127_6315997_4	760192.Halhy_3732	7.334e-265	839.0	COG1506@1|root,COG1506@2|Bacteria,4NGAW@976|Bacteroidetes,1IPPD@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Esterase_phd,Peptidase_S9
HKD3_k127_6315997_6	313603.FB2170_01387	1.117e-220	706.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,1HWKP@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
HKD3_k127_6315997_2	929556.Solca_0978	3.895e-320	998.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_6315997_5	760192.Halhy_3337	7.084e-246	774.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1INSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HKD3_k127_6315997_14	1267211.KI669560_gene2470	3.782e-79	269.0	COG0637@1|root,COG0637@2|Bacteria,4NID6@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
HKD3_k127_6315997_12	1267211.KI669560_gene2469	2.065e-114	373.0	COG0204@1|root,COG0204@2|Bacteria,4NG70@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_6315997_15	925409.KI911562_gene1896	3.619e-51	189.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1IRU4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
HKD3_k127_6315997_13	1270196.JCKI01000007_gene2460	2.29e-85	298.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_6315997_1	700598.Niako_2627	0.0	1150.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1IPW9@117747|Sphingobacteriia	976|Bacteroidetes	J	elongation factor G domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_6315997_16	1144313.PMI10_00992	2.345e-27	119.0	2CJ7C@1|root,32ZYU@2|Bacteria,4NUT6@976|Bacteroidetes,1I538@117743|Flavobacteriia,2NV0V@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6315997_19	700598.Niako_3302	9.004e-05	55.0	COG1520@1|root,COG1520@2|Bacteria	700598.Niako_3302|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6315997_7	700598.Niako_1583	1.749e-216	677.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IP5F@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_6349069_0	485918.Cpin_0749	0.0	1003.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1INTV@117747|Sphingobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD3_k127_6349069_2	1121904.ARBP01000001_gene5557	1.743e-56	205.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,47QAB@768503|Cytophagia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD3_k127_6349069_1	925409.KI911562_gene2835	2.745e-297	916.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1IR48@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD3_k127_6349069_3	1453505.JASY01000035_gene3832	8.787e-13	74.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
HKD3_k127_6359958_0	1267211.KI669560_gene348	4.959e-178	565.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVNR@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD3_k127_6359958_4	1121912.AUHD01000003_gene3018	1.282e-17	91.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,1I22Y@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_6359958_1	1121373.KB903664_gene2651	9.178e-154	513.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6359958_2	925409.KI911562_gene2497	1.189e-52	190.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1IU44@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6359958_3	1267211.KI669560_gene519	5.674e-34	131.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1IR43@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_6384764_7	1123248.KB893314_gene3555	4.23e-89	305.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6384764_6	929713.NIASO_09040	8.238e-100	342.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,1IPMP@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
HKD3_k127_6384764_8	1122605.KB893637_gene3157	1.663e-75	258.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IRJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
HKD3_k127_6384764_5	1123248.KB893317_gene4285	7.798e-130	422.0	COG2605@1|root,COG2605@2|Bacteria,4NHEN@976|Bacteroidetes,1IU21@117747|Sphingobacteriia	976|Bacteroidetes	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_6384764_4	1267211.KI669560_gene1547	1.932e-172	546.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1IV0I@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_6384764_12	925409.KI911562_gene2109	9.621e-47	173.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
HKD3_k127_6384764_1	1121405.dsmv_1538	0.0	1082.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,2MJ0S@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HKD3_k127_6384764_2	338966.Ppro_0419	3.408e-311	966.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,43U1C@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD3_k127_6384764_9	1267211.KI669560_gene1983	4.46e-61	220.0	COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,1IR2J@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_6384764_10	468059.AUHA01000003_gene1730	8.299e-57	207.0	COG3685@1|root,COG3685@2|Bacteria,4P08F@976|Bacteroidetes,1IV02@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
HKD3_k127_6384764_3	1123248.KB893314_gene3651	3.296e-242	771.0	COG3525@1|root,COG3537@1|root,COG3525@2|Bacteria,COG3537@2|Bacteria,4NE08@976|Bacteroidetes,1IQ32@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_6384764_14	694427.Palpr_2491	2.509e-21	107.0	COG0457@1|root,COG0457@2|Bacteria,4PH90@976|Bacteroidetes,2FT4B@200643|Bacteroidia,22Z4R@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6384764_0	1267211.KI669560_gene1549	0.0	1094.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IQAC@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
HKD3_k127_6384764_11	925409.KI911562_gene2111	1.019e-54	198.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,1ISFV@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
HKD3_k127_6402158_9	1250232.JQNJ01000001_gene1674	1.431e-36	142.0	COG2514@1|root,COG2514@2|Bacteria,4NMJC@976|Bacteroidetes,1I2B2@117743|Flavobacteriia	976|Bacteroidetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HKD3_k127_6402158_5	1267211.KI669560_gene563	7.528e-109	355.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1IQ4T@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
HKD3_k127_6402158_11	443143.GM18_2042	8.765e-18	94.0	COG0671@1|root,COG0671@2|Bacteria,1QUKE@1224|Proteobacteria,42XAW@68525|delta/epsilon subdivisions,2WT5A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_6402158_2	700598.Niako_6515	9.061e-153	487.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1IRY2@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
HKD3_k127_6402158_8	1267211.KI669560_gene724	1.932e-78	267.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1IQWM@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
HKD3_k127_6402158_7	1267211.KI669560_gene725	8.723e-81	273.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1IP7Z@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD3_k127_6402158_3	925409.KI911562_gene1053	9.003e-138	447.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1IQDH@117747|Sphingobacteriia	976|Bacteroidetes	O	protein required for cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
HKD3_k127_6402158_1	925409.KI911562_gene1054	1.429e-231	739.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,1IWMA@117747|Sphingobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD3_k127_6402158_6	1267211.KI669560_gene729	2.482e-95	321.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1IQ8Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
HKD3_k127_6402158_4	700598.Niako_6021	6.139e-116	379.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_6402158_10	1305737.JAFX01000001_gene1585	2.43e-20	98.0	COG3637@1|root,COG3637@2|Bacteria,4NUVV@976|Bacteroidetes,47WY7@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6402158_0	1267211.KI669560_gene173	0.0	1386.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1J0KU@117747|Sphingobacteriia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
HKD3_k127_6421244_2	925409.KI911562_gene1675	9.988e-43	166.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,1ITFE@117747|Sphingobacteriia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD3_k127_6421244_0	1089547.KB913013_gene4138	1.049e-156	505.0	COG0513@1|root,COG0513@2|Bacteria,4NHCA@976|Bacteroidetes,47MGW@768503|Cytophagia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HKD3_k127_6421244_1	1239962.C943_04272	2.019e-59	213.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,47QS4@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD3_k127_6423978_9	485918.Cpin_4984	1.395e-33	136.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1ITJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6423978_2	925409.KI911562_gene1031	1.235e-92	311.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1ISBF@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HKD3_k127_6423978_10	700598.Niako_6485	8.682e-22	98.0	2E5CT@1|root,3304V@2|Bacteria,4NUT8@976|Bacteroidetes,1IUKX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6423978_0	700598.Niako_0547	0.0	1023.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IR1H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD3_k127_6423978_6	1123277.KB893195_gene5660	3.07e-65	229.0	COG2080@1|root,COG2080@2|Bacteria,4NMVV@976|Bacteroidetes,47Q3P@768503|Cytophagia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD3_k127_6423978_7	1089547.KB913013_gene3599	3.716e-44	163.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
HKD3_k127_6423978_3	1267211.KI669560_gene118	1.964e-81	276.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ITGM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
HKD3_k127_6423978_4	700598.Niako_6480	1.292e-76	267.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD3_k127_6423978_8	1122605.KB893626_gene2526	2.042e-34	137.0	COG5605@1|root,COG5605@2|Bacteria,4PGS2@976|Bacteroidetes,1IU6V@117747|Sphingobacteriia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
HKD3_k127_6423978_1	1122605.KB893626_gene2525	1.832e-104	344.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1INPX@117747|Sphingobacteriia	976|Bacteroidetes	C	oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_6423978_5	1123248.KB893319_gene3968	2.209e-69	239.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1IST1@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_6424011_2	313596.RB2501_00161	3.476e-13	71.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1I28K@117743|Flavobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
HKD3_k127_6424011_0	1185876.BN8_03379	1.315e-218	700.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
HKD3_k127_6424011_1	1450525.JATV01000006_gene1131	9.782e-204	644.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,1HX95@117743|Flavobacteriia,2NTHP@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_6449643_6	700598.Niako_0927	0.0004604	43.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_6449643_2	1123248.KB893348_gene192	8.174e-91	308.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IXJN@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6449643_4	1123248.KB893348_gene193	1.893e-48	179.0	COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_6449643_0	1123248.KB893348_gene194	1.418e-197	650.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,1IWR7@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD3_k127_6449643_3	1123248.KB893348_gene195	1.324e-85	290.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1ISF2@117747|Sphingobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_6449643_5	485918.Cpin_6314	4.277e-17	88.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
HKD3_k127_6449643_1	925409.KI911562_gene472	2.983e-117	380.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HKD3_k127_6456200_0	1267211.KI669560_gene806	1.336e-219	690.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1IQI6@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1233 Phytoene dehydrogenase and related	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_6456200_3	1267211.KI669560_gene807	2.777e-135	435.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1IP80@117747|Sphingobacteriia	976|Bacteroidetes	I	Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
HKD3_k127_6456200_6	700598.Niako_6788	7.206e-65	227.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1ISDP@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
HKD3_k127_6456200_1	1267211.KI669560_gene809	1.302e-180	578.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_6456200_7	1123248.KB893348_gene314	7.709e-53	198.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,1IT8X@117747|Sphingobacteriia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
HKD3_k127_6456200_5	313598.MED152_02565	3.106e-78	263.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1I1A9@117743|Flavobacteriia,3VWIH@52959|Polaribacter	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
HKD3_k127_6456200_4	1123248.KB893314_gene3610	1.127e-103	349.0	COG0644@1|root,COG0644@2|Bacteria,4NDTU@976|Bacteroidetes,1J0IB@117747|Sphingobacteriia	976|Bacteroidetes	C	Lycopene cyclase protein	crtY	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
HKD3_k127_6456200_2	398720.MED217_17470	1.034e-169	545.0	COG0520@1|root,COG0520@2|Bacteria,4NM0W@976|Bacteroidetes,1I00M@117743|Flavobacteriia,2XJWU@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD3_k127_6463755_35	1218103.CIN01S_09_03430	3.484e-07	56.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,4NEVK@976|Bacteroidetes,1HYB7@117743|Flavobacteriia,3ZR0J@59732|Chryseobacterium	976|Bacteroidetes	G	1,4-alpha-glucan branching protein	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
HKD3_k127_6463755_28	742817.HMPREF9449_01514	8.625e-36	147.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,2FNYD@200643|Bacteroidia,231T1@171551|Porphyromonadaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
HKD3_k127_6463755_8	1123248.KB893314_gene3370	2.226e-135	461.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
HKD3_k127_6463755_12	1239962.C943_01576	4.017e-102	340.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,47NFE@768503|Cytophagia	976|Bacteroidetes	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
HKD3_k127_6463755_10	1120968.AUBX01000013_gene3490	5.764e-113	380.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47JN7@768503|Cytophagia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
HKD3_k127_6463755_13	519989.ECTPHS_06407	2.47e-97	340.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_6463755_29	1234364.AMSF01000010_gene549	5.355e-30	135.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,1RZBT@1236|Gammaproteobacteria,1X3JT@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_6463755_32	335543.Sfum_3346	2.491e-15	89.0	COG0438@1|root,COG0438@2|Bacteria,1NET7@1224|Proteobacteria,431AW@68525|delta/epsilon subdivisions,2WWRH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6463755_9	525897.Dbac_3261	4.661e-123	421.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WITC@28221|Deltaproteobacteria,2MAUJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_6463755_34	404380.Gbem_1790	4.538e-08	65.0	COG0438@1|root,COG0438@2|Bacteria,1RHQ2@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
HKD3_k127_6463755_33	1469607.KK073768_gene3000	6.449e-09	68.0	COG0438@1|root,COG0438@2|Bacteria,1GCZQ@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_6463755_14	700598.Niako_6572	2.131e-85	315.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1IW5H@117747|Sphingobacteriia	976|Bacteroidetes	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_6463755_26	1449063.JMLS01000036_gene6371	8.436e-41	174.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
HKD3_k127_6463755_36	314232.SKA53_01009	0.0001164	55.0	2EY4P@1|root,33RDH@2|Bacteria,1NSSZ@1224|Proteobacteria,2UQW0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6463755_16	595536.ADVE02000001_gene438	1.17e-81	284.0	COG4641@1|root,COG4641@2|Bacteria,1RBIX@1224|Proteobacteria,2U644@28211|Alphaproteobacteria,36Z8M@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
HKD3_k127_6463755_20	765912.Thimo_1003	2.475e-66	237.0	COG0438@1|root,COG0438@2|Bacteria,1N5HW@1224|Proteobacteria,1RPPH@1236|Gammaproteobacteria,1WY5F@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_6463755_31	272123.Anacy_3774	8.928e-18	95.0	COG0438@1|root,COG0438@2|Bacteria,1G32B@1117|Cyanobacteria,1HQ1N@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD3_k127_6463755_30	656024.FsymDg_1668	5.905e-26	117.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23
HKD3_k127_6463755_37	313589.JNB_18588	0.0008722	51.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2I90T@201174|Actinobacteria,4FEQD@85021|Intrasporangiaceae	201174|Actinobacteria	GM	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_6463755_18	485918.Cpin_4745	5.773e-72	257.0	COG1835@1|root,COG1835@2|Bacteria,4NNXT@976|Bacteroidetes,1IUGI@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD3_k127_6463755_19	517418.Ctha_2145	3.368e-68	244.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wbbK	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_6463755_21	365528.KB891219_gene1130	6.172e-59	223.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_6463755_0	391598.FBBAL38_02590	8.343e-314	975.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,4NFEW@976|Bacteroidetes,1HZIS@117743|Flavobacteriia	976|Bacteroidetes	E	Dehydrogenase	-	-	-	ko:K02030,ko:K03810	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ADH_zinc_N,GFO_IDH_MocA
HKD3_k127_6463755_23	335541.Swol_0701	4.108e-55	198.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	HTH_20,HTH_5,NTP_transf_2
HKD3_k127_6463755_6	743722.Sph21_1828	1.099e-160	513.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1IR9A@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
HKD3_k127_6463755_2	997884.HMPREF1068_02107	2.633e-210	670.0	COG5360@1|root,COG5360@2|Bacteria,4NH16@976|Bacteroidetes,2FRE8@200643|Bacteroidia,4APXY@815|Bacteroidaceae	976|Bacteroidetes	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
HKD3_k127_6463755_5	1034807.FBFL15_1579	2.684e-183	582.0	COG0438@1|root,COG0438@2|Bacteria,4NGU7@976|Bacteroidetes,1I01U@117743|Flavobacteriia,2NV5G@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_6463755_15	761193.Runsl_1720	8.157e-84	288.0	COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,47PNC@768503|Cytophagia	976|Bacteroidetes	M	PFAM Bacterial sugar transferase	wcgN	-	2.7.8.36	ko:K15915	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
HKD3_k127_6463755_22	483216.BACEGG_02128	3.454e-55	201.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,2FNDD@200643|Bacteroidia,4ANIF@815|Bacteroidaceae	976|Bacteroidetes	S	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	neuD	-	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
HKD3_k127_6463755_7	1453500.AT05_02280	1.096e-150	486.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_6463755_24	1123248.KB893314_gene3482	4.332e-52	196.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VanZ
HKD3_k127_6463755_17	700598.Niako_0568	5.033e-80	280.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,1IT7E@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
HKD3_k127_6463755_11	700598.Niako_0569	5.642e-110	360.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1IR2F@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
HKD3_k127_6463755_4	925409.KI911562_gene2596	1.407e-193	649.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1INZH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_6463755_3	700598.Niako_0571	9.589e-198	636.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,HHH_8,PHP
HKD3_k127_6463755_27	929713.NIASO_20375	4.714e-40	149.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1IT8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD3_k127_6463755_25	925409.KI911562_gene2592	7.005e-47	169.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1ISXI@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
HKD3_k127_6463755_1	925409.KI911562_gene2591	4.378e-218	681.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IP9C@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD3_k127_6477841_1	1270196.JCKI01000002_gene135	4.444e-161	522.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1IRKN@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HKD3_k127_6477841_0	929713.NIASO_00855	2.209e-199	629.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
HKD3_k127_6477841_2	700598.Niako_2206	1.741e-41	158.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_6477841_3	925409.KI911562_gene2069	1.563e-18	84.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes,1IPNT@117747|Sphingobacteriia	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_651519_20	929556.Solca_3167	3.394e-65	227.0	COG0110@1|root,COG0110@2|Bacteria,4NNPH@976|Bacteroidetes,1IXS6@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
HKD3_k127_651519_3	700598.Niako_1623	3.733e-254	803.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IP25@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
HKD3_k127_651519_19	1267211.KI669560_gene2004	5.835e-74	256.0	COG4399@1|root,COG4399@2|Bacteria,4NIDM@976|Bacteroidetes,1IZQF@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD3_k127_651519_4	700598.Niako_1621	5.304e-242	777.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_651519_17	925409.KI911562_gene2887	3.068e-88	296.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1IQ1X@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
HKD3_k127_651519_2	700598.Niako_2205	7.161e-272	846.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1IQYY@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD3_k127_651519_16	1123248.KB893330_gene395	8.44e-90	306.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1IXKD@117747|Sphingobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
HKD3_k127_651519_24	1239962.C943_00751	2.426e-29	137.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,47JQ1@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
HKD3_k127_651519_32	1396141.BATP01000020_gene111	1.097e-05	56.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_651519_10	485918.Cpin_5234	5.651e-130	443.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD3_k127_651519_5	925409.KI911562_gene1789	9.158e-217	681.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
HKD3_k127_651519_18	925409.KI911562_gene1790	8.388e-82	276.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
HKD3_k127_651519_13	700598.Niako_1990	3.448e-107	355.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1IPJH@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HKD3_k127_651519_22	1120966.AUBU01000006_gene3338	2.616e-43	158.0	COG4115@1|root,COG4115@2|Bacteria,4NSJD@976|Bacteroidetes,47S5K@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Addiction module toxin, Txe YoeB	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
HKD3_k127_651519_23	1120966.AUBU01000006_gene3339	8.269e-31	122.0	COG2161@1|root,COG2161@2|Bacteria,4NT64@976|Bacteroidetes	976|Bacteroidetes	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
HKD3_k127_651519_9	925409.KI911562_gene1792	7.852e-146	479.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1IP2Z@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane protein involved in aromatic hydrocarbon degradation	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
HKD3_k127_651519_1	925409.KI911562_gene1794	5.08e-276	855.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1IQ4M@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HKD3_k127_651519_30	1313421.JHBV01000041_gene3700	1.002e-19	94.0	2E6Q3@1|root,331AC@2|Bacteria,4NUP2@976|Bacteroidetes,1IU1U@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5362
HKD3_k127_651519_21	700598.Niako_2002	1.046e-45	175.0	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1IRZA@117747|Sphingobacteriia	976|Bacteroidetes	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD3_k127_651519_15	700598.Niako_2003	2.923e-102	343.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1IQH7@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Integral membrane protein DUF95	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
HKD3_k127_651519_31	391587.KAOT1_01604	5.141e-12	77.0	29GF6@1|root,303CZ@2|Bacteria,4NR6I@976|Bacteroidetes,1I2IF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
HKD3_k127_651519_27	1279009.ADICEAN_02370	4.81e-23	113.0	28IVH@1|root,2Z8TX@2|Bacteria,4NEEW@976|Bacteroidetes,47N52@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
HKD3_k127_651519_14	700598.Niako_4418	3.744e-103	340.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,1IPIE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_651519_7	700598.Niako_4417	4.764e-179	574.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_651519_0	700598.Niako_7335	0.0	1102.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1IPA1@117747|Sphingobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD3_k127_651519_29	1121904.ARBP01000001_gene5632	8.708e-21	109.0	28MEF@1|root,2ZAS2@2|Bacteria,4NINI@976|Bacteroidetes,47S3F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_651519_25	1379270.AUXF01000001_gene2369	6.855e-29	123.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
HKD3_k127_651519_12	391587.KAOT1_18422	1.469e-108	363.0	COG0463@1|root,COG0463@2|Bacteria,4PM7S@976|Bacteroidetes,1IMR6@117743|Flavobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_651519_11	469383.Cwoe_0091	4.351e-119	399.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria,4CR13@84995|Rubrobacteria	84995|Rubrobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	RPE65
HKD3_k127_651519_8	1121930.AQXG01000012_gene3233	6.12e-178	571.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1IQI6@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1233 Phytoene dehydrogenase and related	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD3_k127_651519_26	880071.Fleli_0769	1.882e-25	112.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,47S7U@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
HKD3_k127_651519_6	761193.Runsl_0828	2.463e-195	628.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,47Y3C@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_6519487_6	1121481.AUAS01000007_gene923	3.202e-26	111.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_6519487_0	925409.KI911562_gene1110	9.37e-233	724.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD3_k127_6519487_3	700598.Niako_6877	1.151e-97	325.0	COG0491@1|root,COG0491@2|Bacteria,4NHW8@976|Bacteroidetes,1IQ1J@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_6519487_2	1123248.KB893314_gene3429	5.371e-141	460.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1INPB@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HKD3_k127_6519487_1	925409.KI911562_gene361	2.398e-222	711.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD3_k127_6519487_5	504472.Slin_3257	1.058e-35	143.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,47Q0U@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_6519487_4	471854.Dfer_1022	2.947e-64	223.0	COG0664@1|root,COG0664@2|Bacteria,4NN09@976|Bacteroidetes,47PAQ@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_6582674_2	1267211.KI669560_gene2060	1.166e-152	491.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IV0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
HKD3_k127_6582674_4	1123248.KB893321_gene530	3.01e-69	239.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_6582674_3	525373.HMPREF0766_10348	1.137e-91	317.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
HKD3_k127_6582674_0	925409.KI911562_gene2438	3.405e-295	912.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IWY5@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
HKD3_k127_6582674_5	509635.N824_11590	1.566e-35	138.0	COG2076@1|root,COG2076@2|Bacteria,4NQ4U@976|Bacteroidetes,1IY5Z@117747|Sphingobacteriia	976|Bacteroidetes	P	Small Multidrug Resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
HKD3_k127_6582674_1	700598.Niako_1161	2.293e-171	542.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD3_k127_663532_0	1123248.KB893386_gene1900	9.251e-227	719.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_663532_3	485918.Cpin_0678	6.981e-83	291.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD3_k127_663532_2	1267211.KI669560_gene1052	4.933e-95	317.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1INKY@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD3_k127_663532_1	700598.Niako_5629	6.931e-226	703.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1IPCY@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD3_k127_6644327_1	1121895.Q765_04530	6.242e-50	182.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1I1AY@117743|Flavobacteriia,2NT7W@237|Flavobacterium	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K20459	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
HKD3_k127_6644327_0	1121957.ATVL01000009_gene1158	7.718e-140	454.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,47N3E@768503|Cytophagia	976|Bacteroidetes	G	Beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_6650707_2	925409.KI911562_gene2795	1.476e-143	458.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD3_k127_6650707_0	1123248.KB893317_gene4326	1.224e-249	781.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD3_k127_6650707_3	1123248.KB893317_gene4325	1.955e-114	379.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1IPH1@117747|Sphingobacteriia	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
HKD3_k127_6650707_1	700598.Niako_4510	1.319e-185	586.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1IW5P@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_6650707_4	700598.Niako_4511	1.425e-112	370.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1IQJU@117747|Sphingobacteriia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
HKD3_k127_6650707_5	1123248.KB893317_gene4321	1.207e-74	254.0	COG1595@1|root,COG1595@2|Bacteria,4NM40@976|Bacteroidetes,1IRKZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
HKD3_k127_6650707_6	700598.Niako_4426	1.34e-09	60.0	COG0265@1|root,COG0265@2|Bacteria,4NGA4@976|Bacteroidetes,1IPPQ@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
HKD3_k127_667887_2	760192.Halhy_5404	2.802e-60	214.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1INWH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycoside hydrolase, family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_667887_0	391596.PBAL39_02397	3.415e-245	768.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IV50@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD3_k127_667887_1	929556.Solca_4479	1.546e-142	459.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_6693292_3	1123248.KB893326_gene1410	1.838e-95	339.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K02014,ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000,ko02042	1.B.14	-	-	Alginate_lyase2,CBM_6,CarbopepD_reg_2,F5_F8_type_C,Plug,Thiol_cytolys_C,Thiol_cytolysin,TonB_dep_Rec
HKD3_k127_6693292_0	925409.KI911562_gene51	4.501e-182	576.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD3_k127_6693292_4	1267211.KI669560_gene2536	2.323e-88	300.0	COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,1IS83@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD3_k127_6693292_2	1267211.KI669560_gene2535	1.6e-137	445.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1IQEQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HKD3_k127_6693292_7	1123248.KB893323_gene1617	5.386e-45	168.0	2DKFZ@1|root,309D6@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HKD3_k127_6693292_6	1123248.KB893370_gene5146	2.764e-52	189.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes	976|Bacteroidetes	I	Biotin carboxyl carrier protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
HKD3_k127_6693292_1	1123248.KB893370_gene5145	8.575e-157	499.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1IPSQ@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01965,ko:K01968	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00373,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_672925_0	504472.Slin_5068	3.653e-139	452.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,47JWZ@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
HKD3_k127_6777190_3	1265505.ATUG01000003_gene289	3.499e-27	112.0	COG0454@1|root,COG0456@2|Bacteria,1Q1ZZ@1224|Proteobacteria,42USA@68525|delta/epsilon subdivisions,2WQ2Q@28221|Deltaproteobacteria,2MPQY@213118|Desulfobacterales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_6777190_1	388413.ALPR1_03905	1.667e-96	331.0	2E9KV@1|root,333TK@2|Bacteria,4NWD3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
HKD3_k127_6777190_0	1123248.KB893348_gene80	1.77e-314	976.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD3_k127_6777190_2	700598.Niako_4517	6.093e-34	134.0	2EFPT@1|root,339FT@2|Bacteria,4NV1V@976|Bacteroidetes,1IU65@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6784368_2	700598.Niako_6359	4.929e-120	387.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HKD3_k127_6784368_3	1122605.KB893626_gene2383	2.787e-100	336.0	COG3000@1|root,COG3000@2|Bacteria,4NI62@976|Bacteroidetes	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_6784368_5	700598.Niako_4519	1.352e-21	102.0	2EDN0@1|root,337HT@2|Bacteria,4NVQJ@976|Bacteroidetes,1ITXS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6784368_4	700598.Niako_4518	1.34e-63	223.0	COG1595@1|root,COG1595@2|Bacteria,4NP02@976|Bacteroidetes,1J06I@117747|Sphingobacteriia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6784368_1	880070.Cycma_4553	3.136e-205	651.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,4NM18@976|Bacteroidetes,47XKA@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
HKD3_k127_6784368_0	760192.Halhy_6513	0.0	1750.0	COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HKD3_k127_6797092_0	700598.Niako_7354	1.899e-207	653.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1IQY4@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
HKD3_k127_6797092_2	700598.Niako_7353	2.708e-79	271.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1INYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD3_k127_6797092_3	504472.Slin_4683	4.83e-64	222.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,47Q23@768503|Cytophagia	976|Bacteroidetes	L	transposase IS200-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD3_k127_6797092_1	1267211.KI669560_gene2684	8.714e-174	563.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1IQXN@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
HKD3_k127_680001_9	1166018.FAES_3618	7.274e-37	141.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,47MUJ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD3_k127_680001_5	925409.KI911562_gene2271	6.915e-72	246.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1IRWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
HKD3_k127_680001_3	700598.Niako_2019	3.572e-92	317.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD3_k127_680001_7	700598.Niako_5621	2.219e-57	211.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,1IU2K@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_680001_8	760192.Halhy_4542	5.657e-57	210.0	COG0500@1|root,COG0500@2|Bacteria,4PM23@976|Bacteroidetes,1J0XJ@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD3_k127_680001_4	761193.Runsl_5388	8.364e-73	256.0	COG3358@1|root,COG3358@2|Bacteria,4NFT3@976|Bacteroidetes,47NJY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
HKD3_k127_680001_6	925409.KI911562_gene183	7.781e-66	233.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1IRUN@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_680001_0	925409.KI911562_gene184	8.279e-218	706.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1IPV4@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HKD3_k127_680001_2	1346330.M472_14680	1.311e-114	378.0	COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1IR1D@117747|Sphingobacteriia	976|Bacteroidetes	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
HKD3_k127_680001_1	929713.NIASO_05760	1.835e-130	434.0	COG1807@1|root,COG1807@2|Bacteria,4NHXW@976|Bacteroidetes,1IR5R@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_680001_10	1123234.AUKI01000017_gene2508	4.907e-19	90.0	COG0667@1|root,COG0667@2|Bacteria,4NF06@976|Bacteroidetes,1HZ2C@117743|Flavobacteriia	976|Bacteroidetes	C	Aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_682658_0	925409.KI911562_gene1820	4.739e-291	910.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,4NGF6@976|Bacteroidetes,1IQ4D@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	nhaA	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
HKD3_k127_682658_1	700598.Niako_6637	9.87e-128	418.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_682658_4	1144275.COCOR_06149	7.255e-21	107.0	COG0457@1|root,COG0457@2|Bacteria,1Q1X1@1224|Proteobacteria,437J0@68525|delta/epsilon subdivisions,2WYKS@28221|Deltaproteobacteria,2Z2BC@29|Myxococcales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
HKD3_k127_682658_2	700598.Niako_6625	1.02e-100	334.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_682658_3	925409.KI911562_gene1089	2.064e-40	153.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_6845648_7	1237149.C900_02493	9.69e-36	140.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
HKD3_k127_6845648_8	926549.KI421517_gene2251	4.592e-29	123.0	COG0824@1|root,COG0824@2|Bacteria,4NSIG@976|Bacteroidetes,47S22@768503|Cytophagia	976|Bacteroidetes	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
HKD3_k127_6845648_0	1267211.KI669560_gene1269	1.219e-230	741.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
HKD3_k127_6845648_9	929713.NIASO_10290	7.62e-17	94.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K02487,ko:K13582	ko02020,ko04112,map02020,map04112	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	DUF4157,DUF4476,NLPC_P60,PG_binding_1,Sel1
HKD3_k127_6845648_4	925409.KI911562_gene1549	3.617e-88	299.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1IPUQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD3_k127_6845648_5	700598.Niako_5543	6.145e-49	188.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1ISMS@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_6845648_2	700598.Niako_5542	6.071e-102	337.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1IQ48@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HKD3_k127_6845648_3	700598.Niako_0167	1.557e-100	332.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_6845648_1	700598.Niako_0168	1.049e-132	429.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HKD3_k127_6845648_6	1123248.KB893381_gene1074	1.915e-47	181.0	COG1555@1|root,COG1555@2|Bacteria,4NUGB@976|Bacteroidetes,1J0F4@117747|Sphingobacteriia	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6854409_2	1122194.AUHU01000008_gene3306	3.945e-05	54.0	COG1266@1|root,COG1266@2|Bacteria,1R5BW@1224|Proteobacteria,1RQKF@1236|Gammaproteobacteria,469V9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD3_k127_6854409_1	1123248.KB893386_gene1981	7.047e-24	114.0	COG2373@1|root,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,1IQ4C@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Plug
HKD3_k127_6854409_0	1122605.KB893626_gene2579	2.812e-65	223.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1IPG1@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HKD3_k127_6884857_6	1450525.JATV01000003_gene1744	4.009e-21	98.0	2E4J8@1|root,32ZEA@2|Bacteria,4NW6Q@976|Bacteroidetes,1I69T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2541
HKD3_k127_6884857_2	1239962.C943_03833	5.574e-125	409.0	COG5492@1|root,COG5492@2|Bacteria,4NPS9@976|Bacteroidetes	976|Bacteroidetes	N	Putative carbohydrate metabolism domain	-	-	-	-	-	-	-	-	-	-	-	-	PCMD
HKD3_k127_6884857_4	1239962.C943_03832	5.782e-76	261.0	2DNY3@1|root,32ZR7@2|Bacteria,4NWGU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6884857_5	1239962.C943_03831	1.944e-50	183.0	2C0UK@1|root,32ZTA@2|Bacteria,4NUQ2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6884857_0	1433126.BN938_2808	5.974e-202	646.0	COG3203@1|root,COG3203@2|Bacteria,4NPX9@976|Bacteroidetes,2FXT1@200643|Bacteroidia	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
HKD3_k127_6884857_1	1239962.C943_03829	3.133e-141	451.0	COG1028@1|root,COG1028@2|Bacteria	1239962.C943_03829|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6884857_3	1239962.C943_03828	5.393e-122	396.0	COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,47MT3@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.159,1.3.1.25	ko:K00076,ko:K05783	ko00121,ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00121,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113	RC00271,RC01326,RC01327	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD3_k127_6978300_2	925409.KI911562_gene1575	1.58e-39	150.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IXCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD3_k127_6978300_1	700598.Niako_4591	4.495e-51	187.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISG3@117747|Sphingobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
HKD3_k127_6978300_0	925409.KI911562_gene1573	1.374e-146	466.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1IRAS@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HKD3_k127_6978300_3	1121481.AUAS01000004_gene1390	1.739e-33	136.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,47QK5@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_6978300_4	1123248.KB893381_gene1034	4.168e-10	60.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD3_k127_6996439_0	700598.Niako_5603	2.085e-225	704.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1IQYP@117747|Sphingobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD3_k127_6996439_1	929556.Solca_3212	2.302e-117	385.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,1IR9X@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	ykoT	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
HKD3_k127_7009345_3	700598.Niako_6354	1.286e-62	218.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IXQH@117747|Sphingobacteriia	976|Bacteroidetes	M	Cytidylyltransferase	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
HKD3_k127_7009345_1	761193.Runsl_5621	5.652e-182	585.0	COG0151@1|root,COG0151@2|Bacteria,4P144@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7009345_0	1267211.KI669560_gene542	5.625e-186	586.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes	976|Bacteroidetes	C	alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
HKD3_k127_7009345_4	1313301.AUGC01000006_gene133	0.000955	49.0	2E9XE@1|root,33436@2|Bacteria,4NV30@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7009345_2	925409.KI911562_gene479	6.448e-156	498.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD3_k127_7027125_2	700598.Niako_3956	4.965e-94	314.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1IRTX@117747|Sphingobacteriia	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
HKD3_k127_7027125_3	1150600.ADIARSV_1291	8.308e-57	206.0	COG2867@1|root,COG2867@2|Bacteria,4NNHS@976|Bacteroidetes,1ISH1@117747|Sphingobacteriia	976|Bacteroidetes	I	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
HKD3_k127_7027125_1	251221.35210936	1.3e-187	602.0	COG1574@1|root,COG1574@2|Bacteria,1G40U@1117|Cyanobacteria	1117|Cyanobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_7027125_0	760192.Halhy_4898	0.0	1501.0	COG3250@1|root,COG3867@1|root,COG3250@2|Bacteria,COG3867@2|Bacteria,4NEWN@976|Bacteroidetes,1IRAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_709336_4	925409.KI911562_gene253	9.958e-79	269.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1IS50@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD3_k127_709336_2	1123248.KB893315_gene3013	1.334e-116	384.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1J0PK@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_709336_3	700598.Niako_7008	3.248e-102	337.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1IR1N@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HKD3_k127_709336_1	700598.Niako_7009	4.044e-154	498.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1IWIT@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
HKD3_k127_709336_5	925409.KI911562_gene1611	7.656e-77	263.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1IRTF@117747|Sphingobacteriia	976|Bacteroidetes	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
HKD3_k127_709336_0	700598.Niako_4525	1.039e-159	510.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1IPSH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_709505_2	1267211.KI669560_gene2835	1.136e-270	839.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes	976|Bacteroidetes	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_709505_12	1123248.KB893355_gene4712	1.613e-54	193.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
HKD3_k127_709505_11	1123248.KB893355_gene4713	1.641e-74	263.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1IPUT@117747|Sphingobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_709505_8	1484460.JSWG01000011_gene1711	9.732e-175	564.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
HKD3_k127_709505_16	391598.FBBAL38_01760	8.81e-15	77.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HKD3_k127_709505_14	688270.Celal_1853	1.225e-21	95.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HKD3_k127_709505_10	925409.KI911562_gene300	6.281e-150	486.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD3_k127_709505_3	1047013.AQSP01000142_gene192	6.964e-257	814.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
HKD3_k127_709505_4	925409.KI911562_gene299	3.894e-218	689.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HKD3_k127_709505_7	313590.MED134_14256	6.91e-175	560.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia,37EUX@326319|Dokdonia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_709505_1	929703.KE386491_gene4114	1.279e-300	939.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47JE7@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
HKD3_k127_709505_0	925409.KI911562_gene302	0.0	1037.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD3_k127_709505_13	929556.Solca_3789	1.996e-25	111.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1ITMU@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
HKD3_k127_709505_9	760192.Halhy_3752	4.369e-157	510.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,1IW1W@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_709505_6	504472.Slin_4261	4.187e-191	609.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
HKD3_k127_709505_5	929713.NIASO_18990	7.561e-195	621.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1IP0T@117747|Sphingobacteriia	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
HKD3_k127_709505_15	1122605.KB893628_gene4544	6.624e-18	85.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD3_k127_7098546_1	925409.KI911562_gene2326	5.116e-152	497.0	COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,1IW8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
HKD3_k127_7098546_0	1123248.KB893322_gene605	1.085e-203	639.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1INYF@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_7098546_2	700598.Niako_5587	6.983e-112	369.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD3_k127_7184508_5	700598.Niako_6495	5.37e-52	190.0	COG1846@1|root,COG1846@2|Bacteria,4NSNN@976|Bacteroidetes,1ITUW@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD3_k127_7184508_0	1267211.KI669560_gene96	2.163e-301	934.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_7184508_4	247633.GP2143_08674	4.543e-147	474.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1J4FV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1810	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
HKD3_k127_7184508_7	565045.NOR51B_246	2.064e-28	117.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3288 NAD NADP transhydrogenase alpha subunit	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
HKD3_k127_7184508_2	1121403.AUCV01000007_gene1233	6.535e-156	504.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2MIF6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
HKD3_k127_7184508_9	1121104.AQXH01000008_gene2376	9.384e-05	47.0	2ESUZ@1|root,33KDD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7184508_6	1123248.KB893348_gene139	4.125e-46	168.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,1ITA6@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD3_k127_7184508_1	700598.Niako_6198	2.056e-179	567.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
HKD3_k127_7184508_8	1313301.AUGC01000005_gene264	1.44e-16	81.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S ferredoxin	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
HKD3_k127_7184508_3	929703.KE386491_gene2307	5.779e-150	486.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,47MR2@768503|Cytophagia	976|Bacteroidetes	O	Peptidase family U32	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
HKD3_k127_7221496_3	1267211.KI669560_gene1215	7.591e-51	186.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_7221496_1	468059.AUHA01000005_gene2577	1.22e-110	361.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD3_k127_7221496_0	485917.Phep_2918	6.205e-124	400.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD3_k127_7221496_4	925409.KI911562_gene3005	3.243e-09	63.0	2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
HKD3_k127_7221496_2	700598.Niako_5109	3.148e-68	236.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
HKD3_k127_7252534_1	1173028.ANKO01000194_gene6028	1.384e-39	162.0	COG3250@1|root,COG3250@2|Bacteria,1G4FY@1117|Cyanobacteria,1HA7W@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_7252534_2	1123400.KB904816_gene1583	1.063e-16	93.0	COG3250@1|root,COG3250@2|Bacteria,1MXXM@1224|Proteobacteria,1RYMD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	BetaGal_dom4_5,Glyco_hydro_2_N,SASA
HKD3_k127_7252534_0	742727.HMPREF9447_04504	4.017e-171	554.0	2F8GI@1|root,340VC@2|Bacteria,4PFIS@976|Bacteroidetes,2FWVT@200643|Bacteroidia,4ATI0@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7267254_2	485918.Cpin_4672	1.897e-152	491.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,1IQPN@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_7267254_0	1123278.KB893564_gene2597	3.755e-243	770.0	COG0644@1|root,COG0644@2|Bacteria,4P07W@976|Bacteroidetes,47N5I@768503|Cytophagia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HKD3_k127_7267254_1	1195236.CTER_5362	6.271e-158	524.0	COG1331@1|root,COG1331@2|Bacteria,1VQ0S@1239|Firmicutes,24ZUZ@186801|Clostridia	186801|Clostridia	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7267254_3	1235803.C825_03122	5.293e-41	159.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMQ9@200643|Bacteroidia,22WY7@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_7268198_8	313603.FB2170_03915	1.037e-91	308.0	COG2755@1|root,COG2755@2|Bacteria,4NK31@976|Bacteroidetes,1IJC8@117743|Flavobacteriia	976|Bacteroidetes	E	Sialate O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2,SASA
HKD3_k127_7268198_1	929556.Solca_2168	0.0	1019.0	COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes,1IWSP@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,fn3
HKD3_k127_7268198_0	1267211.KI669560_gene1074	0.0	1032.0	COG2755@1|root,COG3525@1|root,COG2755@2|Bacteria,COG3525@2|Bacteria,4NF9Z@976|Bacteroidetes,1IVUQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
HKD3_k127_7268198_18	1089547.KB913013_gene4738	0.0001406	54.0	COG1577@1|root,COG2911@1|root,COG1577@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	mvaK2	-	2.7.1.36,2.7.4.2	ko:K00869,ko:K00938,ko:K20276	ko00900,ko01100,ko01110,ko01130,ko02024,ko04146,map00900,map01100,map01110,map01130,map02024,map04146	M00095	R02245,R03245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_7268198_16	504472.Slin_0490	6.991e-11	75.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Collagen,F5_F8_type_C,Laminin_G_3,PKD,Ricin_B_lectin,SASA,SLH
HKD3_k127_7268198_13	1469557.JSWF01000035_gene1076	1.091e-34	150.0	COG1404@1|root,COG1404@2|Bacteria,4NRWQ@976|Bacteroidetes,1I3TQ@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7268198_15	1121904.ARBP01000036_gene2101	6.336e-27	123.0	2EUGI@1|root,33MYS@2|Bacteria,4NZ1U@976|Bacteroidetes,47T7V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7268198_2	1297742.A176_00022	5.009e-147	471.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
HKD3_k127_7268198_4	1267211.KI669560_gene2870	1.509e-97	324.0	COG4760@1|root,COG4760@2|Bacteria,4NNIN@976|Bacteroidetes,1IXW4@117747|Sphingobacteriia	976|Bacteroidetes	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
HKD3_k127_7268198_12	1189612.A33Q_0621	1.328e-37	154.0	28J3Q@1|root,32URP@2|Bacteria,4NT50@976|Bacteroidetes,47R3P@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD3_k127_7268198_7	700598.Niako_6443	3.659e-95	330.0	COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,1IWXD@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_7268198_6	700598.Niako_6444	1.439e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,4NMAD@976|Bacteroidetes,1J08B@117747|Sphingobacteriia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_7268198_14	1120965.AUBV01000003_gene445	1.866e-28	122.0	2DNUQ@1|root,32Z94@2|Bacteria,4NVH0@976|Bacteroidetes,47QAG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
HKD3_k127_7268198_3	925409.KI911562_gene904	6.763e-123	400.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1IPZH@117747|Sphingobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HKD3_k127_7268198_9	484018.BACPLE_00979	2.936e-83	312.0	COG4249@1|root,COG4249@2|Bacteria,4NJZ8@976|Bacteroidetes,2FUN9@200643|Bacteroidia,4AVP2@815|Bacteroidaceae	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
HKD3_k127_7268198_17	373994.Riv7116_3545	6.518e-05	54.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1HJWW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_2,TPR_8
HKD3_k127_7268198_11	221288.JH992901_gene2934	1.603e-65	258.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1JKJ2@1189|Stigonemataceae	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
HKD3_k127_7268198_10	1279009.ADICEAN_01609	3.538e-74	274.0	COG4249@1|root,COG4249@2|Bacteria,4NH9I@976|Bacteroidetes,47V1R@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
HKD3_k127_7268198_5	761193.Runsl_1994	8.374e-96	317.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JJV@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD3_k127_7284687_6	313598.MED152_02580	2.135e-67	238.0	29UQ5@1|root,30G1W@2|Bacteria,4NKX5@976|Bacteroidetes,1I279@117743|Flavobacteriia,3VWUN@52959|Polaribacter	976|Bacteroidetes	C	spheroidene monooxygenase	crtA	-	-	-	-	-	-	-	-	-	-	-	DUF3291
HKD3_k127_7284687_8	1227739.Hsw_0315	3.755e-39	158.0	COG2518@1|root,COG2518@2|Bacteria,4NR16@976|Bacteroidetes,47RRS@768503|Cytophagia	976|Bacteroidetes	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HKD3_k127_7284687_1	485918.Cpin_6540	1.045e-137	456.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1IP8V@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HKD3_k127_7284687_3	925409.KI911562_gene2778	1.135e-112	371.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1ISQ1@117747|Sphingobacteriia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD3_k127_7284687_2	925409.KI911562_gene2779	1.423e-136	438.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1INX0@117747|Sphingobacteriia	976|Bacteroidetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
HKD3_k127_7284687_7	1123248.KB893316_gene4560	2.377e-60	224.0	2F5WP@1|root,33YFF@2|Bacteria,4P47E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7284687_4	1267211.KI669560_gene2091	1.526e-88	299.0	COG2382@1|root,COG2382@2|Bacteria,4NI86@976|Bacteroidetes,1IQ5J@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD3_k127_7284687_9	925409.KI911562_gene283	5.741e-23	109.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1IT51@117747|Sphingobacteriia	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_7284687_0	1123248.KB893315_gene3125	4.529e-283	890.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_7284687_10	153721.MYP_3680	3.658e-07	60.0	COG2849@1|root,COG2849@2|Bacteria,4NSYD@976|Bacteroidetes,47RIN@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD3_k127_7284687_5	700598.Niako_0372	1.435e-83	303.0	COG0457@1|root,COG1729@1|root,COG3147@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3147@2|Bacteria,4NDV9@976|Bacteroidetes,1IQQP@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
HKD3_k127_7302846_12	485918.Cpin_3090	5.741e-129	419.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1IPD8@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD3_k127_7302846_30	1123248.KB893323_gene1572	5.606e-23	98.0	2ACFD@1|root,31210@2|Bacteria,4PGVP@976|Bacteroidetes,1IUGW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
HKD3_k127_7302846_26	929713.NIASO_08930	3.165e-29	117.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1IU0P@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD3_k127_7302846_25	485918.Cpin_3087	2.201e-33	130.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1IUBT@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD3_k127_7302846_8	1267211.KI669560_gene1593	4.449e-220	687.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1INU3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_7302846_11	1122605.KB893625_gene2110	5.5e-136	441.0	COG3239@1|root,COG3239@2|Bacteria,4NHPQ@976|Bacteroidetes	976|Bacteroidetes	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
HKD3_k127_7302846_22	1123248.KB893321_gene547	1.912e-67	235.0	COG0652@1|root,COG0652@2|Bacteria,4NRWP@976|Bacteroidetes	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HKD3_k127_7302846_10	1089547.KB913013_gene2324	2.785e-151	488.0	COG1858@1|root,COG1858@2|Bacteria,4NJGU@976|Bacteroidetes,47NXP@768503|Cytophagia	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
HKD3_k127_7302846_23	573370.DMR_27390	4.412e-49	196.0	COG5434@1|root,COG5434@2|Bacteria,1QYGC@1224|Proteobacteria,43CCG@68525|delta/epsilon subdivisions,2WR1K@28221|Deltaproteobacteria,2ME0C@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
HKD3_k127_7302846_1	485918.Cpin_1305	9.84e-321	990.0	COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD3_k127_7302846_4	1267211.KI669560_gene1618	4.521e-241	752.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1ISNT@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S10	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
HKD3_k127_7302846_20	1123057.P872_07695	4.447e-70	250.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7302846_5	925409.KI911562_gene2360	2.592e-234	732.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1IQ2K@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
HKD3_k127_7302846_24	1123248.KB893314_gene3652	2.155e-33	137.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1IU5B@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HKD3_k127_7302846_28	376686.Fjoh_3510	4.954e-24	110.0	COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,1I1IJ@117743|Flavobacteriia,2NTQM@237|Flavobacterium	976|Bacteroidetes	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
HKD3_k127_7302846_21	700598.Niako_1004	1.174e-68	239.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS97@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HKD3_k127_7302846_17	925409.KI911562_gene2490	2.713e-84	292.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IQZY@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HKD3_k127_7302846_19	1123248.KB893326_gene1426	3.159e-74	261.0	COG0860@1|root,COG0860@2|Bacteria,4P1J0@976|Bacteroidetes,1IVQV@117747|Sphingobacteriia	976|Bacteroidetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD3_k127_7302846_2	700598.Niako_1224	1.938e-300	946.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7302846_18	1123248.KB893337_gene2515	1.199e-82	281.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1IS1B@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_7302846_14	925409.KI911562_gene2486	1.275e-104	345.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1IQ5P@117747|Sphingobacteriia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HKD3_k127_7302846_3	1229276.DI53_0114	1.578e-257	825.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4NG28@976|Bacteroidetes,1IQJ9@117747|Sphingobacteriia	976|Bacteroidetes	KT	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
HKD3_k127_7302846_0	1150600.ADIARSV_1364	0.0	1224.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IPI6@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7302846_7	1150600.ADIARSV_1363	1.127e-220	693.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1IQB0@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_7302846_9	906888.JCM19314_1533	2.509e-167	548.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia,3HKV5@363408|Nonlabens	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
HKD3_k127_7302846_15	1150600.ADIARSV_1361	1.569e-96	324.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1IUMA@117747|Sphingobacteriia	976|Bacteroidetes	G	hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7302846_13	1150600.ADIARSV_1360	3.918e-113	375.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1IPEW@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
HKD3_k127_7302846_16	1150600.ADIARSV_1360	9.941e-94	315.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1IPEW@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
HKD3_k127_7302846_6	1454007.JAUG01000054_gene2592	3.822e-224	713.0	COG0383@1|root,COG0383@2|Bacteria,4NGF5@976|Bacteroidetes,1IPJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 38 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_38,Glyco_hydro_38C
HKD3_k127_7312422_3	485917.Phep_1372	9.579e-49	179.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1ITIM@117747|Sphingobacteriia	976|Bacteroidetes	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD3_k127_7312422_1	1237149.C900_01633	1.171e-185	589.0	COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,47P29@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_7312422_2	1550091.JROE01000005_gene2110	4.394e-156	519.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,1IW7F@117747|Sphingobacteriia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_7312422_0	471854.Dfer_2166	1.889e-229	717.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
HKD3_k127_7318457_3	714943.Mucpa_3169	3.777e-48	188.0	28HMX@1|root,2Z7WB@2|Bacteria,4NFY2@976|Bacteroidetes,1IPRK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7318457_0	1123248.KB893315_gene3175	6.223e-123	398.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD3_k127_7318457_1	1267211.KI669560_gene2038	5.626e-122	395.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HKD3_k127_7318457_2	700598.Niako_4423	6.991e-59	209.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_7340024_2	1408473.JHXO01000004_gene31	1.897e-13	76.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_7340024_0	700598.Niako_5094	8.523e-246	766.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1IPBW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HKD3_k127_7340024_1	1123248.KB893320_gene3871	5.774e-92	308.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
HKD3_k127_7354212_2	925409.KI911562_gene2343	1.018e-69	241.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_7354212_0	925409.KI911562_gene2064	3.765e-255	791.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HKD3_k127_7354212_3	1123248.KB893318_gene4245	2.86e-60	211.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1ISBR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
HKD3_k127_7354212_1	700598.Niako_4454	4.136e-177	561.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1IPSN@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HKD3_k127_7380480_7	700598.Niako_7323	4.828e-37	143.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD3_k127_7380480_2	700598.Niako_7324	7.878e-170	546.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_7380480_6	925409.KI911562_gene104	4.357e-53	200.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IRV2@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
HKD3_k127_7380480_0	700598.Niako_7326	4.093e-202	642.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1IQJQ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
HKD3_k127_7380480_1	700598.Niako_7327	1.733e-190	615.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1IR5B@117747|Sphingobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HKD3_k127_7380480_4	1123248.KB893386_gene1980	4.054e-104	347.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1IQB7@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
HKD3_k127_7380480_5	700598.Niako_7329	9.214e-54	198.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,1IZB2@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
HKD3_k127_7380480_3	700598.Niako_7330	1.662e-110	367.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1IVCP@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_7382047_0	1123248.KB893340_gene2669	0.0	1045.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1IR7Y@117747|Sphingobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HKD3_k127_7382047_2	761193.Runsl_2289	1.084e-12	80.0	2E9XE@1|root,33436@2|Bacteria,4NV30@976|Bacteroidetes,47T7H@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7382047_1	761193.Runsl_0552	1.674e-202	640.0	28KCX@1|root,2Z9ZQ@2|Bacteria,4NJ7S@976|Bacteroidetes,47JNB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7382047_3	700598.Niako_5416	5.166e-06	48.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD3_k127_7386374_1	1122605.KB893625_gene2308	1.275e-137	445.0	COG1092@1|root,COG1092@2|Bacteria,4P1C0@976|Bacteroidetes,1IVC8@117747|Sphingobacteriia	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HKD3_k127_7386374_2	1120966.AUBU01000014_gene573	1.374e-106	352.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia	976|Bacteroidetes	O	membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD3_k127_7386374_4	485918.Cpin_1881	1.198e-15	78.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1IUPB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
HKD3_k127_7386374_0	761193.Runsl_2021	3.077e-151	487.0	COG5434@1|root,COG5434@2|Bacteria,4NE9Y@976|Bacteroidetes,47KM6@768503|Cytophagia	976|Bacteroidetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD3_k127_7386374_3	1123278.KB893605_gene1748	1.264e-62	222.0	COG5434@1|root,COG5434@2|Bacteria,4NFZJ@976|Bacteroidetes,47K9P@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,fn3
HKD3_k127_738667_4	509635.N824_20000	1.19e-09	60.0	COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,1IPAR@117747|Sphingobacteriia	976|Bacteroidetes	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
HKD3_k127_738667_0	1122605.KB893639_gene3044	2.015e-270	836.0	COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,1IQYR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD3_k127_738667_1	929713.NIASO_04925	1.285e-167	533.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,1IQ1F@117747|Sphingobacteriia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
HKD3_k127_738667_2	1120966.AUBU01000010_gene2938	2.762e-31	133.0	COG4244@1|root,COG4244@2|Bacteria,4PN2J@976|Bacteroidetes	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,PSCyt1
HKD3_k127_738667_3	471854.Dfer_1976	4.423e-12	69.0	COG4244@1|root,COG4886@1|root,COG4244@2|Bacteria,COG4886@2|Bacteria,4NG07@976|Bacteroidetes,47K53@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
HKD3_k127_7403639_5	1123248.KB893348_gene342	2.836e-143	460.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1INN5@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
HKD3_k127_7403639_22	1519464.HY22_00465	4.277e-68	243.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HKD3_k127_7403639_13	925409.KI911562_gene486	5.711e-112	369.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,1IPES@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
HKD3_k127_7403639_29	1270196.JCKI01000008_gene1425	4.569e-46	176.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5
HKD3_k127_7403639_20	1288963.ADIS_0322	3.913e-78	273.0	COG1216@1|root,COG1216@2|Bacteria,4NJHF@976|Bacteroidetes,47P3J@768503|Cytophagia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD3_k127_7403639_12	485918.Cpin_1679	1.012e-115	377.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1IP8P@117747|Sphingobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HKD3_k127_7403639_10	700598.Niako_1564	2.119e-124	412.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1INW8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
HKD3_k127_7403639_14	1267211.KI669560_gene1480	4.333e-109	368.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1IPU4@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
HKD3_k127_7403639_24	925409.KI911562_gene1797	2.966e-62	224.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1IQKS@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_7403639_6	1123248.KB893385_gene4842	2.149e-138	470.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1IPP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD3_k127_7403639_19	925409.KI911562_gene1795	6.455e-90	308.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1IPMS@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
HKD3_k127_7403639_9	929556.Solca_4228	5.782e-126	417.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1IQ33@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HKD3_k127_7403639_1	1267211.KI669560_gene1967	0.0	1064.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HKD3_k127_7403639_15	925409.KI911562_gene2089	2.429e-98	323.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1IRGC@117747|Sphingobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HKD3_k127_7403639_33	700598.Niako_2182	4.28e-25	105.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HKD3_k127_7403639_27	925409.KI911562_gene2091	7.276e-57	199.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1ISA4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD3_k127_7403639_2	1267211.KI669560_gene1963	1.9e-282	872.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1IQUN@117747|Sphingobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD3_k127_7403639_31	1120965.AUBV01000008_gene1997	1.954e-36	143.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,47R71@768503|Cytophagia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
HKD3_k127_7403639_32	925409.KI911562_gene2280	2.448e-29	122.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD3_k127_7403639_23	485918.Cpin_6220	1.827e-64	222.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1ISFT@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HKD3_k127_7403639_4	700598.Niako_2175	3.654e-146	474.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HKD3_k127_7403639_3	925409.KI911562_gene2283	8.632e-269	850.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD3_k127_7403639_21	485918.Cpin_6212	4.6e-73	249.0	COG1666@1|root,COG1666@2|Bacteria,4NMBZ@976|Bacteroidetes,1IRSS@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
HKD3_k127_7403639_30	485918.Cpin_6211	9.223e-41	151.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ITGS@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HKD3_k127_7403639_17	925409.KI911562_gene2202	1.227e-91	314.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1IP3D@117747|Sphingobacteriia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
HKD3_k127_7403639_16	700598.Niako_2168	1.385e-92	311.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1IPGF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HKD3_k127_7403639_37	1137281.D778_00609	3.083e-17	87.0	COG5592@1|root,COG5592@2|Bacteria,4NP8M@976|Bacteroidetes,1I24Y@117743|Flavobacteriia	976|Bacteroidetes	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_7403639_18	1124780.ANNU01000059_gene878	1.551e-91	312.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HKD3_k127_7403639_35	1122605.KB893643_gene891	4.666e-24	116.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_7403639_0	925409.KI911562_gene2407	0.0	1331.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IQJH@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD3_k127_7403639_26	1122605.KB893631_gene3903	2.286e-59	222.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	BatD,TPR_16,TPR_2,TPR_6,TPR_8
HKD3_k127_7403639_8	1123248.KB893325_gene1178	6.39e-132	428.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1IQZS@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
HKD3_k127_7403639_7	700598.Niako_3925	1.732e-135	438.0	COG0226@1|root,COG0226@2|Bacteria,4PKPM@976|Bacteroidetes,1J0PW@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD3_k127_7403639_28	700598.Niako_5176	4.554e-52	190.0	COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,SprB
HKD3_k127_7412311_3	925409.KI911562_gene802	1.843e-81	279.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes	976|Bacteroidetes	H	Uroporphyrin-III C-methyltransferase	cysG	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,NAD_binding_7,Porphobil_deam,TP_methylase
HKD3_k127_7412311_0	700598.Niako_6977	9.842e-199	626.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1IQ1H@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
HKD3_k127_7412311_1	925409.KI911562_gene806	1.899e-168	531.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1INWY@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HKD3_k127_7412311_2	925409.KI911562_gene807	1.023e-98	327.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1IQ9Q@117747|Sphingobacteriia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HKD3_k127_7412311_4	1123276.KB893245_gene1360	5.569e-10	61.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,47M8Z@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_7413214_0	925409.KI911562_gene237	3.132e-235	733.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1IQ95@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase, family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_7413214_1	1408813.AYMG01000014_gene1509	3.651e-226	714.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1IQD0@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD3_k127_7413214_2	1122605.KB893648_gene3597	1.215e-86	287.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1IRJ7@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HKD3_k127_7413214_3	1267211.KI669560_gene1313	5.442e-72	245.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1ISHA@117747|Sphingobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HKD3_k127_7413214_4	1122179.KB890436_gene1406	5.363e-63	235.0	COG1836@1|root,COG1836@2|Bacteria,4NPN7@976|Bacteroidetes,1IUFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
HKD3_k127_7413214_5	313606.M23134_06811	6.678e-13	78.0	298PG@1|root,2ZVTY@2|Bacteria,4NP4F@976|Bacteroidetes,47PR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7420041_1	700598.Niako_0358	9.939e-97	319.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1INY5@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
HKD3_k127_7420041_2	1123248.KB893316_gene4543	1.097e-88	296.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1IQIF@117747|Sphingobacteriia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD3_k127_7420041_0	1123248.KB893316_gene4542	2.699e-197	625.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1IQIH@117747|Sphingobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD3_k127_7441735_3	700598.Niako_0114	2.211e-138	450.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
HKD3_k127_7441735_4	929713.NIASO_19640	9.06e-106	353.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1IRCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
HKD3_k127_7441735_2	468059.AUHA01000004_gene2062	4.246e-234	731.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1IPB8@117747|Sphingobacteriia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HKD3_k127_7441735_1	925409.KI911562_gene1981	8.803e-254	790.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1IPJB@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HKD3_k127_7441735_0	925409.KI911562_gene1982	0.0	2474.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1IP8F@117747|Sphingobacteriia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD3_k127_7441735_5	925409.KI911562_gene550	2.351e-87	290.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1INNU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
HKD3_k127_7447376_3	1121904.ARBP01000025_gene6108	2.946e-89	299.0	COG1874@1|root,COG1874@2|Bacteria,4NINF@976|Bacteroidetes,47NCF@768503|Cytophagia	976|Bacteroidetes	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
HKD3_k127_7447376_0	485918.Cpin_1483	4.309e-195	619.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,1IPR6@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
HKD3_k127_7447376_2	926566.Terro_1765	1.433e-124	422.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,DUF1565,Glyco_hydro_10
HKD3_k127_7447376_1	1121904.ARBP01000025_gene6117	8.893e-170	551.0	2DBBA@1|root,2Z86Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7451329_0	925409.KI911562_gene2863	0.0	1124.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IWX4@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD3_k127_7451329_1	1121285.AUFK01000001_gene1990	2.364e-62	222.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia,3ZQZJ@59732|Chryseobacterium	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
HKD3_k127_7451329_2	485918.Cpin_1878	2.656e-34	137.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1ITQK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7451329_3	1122605.KB893630_gene3980	7.511e-30	120.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1IP76@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_7460107_7	1178825.ALIH01000006_gene1459	1.138e-14	82.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
HKD3_k127_7460107_5	700598.Niako_7350	2.957e-37	146.0	COG4232@1|root,COG4232@2|Bacteria,4NQID@976|Bacteroidetes,1ISZ1@117747|Sphingobacteriia	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
HKD3_k127_7460107_1	925409.KI911562_gene1473	3.585e-117	380.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HKD3_k127_7460107_6	1123248.KB893324_gene1742	3.953e-28	126.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7460107_0	700598.Niako_7347	8.197e-125	417.0	2BV6Z@1|root,32QKE@2|Bacteria,4PCAH@976|Bacteroidetes,1IZE7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7460107_4	643867.Ftrac_3795	1.631e-56	208.0	COG1216@1|root,COG1216@2|Bacteria,4NKAZ@976|Bacteroidetes,47SJI@768503|Cytophagia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_7460107_2	925409.KI911562_gene2003	3.77e-98	341.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1IP8T@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_7460107_3	485918.Cpin_4706	9.268e-90	302.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1IV69@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
HKD3_k127_7472284_7	1454007.JAUG01000018_gene1549	4.947e-11	66.0	2EUHG@1|root,33MZM@2|Bacteria,4NZ9U@976|Bacteroidetes,1IZZA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7472284_0	925409.KI911562_gene757	1.642e-230	727.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IW1A@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HKD3_k127_7472284_5	1123248.KB893348_gene258	1.653e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_7472284_4	700598.Niako_6665	1.802e-69	246.0	28NPZ@1|root,2ZBPQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_7472284_3	700598.Niako_5784	2.596e-99	339.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1IS1E@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7472284_1	1185876.BN8_06159	1.535e-217	685.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,47KFD@768503|Cytophagia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HKD3_k127_7472284_2	1123248.KB893331_gene3766	3.568e-165	525.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,1INVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD3_k127_747624_1	1122605.KB893646_gene227	4.579e-106	351.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD3_k127_747624_3	700598.Niako_6937	6.024e-25	106.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1IUJM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
HKD3_k127_747624_2	700598.Niako_6938	1.73e-74	261.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1INNN@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD3_k127_747624_0	700598.Niako_6939	9.593e-123	396.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
HKD3_k127_7499765_5	700598.Niako_5724	5.431e-43	158.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HKD3_k127_7499765_1	925409.KI911562_gene1430	4.278e-225	703.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_7499765_2	331678.Cphamn1_1901	8.58e-144	466.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
HKD3_k127_7499765_0	1123248.KB893314_gene3644	1.491e-251	796.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQZ4@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7499765_3	1267211.KI669560_gene2733	7.873e-106	351.0	COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_7499765_6	592029.DDD_1829	1.245e-24	119.0	COG4886@1|root,COG4886@2|Bacteria,4NR6Y@976|Bacteroidetes,1I2WF@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Receptor L domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,LRR_5,Recep_L_domain
HKD3_k127_7499765_7	1121887.AUDK01000016_gene1899	3.521e-07	63.0	COG1082@1|root,COG3656@1|root,COG1082@2|Bacteria,COG3656@2|Bacteria,4PNNZ@976|Bacteroidetes,1I4RS@117743|Flavobacteriia,2P0TF@237|Flavobacterium	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
HKD3_k127_7499765_4	760192.Halhy_0613	2.494e-72	250.0	2E0SZ@1|root,32WAT@2|Bacteria,4NIDB@976|Bacteroidetes,1IXSM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_7508573_0	700598.Niako_6288	0.0	1115.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1INSY@117747|Sphingobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HKD3_k127_7508573_3	1385935.N836_30080	4.259e-07	64.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
HKD3_k127_7508573_2	313595.P700755_001235	1.16e-146	506.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NIFD@976|Bacteroidetes,1I1QH@117743|Flavobacteriia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
HKD3_k127_7508573_1	485918.Cpin_3437	2.616e-153	524.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NH20@976|Bacteroidetes,1IQXJ@117747|Sphingobacteriia	976|Bacteroidetes	B	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
HKD3_k127_7527552_2	1123248.KB893348_gene125	4.292e-90	301.0	COG0546@1|root,COG0546@2|Bacteria,4PM7Q@976|Bacteroidetes,1J0KR@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HKD3_k127_7527552_3	1267211.KI669560_gene242	5.344e-85	287.0	COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_7527552_1	700598.Niako_5743	1.415e-95	327.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes,1IPAQ@117747|Sphingobacteriia	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD3_k127_7527552_0	485918.Cpin_0500	3.448e-130	425.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1IQ9R@117747|Sphingobacteriia	976|Bacteroidetes	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD3_k127_7527552_4	1341181.FLJC2902T_06500	3.078e-60	222.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IG7Z@117743|Flavobacteriia,2NXGA@237|Flavobacterium	976|Bacteroidetes	M	Male sterility protein	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
HKD3_k127_7527552_5	1239962.C943_04601	1.089e-40	162.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,47PBG@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HKD3_k127_7527552_6	1121904.ARBP01000003_gene6432	8.974e-05	52.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,47PA0@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD3_k127_7527552_7	1226325.HMPREF1548_04303	0.0002564	48.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,36N1H@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HKD3_k127_7532071_0	1267211.KI669560_gene2464	1.854e-95	318.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_7532071_3	1380384.JADN01000003_gene605	1.093e-47	176.0	COG1680@1|root,COG1680@2|Bacteria,4NQF7@976|Bacteroidetes,1I2XA@117743|Flavobacteriia	976|Bacteroidetes	V	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_7532071_2	1123276.KB893255_gene1880	6.122e-57	201.0	COG0346@1|root,COG0346@2|Bacteria,4NQCJ@976|Bacteroidetes,47QR5@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_7532071_1	743722.Sph21_3230	4.466e-94	315.0	COG0705@1|root,COG0705@2|Bacteria,4NJG9@976|Bacteroidetes,1J16X@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_7542290_2	1123248.KB893329_gene4482	1.431e-114	375.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1INNA@117747|Sphingobacteriia	976|Bacteroidetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD3_k127_7542290_3	700598.Niako_7317	7.033e-26	109.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,1ITPF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7542290_0	1123248.KB893329_gene4484	1.476e-245	777.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD3_k127_7542290_1	700598.Niako_7319	8.736e-182	576.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_7575295_0	1123248.KB893319_gene4061	8.23e-245	771.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
HKD3_k127_7575295_2	1267211.KI669560_gene865	1.681e-212	674.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IQIN@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
HKD3_k127_7575295_1	1267211.KI669560_gene866	5.485e-223	707.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1IPWT@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD3_k127_7575295_3	1121481.AUAS01000006_gene651	4.842e-168	555.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,47XXA@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7575295_8	926549.KI421517_gene2403	1.03e-22	105.0	29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,47RB5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7575295_9	1538644.KO02_17200	1.174e-20	100.0	COG3637@1|root,COG3637@2|Bacteria,4NRZA@976|Bacteroidetes,1ISQI@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD3_k127_7575295_6	1279009.ADICEAN_00224	1.179e-79	274.0	COG0008@1|root,COG0008@2|Bacteria,4NP0Y@976|Bacteroidetes,47Q0Q@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HKD3_k127_7575295_4	929562.Emtol_2445	2.315e-115	381.0	COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,47Q55@768503|Cytophagia	976|Bacteroidetes	G	Glyco_18	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
HKD3_k127_7575295_7	378806.STAUR_4648	1.324e-43	166.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,42UCW@68525|delta/epsilon subdivisions,2WQWQ@28221|Deltaproteobacteria,2YV6G@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
HKD3_k127_7575295_5	1267211.KI669560_gene942	2.459e-115	380.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1INNI@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_7584474_1	925409.KI911562_gene2687	6.84e-114	368.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1IPD0@117747|Sphingobacteriia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD3_k127_7584474_2	762903.Pedsa_1389	1.619e-17	90.0	2E5XB@1|root,330M9@2|Bacteria,4NW0P@976|Bacteroidetes,1IYTT@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4251)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4251
HKD3_k127_7584474_0	1267211.KI669560_gene1821	0.0	1388.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD3_k127_7589520_1	700598.Niako_7005	3.647e-102	338.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1IYWB@117747|Sphingobacteriia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
HKD3_k127_7589520_2	925409.KI911562_gene255	1.464e-83	284.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD3_k127_7589520_3	1033732.CAHI01000027_gene621	2.485e-40	153.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,2FU3Q@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7589520_0	1123248.KB893386_gene1959	3.303e-173	550.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_7589520_4	1121912.AUHD01000015_gene1104	0.0007284	46.0	COG3637@1|root,COG3637@2|Bacteria,4NPV9@976|Bacteroidetes,1I47X@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD3_k127_7621721_6	1267211.KI669560_gene743	4.705e-135	438.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1IWHK@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD3_k127_7621721_11	700598.Niako_6052	1.91e-51	189.0	COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,1IYNI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
HKD3_k127_7621721_5	700598.Niako_6051	2.123e-146	468.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
HKD3_k127_7621721_14	1168034.FH5T_20570	2.332e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,4PH90@976|Bacteroidetes,2FT4B@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7621721_4	1123248.KB893331_gene3804	1.024e-159	522.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1IPQ3@117747|Sphingobacteriia	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
HKD3_k127_7621721_3	1086011.HJ01_01311	8.91e-232	725.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia,2NSEU@237|Flavobacterium	976|Bacteroidetes	G	Major Facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
HKD3_k127_7621721_7	1267211.KI669560_gene1030	1.134e-132	430.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,1IUE3@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HKD3_k127_7621721_1	1267211.KI669560_gene1029	1.424e-286	892.0	COG0366@1|root,COG0366@2|Bacteria,4NI8U@976|Bacteroidetes,1IUZK@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
HKD3_k127_7621721_2	1121889.AUDM01000016_gene2080	1.978e-272	861.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1HY05@117743|Flavobacteriia,2NSRK@237|Flavobacterium	976|Bacteroidetes	G	Alpha-glucosidase	-	-	3.2.1.20,3.2.1.3	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01790,R01791,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31,GH97	-	GH97_C,GH97_N,Glyco_hydro_97
HKD3_k127_7621721_9	700598.Niako_6029	3.17e-125	404.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD3_k127_7621721_12	925409.KI911562_gene478	1.48e-40	152.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1IYVW@117747|Sphingobacteriia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_7621721_13	925409.KI911562_gene477	1.048e-33	133.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1IU5M@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
HKD3_k127_7621721_8	925409.KI911562_gene476	8.862e-129	415.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1INQC@117747|Sphingobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD3_k127_7621721_10	485918.Cpin_0677	7.047e-69	239.0	COG1187@1|root,COG1187@2|Bacteria,4NM4U@976|Bacteroidetes,1IY6P@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HKD3_k127_7621721_0	700598.Niako_6538	0.0	1069.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_7650896_2	1267211.KI669560_gene1999	5.666e-209	667.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IX43@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
HKD3_k127_7650896_4	926550.CLDAP_06890	6.532e-20	94.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	ste14	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
HKD3_k127_7650896_1	700598.Niako_2921	9.194e-214	666.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1INMN@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
HKD3_k127_7650896_0	1123248.KB893337_gene2456	9.588e-259	806.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1IQK5@117747|Sphingobacteriia	976|Bacteroidetes	H	Sigma-54 interaction domain	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
HKD3_k127_7650896_3	700598.Niako_0340	4.873e-55	196.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,1IQHC@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3781 membrane protein	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
HKD3_k127_766906_0	1267211.KI669560_gene83	3.401e-224	715.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IPUE@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HKD3_k127_766906_1	1123248.KB893321_gene501	7.711e-148	484.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1IQJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Outer membrane cobalamin receptor protein	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
HKD3_k127_7703750_1	1506583.JQJY01000008_gene4049	1.518e-59	215.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,1HX95@117743|Flavobacteriia,2NTHP@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD3_k127_7703750_0	700598.Niako_6861	2.269e-89	298.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_772155_6	700598.Niako_2982	4.948e-118	414.0	COG3291@1|root,COG3291@2|Bacteria,4P4YJ@976|Bacteroidetes	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
HKD3_k127_772155_9	525257.HMPREF0204_13883	5.914e-52	188.0	COG2318@1|root,COG2318@2|Bacteria,4NNRD@976|Bacteroidetes,1I4R2@117743|Flavobacteriia,3ZRAI@59732|Chryseobacterium	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
HKD3_k127_772155_8	1121904.ARBP01000005_gene4474	3.945e-59	219.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_772155_5	1121373.KB903637_gene946	1.475e-125	410.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,47JG3@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
HKD3_k127_772155_1	1239962.C943_00093	2.166e-184	592.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,47KT5@768503|Cytophagia	976|Bacteroidetes	U	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
HKD3_k127_772155_7	1202532.FF52_18215	6.212e-88	299.0	COG2067@1|root,COG2067@2|Bacteria,4NQHN@976|Bacteroidetes,1I6SN@117743|Flavobacteriia,2NVGV@237|Flavobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_772155_4	688270.Celal_4232	3.9e-133	436.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes,1I2DH@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
HKD3_k127_772155_3	1492737.FEM08_01140	2.534e-162	522.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,1HWT3@117743|Flavobacteriia,2NSBP@237|Flavobacterium	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
HKD3_k127_772155_2	1239962.C943_00987	3.719e-175	554.0	COG0252@1|root,COG0252@2|Bacteria,4NFKG@976|Bacteroidetes,47MY9@768503|Cytophagia	976|Bacteroidetes	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD3_k127_772155_0	1550091.JROE01000002_gene715	9.493e-240	750.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,1IPGE@117747|Sphingobacteriia	976|Bacteroidetes	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD3_k127_772155_11	908612.HMPREF9720_1877	3.992e-20	98.0	COG3047@1|root,COG3047@2|Bacteria,4NP9X@976|Bacteroidetes,2FMHB@200643|Bacteroidia	976|Bacteroidetes	M	COG NOG27406 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_772155_10	1349822.NSB1T_09490	9.359e-25	110.0	28N4A@1|root,2ZB9T@2|Bacteria,4NKZG@976|Bacteroidetes,2FP6K@200643|Bacteroidia,22XPK@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
HKD3_k127_7727911_22	1122621.ATZA01000001_gene1954	1.411e-09	58.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1IPCE@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD3_k127_7727911_6	925409.KI911562_gene39	6.671e-176	562.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1INV5@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
HKD3_k127_7727911_17	925409.KI911562_gene38	3.256e-45	168.0	COG3254@1|root,COG3254@2|Bacteria,4NQAA@976|Bacteroidetes,1ISWR@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
HKD3_k127_7727911_13	925409.KI911562_gene35	1.344e-107	355.0	COG3618@1|root,COG3618@2|Bacteria,4NFGB@976|Bacteroidetes,1INSJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
HKD3_k127_7727911_9	1123277.KB893217_gene4603	1.675e-122	397.0	COG1028@1|root,COG1028@2|Bacteria,4NH6R@976|Bacteroidetes,47KYG@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K18333	ko00051,ko01120,map00051,map01120	-	R08926	RC00066	ko00000,ko00001	-	-	-	adh_short_C2
HKD3_k127_7727911_7	700598.Niako_5277	1.189e-165	528.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1IPZM@117747|Sphingobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HKD3_k127_7727911_11	700598.Niako_5275	8.969e-120	391.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1IP3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
HKD3_k127_7727911_12	925409.KI911562_gene2995	3.09e-108	355.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,4NDUW@976|Bacteroidetes,1IQ7T@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
HKD3_k127_7727911_2	1267211.KI669560_gene2373	3.214e-204	642.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1INNG@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD3_k127_7727911_8	1267211.KI669560_gene2367	6.258e-150	476.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_7727911_18	929713.NIASO_12035	5.18e-38	147.0	COG4748@1|root,COG4748@2|Bacteria,4PN76@976|Bacteroidetes,1J0M4@117747|Sphingobacteriia	976|Bacteroidetes	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
HKD3_k127_7727911_1	1267211.KI669560_gene2369	5.652e-265	820.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD3_k127_7727911_21	1121957.ATVL01000008_gene4697	8.21e-10	62.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes,47SN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7727911_14	1123248.KB893386_gene1870	1.145e-88	297.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,1INSK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
HKD3_k127_7727911_10	1267211.KI669560_gene2251	7.264e-122	397.0	COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1IPYJ@117747|Sphingobacteriia	976|Bacteroidetes	F	GMP synthase-glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
HKD3_k127_7727911_0	929562.Emtol_2640	0.0	1262.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,47YFD@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7727911_4	761193.Runsl_1110	1.416e-182	584.0	COG0521@1|root,COG0521@2|Bacteria,4NHV5@976|Bacteroidetes,47MJ0@768503|Cytophagia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
HKD3_k127_7727911_16	102129.Lepto7375DRAFT_1962	5.519e-54	199.0	COG0500@1|root,COG0500@2|Bacteria,1G4D6@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
HKD3_k127_7727911_3	1123248.KB893330_gene403	6.219e-198	621.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,1IRMY@117747|Sphingobacteriia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
HKD3_k127_7727911_5	1267211.KI669560_gene2092	8.12e-177	558.0	COG0189@1|root,COG0189@2|Bacteria,4NFK1@976|Bacteroidetes,1IR39@117747|Sphingobacteriia	976|Bacteroidetes	HJ	Glutathione synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7727911_15	925409.KI911562_gene2972	2.673e-64	221.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1IP9F@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
HKD3_k127_7743764_1	925409.KI911562_gene2410	1.272e-226	715.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HKD3_k127_7743764_5	925409.KI911562_gene2411	1.39e-132	432.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1IQ8A@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
HKD3_k127_7743764_15	1250005.PHEL85_3194	3.739e-26	116.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia,3VWKB@52959|Polaribacter	976|Bacteroidetes	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HKD3_k127_7743764_10	1267211.KI669560_gene1778	3.359e-78	267.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1ISB1@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA methyltransferase, RsmD	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD3_k127_7743764_0	925409.KI911562_gene2039	0.0	1049.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HKD3_k127_7743764_11	925409.KI911562_gene2345	5.157e-76	258.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD3_k127_7743764_8	1267211.KI669560_gene2098	1.765e-105	354.0	COG3268@1|root,COG3268@2|Bacteria,4NHDM@976|Bacteroidetes,1IRKS@117747|Sphingobacteriia	976|Bacteroidetes	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
HKD3_k127_7743764_3	1123248.KB893314_gene3477	1.735e-150	489.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1IPQM@117747|Sphingobacteriia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HKD3_k127_7743764_7	1121875.KB907548_gene1528	3.402e-111	377.0	COG2355@1|root,COG2355@2|Bacteria,4NI3V@976|Bacteroidetes,1I0XS@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
HKD3_k127_7743764_12	1227739.Hsw_4227	1.166e-44	171.0	COG2935@1|root,COG2935@2|Bacteria,4NGKN@976|Bacteroidetes,47PCC@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the R-transferase family	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
HKD3_k127_7743764_9	1270196.JCKI01000004_gene1179	8.215e-105	348.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,1IR8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
HKD3_k127_7743764_14	1123248.KB893321_gene522	2.762e-35	139.0	COG4270@1|root,COG4270@2|Bacteria,4NVXH@976|Bacteroidetes,1IZMV@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD3_k127_7743764_6	483219.LILAB_29395	4.156e-122	403.0	COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria,42ZA2@68525|delta/epsilon subdivisions,2X2MN@28221|Deltaproteobacteria,2YUIW@29|Myxococcales	28221|Deltaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
HKD3_k127_7743764_2	1189612.A33Q_0627	3.864e-151	485.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7743764_4	1189612.A33Q_0628	4.297e-149	482.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipoxygenase
HKD3_k127_7783446_8	1123248.KB893314_gene3600	2.175e-41	156.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_7783446_7	1120968.AUBX01000015_gene3687	2.66e-77	266.0	COG0605@1|root,COG0605@2|Bacteria,4NK61@976|Bacteroidetes,47N71@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD3_k127_7783446_10	925409.KI911562_gene235	7.045e-34	135.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
HKD3_k127_7783446_5	700598.Niako_7029	2.285e-123	404.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1IP0G@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD3_k127_7783446_6	929713.NIASO_07155	3.555e-96	319.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1IXCK@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD3_k127_7783446_11	485918.Cpin_7286	6.868e-19	93.0	2AFPJ@1|root,315RB@2|Bacteria,4PJWT@976|Bacteroidetes,1IUP5@117747|Sphingobacteriia	976|Bacteroidetes	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
HKD3_k127_7783446_2	700598.Niako_0151	3.626e-188	595.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1INTB@117747|Sphingobacteriia	976|Bacteroidetes	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_7783446_4	925409.KI911562_gene2707	2.495e-149	483.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,1IPI3@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
HKD3_k127_7783446_9	929562.Emtol_2436	5.177e-35	135.0	COG2350@1|root,COG2350@2|Bacteria,4NT2N@976|Bacteroidetes,47RBM@768503|Cytophagia	976|Bacteroidetes	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
HKD3_k127_7783446_1	485918.Cpin_5572	1.995e-189	594.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1INXZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
HKD3_k127_7783446_0	1279009.ADICEAN_03358	4.424e-210	670.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
HKD3_k127_7783446_3	700598.Niako_2576	1.041e-168	539.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1INQK@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	aldH	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD3_k127_7937512_1	1089547.KB913013_gene4669	2.253e-260	828.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_7937512_0	1089547.KB913013_gene4668	0.0	1298.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_7937512_3	1089547.KB913013_gene4667	8.233e-193	615.0	COG3637@1|root,COG3637@2|Bacteria,4PMFW@976|Bacteroidetes	976|Bacteroidetes	M	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_7937512_2	1120968.AUBX01000017_gene1929	3.182e-200	634.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,47P1H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_7937512_4	1089547.KB913013_gene4665	3.815e-180	580.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2
HKD3_k127_7937512_5	504472.Slin_6434	1.669e-94	317.0	COG2273@1|root,COG2273@2|Bacteria,4NF91@976|Bacteroidetes,47MDE@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Glyco_hydro_16,Glyco_hydro_43
HKD3_k127_7937512_7	471854.Dfer_3347	2.166e-21	110.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Gram_pos_anchor,LTD,SLH
HKD3_k127_7937512_6	1089547.KB913013_gene4663	1.545e-66	252.0	COG1501@1|root,COG1595@1|root,COG1501@2|Bacteria,COG1595@2|Bacteria,4NHIK@976|Bacteroidetes,47WW7@768503|Cytophagia	976|Bacteroidetes	K	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_cc,Laminin_G_3
HKD3_k127_7937512_8	762903.Pedsa_0698	1.862e-18	90.0	COG3391@1|root,COG3391@2|Bacteria,4NVUM@976|Bacteroidetes	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8019140_9	762903.Pedsa_1112	2.477e-22	96.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1INN8@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
HKD3_k127_8019140_1	1492737.FEM08_10520	1.081e-246	768.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1HZDG@117743|Flavobacteriia,2NUCI@237|Flavobacterium	976|Bacteroidetes	C	4Fe-4S ferredoxin	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
HKD3_k127_8019140_7	1492737.FEM08_10530	2.351e-57	209.0	COG1556@1|root,COG1556@2|Bacteria,4NQSF@976|Bacteroidetes,1I4SQ@117743|Flavobacteriia,2NSAM@237|Flavobacterium	976|Bacteroidetes	S	ACR, YkgG family COG1556	lutC	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
HKD3_k127_8019140_5	1434325.AZQN01000008_gene2918	2.102e-70	248.0	COG1409@1|root,COG1409@2|Bacteria,4NN8T@976|Bacteroidetes,47PD0@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_8019140_2	649349.Lbys_2943	6.274e-242	752.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,47K9A@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
HKD3_k127_8019140_0	700598.Niako_4610	0.0	1014.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HKD3_k127_8019140_3	1123248.KB893326_gene1441	1.309e-135	439.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_8019140_8	468059.AUHA01000005_gene2445	8.982e-28	116.0	COG2149@1|root,COG2149@2|Bacteria,4NW0X@976|Bacteroidetes,1IZG7@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
HKD3_k127_8019140_4	1123248.KB893326_gene1438	1.619e-86	293.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1IS9I@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_8019140_6	172045.KS04_02100	6.635e-61	212.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia,34PV2@308865|Elizabethkingia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_809233_2	485918.Cpin_3594	4.516e-174	548.0	COG0457@1|root,COG0457@2|Bacteria,4NIBU@976|Bacteroidetes,1IQKQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_16,TPR_6,TPR_8
HKD3_k127_809233_4	700598.Niako_3556	5.541e-94	317.0	COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,4PKXD@976|Bacteroidetes,1J0T3@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_AraC
HKD3_k127_809233_1	485918.Cpin_3592	1.049e-177	571.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1IP67@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	ko:K02100,ko:K03444,ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1,2.A.1.1.2,2.A.1.1.3	-	-	Sugar_tr
HKD3_k127_809233_0	376686.Fjoh_3805	3.133e-263	823.0	COG2361@1|root,COG2361@2|Bacteria,4PKES@976|Bacteroidetes,1IJUR@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
HKD3_k127_809233_3	1492737.FEM08_18140	3.424e-171	541.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HZNT@117743|Flavobacteriia,2P027@237|Flavobacterium	976|Bacteroidetes	G	PRINTS Glycosyl hydrolase family 29 signature	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
HKD3_k127_8116162_0	929562.Emtol_3518	7.657e-200	638.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47MZ7@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD3_k127_8116162_3	700598.Niako_5674	2.072e-85	293.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1IP6P@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
HKD3_k127_8116162_6	1122605.KB893625_gene2115	6.32e-08	63.0	COG3088@1|root,COG3088@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
HKD3_k127_8116162_2	700598.Niako_5676	7.129e-91	308.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1IRJS@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HKD3_k127_8116162_1	1123248.KB893348_gene312	4.708e-136	440.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD3_k127_8116162_5	925409.KI911562_gene283	4.922e-56	207.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1IT51@117747|Sphingobacteriia	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_8116162_4	1267211.KI669560_gene2548	1.92e-82	280.0	COG2859@1|root,COG2859@2|Bacteria,4NI76@976|Bacteroidetes,1IS8C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
HKD3_k127_8123718_0	1123248.KB893322_gene578	1.725e-224	701.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1IQZ1@117747|Sphingobacteriia	976|Bacteroidetes	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HKD3_k127_8123718_6	1121904.ARBP01000032_gene1996	6.211e-10	71.0	2DR9Y@1|root,33AUY@2|Bacteria	2|Bacteria	L	HNH endonuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
HKD3_k127_8123718_5	1121899.Q764_01850	1.129e-29	132.0	2AFQQ@1|root,315SK@2|Bacteria,4NS2X@976|Bacteroidetes,1I3KK@117743|Flavobacteriia,2NU14@237|Flavobacterium	976|Bacteroidetes	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
HKD3_k127_8123718_3	1122621.ATZA01000001_gene2029	7.853e-176	591.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1IR6V@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	recB	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HKD3_k127_8123718_2	391596.PBAL39_12232	3.497e-183	607.0	COG2887@1|root,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1J0H9@117747|Sphingobacteriia	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
HKD3_k127_8123718_1	925409.KI911562_gene419	8.956e-224	697.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_8123718_4	929562.Emtol_0667	6.35e-129	421.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47K8N@768503|Cytophagia	976|Bacteroidetes	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
HKD3_k127_831131_0	925409.KI911562_gene42	4.574e-164	523.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HKD3_k127_831131_2	316274.Haur_1457	4.325e-56	204.0	COG2135@1|root,COG2135@2|Bacteria,2G74X@200795|Chloroflexi,377BN@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HKD3_k127_831131_1	700598.Niako_5142	6.774e-60	210.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HKD3_k127_83118_3	402612.FP1017	4.337e-124	422.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,4PM7A@976|Bacteroidetes,1IJK9@117743|Flavobacteriia,2P0PF@237|Flavobacterium	976|Bacteroidetes	T	Heme NO binding associated	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HNOBA,HisKA,PAS_3,PAS_9,Response_reg
HKD3_k127_83118_5	1086011.HJ01_00981	3.554e-83	279.0	COG1060@1|root,COG1060@2|Bacteria,4PDXS@976|Bacteroidetes,1ICYV@117743|Flavobacteriia,2NW7K@237|Flavobacterium	976|Bacteroidetes	H	Haem-NO-binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
HKD3_k127_83118_0	1166018.FAES_4763	1.388e-201	641.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47NKU@768503|Cytophagia	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
HKD3_k127_83118_6	1166018.FAES_4762	5.239e-80	279.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,47THI@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase, family 4	rfe	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
HKD3_k127_83118_1	1166018.FAES_4761	1.691e-188	595.0	COG0438@1|root,COG0438@2|Bacteria,4NEJ6@976|Bacteroidetes,47JTJ@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glycos_transf_1
HKD3_k127_83118_4	1166018.FAES_4758	7.137e-118	389.0	COG0438@1|root,COG0438@2|Bacteria,4NIQ3@976|Bacteroidetes,47KMV@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_83118_2	1166018.FAES_4757	6.245e-150	487.0	COG0438@1|root,COG0438@2|Bacteria,4NHUT@976|Bacteroidetes,47P33@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HKD3_k127_8344796_2	1408473.JHXO01000008_gene2847	2.838e-28	123.0	COG3537@1|root,COG3537@2|Bacteria,4NIAX@976|Bacteroidetes,2FQH5@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_8344796_1	153721.MYP_1602	2.059e-185	605.0	COG1472@1|root,COG1472@2|Bacteria,4P1RG@976|Bacteroidetes,47TJ7@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD3_k127_8344796_0	1185876.BN8_04513	2.819e-201	647.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,47JV2@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
HKD3_k127_8353579_0	697281.Mahau_2278	3.195e-230	728.0	COG1874@1|root,COG1874@2|Bacteria,1TT9J@1239|Firmicutes,24CY9@186801|Clostridia,42HX5@68295|Thermoanaerobacterales	186801|Clostridia	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
HKD3_k127_843731_3	700598.Niako_5783	4.589e-36	139.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1IP42@117747|Sphingobacteriia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HKD3_k127_843731_1	700598.Niako_5782	2.676e-135	456.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1IQH4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
HKD3_k127_843731_2	861299.J421_1115	1.984e-58	215.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_843731_4	1120968.AUBX01000011_gene3203	2.238e-20	97.0	COG0406@1|root,COG0406@2|Bacteria,4NQWA@976|Bacteroidetes,47SDA@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HKD3_k127_843731_0	1185876.BN8_04770	3.479e-149	479.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD3_k127_8465696_11	925409.KI911562_gene233	4.802e-97	329.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD3_k127_8465696_22	1267211.KI669560_gene931	2.402e-26	124.0	2E469@1|root,32Z27@2|Bacteria,4P4UV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8465696_15	700598.Niako_7032	6.696e-63	218.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1ISF1@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD3_k127_8465696_7	925409.KI911562_gene231	1.961e-142	456.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_8465696_3	925409.KI911562_gene230	7.033e-230	717.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1INMC@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD3_k127_8465696_14	1123248.KB893314_gene3420	1.874e-72	248.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1IRXR@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD3_k127_8465696_17	700598.Niako_7036	8.197e-60	213.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1ISWU@117747|Sphingobacteriia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HKD3_k127_8465696_8	1120968.AUBX01000018_gene2161	2.967e-125	413.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,47JI6@768503|Cytophagia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD3_k127_8465696_0	700598.Niako_6680	0.0	1114.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,4NER2@976|Bacteroidetes,1IQ4S@117747|Sphingobacteriia	976|Bacteroidetes	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
HKD3_k127_8465696_16	700598.Niako_3733	1.379e-60	217.0	COG0300@1|root,COG0300@2|Bacteria,4NK81@976|Bacteroidetes,1ISB6@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_8465696_10	1124780.ANNU01000036_gene37	2.2e-108	364.0	COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_8465696_12	1267211.KI669560_gene1544	8.829e-95	323.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	MA20_03510	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_8465696_13	1123248.KB893337_gene2490	2.124e-89	302.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1ISM8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Sulfite exporter TauE SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_8465696_2	925409.KI911562_gene2106	3.095e-248	771.0	COG0731@1|root,COG0731@2|Bacteria,4PNUE@976|Bacteroidetes,1J0SJ@117747|Sphingobacteriia	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_8465696_6	1122605.KB893637_gene3159	1.348e-147	476.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD3_k127_8465696_19	1121912.AUHD01000008_gene46	5.63e-43	160.0	COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,1I4WB@117743|Flavobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
HKD3_k127_8465696_5	700598.Niako_2545	1.901e-149	477.0	COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,1J0R0@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_8465696_20	925409.KI911562_gene2210	5.771e-41	156.0	2ADZU@1|root,313SD@2|Bacteria,4PK7E@976|Bacteroidetes,1IUKW@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
HKD3_k127_8465696_4	700598.Niako_2543	1.138e-154	498.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_8465696_18	1123248.KB893323_gene1627	1.264e-49	183.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,1ISBI@117747|Sphingobacteriia	976|Bacteroidetes	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
HKD3_k127_8465696_9	925409.KI911562_gene248	2.113e-118	384.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1IQ54@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HKD3_k127_8465696_1	925409.KI911562_gene249	5.832e-300	936.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IUW9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD3_k127_8465696_23	929562.Emtol_1414	3.083e-16	88.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3,Response_reg
HKD3_k127_8465696_21	420662.Mpe_A0045	1.363e-35	139.0	COG2940@1|root,COG2940@2|Bacteria,1RIQT@1224|Proteobacteria,2VT7F@28216|Betaproteobacteria,1KM5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD3_k127_8473442_0	925409.KI911562_gene746	7.871e-84	292.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
HKD3_k127_8473442_1	925409.KI911562_gene745	1.56e-83	286.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1IXDH@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_8473442_2	925409.KI911562_gene744	1.455e-53	195.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1ITFC@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
HKD3_k127_8490280_2	1297742.A176_02167	1.047e-77	271.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_8490280_0	485918.Cpin_1847	1.808e-229	717.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD3_k127_8490280_1	1267211.KI669560_gene2294	3.263e-170	557.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1IPAV@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_8493874_6	616991.JPOO01000003_gene620	1.059e-38	146.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1HX1B@117743|Flavobacteriia,23FUV@178469|Arenibacter	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD3_k127_8493874_3	925409.KI911562_gene1308	1.799e-55	195.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,1ISAQ@117747|Sphingobacteriia	976|Bacteroidetes	S	MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
HKD3_k127_8493874_2	485918.Cpin_0414	2.656e-70	241.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HKD3_k127_8493874_0	929713.NIASO_00270	2.88e-84	284.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1ISQ4@117747|Sphingobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD3_k127_8493874_1	700598.Niako_5540	2.235e-82	276.0	COG1978@1|root,COG1978@2|Bacteria,4NNSE@976|Bacteroidetes,1IS2T@117747|Sphingobacteriia	976|Bacteroidetes	S	Ribonuclease H-like	-	-	-	ko:K09776	-	-	-	-	ko00000	-	-	-	RNaseH_like
HKD3_k127_8493874_5	925409.KI911562_gene272	2.033e-42	160.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,1ITJY@117747|Sphingobacteriia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
HKD3_k127_8493874_4	1313421.JHBV01000052_gene192	5.992e-54	217.0	COG3209@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5384@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5384@2|Bacteria,4PPW2@976|Bacteroidetes,1J12N@117747|Sphingobacteriia	2|Bacteria	JMU	domain protein	-	-	3.2.1.4	ko:K01179,ko:K19360,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000,ko03036	1.B.40.2	GH5,GH9	-	FIVAR,LRR_5,Phospholip_A2_3
HKD3_k127_8495224_3	700598.Niako_6016	1.314e-38	148.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1IQZP@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
HKD3_k127_8495224_1	760192.Halhy_4831	1.858e-65	256.0	COG2706@1|root,COG3210@1|root,COG3291@1|root,COG5492@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NN8J@976|Bacteroidetes,1IUSR@117747|Sphingobacteriia	976|Bacteroidetes	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD3_k127_8495224_5	1267533.KB906736_gene1440	6.296e-13	83.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,FG-GAP,VCBS
HKD3_k127_8495224_0	700598.Niako_6017	1.316e-95	317.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1INZ4@117747|Sphingobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HKD3_k127_8495224_4	925409.KI911562_gene469	3.807e-21	99.0	2E3Q9@1|root,32YN7@2|Bacteria,4NWH3@976|Bacteroidetes,1IZ69@117747|Sphingobacteriia	976|Bacteroidetes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
HKD3_k127_8495224_2	760192.Halhy_2436	1.527e-51	190.0	COG2010@1|root,COG2010@2|Bacteria,4NX4D@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8496284_3	925409.KI911562_gene1178	1.215e-21	98.0	COG2989@1|root,COG2989@2|Bacteria,4NKTZ@976|Bacteroidetes,1IRHA@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
HKD3_k127_8496284_2	1434325.AZQN01000001_gene556	7.667e-93	311.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,47MU1@768503|Cytophagia	976|Bacteroidetes	T	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
HKD3_k127_8496284_1	485918.Cpin_7081	1.015e-152	494.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1INYT@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8496284_0	925409.KI911562_gene1176	3.124e-206	659.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD3_k127_8496284_4	925409.KI911562_gene277	1.052e-11	66.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_8515423_3	700598.Niako_5269	1.542e-53	190.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HKD3_k127_8515423_1	700598.Niako_6235	8.029e-73	262.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1IU84@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_8515423_0	929562.Emtol_2762	1.177e-73	259.0	COG2755@1|root,COG2755@2|Bacteria,4NHWJ@976|Bacteroidetes,47NGU@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_8515423_2	1434325.AZQN01000008_gene2924	1.35e-62	220.0	COG0662@1|root,COG0662@2|Bacteria,4NNWT@976|Bacteroidetes,47Q0Y@768503|Cytophagia	976|Bacteroidetes	G	PFAM Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
HKD3_k127_8515423_4	1305737.JAFX01000001_gene1982	4.929e-20	94.0	2DZT8@1|root,32VIB@2|Bacteria,4NRNI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8517385_0	1267211.KI669560_gene998	5.245e-95	318.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1IV3Y@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HKD3_k127_8517385_1	485918.Cpin_7185	1.314e-73	252.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1ITKI@117747|Sphingobacteriia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
HKD3_k127_8517385_3	1123248.KB893323_gene1558	1.311e-60	214.0	2B1RZ@1|root,31U7Q@2|Bacteria,4NR0B@976|Bacteroidetes,1IYX1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8565840_0	700598.Niako_6249	5.457e-127	413.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1IQR6@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD3_k127_8565840_1	485918.Cpin_0849	4.193e-110	362.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
HKD3_k127_857275_1	1267211.KI669560_gene1415	7.818e-150	476.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD3_k127_857275_3	925409.KI911562_gene2665	1.061e-84	299.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
HKD3_k127_857275_2	700598.Niako_1526	5.797e-138	442.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1IPR7@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
HKD3_k127_857275_5	925409.KI911562_gene2667	7.952e-79	274.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1IQ34@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HKD3_k127_857275_7	925409.KI911562_gene2668	5.159e-46	169.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,1IT2H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HKD3_k127_857275_4	925409.KI911562_gene2669	6.865e-84	291.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD3_k127_857275_6	700598.Niako_1522	2.454e-63	221.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,1ISYY@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
HKD3_k127_857275_0	925409.KI911562_gene2671	1.966e-229	718.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD3_k127_8573926_2	1123248.KB893326_gene1436	8.309e-43	162.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8
HKD3_k127_8573926_1	1107311.Q767_05060	1.597e-55	205.0	COG1670@1|root,COG1670@2|Bacteria,4NMB7@976|Bacteroidetes,1I271@117743|Flavobacteriia,2P04V@237|Flavobacterium	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_8573926_4	760192.Halhy_0387	1.611e-12	76.0	COG1846@1|root,COG1846@2|Bacteria,4NQ6H@976|Bacteroidetes,1ITZW@117747|Sphingobacteriia	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
HKD3_k127_8573926_0	1267211.KI669560_gene2035	2.568e-317	990.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1ISRU@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_8573926_3	700598.Niako_4420	2.482e-27	114.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1IP6X@117747|Sphingobacteriia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_8581461_7	1122605.KB893634_gene4221	5.751e-28	115.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD3_k127_8581461_8	929713.NIASO_00550	1.044e-14	81.0	COG0526@1|root,COG0526@2|Bacteria,4NY16@976|Bacteroidetes	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_8581461_2	1267211.KI669560_gene2540	6.672e-176	555.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
HKD3_k127_8581461_3	1123248.KB893323_gene1623	1.152e-146	473.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HKD3_k127_8581461_0	1267211.KI669560_gene2542	1.395e-206	649.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_8581461_4	1267211.KI669560_gene2543	1.94e-100	332.0	COG0586@1|root,COG0586@2|Bacteria,4NMPN@976|Bacteroidetes,1IWBE@117747|Sphingobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
HKD3_k127_8581461_1	1120965.AUBV01000013_gene1347	2.667e-197	625.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
HKD3_k127_8581461_5	702450.CUW_2447	1.672e-71	258.0	COG0524@1|root,COG0524@2|Bacteria,1TRRQ@1239|Firmicutes,3VTFQ@526524|Erysipelotrichia	526524|Erysipelotrichia	H	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
HKD3_k127_8581461_6	247490.KSU1_C0449	1.915e-35	151.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
HKD3_k127_8601722_1	700598.Niako_6427	9.735e-60	211.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1IPE9@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
HKD3_k127_8601722_2	153721.MYP_3912	8.162e-50	180.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,47Q8F@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HKD3_k127_8601722_0	1239962.C943_03733	2.48e-61	232.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4P3P6@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8601722_3	376686.Fjoh_3401	4.466e-35	141.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,1I22Y@117743|Flavobacteriia,2NVTZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD3_k127_8601722_4	1121904.ARBP01000018_gene2685	2.219e-13	75.0	2E74W@1|root,331P9@2|Bacteria,4P4VB@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD3_k127_8601853_1	700598.Niako_5083	3.449e-139	457.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1IS75@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41
HKD3_k127_8601853_0	925409.KI911562_gene490	6.356e-164	521.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1IQIA@117747|Sphingobacteriia	976|Bacteroidetes	C	potassium channel beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_8601853_5	929713.NIASO_14905	2.216e-37	151.0	COG3117@1|root,COG3117@2|Bacteria,4NV8G@976|Bacteroidetes,1IU6N@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
HKD3_k127_8601853_2	1123248.KB893348_gene286	7.022e-107	361.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8601853_3	700598.Niako_6548	3.083e-96	320.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1ISYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HKD3_k127_8601853_4	1267211.KI669560_gene718	1.068e-95	315.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD3_k127_8610742_13	485918.Cpin_1239	1.055e-12	69.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1IQNE@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_8610742_4	925409.KI911562_gene1207	1.436e-102	339.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1IR07@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HKD3_k127_8610742_12	1338011.BD94_3341	1.939e-20	97.0	2DSW4@1|root,33HNK@2|Bacteria,4NW6Z@976|Bacteroidetes,1I9R5@117743|Flavobacteriia,34S7X@308865|Elizabethkingia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_8610742_2	1267211.KI669560_gene2802	9.083e-169	536.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1IP2F@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
HKD3_k127_8610742_6	1267211.KI669560_gene2804	1e-75	261.0	29C3H@1|root,32VP8@2|Bacteria,4NXVV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8610742_11	1453500.AT05_11480	5.724e-24	118.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD3_k127_8610742_0	471854.Dfer_4322	0.0	1203.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
HKD3_k127_8610742_5	926562.Oweho_2761	2.781e-83	284.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia,2PARB@246874|Cryomorphaceae	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD3_k127_8610742_3	925409.KI911562_gene259	4.266e-163	523.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_8610742_8	1337936.IJ00_14570	1.179e-62	233.0	COG4995@1|root,COG4995@2|Bacteria,1GDVF@1117|Cyanobacteria,1HTQS@1161|Nostocales	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
HKD3_k127_8610742_1	700598.Niako_6644	0.0	1042.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1IYHV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HKD3_k127_8610742_7	1123248.KB893332_gene2245	1.103e-66	230.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1IS01@117747|Sphingobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD3_k127_8610742_9	700598.Niako_6929	1.214e-47	179.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1ISWH@117747|Sphingobacteriia	976|Bacteroidetes	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HKD3_k127_8610742_10	1123248.KB893385_gene4779	5.255e-37	141.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1ISJU@117747|Sphingobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HKD3_k127_8611877_5	700598.Niako_2576	5.848e-40	151.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1INQK@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	aldH	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD3_k127_8611877_4	504472.Slin_5788	2.07e-55	198.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,47Q23@768503|Cytophagia	976|Bacteroidetes	L	transposase IS200-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD3_k127_8611877_0	760192.Halhy_1214	2.261e-138	446.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1IQRX@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_8611877_2	700598.Niako_5259	5.547e-71	250.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NGHV@976|Bacteroidetes,1IQY1@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
HKD3_k127_8611877_1	1341155.FSS13T_14680	7.631e-92	329.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia,2NUU8@237|Flavobacterium	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4,AhpC-TSA,Redoxin,Thioredoxin_8
HKD3_k127_8611877_3	1341181.FLJC2902T_25480	4.285e-61	216.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1I1AY@117743|Flavobacteriia,2NT7W@237|Flavobacterium	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K20459	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
HKD3_k127_8613566_1	313624.NSP_23270	3.595e-171	543.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria,1HM8T@1161|Nostocales	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
HKD3_k127_8613566_0	485918.Cpin_4009	5.079e-309	962.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1IR7E@117747|Sphingobacteriia	976|Bacteroidetes	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
HKD3_k127_8613566_2	468059.AUHA01000003_gene1520	8.731e-137	453.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1IPI2@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_8613566_3	760192.Halhy_1400	1.08e-120	396.0	COG4242@1|root,COG4242@2|Bacteria,4NIBM@976|Bacteroidetes,1IWK8@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
HKD3_k127_8613566_5	1341155.FSS13T_21560	1.783e-73	263.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HKD3_k127_8613566_4	1239962.C943_03799	3.876e-96	334.0	29X8I@1|root,30IXV@2|Bacteria,4P0MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8626087_2	760192.Halhy_4438	1.511e-54	197.0	COG1834@1|root,COG1834@2|Bacteria,4NFQ7@976|Bacteroidetes,1IPRX@117747|Sphingobacteriia	976|Bacteroidetes	E	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD3_k127_8626087_0	1185876.BN8_01506	0.0	1081.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,47JJS@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD3_k127_8626087_1	468059.AUHA01000004_gene2189	1.909e-93	312.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1IS4K@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_8626087_3	1122605.KB893638_gene3447	1.335e-45	168.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
HKD3_k127_8655737_2	1089547.KB913013_gene4669	2.081e-126	422.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD3_k127_8655737_0	1089547.KB913013_gene4670	1.168e-212	672.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
HKD3_k127_8655737_3	1380600.AUYN01000009_gene1522	3.26e-94	315.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	SASA
HKD3_k127_8655737_4	1166018.FAES_1675	6.878e-91	307.0	COG2273@1|root,COG2273@2|Bacteria,4NF91@976|Bacteroidetes,47MDE@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Glyco_hydro_16,Glyco_hydro_43
HKD3_k127_8655737_1	760192.Halhy_0433	4.251e-151	485.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1IS5G@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
HKD3_k127_8656814_1	1267211.KI669560_gene1365	1.257e-219	687.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HKD3_k127_8656814_5	925409.KI911562_gene2747	1.478e-50	192.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes	976|Bacteroidetes	I	PFAM Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
HKD3_k127_8656814_0	485918.Cpin_0197	0.0	1004.0	COG1297@1|root,COG1297@2|Bacteria,4NEIY@976|Bacteroidetes,1IP8J@117747|Sphingobacteriia	976|Bacteroidetes	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HKD3_k127_8656814_2	886379.AEWI01000010_gene602	5.099e-179	576.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,2FNB6@200643|Bacteroidia,3XJM3@558415|Marinilabiliaceae	976|Bacteroidetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD3_k127_8656814_3	485918.Cpin_0195	1.133e-164	528.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD3_k127_8656814_4	468059.AUHA01000002_gene745	4.376e-149	481.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1IUY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD3_k127_8668888_1	700598.Niako_6983	1.894e-152	494.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,1IQMJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
HKD3_k127_8668888_0	925409.KI911562_gene800	4.169e-251	785.0	COG0155@1|root,COG0155@2|Bacteria,4NENW@976|Bacteroidetes	976|Bacteroidetes	C	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	cysI	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HKD3_k127_8668888_2	1416760.AYMS01000111_gene2811	7.698e-50	182.0	COG0369@1|root,COG0369@2|Bacteria,4NHR8@976|Bacteroidetes,1HY7F@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfite reductase	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1,PepSY_TM
HKD3_k127_8670402_2	543728.Vapar_4365	2.938e-79	272.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2VKKP@28216|Betaproteobacteria,4AD97@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
HKD3_k127_8670402_1	945713.IALB_2618	7.542e-225	705.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD3_k127_8670402_0	1121288.AULL01000011_gene1078	4.799e-242	753.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1I067@117743|Flavobacteriia,3ZNS9@59732|Chryseobacterium	976|Bacteroidetes	E	Beta-eliminating lyase	tpl	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
HKD3_k127_8670402_4	700598.Niako_1615	1.269e-66	240.0	COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,1IQAT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Allophanate hydrolase subunit 2	-	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
HKD3_k127_8670402_6	593117.TGAM_1183	3.254e-44	170.0	COG2049@1|root,arCOG05809@2157|Archaea,2XUMA@28890|Euryarchaeota,242UF@183968|Thermococci	183968|Thermococci	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
HKD3_k127_8670402_5	929713.NIASO_18860	1.233e-49	180.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1ISJI@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HKD3_k127_8670402_7	1122605.KB893644_gene1520	7.704e-42	154.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1ISSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HKD3_k127_8670402_3	1267211.KI669560_gene2483	1.103e-66	230.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1IRUM@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HKD3_k127_8670402_8	1279017.AQYJ01000029_gene3400	1.773e-06	51.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,46C71@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8694639_1	886293.Sinac_0921	8.257e-83	288.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR,BNR_2,CBM_2,RicinB_lectin_2
HKD3_k127_8694639_0	1122605.KB893643_gene522	6.315e-252	784.0	COG3669@1|root,COG3669@2|Bacteria,4NHZ4@976|Bacteroidetes,1IRFU@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,F5_F8_type_C
HKD3_k127_8694639_2	388413.ALPR1_02315	1.384e-48	183.0	2AC8D@1|root,311T2@2|Bacteria,4NXA6@976|Bacteroidetes,47SP0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8724303_2	1121012.AUKX01000052_gene2592	0.0004293	44.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,23HW2@178469|Arenibacter	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD3_k127_8724303_1	1123248.KB893348_gene81	6.034e-87	291.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1IQ2V@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
HKD3_k127_8724303_0	925409.KI911562_gene1107	5.57e-195	614.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
HKD3_k127_8729327_5	762903.Pedsa_2280	1.997e-23	108.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1IU8K@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD3_k127_8729327_4	117187.FVEG_03255T0	1.215e-35	152.0	2CZCX@1|root,2S9RS@2759|Eukaryota,3A9VX@33154|Opisthokonta,3P716@4751|Fungi,3R433@4890|Ascomycota,21PHA@147550|Sordariomycetes	4751|Fungi	E	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Astacin,H_lectin
HKD3_k127_8729327_0	1123248.KB893316_gene4610	6.034e-158	503.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1IYQQ@117747|Sphingobacteriia	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD3_k127_8729327_1	700598.Niako_3669	5.61e-118	392.0	COG1502@1|root,COG1502@2|Bacteria,4P0CZ@976|Bacteroidetes,1J0D9@117747|Sphingobacteriia	976|Bacteroidetes	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HKD3_k127_8729327_2	468059.AUHA01000003_gene1728	9.205e-63	223.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,1IW0G@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
HKD3_k127_8729327_3	1123368.AUIS01000038_gene37	2.282e-61	218.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,1S4YT@1236|Gammaproteobacteria,2ND78@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
HKD3_k127_8729327_7	573064.Mefer_0292	4.155e-15	87.0	arCOG07790@1|root,arCOG07790@2157|Archaea,2Y0S6@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM D-glucuronyl C5-epimerase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	C5-epim_C
HKD3_k127_8729327_6	411154.GFO_1271	3.546e-16	79.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia	976|Bacteroidetes	S	transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD3_k127_8767875_6	1267211.KI669560_gene287	1.947e-18	88.0	COG1286@1|root,COG1286@2|Bacteria,4P9DM@976|Bacteroidetes,1IZI5@117747|Sphingobacteriia	976|Bacteroidetes	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
HKD3_k127_8767875_3	700598.Niako_6586	6.588e-50	186.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1IT3W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HKD3_k127_8767875_4	925409.KI911562_gene892	2.542e-40	154.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1ISTG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein, GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8767875_5	925409.KI911562_gene891	9.58e-23	111.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1ITGA@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_8767875_1	1267211.KI669560_gene309	8.755e-82	278.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1IQZH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
HKD3_k127_8767875_7	1179778.PMM47T1_17385	1.291e-09	64.0	2EQUD@1|root,33IE5@2|Bacteria,1N9A0@1224|Proteobacteria,1STJ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
HKD3_k127_8767875_0	700598.Niako_6583	1.922e-227	712.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD3_k127_8767875_2	1267211.KI669560_gene707	1.993e-80	270.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1ISKP@117747|Sphingobacteriia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
HKD3_k127_8779774_8	925409.KI911562_gene1988	4.314e-08	55.0	COG3063@1|root,COG3063@2|Bacteria,4PKQM@976|Bacteroidetes,1J0N6@117747|Sphingobacteriia	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HKD3_k127_8779774_2	700598.Niako_4137	2.073e-122	407.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1IQ7X@117747|Sphingobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
HKD3_k127_8779774_4	525244.HMPREF0023_1293	1.939e-66	232.0	COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,1S2UY@1236|Gammaproteobacteria,3NKSF@468|Moraxellaceae	1236|Gammaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD3_k127_8779774_5	925409.KI911562_gene2572	2.482e-51	188.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD3_k127_8779774_1	700598.Niako_0416	2.158e-137	442.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_8779774_0	1267211.KI669560_gene464	3.057e-139	464.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes	976|Bacteroidetes	P	Transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
HKD3_k127_8779774_10	1197906.CAJQ02000027_gene1525	3.302e-06	53.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD3_k127_8779774_3	1121481.AUAS01000003_gene3676	4.877e-106	390.0	COG2831@1|root,COG3227@1|root,COG2831@2|Bacteria,COG3227@2|Bacteria,4PKQC@976|Bacteroidetes,47SGA@768503|Cytophagia	976|Bacteroidetes	E	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M9,Peptidase_M9_N
HKD3_k127_8779774_9	1034807.FBFL15_0799	1.094e-06	63.0	COG1345@1|root,COG1404@1|root,COG3291@1|root,COG3391@1|root,COG4412@1|root,COG4625@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4625@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,He_PIG,fn3
HKD3_k127_8779774_11	983548.Krodi_0329	8.873e-05	57.0	COG1345@1|root,COG1361@1|root,COG3420@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3420@2|Bacteria,4NMB8@976|Bacteroidetes,1IJJU@117743|Flavobacteriia,37EXG@326319|Dokdonia	976|Bacteroidetes	MN	Laminin G domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
HKD3_k127_8779774_6	459349.CLOAM0801	2.44e-35	153.0	COG1404@1|root,COG2133@1|root,COG2356@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG2356@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,CHU_C,FlgD_ig,LTD,Malectin,VCBS,fn3
HKD3_k127_8779774_7	459349.CLOAM0801	1.684e-31	140.0	COG1404@1|root,COG2133@1|root,COG2356@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG2356@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,CHU_C,FlgD_ig,LTD,Malectin,VCBS,fn3
HKD3_k127_8784264_1	1267211.KI669560_gene2394	1.405e-223	701.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1INS9@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
HKD3_k127_8784264_4	1434325.AZQN01000003_gene2488	2.186e-109	370.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,47JVE@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
HKD3_k127_8784264_5	865937.Gilli_1034	4.625e-107	357.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes,1HY7V@117743|Flavobacteriia	976|Bacteroidetes	S	COG3621 Patatin	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
HKD3_k127_8784264_6	1267211.KI669560_gene2395	3.075e-67	239.0	COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,1IS9J@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_8784264_3	700598.Niako_5097	4.007e-136	439.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,1IQR5@117747|Sphingobacteriia	976|Bacteroidetes	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
HKD3_k127_8784264_7	925409.KI911562_gene368	2.127e-62	220.0	COG0122@1|root,COG0122@2|Bacteria,4NMMI@976|Bacteroidetes,1IU7D@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM HhH-GPD superfamily base excision DNA repair protein	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HKD3_k127_8784264_8	925409.KI911562_gene369	2.926e-62	221.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1IRZT@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
HKD3_k127_8784264_10	485918.Cpin_0801	1.356e-38	149.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_8784264_13	1267534.KB906754_gene3266	2.148e-06	60.0	2C8GB@1|root,33F84@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8784264_0	925409.KI911562_gene2192	1.036e-251	782.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1IPSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD3_k127_8784264_11	763034.HMPREF9446_00846	1.244e-15	80.0	COG1669@1|root,COG1669@2|Bacteria,4NV8X@976|Bacteroidetes,2FTGR@200643|Bacteroidia,4ARCQ@815|Bacteroidaceae	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
HKD3_k127_8784264_12	592029.DDD_3044	2.191e-07	57.0	COG2361@1|root,COG2361@2|Bacteria,4NSEC@976|Bacteroidetes,1I441@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
HKD3_k127_8784264_2	1123248.KB893370_gene5006	5.541e-183	581.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
HKD3_k127_8784264_9	1123248.KB893370_gene5005	2.068e-51	188.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1ISX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
HKD3_k127_8784264_14	929713.NIASO_03990	0.0005063	50.0	2DPQE@1|root,332Z6@2|Bacteria,4NXFJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8793807_0	519989.ECTPHS_12697	5.641e-278	863.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1WXVD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
HKD3_k127_8793807_3	1267211.KI669560_gene2761	5.808e-32	130.0	2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,1ITUK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8793807_1	1123248.KB893315_gene3103	1.551e-108	357.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1INS0@117747|Sphingobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
HKD3_k127_8793807_2	700598.Niako_6968	2.49e-63	229.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IT0W@117747|Sphingobacteriia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
HKD3_k127_8809919_1	925409.KI911562_gene508	3.305e-172	544.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1IRA7@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
HKD3_k127_8809919_2	700598.Niako_5742	4.828e-73	256.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HKD3_k127_8809919_0	925409.KI911562_gene379	4.643e-197	630.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1IQCU@117747|Sphingobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD3_k127_8815882_3	1123277.KB893179_gene3096	1.188e-40	154.0	COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,47PSM@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
HKD3_k127_8815882_0	700598.Niako_6863	4.651e-263	818.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1INQA@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HKD3_k127_8815882_1	1185876.BN8_03018	5.104e-59	211.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,47PZ0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_8815882_2	925409.KI911562_gene1174	8.762e-45	167.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD3_k127_8959382_1	485918.Cpin_6500	4.814e-95	318.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1ISWJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
HKD3_k127_8959382_2	925409.KI911562_gene1434	2.425e-50	188.0	COG1587@1|root,COG1587@2|Bacteria,4NNSC@976|Bacteroidetes	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD3_k127_8959382_0	1123248.KB893385_gene4862	2.233e-179	565.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1INQH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
HKD3_k127_8959453_8	700598.Niako_4446	3.273e-86	293.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1IP76@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_8959453_1	700598.Niako_5295	2.86e-222	697.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,1IQ2E@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
HKD3_k127_8959453_4	714943.Mucpa_3658	4.999e-153	490.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1IR2C@117747|Sphingobacteriia	976|Bacteroidetes	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HKD3_k127_8959453_10	925409.KI911562_gene1402	6.526e-62	216.0	COG2731@1|root,COG2731@2|Bacteria,4NQU1@976|Bacteroidetes,1ISSV@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
HKD3_k127_8959453_3	925409.KI911562_gene1403	5.321e-201	633.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1IRCP@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HKD3_k127_8959453_9	1150600.ADIARSV_2121	1.641e-83	284.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,1IRQT@117747|Sphingobacteriia	976|Bacteroidetes	G	Aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
HKD3_k127_8959453_0	760192.Halhy_4403	1.322e-229	724.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,1IP7D@117747|Sphingobacteriia	976|Bacteroidetes	G	major facilitator superfamily	exuT	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
HKD3_k127_8959453_2	925409.KI911562_gene1525	1.088e-213	673.0	COG1232@1|root,COG1232@2|Bacteria,4NJNP@976|Bacteroidetes	976|Bacteroidetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
HKD3_k127_8959453_11	1267211.KI669560_gene1638	2.459e-50	185.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1ISC5@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphoesterase PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_8959453_7	929713.NIASO_03775	2.125e-129	427.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,1IPRI@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Bacterial Fmu (Sun) eukaryotic nucleolar NOL1 Nop2p	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
HKD3_k127_8959453_15	925409.KI911562_gene1580	4.947e-10	70.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	xlyB	-	3.5.1.28	ko:K01447,ko:K01449,ko:K19224	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	CHAP,LysM,YkuD
HKD3_k127_8959453_6	925409.KI911562_gene1581	6.494e-136	439.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1IPT6@117747|Sphingobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HKD3_k127_8959453_5	1123248.KB893323_gene1605	7.423e-142	464.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1IV2A@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HKD3_k127_8959453_12	388413.ALPR1_17383	1.211e-47	178.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47PG1@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K01802,ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HKD3_k127_8959453_14	714943.Mucpa_5102	5.12e-11	65.0	COG0156@1|root,COG0156@2|Bacteria,4NKC1@976|Bacteroidetes,1IS9B@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HKD3_k127_8995909_1	693661.Arcve_1821	5.236e-77	264.0	COG1794@1|root,arCOG02005@2157|Archaea,2XWZW@28890|Euryarchaeota,246CZ@183980|Archaeoglobi	183980|Archaeoglobi	M	aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
HKD3_k127_8995909_3	1239962.C943_01292	3.417e-40	159.0	2E3FB@1|root,32YE4@2|Bacteria,4P77I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8995909_2	1239962.C943_01293	5.147e-56	203.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD3_k127_8995909_0	348824.LPU83_3753	1.089e-79	279.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,4BC1H@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_9013677_0	1107311.Q767_10395	3.196e-153	490.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1HWM0@117743|Flavobacteriia,2NTAJ@237|Flavobacterium	976|Bacteroidetes	J	metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HKD3_k127_9013677_2	472759.Nhal_2106	5.575e-67	236.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria,1WXV0@135613|Chromatiales	135613|Chromatiales	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD3_k127_9013677_4	1237149.C900_02000	5.994e-47	177.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,4NE9M@976|Bacteroidetes,47P55@768503|Cytophagia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
HKD3_k127_9013677_1	760192.Halhy_4201	2.303e-120	396.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD3_k127_9013677_3	1123277.KB893177_gene3494	9.177e-55	201.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47MTX@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_9013677_5	926549.KI421517_gene2435	4.856e-36	144.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47JDV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD3_k127_9018210_2	1123248.KB893340_gene2667	9.381e-151	486.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_9018210_3	700598.Niako_2564	2.83e-115	384.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,1ISMP@117747|Sphingobacteriia	976|Bacteroidetes	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD3_k127_9018210_1	1267211.KI669560_gene1665	2.604e-207	648.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
HKD3_k127_9018210_0	1538644.KO02_23015	2.687e-209	662.0	COG4935@1|root,COG4935@2|Bacteria,4NGW4@976|Bacteroidetes,1J10S@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
HKD3_k127_9058686_2	468059.AUHA01000002_gene114	4.331e-14	72.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1IPV7@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_9058686_1	1122605.KB893627_gene2991	1.915e-100	333.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,1IQJP@117747|Sphingobacteriia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
HKD3_k127_9058686_0	925409.KI911562_gene2010	3.271e-127	425.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1IP87@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD3_k127_9123417_2	929713.NIASO_09225	3.614e-95	319.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1IPGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
HKD3_k127_9123417_3	1121896.JMLU01000024_gene2532	9.672e-92	307.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1HYYD@117743|Flavobacteriia,2NU88@237|Flavobacterium	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
HKD3_k127_9123417_0	1121889.AUDM01000004_gene2634	2.122e-180	572.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia,2NTN7@237|Flavobacterium	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
HKD3_k127_9123417_1	1267211.KI669560_gene1635	3.157e-119	393.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD3_k127_9123417_4	1107311.Q767_05715	4.63e-63	217.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,2NSJJ@237|Flavobacterium	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD3_k127_9131218_2	1279009.ADICEAN_02033	1.1e-27	115.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,47PTG@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
HKD3_k127_9131218_0	485918.Cpin_2750	0.0	1499.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IRKC@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD3_k127_9131218_1	555779.Dthio_PD3181	6.712e-46	177.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9137846_3	700598.Niako_7323	5.263e-105	347.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD3_k127_9137846_2	1123248.KB893329_gene4488	1.378e-157	507.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD3_k127_9137846_1	1267211.KI669560_gene1188	1.177e-199	630.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD3_k127_9137846_0	1123248.KB893329_gene4486	1.695e-203	640.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HKD3_k127_9137846_4	929713.NIASO_19570	2.802e-64	223.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_9189441_5	925409.KI911562_gene889	3.177e-51	183.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes	976|Bacteroidetes	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_9189441_3	925409.KI911562_gene617	1.281e-117	386.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1IQ5S@117747|Sphingobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
HKD3_k127_9189441_2	925409.KI911562_gene616	6.063e-148	474.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1IVKB@117747|Sphingobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
HKD3_k127_9189441_4	90814.KL370891_gene30	3.376e-68	238.0	COG0406@1|root,COG0406@2|Bacteria,1N8GN@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
HKD3_k127_9189441_1	925409.KI911562_gene612	4.536e-229	718.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_9189441_0	1123248.KB893319_gene4058	0.0	1154.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD3_k127_9189441_6	1279009.ADICEAN_02061	9.51e-12	68.0	COG1929@1|root,COG1929@2|Bacteria,4NFK8@976|Bacteroidetes,47MW7@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
HKD3_k127_9192974_11	1121930.AQXG01000011_gene1757	2.165e-34	137.0	COG3324@1|root,COG3324@2|Bacteria,4NTUQ@976|Bacteroidetes,1IZ1H@117747|Sphingobacteriia	976|Bacteroidetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_9192974_7	1123248.KB893331_gene3801	7.354e-119	408.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1IPZ1@117747|Sphingobacteriia	976|Bacteroidetes	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
HKD3_k127_9192974_6	1123248.KB893331_gene3802	5.682e-128	425.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1IXCQ@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
HKD3_k127_9192974_9	1123277.KB893172_gene670	2.529e-45	170.0	COG0664@1|root,COG0664@2|Bacteria,4NSMK@976|Bacteroidetes,47PC0@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_9192974_13	1123248.KB893345_gene38	1.835e-23	115.0	2DTG8@1|root,33K7P@2|Bacteria,4NYYK@976|Bacteroidetes,1IUD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9192974_14	504472.Slin_2034	8.095e-06	54.0	2F9IQ@1|root,341V2@2|Bacteria,4P51Q@976|Bacteroidetes,47VFR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9192974_3	1123278.KB893544_gene4837	9.896e-156	504.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD3_k127_9192974_0	1123248.KB893348_gene334	1.557e-195	619.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_9192974_1	1237149.C900_04940	1.223e-186	606.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_9192974_5	1267211.KI669560_gene693	4.343e-136	443.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,1INUS@117747|Sphingobacteriia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HKD3_k127_9192974_4	172088.AUGA01000016_gene2484	3.596e-146	491.0	COG1409@1|root,COG1409@2|Bacteria,1RHP4@1224|Proteobacteria,2U9B6@28211|Alphaproteobacteria,3K0V6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD3_k127_9192974_10	700598.Niako_6432	1.096e-35	137.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1ITUM@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
HKD3_k127_9192974_12	700598.Niako_6433	2.401e-32	131.0	2DRKN@1|root,33C6H@2|Bacteria,4NZAT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9192974_2	700598.Niako_6434	1.073e-172	558.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
HKD3_k127_9192974_8	700598.Niako_5667	2.879e-107	359.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_9207725_1	1094466.KQS_08100	2.355e-74	255.0	28KYY@1|root,2ZAEA@2|Bacteria,4NQHX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9207725_0	925409.KI911562_gene1693	1.682e-121	397.0	COG2253@1|root,COG2253@2|Bacteria,4NGNE@976|Bacteroidetes,1IY7J@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
HKD3_k127_9207725_2	1121859.KB890739_gene2374	6.803e-70	241.0	COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,47KSF@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
HKD3_k127_9223321_4	313596.RB2501_05420	2.157e-144	470.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HKD3_k127_9223321_15	1122605.KB893643_gene734	7.842e-09	63.0	COG1917@1|root,COG1917@2|Bacteria,4NR0K@976|Bacteroidetes,1IT3Z@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD3_k127_9223321_10	1267211.KI669560_gene394	6.387e-88	297.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1IR8K@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HKD3_k127_9223321_14	1123073.KB899241_gene2400	1.914e-19	89.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9223321_12	925409.KI911562_gene409	2.54e-75	263.0	COG2017@1|root,COG2017@2|Bacteria,4NKUK@976|Bacteroidetes,1IYMB@117747|Sphingobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HKD3_k127_9223321_5	1123248.KB893321_gene471	2.33e-141	458.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD3_k127_9223321_9	1267211.KI669560_gene854	3.854e-95	325.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD3_k127_9223321_3	700598.Niako_6850	4.301e-146	488.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1J0U3@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
HKD3_k127_9223321_13	700598.Niako_6851	2.072e-39	160.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,1IUMD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
HKD3_k127_9223321_6	700598.Niako_6852	9.27e-128	413.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1IPP4@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD3_k127_9223321_1	1123248.KB893359_gene2113	1.126e-238	757.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HKD3_k127_9223321_2	1123248.KB893359_gene2112	2.056e-219	687.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1IP8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD3_k127_9223321_11	700598.Niako_6855	7.264e-87	293.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1ISRG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9223321_7	700598.Niako_6856	5.53e-125	417.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
HKD3_k127_9223321_8	700598.Niako_6857	7.976e-97	328.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1IQ08@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility associated	gldN	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9223321_0	700598.Niako_6858	6.92e-268	836.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1IPMR@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD3_k127_9229541_8	485918.Cpin_7005	1.507e-56	211.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1INVB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Aminoglycoside phosphotransferase	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
HKD3_k127_9229541_1	509635.N824_23255	1.589e-221	694.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1IPU8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD3_k127_9229541_4	700598.Niako_6054	1.937e-124	409.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1IPSX@117747|Sphingobacteriia	976|Bacteroidetes	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
HKD3_k127_9229541_3	929713.NIASO_15950	9.287e-198	627.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1IQIK@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD3_k127_9229541_9	700598.Niako_6237	2.106e-43	166.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,1IUI6@117747|Sphingobacteriia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9229541_7	1123248.KB893331_gene3807	5.369e-59	215.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,1IT01@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD3_k127_9229541_11	700598.Niako_5595	1.332e-20	94.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1ITBU@117747|Sphingobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HKD3_k127_9229541_0	925409.KI911562_gene1181	0.0	1055.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HKD3_k127_9229541_2	925409.KI911562_gene1180	1.019e-215	681.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD3_k127_9229541_6	700598.Niako_5589	2.356e-62	223.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1INQF@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HKD3_k127_9229541_5	1122605.KB893637_gene3068	9.432e-104	344.0	COG0861@1|root,COG0861@2|Bacteria,4NH6F@976|Bacteroidetes,1J0BP@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
HKD3_k127_9229541_10	700598.Niako_5587	1.942e-29	119.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD3_k127_9363698_4	468059.AUHA01000003_gene1685	4.275e-66	229.0	COG2271@1|root,COG2271@2|Bacteria,4NG3R@976|Bacteroidetes,1IW8Q@117747|Sphingobacteriia	976|Bacteroidetes	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
HKD3_k127_9363698_5	1089547.KB913013_gene2326	3.002e-57	211.0	COG2320@1|root,COG2320@2|Bacteria,4NNC5@976|Bacteroidetes,47S6Y@768503|Cytophagia	976|Bacteroidetes	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
HKD3_k127_9363698_9	324925.Ppha_1113	4.597e-24	105.0	2ESXY@1|root,33KG8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9363698_7	468059.AUHA01000003_gene1789	1.663e-53	196.0	2EIQA@1|root,33CFR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9363698_1	929562.Emtol_2237	2.47e-149	476.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,47M8V@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD3_k127_9363698_0	1267211.KI669560_gene2157	0.0	1229.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1IQZ2@117747|Sphingobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
HKD3_k127_9363698_3	700598.Niako_7343	2.133e-113	373.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1INST@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
HKD3_k127_9363698_10	926551.KB900737_gene438	6.384e-24	109.0	2E858@1|root,332IT@2|Bacteria,4NVGV@976|Bacteroidetes,1I56Y@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9363698_6	153721.MYP_165	4.366e-54	197.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,47P7G@768503|Cytophagia	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9363698_8	929556.Solca_0502	6.98e-35	136.0	COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,1IT7Z@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
HKD3_k127_9363698_2	468059.AUHA01000005_gene2428	1.229e-144	470.0	2CA5R@1|root,2Z81H@2|Bacteria,4NGSF@976|Bacteroidetes,1IV7P@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
HKD3_k127_9383127_0	1123234.AUKI01000016_gene3086	0.0	1158.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,1I0UR@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate formate lyase-like	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HKD3_k127_9383127_3	1123234.AUKI01000016_gene3087	3.437e-110	361.0	COG1180@1|root,COG1180@2|Bacteria,4NHMK@976|Bacteroidetes,1HXTA@117743|Flavobacteriia	976|Bacteroidetes	O	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HKD3_k127_9383127_10	700598.Niako_2159	3.145e-30	121.0	COG4281@1|root,COG4281@2|Bacteria,4NVK0@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-coA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ACBP
HKD3_k127_9383127_1	1239962.C943_03737	2.085e-230	727.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD3_k127_9383127_5	1034807.FBFL15_1759	4.039e-71	250.0	COG2304@1|root,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,1HZ8Q@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD3_k127_9383127_8	1121930.AQXG01000001_gene1295	1.511e-40	161.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2
HKD3_k127_9383127_11	1219084.AP014508_gene1924	5.009e-12	79.0	COG2273@1|root,COG2273@2|Bacteria,2GDVB@200918|Thermotogae	200918|Thermotogae	G	PFAM glycoside hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_16
HKD3_k127_9383127_6	1121889.AUDM01000007_gene953	5.292e-61	236.0	2DFI1@1|root,2ZRXN@2|Bacteria,4PPKY@976|Bacteroidetes,1IKQI@117743|Flavobacteriia,2NVZ1@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9383127_9	1279009.ADICEAN_02097	1.876e-40	172.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9383127_2	1341181.FLJC2902T_31020	7.149e-111	369.0	arCOG10456@1|root,2ZA6T@2|Bacteria,4NGZ2@976|Bacteroidetes,1HXIA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9383127_4	700598.Niako_2054	6.191e-98	325.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HKD3_k127_9383127_7	1121904.ARBP01000001_gene5413	1.258e-58	210.0	COG1943@1|root,COG1943@2|Bacteria,4P2UQ@976|Bacteroidetes,47UPN@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD3_k127_9446659_5	700598.Niako_6461	2.011e-77	262.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9446659_11	1123248.KB893322_gene686	2.506e-08	61.0	2E5JG@1|root,330AS@2|Bacteria,4NWYV@976|Bacteroidetes,1ITWB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9446659_10	404380.Gbem_3356	8.313e-16	79.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,42WU5@68525|delta/epsilon subdivisions,2WRRS@28221|Deltaproteobacteria,43SRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
HKD3_k127_9446659_0	1267211.KI669560_gene730	1.927e-189	601.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,1IRA1@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD3_k127_9446659_7	1121859.KB890757_gene1570	2.513e-53	194.0	2CB46@1|root,31GHU@2|Bacteria,4P0TC@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
HKD3_k127_9446659_4	929556.Solca_2194	1.457e-99	344.0	COG4942@1|root,COG4942@2|Bacteria,4P0BC@976|Bacteroidetes,1IXE6@117747|Sphingobacteriia	976|Bacteroidetes	D	Protein of unknown function (DUF3375)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
HKD3_k127_9446659_1	1267211.KI669560_gene2853	1.761e-182	577.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD3_k127_9446659_8	1123248.KB893348_gene308	2.125e-27	115.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1ITVQ@117747|Sphingobacteriia	976|Bacteroidetes	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
HKD3_k127_9446659_3	1122176.KB903536_gene1761	1.257e-100	346.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9446659_6	761193.Runsl_1556	5.938e-69	249.0	COG0349@1|root,COG0349@2|Bacteria,4NP62@976|Bacteroidetes,47QTK@768503|Cytophagia	976|Bacteroidetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
HKD3_k127_9446659_2	1267211.KI669560_gene731	1.054e-121	399.0	COG1647@1|root,COG1647@2|Bacteria,4NHPY@976|Bacteroidetes,1IQS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,BAAT_C,Hydrolase_4
HKD3_k127_9446659_9	929562.Emtol_1394	3.46e-25	110.0	COG1943@1|root,COG1943@2|Bacteria,4NQR4@976|Bacteroidetes,47QSX@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD3_k127_9516942_0	925409.KI911562_gene2955	6.737e-145	463.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1IQ2W@117747|Sphingobacteriia	976|Bacteroidetes	M	2-dehydro-3-deoxyphosphooctonate aldolase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
HKD3_k127_9516942_1	909613.UO65_5584	4.452e-51	201.0	COG2374@1|root,COG4625@1|root,COG4733@1|root,COG5492@1|root,COG2374@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,2I2E0@201174|Actinobacteria	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
HKD3_k127_9516942_3	700598.Niako_2539	1.219e-11	78.0	COG1361@1|root,COG1404@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1IW54@117747|Sphingobacteriia	976|Bacteroidetes	O	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
HKD3_k127_9516942_2	700598.Niako_4482	9.721e-26	108.0	COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,1IUHT@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
HKD3_k127_9516942_4	866536.Belba_2406	1.9e-10	62.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HKD3_k127_9520759_2	643867.Ftrac_1239	0.0001969	49.0	COG2911@1|root,COG4932@1|root,COG5644@1|root,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
HKD3_k127_9520759_0	700598.Niako_5754	1.465e-146	478.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IR4K@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
HKD3_k127_9520759_1	700598.Niako_5755	1.259e-141	460.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1IQCH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD3_k127_9637453_0	929556.Solca_2958	6.625e-186	593.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQPI@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
HKD3_k127_9637453_1	1123248.KB893323_gene1602	3.016e-28	118.0	COG1266@1|root,COG1266@2|Bacteria,4NHRW@976|Bacteroidetes,1IYXV@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_971205_3	1537917.JU82_10375	3.317e-97	325.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,43DST@68525|delta/epsilon subdivisions,2YNGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase-4, component G	-	-	-	ko:K14090	-	-	-	-	ko00000	-	-	-	Complex1_49kDa,NiFeSe_Hases
HKD3_k127_971205_8	709032.Sulku_2060	1.608e-24	107.0	COG0852@1|root,COG0852@2|Bacteria,1Q346@1224|Proteobacteria,42WRC@68525|delta/epsilon subdivisions,2YQIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa
HKD3_k127_971205_5	868864.Dester_0742	4.856e-74	252.0	COG3260@1|root,COG3260@2|Bacteria,2G48H@200783|Aquificae	200783|Aquificae	C	PFAM NADH ubiquinone oxidoreductase, 20	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
HKD3_k127_971205_4	648996.Theam_0481	6.581e-85	296.0	COG0650@1|root,COG0650@2|Bacteria,2G4FQ@200783|Aquificae	200783|Aquificae	C	respiratory-chain NADH dehydrogenase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
HKD3_k127_971205_2	868864.Dester_0744	3.221e-112	385.0	COG1009@1|root,COG1009@2|Bacteria,2G4R9@200783|Aquificae	200783|Aquificae	C	PFAM NADH Ubiquinone plastoquinone	-	-	-	ko:K14086	-	-	-	-	ko00000	-	-	-	Proton_antipo_M,Proton_antipo_N
HKD3_k127_971205_9	931627.MycrhDRAFT_5197	4.644e-20	96.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_971205_0	697282.Mettu_1511	6.376e-179	574.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,1XDSA@135618|Methylococcales	135618|Methylococcales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
HKD3_k127_971205_7	350058.Mvan_4114	6.174e-55	209.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria,233M7@1762|Mycobacteriaceae	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
HKD3_k127_971205_6	381666.PHG089	3.303e-57	216.0	COG3383@1|root,COG3383@2|Bacteria,1MXTC@1224|Proteobacteria,2WGYK@28216|Betaproteobacteria,1KIJI@119060|Burkholderiaceae	28216|Betaproteobacteria	F	4Fe-4S single cluster domain	hoxU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18006	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
HKD3_k127_971205_1	381666.PHG088	9.932e-137	449.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,1K4IR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hoxF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
HKD3_k127_9872_1	925409.KI911562_gene2257	8.909e-266	852.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1IPPH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
HKD3_k127_9872_3	1123248.KB893316_gene4577	8.633e-106	363.0	COG1629@1|root,COG4771@2|Bacteria,4PKB3@976|Bacteroidetes,1IPFQ@117747|Sphingobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
HKD3_k127_9872_9	1123248.KB893316_gene4578	1.075e-06	57.0	2ET5Y@1|root,33KQ0@2|Bacteria,4NZGA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9872_2	925409.KI911562_gene2065	4.464e-121	396.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HKD3_k127_9872_7	1122605.KB893625_gene2075	5.867e-27	110.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1IU0H@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HKD3_k127_9872_4	700598.Niako_4343	1.975e-78	268.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1ISWG@117747|Sphingobacteriia	976|Bacteroidetes	S	acr, cog1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
HKD3_k127_9872_5	1123248.KB893359_gene2093	2.032e-42	162.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD3_k127_9872_6	1237149.C900_02076	1.67e-30	128.0	COG1416@1|root,COG1416@2|Bacteria,4NQQE@976|Bacteroidetes,47YKC@768503|Cytophagia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
HKD3_k127_9872_8	1121288.AULL01000013_gene1662	2.021e-12	73.0	2EAT9@1|root,334V5@2|Bacteria,4NUP8@976|Bacteroidetes,1I6RQ@117743|Flavobacteriia,3ZT0R@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9872_0	1267211.KI669560_gene1016	0.0	1427.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
## 2966 queries scanned
## Total time (seconds): 98.00709104537964
## Rate: 30.26 q/s