## Sat Nov 16 12:21:52 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin9/HKD_3_bin.6.fa -m mmseqs --itype genome -o HKD_3_bin.6 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HKD_3_bin.6 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD3_k127_108070_3	574375.BAGA_03600	1.237e-117	380.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
HKD3_k127_108070_4	1347369.CCAD010000057_gene4125	4.533e-90	298.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,1ZD01@1386|Bacillus	91061|Bacilli	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HKD3_k127_108070_1	315749.Bcer98_3125	0.0	1039.0	COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
HKD3_k127_108070_0	1169144.KB910936_gene1246	0.0	1041.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD3_k127_108070_6	574375.BAGA_03625	1.939e-35	137.0	2DPWE@1|root,333P0@2|Bacteria,1VIIN@1239|Firmicutes,4HNK2@91061|Bacilli,1ZQN6@1386|Bacillus	91061|Bacilli	G	Post-transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Post_transc_reg
HKD3_k127_108070_2	315749.Bcer98_3129	9.7e-222	698.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_108070_5	1169144.KB910936_gene1242	4.682e-83	280.0	COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,4HHEY@91061|Bacilli,1ZDIR@1386|Bacillus	91061|Bacilli	S	membrane	yrbG	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD3_k127_109199_2	574376.BAMA_17655	7.973e-08	53.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HKAA@91061|Bacilli,1ZQWN@1386|Bacillus	91061|Bacilli	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HKD3_k127_109199_0	1396.DJ87_3452	6.244e-224	697.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZCBT@1386|Bacillus	91061|Bacilli	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22640	PALP
HKD3_k127_109199_1	315730.BcerKBAB4_1150	2.74e-100	333.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,1ZC5U@1386|Bacillus	91061|Bacilli	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HKD3_k127_11624_9	1169144.KB910940_gene2565	2.109e-77	263.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus	91061|Bacilli	V	ABC transporter	ygaD	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
HKD3_k127_11624_6	315749.Bcer98_0449	3.284e-96	316.0	COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,1ZB2J@1386|Bacillus	91061|Bacilli	J	Belongs to the UPF0374 family	ygaC	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
HKD3_k127_11624_15	1169144.KB910940_gene2562	2.803e-12	71.0	2DS2F@1|root,33E7P@2|Bacteria,1VKTG@1239|Firmicutes,4HSKF@91061|Bacilli	91061|Bacilli	S	Small acid-soluble spore	-	-	-	ko:K06422	-	-	-	-	ko00000	-	-	-	SASP_gamma
HKD3_k127_11624_10	574375.BAGA_20275	2.868e-34	132.0	2BX0I@1|root,335P2@2|Bacteria,1VGI6@1239|Firmicutes,4HM29@91061|Bacilli,1ZR86@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_11624_1	315730.BcerKBAB4_0439	3.457e-172	546.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus	91061|Bacilli	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
HKD3_k127_11624_3	315749.Bcer98_0442	1.774e-155	501.0	COG1988@1|root,COG1988@2|Bacteria,1TQFC@1239|Firmicutes,4H9PU@91061|Bacilli,1ZBEI@1386|Bacillus	91061|Bacilli	S	membrane-bound metal-dependent	yfhP	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD3_k127_11624_12	574376.BAMA_23610	1.604e-33	131.0	2CEK7@1|root,330II@2|Bacteria,1VFTN@1239|Firmicutes,4HNJY@91061|Bacilli,1ZI0N@1386|Bacillus	91061|Bacilli	S	WVELL protein	yfhJ	-	-	-	-	-	-	-	-	-	-	-	WVELL
HKD3_k127_11624_11	574376.BAMA_23595	6.372e-34	134.0	2C8IW@1|root,32PGC@2|Bacteria,1VADG@1239|Firmicutes,4HNM3@91061|Bacilli,1ZH1I@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1811)	yfhH	-	-	-	-	-	-	-	-	-	-	-	DUF1811
HKD3_k127_11624_8	574376.BAMA_23590	4.008e-88	299.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,1ZC8N@1386|Bacillus	91061|Bacilli	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HKD3_k127_11624_4	1405.DJ92_3090	5.765e-116	380.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus	91061|Bacilli	S	nucleoside-diphosphate sugar epimerase	yfhF	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
HKD3_k127_11624_0	1405.DJ92_3089	1.639e-184	583.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,4H9VP@91061|Bacilli,1ZBB1@1386|Bacillus	91061|Bacilli	Q	COG1228 Imidazolonepropionase and related amidohydrolases	hutI	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD3_k127_11624_7	574376.BAMA_23575	1.882e-88	296.0	COG1670@1|root,COG1670@2|Bacteria,1V0BB@1239|Firmicutes,4HAK2@91061|Bacilli,1ZDJN@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_11624_2	574375.BAGA_20215	3.901e-166	529.0	COG0707@1|root,COG0707@2|Bacteria,1TR07@1239|Firmicutes,4HBKJ@91061|Bacilli,1ZQUQ@1386|Bacillus	91061|Bacilli	M	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)	ugtP	GO:0003674,GO:0003824,GO:0008194,GO:0016740,GO:0016757,GO:0016758,GO:0035251,GO:0046527,GO:0047228	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD3_k127_11624_5	649639.Bcell_0772	2.878e-104	343.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli,1ZE84@1386|Bacillus	91061|Bacilli	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HKD3_k127_1250617_1	1347369.CCAD010000049_gene411	4.331e-77	262.0	COG4347@1|root,COG4347@2|Bacteria,1V1NI@1239|Firmicutes,4HFTW@91061|Bacilli,1ZFJF@1386|Bacillus	91061|Bacilli	S	membrane	ypjA	-	-	-	-	-	-	-	-	-	-	-	DUF1405
HKD3_k127_1250617_2	1169144.KB910925_gene155	2.11e-65	233.0	28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus	91061|Bacilli	S	sporulation protein	ypjB	-	-	-	-	-	-	-	-	-	-	-	Spore_YpjB
HKD3_k127_1250617_0	1169144.KB910925_gene154	6.89e-107	350.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,1ZD1M@1386|Bacillus	91061|Bacilli	S	Zn-dependent protease	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HKD3_k127_1257479_0	1051501.AYTL01000028_gene1684	3.588e-145	464.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,1ZCEN@1386|Bacillus	91061|Bacilli	O	COG1331 Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
HKD3_k127_1257479_1	1444310.JANV01000142_gene3761	1.016e-58	207.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,1ZGQ9@1386|Bacillus	91061|Bacilli	I	Acyl-CoA hydrolase	ykhA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_1262586_3	545693.BMQ_2708	3.293e-26	107.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus	91061|Bacilli	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD3_k127_1262586_1	935837.JAEK01000012_gene336	3.844e-68	237.0	COG4126@1|root,COG4126@2|Bacteria,1VA6Q@1239|Firmicutes,4ISRI@91061|Bacilli,1ZS65@1386|Bacillus	91061|Bacilli	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1262586_2	1408424.JHYI01000011_gene1370	9.357e-67	233.0	COG5582@1|root,COG5582@2|Bacteria,1VY3M@1239|Firmicutes,4HWZE@91061|Bacilli,1ZH37@1386|Bacillus	91061|Bacilli	S	UPF0302 domain	-	-	-	-	-	-	-	-	-	-	-	-	IDEAL,UPF0302
HKD3_k127_1262586_0	1243664.CAVL020000005_gene350	8.265e-116	375.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZC6E@1386|Bacillus	91061|Bacilli	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_1283475_0	1117379.BABA_18117	0.0	1284.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus	91061|Bacilli	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD3_k127_1283475_1	1117379.BABA_18097	2.36e-28	115.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,1ZBIC@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD3_k127_128527_3	1405.DJ92_1850	3.982e-141	452.0	2C5HJ@1|root,2Z812@2|Bacteria,1TQQ6@1239|Firmicutes,4HA3F@91061|Bacilli,1ZCGB@1386|Bacillus	91061|Bacilli	S	Tetraprenyl-beta-curcumene synthase	ytpB	-	4.2.3.130	ko:K16188	-	-	R10009	RC02994	ko00000,ko01000	-	-	-	DUF2600
HKD3_k127_128527_4	574376.BAMA_05545	1.91e-83	281.0	COG0275@1|root,COG0275@2|Bacteria,1UHPG@1239|Firmicutes,4IS5B@91061|Bacilli,1ZFKV@1386|Bacillus	91061|Bacilli	M	Putative rRNA methylase	ytqB	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
HKD3_k127_128527_1	1169144.KB910930_gene1645	4.078e-186	586.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli,1ZBM1@1386|Bacillus	91061|Bacilli	S	Fe-S oxidoreductase	ytqA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
HKD3_k127_128527_5	1169144.KB910930_gene1646	1.689e-20	93.0	29JW2@1|root,306TD@2|Bacteria,1U0BH@1239|Firmicutes,4I9NA@91061|Bacilli,1ZISQ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2524)	ytzC	-	-	-	-	-	-	-	-	-	-	-	DUF2524
HKD3_k127_128527_2	574375.BAGA_25700	8.611e-162	518.0	COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,1ZBPE@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	yttB	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_128527_0	1382358.JHVN01000012_gene2068	0.0	1458.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,21V55@150247|Anoxybacillus	91061|Bacilli	J	Leucyl-tRNA synthetase, Domain 2	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HKD3_k127_128527_7	574376.BAMA_05415	2.641e-06	51.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZH5X@1386|Bacillus	91061|Bacilli	P	Sulfurtransferase	ytwF	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_1300787_5	574375.BAGA_12100	1.159e-45	168.0	COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,1ZI79@1386|Bacillus	91061|Bacilli	S	Membrane	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
HKD3_k127_1300787_1	1169144.KB910948_gene3625	1.281e-174	550.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,1ZD05@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HKD3_k127_1300787_3	1169144.KB910948_gene3624	1.512e-145	464.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,1ZAR8@1386|Bacillus	91061|Bacilli	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HKD3_k127_1300787_4	265729.GS18_0213500	1.399e-92	307.0	COG0110@1|root,COG0110@2|Bacteria,1V1SM@1239|Firmicutes,4HFTP@91061|Bacilli,1ZBJ5@1386|Bacillus	91061|Bacilli	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	yvoF	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
HKD3_k127_1300787_0	1169144.KB910948_gene3621	6.243e-199	631.0	COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yvcD	-	-	-	-	-	-	-	-	-	-	-	HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8
HKD3_k127_1300787_2	315749.Bcer98_3701	2.661e-157	497.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_1317656_4	1403313.AXBR01000023_gene2578	9.992e-73	246.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus	91061|Bacilli	G	phosphotransferase system	scrA	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HKD3_k127_1317656_1	665952.HMPREF1015_02912	1.589e-140	453.0	COG1609@1|root,COG1609@2|Bacteria,1TSIJ@1239|Firmicutes,4HC90@91061|Bacilli,1ZD1Z@1386|Bacillus	91061|Bacilli	K	helix_turn _helix lactose operon repressor	scrR	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4
HKD3_k127_1317656_0	574375.BAGA_15500	3.588e-292	915.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus	91061|Bacilli	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
HKD3_k127_1317656_3	935837.JAEK01000006_gene4285	8.463e-98	330.0	COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,1ZAW6@1386|Bacillus	91061|Bacilli	T	Belongs to the peptidase S16 family	-	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
HKD3_k127_1317656_5	562743.JH976435_gene3320	1.983e-65	230.0	COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli	91061|Bacilli	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
HKD3_k127_1317656_2	1196322.A370_01358	5.426e-121	395.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia,36FD0@31979|Clostridiaceae	186801|Clostridia	L	hmm pf00665	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
HKD3_k127_1321066_5	574376.BAMA_06005	6.442e-79	264.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,1ZAPW@1386|Bacillus	91061|Bacilli	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_1321066_10	315749.Bcer98_1660	2.327e-36	143.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,1ZJSR@1386|Bacillus	91061|Bacilli	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD3_k127_1321066_8	1169144.KB910934_gene4309	9.5e-45	168.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,4HM61@91061|Bacilli,1ZQ4A@1386|Bacillus	91061|Bacilli	S	DUF218 domain	sanA	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD3_k127_1321066_9	1382306.JNIM01000001_gene2106	7.16e-38	162.0	COG1401@1|root,COG1401@2|Bacteria,2G8DS@200795|Chloroflexi	200795|Chloroflexi	L	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
HKD3_k127_1321066_2	1169144.KB910934_gene4303	1.816e-191	616.0	2C3CH@1|root,32RC1@2|Bacteria,1V9I0@1239|Firmicutes,4HIFF@91061|Bacilli,1ZCQ1@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1321066_7	1396.DJ87_2538	3.523e-67	234.0	29RIV@1|root,30CMX@2|Bacteria,1UA47@1239|Firmicutes,4IKDY@91061|Bacilli,1ZGNR@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1321066_11	1169144.KB910934_gene4300	6.241e-25	112.0	COG0789@1|root,COG0789@2|Bacteria,1VH5D@1239|Firmicutes,4HQ0J@91061|Bacilli,1ZG6F@1386|Bacillus	91061|Bacilli	K	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure	racA	-	-	ko:K11686	-	-	-	-	ko00000,ko03036	-	-	-	MerR_1
HKD3_k127_1321066_3	574376.BAMA_06150	9.74e-157	503.0	COG4191@1|root,COG4191@2|Bacteria,1TRYP@1239|Firmicutes,4HE85@91061|Bacilli,1ZBXM@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisK_N
HKD3_k127_1321066_4	1169144.KB910934_gene4295	2.216e-84	286.0	COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HGZF@91061|Bacilli,1ZGVY@1386|Bacillus	91061|Bacilli	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD3_k127_1321066_0	1273538.G159_07280	5.26e-249	780.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,26DUW@186818|Planococcaceae	91061|Bacilli	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	iYO844.BSU14520	Adenine_deam_C,Amidohydro_1
HKD3_k127_1321066_6	1121091.AUMP01000041_gene4248	5.51e-69	242.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HKD3_k127_1321066_13	66692.ABC2422	6.814e-10	60.0	2DRND@1|root,33CCV@2|Bacteria,1VNPA@1239|Firmicutes,4HR66@91061|Bacilli,1ZJXX@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (Tiny_TM_bacill)	-	-	-	-	-	-	-	-	-	-	-	-	Tiny_TM_bacill
HKD3_k127_1321066_1	1234664.AMRO01000076_gene2449	6.34e-224	699.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,4HB7F@91061|Bacilli,1WE1I@129337|Geobacillus	91061|Bacilli	S	FAD-dependent	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
HKD3_k127_1333006_3	1178537.BA1_10841	3.85e-36	138.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	ssuB	GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0022857,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098656	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	iYO844.BSU08830	ABC_tran
HKD3_k127_1333006_1	1121091.AUMP01000033_gene1592	1.017e-134	437.0	COG0715@1|root,COG0715@2|Bacteria,1TP8M@1239|Firmicutes,4HCBE@91061|Bacilli	91061|Bacilli	P	NMT1-like family	ssuA	-	-	ko:K15553	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	NMT1
HKD3_k127_1333006_2	545693.BMQ_4715	7.652e-112	368.0	COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HDR7@91061|Bacilli,1ZQFI@1386|Bacillus	91061|Bacilli	P	ABC transporter (permease)	ssuC	-	-	ko:K15554	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	BPD_transp_1
HKD3_k127_1333006_0	1121091.AUMP01000033_gene1595	4.658e-185	584.0	COG2141@1|root,COG2141@2|Bacteria,1TW8W@1239|Firmicutes,4HB95@91061|Bacilli	91061|Bacilli	C	Catalyzes the desulfonation of aliphatic sulfonates	ssuD	-	1.14.14.28,1.14.14.5	ko:K04091,ko:K20938	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HKD3_k127_1340852_6	265729.GS18_0220845	5.509e-23	100.0	COG3339@1|root,COG3339@2|Bacteria,1VB9N@1239|Firmicutes,4HM3U@91061|Bacilli,1ZFMI@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HKD3_k127_1340852_5	1178537.BA1_12274	2.076e-40	154.0	COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,4HYD5@91061|Bacilli,1ZD03@1386|Bacillus	91061|Bacilli	K	transcriptional	yfiV	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
HKD3_k127_1340852_1	1051501.AYTL01000029_gene1573	5.135e-201	638.0	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	yfiU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_1340852_2	198094.BA_5461	2.103e-161	514.0	COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus	91061|Bacilli	C	COG1294 Cytochrome bd-type quinol oxidase, subunit 2	ythB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
HKD3_k127_1340852_0	574375.BAGA_12395	1.496e-214	673.0	COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus	91061|Bacilli	C	oxidase, subunit	ythA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
HKD3_k127_1340852_7	1169144.KB910979_gene1561	4.25e-17	83.0	29TJI@1|root,30ESV@2|Bacteria,1UCXD@1239|Firmicutes,4IPDC@91061|Bacilli,1ZPRF@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1340852_3	1396.DJ87_3991	2.128e-118	392.0	COG1835@1|root,COG1835@2|Bacteria,1V7GP@1239|Firmicutes,4HJ4R@91061|Bacilli	91061|Bacilli	I	transferase activity, transferring acyl groups other than amino-acyl groups	yiaH	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD3_k127_1340852_4	1169144.KB910975_gene2388	4.331e-82	280.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli,1ZGQP@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	nodB3	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_137811_4	1340434.AXVA01000013_gene266	1.644e-150	487.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus	91061|Bacilli	Q	Naringenin-chalcone synthase	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
HKD3_k127_137811_5	315749.Bcer98_1304	2.814e-111	372.0	COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus	91061|Bacilli	P	Protein of unknown function (DUF418)	yrkO	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD3_k127_137811_2	1396.DJ87_5396	1.003e-214	673.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,1ZAUK@1386|Bacillus	91061|Bacilli	F	xanthine	pbuX	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823	-	ko:K16169	-	-	-	-	ko00000,ko02000	2.A.40.3.1	-	-	Xan_ur_permease
HKD3_k127_137811_6	1169144.KB910925_gene118	3.003e-84	284.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,1ZFTS@1386|Bacillus	91061|Bacilli	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	iYO844.BSU22070	Pribosyltran
HKD3_k127_137811_1	315730.BcerKBAB4_1487	1.756e-237	745.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,4HAPE@91061|Bacilli,1ZB3X@1386|Bacillus	91061|Bacilli	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	ypwA	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
HKD3_k127_137811_0	574376.BAMA_14285	1.824e-316	979.0	COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus	91061|Bacilli	KL	COG1199 Rad3-related DNA helicases	ypvA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
HKD3_k127_137811_3	574376.BAMA_14275	1.598e-207	649.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus	91061|Bacilli	L	Belongs to the methyltransferase superfamily	ypsC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
HKD3_k127_137811_7	574375.BAGA_16450	4.396e-43	159.0	COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,1ZQAY@1386|Bacillus	91061|Bacilli	D	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation	gpsB	-	-	-	-	-	-	-	-	-	-	-	DivIVA
HKD3_k127_1398479_2	1169144.KB910925_gene158	3.154e-119	384.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,1ZCZW@1386|Bacillus	91061|Bacilli	C	Menaquinol-cytochrome c reductase cytochrome b c subunit	qcrC	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrome_CBB3
HKD3_k127_1398479_1	1169144.KB910925_gene159	1.035e-141	450.0	COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,4H9XV@91061|Bacilli,1ZB3U@1386|Bacillus	91061|Bacilli	C	COG1290 Cytochrome b subunit of the bc complex	qcrB	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
HKD3_k127_1398479_4	1396.DJ87_3156	4.432e-92	304.0	COG0723@1|root,COG0723@2|Bacteria,1TQUH@1239|Firmicutes,4HBX1@91061|Bacilli,1ZFNX@1386|Bacillus	91061|Bacilli	C	Menaquinol-cytochrome c reductase	qcrA	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CytB6-F_Fe-S,Rieske
HKD3_k127_1398479_3	574375.BAGA_16665	5.894e-98	321.0	COG5582@1|root,COG5582@2|Bacteria,1V5KV@1239|Firmicutes,4HEE0@91061|Bacilli,1ZB4J@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0302 family	ypiB	-	-	-	-	-	-	-	-	-	-	-	IDEAL,UPF0302
HKD3_k127_1398479_0	315749.Bcer98_1243	1.963e-167	536.0	COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	ypiA	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
HKD3_k127_1398479_5	1405.DJ92_4166	6.743e-23	100.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,1ZC9C@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD3_k127_1411416_3	1169144.KB910962_gene3019	1.852e-41	153.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,1ZFS0@1386|Bacillus	91061|Bacilli	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HKD3_k127_1411416_4	1405.DJ92_1666	2.084e-29	117.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,1ZFS0@1386|Bacillus	91061|Bacilli	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HKD3_k127_1411416_0	574376.BAMA_02445	7.976e-190	597.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapB	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_1411416_2	1169144.KB910962_gene3016	1.723e-75	258.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,1ZFSI@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
HKD3_k127_1411416_1	1169144.KB910962_gene3015	7.977e-82	277.0	COG1971@1|root,COG1971@2|Bacteria,1V4BC@1239|Firmicutes,4HH29@91061|Bacilli,1ZCPR@1386|Bacillus	91061|Bacilli	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD3_k127_1418898_5	315730.BcerKBAB4_1349	1.193e-34	134.0	COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,1ZBV1@1386|Bacillus	91061|Bacilli	H	Belongs to the precorrin methyltransferase family	cobA	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15610	TP_methylase
HKD3_k127_1418898_6	574376.BAMA_13615	5.903e-19	91.0	2ESX5@1|root,33KFH@2|Bacteria,1VMXQ@1239|Firmicutes,4HRVM@91061|Bacilli,1ZIYT@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3906
HKD3_k127_1418898_0	315749.Bcer98_1146	7.281e-276	855.0	COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,4HBEX@91061|Bacilli,1ZBHT@1386|Bacillus	91061|Bacilli	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	nirA	-	1.7.7.1	ko:K00366	ko00910,ko01120,map00910,map01120	M00531	R00790	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HKD3_k127_1418898_4	574376.BAMA_13605	3.486e-94	312.0	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,1ZBCZ@1386|Bacillus	91061|Bacilli	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
HKD3_k127_1418898_1	574375.BAGA_06920	5.002e-193	607.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,1ZCB4@1386|Bacillus	91061|Bacilli	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
HKD3_k127_1418898_2	420246.GTNG_0388	7.215e-108	359.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,1WG1Q@129337|Geobacillus	91061|Bacilli	P	Phosphate transporter family	cysP	-	-	ko:K16331	-	-	-	-	ko00000,ko02000	2.A.20.4	-	-	PHO4
HKD3_k127_1418898_3	1396.DJ87_3256	2.007e-105	345.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,1ZCBJ@1386|Bacillus	91061|Bacilli	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15570	PAPS_reduct
HKD3_k127_1423005_5	1169144.KB910928_gene1909	1.036e-126	408.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,1ZBXN@1386|Bacillus	91061|Bacilli	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
HKD3_k127_1423005_7	315749.Bcer98_3201	1.357e-93	311.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1ZFJM@1386|Bacillus	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HKD3_k127_1423005_9	1169144.KB910928_gene1907	2.039e-62	218.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,1ZH0K@1386|Bacillus	91061|Bacilli	S	Phosphoesterase	ysnB	GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD3_k127_1423005_10	1449063.JMLS01000016_gene953	5.429e-21	93.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1423005_6	665952.HMPREF1015_02687	1.233e-112	395.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	epr	GO:0005575,GO:0005576	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,SLH,fn3
HKD3_k127_1423005_4	1169144.KB910933_gene4242	1.606e-131	451.0	COG3103@1|root,COG3757@1|root,COG5632@1|root,COG3757@2|Bacteria,COG4991@2|Bacteria,COG5632@2|Bacteria,1V7SE@1239|Firmicutes,4HJQZ@91061|Bacilli,1ZINP@1386|Bacillus	91061|Bacilli	M	Glycosyl hydrolases family 25	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
HKD3_k127_1423005_11	574375.BAGA_24585	4.425e-11	67.0	29TGB@1|root,30EPJ@2|Bacteria,1UCT6@1239|Firmicutes,4IP9F@91061|Bacilli,1ZPK3@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1423005_3	574375.BAGA_24590	2.075e-147	478.0	28I2X@1|root,2Z86W@2|Bacteria,1V196@1239|Firmicutes,4HU2W@91061|Bacilli,1ZC9S@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1423005_8	574376.BAMA_11220	5.079e-63	228.0	COG3118@1|root,COG3118@2|Bacteria,1VEXG@1239|Firmicutes,4HQMC@91061|Bacilli,1ZDM8@1386|Bacillus	91061|Bacilli	O	COG0457 FOG TPR repeat	ysoA	-	-	-	-	-	-	-	-	-	-	-	TPR_19
HKD3_k127_1423005_1	315749.Bcer98_3187	1.579e-200	631.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
HKD3_k127_1423005_0	315730.BcerKBAB4_4317	2.022e-242	753.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD3_k127_1423005_2	315730.BcerKBAB4_4316	1.241e-149	476.0	COG0470@1|root,COG1067@1|root,COG0470@2|Bacteria,COG1067@2|Bacteria,1TP2K@1239|Firmicutes,4HB6F@91061|Bacilli,1ZBW1@1386|Bacillus	91061|Bacilli	LO	Belongs to the peptidase S16 family	lonB	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA,Lon_C
HKD3_k127_1423471_4	1131730.BAVI_16352	2.925e-53	190.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus	91061|Bacilli	V	ABC transporter	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_1423471_3	1243664.CAVL020000028_gene41	3.763e-68	236.0	COG3467@1|root,COG3467@2|Bacteria,1V2CN@1239|Firmicutes,4HBSQ@91061|Bacilli,1ZGCZ@1386|Bacillus	91061|Bacilli	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
HKD3_k127_1423471_1	796606.BMMGA3_02270	7.89e-233	725.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus	91061|Bacilli	P	Ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,MCPsignal
HKD3_k127_1423471_5	1382315.JPOI01000001_gene2457	9.426e-51	183.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4IQWE@91061|Bacilli	91061|Bacilli	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HKD3_k127_1423471_2	272558.10173187	3.144e-73	256.0	2DG92@1|root,2ZUZX@2|Bacteria,1UQR3@1239|Firmicutes,4HHNR@91061|Bacilli,1ZKCU@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1423471_0	1449063.JMLS01000017_gene545	1.661e-270	857.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_4,PAS_9
HKD3_k127_144707_2	1033743.CAES01000007_gene2063	7.991e-29	118.0	COG1694@1|root,COG1694@2|Bacteria,1VHCR@1239|Firmicutes	1239|Firmicutes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
HKD3_k127_144707_1	574375.BAGA_10440	4.626e-68	239.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus	91061|Bacilli	M	effector of murein hydrolase	ywbG	-	-	-	-	-	-	-	-	-	-	-	LrgB
HKD3_k127_144707_3	1121091.AUMP01000014_gene3458	1.86e-24	106.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,4HNKZ@91061|Bacilli	91061|Bacilli	S	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins. When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a	cidA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
HKD3_k127_144707_0	1169144.KB910953_gene3142	8.079e-100	333.0	COG0583@1|root,COG0583@2|Bacteria,1V09U@1239|Firmicutes,4HCJT@91061|Bacilli,1ZBPK@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_1449211_3	1408254.T458_13480	1.326e-24	106.0	COG0526@1|root,COG0526@2|Bacteria,1VFUD@1239|Firmicutes,4HNQS@91061|Bacilli,26ZVG@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin	ydfQ	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD3_k127_1449211_1	1169144.KB910948_gene3610	3.659e-130	421.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1657,DUF421
HKD3_k127_1449211_4	1405.DJ92_2195	1.855e-21	95.0	2EPX8@1|root,33HHR@2|Bacteria,1VNSM@1239|Firmicutes,4HSCB@91061|Bacilli,1ZRYZ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1657)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1657
HKD3_k127_1449211_2	1405.DJ92_2194	5.513e-57	203.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,4HIW4@91061|Bacilli,1ZG67@1386|Bacillus	91061|Bacilli	S	stage V sporulation protein	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HKD3_k127_1449211_0	1169144.KB910948_gene3607	8.935e-138	440.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,4H9W9@91061|Bacilli,1ZAW8@1386|Bacillus	91061|Bacilli	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
HKD3_k127_1450805_5	1268072.PSAB_04035	1.904e-117	384.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,26VH3@186822|Paenibacillaceae	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_1450805_4	1268072.PSAB_04030	6.531e-130	421.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,4HCXX@91061|Bacilli,26SBJ@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_1450805_9	315749.Bcer98_0701	1.121e-77	272.0	COG4072@1|root,COG4072@2|Bacteria,1V1VN@1239|Firmicutes,4HG8P@91061|Bacilli,1ZFZY@1386|Bacillus	91061|Bacilli	S	Protein of unknown function C-terminal (DUF3324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3324,DUF916
HKD3_k127_1450805_21	1552123.EP57_05720	1.286e-15	85.0	COG4886@1|root,COG4886@2|Bacteria,1V9D9@1239|Firmicutes,4HJPY@91061|Bacilli,26JB9@186820|Listeriaceae	91061|Bacilli	S	WxL domain surface cell wall-binding	-	-	-	-	-	-	-	-	-	-	-	-	WxL
HKD3_k127_1450805_23	1497679.EP56_11870	2.576e-10	72.0	COG1404@1|root,COG1404@2|Bacteria,1UX74@1239|Firmicutes,4I2IP@91061|Bacilli,26M8D@186820|Listeriaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1450805_24	1265845.PWEIH_09738	2.345e-08	66.0	COG2911@1|root,COG2911@2|Bacteria,1UHPT@1239|Firmicutes,4IS5N@91061|Bacilli,26M1N@186820|Listeriaceae	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Gram_pos_anchor,YSIRK_signal
HKD3_k127_1450805_0	1501230.ET33_27125	4.599e-286	882.0	COG0579@1|root,COG0579@2|Bacteria,1TNZY@1239|Firmicutes,4H9PS@91061|Bacilli,26QFX@186822|Paenibacillaceae	91061|Bacilli	S	malate quinone oxidoreductase	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS12375	Mqo
HKD3_k127_1450805_7	1449063.JMLS01000007_gene3528	1.4e-80	291.0	COG3290@1|root,COG3290@2|Bacteria,1V8QQ@1239|Firmicutes,4IQ1G@91061|Bacilli,26SI4@186822|Paenibacillaceae	91061|Bacilli	T	Sensor_kinase_SpoOB-type, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,SPOB_a
HKD3_k127_1450805_6	1117379.BABA_12610	7.897e-107	350.0	COG4430@1|root,COG4430@2|Bacteria,1V41W@1239|Firmicutes,4HDKN@91061|Bacilli,1ZC25@1386|Bacillus	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
HKD3_k127_1450805_11	1347086.CCBA010000027_gene3526	3.509e-74	259.0	COG2064@1|root,COG2064@2|Bacteria,1V2T1@1239|Firmicutes,4IRDA@91061|Bacilli,1ZR4J@1386|Bacillus	91061|Bacilli	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
HKD3_k127_1450805_14	1347086.CCBA010000027_gene3527	5.195e-71	252.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,4HEEI@91061|Bacilli,1ZFBU@1386|Bacillus	91061|Bacilli	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HKD3_k127_1450805_3	1347086.CCBA010000027_gene3528	1.145e-215	681.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4HAQM@91061|Bacilli,1ZBDR@1386|Bacillus	91061|Bacilli	U	COG4962 Flp pilus assembly protein, ATPase CpaF	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
HKD3_k127_1450805_12	1385511.N783_03890	2.071e-73	256.0	COG0455@1|root,COG0455@2|Bacteria,1UMT9@1239|Firmicutes,4HJT8@91061|Bacilli	91061|Bacilli	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HKD3_k127_1450805_19	1385511.N783_03885	1.519e-26	117.0	COG3745@1|root,COG3745@2|Bacteria,1U41Y@1239|Firmicutes,4HQWU@91061|Bacilli	91061|Bacilli	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	-	-	-	-	-	-	-	-	-	RcpC,SAF
HKD3_k127_1450805_8	946235.CAER01000007_gene301	1.642e-80	278.0	COG4961@1|root,COG4961@2|Bacteria,1UJS8@1239|Firmicutes,4HGJ1@91061|Bacilli	91061|Bacilli	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
HKD3_k127_1450805_20	1123239.KB898627_gene3488	5.142e-20	96.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,4HNWE@91061|Bacilli	91061|Bacilli	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
HKD3_k127_1450805_16	1123239.KB898627_gene3489	7.769e-36	142.0	COG1989@1|root,COG1989@2|Bacteria,1VFC1@1239|Firmicutes,4HM9A@91061|Bacilli	91061|Bacilli	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
HKD3_k127_1450805_22	1347086.CCBA010000027_gene3534	1.079e-10	63.0	COG3847@1|root,COG3847@2|Bacteria,1TZYU@1239|Firmicutes,4HSDV@91061|Bacilli	91061|Bacilli	U	Flp/Fap pilin component	-	-	-	-	-	-	-	-	-	-	-	-	Flp_Fap
HKD3_k127_1450805_18	946235.CAER01000007_gene305	1.147e-29	121.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,4HRCB@91061|Bacilli	91061|Bacilli	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
HKD3_k127_1450805_13	1078085.HMPREF1210_02393	6.306e-73	248.0	293T3@1|root,2ZR8H@2|Bacteria,1V593@1239|Firmicutes,4HG8Q@91061|Bacilli,26F34@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
HKD3_k127_1450805_17	1002809.SSIL_2526	5.079e-35	134.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,26FRS@186818|Planococcaceae	91061|Bacilli	K	Transcriptional regulator	yozG	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
HKD3_k127_1450805_2	1078085.HMPREF1210_02395	2.948e-229	714.0	2CA5R@1|root,2Z81H@2|Bacteria,1UYYB@1239|Firmicutes,4HA7J@91061|Bacilli,26E2K@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
HKD3_k127_1450805_1	1384049.CD29_08130	5.69e-241	755.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,4HF0C@91061|Bacilli	91061|Bacilli	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
HKD3_k127_1450805_10	1174504.AJTN02000193_gene4139	2.346e-76	258.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,1ZFK3@1386|Bacillus	91061|Bacilli	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HKD3_k127_1450805_15	574375.BAGA_13570	4.14e-40	150.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	yyxA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_1471902_3	574376.BAMA_01120	7.341e-08	54.0	2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD3_k127_1471902_0	1405.DJ92_1450	1.591e-42	161.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,1ZEVR@1386|Bacillus	91061|Bacilli	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
HKD3_k127_1471902_4	574376.BAMA_01135	2.101e-07	55.0	COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli	91061|Bacilli	K	Competence transcription factor	-	-	-	ko:K02250	ko02024,map02024	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	ComK
HKD3_k127_148762_0	315749.Bcer98_1153	3.581e-211	663.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus	91061|Bacilli	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	iYO844.BSU10220	SDF
HKD3_k127_148762_1	224308.BSU19170	4.971e-128	417.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HB1P@91061|Bacilli,1ZQ9Y@1386|Bacillus	91061|Bacilli	V	peptidase S66	yocD	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD3_k127_148762_2	1169144.KB910929_gene1841	5.613e-48	178.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus	91061|Bacilli	D	peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD3_k127_149006_0	471223.GWCH70_1982	2.374e-144	490.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1WFHG@129337|Geobacillus	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,MHYT,PAS,PAS_3,PAS_4,PAS_9
HKD3_k127_1495373_4	260799.BAS4133	1.272e-68	236.0	2CH5D@1|root,2Z821@2|Bacteria,1TS45@1239|Firmicutes,4HCE9@91061|Bacilli,1ZAXP@1386|Bacillus	91061|Bacilli	S	Bacterial protein YqhG of unknown function	yqhG	-	-	-	-	-	-	-	-	-	-	-	YqhG
HKD3_k127_1495373_0	1169144.KB910946_gene3708	4.562e-279	865.0	COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4H9WB@91061|Bacilli,1ZAR5@1386|Bacillus	91061|Bacilli	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	yqhH	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
HKD3_k127_1495373_2	1169144.KB910946_gene3707	1.946e-175	557.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HKD3_k127_1495373_1	260799.BAS4130	3.955e-241	750.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1ZB0H@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
HKD3_k127_1495373_3	1033734.CAET01000066_gene2097	2.244e-156	496.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1ZATI@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
HKD3_k127_1526686_4	315749.Bcer98_2244	9.762e-172	544.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZBKK@1386|Bacillus	91061|Bacilli	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
HKD3_k127_1526686_5	665952.HMPREF1015_02194	2.799e-100	328.0	COG4647@1|root,COG4647@2|Bacteria,1TTB5@1239|Firmicutes,4HCXE@91061|Bacilli,1ZEXW@1386|Bacillus	91061|Bacilli	Q	Acetone carboxylase gamma subunit	-	-	6.4.1.6	ko:K10856	-	-	-	-	ko00000,ko01000	-	-	-	Acetone_carb_G
HKD3_k127_1526686_0	796606.BMMGA3_02525	0.0	1434.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli,1ZDFI@1386|Bacillus	91061|Bacilli	EQ	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit	-	-	6.4.1.6	ko:K10854	-	-	-	-	ko00000,ko01000	-	-	-	Hydantoinase_B
HKD3_k127_1526686_1	665952.HMPREF1015_02196	0.0	1315.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,1ZAQW@1386|Bacillus	91061|Bacilli	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	6.4.1.6	ko:K10855	-	-	-	-	ko00000,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
HKD3_k127_1526686_2	666686.B1NLA3E_12285	2.38e-263	827.0	COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,4HUF7@91061|Bacilli,1ZS1R@1386|Bacillus	91061|Bacilli	KQ	COG3284 Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
HKD3_k127_1526686_3	1340434.AXVA01000012_gene2932	2.768e-188	595.0	COG0477@1|root,COG2814@2|Bacteria,1TRXM@1239|Firmicutes,4HCK1@91061|Bacilli,1ZPZJ@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
HKD3_k127_1532888_13	1341151.ASZU01000019_gene1090	8.167e-10	68.0	COG4326@1|root,COG4326@2|Bacteria,1V42B@1239|Firmicutes,4HGSB@91061|Bacilli,27BQ6@186824|Thermoactinomycetaceae	91061|Bacilli	S	SpoOM protein	-	-	-	ko:K06377	-	-	-	-	ko00000	-	-	-	Spo0M
HKD3_k127_1532888_5	1211814.CAPG01000027_gene1048	6.253e-168	541.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,1ZAP7@1386|Bacillus	91061|Bacilli	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HKD3_k127_1532888_11	1405.DJ92_4038	8.263e-39	149.0	COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,4IR3D@91061|Bacilli,1ZRRA@1386|Bacillus	91061|Bacilli	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD3_k127_1532888_6	1121091.AUMP01000020_gene3696	9.183e-121	392.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli	91061|Bacilli	IQ	Catalyzes a key regulatory step in fatty acid biosynthesis	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_1532888_3	1405.DJ92_4040	1.741e-211	664.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZBJ9@1386|Bacillus	91061|Bacilli	P	Potassium	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HKD3_k127_1532888_12	1169144.KB910983_gene3455	1.548e-17	86.0	2E1D6@1|root,32WSH@2|Bacteria,1U9K4@1239|Firmicutes,4IJRG@91061|Bacilli,1ZKWA@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1532888_10	315749.Bcer98_1117	2.363e-46	173.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli	91061|Bacilli	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HKD3_k127_1532888_9	665959.HMPREF1013_01495	4.777e-66	235.0	COG0737@1|root,COG4990@1|root,COG0737@2|Bacteria,COG4990@2|Bacteria,1V6DF@1239|Firmicutes,4HVQI@91061|Bacilli,1ZPUU@1386|Bacillus	91061|Bacilli	F	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HKD3_k127_1532888_16	333138.LQ50_06240	4.682e-05	47.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HC7T@91061|Bacilli,1ZQE0@1386|Bacillus	91061|Bacilli	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_1532888_0	574376.BAMA_13465	2.288e-305	942.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,1ZASK@1386|Bacillus	91061|Bacilli	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ILVD_EDD
HKD3_k127_1532888_1	315730.BcerKBAB4_1319	1.043e-298	923.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,1ZB1D@1386|Bacillus	91061|Bacilli	E	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	iYO844.BSU28310	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD3_k127_1532888_7	1405.DJ92_4048	4.826e-82	275.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli,1ZFP3@1386|Bacillus	91061|Bacilli	E	Acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ACT,ACT_5,ALS_ss_C
HKD3_k127_1532888_4	1396.DJ87_3278	9.044e-180	566.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli,1ZCH5@1386|Bacillus	91061|Bacilli	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
HKD3_k127_1532888_2	574375.BAGA_06810	3.719e-244	762.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus	91061|Bacilli	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10690,iYO844.BSU28280	HMGL-like,LeuA_dimer
HKD3_k127_1532888_8	1169144.KB910983_gene3463	6.979e-69	236.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli,1ZB3Y@1386|Bacillus	91061|Bacilli	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU28270	Iso_dh
HKD3_k127_1536489_0	1444306.JFZC01000078_gene1860	1.167e-77	263.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli	91061|Bacilli	E	Component of the transport system for branched-chain amino acids	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
HKD3_k127_1536489_2	1132442.KB889752_gene3503	3.101e-66	229.0	COG2318@1|root,COG2318@2|Bacteria,1VCS4@1239|Firmicutes,4HM90@91061|Bacilli,1ZERV@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_1536489_3	1132442.KB889752_gene3502	0.0002207	45.0	COG3448@1|root,COG3448@2|Bacteria,1V4K3@1239|Firmicutes,4HH5F@91061|Bacilli,1ZFJ1@1386|Bacillus	91061|Bacilli	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
HKD3_k127_1536489_1	1132442.KB889752_gene3501	1.382e-74	254.0	COG5516@1|root,COG5516@2|Bacteria,1VN58@1239|Firmicutes,4HS14@91061|Bacilli,1ZFS8@1386|Bacillus	91061|Bacilli	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
HKD3_k127_1540664_0	1405.DJ92_983	4.216e-166	525.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1ZC3M@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_1540664_1	1169144.KB910924_gene458	6.866e-73	248.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,1ZGBF@1386|Bacillus	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HKD3_k127_1567097_5	1033734.CAET01000089_gene3693	3.498e-21	94.0	2E4EA@1|root,32Z9I@2|Bacteria,1VG12@1239|Firmicutes,4HPD2@91061|Bacilli,1ZHZG@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1567097_6	1121091.AUMP01000006_gene4105	1.192e-14	74.0	2DTBP@1|root,33JKJ@2|Bacteria,1VKDH@1239|Firmicutes,4I0AV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1567097_1	1169144.KB910935_gene2071	1.206e-145	468.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,1ZCJY@1386|Bacillus	91061|Bacilli	E	Belongs to the arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_1567097_3	634956.Geoth_0175	1.534e-117	383.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,1WF4H@129337|Geobacillus	91061|Bacilli	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HKD3_k127_1567097_2	1169144.KB910935_gene2069	2.12e-140	458.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
HKD3_k127_1567097_0	1169144.KB910935_gene2068	9.571e-249	772.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,1ZC74@1386|Bacillus	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD3_k127_1567097_4	574376.BAMA_07390	9.289e-96	315.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus	91061|Bacilli	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iSB619.SA_RS11245,iYO844.BSU01780	GATase_6,SIS
HKD3_k127_1567200_6	1273538.G159_01845	4.717e-24	101.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26E95@186818|Planococcaceae	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_1567200_5	1410668.JNKC01000004_gene176	4.163e-112	370.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,36DI6@31979|Clostridiaceae	186801|Clostridia	K	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_1567200_3	935836.JAEL01000010_gene3743	1.613e-206	644.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli,1ZB8Z@1386|Bacillus	91061|Bacilli	C	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD3_k127_1567200_0	1295642.H839_03621	2.122e-295	910.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1WFCW@129337|Geobacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	dhaS	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_1567200_4	935836.JAEL01000010_gene3748	4.524e-202	634.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,1ZBBG@1386|Bacillus	91061|Bacilli	C	alcohol dehydrogenase	dhaT	-	1.1.1.202	ko:K00086	ko00561,ko00640,map00561,map00640	-	R02377,R03119	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HKD3_k127_1567200_2	666686.B1NLA3E_10150	5.883e-236	740.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,4HDJQ@91061|Bacilli,1ZC7F@1386|Bacillus	91061|Bacilli	T	GAF domain	cckA	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
HKD3_k127_1567200_1	935836.JAEL01000010_gene3745	2.217e-238	745.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,4HCST@91061|Bacilli,1ZCPN@1386|Bacillus	91061|Bacilli	T	Sigma-54 interaction domain	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD3_k127_1567200_7	1356854.N007_13015	4.634e-15	74.0	COG3384@1|root,COG3384@2|Bacteria,1TSRZ@1239|Firmicutes,4HAAN@91061|Bacilli,279JE@186823|Alicyclobacillaceae	91061|Bacilli	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ligB1	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
HKD3_k127_1573077_0	1274524.BSONL12_18669	1.539e-231	722.0	COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HBJG@91061|Bacilli,1ZQ9U@1386|Bacillus	91061|Bacilli	G	PTS system sugar-specific permease component	gatC	-	-	ko:K20114	ko02060,map02060	M00807	R11171	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5	-	-	EIIC-GAT
HKD3_k127_1573077_3	1074451.CRL705_1264	1.769e-42	157.0	COG3414@1|root,COG3414@2|Bacteria,1VACD@1239|Firmicutes,4HKHR@91061|Bacilli,3F732@33958|Lactobacillaceae	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.204	ko:K20113	ko02060,map02060	M00807	R11171	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5	-	-	PTS_IIB
HKD3_k127_1573077_2	665952.HMPREF1015_01185	1.271e-48	178.0	COG1762@1|root,COG1762@2|Bacteria,1VBW9@1239|Firmicutes,4I3MM@91061|Bacilli,1ZKFG@1386|Bacillus	91061|Bacilli	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
HKD3_k127_1573077_1	1274524.BSONL12_18654	3.399e-99	330.0	COG1349@1|root,COG1349@2|Bacteria,1V3BP@1239|Firmicutes,4HG06@91061|Bacilli,1ZG64@1386|Bacillus	91061|Bacilli	K	DeoR C terminal sensor domain	lacR	-	-	ko:K02530	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HKD3_k127_1576091_11	1395513.P343_14525	1.375e-81	276.0	COG1280@1|root,COG1280@2|Bacteria,1TRT5@1239|Firmicutes,4HBDN@91061|Bacilli	91061|Bacilli	E	Lysine transporter LysE	ycgF3	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_1576091_18	1382304.JNIL01000001_gene2558	1.012e-26	117.0	COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HKD3_k127_1576091_4	562970.Btus_0254	1.517e-223	713.0	COG3511@1|root,COG3511@2|Bacteria,1V171@1239|Firmicutes,4HDVY@91061|Bacilli,2796D@186823|Alicyclobacillaceae	91061|Bacilli	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
HKD3_k127_1576091_14	1405.DJ92_4526	1.094e-53	190.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,4HM9M@91061|Bacilli,1ZHC7@1386|Bacillus	91061|Bacilli	K	transcriptional	arsR	-	-	ko:K03892,ko:K22043	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HKD3_k127_1576091_15	1295642.H839_08883	3.488e-50	181.0	2BJ9H@1|root,32DJ6@2|Bacteria,1U4B6@1239|Firmicutes,4IFP0@91061|Bacilli,1WHKK@129337|Geobacillus	91061|Bacilli	S	Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
HKD3_k127_1576091_2	1295642.H839_08878	1.954e-281	874.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,4HBKG@91061|Bacilli,1WH5B@129337|Geobacillus	91061|Bacilli	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
HKD3_k127_1576091_17	1405.DJ92_4531	2.917e-28	119.0	COG0316@1|root,COG0316@2|Bacteria,1UPUS@1239|Firmicutes,4IVB4@91061|Bacilli	91061|Bacilli	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
HKD3_k127_1576091_7	1461580.CCAS010000048_gene3522	5.765e-190	597.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,4HC8A@91061|Bacilli,1ZD7K@1386|Bacillus	91061|Bacilli	P	Arsenic resistance protein	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	iYO844.BSU25790	SBF
HKD3_k127_1576091_12	574375.BAGA_17040	2.224e-74	251.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,1ZFM2@1386|Bacillus	91061|Bacilli	T	Catalyzes the reduction of arsenate As(V) to arsenite As(III)	arsC	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD3_k127_1576091_6	1423321.AS29_19265	1.855e-203	638.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4HT1J@91061|Bacilli,1ZEGP@1386|Bacillus	91061|Bacilli	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
HKD3_k127_1576091_3	1157490.EL26_20830	1.966e-272	847.0	COG2060@1|root,COG2060@2|Bacteria,1TPDF@1239|Firmicutes,4HA0B@91061|Bacilli,277X6@186823|Alicyclobacillaceae	91061|Bacilli	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iSB619.SA_RS00490	KdpA
HKD3_k127_1576091_1	1122915.AUGY01000047_gene1457	0.0	1030.0	COG2216@1|root,COG2216@2|Bacteria,1TPV5@1239|Firmicutes,4HASV@91061|Bacilli,26RE5@186822|Paenibacillaceae	91061|Bacilli	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iSB619.SA_RS00495	E1-E2_ATPase,Hydrolase
HKD3_k127_1576091_13	1157490.EL26_20820	2.02e-59	211.0	COG2156@1|root,COG2156@2|Bacteria,1V4GE@1239|Firmicutes,4HHHD@91061|Bacilli,278H1@186823|Alicyclobacillaceae	91061|Bacilli	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
HKD3_k127_1576091_0	997296.PB1_06162	0.0	1052.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,4HCQ3@91061|Bacilli,1ZEBR@1386|Bacillus	91061|Bacilli	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,Usp
HKD3_k127_1576091_8	1034769.KB910518_gene5218	3.751e-158	512.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,1TRM6@1239|Firmicutes,4HF9R@91061|Bacilli,26VA0@186822|Paenibacillaceae	91061|Bacilli	P	C-terminal AAA-associated domain	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
HKD3_k127_1576091_5	1227352.C173_17441	2.213e-218	691.0	COG4986@1|root,COG4986@2|Bacteria,1TRRR@1239|Firmicutes,4HEN6@91061|Bacilli,26VEF@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD3_k127_1576091_10	1121091.AUMP01000001_gene403	8.28e-139	450.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli	91061|Bacilli	S	permease	yueF	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_1576091_9	1403313.AXBR01000005_gene1766	6.331e-149	488.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZFC6@1386|Bacillus	91061|Bacilli	EG	Bacillus/Clostridium GerA spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
HKD3_k127_1576091_16	545693.BMQ_1677	2.984e-37	149.0	2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZERK@1386|Bacillus	91061|Bacilli	S	Spore germination B3/ GerAC like, C-terminal	gerAC5	-	-	ko:K06297	-	-	-	-	ko00000	-	-	-	Spore_GerAC
HKD3_k127_1579569_1	315749.Bcer98_0124	2.004e-173	547.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,1ZCEG@1386|Bacillus	91061|Bacilli	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HKD3_k127_1579569_4	1169144.KB910959_gene4000	2.307e-114	371.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
HKD3_k127_1579569_14	1169144.KB910959_gene4001	0.0005787	45.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZBQI@1386|Bacillus	91061|Bacilli	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD3_k127_1579569_12	1169144.KB910959_gene4002	1.646e-38	144.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,1ZHWN@1386|Bacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HKD3_k127_1579569_13	340099.Teth39_0398	1.029e-16	79.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia,42HG1@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HKD3_k127_1579569_11	279010.BL01026	1.323e-61	213.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,1ZGAW@1386|Bacillus	91061|Bacilli	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HKD3_k127_1579569_9	1347086.CCBA010000014_gene679	2.831e-71	241.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,1ZFIU@1386|Bacillus	91061|Bacilli	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HKD3_k127_1579569_0	260799.BAS0137	2.033e-189	593.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,1ZBHX@1386|Bacillus	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HKD3_k127_1579569_10	1294265.JCM21738_3745	1.259e-62	217.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,1ZG80@1386|Bacillus	91061|Bacilli	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HKD3_k127_1579569_6	1380408.AVGH01000035_gene168	1.624e-96	323.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,21WE3@150247|Anoxybacillus	91061|Bacilli	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA1	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HKD3_k127_1579569_2	574375.BAGA_17230	3.936e-137	443.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,1ZBBK@1386|Bacillus	91061|Bacilli	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HKD3_k127_1579569_3	315730.BcerKBAB4_0136	2.813e-120	392.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,1ZBNS@1386|Bacillus	91061|Bacilli	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HKD3_k127_1579569_5	315730.BcerKBAB4_0137	5.441e-106	351.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1ZCC7@1386|Bacillus	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD3_k127_1579569_7	574376.BAMA_11335	2.315e-78	263.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,1ZFJA@1386|Bacillus	91061|Bacilli	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HKD3_k127_1579569_8	574375.BAGA_17210	1.073e-73	250.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,1ZG6R@1386|Bacillus	91061|Bacilli	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HKD3_k127_1580944_1	1405.DJ92_1377	1.926e-123	403.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	pbpA	-	-	ko:K21465	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD3_k127_1580944_0	1405.DJ92_1378	1.719e-183	582.0	COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
HKD3_k127_1580944_2	260799.BAS4177	1.487e-116	377.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus	91061|Bacilli	P	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD3_k127_158176_0	1403313.AXBR01000010_gene1178	3.382e-285	883.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HKD3_k127_158176_1	981383.AEWH01000024_gene2667	1.136e-60	211.0	COG1917@1|root,COG1917@2|Bacteria,1TSNR@1239|Firmicutes,4HENR@91061|Bacilli	91061|Bacilli	S	COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1
HKD3_k127_1661553_1	345219.Bcoa_2064	1.013e-151	486.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC7U@91061|Bacilli,1ZCS4@1386|Bacillus	91061|Bacilli	S	Phosphotransferase system, EIIC	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
HKD3_k127_1661553_3	1134474.O59_000431	6.805e-58	219.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1FHZ4@10|Cellvibrio	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
HKD3_k127_1661553_0	1321778.HMPREF1982_01277	3.914e-180	574.0	COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,248C7@186801|Clostridia,26CPC@186813|unclassified Clostridiales	186801|Clostridia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_1661553_2	1132442.KB889752_gene1824	3.751e-104	342.0	COG1215@1|root,COG1215@2|Bacteria,1TSD3@1239|Firmicutes,4HD23@91061|Bacilli,1ZFCB@1386|Bacillus	91061|Bacilli	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,Glycos_transf_2,PilZ
HKD3_k127_16713_4	545693.BMQ_2613	3.766e-94	311.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,4HB4V@91061|Bacilli,1ZEKA@1386|Bacillus	91061|Bacilli	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiL	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HKD3_k127_16713_3	666686.B1NLA3E_01925	8.27e-138	441.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,4HBN5@91061|Bacilli,1ZC10@1386|Bacillus	91061|Bacilli	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiF	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HKD3_k127_16713_1	545693.BMQ_2611	1.104e-185	586.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,4HAX7@91061|Bacilli,1ZDUC@1386|Bacillus	91061|Bacilli	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid
HKD3_k127_16713_0	666686.B1NLA3E_01935	5.951e-232	725.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,4H9SN@91061|Bacilli,1ZBFV@1386|Bacillus	91061|Bacilli	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
HKD3_k127_16713_2	666686.B1NLA3E_01940	4.756e-183	576.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,4HAQW@91061|Bacilli,1ZDAN@1386|Bacillus	91061|Bacilli	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
HKD3_k127_1713329_3	1169144.KB910928_gene1890	7.981e-57	206.0	COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus	91061|Bacilli	M	stage VI sporulation protein D	spoVID	GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117	-	ko:K06417	-	-	-	-	ko00000	-	-	-	LysM
HKD3_k127_1713329_2	1169144.KB910928_gene1889	9.184e-137	443.0	COG2334@1|root,COG2334@2|Bacteria,1UR1J@1239|Firmicutes,4HFR5@91061|Bacilli,1ZQHQ@1386|Bacillus	91061|Bacilli	S	Spore coat protein	ysxE	-	-	-	-	-	-	-	-	-	-	-	APH
HKD3_k127_1713329_0	545693.BMQ_4677	0.0	1534.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD3_k127_1713329_1	1405.DJ92_1554	2.192e-181	576.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,1ZAWN@1386|Bacillus	91061|Bacilli	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD3_k127_1713329_4	1169144.KB910928_gene1885	5.428e-22	105.0	2EH4E@1|root,33AWD@2|Bacteria,1VKBC@1239|Firmicutes,4HREV@91061|Bacilli,1ZJDB@1386|Bacillus	91061|Bacilli	-	-	-	-	-	ko:K06380	-	-	-	-	ko00000	-	-	-	SPOR
HKD3_k127_1728709_2	1169144.KB910928_gene1966	7.27e-38	143.0	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,1ZHZX@1386|Bacillus	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HKD3_k127_1728709_1	315749.Bcer98_3242	7.689e-58	205.0	COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,1ZDGZ@1386|Bacillus	91061|Bacilli	S	membrane protein, required for colicin V production	yshB	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
HKD3_k127_1728709_0	315749.Bcer98_3241	1.064e-270	842.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus	91061|Bacilli	L	COG1796 DNA polymerase IV (family X)	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
HKD3_k127_174494_0	574375.BAGA_26455	1.106e-294	915.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus	91061|Bacilli	E	glutamate synthase	gltA2	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD3_k127_174494_1	315749.Bcer98_0453	1.255e-234	730.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HBDZ@91061|Bacilli,1ZB74@1386|Bacillus	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	gsaB	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU08710	Aminotran_3
HKD3_k127_174494_2	1169144.KB910940_gene2569	1.239e-179	566.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,1ZBGB@1386|Bacillus	91061|Bacilli	S	transport system, ATPase component	drrA1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_174494_4	315749.Bcer98_0455	2.149e-131	423.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,1ZBKH@1386|Bacillus	91061|Bacilli	S	ABC transporter (permease)	M1-956	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
HKD3_k127_174494_3	198094.BA_0534	1.126e-135	437.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,1ZAWY@1386|Bacillus	91061|Bacilli	S	transport system, permease component	M1-957	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
HKD3_k127_174494_8	315749.Bcer98_0457	5.251e-38	147.0	COG1226@1|root,32UM6@2|Bacteria,1VC22@1239|Firmicutes,4HMGA@91061|Bacilli,1ZJ2P@1386|Bacillus	91061|Bacilli	P	Ion transport	-	-	-	ko:K08713	-	-	-	-	ko00000,ko02000	1.A.1.29.1	-	-	Ion_trans_2
HKD3_k127_174494_6	398511.BpOF4_10905	3.418e-67	233.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli,1ZFKU@1386|Bacillus	91061|Bacilli	O	Peroxiredoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD3_k127_174494_5	574375.BAGA_26490	5.772e-76	257.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,1ZFKE@1386|Bacillus	91061|Bacilli	P	Belongs to the Fur family	perR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD3_k127_174494_7	1169144.KB910940_gene2575	9.612e-47	170.0	2C1CK@1|root,313Y4@2|Bacteria,1V6FR@1239|Firmicutes,4HIGI@91061|Bacilli,1ZGXQ@1386|Bacillus	91061|Bacilli	S	UPF0295 protein	ygzB	-	-	-	-	-	-	-	-	-	-	-	DUF2614
HKD3_k127_174494_9	441769.ABFU01000135_gene3474	3.063e-13	69.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes,4I01W@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_177144_0	1169144.KB910968_gene3380	6.777e-180	565.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus	91061|Bacilli	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
HKD3_k127_177144_1	315730.BcerKBAB4_4141	1.569e-50	181.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus	91061|Bacilli	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
HKD3_k127_1779178_14	1169144.KB910924_gene520	4.586e-32	127.0	2E309@1|root,32TAR@2|Bacteria,1VBNE@1239|Firmicutes,4HM33@91061|Bacilli,1ZI2F@1386|Bacillus	91061|Bacilli	S	YlaH-like protein	ylaH	-	-	-	-	-	-	-	-	-	-	-	YlaH
HKD3_k127_1779178_12	1405.DJ92_1046	5.728e-34	132.0	2E3PV@1|root,32YMW@2|Bacteria,1VFBQ@1239|Firmicutes,4HPVP@91061|Bacilli,1ZIJ9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1779178_15	1444310.JANV01000090_gene4120	4.356e-24	102.0	COG4896@1|root,COG4896@2|Bacteria,1VFMW@1239|Firmicutes,4HNPM@91061|Bacilli,1ZIXV@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ylaI	-	-	-	-	-	-	-	-	-	-	-	DUF2197
HKD3_k127_1779178_9	574375.BAGA_01190	5.789e-66	228.0	COG1853@1|root,COG1853@2|Bacteria,1V950@1239|Firmicutes,4IS92@91061|Bacilli,1ZS3A@1386|Bacillus	91061|Bacilli	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HKD3_k127_1779178_2	1169144.KB910924_gene516	1.84e-257	797.0	COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus	91061|Bacilli	T	ATPase related to phosphate starvation-inducible protein PhoH	ylaK	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
HKD3_k127_1779178_10	1405.DJ92_1042	1.095e-64	225.0	COG2041@1|root,COG2041@2|Bacteria,1V1EZ@1239|Firmicutes,4HIWI@91061|Bacilli,1ZDPV@1386|Bacillus	91061|Bacilli	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	ylaL	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_1779178_11	1444310.JANV01000090_gene4115	5.16e-45	167.0	COG4838@1|root,COG4838@2|Bacteria,1VAXB@1239|Firmicutes,4HKIX@91061|Bacilli,1ZI2B@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0358 family	ylaN	-	-	-	-	-	-	-	-	-	-	-	DUF1507
HKD3_k127_1779178_6	1169144.KB910924_gene513	1.501e-124	410.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBDZ@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD3_k127_1779178_0	1169144.KB910924_gene512	0.0	1988.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus	91061|Bacilli	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
HKD3_k127_1779178_5	315749.Bcer98_2648	1.642e-132	428.0	COG1612@1|root,COG1612@2|Bacteria,1TR4W@1239|Firmicutes,4HC12@91061|Bacilli,1ZC0K@1386|Bacillus	91061|Bacilli	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	GO:0000003,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0019954,GO:0022607,GO:0030436,GO:0032502,GO:0034622,GO:0043933,GO:0043934,GO:0044085,GO:0065003,GO:0071840	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	iSB619.SA_RS05460,iYO844.BSU14870	COX15-CtaA
HKD3_k127_1779178_4	1396.DJ87_917	1.057e-145	468.0	COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus	91061|Bacilli	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iSB619.SA_RS05465	UbiA
HKD3_k127_1779178_3	1396.DJ87_918	2.061e-169	537.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus	91061|Bacilli	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
HKD3_k127_1779178_1	1169144.KB910924_gene508	0.0	1049.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus	91061|Bacilli	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HKD3_k127_1779178_7	265729.GS18_0204060	1.457e-104	343.0	COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HAHK@91061|Bacilli,1ZBVD@1386|Bacillus	91061|Bacilli	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HKD3_k127_1779178_13	315749.Bcer98_2643	1.093e-32	129.0	COG3125@1|root,COG3125@2|Bacteria,1V855@1239|Firmicutes,4HMYQ@91061|Bacilli,1ZQRW@1386|Bacillus	91061|Bacilli	C	Cytochrome c oxidase subunit	ctaF	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
HKD3_k127_1779178_8	574375.BAGA_01130	7.578e-89	298.0	COG3336@1|root,COG3336@2|Bacteria,1TQFK@1239|Firmicutes,4H9WN@91061|Bacilli,1ZBC8@1386|Bacillus	91061|Bacilli	S	cytochrome c oxidase	ctaG	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
HKD3_k127_180831_6	198094.BA_2035	6.01e-80	271.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HKD3_k127_180831_2	198094.BA_2021	2.883e-136	440.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HARN@91061|Bacilli,1ZCRT@1386|Bacillus	91061|Bacilli	S	Cobalamin biosynthesis protein CobW	yjiA	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HKD3_k127_180831_3	1307436.PBF_01890	1.15e-125	415.0	COG0477@1|root,COG2814@2|Bacteria,1TSR2@1239|Firmicutes,4HD8G@91061|Bacilli,1ZCGV@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD3_k127_180831_7	1396.DJ87_2813	2.599e-56	199.0	2BYAA@1|root,34AZI@2|Bacteria,1W0PC@1239|Firmicutes,4HY15@91061|Bacilli,1ZK82@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3939)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3939
HKD3_k127_180831_0	315730.BcerKBAB4_3482	3.92e-285	886.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus	91061|Bacilli	GT	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HKD3_k127_180831_4	1211814.CAPG01000074_gene3521	3.623e-113	373.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,1ZB76@1386|Bacillus	91061|Bacilli	G	Belongs to the carbohydrate kinase PfkB family	pfkB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iYO844.BSU14390	PfkB
HKD3_k127_180831_5	315749.Bcer98_2396	2.974e-92	309.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,1ZBIR@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HKD3_k127_180831_1	1169144.KB911020_gene3337	3.284e-151	484.0	COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,4HBYW@91061|Bacilli,1ZAX1@1386|Bacillus	91061|Bacilli	S	membrane	ykvI	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
HKD3_k127_182777_11	1196029.ALIM01000030_gene870	8.207e-114	370.0	COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli,1ZDYN@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_182777_9	1117379.BABA_04774	1.759e-142	463.0	COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli,1ZBNV@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_182777_0	1169144.KB910948_gene3603	0.0	1033.0	COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,1ZEZ8@1386|Bacillus	91061|Bacilli	E	Amino acid permease	ydaO1	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD3_k127_182777_15	1405.DJ92_3178	2.819e-45	175.0	2ASSK@1|root,31I7S@2|Bacteria,1V7RU@1239|Firmicutes,4HJ2S@91061|Bacilli,1ZDBW@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_182777_17	1169144.KB911011_gene1003	1.623e-35	139.0	COG0789@1|root,COG0789@2|Bacteria,1VHZ2@1239|Firmicutes,4HMJ6@91061|Bacilli,1ZHVY@1386|Bacillus	91061|Bacilli	K	transcriptional	cueR	-	-	ko:K11923	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
HKD3_k127_182777_4	315749.Bcer98_2138	4.314e-221	691.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus	91061|Bacilli	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_182777_3	1461580.CCAS010000027_gene2618	2.476e-248	773.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus	91061|Bacilli	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
HKD3_k127_182777_13	1121091.AUMP01000056_gene3335	2.186e-49	181.0	2ED12@1|root,336Y0@2|Bacteria,1VHX4@1239|Firmicutes,4HR8Q@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PT-TG
HKD3_k127_182777_20	1169144.KB910941_gene2700	1.1e-16	82.0	29QUB@1|root,30BUD@2|Bacteria,1U8P6@1239|Firmicutes,4IIM9@91061|Bacilli,1ZNT0@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_182777_6	1169144.KB910941_gene2701	2.16e-165	530.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,4HNSC@91061|Bacilli,1ZQYK@1386|Bacillus	91061|Bacilli	V	resistance. Protein	vanW	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
HKD3_k127_182777_10	1169144.KB910941_gene2702	3.99e-121	397.0	COG1316@1|root,COG1316@2|Bacteria,1TQ9C@1239|Firmicutes,4HB29@91061|Bacilli,1ZB6K@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ywtF_2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD3_k127_182777_12	574375.BAGA_25075	1.542e-53	190.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ywkD	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD3_k127_182777_5	1169144.KB910941_gene2704	6.604e-196	619.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus	91061|Bacilli	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD3_k127_182777_7	574375.BAGA_09865	2.521e-159	510.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HBTP@91061|Bacilli,1ZATT@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	ydbM	-	-	-	-	-	-	-	-	-	-	iYO844.BSU04520	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_182777_2	1297581.H919_04649	1.069e-256	800.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli	91061|Bacilli	P	Pyridine nucleotide-disulfide oxidoreductase	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HKD3_k127_182777_14	545693.BMQ_4729	2.917e-46	168.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,1ZGXM@1386|Bacillus	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD3_k127_182777_16	574376.BAMA_07040	9.053e-41	153.0	COG0640@1|root,COG0640@2|Bacteria,1VF14@1239|Firmicutes,4IPKU@91061|Bacilli,1ZNBE@1386|Bacillus	91061|Bacilli	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD3_k127_182777_18	1405.DJ92_3374	1.763e-33	131.0	COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli,1ZHTP@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yrkD	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
HKD3_k127_182777_19	1347086.CCBA010000039_gene4778	2.704e-31	126.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZH5X@1386|Bacillus	91061|Bacilli	P	Sulfurtransferase	ytwF	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_182777_21	260799.BAS0579	1.678e-12	69.0	2DR1T@1|root,339TA@2|Bacteria,1VKWG@1239|Firmicutes	1239|Firmicutes	S	Small acid-soluble spore	sspH	-	-	ko:K06425	-	-	-	-	ko00000	-	-	-	SspH
HKD3_k127_182777_1	574376.BAMA_07075	5.536e-262	820.0	COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HCPJ@91061|Bacilli,1ZD6R@1386|Bacillus	91061|Bacilli	P	Von Willebrand factor	yojO	-	-	-	-	-	-	-	-	-	-	-	CobT_C,VWA
HKD3_k127_182777_8	1169144.KB910945_gene2431	3.474e-146	467.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,4HBG4@91061|Bacilli,1ZAT6@1386|Bacillus	91061|Bacilli	S	ATPase family associated with various cellular activities (AAA)	yojN	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
HKD3_k127_1855789_0	1118054.CAGW01000101_gene4735	5.584e-210	658.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,26QUB@186822|Paenibacillaceae	91061|Bacilli	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	aadAT	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HKD3_k127_1855789_1	1122915.AUGY01000055_gene495	3.611e-151	492.0	COG0477@1|root,COG0477@2|Bacteria,1UNMW@1239|Firmicutes,4ISTJ@91061|Bacilli,277BN@186822|Paenibacillaceae	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD3_k127_1855789_2	221109.22778965	3.324e-14	72.0	COG2059@1|root,COG2059@2|Bacteria,1TSKA@1239|Firmicutes,4HBB1@91061|Bacilli,23J17@182709|Oceanobacillus	91061|Bacilli	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD3_k127_19438_0	1169144.KB910936_gene1238	1.542e-242	751.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,1ZBFJ@1386|Bacillus	91061|Bacilli	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HKD3_k127_19438_2	315730.BcerKBAB4_4265	7.11e-183	576.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,1ZB71@1386|Bacillus	91061|Bacilli	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD3_k127_19438_8	545693.BMQ_4642	1.697e-19	89.0	2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,4HPC6@91061|Bacilli,1ZJ6M@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2905)	yrzS	-	-	-	-	-	-	-	-	-	-	-	DUF2905
HKD3_k127_19438_1	574376.BAMA_21550	1.482e-185	583.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,1ZC5A@1386|Bacillus	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HKD3_k127_19438_4	315730.BcerKBAB4_4268	6.191e-91	303.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,1ZBJT@1386|Bacillus	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HKD3_k127_19438_5	1405.DJ92_1522	1.443e-56	201.0	2DGQY@1|root,32U7R@2|Bacteria,1V83A@1239|Firmicutes,4HKRI@91061|Bacilli,1ZH9Y@1386|Bacillus	91061|Bacilli	S	BofC C-terminal domain	bofC	-	-	ko:K06318	-	-	-	-	ko00000	-	-	-	BOFC_N,BofC_C
HKD3_k127_19438_6	1169144.KB910936_gene1231	2.934e-45	173.0	2C7CE@1|root,33IXM@2|Bacteria,1VQ1J@1239|Firmicutes,4HSYK@91061|Bacilli	91061|Bacilli	S	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)	-	-	-	ko:K06345	-	-	-	-	ko00000	-	-	-	Spore_YhcN_YlaJ
HKD3_k127_19438_3	666686.B1NLA3E_16590	4.552e-131	421.0	COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,1ZBM2@1386|Bacillus	91061|Bacilli	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	GO:0000003,GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019954,GO:0030436,GO:0032502,GO:0034641,GO:0034654,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
HKD3_k127_19438_7	997296.PB1_15709	2.242e-43	171.0	COG0510@1|root,COG0510@2|Bacteria,1VB8C@1239|Firmicutes,4HNC9@91061|Bacilli,1ZAQ0@1386|Bacillus	91061|Bacilli	M	choline kinase involved in LPS biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	APH
HKD3_k127_19505_3	1396.DJ87_491	4.184e-86	289.0	COG0500@1|root,COG2226@2|Bacteria,1V3T6@1239|Firmicutes,4HHF1@91061|Bacilli,1ZFN7@1386|Bacillus	91061|Bacilli	Q	Could be a S-adenosyl-L-methionine-dependent methyltransferase	yrrT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00609	R10404	RC00003	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
HKD3_k127_19505_2	1169144.KB910936_gene1285	1.302e-119	388.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,1ZB7T@1386|Bacillus	91061|Bacilli	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_19505_0	1405.DJ92_1470	1.993e-161	512.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZD93@1386|Bacillus	91061|Bacilli	E	Cysteine synthase	mccA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.134,2.5.1.47	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00609	R00897,R03601,R04859,R10305	RC00020,RC00069,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02385	PALP
HKD3_k127_19505_1	1396.DJ87_494	2.093e-142	454.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	mccB	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27250	Cys_Met_Meta_PP
HKD3_k127_198340_1	574376.BAMA_17465	1.439e-114	374.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD3_k127_198340_0	1169144.KB910927_gene1323	1.033e-144	461.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,1ZAQP@1386|Bacillus	91061|Bacilli	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS04895	NAD_kinase
HKD3_k127_198340_3	574375.BAGA_21195	4.992e-108	352.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,1ZBM8@1386|Bacillus	91061|Bacilli	S	GTP pyrophosphokinase	yjbM	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HKD3_k127_198340_5	315749.Bcer98_0912	1.871e-62	220.0	COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1ZH0U@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yjbK	-	-	-	-	-	-	-	-	-	-	-	CYTH
HKD3_k127_198340_4	315730.BcerKBAB4_1105	1.639e-64	222.0	COG2346@1|root,COG2346@2|Bacteria,1V6JN@1239|Firmicutes,4HHQG@91061|Bacilli,1ZG81@1386|Bacillus	91061|Bacilli	S	COG2346 Truncated hemoglobins	yjbI	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD3_k127_198340_2	1405.DJ92_3812	5.674e-114	374.0	COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,1ZATS@1386|Bacillus	91061|Bacilli	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	yjbH	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_5
HKD3_k127_2045485_1	1169144.KB910942_gene2640	9.898e-164	522.0	COG3853@1|root,COG3853@2|Bacteria,1V0WJ@1239|Firmicutes,4HDEB@91061|Bacilli	91061|Bacilli	P	Belongs to the TelA family	telA	-	-	-	-	-	-	-	-	-	-	-	TelA
HKD3_k127_2045485_2	1169144.KB910942_gene2639	1.72e-70	248.0	29SKJ@1|root,30DRW@2|Bacteria,1UBMB@1239|Firmicutes,4IN1M@91061|Bacilli,1ZMJA@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF3974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3974
HKD3_k127_2045485_0	1280390.CBQR020000102_gene2692	0.0	1188.0	COG1470@1|root,COG2374@1|root,COG4085@1|root,COG1470@2|Bacteria,COG2374@2|Bacteria,COG4085@2|Bacteria,1TSI3@1239|Firmicutes,4HAWG@91061|Bacilli,26QIC@186822|Paenibacillaceae	91061|Bacilli	E	lipolytic protein G-D-S-L family	M1-554	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
HKD3_k127_2125074_1	1169144.KB910925_gene141	1.795e-207	660.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
HKD3_k127_2125074_3	1169144.KB910925_gene140	2.405e-20	91.0	2E85E@1|root,332IZ@2|Bacteria,1VHMN@1239|Firmicutes,4HPYR@91061|Bacilli,1ZIUT@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4264)	ypmA	-	-	-	-	-	-	-	-	-	-	-	DUF4264
HKD3_k127_2125074_2	1405.DJ92_4194	1.946e-46	172.0	COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,1ZFVJ@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ypmB	-	-	-	-	-	-	-	-	-	-	-	PepSY
HKD3_k127_2125074_0	491915.Aflv_1134	4.45e-246	763.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,21W5R@150247|Anoxybacillus	91061|Bacilli	J	tRNA synthetases class II (D, K and N)	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD3_k127_225890_1	1501230.ET33_16615	1.5e-134	431.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,26S40@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD3_k127_225890_3	574375.BAGA_11340	8.749e-35	136.0	COG2076@1|root,COG2076@2|Bacteria,1VEUF@1239|Firmicutes,4HM1T@91061|Bacilli,1ZI26@1386|Bacillus	91061|Bacilli	U	Small Multidrug Resistance protein	ebrA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K11814	-	M00710	-	-	ko00000,ko00002,ko02000	2.A.7.1.6	-	-	Multi_Drug_Res
HKD3_k127_225890_2	491915.Aflv_2024	4.541e-77	264.0	COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HFF9@91061|Bacilli,21WUJ@150247|Anoxybacillus	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD3_k127_225890_0	1405.DJ92_2986	1.939e-188	595.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus	91061|Bacilli	CE	COG0665 Glycine D-amino acid oxidases (deaminating)	yhfW	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
HKD3_k127_230151_4	1274374.CBLK010000003_gene3248	2.858e-22	98.0	COG1971@1|root,COG1971@2|Bacteria,1V9J8@1239|Firmicutes,4HJXD@91061|Bacilli,275FA@186822|Paenibacillaceae	91061|Bacilli	P	Putative manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD3_k127_230151_1	1174504.AJTN02000229_gene4403	1.625e-72	249.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,1ZAUV@1386|Bacillus	91061|Bacilli	K	AraC family transcriptional regulator	ydeE7	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
HKD3_k127_230151_5	1120973.AQXL01000125_gene3145	2.227e-17	83.0	2DDZM@1|root,2ZJYJ@2|Bacteria,1W2DM@1239|Firmicutes,4I0FT@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_230151_2	666686.B1NLA3E_09750	1.648e-65	228.0	COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,4HH71@91061|Bacilli,1ZEDJ@1386|Bacillus	91061|Bacilli	H	RibD C-terminal domain	ywjB	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD3_k127_230151_0	1123230.ARQJ01000031_gene2346	1.492e-113	376.0	COG1960@1|root,COG1960@2|Bacteria,1UXYJ@1239|Firmicutes,4HD52@91061|Bacilli	91061|Bacilli	I	acyl-CoA dehydrogenase	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2
HKD3_k127_230151_3	997346.HMPREF9374_2843	6.165e-51	183.0	COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,4HMGX@91061|Bacilli,27CEG@186824|Thermoactinomycetaceae	91061|Bacilli	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
HKD3_k127_240195_2	1033734.CAET01000079_gene3638	2.666e-45	166.0	COG1846@1|root,COG1846@2|Bacteria,1V3PS@1239|Firmicutes,4HFN6@91061|Bacilli,1ZFRK@1386|Bacillus	91061|Bacilli	K	transcriptional	yybA	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD3_k127_240195_1	1121091.AUMP01000031_gene1437	2.107e-264	820.0	COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli	91061|Bacilli	E	amino acid	lysP	-	-	ko:K11733	-	-	-	-	ko00000,ko02000	2.A.3.1.2	-	-	AA_permease
HKD3_k127_240195_0	1444310.JANV01000124_gene2955	2.372e-267	830.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,1ZBIP@1386|Bacillus	91061|Bacilli	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HKD3_k127_2442556_2	1405.DJ92_4474	8.432e-186	586.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus	91061|Bacilli	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	yvdB	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HKD3_k127_2442556_9	649747.HMPREF0083_00160	2.871e-45	167.0	COG0640@1|root,COG0640@2|Bacteria,1V6CU@1239|Firmicutes,4HJ7N@91061|Bacilli,26YN7@186822|Paenibacillaceae	91061|Bacilli	K	ArsR family transcriptional regulator	arsR9	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD3_k127_2442556_12	1347369.CCAD010000054_gene172	9.533e-11	64.0	2DKK1@1|root,309RW@2|Bacteria,1U5JZ@1239|Firmicutes,4IFAR@91061|Bacilli,1ZK2R@1386|Bacillus	91061|Bacilli	S	YqzL-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YqzL
HKD3_k127_2442556_5	1169144.KB910958_gene3940	2.986e-128	413.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,1ZAUA@1386|Bacillus	91061|Bacilli	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HKD3_k127_2442556_6	1169144.KB910958_gene3941	6.533e-112	365.0	COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,1ZB0P@1386|Bacillus	91061|Bacilli	K	CBS domain	ccpN	GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	CBS,HTH_11
HKD3_k127_2442556_4	574376.BAMA_22155	1.068e-141	452.0	COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,1ZBIT@1386|Bacillus	91061|Bacilli	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	yqfL	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
HKD3_k127_2442556_11	574376.BAMA_22160	5.421e-15	75.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,1ZFK7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0178 family	yqxD	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HKD3_k127_2442556_13	574376.BAMA_22160	3.578e-06	49.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,1ZFK7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0178 family	yqxD	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HKD3_k127_2442556_0	1396.DJ87_570	1.581e-245	771.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,1ZC16@1386|Bacillus	91061|Bacilli	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HKD3_k127_2442556_1	406124.ACPC01000019_gene3342	4.815e-211	659.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,1ZAV8@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_2442556_10	1396.DJ87_572	1.004e-38	147.0	COG2010@1|root,COG2010@2|Bacteria,1VDDX@1239|Firmicutes,4HN04@91061|Bacilli,1ZQNI@1386|Bacillus	91061|Bacilli	C	cytochrome	-	-	-	ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
HKD3_k127_2442556_7	574375.BAGA_03000	2.324e-88	297.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,1ZE5B@1386|Bacillus	91061|Bacilli	S	SAM-dependent methyltransferase	trmK	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TrmK
HKD3_k127_2442556_3	260799.BAS4191	6.641e-170	540.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus	91061|Bacilli	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
HKD3_k127_2442556_8	1169144.KB910968_gene3380	9.611e-53	186.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus	91061|Bacilli	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
HKD3_k127_2456819_24	1121091.AUMP01000027_gene769	5.058e-25	106.0	COG1136@1|root,COG1136@2|Bacteria,1V3HH@1239|Firmicutes,4HHE3@91061|Bacilli	91061|Bacilli	V	ABC transporter	-	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HKD3_k127_2456819_11	1121091.AUMP01000027_gene770	6.399e-115	375.0	COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli	91061|Bacilli	S	transport system, permease component	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
HKD3_k127_2456819_21	1169144.KB911021_gene3340	9.446e-42	155.0	COG4837@1|root,COG4837@2|Bacteria,1VA2D@1239|Firmicutes,4HKZN@91061|Bacilli,1ZI07@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuzD	-	-	-	-	-	-	-	-	-	-	-	DUF1462
HKD3_k127_2456819_22	1211814.CAPG01000076_gene3584	2.22e-37	141.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,1ZHTR@1386|Bacillus	91061|Bacilli	O	COG0694 Thioredoxin-like proteins and domains	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
HKD3_k127_2456819_9	574375.BAGA_11190	9.355e-142	456.0	COG2334@1|root,COG2334@2|Bacteria,1VEZ6@1239|Firmicutes,4HBAB@91061|Bacilli,1ZBAM@1386|Bacillus	91061|Bacilli	S	Spore coat protein	yutH	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2456819_15	1169144.KB910985_gene3787	2.842e-76	261.0	COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,1ZFQE@1386|Bacillus	91061|Bacilli	I	COG1267 Phosphatidylglycerophosphatase A and related proteins	yutG	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
HKD3_k127_2456819_18	268407.PWYN_01935	1.35e-48	179.0	COG1595@1|root,COG1595@2|Bacteria,1VB37@1239|Firmicutes,4HMZ2@91061|Bacilli,26RCC@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigY	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD3_k127_2456819_13	1211817.CCAT010000043_gene3400	1.451e-84	300.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,36E5R@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
HKD3_k127_2456819_12	394503.Ccel_0195	7.012e-109	357.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,36DUF@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_2456819_1	1396.DJ87_2980	6.207e-245	768.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZM81@1386|Bacillus	91061|Bacilli	S	Polysaccharide biosynthesis protein	mviN	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_2456819_10	1169144.KB910985_gene3794	1.305e-132	426.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,1ZB73@1386|Bacillus	91061|Bacilli	G	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro	nagD	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
HKD3_k127_2456819_17	1169144.KB910985_gene3796	5.773e-52	187.0	COG2445@1|root,COG2445@2|Bacteria,1V6HM@1239|Firmicutes,4HITV@91061|Bacilli,1ZGY2@1386|Bacillus	91061|Bacilli	S	Protein of unknown function DUF86	yutE	-	-	-	-	-	-	-	-	-	-	-	DUF86
HKD3_k127_2456819_4	315749.Bcer98_3560	8.839e-178	560.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZD19@1386|Bacillus	91061|Bacilli	G	fructose-1,6-bisphosphatase	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
HKD3_k127_2456819_23	315749.Bcer98_3561	1.379e-34	134.0	2CGTU@1|root,32Z9H@2|Bacteria,1VG36@1239|Firmicutes,4HNI4@91061|Bacilli,1ZI34@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3055)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3055
HKD3_k127_2456819_19	1169144.KB910985_gene3799	3.379e-47	170.0	COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,1ZHY5@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yutD	-	-	-	-	-	-	-	-	-	-	-	DUF1027
HKD3_k127_2456819_7	315749.Bcer98_3568	5.098e-166	525.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli,1ZB5D@1386|Bacillus	91061|Bacilli	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HKD3_k127_2456819_8	1169144.KB910985_gene3807	4.202e-163	518.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli,1ZAQT@1386|Bacillus	91061|Bacilli	M	Peptidase, M23	lytH	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD3_k127_2456819_5	1111479.AXAR01000005_gene450	1.11e-176	563.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,278YJ@186823|Alicyclobacillaceae	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	iYO844.BSU04360	Nramp
HKD3_k127_2456819_14	574375.BAGA_11365	5.603e-80	274.0	2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,4HIJV@91061|Bacilli,1ZQMM@1386|Bacillus	91061|Bacilli	S	sporulation protein	yunB	-	-	-	-	-	-	-	-	-	-	-	Spore_YunB
HKD3_k127_2456819_20	574376.BAMA_10970	2.105e-42	157.0	COG3377@1|root,COG3377@2|Bacteria,1VAP7@1239|Firmicutes,4HKBM@91061|Bacilli,1ZHYB@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1805)	yunC	-	-	-	-	-	-	-	-	-	-	-	DUF1805
HKD3_k127_2456819_3	1169144.KB910985_gene3810	1.516e-189	602.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1ZCJ8@1386|Bacillus	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yunD	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HKD3_k127_2456819_0	1169144.KB910995_gene3077	4.286e-293	900.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,1ZCDS@1386|Bacillus	91061|Bacilli	O	FeS cluster assembly	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
HKD3_k127_2456819_16	1034347.CAHJ01000065_gene3000	1.152e-71	244.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,1ZFQ8@1386|Bacillus	91061|Bacilli	C	COG0822 NifU homolog involved in Fe-S cluster formation	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HKD3_k127_2456819_2	260799.BAS4849	1.393e-232	723.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,1ZB79@1386|Bacillus	91061|Bacilli	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
HKD3_k127_2456819_6	1169144.KB910995_gene3074	1.413e-174	550.0	COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,1ZATY@1386|Bacillus	91061|Bacilli	O	assembly protein SufD	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HKD3_k127_2457493_11	1444309.JAQG01000087_gene2652	7.978e-75	252.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,26SK6@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
HKD3_k127_2457493_1	666686.B1NLA3E_11775	9.922e-215	670.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,1ZCAN@1386|Bacillus	91061|Bacilli	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HKD3_k127_2457493_2	1405.DJ92_457	8.933e-195	616.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,1ZBBN@1386|Bacillus	91061|Bacilli	P	Membrane	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	CitMHS
HKD3_k127_2457493_13	1169144.KB910984_gene3855	4.606e-53	188.0	COG2120@1|root,COG2120@2|Bacteria,1VA8Q@1239|Firmicutes,4HKMK@91061|Bacilli,1ZH30@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1806)	yojF	-	-	-	-	-	-	-	-	-	-	-	DUF1806
HKD3_k127_2457493_7	1405.DJ92_455	1.271e-104	343.0	COG2120@1|root,COG2120@2|Bacteria,1TPSJ@1239|Firmicutes,4HA2P@91061|Bacilli,1ZB3T@1386|Bacillus	91061|Bacilli	S	deacetylase	yojG	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
HKD3_k127_2457493_17	1123405.AUMM01000016_gene2435	3.537e-17	89.0	290PN@1|root,2ZNBW@2|Bacteria,1W39G@1239|Firmicutes,4I0Q9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2457493_5	1121935.AQXX01000119_gene4820	4.033e-132	448.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XH59@135619|Oceanospirillales	135619|Oceanospirillales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,PAS_9
HKD3_k127_2457493_12	574375.BAGA_10095	3.483e-70	241.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHFK@91061|Bacilli,1ZGGN@1386|Bacillus	91061|Bacilli	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ebsC	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HKD3_k127_2457493_8	1405.DJ92_299	2.452e-101	350.0	COG1657@1|root,COG1657@2|Bacteria,1UHRD@1239|Firmicutes,4IS77@91061|Bacilli,1ZRBR@1386|Bacillus	91061|Bacilli	I	cell wall anchor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,SLH
HKD3_k127_2457493_15	997346.HMPREF9374_0804	1.186e-27	121.0	COG1657@1|root,COG1657@2|Bacteria,1VBUR@1239|Firmicutes,4HMDS@91061|Bacilli	91061|Bacilli	I	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
HKD3_k127_2457493_10	315730.BcerKBAB4_3044	2.426e-82	283.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,4HDM2@91061|Bacilli,1ZGB2@1386|Bacillus	91061|Bacilli	P	cobalt transport	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HKD3_k127_2457493_0	1405.DJ92_296	1.08e-233	735.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,1ZD95@1386|Bacillus	91061|Bacilli	P	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HKD3_k127_2457493_9	198094.BA_3363	2.974e-92	309.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,4HFXY@91061|Bacilli,1ZFPV@1386|Bacillus	91061|Bacilli	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
HKD3_k127_2457493_19	649747.HMPREF0083_02127	2.503e-15	78.0	COG5460@1|root,COG5460@2|Bacteria,1VG76@1239|Firmicutes,4HNYG@91061|Bacilli,2701I@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
HKD3_k127_2457493_22	545693.BMQ_2136	0.0003133	43.0	COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes,4HA25@91061|Bacilli,1ZED4@1386|Bacillus	91061|Bacilli	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
HKD3_k127_2457493_18	1169144.KB910939_gene2840	2.021e-16	80.0	28ZQK@1|root,2ZMFJ@2|Bacteria,1W6R0@1239|Firmicutes,4IM86@91061|Bacilli,1ZJG6@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2457493_6	1304284.L21TH_1634	1.828e-123	402.0	COG2267@1|root,COG2267@2|Bacteria,1TSC4@1239|Firmicutes,24DBP@186801|Clostridia	186801|Clostridia	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD3_k127_2457493_16	1169144.KB910939_gene2830	5.342e-19	88.0	COG2155@1|root,COG2155@2|Bacteria,1UAUC@1239|Firmicutes,4IM76@91061|Bacilli,1ZJDJ@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF378)	-	-	-	-	-	-	-	-	-	-	-	-	DUF378
HKD3_k127_2457493_4	1298598.JCM21714_3097	4.223e-164	522.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,4706A@74385|Gracilibacillus	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD3_k127_2457493_3	574376.BAMA_08090	6.69e-181	573.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,1ZCBB@1386|Bacillus	91061|Bacilli	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT_4
HKD3_k127_2457493_14	1487923.DP73_12790	4.06e-32	128.0	COG0500@1|root,COG2226@2|Bacteria,1V261@1239|Firmicutes,24D1W@186801|Clostridia,263RZ@186807|Peptococcaceae	186801|Clostridia	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
HKD3_k127_2462071_15	406124.ACPC01000019_gene3163	4.446e-30	122.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,1ZB6M@1386|Bacillus	91061|Bacilli	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HKD3_k127_2462071_2	265729.GS18_0212230	8.801e-256	798.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZD5J@1386|Bacillus	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
HKD3_k127_2462071_14	1380408.AVGH01000015_gene1076	1.037e-42	172.0	COG2720@1|root,COG2720@2|Bacteria,1V0GP@1239|Firmicutes,4HEGI@91061|Bacilli,21VNC@150247|Anoxybacillus	91061|Bacilli	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,VanW
HKD3_k127_2462071_16	1267580.AF6_0657	8.485e-18	92.0	COG4967@1|root,COG4967@2|Bacteria,1V826@1239|Firmicutes,4HJMK@91061|Bacilli,21WT9@150247|Anoxybacillus	91061|Bacilli	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HKD3_k127_2462071_18	471223.GWCH70_2567	6.277e-13	76.0	COG4966@1|root,COG4966@2|Bacteria,1VK6P@1239|Firmicutes,4ISYM@91061|Bacilli,1WGCB@129337|Geobacillus	91061|Bacilli	NU	pilus assembly protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HKD3_k127_2462071_11	1423321.AS29_04540	3.167e-65	245.0	COG4726@1|root,COG4726@2|Bacteria,1UYJ5@1239|Firmicutes,4HFFJ@91061|Bacilli,1ZAY3@1386|Bacillus	91061|Bacilli	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2462071_17	1243664.CAVL020000005_gene397	6.142e-16	92.0	COG5492@1|root,COG5492@2|Bacteria,1TT7E@1239|Firmicutes,4HCCG@91061|Bacilli,1ZEXH@1386|Bacillus	91061|Bacilli	N	Domain of unknown function (DUF5057)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF5057
HKD3_k127_2462071_8	574375.BAGA_07570	9.13e-90	301.0	COG1556@1|root,COG1556@2|Bacteria,1UZAK@1239|Firmicutes,4HH3R@91061|Bacilli,1ZCX9@1386|Bacillus	91061|Bacilli	S	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source	lutC	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
HKD3_k127_2462071_1	574375.BAGA_07565	1.977e-268	830.0	COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,1ZCJB@1386|Bacillus	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
HKD3_k127_2462071_5	574375.BAGA_07560	2.261e-129	415.0	COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,1ZCUT@1386|Bacillus	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
HKD3_k127_2462071_7	1169144.KB910949_gene3579	5.416e-100	332.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1ZD1T@1386|Bacillus	91061|Bacilli	K	COG2186 Transcriptional regulators	yvfI	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
HKD3_k127_2462071_3	1169144.KB910949_gene3578	1.711e-197	626.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HANF@91061|Bacilli,1ZS27@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD3_k127_2462071_6	1396.DJ87_3377	3.762e-110	360.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZARN@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_2462071_9	1405.DJ92_3946	1.049e-89	305.0	COG3391@1|root,COG3391@2|Bacteria,1V3B0@1239|Firmicutes,4HG5S@91061|Bacilli,1ZAZ1@1386|Bacillus	91061|Bacilli	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2462071_13	1169144.KB910949_gene3575	2.599e-62	225.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus	91061|Bacilli	J	protein with SCP PR1 domains	ykwD	-	-	-	-	-	-	-	-	-	-	-	CAP
HKD3_k127_2462071_4	315730.BcerKBAB4_2226	1.172e-170	538.0	2BZ6P@1|root,2Z8AB@2|Bacteria,1TRT3@1239|Firmicutes,4HDZH@91061|Bacilli,1ZCVP@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF2935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2935
HKD3_k127_2462071_10	574375.BAGA_08225	3.148e-66	226.0	2DM7B@1|root,3212W@2|Bacteria,1V80J@1239|Firmicutes,4HK6G@91061|Bacilli,1ZHB0@1386|Bacillus	91061|Bacilli	S	YmaF family	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
HKD3_k127_2462071_0	1169144.KB910936_gene1288	0.0	1424.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,1ZBRJ@1386|Bacillus	91061|Bacilli	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00885	Aldedh,Fe-ADH
HKD3_k127_2462071_12	1396.DJ87_236	3.92e-65	228.0	COG1284@1|root,COG1284@2|Bacteria,1VB03@1239|Firmicutes,4HJQ8@91061|Bacilli	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
HKD3_k127_2462071_19	1347086.CCBA010000023_gene2327	7.42e-13	72.0	2EEF3@1|root,33893@2|Bacteria,1VEUA@1239|Firmicutes,4ICQN@91061|Bacilli,1ZBAX@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2501204_1	1396.DJ87_5190	1.697e-252	783.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus	91061|Bacilli	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iSB619.SA_RS11245,iYO844.BSU01780	GATase_6,SIS
HKD3_k127_2501204_3	935836.JAEL01000087_gene4682	2.167e-116	377.0	COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus	91061|Bacilli	S	Membrane	yyaS	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_2501204_10	935836.JAEL01000087_gene4683	1.689e-27	113.0	COG1846@1|root,COG1846@2|Bacteria,1V3PS@1239|Firmicutes,4HFN6@91061|Bacilli,1ZFRK@1386|Bacillus	91061|Bacilli	K	transcriptional	yybA	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD3_k127_2501204_4	1403313.AXBR01000015_gene2177	2.946e-98	321.0	COG0454@1|root,COG0456@2|Bacteria,1V1RG@1239|Firmicutes,4HFN7@91061|Bacilli,1ZDTF@1386|Bacillus	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	paiA	GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_2501204_11	1211035.CD30_03895	2.361e-10	63.0	COG2808@1|root,COG2808@2|Bacteria,1UYCC@1239|Firmicutes,4HBT7@91061|Bacilli,3IWP4@400634|Lysinibacillus	91061|Bacilli	O	protease	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
HKD3_k127_2501204_8	484770.UFO1_3189	1.173e-43	166.0	COG1392@1|root,COG1392@2|Bacteria,1V9BC@1239|Firmicutes,4H7YE@909932|Negativicutes	909932|Negativicutes	P	Phosphate transport regulator related to PhoU	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_2501204_2	768706.Desor_3059	4.66e-121	397.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia,260TM@186807|Peptococcaceae	186801|Clostridia	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD3_k127_2501204_9	1243664.CAVL020000019_gene3735	1.248e-43	165.0	2DUZZ@1|root,32UY8@2|Bacteria,1VGVG@1239|Firmicutes,4HR0H@91061|Bacilli,1ZR62@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1453
HKD3_k127_2501204_6	1536770.R50345_29910	6.477e-59	205.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli,26XT9@186822|Paenibacillaceae	91061|Bacilli	P	Alkylphosphonate utilization protein	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
HKD3_k127_2501204_7	1078085.HMPREF1210_01442	9.412e-52	184.0	COG2329@1|root,COG2329@2|Bacteria,1VAM1@1239|Firmicutes,4HJD7@91061|Bacilli,26HS5@186818|Planococcaceae	91061|Bacilli	S	enzyme involved in biosynthesis of extracellular polysaccharides	yqjZ	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD3_k127_2501204_0	1121091.AUMP01000016_gene1236	1.309e-266	828.0	COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli	91061|Bacilli	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
HKD3_k127_2501204_5	666686.B1NLA3E_08225	1.387e-75	260.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus	91061|Bacilli	EG	Spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
HKD3_k127_2522356_46	574375.BAGA_00730	1.722e-11	64.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,1ZCWU@1386|Bacillus	91061|Bacilli	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
HKD3_k127_2522356_10	1169144.KB910924_gene426	8.427e-197	617.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli,1ZBCJ@1386|Bacillus	91061|Bacilli	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_2522356_27	1405.DJ92_950	4.973e-118	385.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus	91061|Bacilli	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HKD3_k127_2522356_2	1405.DJ92_949	3.682e-275	860.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HKD3_k127_2522356_19	1169144.KB910924_gene423	3.84e-136	438.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,1ZB4W@1386|Bacillus	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HKD3_k127_2522356_26	574375.BAGA_00705	1.78e-118	382.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HKD3_k127_2522356_33	1405.DJ92_946	5.761e-94	312.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,1ZD4A@1386|Bacillus	91061|Bacilli	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
HKD3_k127_2522356_44	315749.Bcer98_2510	8.467e-27	110.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,1ZIVY@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD3_k127_2522356_37	574376.BAMA_08640	5.721e-63	217.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,1ZG6I@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yloU	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD3_k127_2522356_3	315749.Bcer98_2508	6.514e-258	805.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus	91061|Bacilli	S	kinase related to dihydroxyacetone kinase	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
HKD3_k127_2522356_30	545693.BMQ_4227	3.284e-104	342.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,1ZCRK@1386|Bacillus	91061|Bacilli	E	L-serine dehydratase	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
HKD3_k127_2522356_17	1444310.JANV01000086_gene180	1.727e-143	459.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,1ZC9A@1386|Bacillus	91061|Bacilli	E	L-serine dehydratase	sdaAA	GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
HKD3_k127_2522356_6	1460640.JCM19046_4285	2.131e-250	789.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus	91061|Bacilli	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HKD3_k127_2522356_35	574376.BAMA_08625	5.778e-80	270.0	COG1349@1|root,COG1349@2|Bacteria,1V3MJ@1239|Firmicutes,4HHFC@91061|Bacilli,1ZAV1@1386|Bacillus	91061|Bacilli	K	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism	fapR	-	-	-	-	-	-	-	-	-	-	-	4HBT,HTH_DeoR,MaoC_dehydratas
HKD3_k127_2522356_11	1169144.KB910924_gene415	2.996e-171	542.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,1ZBW8@1386|Bacillus	91061|Bacilli	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HKD3_k127_2522356_13	1169144.KB910924_gene414	1.636e-153	491.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HKD3_k127_2522356_24	1169144.KB910924_gene413	5.088e-121	392.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
HKD3_k127_2522356_43	1396.DJ87_1081	1.107e-32	127.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,1ZHY7@1386|Bacillus	91061|Bacilli	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD3_k127_2522356_20	1169144.KB910924_gene411	4.487e-135	433.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,1ZAPM@1386|Bacillus	91061|Bacilli	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HKD3_k127_2522356_0	574375.BAGA_00635	0.0	1492.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD3_k127_2522356_16	66692.ABC2296	1.752e-145	467.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,1ZB46@1386|Bacillus	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD3_k127_2522356_41	574376.BAMA_08585	1.229e-48	175.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,1ZH7Z@1386|Bacillus	91061|Bacilli	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
HKD3_k127_2522356_5	1169144.KB910924_gene407	1.388e-250	777.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,1ZB4I@1386|Bacillus	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD3_k127_2522356_42	315730.BcerKBAB4_3667	4.673e-46	166.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,1ZGXP@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD3_k127_2522356_36	315749.Bcer98_2494	4.804e-72	246.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,1ZFP2@1386|Bacillus	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HKD3_k127_2522356_25	545693.BMQ_4210	1.804e-120	391.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HKD3_k127_2522356_39	1347086.CCBA010000030_gene64	1.543e-61	215.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,1ZGDK@1386|Bacillus	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HKD3_k127_2522356_34	1169144.KB910924_gene401	1.313e-88	296.0	COG0681@1|root,COG0681@2|Bacteria,1TRAV@1239|Firmicutes,4HCTU@91061|Bacilli,1ZBW7@1386|Bacillus	91061|Bacilli	U	Belongs to the peptidase S26 family	sipS3	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD3_k127_2522356_14	315749.Bcer98_2490	5.93e-152	483.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,1ZB63@1386|Bacillus	91061|Bacilli	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	rbgA	GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HKD3_k127_2522356_29	315749.Bcer98_2489	2.267e-104	345.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD3_k127_2522356_8	649747.HMPREF0083_04343	3.754e-211	661.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,4HAR5@91061|Bacilli,26WD8@186822|Paenibacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_2522356_40	1408424.JHYI01000004_gene3401	2.857e-57	205.0	COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,4IQ6R@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
HKD3_k127_2522356_15	1234664.AMRO01000020_gene922	1.366e-145	469.0	COG3173@1|root,COG3173@2|Bacteria,1TSCJ@1239|Firmicutes,4HB2X@91061|Bacilli,1WES0@129337|Geobacillus	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
HKD3_k127_2522356_38	649747.HMPREF0083_04346	3.709e-62	222.0	COG2045@1|root,COG2045@2|Bacteria,1V56I@1239|Firmicutes,4HHF2@91061|Bacilli	91061|Bacilli	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
HKD3_k127_2522356_7	1120973.AQXL01000135_gene1374	1.207e-218	691.0	COG0318@1|root,COG0318@2|Bacteria,1TS8T@1239|Firmicutes,4HAP4@91061|Bacilli,27ANU@186823|Alicyclobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	fadD3	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_2522356_18	1120973.AQXL01000135_gene1375	2.912e-138	448.0	COG1735@1|root,COG1735@2|Bacteria,1TS8I@1239|Firmicutes,4HDZF@91061|Bacilli	91061|Bacilli	S	Phosphotriesterase family	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
HKD3_k127_2522356_45	1121091.AUMP01000002_gene2039	7.962e-12	67.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli	91061|Bacilli	IQ	Activates fatty acids by binding to coenzyme A	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD3_k127_2522356_23	265729.GS18_0203860	6.51e-129	417.0	COG1250@1|root,COG1250@2|Bacteria,1TPA4@1239|Firmicutes,4HEAF@91061|Bacilli,1ZC1S@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_2522356_28	1120973.AQXL01000134_gene1599	5.111e-110	361.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG_4	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
HKD3_k127_2522356_9	1444310.JANV01000086_gene157	1.257e-210	659.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
HKD3_k127_2522356_12	634956.Geoth_2713	1.787e-165	523.0	COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,4HA2J@91061|Bacilli,1WEXP@129337|Geobacillus	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU16100	CoA_binding,Ligase_CoA
HKD3_k127_2522356_31	1169144.KB910924_gene396	6.532e-104	346.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,1ZBZ3@1386|Bacillus	91061|Bacilli	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HKD3_k127_2522356_1	260799.BAS3684	0.0	1186.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
HKD3_k127_2522356_4	1405.DJ92_919	3.644e-254	786.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,1ZAR2@1386|Bacillus	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
HKD3_k127_2522356_22	1405.DJ92_918	1.281e-129	420.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,1ZB91@1386|Bacillus	91061|Bacilli	L	tyrosine recombinase XerC	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_2522356_32	574376.BAMA_08505	8.328e-97	319.0	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,1ZCMN@1386|Bacillus	91061|Bacilli	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
HKD3_k127_2522356_21	1396.DJ87_1102	1.811e-132	427.0	COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus	91061|Bacilli	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
HKD3_k127_25245_1	1169144.KB910928_gene1899	2.404e-166	528.0	COG0470@1|root,COG1067@1|root,COG0470@2|Bacteria,COG1067@2|Bacteria,1TP2K@1239|Firmicutes,4HB6F@91061|Bacilli,1ZBW1@1386|Bacillus	91061|Bacilli	LO	Belongs to the peptidase S16 family	lonB	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA,Lon_C
HKD3_k127_25245_0	1405.DJ92_1567	0.0	1276.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus	91061|Bacilli	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD3_k127_25245_2	1274524.BSONL12_09377	2.787e-26	109.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,1ZBX7@1386|Bacillus	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD3_k127_2526201_3	317025.Tcr_1013	1.434e-05	48.0	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,1RU3S@1236|Gammaproteobacteria,4637K@72273|Thiotrichales	72273|Thiotrichales	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
HKD3_k127_2526201_2	472759.Nhal_0267	1.958e-12	69.0	COG2337@1|root,COG2337@2|Bacteria,1MZJ8@1224|Proteobacteria,1S5J7@1236|Gammaproteobacteria,1WYXZ@135613|Chromatiales	135613|Chromatiales	T	Transcriptional modulator of MazE toxin, MazF	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HKD3_k127_2526201_1	1227360.C176_13747	1.353e-66	233.0	COG0346@1|root,COG0346@2|Bacteria,1V77S@1239|Firmicutes,4HJC0@91061|Bacilli,26FS7@186818|Planococcaceae	91061|Bacilli	E	Ring-cleavage extradiol dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD3_k127_2526201_0	1395513.P343_14335	6.511e-147	468.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,26PJV@186821|Sporolactobacillaceae	91061|Bacilli	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HKD3_k127_2531475_3	1246484.D479_10836	2.764e-20	97.0	COG1714@1|root,COG1714@2|Bacteria,1VC0R@1239|Firmicutes,4HMTR@91061|Bacilli,3NFGT@45667|Halobacillus	91061|Bacilli	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD3_k127_2531475_4	1298593.TOL_3330	1.092e-10	76.0	COG0699@1|root,COG0699@2|Bacteria,1R4IJ@1224|Proteobacteria,1RZ8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
HKD3_k127_2531475_1	574375.BAGA_11755	1.443e-43	161.0	2E61F@1|root,330QP@2|Bacteria,1VASH@1239|Firmicutes,4HKBT@91061|Bacilli,1ZI50@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4064)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4064
HKD3_k127_2531475_0	1385510.N781_09575	3.148e-119	395.0	COG3104@1|root,COG3104@2|Bacteria,1UHSN@1239|Firmicutes,4IS8A@91061|Bacilli	91061|Bacilli	E	Major Facilitator Superfamily	lmrP	-	-	ko:K08152	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1,Sugar_tr
HKD3_k127_258466_4	1117379.BABA_12116	1.023e-115	374.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZC6E@1386|Bacillus	91061|Bacilli	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_258466_7	1117379.BABA_23640	3.717e-09	58.0	29SGF@1|root,30DME@2|Bacteria,1UBF6@1239|Firmicutes,4IMTV@91061|Bacilli,1ZKU7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_258466_5	1243664.CAVL020000015_gene1911	9.622e-86	289.0	COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,1ZD4M@1386|Bacillus	91061|Bacilli	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	frnE	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	DSBA
HKD3_k127_258466_2	666686.B1NLA3E_20615	1.728e-230	721.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HE5I@91061|Bacilli,1ZBNN@1386|Bacillus	91061|Bacilli	EGP	Fungal trichothecene efflux pump (TRI12)	ypfE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD3_k127_258466_1	574375.BAGA_13510	1.182e-237	742.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,1ZB39@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes	dbpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD3_k127_258466_6	324057.Pjdr2_2691	6.578e-80	269.0	COG2353@1|root,COG2353@2|Bacteria,1V1NX@1239|Firmicutes,4HFXF@91061|Bacilli,26TZ9@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD3_k127_258466_0	1340434.AXVA01000010_gene5242	1.628e-276	862.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_258466_3	1449063.JMLS01000011_gene236	2.72e-217	683.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,26QMC@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_2593414_2	1487923.DP73_12790	2.607e-26	109.0	COG0500@1|root,COG2226@2|Bacteria,1V261@1239|Firmicutes,24D1W@186801|Clostridia,263RZ@186807|Peptococcaceae	186801|Clostridia	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
HKD3_k127_2593414_3	1118054.CAGW01000004_gene3723	8.354e-05	49.0	COG0316@1|root,COG0316@2|Bacteria,1VQ38@1239|Firmicutes,4HSDI@91061|Bacilli	91061|Bacilli	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
HKD3_k127_2593414_0	1034347.CAHJ01000058_gene716	2.807e-58	204.0	2F172@1|root,33U86@2|Bacteria,1VUP5@1239|Firmicutes,4HVPB@91061|Bacilli,1ZH8W@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2593414_1	1295642.H839_07454	9.854e-43	158.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1WF73@129337|Geobacillus	91061|Bacilli	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_2605790_0	1273538.G159_02490	8.488e-220	691.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HDYU@91061|Bacilli,26GUW@186818|Planococcaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_2605790_3	1192034.CAP_2778	1.285e-29	122.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,2YVX9@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HKD3_k127_2605790_2	1382356.JQMP01000003_gene1745	1.247e-125	413.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi,27YZ2@189775|Thermomicrobia	189775|Thermomicrobia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_2605790_4	573063.Metin_0435	7.466e-15	78.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,23QWX@183939|Methanococci	183939|Methanococci	V	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
HKD3_k127_2605790_1	1104324.P186_1129	9.083e-139	455.0	COG2031@1|root,arCOG04315@2157|Archaea,2XRZD@28889|Crenarchaeota	28889|Crenarchaeota	I	Short chain fatty acid transporter	-	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
HKD3_k127_2619931_1	1121091.AUMP01000002_gene2111	1.117e-105	348.0	COG2267@1|root,COG2267@2|Bacteria,1V1Y6@1239|Firmicutes,4HFW7@91061|Bacilli	91061|Bacilli	I	Alpha beta hydrolase	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HKD3_k127_2619931_3	1123252.ATZF01000013_gene2801	2.136e-37	145.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria	2|Bacteria	S	PFAM Iron-binding zinc finger CDGSH type	yjdI	-	1.6.3.4	ko:K07397,ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_19,zf-CDGSH
HKD3_k127_2619931_2	1395513.P343_11570	4.083e-42	156.0	COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli	91061|Bacilli	S	acetyltransferase'	yjdJ	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
HKD3_k127_2619931_0	1395513.P343_11560	1.072e-192	606.0	COG4292@1|root,COG4292@2|Bacteria,1TR19@1239|Firmicutes,4HCYV@91061|Bacilli	91061|Bacilli	S	Low temperature requirement protein A	ltrA	-	-	-	-	-	-	-	-	-	-	-	LtrA
HKD3_k127_2677747_4	1396.DJ87_3385	1.185e-11	64.0	2ESB9@1|root,30A2X@2|Bacteria,1U647@1239|Firmicutes,4IFTT@91061|Bacilli,1ZMZ0@1386|Bacillus	91061|Bacilli	S	histidinol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2677747_1	1169144.KB910949_gene3566	1.873e-193	614.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	ywdH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_2677747_0	1169144.KB910949_gene3563	0.0	1103.0	COG4412@1|root,COG4412@2|Bacteria,1U02W@1239|Firmicutes,4HJCX@91061|Bacilli,1ZC0P@1386|Bacillus	91061|Bacilli	V	Peptidase M6	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
HKD3_k127_2677747_2	198094.BA_1292	8.811e-44	162.0	COG1396@1|root,COG1396@2|Bacteria,1VAXE@1239|Firmicutes,4HKHB@91061|Bacilli,1ZHZH@1386|Bacillus	91061|Bacilli	K	transcriptional	sinR	GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0048519,GO:0050789,GO:0060255,GO:0065007	-	ko:K19449	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,SinI
HKD3_k127_2677747_3	1405.DJ92_3927	6.855e-29	123.0	COG1470@1|root,COG1470@2|Bacteria,1VMQY@1239|Firmicutes,4HSBN@91061|Bacilli	91061|Bacilli	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2681254_8	1405.DJ92_2660	7.454e-152	483.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,1ZBFC@1386|Bacillus	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
HKD3_k127_2681254_9	315749.Bcer98_0061	9.643e-140	447.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HKD3_k127_2681254_2	1405.DJ92_2658	0.0	1112.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZBEU@1386|Bacillus	91061|Bacilli	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD3_k127_2681254_13	315749.Bcer98_0059	1.071e-98	323.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,1ZB7B@1386|Bacillus	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
HKD3_k127_2681254_5	574376.BAMA_12160	2.733e-190	604.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,1ZBFQ@1386|Bacillus	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HKD3_k127_2681254_1	574375.BAGA_28630	0.0	1209.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus	91061|Bacilli	KT	stage II sporulation protein E	spoIIE	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
HKD3_k127_2681254_23	509191.AEDB02000028_gene2901	1.533e-14	76.0	2EFGV@1|root,3399G@2|Bacteria,1U5Y2@1239|Firmicutes,24WP5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2681254_15	315730.BcerKBAB4_0056	9.594e-66	228.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,1ZG7S@1386|Bacillus	91061|Bacilli	J	RNA binding protein (contains ribosomal protein S1 domain)	yabR	-	-	ko:K07571	-	-	-	-	ko00000	-	-	-	S1
HKD3_k127_2681254_21	1405.DJ92_2651	5.832e-26	110.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli	91061|Bacilli	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
HKD3_k127_2681254_16	1405.DJ92_2650	7.16e-63	222.0	2BYDV@1|root,32RAH@2|Bacteria,1V91M@1239|Firmicutes,4HIIQ@91061|Bacilli,1ZH7H@1386|Bacillus	91061|Bacilli	S	spore cortex biosynthesis protein	yabQ	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
HKD3_k127_2681254_19	796606.BMMGA3_00340	1.576e-45	167.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,4HPDE@91061|Bacilli,1ZGYU@1386|Bacillus	91061|Bacilli	S	Sporulation protein YabP	yabP	GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	YabP
HKD3_k127_2681254_20	1405.DJ92_2648	8.199e-37	141.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,1ZHXN@1386|Bacillus	91061|Bacilli	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	yabO	-	-	-	-	-	-	-	-	-	-	-	S4
HKD3_k127_2681254_4	1169144.KB910956_gene4116	1.272e-235	736.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus	91061|Bacilli	S	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
HKD3_k127_2681254_6	315730.BcerKBAB4_0050	1.014e-186	597.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	yabM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_2681254_14	1405.DJ92_2645	5.546e-95	312.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,4HDIW@91061|Bacilli,1ZAXU@1386|Bacillus	91061|Bacilli	K	stage V sporulation protein	spoVT	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
HKD3_k127_2681254_0	574376.BAMA_12100	0.0	1847.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus	91061|Bacilli	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HKD3_k127_2681254_22	1169144.KB910956_gene4120	6.548e-23	99.0	2EJ4H@1|root,33CVR@2|Bacteria,1VMIU@1239|Firmicutes,4HP24@91061|Bacilli,1ZJ5B@1386|Bacillus	91061|Bacilli	S	Peptide ABC transporter permease	yabK	-	-	-	-	-	-	-	-	-	-	-	DUF2757
HKD3_k127_2681254_12	315730.BcerKBAB4_0046	7.993e-99	325.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD3_k127_2681254_7	574376.BAMA_12085	1.157e-177	559.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,1ZD4C@1386|Bacillus	91061|Bacilli	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD3_k127_2681254_3	574376.BAMA_12080	3.056e-237	739.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
HKD3_k127_2681254_17	260799.BAS0047	4.119e-59	205.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,4HIPT@91061|Bacilli,1ZGXK@1386|Bacillus	91061|Bacilli	D	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation	spoVG	GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
HKD3_k127_2681254_18	574376.BAMA_12070	4.308e-58	205.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,1ZG9Q@1386|Bacillus	91061|Bacilli	J	translation initiation inhibitor, yjgF family	yabJ	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046360,GO:0046361,GO:0046394,GO:0046459,GO:0051790,GO:0071704,GO:0072330,GO:1901576	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HKD3_k127_2681254_11	1405.DJ92_2637	2.026e-135	435.0	COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,1ZAW9@1386|Bacillus	91061|Bacilli	F	pur operon repressor	purR	-	-	ko:K09685	-	-	-	-	ko00000,ko03000	-	-	-	Pribosyltran,PuR_N
HKD3_k127_2681254_10	574376.BAMA_12060	4.035e-139	445.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,1ZAYT@1386|Bacillus	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_2692038_5	545693.BMQ_2620	1.384e-42	160.0	COG3411@1|root,COG3411@2|Bacteria,1UI4T@1239|Firmicutes,4HK77@91061|Bacilli,1ZGMB@1386|Bacillus	91061|Bacilli	C	Cobalamin biosynthesis protein	cbiW	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
HKD3_k127_2692038_3	1501230.ET33_16345	9.713e-114	369.0	COG0778@1|root,COG0778@2|Bacteria,1UY9E@1239|Firmicutes,4HBU8@91061|Bacilli,26UCD@186822|Paenibacillaceae	91061|Bacilli	C	Cob(II)yrinic acid a,c-diamide reductase	bluB	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
HKD3_k127_2692038_4	1499968.TCA2_4017	1.297e-48	181.0	2DJRG@1|root,3072C@2|Bacteria,1U0WP@1239|Firmicutes,4IACT@91061|Bacilli,272NQ@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
HKD3_k127_2692038_1	665952.HMPREF1015_01448	2.016e-162	518.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,1ZAPU@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
HKD3_k127_2692038_0	1405.DJ92_5047	4.825e-191	604.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,1ZC00@1386|Bacillus	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU13130	Aldedh
HKD3_k127_2692038_6	315730.BcerKBAB4_1189	3.646e-20	93.0	29T7S@1|root,30EEJ@2|Bacteria,1UCGA@1239|Firmicutes,4INYP@91061|Bacilli,1ZP4R@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_2692038_2	1243664.CAVL020000049_gene5056	7.068e-122	395.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,1ZBR5@1386|Bacillus	91061|Bacilli	E	Belongs to the aspartokinase family	lysC	GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU03790	AA_kinase,ACT,ACT_7
HKD3_k127_2715148_3	574375.BAGA_13270	1.11e-18	87.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli,1ZS2F@1386|Bacillus	91061|Bacilli	E	O-acetylhomoserine	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_2715148_1	1405.DJ92_2494	8.152e-157	498.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,1ZCTU@1386|Bacillus	91061|Bacilli	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
HKD3_k127_2715148_0	1169144.KB910926_gene1156	2.086e-211	664.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZAVJ@1386|Bacillus	91061|Bacilli	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06610	ACT,Homoserine_dh,NAD_binding_3
HKD3_k127_2715148_2	796606.BMMGA3_14220	2.476e-41	153.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,1ZB11@1386|Bacillus	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32250	PALP
HKD3_k127_2716648_7	198094.BA_3911	3.544e-25	106.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,4HBJD@91061|Bacilli,1ZDBQ@1386|Bacillus	91061|Bacilli	E	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD3_k127_2716648_1	315749.Bcer98_2426	0.0	1023.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus	91061|Bacilli	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HKD3_k127_2716648_4	697284.ERIC2_c20840	4.263e-138	443.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli,26SQZ@186822|Paenibacillaceae	91061|Bacilli	C	ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
HKD3_k127_2716648_3	935836.JAEL01000001_gene658	3.367e-280	867.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus	91061|Bacilli	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD3_k127_2716648_6	315730.BcerKBAB4_3542	1.973e-59	208.0	COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli,1ZG72@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0342 family	ymcA	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	Com_YlbF
HKD3_k127_2716648_5	1169144.KB910924_gene285	6.172e-96	316.0	2BYGR@1|root,2ZIKA@2|Bacteria,1V30V@1239|Firmicutes,4HFX6@91061|Bacilli,1ZE20@1386|Bacillus	91061|Bacilli	S	Spore coat protein	cotE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06328	-	-	-	-	ko00000	-	-	-	CotE
HKD3_k127_2716648_0	471223.GWCH70_1202	0.0	1165.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1WF2E@129337|Geobacillus	91061|Bacilli	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HKD3_k127_2716648_2	260799.BAS3617	9.864e-295	914.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus	91061|Bacilli	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HKD3_k127_2739076_4	1274524.BSONL12_16854	5.852e-65	228.0	COG0583@1|root,COG0583@2|Bacteria,1UZ63@1239|Firmicutes,4HDFA@91061|Bacilli,1ZFCM@1386|Bacillus	91061|Bacilli	K	LysR substrate binding domain	ycgK	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
HKD3_k127_2739076_3	997296.PB1_12599	3.25e-99	332.0	COG0451@1|root,COG0451@2|Bacteria,1TQSN@1239|Firmicutes,4HBXX@91061|Bacilli,1ZAUJ@1386|Bacillus	91061|Bacilli	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
HKD3_k127_2739076_5	1173023.KE650771_gene3251	1.524e-35	144.0	COG3208@1|root,COG3208@2|Bacteria,1G16V@1117|Cyanobacteria,1JHZI@1189|Stigonemataceae	1117|Cyanobacteria	Q	Thioesterase domain	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Thioesterase
HKD3_k127_2739076_6	1408444.JHYC01000001_gene1096	7.533e-21	101.0	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,1SCGA@1236|Gammaproteobacteria,1JDBR@118969|Legionellales	118969|Legionellales	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
HKD3_k127_2739076_1	1174528.JH992893_gene5692	1.802e-187	602.0	COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1JKIU@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Abhydrolase_1,Acyl_transf_1,Hydrolase_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Sulfotransfer_3,ketoacyl-synt
HKD3_k127_2739076_0	643473.KB235930_gene3024	2.292e-274	875.0	COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HJCN@1161|Nostocales	1117|Cyanobacteria	IQ	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
HKD3_k127_2739076_2	268407.PWYN_21360	4.209e-158	517.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,26SUT@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_2743883_12	198094.BA_5571	2.832e-109	359.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,1ZBSE@1386|Bacillus	91061|Bacilli	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
HKD3_k127_2743883_6	315749.Bcer98_3850	4.077e-197	617.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,1ZCE9@1386|Bacillus	91061|Bacilli	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD3_k127_2743883_15	315730.BcerKBAB4_5128	4.778e-100	329.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,1ZBMX@1386|Bacillus	91061|Bacilli	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iYO844.BSU37060	TK
HKD3_k127_2743883_19	574376.BAMA_01475	1.074e-44	162.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,1ZHX3@1386|Bacillus	91061|Bacilli	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HKD3_k127_2743883_3	315749.Bcer98_3853	6.451e-246	763.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,1ZBN9@1386|Bacillus	91061|Bacilli	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD3_k127_2743883_9	574376.BAMA_01485	1.099e-182	574.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZC28@1386|Bacillus	91061|Bacilli	G	fructose-1,6-bisphosphatase	glpX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
HKD3_k127_2743883_4	1169144.KB910926_gene1219	4.237e-229	714.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZASB@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU37100	EPSP_synthase
HKD3_k127_2743883_13	1347369.CCAD010000090_gene1986	4.975e-107	349.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,1ZCA6@1386|Bacillus	91061|Bacilli	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU37110	TAL_FSA
HKD3_k127_2743883_10	315749.Bcer98_3856	1.462e-163	517.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,1ZBBA@1386|Bacillus	91061|Bacilli	G	Aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HKD3_k127_2743883_16	315730.BcerKBAB4_5134	8.116e-62	214.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,4HIXH@91061|Bacilli,1ZG9M@1386|Bacillus	91061|Bacilli	T	response regulator	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
HKD3_k127_2743883_17	1396.DJ87_3863	7.115e-61	214.0	COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF2529)	ywjG	-	-	-	-	-	-	-	-	-	-	-	DUF2529
HKD3_k127_2743883_2	315749.Bcer98_3859	6.058e-320	982.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,1ZB0S@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HKD3_k127_2743883_18	315749.Bcer98_3860	1.008e-44	168.0	COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,1ZH95@1386|Bacillus	91061|Bacilli	K	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling	rpoE	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	HARE-HTH
HKD3_k127_2743883_0	1382358.JHVN01000001_gene1170	0.0	1686.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,21WN2@150247|Anoxybacillus	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD3_k127_2743883_14	1405.DJ92_2434	3.121e-103	339.0	COG1309@1|root,COG1309@2|Bacteria,1UZQU@1239|Firmicutes,4HD4B@91061|Bacilli,1ZBMP@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	kstR2_2	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_2743883_5	574376.BAMA_01525	1.237e-221	689.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_2743883_8	1169144.KB910926_gene1211	2.497e-183	581.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	mmgC	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_2743883_11	315730.BcerKBAB4_5141	4.129e-151	481.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZAYV@1386|Bacillus	91061|Bacilli	I	Dehydrogenase	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_2743883_7	1169144.KB910926_gene1209	2.886e-192	606.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBYG@1386|Bacillus	91061|Bacilli	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	mmgA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
HKD3_k127_2743883_1	1169144.KB910926_gene1208	0.0	1011.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus	91061|Bacilli	C	COG0247 Fe-S oxidoreductase	ywjF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
HKD3_k127_281613_3	1169144.KB910972_gene2237	1.994e-30	130.0	COG3103@1|root,COG3807@1|root,COG4193@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,COG4193@2|Bacteria,1UI28@1239|Firmicutes,4ISBN@91061|Bacilli,1ZC2V@1386|Bacillus	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,PA14,SH3_3
HKD3_k127_281613_2	1169144.KB910963_gene2879	5.319e-40	152.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1ZH54@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HKD3_k127_281613_0	1169144.KB910963_gene2880	6.634e-272	841.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,1ZAT1@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HKD3_k127_281613_1	326423.RBAM_007090	1.159e-194	609.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,1ZB3K@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HKD3_k127_2817054_4	1243664.CAVL020000028_gene81	1.469e-25	107.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HFFH@91061|Bacilli	91061|Bacilli	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD3_k127_2817054_3	224308.BSU25810	2.313e-42	160.0	COG0640@1|root,COG0640@2|Bacteria,1V9XT@1239|Firmicutes,4HKP8@91061|Bacilli,1ZI0T@1386|Bacillus	91061|Bacilli	K	ArsR family transcriptional regulator	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
HKD3_k127_2817054_2	1294265.JCM21738_931	7.785e-48	178.0	COG0492@1|root,COG0492@2|Bacteria,1V9JY@1239|Firmicutes,4HIPN@91061|Bacilli	91061|Bacilli	O	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Pyr_redox_2
HKD3_k127_2817054_0	1131730.BAVI_02499	9.954e-150	481.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZB5H@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_2817054_1	1408254.T458_08925	1.299e-65	226.0	COG2249@1|root,COG2249@2|Bacteria,1VC9F@1239|Firmicutes,4HKPT@91061|Bacilli,275KS@186822|Paenibacillaceae	91061|Bacilli	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
HKD3_k127_2850900_3	1234664.AMRO01000035_gene2745	2.595e-140	452.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1WE1F@129337|Geobacillus	91061|Bacilli	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
HKD3_k127_2850900_8	1295642.H839_10148	3.662e-78	267.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,1WFFP@129337|Geobacillus	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU38290	TMP-TENI
HKD3_k127_2850900_4	471223.GWCH70_1938	1.026e-129	418.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,1WEYM@129337|Geobacillus	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HKD3_k127_2850900_7	1295642.H839_10158	7.389e-105	346.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,1WFQP@129337|Geobacillus	91061|Bacilli	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
HKD3_k127_2850900_0	1345697.M493_08445	2.057e-243	757.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HEUQ@91061|Bacilli,1WFZP@129337|Geobacillus	91061|Bacilli	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD3_k127_2850900_2	574375.BAGA_26880	2.175e-174	555.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,1ZBM0@1386|Bacillus	91061|Bacilli	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
HKD3_k127_2850900_6	471223.GWCH70_0389	1.031e-114	377.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,1WEMU@129337|Geobacillus	91061|Bacilli	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
HKD3_k127_2850900_1	1121091.AUMP01000018_gene955	6.039e-198	627.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli	91061|Bacilli	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
HKD3_k127_2850900_5	1131730.BAVI_11659	6.032e-119	387.0	COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus	91061|Bacilli	IQ	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate	yxjF	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HKD3_k127_2850900_9	1340434.AXVA01000035_gene113	1.203e-08	56.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus	91061|Bacilli	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD3_k127_2873435_1	315749.Bcer98_2676	4.705e-94	310.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,1ZB0K@1386|Bacillus	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD3_k127_2873435_2	279010.BL05385	8.574e-14	72.0	2DRT6@1|root,33CYC@2|Bacteria,1VMWG@1239|Firmicutes,4HR9A@91061|Bacilli,1ZK8Y@1386|Bacillus	91061|Bacilli	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
HKD3_k127_2873435_0	1234664.AMRO01000003_gene728	2.106e-233	737.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,1WEC4@129337|Geobacillus	91061|Bacilli	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	iSB619.SA_RS13395	FeoB_C,FeoB_N,Gate
HKD3_k127_2930116_1	315730.BcerKBAB4_0485	1.541e-73	250.0	COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli,1ZDYN@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_2930116_4	1295642.H839_02106	4.538e-38	144.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1WGR9@129337|Geobacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_2930116_3	1405.DJ92_3377	2.386e-47	172.0	COG0607@1|root,COG0607@2|Bacteria,1VACI@1239|Firmicutes,4HKIQ@91061|Bacilli,1ZRCQ@1386|Bacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_2930116_0	1461580.CCAS010000051_gene3618	1.402e-110	364.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HFDT@91061|Bacilli,1ZQ2C@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	cysL	-	-	ko:K21900	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HKD3_k127_2930116_2	1405.DJ92_2230	4.522e-64	225.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,1ZATM@1386|Bacillus	91061|Bacilli	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
HKD3_k127_2939404_4	1121286.AUMT01000023_gene1732	1.177e-84	289.0	COG1028@1|root,COG1028@2|Bacteria,4PPJR@976|Bacteroidetes,1I7YX@117743|Flavobacteriia,3ZQ4Y@59732|Chryseobacterium	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_2939404_5	545693.BMQ_3852	5.686e-47	172.0	COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,1ZFTI@1386|Bacillus	91061|Bacilli	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD3_k127_2939404_1	997296.PB1_10954	1.421e-188	594.0	COG2141@1|root,COG2141@2|Bacteria,1TW8W@1239|Firmicutes,4HBIF@91061|Bacilli,1ZR3K@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.35	ko:K17228	ko00920,map00920	-	R10203	RC02556,RC03080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HKD3_k127_2939404_2	1169144.KB910975_gene2391	1.458e-174	557.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ywqF	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD3_k127_2939404_0	315749.Bcer98_3744	1.651e-212	663.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iSB619.SA_RS11005	Epimerase_2
HKD3_k127_2939404_3	35841.BT1A1_3273	9.23e-158	522.0	COG4193@1|root,COG4733@1|root,COG4193@2|Bacteria,COG4733@2|Bacteria,1UI28@1239|Firmicutes,4ISBN@91061|Bacilli,1ZC2V@1386|Bacillus	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.2.1.96,3.5.1.28	ko:K01227,ko:K13714	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH73	-	ChW,Glucosaminidase,PA14,SH3_3,SH3_8
HKD3_k127_2955891_3	1051501.AYTL01000027_gene1052	1.942e-65	224.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	pdhD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD3_k127_2955891_1	1297581.H919_05946	1.18e-198	626.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,21WTD@150247|Anoxybacillus	91061|Bacilli	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_2955891_2	315749.Bcer98_2673	4.212e-188	589.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,1ZBJ1@1386|Bacillus	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05355,iYO844.BSU14590	Transket_pyr,Transketolase_C
HKD3_k127_2955891_0	1405.DJ92_1067	5.506e-215	671.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,1ZBE0@1386|Bacillus	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD3_k127_303537_16	1340434.AXVA01000008_gene3653	6.36e-12	66.0	COG1177@1|root,COG1177@2|Bacteria,1V0UU@1239|Firmicutes,4HD56@91061|Bacilli,1ZF0W@1386|Bacillus	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
HKD3_k127_303537_2	1340434.AXVA01000008_gene3654	1.528e-141	456.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,1ZC8R@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
HKD3_k127_303537_4	1340434.AXVA01000008_gene3655	5.107e-115	376.0	COG1349@1|root,COG1349@2|Bacteria,1TSHY@1239|Firmicutes,4HD6Y@91061|Bacilli,1ZCCE@1386|Bacillus	91061|Bacilli	K	COG1349 Transcriptional regulators of sugar metabolism	yulB	-	-	ko:K02530,ko:K06608	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HKD3_k127_303537_11	406124.ACPC01000009_gene1377	1.779e-35	135.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHUB@1386|Bacillus	91061|Bacilli	K	'Cold-shock' DNA-binding domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD3_k127_303537_3	634956.Geoth_1639	2.946e-125	414.0	COG3420@1|root,COG3420@2|Bacteria,1UN63@1239|Firmicutes,4HAZN@91061|Bacilli,1WFE8@129337|Geobacillus	91061|Bacilli	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
HKD3_k127_303537_10	634956.Geoth_1640	2.674e-62	222.0	COG4314@1|root,COG4314@2|Bacteria,1V86E@1239|Firmicutes,4HJXZ@91061|Bacilli,1WGI5@129337|Geobacillus	91061|Bacilli	C	NosL	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD3_k127_303537_6	1169144.KB910933_gene4198	1.154e-97	326.0	COG1277@1|root,COG1277@2|Bacteria,1UZYB@1239|Firmicutes,4HEYC@91061|Bacilli,1ZDVJ@1386|Bacillus	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
HKD3_k127_303537_9	634956.Geoth_1642	3.416e-74	256.0	COG1131@1|root,COG1131@2|Bacteria,1UZ5J@1239|Firmicutes,4HJEF@91061|Bacilli,1WFV2@129337|Geobacillus	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Rad17
HKD3_k127_303537_7	1196323.ALKF01000186_gene5738	1.957e-97	326.0	COG1506@1|root,COG1506@2|Bacteria,1U5SB@1239|Firmicutes,4HB1A@91061|Bacilli,26VKY@186822|Paenibacillaceae	91061|Bacilli	E	Dienelactone hydrolase family	ytmA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HKD3_k127_303537_5	1169144.KB910961_gene4069	1.094e-103	343.0	COG0726@1|root,COG0726@2|Bacteria,1V5E9@1239|Firmicutes,4HNGI@91061|Bacilli,1ZM7D@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_303537_8	574375.BAGA_04330	1.629e-79	269.0	COG1418@1|root,COG1418@2|Bacteria,1V3UK@1239|Firmicutes,4HH7I@91061|Bacilli,1ZFMK@1386|Bacillus	91061|Bacilli	S	phosphohydrolase	yueE	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
HKD3_k127_303537_15	333138.LQ50_08140	4.049e-15	78.0	28P1F@1|root,2ZBXS@2|Bacteria,1V1PR@1239|Firmicutes,4IAIX@91061|Bacilli,1ZIVA@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2680)	yckD	-	-	-	-	-	-	-	-	-	-	-	DUF2680
HKD3_k127_303537_14	1121091.AUMP01000037_gene2949	2.062e-27	113.0	2BA67@1|root,3449N@2|Bacteria,1W09C@1239|Firmicutes,4HY99@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3055)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3055
HKD3_k127_303537_1	1396.DJ87_1767	1.819e-164	526.0	COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes,4HB8E@91061|Bacilli,1ZC21@1386|Bacillus	91061|Bacilli	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
HKD3_k127_303537_13	1157490.EL26_10560	3.04e-31	126.0	COG3296@1|root,COG3296@2|Bacteria,1VJNI@1239|Firmicutes,4HPKT@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
HKD3_k127_303537_0	1169144.KB910952_gene3192	1.942e-179	569.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,1ZBEY@1386|Bacillus	91061|Bacilli	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HKD3_k127_303537_12	1131730.BAVI_05964	7.232e-32	125.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,1ZBP3@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD3_k127_3117853_1	574375.BAGA_03160	8.966e-28	114.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,1ZI3X@1386|Bacillus	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HKD3_k127_3117853_0	260799.BAS4222	1.95e-143	462.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD3_k127_3117853_2	796606.BMMGA3_12080	7.307e-16	77.0	2EJUP@1|root,33DJB@2|Bacteria,1VMIR@1239|Firmicutes,4HRA6@91061|Bacilli,1ZK02@1386|Bacillus	91061|Bacilli	S	YqzM-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YqzM
HKD3_k127_3117853_3	574375.BAGA_03175	6.792e-06	48.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HKD3_k127_3126548_2	1380408.AVGH01000005_gene2653	2.481e-93	312.0	COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,4HGNR@91061|Bacilli,21WJR@150247|Anoxybacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_10,Acetyltransf_9,GNAT_acetyltran
HKD3_k127_3126548_1	1169144.KB910937_gene1054	3.872e-149	478.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HE1N@91061|Bacilli,1ZQ3Q@1386|Bacillus	91061|Bacilli	O	SPFH domain / Band 7 family	hflK	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD3_k127_3126548_4	315730.BcerKBAB4_1923	1.515e-40	155.0	COG1585@1|root,COG1585@2|Bacteria,1VCUJ@1239|Firmicutes,4HPB4@91061|Bacilli	91061|Bacilli	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
HKD3_k127_3126548_3	574376.BAMA_19760	4.489e-71	249.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	vanYB	-	3.4.16.4,3.4.17.14	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
HKD3_k127_3126548_0	198094.BA_2068	1.883e-162	519.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus	91061|Bacilli	M	stage II sporulation protein P	-	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
HKD3_k127_3126548_5	1382358.JHVN01000002_gene2343	1.621e-17	84.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,21V5I@150247|Anoxybacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_3135861_12	649747.HMPREF0083_05281	3.119e-16	78.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
HKD3_k127_3135861_6	649747.HMPREF0083_00829	1.047e-90	313.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,26SPP@186822|Paenibacillaceae	91061|Bacilli	K	RNA polymerase	sigL	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD3_k127_3135861_2	1396.DJ87_5764	1.564e-166	526.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli,1ZB36@1386|Bacillus	91061|Bacilli	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
HKD3_k127_3135861_5	574375.BAGA_25000	7.035e-100	328.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,1ZD5C@1386|Bacillus	91061|Bacilli	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
HKD3_k127_3135861_1	1169144.KB910989_gene2770	1.537e-231	722.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1ZCBQ@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD3_k127_3135861_13	1347369.CCAD010000066_gene3619	4.57e-12	68.0	29S5T@1|root,30DAB@2|Bacteria,1UB2G@1239|Firmicutes,4IMF9@91061|Bacilli,1ZK0W@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3135861_9	1169144.KB910989_gene2769	2.161e-37	143.0	2C9CP@1|root,30A7R@2|Bacteria,1U6AX@1239|Firmicutes,4IG2D@91061|Bacilli,1ZN1T@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF3797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3797,Sigma70_r4
HKD3_k127_3135861_3	1169144.KB910989_gene2768	7.734e-125	402.0	COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,1ZBFB@1386|Bacillus	91061|Bacilli	F	Deoxycytidine kinase	dck	-	2.7.1.74,2.7.1.76	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	-	R00185,R01666,R02089	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
HKD3_k127_3135861_7	1396.DJ87_5756	7.045e-76	258.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,1ZFRP@1386|Bacillus	91061|Bacilli	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
HKD3_k127_3135861_0	1169144.KB910989_gene2764	4.857e-264	822.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus	91061|Bacilli	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD3_k127_3135861_8	1169144.KB910989_gene2763	9.109e-49	176.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,1ZGZI@1386|Bacillus	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
HKD3_k127_3135861_4	315749.Bcer98_0020	2.739e-119	384.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,1ZBDK@1386|Bacillus	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HKD3_k127_3135861_11	1169144.KB910989_gene2761	1.282e-20	93.0	2EHEM@1|root,33B6J@2|Bacteria,1VM3Z@1239|Firmicutes,4HR3I@91061|Bacilli,1ZIUR@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2508)	yaaL	-	-	-	-	-	-	-	-	-	-	-	DUF2508
HKD3_k127_3135861_10	1169144.KB910989_gene2760	3.764e-22	99.0	2DRM3@1|root,33C8V@2|Bacteria,1VKUE@1239|Firmicutes,4HRJC@91061|Bacilli,1ZRYA@1386|Bacillus	91061|Bacilli	S	SigmaK-factor processing regulatory protein BofA	bofA	-	-	ko:K06317	-	-	-	-	ko00000	-	-	-	BofA
HKD3_k127_3384773_6	324057.Pjdr2_2781	2.66e-11	69.0	COG1309@1|root,COG1309@2|Bacteria,1VJ8P@1239|Firmicutes,4HQG7@91061|Bacilli,270VT@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_3384773_0	1169144.KB910972_gene2241	2.398e-211	662.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus	91061|Bacilli	S	COG2270 Permeases of the major facilitator superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD3_k127_3384773_1	1169144.KB910972_gene2240	3.495e-206	650.0	COG1524@1|root,COG1524@2|Bacteria,1TRZ7@1239|Firmicutes,4HAY5@91061|Bacilli,1ZD4Z@1386|Bacillus	91061|Bacilli	S	type I phosphodiesterase nucleotide pyrophosphatase	npp	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD3_k127_3384773_3	1405.DJ92_3043	1.079e-31	126.0	COG4840@1|root,COG4840@2|Bacteria,1VEYR@1239|Firmicutes,4HNKK@91061|Bacilli,1ZJ0U@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0435 family	yfkK	-	-	-	-	-	-	-	-	-	-	-	DUF1128
HKD3_k127_3384773_2	1169144.KB910940_gene2509	4.359e-73	248.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,1ZG7W@1386|Bacillus	91061|Bacilli	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD3_k127_3384773_4	1169144.KB910940_gene2511	5.12e-16	79.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD3_k127_362143_0	997296.PB1_03860	0.0	1015.0	COG3733@1|root,COG3733@2|Bacteria,1TY2K@1239|Firmicutes,4I75Q@91061|Bacilli,1ZC7C@1386|Bacillus	91061|Bacilli	Q	Copper amine oxidase, enzyme domain	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
HKD3_k127_362143_15	666686.B1NLA3E_18965	3.644e-27	117.0	2ES56@1|root,33JPZ@2|Bacteria,1U2H0@1239|Firmicutes,4IM8G@91061|Bacilli,1ZJGI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_362143_1	666686.B1NLA3E_18960	2.465e-210	661.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus	91061|Bacilli	P	Ammonium transporter	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iYO844.BSU36510	Ammonium_transp
HKD3_k127_362143_3	1395513.P343_10805	5.04e-165	522.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HC7T@91061|Bacilli	91061|Bacilli	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD3_k127_362143_5	1169144.KB910925_gene152	2.48e-155	494.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,1ZBUC@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	ypjC	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_362143_14	1169144.KB910925_gene151	5.041e-54	191.0	COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,4HISK@91061|Bacilli,1ZH1U@1386|Bacillus	91061|Bacilli	S	Nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
HKD3_k127_362143_8	574376.BAMA_14135	1.025e-134	434.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,1ZAWD@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22490	DapB_C,DapB_N
HKD3_k127_362143_12	574375.BAGA_16590	1.79e-66	228.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,4HH64@91061|Bacilli,1ZGAF@1386|Bacillus	91061|Bacilli	G	methylglyoxal synthase	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HKD3_k127_362143_10	315749.Bcer98_1258	2.167e-116	377.0	COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus	91061|Bacilli	S	proteins, LmbE homologs	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
HKD3_k127_362143_2	1405.DJ92_4186	7.43e-182	575.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus	91061|Bacilli	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_362143_11	491915.Aflv_1124	9.298e-112	373.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,21W3D@150247|Anoxybacillus	91061|Bacilli	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HKD3_k127_362143_4	1396.DJ87_5425	2.136e-163	518.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HKD3_k127_362143_7	260799.BAS1449	3.862e-139	449.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus	91061|Bacilli	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22430	Pantoate_transf
HKD3_k127_362143_9	574375.BAGA_16560	1.673e-123	402.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,1ZAV5@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HKD3_k127_362143_13	1169144.KB910925_gene142	1.648e-62	216.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,1ZG9V@1386|Bacillus	91061|Bacilli	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HKD3_k127_362143_6	1396.DJ87_5420	2.944e-153	492.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
HKD3_k127_363670_1	1405.DJ92_2511	7.176e-130	427.0	COG0438@1|root,COG0438@2|Bacteria,1V4R8@1239|Firmicutes,4HHG5@91061|Bacilli,1ZEX9@1386|Bacillus	91061|Bacilli	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	O-antigen_lig
HKD3_k127_363670_0	574376.BAMA_01865	2.732e-161	514.0	COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,4HB04@91061|Bacilli,1ZBZK@1386|Bacillus	91061|Bacilli	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_363670_2	1169144.KB910926_gene1145	7.805e-100	331.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,4HH6B@91061|Bacilli,1ZFMX@1386|Bacillus	91061|Bacilli	M	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
HKD3_k127_3643550_2	1305836.AXVE01000001_gene2726	3.942e-80	268.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,26EAW@186818|Planococcaceae	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
HKD3_k127_3643550_0	1384057.CD33_11710	2.134e-270	846.0	2C593@1|root,2Z84R@2|Bacteria,1U546@1239|Firmicutes,4HEHB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3643550_1	1185653.A1A1_09911	4.033e-204	641.0	COG0026@1|root,COG0026@2|Bacteria,1TTDR@1239|Firmicutes,4HDHY@91061|Bacilli	91061|Bacilli	F	Carboxylate--amine ligase	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
HKD3_k127_3643550_3	1384057.CD33_11695	6.613e-18	84.0	COG0454@1|root,COG0456@2|Bacteria,1TSZY@1239|Firmicutes,4HAYD@91061|Bacilli	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yjbC	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
HKD3_k127_3644323_11	574376.BAMA_18080	4.241e-21	94.0	2D1ET@1|root,32TAJ@2|Bacteria,1V8Q4@1239|Firmicutes,4HQUW@91061|Bacilli,1ZI5D@1386|Bacillus	91061|Bacilli	S	Cell division protein FtsJ	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3644323_10	1396.DJ87_3366	8.952e-23	98.0	2BX75@1|root,32YR8@2|Bacteria,1VJMT@1239|Firmicutes,4HP70@91061|Bacilli,1ZIU2@1386|Bacillus	91061|Bacilli	S	small acid-soluble spore protein	sspD	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
HKD3_k127_3644323_5	315730.BcerKBAB4_1227	6.466e-65	228.0	COG2030@1|root,COG2030@2|Bacteria,1V6MY@1239|Firmicutes,4HJ4K@91061|Bacilli,1ZHNF@1386|Bacillus	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HKD3_k127_3644323_8	1396.DJ87_3364	7.997e-52	188.0	2D5FM@1|root,32TJ0@2|Bacteria,1VC6G@1239|Firmicutes,4HKFH@91061|Bacilli,1ZHDG@1386|Bacillus	91061|Bacilli	S	polyhydroxyalkanoic acid inclusion protein PhaP	phaP	-	-	-	-	-	-	-	-	-	-	-	PhaP_Bmeg
HKD3_k127_3644323_6	315749.Bcer98_1041	2.007e-60	211.0	COG1695@1|root,COG1695@2|Bacteria,1V7D3@1239|Firmicutes,4HINI@91061|Bacilli,1ZGV9@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	phaQ	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD3_k127_3644323_7	315749.Bcer98_1042	3.95e-60	211.0	2DSEU@1|root,33FV9@2|Bacteria,1VCU2@1239|Firmicutes,4HPZM@91061|Bacilli,1ZGVC@1386|Bacillus	91061|Bacilli	S	polyhydroxyalkanoic acid synthase, PhaR subunit	phaR	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
HKD3_k127_3644323_2	198094.BA_1330	5.858e-121	392.0	COG1028@1|root,COG1028@2|Bacteria,1UZB2@1239|Firmicutes,4HA42@91061|Bacilli,1ZDHI@1386|Bacillus	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
HKD3_k127_3644323_1	1169144.KB910951_gene3324	1.44e-202	633.0	COG3243@1|root,COG3243@2|Bacteria,1V0SA@1239|Firmicutes,4HCRB@91061|Bacilli,1ZAX8@1386|Bacillus	91061|Bacilli	I	Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD3_k127_3644323_9	198094.BA_1334	1.607e-48	177.0	2B33U@1|root,31VRG@2|Bacteria,1V7D5@1239|Firmicutes,4HIPZ@91061|Bacilli,1ZGYF@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3905
HKD3_k127_3644323_14	1169144.KB910951_gene3321	7.736e-08	54.0	2EHTK@1|root,33BJ8@2|Bacteria,1VN5I@1239|Firmicutes,4HRCP@91061|Bacilli,1ZJY3@1386|Bacillus	91061|Bacilli	S	Stage 0 Sporulation Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3644323_0	1169144.KB910951_gene3320	1.659e-304	940.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,4HA0Y@91061|Bacilli,1ZAU7@1386|Bacillus	91061|Bacilli	C	Fe-S oxidoreductase	bchE	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
HKD3_k127_3644323_4	315730.BcerKBAB4_1246	5.238e-86	289.0	COG0235@1|root,COG0235@2|Bacteria,1TT62@1239|Firmicutes,4HHI6@91061|Bacilli,1ZCA2@1386|Bacillus	91061|Bacilli	E	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	3.1.3.87,4.2.1.109	ko:K08964,ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07392,R07394	RC01939,RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
HKD3_k127_3644323_3	1405.DJ92_3974	2.761e-105	347.0	COG2861@1|root,COG2861@2|Bacteria,1V413@1239|Firmicutes,4HCXZ@91061|Bacilli,1ZEQY@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
HKD3_k127_3644323_13	1169144.KB910951_gene3316	9.902e-12	69.0	29T0H@1|root,30E6Y@2|Bacteria,1UC6Y@1239|Firmicutes,4INPE@91061|Bacilli,1ZNRF@1386|Bacillus	91061|Bacilli	S	Spo0E like sporulation regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoOE-like
HKD3_k127_3644323_12	315749.Bcer98_1059	3.724e-20	91.0	COG4191@1|root,COG4191@2|Bacteria,1VS6S@1239|Firmicutes,4HV7J@91061|Bacilli,1ZS26@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K13532	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3149,HATPase_c,HisKA,dCache_1
HKD3_k127_3657366_8	315749.Bcer98_1618	3.804e-25	105.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZGM0@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0403 family	yphP	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HKD3_k127_3657366_1	1405.DJ92_4742	6.392e-162	517.0	COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli,1ZB7F@1386|Bacillus	91061|Bacilli	C	COG0694 Thioredoxin-like proteins and domains	ypgR	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact
HKD3_k127_3657366_7	1396.DJ87_2624	1.019e-45	168.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_3657366_4	574375.BAGA_29250	7.508e-100	329.0	COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,1ZDDI@1386|Bacillus	91061|Bacilli	S	Nitroreductase family	XK27_02070	-	-	ko:K07078	-	-	-	-	ko00000	-	-	-	Nitroreductase
HKD3_k127_3657366_3	1227352.C173_17891	2.061e-104	345.0	COG1119@1|root,COG1119@2|Bacteria,1TRR4@1239|Firmicutes,4HB4U@91061|Bacilli,26QE5@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter, ATP-binding protein	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HKD3_k127_3657366_5	574375.BAGA_18405	2.301e-94	315.0	COG4760@1|root,COG4760@2|Bacteria,1TQ9Z@1239|Firmicutes,4HEPV@91061|Bacilli,1ZGPC@1386|Bacillus	91061|Bacilli	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
HKD3_k127_3657366_0	574376.BAMA_05690	1.892e-306	949.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,1ZBTF@1386|Bacillus	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_3657366_6	198094.BA_2163	1.41e-92	308.0	COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,1ZB0E@1386|Bacillus	91061|Bacilli	S	phosphohydrolase	ypgQ	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
HKD3_k127_3657366_9	1169144.KB910937_gene1020	6.653e-24	108.0	2CCDB@1|root,33G1C@2|Bacteria,1VMB0@1239|Firmicutes,4HZC5@91061|Bacilli,1ZIVV@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3657366_2	1111479.AXAR01000001_gene40	1.645e-114	373.0	COG4705@1|root,COG4705@2|Bacteria,1U1EC@1239|Firmicutes,4HCNA@91061|Bacilli	91061|Bacilli	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
HKD3_k127_3676331_1	315749.Bcer98_0234	1.07e-96	318.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
HKD3_k127_3676331_0	260799.BAS0232	2.667e-201	635.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_368824_3	1405.DJ92_1549	3.825e-39	147.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,1ZC8X@1386|Bacillus	91061|Bacilli	M	Involved in formation and maintenance of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HKD3_k127_368824_0	574376.BAMA_11120	8.434e-199	622.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZB43@1386|Bacillus	91061|Bacilli	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD3_k127_368824_1	574376.BAMA_11125	4.133e-120	388.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,1ZBYH@1386|Bacillus	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD3_k127_368824_2	574376.BAMA_11130	3.521e-72	247.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,1ZGDP@1386|Bacillus	91061|Bacilli	D	septum formation protein Maf	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HKD3_k127_368824_4	1169144.KB910928_gene1885	6.161e-20	97.0	2EH4E@1|root,33AWD@2|Bacteria,1VKBC@1239|Firmicutes,4HREV@91061|Bacilli,1ZJDB@1386|Bacillus	91061|Bacilli	-	-	-	-	-	ko:K06380	-	-	-	-	ko00000	-	-	-	SPOR
HKD3_k127_3694513_6	198094.BA_4983	1.036e-15	78.0	COG2021@1|root,COG2021@2|Bacteria,1TQSV@1239|Firmicutes,4HBNC@91061|Bacilli,1ZEVF@1386|Bacillus	91061|Bacilli	E	Belongs to the AB hydrolase superfamily. MetX family	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD3_k127_3694513_2	1405.DJ92_4577	4.178e-147	472.0	COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	ywcH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_3694513_3	260799.BAS5267	9.162e-85	293.0	COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli,1ZS2E@1386|Bacillus	91061|Bacilli	T	5TMR of 5TMR-LYT	yhcK1	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GGDEF
HKD3_k127_3694513_5	1169144.KB910926_gene1149	1.037e-17	85.0	COG2879@1|root,COG2879@2|Bacteria,1VJGC@1239|Firmicutes,4HP41@91061|Bacilli,1ZJFV@1386|Bacillus	91061|Bacilli	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
HKD3_k127_3694513_0	1405.DJ92_2506	0.0	1145.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus	91061|Bacilli	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
HKD3_k127_3694513_4	1169144.KB910926_gene1147	2.42e-73	254.0	COG3279@1|root,COG3279@2|Bacteria,1UBGZ@1239|Firmicutes,4IMW6@91061|Bacilli,1ZKZU@1386|Bacillus	91061|Bacilli	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD3_k127_3694513_1	574375.BAGA_13320	1.12e-192	608.0	COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,4IS86@91061|Bacilli,1ZBK2@1386|Bacillus	91061|Bacilli	G	Major Facilitator	yceI	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
HKD3_k127_36967_0	574376.BAMA_22365	1.335e-243	762.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,1ZBGC@1386|Bacillus	91061|Bacilli	E	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine	yitJ	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
HKD3_k127_36967_1	796606.BMMGA3_08600	9.222e-186	586.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	metB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_36967_2	574376.BAMA_22355	6.86e-184	582.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	metC	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU11880	Cys_Met_Meta_PP
HKD3_k127_36967_4	574376.BAMA_22340	2.596e-42	158.0	COG0640@1|root,COG0640@2|Bacteria,1VF14@1239|Firmicutes,4HP8Z@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD3_k127_36967_3	1169144.KB910968_gene3352	1.799e-140	455.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,4HE1P@91061|Bacilli,1ZR9F@1386|Bacillus	91061|Bacilli	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
HKD3_k127_36967_5	1169144.KB910968_gene3353	4.462e-20	90.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqgX	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HKD3_k127_370334_11	1405.DJ92_3728	2.02e-58	204.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,1ZBIZ@1386|Bacillus	91061|Bacilli	H	Lipoate-protein ligase	lplJ	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
HKD3_k127_370334_4	1123290.AUDQ01000001_gene2810	4.166e-193	614.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26DFP@186818|Planococcaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	lcfB_2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD3_k127_370334_5	315730.BcerKBAB4_1027	2.005e-179	570.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus	91061|Bacilli	O	Peptidase M48	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
HKD3_k127_370334_2	1169144.KB910927_gene1384	1.536e-260	811.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,1ZBY7@1386|Bacillus	91061|Bacilli	C	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
HKD3_k127_370334_3	574375.BAGA_21570	6.195e-254	785.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli,1ZBPW@1386|Bacillus	91061|Bacilli	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
HKD3_k127_370334_12	265729.GS18_0213130	1.646e-31	126.0	29S4J@1|root,30D92@2|Bacteria,1UB0M@1239|Firmicutes,4IMDG@91061|Bacilli,1ZJW0@1386|Bacillus	91061|Bacilli	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
HKD3_k127_370334_10	1169144.KB910927_gene1382	1.817e-61	217.0	COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,1ZGB4@1386|Bacillus	91061|Bacilli	K	Competence transcription factor	comK	-	-	ko:K02250	ko02024,map02024	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	ComK
HKD3_k127_370334_8	574375.BAGA_21550	1.8e-73	251.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZAPC@1386|Bacillus	91061|Bacilli	U	Belongs to the peptidase S26 family	spsB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD3_k127_370334_1	1169144.KB910927_gene1376	0.0	1561.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus	91061|Bacilli	L	ATP-dependent helicase deoxyribonuclease subunit B	rexB	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
HKD3_k127_370334_0	1169144.KB910927_gene1375	0.0	1606.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	addA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HKD3_k127_370334_17	1405.DJ92_3759	5.579e-16	79.0	2C5QJ@1|root,33C5U@2|Bacteria,1VK5Y@1239|Firmicutes,4HR2R@91061|Bacilli,1ZIUX@1386|Bacillus	91061|Bacilli	S	Spore germination protein	gerPD	-	-	ko:K06302	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_370334_7	574376.BAMA_17195	1.485e-86	290.0	2EBJR@1|root,32VKI@2|Bacteria,1VBM1@1239|Firmicutes,4HN23@91061|Bacilli,1ZQRS@1386|Bacillus	91061|Bacilli	S	Spore germination protein GerPC	gerPC	-	-	ko:K06301	-	-	-	-	ko00000	-	-	-	GerPC
HKD3_k127_370334_15	574376.BAMA_17200	5.336e-23	100.0	2EBHF@1|root,335HY@2|Bacteria,1VHMW@1239|Firmicutes,4HPZZ@91061|Bacilli,1ZIW2@1386|Bacillus	91061|Bacilli	S	cell differentiation	gerPB	-	-	ko:K06300	-	-	-	-	ko00000	-	-	-	GerPB
HKD3_k127_370334_6	1267533.KB906736_gene1013	7.433e-119	400.0	COG2936@1|root,COG2936@2|Bacteria,3Y33N@57723|Acidobacteria	57723|Acidobacteria	S	Hydrolase CocE NonD family	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
HKD3_k127_370334_9	1173024.KI912148_gene3847	1.677e-65	235.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,1JKIF@1189|Stigonemataceae	1117|Cyanobacteria	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
HKD3_k127_370334_16	862908.BMS_1422	1.061e-21	98.0	COG0824@1|root,COG0824@2|Bacteria,1REIH@1224|Proteobacteria,42UZ3@68525|delta/epsilon subdivisions,2MT36@213481|Bdellovibrionales,2WSFV@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
HKD3_k127_3716884_2	1396.DJ87_3941	4.19e-94	318.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,1ZBT5@1386|Bacillus	91061|Bacilli	K	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)	tagU	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD3_k127_3716884_1	1444310.JANV01000177_gene1771	2.025e-144	468.0	COG0665@1|root,COG0665@2|Bacteria,1TRYK@1239|Firmicutes,4HAM4@91061|Bacilli,1ZC7R@1386|Bacillus	91061|Bacilli	E	FAD dependent oxidoreductase	solA	-	1.5.3.1	ko:K00301,ko:K02846	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
HKD3_k127_3716884_0	198094.BA_0493	1.308e-234	730.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HBWM@91061|Bacilli,1ZQFB@1386|Bacillus	91061|Bacilli	E	Acetylornithine deacetylase	argE	-	-	ko:K20895	ko00730,ko01100,map00730,map01100	-	R11313	RC00197	ko00000,ko00001,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_3716884_3	1501230.ET33_15230	2.05e-26	112.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,4HCED@91061|Bacilli,26TKX@186822|Paenibacillaceae	91061|Bacilli	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
HKD3_k127_3720753_1	1117379.BABA_11096	1.183e-74	258.0	COG1277@1|root,COG1277@2|Bacteria,1V6DZ@1239|Firmicutes,4HFY3@91061|Bacilli,1ZCE6@1386|Bacillus	91061|Bacilli	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD3_k127_3720753_0	1461580.CCAS010000046_gene3442	1.423e-103	343.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1ZE3A@1386|Bacillus	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Hydrolase_3,PRA-PH
HKD3_k127_3720753_2	1120973.AQXL01000100_gene1129	3.374e-22	107.0	COG5542@1|root,COG5542@2|Bacteria,1V7KR@1239|Firmicutes,4HQF2@91061|Bacilli,279J3@186823|Alicyclobacillaceae	91061|Bacilli	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
HKD3_k127_3724530_13	574376.BAMA_00445	1.364e-12	68.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,1ZB6N@1386|Bacillus	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HKD3_k127_3724530_0	574376.BAMA_00450	2.411e-212	664.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1ZCXW@1386|Bacillus	91061|Bacilli	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
HKD3_k127_3724530_1	1169144.KB910948_gene3599	8.855e-195	610.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD3_k127_3724530_4	1169144.KB910948_gene3600	7.507e-168	533.0	COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,1ZBYA@1386|Bacillus	91061|Bacilli	K	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain	cggR	-	-	ko:K05311	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
HKD3_k127_3724530_12	1169144.KB910948_gene3601	9.623e-22	99.0	COG0695@1|root,COG0695@2|Bacteria,1VHHY@1239|Firmicutes,4HQ4Z@91061|Bacilli,1ZIXQ@1386|Bacillus	91061|Bacilli	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
HKD3_k127_3724530_7	1405.DJ92_2188	1.683e-131	432.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,1ZBKU@1386|Bacillus	91061|Bacilli	K	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD3_k127_3724530_8	315749.Bcer98_3694	1.414e-108	354.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,1ZARS@1386|Bacillus	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD3_k127_3724530_11	1382358.JHVN01000016_gene533	2.566e-31	125.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKKW@91061|Bacilli,21VUD@150247|Anoxybacillus	91061|Bacilli	G	PTS HPr component phosphorylation site	crh	-	-	ko:K11184	-	-	-	-	ko00000	-	-	-	PTS-HPr
HKD3_k127_3724530_3	574375.BAGA_12045	1.454e-172	544.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus	91061|Bacilli	K	May be required for sporulation	whiA	GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
HKD3_k127_3724530_6	574375.BAGA_12050	1.187e-163	519.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,1ZB2R@1386|Bacillus	91061|Bacilli	S	Required for morphogenesis under gluconeogenic growth conditions	yvcK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
HKD3_k127_3724530_5	574376.BAMA_00520	1.572e-167	529.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,1ZCWE@1386|Bacillus	91061|Bacilli	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HKD3_k127_3724530_9	315749.Bcer98_3699	2.765e-75	254.0	COG1051@1|root,COG1051@2|Bacteria,1V3BX@1239|Firmicutes,4HGE6@91061|Bacilli,1ZFT4@1386|Bacillus	91061|Bacilli	F	Nudix hydrolase	yvcI	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD3_k127_3724530_2	1405.DJ92_2217	1.739e-182	574.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_3724530_10	315730.BcerKBAB4_4952	5.045e-52	187.0	COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yvcD	-	-	-	-	-	-	-	-	-	-	-	HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8
HKD3_k127_3726691_3	1169144.KB910925_gene102	9.934e-108	356.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,1ZC5Q@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_3726691_5	315730.BcerKBAB4_1509	9e-26	108.0	2E93T@1|root,333CR@2|Bacteria,1VFQW@1239|Firmicutes,4HPTY@91061|Bacilli,1ZISY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3726691_1	1169144.KB910925_gene104	1.37e-131	425.0	COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus	91061|Bacilli	L	5'3' exonuclease	ypcP	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
HKD3_k127_3726691_2	1405.DJ92_4227	4.948e-118	385.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,1ZANF@1386|Bacillus	91061|Bacilli	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD3_k127_3726691_6	1196029.ALIM01000023_gene445	4.299e-24	104.0	2E0UC@1|root,32WBV@2|Bacteria,1VDJ2@1239|Firmicutes,4HKXT@91061|Bacilli,1ZJ5C@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2533)	ypbS	-	-	-	-	-	-	-	-	-	-	-	DUF2533
HKD3_k127_3726691_0	315730.BcerKBAB4_1494	0.0	1238.0	COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus	91061|Bacilli	S	Dynamin family	ypbR	GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529	-	-	-	-	-	-	-	-	-	-	Dynamin_N
HKD3_k127_3726691_4	997296.PB1_13649	3.038e-55	198.0	COG1755@1|root,COG1755@2|Bacteria,1V6IY@1239|Firmicutes,4HIFN@91061|Bacilli,1ZGT0@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ypbQ	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
HKD3_k127_3726691_7	272558.10173231	2.008e-10	61.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus	91061|Bacilli	Q	Naringenin-chalcone synthase	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
HKD3_k127_3737144_3	574375.BAGA_21800	3.673e-65	225.0	COG0276@1|root,COG0276@2|Bacteria,1VUS3@1239|Firmicutes,4HVPS@91061|Bacilli,1ZQX5@1386|Bacillus	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH1	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
HKD3_k127_3737144_1	1169144.KB910927_gene1415	6.738e-193	605.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,4HAXT@91061|Bacilli,1ZDGX@1386|Bacillus	91061|Bacilli	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
HKD3_k127_3737144_0	1169144.KB910927_gene1416	6.953e-308	957.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	pbpF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.4.1.129,3.4.16.4	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_3737144_2	1169144.KB910927_gene1445	1.838e-99	330.0	COG2217@1|root,COG2217@2|Bacteria,1UHSD@1239|Firmicutes,4IS85@91061|Bacilli,1ZS2B@1386|Bacillus	91061|Bacilli	P	EcsC protein family	ecsC	-	-	-	-	-	-	-	-	-	-	-	EcsC
HKD3_k127_3737144_4	1396.DJ87_3633	2.184e-23	102.0	COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,1ZBQG@1386|Bacillus	91061|Bacilli	U	ABC transporter	ecsB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	EcsB
HKD3_k127_3755222_5	1169144.KB910939_gene2823	1.217e-139	449.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZDIH@1386|Bacillus	91061|Bacilli	S	amidohydrolase	-	-	-	ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_3755222_8	265729.GS18_0218395	6.546e-110	362.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,1ZB4Z@1386|Bacillus	91061|Bacilli	M	Belongs to the nlpA lipoprotein family	metQ_3	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD3_k127_3755222_3	1347369.CCAD010000087_gene1866	1.076e-151	485.0	COG0656@1|root,COG0656@2|Bacteria,1TSG5@1239|Firmicutes,4HAMT@91061|Bacilli,1ZEPD@1386|Bacillus	91061|Bacilli	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_3755222_14	1536772.R70723_27595	1.311e-13	80.0	2EAZJ@1|root,3350E@2|Bacteria,1VGFD@1239|Firmicutes,4HNX8@91061|Bacilli,26QS3@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3153
HKD3_k127_3755222_12	315749.Bcer98_2240	2.997e-23	102.0	2DPDU@1|root,331PB@2|Bacteria,1VFH2@1239|Firmicutes,4HQIZ@91061|Bacilli,1ZJZI@1386|Bacillus	91061|Bacilli	-	-	yodI	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3755222_10	1405.DJ92_552	1.153e-61	220.0	COG0500@1|root,COG2226@2|Bacteria,1V4RW@1239|Firmicutes,4HIF0@91061|Bacilli,1ZE3P@1386|Bacillus	91061|Bacilli	Q	Methyltransferase	yodH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
HKD3_k127_3755222_1	315749.Bcer98_2242	1.976e-244	766.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
HKD3_k127_3755222_0	574376.BAMA_20465	3.945e-306	943.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,1ZBVV@1386|Bacillus	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD3_k127_3755222_13	1117379.BABA_10561	5.025e-16	81.0	COG1396@1|root,COG1396@2|Bacteria,1UWCU@1239|Firmicutes,4I3XD@91061|Bacilli,1ZK0M@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD3_k127_3755222_11	1396.DJ87_2318	2.283e-55	201.0	COG1713@1|root,COG1713@2|Bacteria,1V44H@1239|Firmicutes,4HH8H@91061|Bacilli,1ZIQV@1386|Bacillus	91061|Bacilli	H	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD3_k127_3755222_9	1123405.AUMM01000043_gene2613	1.114e-88	294.0	COG0225@1|root,COG0225@2|Bacteria,1V1MJ@1239|Firmicutes,4HG4U@91061|Bacilli,26PMJ@186821|Sporolactobacillaceae	91061|Bacilli	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
HKD3_k127_3755222_7	1169144.KB910952_gene3188	3.371e-120	389.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1ZBFK@1386|Bacillus	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
HKD3_k127_3755222_6	1169144.KB910952_gene3189	1.004e-126	409.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus	91061|Bacilli	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HKD3_k127_3755222_2	1169144.KB910952_gene3190	2.427e-198	625.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HDIU@91061|Bacilli,1ZPZ5@1386|Bacillus	91061|Bacilli	E	COG4177 ABC-type branched-chain amino acid transport system, permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD3_k127_3755222_4	1169144.KB910952_gene3191	3.021e-140	449.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,1ZBP3@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HKD3_k127_3761874_2	1395513.P343_06715	3.35e-75	261.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,4HBPD@91061|Bacilli,26PTD@186821|Sporolactobacillaceae	91061|Bacilli	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HKD3_k127_3761874_0	865861.AZSU01000006_gene1354	2.69e-131	424.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,36E73@31979|Clostridiaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD3_k127_3761874_1	345219.Bcoa_0949	1.852e-99	338.0	COG2508@1|root,COG2508@2|Bacteria,1UJJU@1239|Firmicutes,4HD4P@91061|Bacilli	91061|Bacilli	QT	Transcriptional regulator	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
HKD3_k127_3761874_3	1444306.JFZC01000012_gene2045	9.122e-32	126.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,26PJV@186821|Sporolactobacillaceae	91061|Bacilli	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HKD3_k127_3790000_3	1405.DJ92_1007	1.731e-56	201.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus	91061|Bacilli	M	Penicillin-binding Protein	pbpB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08724	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD3_k127_3790000_4	1396.DJ87_1011	2.799e-25	109.0	COG4839@1|root,COG4839@2|Bacteria	2|Bacteria	D	cell division protein FtsL	ftsL	-	-	-	-	-	-	-	-	-	-	-	DivIC
HKD3_k127_3790000_1	1169144.KB910924_gene484	9.302e-168	530.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,1ZCHN@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD3_k127_3790000_0	1396.DJ87_1009	8.732e-185	592.0	COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus	91061|Bacilli	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HKD3_k127_3790000_2	1169144.KB910924_gene486	6.059e-98	327.0	COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZFJY@1386|Bacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15110	ApbA,ApbA_C
HKD3_k127_3790000_5	260799.BAS3772	0.0008195	42.0	COG0454@1|root,COG0454@2|Bacteria,1V259@1239|Firmicutes,4HFSD@91061|Bacilli,1ZFN4@1386|Bacillus	91061|Bacilli	K	n-acetyltransferase	ylbP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
HKD3_k127_3815408_1	666686.B1NLA3E_08505	5.607e-126	405.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli,1ZBCJ@1386|Bacillus	91061|Bacilli	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD3_k127_3815408_2	1294265.JCM21738_1549	1.538e-80	271.0	COG0782@1|root,COG0782@2|Bacteria	2|Bacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD3_k127_3815408_0	1321778.HMPREF1982_04601	3.564e-295	913.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,267ZV@186813|unclassified Clostridiales	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HKD3_k127_3824809_2	666686.B1NLA3E_02595	2.352e-70	240.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD3_k127_3824809_3	1382358.JHVN01000001_gene1028	3.403e-63	228.0	COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli,21VM2@150247|Anoxybacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_3824809_1	315749.Bcer98_3255	4.794e-100	330.0	COG1566@1|root,COG1566@2|Bacteria,1V1F5@1239|Firmicutes,4HG5R@91061|Bacilli,1ZQZ8@1386|Bacillus	91061|Bacilli	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	emrA	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD3_k127_3824809_0	1396.DJ87_310	3.877e-218	690.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	yhcA	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
HKD3_k127_3836945_2	1305836.AXVE01000011_gene566	4.838e-61	212.0	COG2141@1|root,COG2141@2|Bacteria,1TW8W@1239|Firmicutes,4HBIF@91061|Bacilli,26DCC@186818|Planococcaceae	91061|Bacilli	C	Luciferase-like monooxygenase	msuD	-	1.14.14.35	ko:K17228	ko00920,map00920	-	R10203	RC02556,RC03080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HKD3_k127_3836945_0	1340434.AXVA01000015_gene610	3.782e-162	514.0	COG0189@1|root,COG0189@2|Bacteria,1TSHN@1239|Firmicutes,4HBFG@91061|Bacilli,1ZDEU@1386|Bacillus	91061|Bacilli	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
HKD3_k127_3836945_1	1405.DJ92_548	1.172e-112	379.0	COG2304@1|root,COG2304@2|Bacteria,1VM0M@1239|Firmicutes,4IBR2@91061|Bacilli,1ZHCS@1386|Bacillus	91061|Bacilli	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_3990080_7	1340434.AXVA01000003_gene2577	5.077e-31	123.0	COG4632@1|root,COG4632@2|Bacteria,1TP2R@1239|Firmicutes,4HAZ3@91061|Bacilli	91061|Bacilli	G	Exopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
HKD3_k127_3990080_5	265729.GS18_0214130	8.909e-64	226.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,1ZBJ4@1386|Bacillus	91061|Bacilli	M	biosynthesis protein	ywqC	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
HKD3_k127_3990080_4	1396.DJ87_3925	3.206e-88	296.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,1ZB83@1386|Bacillus	91061|Bacilli	D	COG0489 ATPases involved in chromosome partitioning	ywqD	-	2.7.10.2	ko:K00903	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,ParA
HKD3_k127_3990080_2	1169144.KB910944_gene2368	2.683e-96	321.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,1ZDH3@1386|Bacillus	91061|Bacilli	GM	COG4464 Capsular polysaccharide biosynthesis protein	ywqE	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD3_k127_3990080_0	235909.GK3320	4.422e-154	490.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1WERK@129337|Geobacillus	91061|Bacilli	M	Nucleotidyl transferase	gtaB	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD3_k127_3990080_3	1234664.AMRO01000071_gene2963	8.651e-94	312.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,1WGHX@129337|Geobacillus	91061|Bacilli	M	Bacterial sugar transferase	-	-	-	ko:K13012,ko:K19428	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
HKD3_k127_3990080_1	1295642.H839_17243	1.06e-141	452.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,1WGC1@129337|Geobacillus	91061|Bacilli	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
HKD3_k127_4003068_5	358681.BBR47_17410	7.703e-27	111.0	COG1215@1|root,COG1215@2|Bacteria,1V7FY@1239|Firmicutes,4HQQ4@91061|Bacilli,274AA@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_4003068_4	588581.Cpap_1402	2.061e-84	289.0	2EYR5@1|root,33IWG@2|Bacteria,1VQNW@1239|Firmicutes,24ECF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4003068_3	588581.Cpap_1402	1.293e-84	290.0	2EYR5@1|root,33IWG@2|Bacteria,1VQNW@1239|Firmicutes,24ECF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4003068_2	1392502.JNIO01000002_gene638	1.446e-149	479.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4H2Q3@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HKD3_k127_4003068_0	997296.PB1_00325	2.996e-226	708.0	COG0438@1|root,COG0438@2|Bacteria,1UMR3@1239|Firmicutes,4HDH9@91061|Bacilli	91061|Bacilli	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1,TPR_8
HKD3_k127_4003068_1	997296.PB1_00330	1.064e-188	592.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HDMN@91061|Bacilli,1ZPWM@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_1,TPR_2
HKD3_k127_4010848_3	635013.TherJR_0994	4.941e-93	318.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
HKD3_k127_4010848_0	574375.BAGA_20555	7.765e-201	636.0	COG1620@1|root,COG1620@2|Bacteria,1TRJ2@1239|Firmicutes,4HFMG@91061|Bacilli,1ZME4@1386|Bacillus	91061|Bacilli	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
HKD3_k127_4010848_1	398511.BpOF4_10975	5.204e-173	560.0	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
HKD3_k127_4010848_2	720555.BATR1942_18505	2.799e-117	384.0	COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,1ZCQ3@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	ypaH	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_4010848_4	1007103.AFHW01000002_gene4781	8.124e-69	250.0	COG2199@1|root,COG3706@2|Bacteria,1V469@1239|Firmicutes,4IQDI@91061|Bacilli	91061|Bacilli	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HKD3_k127_4010848_5	1169144.KB910928_gene1950	9.534e-54	193.0	COG1051@1|root,COG1051@2|Bacteria,1V7IW@1239|Firmicutes,4HJNX@91061|Bacilli,1ZGFY@1386|Bacillus	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_4012800_6	1385510.N781_06865	8.276e-89	298.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,4HBE0@91061|Bacilli,2YBHY@289201|Pontibacillus	91061|Bacilli	S	Region found in RelA / SpoT proteins	ywaC	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951,ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HKD3_k127_4012800_8	1340434.AXVA01000008_gene3564	1.046e-78	273.0	COG1647@1|root,COG1647@2|Bacteria,1TT4Y@1239|Firmicutes,4HIAZ@91061|Bacilli,1ZQKX@1386|Bacillus	91061|Bacilli	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
HKD3_k127_4012800_1	1274524.BSONL12_02829	7.775e-304	934.0	COG0388@1|root,COG3153@1|root,COG0388@2|Bacteria,COG3153@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus	91061|Bacilli	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yhcX	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
HKD3_k127_4012800_3	315749.Bcer98_3612	1.131e-135	437.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZMAK@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_4012800_9	1121121.KB894319_gene3834	6.715e-62	223.0	COG0454@1|root,COG0456@2|Bacteria,1TYX1@1239|Firmicutes,4IRK3@91061|Bacilli,276U0@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_4012800_5	1169144.KB910940_gene2549	3.051e-105	353.0	COG0707@1|root,COG0707@2|Bacteria,1TR07@1239|Firmicutes,4HBKJ@91061|Bacilli,1ZQUQ@1386|Bacillus	91061|Bacilli	M	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)	ugtP	GO:0003674,GO:0003824,GO:0008194,GO:0016740,GO:0016757,GO:0016758,GO:0035251,GO:0046527,GO:0047228	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD3_k127_4012800_4	720555.BATR1942_16150	1.776e-121	405.0	COG0477@1|root,COG0477@2|Bacteria,1UIYG@1239|Firmicutes,4ISX7@91061|Bacilli,1ZAWC@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	ywoD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_4012800_10	198094.BA_5255	1.752e-41	154.0	COG0011@1|root,COG0011@2|Bacteria,1VAIR@1239|Firmicutes,4HP0G@91061|Bacilli,1ZH8U@1386|Bacillus	91061|Bacilli	S	Thiamine-binding protein	yqgV	-	-	-	-	-	-	-	-	-	-	-	DUF1385,Thiamine_BP
HKD3_k127_4012800_12	224308.BSU32930	1.205e-27	115.0	2DPT3@1|root,3339Q@2|Bacteria,1VJ5A@1239|Firmicutes,4HP0F@91061|Bacilli,1ZIZE@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2573)	yusU	-	-	-	-	-	-	-	-	-	-	-	DUF2573
HKD3_k127_4012800_2	1382358.JHVN01000016_gene586	3.453e-145	465.0	COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,21WT7@150247|Anoxybacillus	91061|Bacilli	E	Proline dehydrogenase	fadM	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD3_k127_4012800_7	1169144.KB910960_gene4020	1.633e-87	297.0	COG1686@1|root,COG1686@2|Bacteria,1UUTQ@1239|Firmicutes,4I9RZ@91061|Bacilli,1ZM6A@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Peptidase_S11
HKD3_k127_4012800_13	1169144.KB910960_gene4019	1.614e-10	62.0	29TJ3@1|root,30ESC@2|Bacteria,1UCWQ@1239|Firmicutes,4IPCQ@91061|Bacilli,1ZPQM@1386|Bacillus	91061|Bacilli	S	YuzL-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YuzL
HKD3_k127_4012800_0	574375.BAGA_11525	0.0	1058.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
HKD3_k127_4030599_18	1169144.KB910953_gene3161	7.674e-08	53.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZDFA@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yitT3	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_4030599_7	574375.BAGA_10510	3.442e-62	216.0	291YW@1|root,2ZPID@2|Bacteria,1V3V6@1239|Firmicutes,4HGYJ@91061|Bacilli,1ZG6E@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2621)	yneK	-	-	-	-	-	-	-	-	-	-	-	DUF2621
HKD3_k127_4030599_6	1405.DJ92_622	3.884e-65	226.0	COG4846@1|root,COG4846@2|Bacteria,1V7C6@1239|Firmicutes,4HGXI@91061|Bacilli,1ZG68@1386|Bacillus	91061|Bacilli	O	COG4846 Membrane protein involved in cytochrome C biogenesis	yneJ	-	-	-	-	-	-	-	-	-	-	-	DUF1453
HKD3_k127_4030599_4	1169144.KB910953_gene3145	1.24e-118	386.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus	91061|Bacilli	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
HKD3_k127_4030599_5	574375.BAGA_23125	3.358e-109	359.0	COG0345@1|root,COG0345@2|Bacteria,1V4R6@1239|Firmicutes,4HI4H@91061|Bacilli,1ZC1T@1386|Bacillus	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	-	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD3_k127_4030599_11	315730.BcerKBAB4_2753	1.425e-37	146.0	2E4BW@1|root,33GRE@2|Bacteria,1VQ2J@1239|Firmicutes,4HSYI@91061|Bacilli,1ZHA9@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2512
HKD3_k127_4030599_3	315749.Bcer98_3656	1.375e-127	417.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZDQT@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD3_k127_4030599_9	1131730.BAVI_23448	1.355e-41	158.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZDQT@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD3_k127_4030599_10	315749.Bcer98_3656	8.724e-39	150.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZDQT@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD3_k127_4030599_14	315749.Bcer98_3656	4.479e-24	104.0	COG0531@1|root,COG0531@2|Bacteria,1UM4D@1239|Firmicutes,4HCVU@91061|Bacilli,1ZDQT@1386|Bacillus	91061|Bacilli	E	Spore germination protein	-	-	-	ko:K06296	-	-	-	-	ko00000,ko02000	2.A.3.9.3	-	-	Spore_permease
HKD3_k127_4030599_13	1122915.AUGY01000020_gene6461	3.843e-28	114.0	2EMM7@1|root,33F9K@2|Bacteria,1VN2S@1239|Firmicutes,4HPA1@91061|Bacilli,26ZU1@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4030599_2	315749.Bcer98_3658	2.609e-143	465.0	2DBJR@1|root,2Z9N7@2|Bacteria,1TQ49@1239|Firmicutes,4HB42@91061|Bacilli,1ZQMP@1386|Bacillus	91061|Bacilli	S	Spore germination B3/ GerAC like, C-terminal	-	-	-	ko:K06297	-	-	-	-	ko00000	-	-	-	Spore_GerAC
HKD3_k127_4030599_1	315749.Bcer98_3659	5.401e-230	722.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus	91061|Bacilli	EG	Spore germination protein	-	-	-	ko:K06295,ko:K06307	-	-	-	-	ko00000	-	-	-	GerA
HKD3_k127_4030599_12	1169144.KB910953_gene3137	6.329e-29	117.0	COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,1ZHYQ@1386|Bacillus	91061|Bacilli	S	UPF0154 protein	yneF	-	-	ko:K09976	-	-	-	-	ko00000	-	-	-	UPF0154
HKD3_k127_4030599_8	315730.BcerKBAB4_3368	8.357e-42	158.0	2EUDS@1|root,33MW4@2|Bacteria,1VHIA@1239|Firmicutes,4HSFG@91061|Bacilli,1ZEP8@1386|Bacillus	91061|Bacilli	S	Sporulation inhibitor of replication protein sirA	yneE	-	-	-	-	-	-	-	-	-	-	-	SirA
HKD3_k127_4030599_0	198094.BA_3744	0.0	1125.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,1ZBQ6@1386|Bacillus	91061|Bacilli	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
HKD3_k127_4030599_16	1236973.JCM9157_1784	8.716e-15	76.0	COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,1ZIU8@1386|Bacillus	91061|Bacilli	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
HKD3_k127_4034324_2	1460635.JCM19038_3272	0.0006817	46.0	2BM00@1|root,32FGT@2|Bacteria,1VFEX@1239|Firmicutes	1239|Firmicutes	S	YolD-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YolD
HKD3_k127_4034324_0	1243664.CAVL020000030_gene469	6.632e-41	159.0	COG1716@1|root,COG3710@1|root,COG1716@2|Bacteria,COG3710@2|Bacteria,1V87I@1239|Firmicutes,4HJ87@91061|Bacilli,1ZH5Z@1386|Bacillus	91061|Bacilli	KT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trans_reg_C
HKD3_k127_4034371_15	1340434.AXVA01000012_gene2932	3.28e-11	64.0	COG0477@1|root,COG2814@2|Bacteria,1TRXM@1239|Firmicutes,4HCK1@91061|Bacilli,1ZPZJ@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
HKD3_k127_4034371_3	796606.BMMGA3_09250	9.827e-238	743.0	COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus	91061|Bacilli	P	COG0672 High-affinity Fe2 Pb2 permease	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
HKD3_k127_4034371_13	484770.UFO1_3788	2.396e-71	250.0	COG2822@1|root,COG2822@2|Bacteria,1VCNQ@1239|Firmicutes	1239|Firmicutes	P	iron ion transport	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4034371_14	1499685.CCFJ01000043_gene2650	6.841e-65	231.0	COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,4HMA8@91061|Bacilli,1ZG6B@1386|Bacillus	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HKD3_k127_4034371_0	545693.BMQ_0863	1.22e-250	778.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HBY4@91061|Bacilli,1ZE30@1386|Bacillus	91061|Bacilli	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_4034371_12	1051501.AYTL01000004_gene3511	2.029e-73	252.0	COG1309@1|root,COG1309@2|Bacteria,1V4J3@1239|Firmicutes,4HHPI@91061|Bacilli,1ZG5D@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yvdT_1	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
HKD3_k127_4034371_10	1196029.ALIM01000030_gene857	1.173e-100	334.0	COG1414@1|root,COG1414@2|Bacteria,1TQS2@1239|Firmicutes,4HBYR@91061|Bacilli,1ZDMV@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	kipR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
HKD3_k127_4034371_9	484770.UFO1_2733	3.917e-113	374.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4H3S0@909932|Negativicutes	909932|Negativicutes	E	TIGRFAM urea amidolyase related protein	-	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
HKD3_k127_4034371_11	1196029.ALIM01000030_gene855	2.349e-93	313.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,1ZDVS@1386|Bacillus	91061|Bacilli	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
HKD3_k127_4034371_6	649747.HMPREF0083_03116	8.228e-137	438.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,4HCWD@91061|Bacilli,271VE@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the D-glutamate cyclase family	ycsI	-	-	-	-	-	-	-	-	-	-	-	DUF1445
HKD3_k127_4034371_4	1196029.ALIM01000030_gene853	3.392e-186	589.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,1ZC68@1386|Bacillus	91061|Bacilli	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD3_k127_4034371_7	1274524.BSONL12_13711	5.66e-123	398.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,1ZC6W@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0271 (lamB) family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
HKD3_k127_4034371_2	1340434.AXVA01000041_gene231	1.693e-243	763.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus	91061|Bacilli	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
HKD3_k127_4034371_5	1007103.AFHW01000122_gene615	2.697e-148	473.0	COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,26RKC@186822|Paenibacillaceae	91061|Bacilli	E	Proline dehydrogenase	fadM	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD3_k127_4034371_1	1444310.JANV01000002_gene4427	1.445e-249	778.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZCI4@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family. RocA subfamily	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD3_k127_4034371_8	1134413.ANNK01000090_gene143	1.199e-119	386.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,1ZBN8@1386|Bacillus	91061|Bacilli	S	HAD-hyrolase-like	ysaA	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD3_k127_408815_9	1285586.H131_16048	2.014e-92	308.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,4ISKA@91061|Bacilli,3IX2R@400634|Lysinibacillus	91061|Bacilli	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF,GGDEF,MASE3,MHYT,PAS_4,PAS_9
HKD3_k127_408815_8	1403313.AXBR01000022_gene2840	3.959e-117	381.0	COG0101@1|root,COG0101@2|Bacteria,1TQEI@1239|Firmicutes,4IQV0@91061|Bacilli	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD3_k127_408815_7	666686.B1NLA3E_03700	6.17e-150	479.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,1ZB56@1386|Bacillus	91061|Bacilli	P	COG1230 Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
HKD3_k127_408815_6	1195236.CTER_2272	9.518e-164	521.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3WH25@541000|Ruminococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD3_k127_408815_5	1395587.P364_0122700	9.437e-195	628.0	COG1672@1|root,COG1672@2|Bacteria,1TS03@1239|Firmicutes,4HE9S@91061|Bacilli,26VTJ@186822|Paenibacillaceae	91061|Bacilli	K	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HKD3_k127_408815_1	189426.PODO_09890	7.322e-250	772.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA8B@91061|Bacilli,26USF@186822|Paenibacillaceae	91061|Bacilli	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
HKD3_k127_408815_3	509191.AEDB02000081_gene2467	4.033e-211	659.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3WGYP@541000|Ruminococcaceae	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
HKD3_k127_408815_10	1033734.CAET01000079_gene3596	0.0004132	44.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	metB	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_408815_0	1078085.HMPREF1210_02389	1.142e-291	910.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1VUZH@1239|Firmicutes,4IT5H@91061|Bacilli,26D2P@186818|Planococcaceae	91061|Bacilli	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_9
HKD3_k127_408815_4	1196029.ALIM01000006_gene4838	1.632e-205	647.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4HBNG@91061|Bacilli,1ZBUB@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring	allB	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_408815_2	1403313.AXBR01000023_gene2545	3.804e-219	683.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBDW@91061|Bacilli,1ZC8E@1386|Bacillus	91061|Bacilli	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	pucG	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588,R10908	RC00006,RC00008,RC00018,RC03305	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD3_k127_4088946_0	198094.BA_2038	1.639e-165	527.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4H9YM@91061|Bacilli,1ZB4D@1386|Bacillus	91061|Bacilli	C	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes	namA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN
HKD3_k127_4088946_1	1304284.L21TH_0109	1.502e-51	188.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,24MVX@186801|Clostridia,36JIN@31979|Clostridiaceae	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
HKD3_k127_4088946_2	574375.BAGA_23640	8.972e-26	119.0	COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HG9F@91061|Bacilli,1ZAQN@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	ko:K08986	-	-	-	-	ko00000	-	-	-	DUF1980
HKD3_k127_4089690_9	1169144.KB910928_gene1879	2.452e-107	351.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,1ZC8X@1386|Bacillus	91061|Bacilli	M	Involved in formation and maintenance of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HKD3_k127_4089690_12	1169144.KB910928_gene1878	1.168e-59	211.0	COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNWW@91061|Bacilli,1ZGID@1386|Bacillus	91061|Bacilli	M	shape-determining protein	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
HKD3_k127_4089690_10	1169144.KB910928_gene1877	1.759e-98	325.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,1ZDSJ@1386|Bacillus	91061|Bacilli	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
HKD3_k127_4089690_4	574375.BAGA_03800	7.506e-144	458.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,1ZB5P@1386|Bacillus	91061|Bacilli	D	Belongs to the ParA family	minD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
HKD3_k127_4089690_15	441769.ABFU01000048_gene3724	2.818e-50	189.0	COG0739@1|root,COG0739@2|Bacteria,1TSQI@1239|Firmicutes,4HFC8@91061|Bacilli,1ZFJN@1386|Bacillus	91061|Bacilli	M	COG0739 Membrane proteins related to metalloendopeptidases	spoIVFA	-	-	ko:K06401	-	-	-	-	ko00000	-	-	-	Peptidase_M23
HKD3_k127_4089690_8	574375.BAGA_03790	1.233e-113	372.0	COG1994@1|root,COG1994@2|Bacteria,1V72P@1239|Firmicutes,4HJFP@91061|Bacilli,1ZQIE@1386|Bacillus	91061|Bacilli	S	Peptidase family M50	spoIVFB	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50,Peptidase_M50B
HKD3_k127_4089690_5	198094.BA_4677	1.195e-141	463.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus	91061|Bacilli	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
HKD3_k127_4089690_13	1169144.KB910928_gene1872	1.592e-56	198.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,1ZGZG@1386|Bacillus	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HKD3_k127_4089690_18	315749.Bcer98_3158	1.045e-39	150.0	COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,1ZI1F@1386|Bacillus	91061|Bacilli	J	ribosomal protein	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
HKD3_k127_4089690_16	315749.Bcer98_3157	4.526e-47	169.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,1ZGZ9@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD3_k127_4089690_14	315749.Bcer98_3156	3.853e-56	201.0	COG3290@1|root,COG3290@2|Bacteria,1V8IS@1239|Firmicutes,4HJPR@91061|Bacilli,1ZQNK@1386|Bacillus	91061|Bacilli	T	Sporulation initiation phospho-transferase B, C-terminal	spo0B	-	-	ko:K06375	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	SPOB_a,SPOB_ab
HKD3_k127_4089690_0	1169144.KB910928_gene1868	3.943e-231	720.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,1ZCM4@1386|Bacillus	91061|Bacilli	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HKD3_k127_4089690_7	1405.DJ92_1532	4.875e-127	412.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus	91061|Bacilli	E	Prephenate dehydratase	pheA	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27900	ACT,PDT
HKD3_k127_4089690_11	1405.DJ92_1530	3.441e-76	259.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,1ZGFK@1386|Bacillus	91061|Bacilli	S	small molecule binding protein (contains 3H domain)	yrxA	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
HKD3_k127_4089690_3	1405.DJ92_1529	2.565e-160	514.0	COG1104@1|root,COG1104@2|Bacteria,1TPYU@1239|Firmicutes,4HA5J@91061|Bacilli,1ZCRY@1386|Bacillus	91061|Bacilli	E	Cysteine desulfurase	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD3_k127_4089690_1	315749.Bcer98_3145	7.367e-202	640.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus	91061|Bacilli	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD3_k127_4089690_6	1382358.JHVN01000001_gene1060	2.215e-129	418.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,21VD4@150247|Anoxybacillus	91061|Bacilli	H	Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD3_k127_4089690_2	1396.DJ87_439	6.877e-194	609.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HKD3_k127_4089690_17	1169144.KB910928_gene1855	1.469e-40	156.0	COG1388@1|root,COG1388@2|Bacteria,1VETU@1239|Firmicutes,4HP2D@91061|Bacilli,1ZD0H@1386|Bacillus	91061|Bacilli	M	spore coat assembly protein SafA	safA	GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117	-	ko:K06370	-	-	-	-	ko00000	-	-	-	LysM
HKD3_k127_4212624_5	1499685.CCFJ01000046_gene3090	3.544e-41	158.0	COG1514@1|root,COG1514@2|Bacteria,1VCBK@1239|Firmicutes,4HM3V@91061|Bacilli,1ZHT8@1386|Bacillus	91061|Bacilli	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ytlP	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
HKD3_k127_4212624_0	315749.Bcer98_3365	5.902e-266	836.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 13 family	amyX	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD3_k127_4212624_2	574376.BAMA_05245	7.963e-120	389.0	COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus	91061|Bacilli	M	Phosphotransferase	ytmP	-	-	-	-	-	-	-	-	-	-	-	APH
HKD3_k127_4212624_6	1169144.KB910930_gene1702	2.792e-37	142.0	2E43M@1|root,32YZY@2|Bacteria,1VAYB@1239|Firmicutes,4HNNI@91061|Bacilli,1ZHTZ@1386|Bacillus	91061|Bacilli	S	YtzH-like protein	ytzH	-	-	-	-	-	-	-	-	-	-	-	YtzH
HKD3_k127_4212624_3	574375.BAGA_25485	1.427e-107	353.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,1ZAP2@1386|Bacillus	91061|Bacilli	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HKD3_k127_4212624_1	315730.BcerKBAB4_4529	3.873e-137	441.0	COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,1ZAYX@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_4212624_4	574376.BAMA_05175	1.506e-41	155.0	COG5584@1|root,COG5584@2|Bacteria,1VEIQ@1239|Firmicutes,4HNS2@91061|Bacilli,1ZJ31@1386|Bacillus	91061|Bacilli	S	small secreted protein	ytzB	-	-	-	-	-	-	-	-	-	-	-	PepSY
HKD3_k127_422418_0	1121346.KB899850_gene148	3.051e-188	593.0	COG0477@1|root,COG2814@2|Bacteria,1UXXX@1239|Firmicutes,4HC83@91061|Bacilli	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD3_k127_422418_3	562970.Btus_2285	7.648e-60	214.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HKD3_k127_422418_5	985665.HPL003_03320	5.692e-49	183.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HKT8@91061|Bacilli,274XD@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
HKD3_k127_422418_4	574376.BAMA_20430	2.291e-49	178.0	2E818@1|root,332FC@2|Bacteria,1VJWN@1239|Firmicutes,4HQJJ@91061|Bacilli,1ZJ08@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
HKD3_k127_422418_2	1196322.A370_02256	1.046e-101	336.0	COG2020@1|root,COG2020@2|Bacteria,1V0PB@1239|Firmicutes,24AQ6@186801|Clostridia,36I4M@31979|Clostridiaceae	186801|Clostridia	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
HKD3_k127_422418_1	1196322.A370_02257	4.986e-112	367.0	COG0789@1|root,COG0789@2|Bacteria,1V0T5@1239|Firmicutes,24DA0@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD3_k127_432141_4	315730.BcerKBAB4_4585	2.192e-46	168.0	2C5HJ@1|root,2Z812@2|Bacteria,1TQQ6@1239|Firmicutes,4HA3F@91061|Bacilli,1ZCGB@1386|Bacillus	91061|Bacilli	S	Tetraprenyl-beta-curcumene synthase	ytpB	-	4.2.3.130	ko:K16188	-	-	R10009	RC02994	ko00000,ko01000	-	-	-	DUF2600
HKD3_k127_432141_0	1169144.KB910930_gene1640	3.238e-120	390.0	COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,1ZBD1@1386|Bacillus	91061|Bacilli	I	Alpha beta hydrolase	ytpA	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
HKD3_k127_432141_1	574376.BAMA_05610	4.816e-93	307.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4HFPC@91061|Bacilli,1ZBFS@1386|Bacillus	91061|Bacilli	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	ytoA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD3_k127_432141_3	574375.BAGA_25820	1.545e-70	243.0	COG0671@1|root,COG0671@2|Bacteria,1V33Y@1239|Firmicutes,4HGAT@91061|Bacilli,1ZFPM@1386|Bacillus	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	pgpB1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_432141_2	1395513.P343_16470	1.463e-76	260.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,26PAB@186821|Sporolactobacillaceae	91061|Bacilli	M	Glycosyl transferase 4-like	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_4394866_8	796606.BMMGA3_11180	2.361e-33	132.0	COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus	91061|Bacilli	C	COG1294 Cytochrome bd-type quinol oxidase, subunit 2	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
HKD3_k127_4394866_4	1169144.KB910924_gene540	1.249e-108	355.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZC2N@1386|Bacillus	91061|Bacilli	P	COG0569 K transport systems, NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD3_k127_4394866_1	997296.PB1_11014	9.309e-172	543.0	COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus	91061|Bacilli	I	fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD3_k127_4394866_2	1117379.BABA_12061	1.585e-153	493.0	COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,1ZBZR@1386|Bacillus	91061|Bacilli	T	Histidine kinase	desK	GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
HKD3_k127_4394866_5	1117379.BABA_12056	7.115e-101	331.0	COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,1ZC1V@1386|Bacillus	91061|Bacilli	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	desR	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
HKD3_k127_4394866_6	1157490.EL26_21205	2.375e-80	268.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,4HNW0@91061|Bacilli	91061|Bacilli	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HKD3_k127_4394866_7	666686.B1NLA3E_08675	2.785e-71	245.0	COG0247@1|root,COG0247@2|Bacteria,1VUZJ@1239|Firmicutes,4HVNI@91061|Bacilli	91061|Bacilli	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
HKD3_k127_4394866_0	574376.BAMA_09250	0.0	1038.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZBCD@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD3_k127_4394866_10	574376.BAMA_09245	6.487e-22	98.0	COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,1ZIUI@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0356 family	ykzG	-	-	-	-	-	-	-	-	-	-	-	DUF1447
HKD3_k127_4394866_3	1405.DJ92_1069	1.942e-118	385.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1ZBY4@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	ykrA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
HKD3_k127_4394866_11	796606.BMMGA3_03910	5.456e-14	74.0	COG1918@1|root,COG1918@2|Bacteria,1VGV9@1239|Firmicutes,4HPQB@91061|Bacilli,1ZJ0N@1386|Bacillus	91061|Bacilli	P	COG1918 Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HKD3_k127_4394866_9	1297581.H919_11875	4.127e-32	126.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,21W1M@150247|Anoxybacillus	91061|Bacilli	P	Ferrous iron transport protein B C terminus	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	iSB619.SA_RS13395	FeoB_C,FeoB_N,Gate
HKD3_k127_45101_2	1169144.KB910936_gene1256	1.045e-08	59.0	2EQSH@1|root,33ICC@2|Bacteria,1VN5W@1239|Firmicutes,4HRDG@91061|Bacilli,1ZIX3@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_45101_1	574375.BAGA_03595	1.797e-70	240.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1ZG82@1386|Bacillus	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HKD3_k127_45101_0	1405.DJ92_1506	7.433e-316	972.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
HKD3_k127_451848_7	1461580.CCAS010000009_gene1247	5.678e-56	197.0	COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,1ZFR7@1386|Bacillus	91061|Bacilli	M	COG1247 Sortase and related acyltransferases	ywnH	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
HKD3_k127_451848_1	1461580.CCAS010000003_gene467	2.141e-233	729.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,1ZBB0@1386|Bacillus	91061|Bacilli	E	amino acid	yfnA	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_451848_9	1444310.JANV01000118_gene2037	5.514e-09	59.0	2EH08@1|root,33ASA@2|Bacteria,1VKFJ@1239|Firmicutes,4HRDY@91061|Bacilli,1ZK21@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_451848_0	1234664.AMRO01000048_gene870	4.998e-248	769.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,4HBRG@91061|Bacilli,1WG2G@129337|Geobacillus	91061|Bacilli	C	4Fe-4S dicluster domain	preA	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
HKD3_k127_451848_2	1234664.AMRO01000048_gene869	7.069e-208	654.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,1WFKH@129337|Geobacillus	91061|Bacilli	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
HKD3_k127_451848_5	1169144.KB910942_gene2636	3.613e-76	261.0	COG0515@1|root,COG0515@2|Bacteria,1V5HR@1239|Firmicutes,4HITS@91061|Bacilli,1ZR6W@1386|Bacillus	91061|Bacilli	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_451848_10	1185653.A1A1_09131	5.306e-06	55.0	COG2846@1|root,COG2846@2|Bacteria,1V439@1239|Firmicutes,4HGXC@91061|Bacilli,26F75@186818|Planococcaceae	91061|Bacilli	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD3_k127_451848_4	315730.BcerKBAB4_3250	5.603e-87	293.0	COG1028@1|root,COG1028@2|Bacteria,1V1Z9@1239|Firmicutes,4HCPI@91061|Bacilli,1ZFQF@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	yueD	-	1.1.1.320	ko:K16216	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
HKD3_k127_451848_8	1122927.KB895413_gene1845	5.8e-34	136.0	COG4244@1|root,COG4244@2|Bacteria,1VEVH@1239|Firmicutes,4HPU8@91061|Bacilli,2711N@186822|Paenibacillaceae	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_451848_6	1169144.KB910955_gene263	5.847e-57	201.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,4HHA6@91061|Bacilli,1ZFKA@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuiD	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
HKD3_k127_451848_3	1169144.KB910955_gene264	5.206e-92	306.0	COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli,1ZD78@1386|Bacillus	91061|Bacilli	S	-transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
HKD3_k127_4835038_0	666686.B1NLA3E_02750	4.684e-92	305.0	COG1366@1|root,COG3852@1|root,COG1366@2|Bacteria,COG3852@2|Bacteria,1TT64@1239|Firmicutes,4HCAK@91061|Bacilli,1ZDJS@1386|Bacillus	91061|Bacilli	T	STAS domain	rsbRD	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	HATPase_c,HisKA,STAS
HKD3_k127_4835038_2	666686.B1NLA3E_02755	1.334e-70	240.0	COG2172@1|root,COG2172@2|Bacteria,1V6Y4@1239|Firmicutes,4HIQU@91061|Bacilli,1ZG7T@1386|Bacillus	91061|Bacilli	T	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
HKD3_k127_4835038_5	1169144.KB910925_gene129	2.025e-17	83.0	2ETMY@1|root,33M5Q@2|Bacteria,1VPZB@1239|Firmicutes,4HR2S@91061|Bacilli,1ZKDZ@1386|Bacillus	91061|Bacilli	S	YppF-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YppF
HKD3_k127_4835038_3	1405.DJ92_4206	3.817e-36	141.0	29NR8@1|root,309P6@2|Bacteria,1U5F9@1239|Firmicutes,4IF6W@91061|Bacilli,1ZJ7A@1386|Bacillus	91061|Bacilli	S	YppG-like protein	yppG	-	-	-	-	-	-	-	-	-	-	-	YppG
HKD3_k127_4835038_4	574376.BAMA_14260	2.423e-27	118.0	2DP9U@1|root,3315V@2|Bacteria,1UB38@1239|Firmicutes,4IMFX@91061|Bacilli,1ZK2P@1386|Bacillus	91061|Bacilli	S	Inner spore coat protein D	cotD	-	-	ko:K06327	-	-	-	-	ko00000	-	-	-	Spore-coat_CotD
HKD3_k127_4835038_1	1396.DJ87_5405	1.63e-87	292.0	COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,1ZFYS@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0398 family	ypsA	-	-	-	-	-	-	-	-	-	-	-	DUF1273
HKD3_k127_4840521_2	1499680.CCFE01000025_gene3238	1.165e-46	169.0	COG5609@1|root,COG5609@2|Bacteria,1V6YC@1239|Firmicutes,4HIMH@91061|Bacilli,1ZH3T@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2294)	ybcI	-	-	-	-	-	-	-	-	-	-	-	DUF2294
HKD3_k127_4840521_0	1117379.BABA_15357	0.0	1119.0	COG3002@1|root,COG3002@2|Bacteria,1UWRU@1239|Firmicutes,4HAMS@91061|Bacilli,1ZCP6@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0753 family	ybcC	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
HKD3_k127_4840521_1	1131730.BAVI_06524	6.108e-198	629.0	COG1009@1|root,COG1009@2|Bacteria,1TS72@1239|Firmicutes,4HCW7@91061|Bacilli,1ZCMA@1386|Bacillus	91061|Bacilli	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	ndhF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
HKD3_k127_4840521_3	555088.DealDRAFT_0166	5.741e-33	128.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VWA
HKD3_k127_4843341_1	1396.DJ87_5250	5.428e-88	300.0	COG0457@1|root,COG0457@2|Bacteria,1V0DV@1239|Firmicutes,4HQN4@91061|Bacilli,1ZNKB@1386|Bacillus	91061|Bacilli	S	Histidine kinase	-	-	-	ko:K06361,ko:K06365,ko:K06366,ko:K06368	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	TPR_10,TPR_12,TPR_8
HKD3_k127_4843341_0	1169144.KB910949_gene3537	4.046e-91	307.0	arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,4HIRV@91061|Bacilli,1ZF0Y@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4845531_1	315749.Bcer98_0253	1.265e-115	372.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,1ZB6Z@1386|Bacillus	91061|Bacilli	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HKD3_k127_4845531_0	1169144.KB910992_gene2865	6.902e-233	726.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus	91061|Bacilli	S	permease	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	iYO844.BSU06370	Xan_ur_permease
HKD3_k127_4845531_2	574375.BAGA_24775	2.068e-37	142.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,1ZCRU@1386|Bacillus	91061|Bacilli	T	Transcriptional regulator	walR1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_4851059_1	574375.BAGA_08930	1.065e-135	435.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HCE7@91061|Bacilli,1ZC3Z@1386|Bacillus	91061|Bacilli	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD3_k127_4851059_3	697284.ERIC2_c31810	3.556e-74	254.0	COG0681@1|root,COG0681@2|Bacteria,1V2RW@1239|Firmicutes,4HG5U@91061|Bacilli,26WQY@186822|Paenibacillaceae	91061|Bacilli	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD3_k127_4851059_2	1403313.AXBR01000023_gene2642	2.748e-122	400.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HB6E@91061|Bacilli,1ZQNX@1386|Bacillus	91061|Bacilli	S	Na -dependent transporter	ybaS	-	-	-	-	-	-	-	-	-	-	-	SBF,SBF_like
HKD3_k127_4851059_0	1340434.AXVA01000024_gene3910	2.676e-147	472.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HUAD@91061|Bacilli,1ZSBU@1386|Bacillus	91061|Bacilli	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
HKD3_k127_4851059_5	315749.Bcer98_1570	1.861e-52	196.0	COG0601@1|root,COG0601@2|Bacteria,1VEBI@1239|Firmicutes,4HKXF@91061|Bacilli,1ZECG@1386|Bacillus	91061|Bacilli	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD3_k127_4851059_6	1169144.KB910990_gene1721	4.903e-30	123.0	COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus	91061|Bacilli	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,Peptidase_M1
HKD3_k127_4851059_4	1169144.KB910990_gene1721	1.151e-59	213.0	COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus	91061|Bacilli	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,Peptidase_M1
HKD3_k127_4851059_7	1307436.PBF_15204	6.196e-22	94.0	COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,1ZDMF@1386|Bacillus	91061|Bacilli	S	Hemerythrin HHE cation binding domain	XK27_04775	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF438,Hemerythrin,PAS_10
HKD3_k127_4862376_1	796606.BMMGA3_08790	6.09e-102	336.0	COG1842@1|root,COG1842@2|Bacteria,1UWCA@1239|Firmicutes,4IRM9@91061|Bacilli,1ZRVG@1386|Bacillus	91061|Bacilli	KT	PspA/IM30 family	pspA3	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
HKD3_k127_4862376_0	315730.BcerKBAB4_5231	8.148e-114	377.0	COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,1ZBJD@1386|Bacillus	91061|Bacilli	S	AI-2E family transporter	ydbI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_4868730_23	574376.BAMA_22645	2.875e-09	59.0	29WYG@1|root,30IKQ@2|Bacteria,1V4Y2@1239|Firmicutes,4HI5K@91061|Bacilli,1ZHEH@1386|Bacillus	91061|Bacilli	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
HKD3_k127_4868730_12	574375.BAGA_02465	1.521e-58	210.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_4868730_14	1169144.KB910946_gene3674	4.241e-54	196.0	2DQUB@1|root,338QT@2|Bacteria,1VEUN@1239|Firmicutes,4IS20@91061|Bacilli,1ZS0I@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AF	spoIIIAF	-	-	ko:K06395	-	-	-	-	ko00000	-	-	-	Spore_III_AF
HKD3_k127_4868730_2	1169144.KB910946_gene3675	1.813e-178	567.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,4H9UX@91061|Bacilli,1ZCFI@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
HKD3_k127_4868730_17	1169144.KB910946_gene3676	1.214e-43	162.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,4HIIH@91061|Bacilli,1ZGYV@1386|Bacillus	91061|Bacilli	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HKD3_k127_4868730_19	574376.BAMA_22620	1.081e-30	122.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,4HNK4@91061|Bacilli,1ZI0F@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HKD3_k127_4868730_8	1169144.KB910946_gene3678	5.869e-75	255.0	2CEWW@1|root,32S0Q@2|Bacteria,1VAEG@1239|Firmicutes,4HGSK@91061|Bacilli,1ZQIX@1386|Bacillus	91061|Bacilli	S	Stage III sporulation protein	spoIIIAB	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
HKD3_k127_4868730_5	574375.BAGA_02495	7.174e-141	452.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus	91061|Bacilli	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	AAA,T2SSE
HKD3_k127_4868730_20	1405.DJ92_1297	7.615e-28	115.0	2E4CX@1|root,32Z8B@2|Bacteria,1VEW3@1239|Firmicutes,4HNU3@91061|Bacilli,1ZIYG@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2619)	yqhV	-	-	-	-	-	-	-	-	-	-	-	DUF2619
HKD3_k127_4868730_6	1396.DJ87_665	7.369e-100	328.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,1ZAT9@1386|Bacillus	91061|Bacilli	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD3_k127_4868730_1	1405.DJ92_1301	7.976e-180	567.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	yqhT	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HKD3_k127_4868730_10	315730.BcerKBAB4_4052	9.132e-68	233.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,4HJ2V@91061|Bacilli,1ZG8H@1386|Bacillus	91061|Bacilli	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
HKD3_k127_4868730_13	574375.BAGA_02530	5.114e-56	199.0	29VNZ@1|root,30H6A@2|Bacteria,1V5PG@1239|Firmicutes,4HJV5@91061|Bacilli,1ZBD8@1386|Bacillus	91061|Bacilli	S	Conserved membrane protein YqhR	yqhR	-	-	-	-	-	-	-	-	-	-	-	YqhR
HKD3_k127_4868730_3	574375.BAGA_02535	1.742e-160	511.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H9KN@91061|Bacilli,1ZBXJ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1385)	yqhQ	-	-	-	-	-	-	-	-	-	-	-	DUF1385
HKD3_k127_4868730_18	1169144.KB910946_gene3686	3.355e-31	126.0	2BYG1@1|root,33M6N@2|Bacteria,1U3TH@1239|Firmicutes,4IC1U@91061|Bacilli,1ZIYH@1386|Bacillus	91061|Bacilli	-	-	yqhP	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4868730_9	574376.BAMA_22565	1.582e-74	254.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,1ZFKR@1386|Bacillus	91061|Bacilli	K	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon	mntR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD3_k127_4868730_0	574376.BAMA_22560	6.503e-189	593.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,4HACB@91061|Bacilli,1ZBPU@1386|Bacillus	91061|Bacilli	L	Spore photoproduct lyase	splB	GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD3_k127_4868730_11	260799.BAS4110	7.639e-66	234.0	COG3266@1|root,COG3266@2|Bacteria,1UHTH@1239|Firmicutes,4IS96@91061|Bacilli,1ZM6V@1386|Bacillus	91061|Bacilli	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4868730_4	1169144.KB910946_gene3692	2.233e-142	455.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,1ZBG2@1386|Bacillus	91061|Bacilli	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation	lipM	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HKD3_k127_4868730_15	471223.GWCH70_2356	2.105e-47	174.0	COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,1WGA1@129337|Geobacillus	91061|Bacilli	P	Rhodanese Homology Domain	yqhL	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD3_k127_4868730_7	634956.Geoth_2866	2.266e-82	281.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1WFP3@129337|Geobacillus	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	ykrA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
HKD3_k127_4868730_16	373994.Riv7116_2025	2.116e-46	175.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HQBR@1161|Nostocales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HKD3_k127_4868730_22	260799.BAS4127	1.476e-18	87.0	29TQ7@1|root,30EYB@2|Bacteria,1UD4V@1239|Firmicutes,4IDXS@91061|Bacilli,1ZNG2@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4868795_2	1403313.AXBR01000027_gene5221	7.505e-33	128.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	prtS	-	3.4.21.110,3.4.21.96	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5
HKD3_k127_4868795_3	997296.PB1_08117	1.357e-24	107.0	COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,1ZJ1K@1386|Bacillus	91061|Bacilli	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HKD3_k127_4868795_1	1403313.AXBR01000027_gene5220	1.257e-36	141.0	2AGCB@1|root,316I0@2|Bacteria,1V7QK@1239|Firmicutes,4HJCW@91061|Bacilli	91061|Bacilli	S	ATP synthase	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
HKD3_k127_4868795_0	1403313.AXBR01000027_gene5219	1.208e-116	378.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,1ZB02@1386|Bacillus	91061|Bacilli	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HKD3_k127_4868795_4	1403313.AXBR01000027_gene5218	7.315e-11	63.0	COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,1ZIWP@1386|Bacillus	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD3_k127_4873267_4	574375.BAGA_07730	1.07e-19	92.0	COG2318@1|root,COG2318@2|Bacteria,1V70V@1239|Firmicutes,4HJAI@91061|Bacilli,1ZIMU@1386|Bacillus	91061|Bacilli	S	DinB superfamily	yuaE	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD3_k127_4873267_0	1169144.KB910951_gene3313	1.238e-288	893.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,1ZD3W@1386|Bacillus	91061|Bacilli	E	oligoendopeptidase	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
HKD3_k127_4873267_1	697284.ERIC2_c07340	7.652e-90	301.0	COG1741@1|root,COG1741@2|Bacteria,1TSV4@1239|Firmicutes,4HB1G@91061|Bacilli,26SW9@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HKD3_k127_4873267_3	574376.BAMA_13215	1.25e-53	192.0	COG1846@1|root,COG1846@2|Bacteria,1V6EE@1239|Firmicutes,4HJ8T@91061|Bacilli,1ZGC6@1386|Bacillus	91061|Bacilli	K	transcriptional	ykvE	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
HKD3_k127_4873267_2	574375.BAGA_07715	4.565e-73	259.0	COG4191@1|root,COG4191@2|Bacteria,1VS6S@1239|Firmicutes,4HV7J@91061|Bacilli,1ZS26@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K13532	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3149,HATPase_c,HisKA,dCache_1
HKD3_k127_4878502_0	574376.BAMA_21235	4.051e-148	473.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,1ZBEH@1386|Bacillus	91061|Bacilli	C	Inorganic pyrophosphatase	ppaC	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DHH,DHHA2
HKD3_k127_4878502_5	926560.KE387027_gene1023	2.59e-35	149.0	COG1215@1|root,COG1215@2|Bacteria,1WJB5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
HKD3_k127_4878502_2	574376.BAMA_07650	1.957e-97	331.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HHFU@91061|Bacilli,1ZPX5@1386|Bacillus	91061|Bacilli	T	Histidine kinase	baeS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
HKD3_k127_4878502_3	574375.BAGA_19535	2.273e-96	319.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHIC@91061|Bacilli,1ZC3A@1386|Bacillus	91061|Bacilli	KT	LuxR family transcriptional regulator	yfiK	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
HKD3_k127_4878502_1	1169144.KB910935_gene2008	1.449e-138	446.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HDH1@91061|Bacilli,1ZPYP@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	drrA	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
HKD3_k127_4878502_4	1169144.KB910935_gene2007	5.254e-53	192.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1V8HM@1239|Firmicutes,4IPM5@91061|Bacilli,1ZRCG@1386|Bacillus	91061|Bacilli	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD3_k127_4890639_4	1169144.KB910937_gene1073	3.755e-18	85.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HBE4@91061|Bacilli,1ZD5Z@1386|Bacillus	91061|Bacilli	M	Spore Coat	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
HKD3_k127_4890639_1	260799.BAS1901	1.431e-97	321.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,4HA51@91061|Bacilli,1ZQ9I@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD3_k127_4890639_2	1118054.CAGW01000059_gene2053	1.418e-77	267.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,4IQZI@91061|Bacilli,276K9@186822|Paenibacillaceae	91061|Bacilli	E	branched-chain amino acid	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
HKD3_k127_4890639_3	268407.PWYN_21210	2.219e-19	91.0	COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HRBI@91061|Bacilli,2770D@186822|Paenibacillaceae	91061|Bacilli	S	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
HKD3_k127_4890639_0	574375.BAGA_17890	3.354e-113	369.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,1ZCSW@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_490463_2	1220589.CD32_18700	2.63e-56	202.0	COG1309@1|root,COG1309@2|Bacteria,1V34K@1239|Firmicutes,4HITW@91061|Bacilli,3IYFF@400634|Lysinibacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_490463_0	1174504.AJTN02000001_gene2835	4.073e-153	492.0	COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,1ZCYR@1386|Bacillus	91061|Bacilli	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_490463_1	1449342.JQMR01000001_gene2079	1.134e-100	333.0	COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,27H5B@186828|Carnobacteriaceae	91061|Bacilli	V	ATPases associated with a variety of cellular activities	hrtA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_490463_3	562970.Btus_2207	5.107e-12	66.0	COG5516@1|root,COG5516@2|Bacteria,1V3TV@1239|Firmicutes,4HI6M@91061|Bacilli,278Q2@186823|Alicyclobacillaceae	91061|Bacilli	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
HKD3_k127_4909421_9	315730.BcerKBAB4_4084	2.007e-60	211.0	2CH5D@1|root,2Z821@2|Bacteria,1TS45@1239|Firmicutes,4HCE9@91061|Bacilli,1ZAXP@1386|Bacillus	91061|Bacilli	S	Bacterial protein YqhG of unknown function	yqhG	-	-	-	-	-	-	-	-	-	-	-	YqhG
HKD3_k127_4909421_5	634956.Geoth_2381	1.7e-116	386.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli	91061|Bacilli	C	glycerol dehydrogenase	ypjH	-	-	ko:K08317	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
HKD3_k127_4909421_3	198467.NP92_12690	7.094e-134	431.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,21W9F@150247|Anoxybacillus	91061|Bacilli	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD3_k127_4909421_6	1345697.M493_07715	1.214e-104	343.0	COG2011@1|root,COG2011@2|Bacteria,1TSJS@1239|Firmicutes,4HAZD@91061|Bacilli,1WFD0@129337|Geobacillus	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	metP_2	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
HKD3_k127_4909421_2	634956.Geoth_1662	9.756e-157	501.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1WE4R@129337|Geobacillus	91061|Bacilli	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
HKD3_k127_4909421_4	198467.NP92_12690	1.069e-123	402.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,21W9F@150247|Anoxybacillus	91061|Bacilli	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD3_k127_4909421_12	260799.BAS4134	3.921e-34	132.0	29T2N@1|root,30E95@2|Bacteria,1UC9Q@1239|Firmicutes,4INS5@91061|Bacilli,1ZNV8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4909421_18	1396.DJ87_630	7.464e-19	88.0	2EKZB@1|root,33ENU@2|Bacteria,1VM73@1239|Firmicutes,4HR7F@91061|Bacilli,1ZJY6@1386|Bacillus	91061|Bacilli	S	YqzE-like protein	yqzE	-	-	-	-	-	-	-	-	-	-	-	YqzE
HKD3_k127_4909421_10	1169144.KB910946_gene3716	3.372e-54	194.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,1ZHX4@1386|Bacillus	91061|Bacilli	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HKD3_k127_4909421_17	545693.BMQ_4490	3.264e-19	93.0	COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli,1ZIZV@1386|Bacillus	91061|Bacilli	U	COG4940 Competence protein ComGF	comGF	-	-	ko:K02248	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComGF,N_methyl
HKD3_k127_4909421_20	574376.BAMA_22445	1.416e-10	67.0	2BVCJ@1|root,32QSM@2|Bacteria,1U8MF@1239|Firmicutes,4IIJF@91061|Bacilli,1ZNN2@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4909421_14	1169144.KB910946_gene3720	2.517e-31	130.0	COG4970@1|root,COG4970@2|Bacteria,1VBS8@1239|Firmicutes,4HKPK@91061|Bacilli,1ZJ1Q@1386|Bacillus	91061|Bacilli	NU	COG2165 Type II secretory pathway, pseudopilin PulG	comGD	-	-	ko:K02246	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	N_methyl
HKD3_k127_4909421_15	315749.Bcer98_2926	1.548e-29	121.0	COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,1ZIXK@1386|Bacillus	91061|Bacilli	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	N_methyl
HKD3_k127_4909421_8	574376.BAMA_22430	2.714e-90	308.0	COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus	91061|Bacilli	NU	COG1459 Type II secretory pathway, component PulF	comGB	-	-	ko:K02244	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.14.1	-	-	T2SSF
HKD3_k127_4909421_1	1169144.KB910946_gene3723	3.388e-159	507.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZBK5@1386|Bacillus	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	comGA	-	-	ko:K02243	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.14.1	-	-	T2SSE
HKD3_k127_4909421_7	574376.BAMA_22420	1.054e-102	338.0	COG2345@1|root,COG2345@2|Bacteria,1UYQM@1239|Firmicutes,4HFSS@91061|Bacilli,1ZR9X@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase,HTH_20
HKD3_k127_4909421_13	1396.DJ87_619	1.264e-33	131.0	2E1GI@1|root,32WUX@2|Bacteria,1VA9F@1239|Firmicutes,4HMDJ@91061|Bacilli,1ZQN7@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2626)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2626
HKD3_k127_4909421_16	574376.BAMA_22400	1.623e-19	91.0	29T20@1|root,30E8H@2|Bacteria,1UC8Z@1239|Firmicutes,4INRB@91061|Bacilli,1ZNU1@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3912)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3912
HKD3_k127_4909421_11	574376.BAMA_22395	2.412e-39	151.0	2BNHK@1|root,32H60@2|Bacteria,1UBPX@1239|Firmicutes,4IN4S@91061|Bacilli,1ZMUD@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4909421_0	1169144.KB910968_gene3348	8.659e-160	511.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD3_k127_4924217_6	315730.BcerKBAB4_1259	2.693e-68	232.0	COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli,1ZB8C@1386|Bacillus	91061|Bacilli	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
HKD3_k127_4924217_10	574376.BAMA_13255	2.386e-25	106.0	COG4873@1|root,COG4873@2|Bacteria,1VF7M@1239|Firmicutes,4HPMH@91061|Bacilli,1ZIXH@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ykvS	-	-	-	-	-	-	-	-	-	-	-	DUF2187
HKD3_k127_4924217_7	315749.Bcer98_1069	1.317e-53	195.0	COG0406@1|root,COG0406@2|Bacteria,1V5MD@1239|Firmicutes,4HHT5@91061|Bacilli,1ZIPX@1386|Bacillus	91061|Bacilli	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HKD3_k127_4924217_12	1243664.CAVL020000025_gene1655	8.983e-16	78.0	2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes,4HR2E@91061|Bacilli,1ZIUC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4924217_13	198094.BA_1368	3.088e-08	60.0	29SSB@1|root,30DY9@2|Bacteria,1UBW4@1239|Firmicutes,4INBQ@91061|Bacilli,1ZN78@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4924217_9	1042163.BRLA_c024320	1.678e-37	145.0	COG1780@1|root,COG1780@2|Bacteria,1V9T1@1239|Firmicutes,4HJ0M@91061|Bacilli,26YGP@186822|Paenibacillaceae	91061|Bacilli	F	Probably involved in ribonucleotide reductase function	nrdI	GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564	-	ko:K03647	-	-	-	-	ko00000	-	-	-	Flavodoxin_NdrI
HKD3_k127_4924217_0	198094.BA_1371	0.0	1206.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,1ZANT@1386|Bacillus	91061|Bacilli	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdE	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iYO844.BSU17380	RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN
HKD3_k127_4924217_2	574376.BAMA_13295	1.668e-172	544.0	COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,1ZBBM@1386|Bacillus	91061|Bacilli	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdF	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iYO844.BSU17390	Ribonuc_red_sm
HKD3_k127_4924217_3	218284.CCDN010000001_gene492	2.188e-155	495.0	COG0604@1|root,COG0604@2|Bacteria,1UYWR@1239|Firmicutes,4HDC6@91061|Bacilli,1ZBTU@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD3_k127_4924217_5	1121091.AUMP01000001_gene565	1.361e-91	307.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HB38@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD3_k127_4924217_1	1405.DJ92_633	5.085e-192	613.0	COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus	91061|Bacilli	E	arginine degradation protein	rocB	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M20
HKD3_k127_4924217_4	1169144.KB910951_gene3289	5.788e-97	328.0	COG1266@1|root,COG1266@2|Bacteria,1V26Z@1239|Firmicutes,4HG1I@91061|Bacilli,1ZJH6@1386|Bacillus	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_4924217_8	315749.Bcer98_1086	1.014e-43	162.0	2DTDI@1|root,33JVF@2|Bacteria,1VPY3@1239|Firmicutes,4HS2E@91061|Bacilli,1ZPF3@1386|Bacillus	91061|Bacilli	S	SseB protein N-terminal domain	sseB	-	-	-	-	-	-	-	-	-	-	-	SseB
HKD3_k127_4937471_5	1169144.KB910930_gene1691	7.511e-30	120.0	2DDUZ@1|root,2ZJDI@2|Bacteria,1W2NR@1239|Firmicutes,4HZRM@91061|Bacilli,1ZJYK@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2553)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2553
HKD3_k127_4937471_6	1169144.KB910930_gene1692	2.017e-24	102.0	2EJ4P@1|root,33CVX@2|Bacteria,1VMH9@1239|Firmicutes,4HSGS@91061|Bacilli,1ZIVZ@1386|Bacillus	91061|Bacilli	S	Sporulation protein Cse60	yteV	-	-	-	-	-	-	-	-	-	-	-	Spore_Cse60
HKD3_k127_4937471_1	1169144.KB910930_gene1694	2.667e-210	662.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus	91061|Bacilli	S	HI0933-like protein	ytfP	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD3_k127_4937471_0	315749.Bcer98_3370	8.191e-249	777.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	ytgP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
HKD3_k127_4937471_3	1169144.KB910930_gene1696	2.417e-117	382.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,1ZCAM@1386|Bacillus	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_4937471_4	198094.BA_4957	1.503e-35	136.0	COG1349@1|root,COG1349@2|Bacteria,1VG5N@1239|Firmicutes,4HNPQ@91061|Bacilli,1ZHT3@1386|Bacillus	91061|Bacilli	K	COG1349 Transcriptional regulators of sugar metabolism	ytzE	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
HKD3_k127_4937471_2	1396.DJ87_168	5.363e-208	655.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus	91061|Bacilli	E	Dipeptidase	ytjP	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_4937471_7	471223.GWCH70_2755	4.363e-13	73.0	COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1WEXZ@129337|Geobacillus	91061|Bacilli	EGP	Nucleoside H+ symporter	ywbF	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
HKD3_k127_4940027_1	1117379.BABA_17682	2.952e-79	271.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,1ZIP6@1386|Bacillus	91061|Bacilli	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD3_k127_4940027_3	1117379.BABA_17677	7.296e-54	195.0	COG4097@1|root,COG4097@2|Bacteria,1VAMR@1239|Firmicutes,4I89N@91061|Bacilli,1ZGMH@1386|Bacillus	91061|Bacilli	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
HKD3_k127_4940027_2	1423321.AS29_18525	2.059e-72	251.0	COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus	91061|Bacilli	P	COG0672 High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
HKD3_k127_4940027_0	315730.BcerKBAB4_1651	7.9e-147	475.0	COG2733@1|root,COG2733@2|Bacteria,1TS8F@1239|Firmicutes,4HC8U@91061|Bacilli,1ZCND@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD3_k127_4948108_2	1169144.KB910966_gene3447	1.656e-90	306.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,1ZQ44@1386|Bacillus	91061|Bacilli	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD3_k127_4948108_0	386043.lwe1057	2.575e-140	453.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,26J5U@186820|Listeriaceae	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_4948108_9	1235794.C811_00148	2.297e-09	63.0	COG2076@1|root,COG2076@2|Bacteria,2HV51@201174|Actinobacteria,4CWBN@84998|Coriobacteriia	84998|Coriobacteriia	P	Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_4948108_7	574375.BAGA_29230	7.564e-42	156.0	COG2076@1|root,COG2076@2|Bacteria,1VFDI@1239|Firmicutes,4IN6X@91061|Bacilli,1ZMYB@1386|Bacillus	91061|Bacilli	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_4948108_6	1382358.JHVN01000015_gene661	3.805e-43	169.0	COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,21V25@150247|Anoxybacillus	91061|Bacilli	ET	Bacterial periplasmic substrate-binding proteins	tcyA	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
HKD3_k127_4948108_4	1121342.AUCO01000004_gene715	1.992e-61	233.0	COG5617@1|root,COG5617@2|Bacteria,1V776@1239|Firmicutes,24J3S@186801|Clostridia,36JSM@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
HKD3_k127_4948108_3	1169144.KB910991_gene2737	1.441e-61	235.0	COG4713@1|root,COG4713@2|Bacteria,1TU1C@1239|Firmicutes,4I4BS@91061|Bacilli,1ZNBR@1386|Bacillus	91061|Bacilli	M	Predicted membrane protein (DUF2142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
HKD3_k127_4948108_1	1169144.KB910991_gene2738	1.108e-116	379.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,4HDKY@91061|Bacilli,1ZS2D@1386|Bacillus	91061|Bacilli	S	Glycosyl transferase family 2	ycbB	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
HKD3_k127_4948108_8	1169144.KB910991_gene2739	1.567e-35	139.0	2DNVW@1|root,32ZEJ@2|Bacteria,1UPVJ@1239|Firmicutes,4IVBS@91061|Bacilli	91061|Bacilli	S	Uncharacterized conserved protein (DUF2304)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304
HKD3_k127_4948108_5	1169144.KB910966_gene3444	3.234e-57	204.0	COG0438@1|root,COG0438@2|Bacteria,1VE9Z@1239|Firmicutes,4I280@91061|Bacilli,1ZEX0@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_4972076_5	1385511.N783_21810	0.0002559	44.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,2Y934@289201|Pontibacillus	91061|Bacilli	FP	Exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD3_k127_4972076_0	1405.DJ92_1090	0.0	1107.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,1ZB38@1386|Bacillus	91061|Bacilli	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD3_k127_4972076_2	1169144.KB910924_gene556	2.785e-119	389.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4HC8Q@91061|Bacilli,1ZB99@1386|Bacillus	91061|Bacilli	S	Metallophosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,TAT_signal
HKD3_k127_4972076_1	1396.DJ87_870	2.695e-126	407.0	COG1028@1|root,COG1028@2|Bacteria,1TPDB@1239|Firmicutes,4HAKR@91061|Bacilli,1ZDEP@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
HKD3_k127_4972076_4	315730.BcerKBAB4_1353	1.963e-06	51.0	29SBI@1|root,30DG2@2|Bacteria,1UB96@1239|Firmicutes,4IMMY@91061|Bacilli,1ZKG6@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5030122_1	574375.BAGA_06540	5.613e-90	300.0	2CA96@1|root,2ZBTW@2|Bacteria,1V2TR@1239|Firmicutes,4HGFJ@91061|Bacilli,1ZC8Q@1386|Bacillus	91061|Bacilli	S	Cell division protein FtsN	tasA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06336	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M73
HKD3_k127_5030122_2	1169144.KB910949_gene3557	2.878e-52	190.0	COG0681@1|root,COG0681@2|Bacteria,1V2HE@1239|Firmicutes,4HFVV@91061|Bacilli,1ZFV9@1386|Bacillus	91061|Bacilli	U	Signal peptidase	sipW	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD3_k127_5030122_4	1405.DJ92_3925	4.67e-09	66.0	COG3064@1|root,COG3064@2|Bacteria,1UBER@1239|Firmicutes,4IMTC@91061|Bacilli,1ZKSY@1386|Bacillus	91061|Bacilli	M	Domain of unknown function (DUF4047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4047
HKD3_k127_5030122_0	1169144.KB910949_gene3556	7.247e-145	469.0	COG1686@1|root,COG1686@2|Bacteria,1V29Q@1239|Firmicutes,4HFS3@91061|Bacilli,1ZMFV@1386|Bacillus	91061|Bacilli	M	Penicillin-binding protein 5, C-terminal domain	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	PBP5_C,Peptidase_S11
HKD3_k127_5030122_3	315749.Bcer98_0993	2.689e-43	160.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4I3DX@91061|Bacilli,1ZJFH@1386|Bacillus	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD3_k127_5067857_4	1444310.JANV01000064_gene1969	0.0002243	51.0	2BA87@1|root,323NA@2|Bacteria,1V54Z@1239|Firmicutes,4HGZH@91061|Bacilli,1ZIG0@1386|Bacillus	91061|Bacilli	-	-	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,PilO
HKD3_k127_5067857_3	1174504.AJTN02000248_gene3775	1.683e-16	87.0	COG3166@1|root,COG3166@2|Bacteria,1VBC6@1239|Firmicutes,4HMG7@91061|Bacilli,1ZI0A@1386|Bacillus	91061|Bacilli	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
HKD3_k127_5067857_1	796606.BMMGA3_12580	9.574e-69	244.0	COG4972@1|root,COG4972@2|Bacteria,1TSTG@1239|Firmicutes,4HFQU@91061|Bacilli,1ZC5N@1386|Bacillus	91061|Bacilli	NU	COG4972 Tfp pilus assembly protein, ATPase PilM	-	-	-	ko:K02662,ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
HKD3_k127_5067857_0	796606.BMMGA3_12585	7.806e-85	287.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli,1ZCQ2@1386|Bacillus	91061|Bacilli	NOU	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases	comC	-	3.4.23.43	ko:K02236,ko:K02654	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HKD3_k127_5067857_2	796606.BMMGA3_12590	1.856e-26	112.0	COG4969@1|root,COG4969@2|Bacteria,1UI23@1239|Firmicutes,4HNRA@91061|Bacilli,1ZIV6@1386|Bacillus	91061|Bacilli	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
HKD3_k127_5070551_1	1169144.KB910949_gene3541	2.094e-197	622.0	COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZS14@1386|Bacillus	91061|Bacilli	E	COG1113 Gamma-aminobutyrate permease and related permeases	yvbW	-	-	ko:K03293	-	-	-	-	ko00000	2.A.3.1	-	-	AA_permease
HKD3_k127_5070551_3	574375.BAGA_26135	1.36e-147	473.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HD0H@91061|Bacilli,1ZASN@1386|Bacillus	91061|Bacilli	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS10595	PfkB
HKD3_k127_5070551_0	574375.BAGA_26130	9.566e-226	710.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZCBA@1386|Bacillus	91061|Bacilli	G	invertase	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
HKD3_k127_5070551_2	574375.BAGA_26125	4.681e-196	616.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus	91061|Bacilli	G	phosphotransferase system	scrA	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HKD3_k127_5095285_1	1405.DJ92_1061	2.801e-59	207.0	2AN64@1|root,31D41@2|Bacteria,1V7Z3@1239|Firmicutes,4HJDV@91061|Bacilli,1ZFW5@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1885
HKD3_k127_5095285_0	1169144.KB910924_gene531	3.586e-207	648.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	pdhD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD3_k127_5101828_13	1121091.AUMP01000001_gene534	5.47e-15	75.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
HKD3_k127_5101828_4	1131730.BAVI_24238	1.726e-82	282.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HF93@91061|Bacilli,1ZFXE@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	pdaC	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HKD3_k127_5101828_0	1395587.P364_0130880	9.712e-120	391.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,26QPC@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	yeaB	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD3_k127_5101828_1	1157490.EL26_17640	2.589e-108	358.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,279AK@186823|Alicyclobacillaceae	91061|Bacilli	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	ydfM	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD3_k127_5101828_7	666686.B1NLA3E_12235	1.693e-62	219.0	COG1595@1|root,COG1595@2|Bacteria,1V94Z@1239|Firmicutes,4HJG5@91061|Bacilli,1ZHW8@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_5101828_9	666686.B1NLA3E_12225	1.042e-49	187.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HKD3_k127_5101828_3	1243664.CAVL020000058_gene4413	1.008e-89	299.0	COG0586@1|root,COG0586@2|Bacteria,1V1D4@1239|Firmicutes,4HFSU@91061|Bacilli,1ZCPB@1386|Bacillus	91061|Bacilli	S	membrane-associated protein	yngC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD3_k127_5101828_6	315730.BcerKBAB4_2489	3.884e-68	237.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HN1F@91061|Bacilli,1ZHT2@1386|Bacillus	91061|Bacilli	I	Acid phosphatase homologues	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_5101828_10	649747.HMPREF0083_02135	1.682e-49	184.0	COG0398@1|root,COG0398@2|Bacteria,1V5JT@1239|Firmicutes,4HH3C@91061|Bacilli,26V67@186822|Paenibacillaceae	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD3_k127_5101828_2	1340434.AXVA01000003_gene2519	1.363e-107	360.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HBCD@91061|Bacilli,1ZQUR@1386|Bacillus	91061|Bacilli	M	Monogalactosyldiacylglycerol (MGDG) synthase	ugtP5	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD3_k127_5101828_5	649747.HMPREF0083_03221	3.171e-74	256.0	COG0726@1|root,COG0726@2|Bacteria,1TPWK@1239|Firmicutes,4HEQ2@91061|Bacilli,26R03@186822|Paenibacillaceae	91061|Bacilli	G	deacetylase	cda2	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_5101828_8	471223.GWCH70_0558	1.73e-53	194.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,4HGJC@91061|Bacilli,1WG26@129337|Geobacillus	91061|Bacilli	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HKD3_k127_5101828_12	1120973.AQXL01000117_gene388	1.997e-15	78.0	COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	csoR_1	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
HKD3_k127_5101828_11	279010.BL02055	1.947e-19	88.0	COG0730@1|root,COG0730@2|Bacteria,1TRIE@1239|Firmicutes,4HARW@91061|Bacilli,1ZC6G@1386|Bacillus	91061|Bacilli	S	membrane transporter protein	yrkJ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_5109190_1	1405.DJ92_1854	5.001e-106	349.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,1ZD6V@1386|Bacillus	91061|Bacilli	M	Glycosyl Transferase	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_5109190_0	1341151.ASZU01000012_gene1699	6.398e-220	689.0	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,27DBF@186824|Thermoactinomycetaceae	91061|Bacilli	EGP	Sugar (and other) transporter	mdr	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_5115287_0	1403313.AXBR01000002_gene4110	7.505e-133	426.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,1ZAXT@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_5115287_1	698769.JFBD01000136_gene97	3.904e-11	65.0	2DQAQ@1|root,335PA@2|Bacteria,1VHG5@1239|Firmicutes,4IC1G@91061|Bacilli,4C62X@84406|Virgibacillus	91061|Bacilli	S	Small, acid-soluble spore protein, gamma-type	-	-	-	ko:K06422	-	-	-	-	ko00000	-	-	-	SASP_gamma
HKD3_k127_5122797_2	1169144.KB910965_gene3043	2.778e-07	52.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,1ZIUG@1386|Bacillus	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HKD3_k127_5122797_1	1169144.KB910965_gene3042	1.768e-118	384.0	COG0805@1|root,COG0805@2|Bacteria,1V372@1239|Firmicutes,4HFT0@91061|Bacilli,1ZQXF@1386|Bacillus	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_5122797_0	1169144.KB910965_gene3041	1.17e-141	451.0	COG1740@1|root,COG1740@2|Bacteria,1TZZD@1239|Firmicutes,4HAJX@91061|Bacilli,1ZDQD@1386|Bacillus	91061|Bacilli	C	COG1740 Ni,Fe-hydrogenase I small subunit	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
HKD3_k127_5133686_0	1034347.CAHJ01000040_gene4394	7.17e-242	752.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
HKD3_k127_5133686_2	315749.Bcer98_3178	2.378e-176	556.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,1ZARK@1386|Bacillus	91061|Bacilli	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HKD3_k127_5133686_6	260799.BAS4360	1.445e-78	270.0	COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1ZGER@1386|Bacillus	91061|Bacilli	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD3_k127_5133686_3	1169144.KB910928_gene1894	2.801e-147	471.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,1ZCR0@1386|Bacillus	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
HKD3_k127_5133686_4	1405.DJ92_1562	3.66e-130	420.0	COG0755@1|root,COG0755@2|Bacteria,1U8IP@1239|Firmicutes,4HD6H@91061|Bacilli,1ZBFP@1386|Bacillus	91061|Bacilli	O	cytochrome C	hemX	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	ko:K02497	-	-	-	-	ko00000	-	-	-	Cytochrom_C_asm
HKD3_k127_5133686_1	315749.Bcer98_3182	1.197e-214	673.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08420	GlutR_N,GlutR_dimer,Shikimate_DH
HKD3_k127_5133686_5	315749.Bcer98_3183	1.152e-86	288.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,1ZBX7@1386|Bacillus	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD3_k127_5139646_2	1211814.CAPG01000003_gene89	1.937e-229	713.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,1ZB0F@1386|Bacillus	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HKD3_k127_5139646_1	666686.B1NLA3E_07505	6.478e-246	764.0	COG2271@1|root,COG2271@2|Bacteria,1TP6X@1239|Firmicutes,4IQRT@91061|Bacilli	91061|Bacilli	G	Major facilitator superfamily	exuT	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
HKD3_k127_5139646_4	666686.B1NLA3E_07560	7.708e-97	318.0	2DMKN@1|root,32S7N@2|Bacteria,1UBGT@1239|Firmicutes,4IMVR@91061|Bacilli,1ZKY8@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5139646_0	666686.B1NLA3E_07555	7.218e-249	769.0	COG1960@1|root,COG1960@2|Bacteria,1UW6I@1239|Firmicutes,4IMZ5@91061|Bacilli,1ZMA2@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_5139646_3	666686.B1NLA3E_07500	1.284e-118	391.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4IMW1@91061|Bacilli,1ZKZ3@1386|Bacillus	91061|Bacilli	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_5184060_1	717605.Theco_0082	1.436e-205	647.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,26QM0@186822|Paenibacillaceae	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
HKD3_k127_5184060_7	997296.PB1_11184	8.595e-70	238.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HIEM@91061|Bacilli,1ZQR8@1386|Bacillus	91061|Bacilli	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
HKD3_k127_5184060_9	315749.Bcer98_1479	2.976e-50	190.0	COG2207@1|root,COG2207@2|Bacteria,1V1JH@1239|Firmicutes,4IR2Y@91061|Bacilli,1ZGA4@1386|Bacillus	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD3_k127_5184060_0	44251.PDUR_11695	6.199e-309	960.0	COG3733@1|root,COG3733@2|Bacteria,1VRW1@1239|Firmicutes,4HURV@91061|Bacilli,26W22@186822|Paenibacillaceae	91061|Bacilli	Q	amine oxidase	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
HKD3_k127_5184060_11	1121091.AUMP01000066_gene3487	3.201e-05	52.0	COG4454@1|root,COG4454@2|Bacteria,1V23W@1239|Firmicutes,4HGGT@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
HKD3_k127_5184060_4	1089439.KB902252_gene1438	2.826e-134	443.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,463IC@72273|Thiotrichales	72273|Thiotrichales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD3_k127_5184060_8	471223.GWCH70_2051	8.518e-62	220.0	29H6Z@1|root,3044I@2|Bacteria,1V4SZ@1239|Firmicutes,4HHCE@91061|Bacilli,1WFCJ@129337|Geobacillus	91061|Bacilli	-	-	ywrJ	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5184060_2	1169144.KB910979_gene1555	7.949e-196	620.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus	91061|Bacilli	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
HKD3_k127_5184060_5	504472.Slin_4020	5.122e-95	321.0	COG0657@1|root,COG0657@2|Bacteria,4NIQ0@976|Bacteroidetes,47JK6@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HKD3_k127_5184060_10	1196031.ALEG01000068_gene4845	4.855e-37	141.0	COG2197@1|root,COG2197@2|Bacteria,1VBZR@1239|Firmicutes,4HKT4@91061|Bacilli,1ZHTA@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	gerE	-	-	ko:K01994	-	-	-	-	ko00000,ko03000	-	-	-	GerE
HKD3_k127_5184060_3	574375.BAGA_03975	1.792e-137	443.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,1ZBC9@1386|Bacillus	91061|Bacilli	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU28390	Asp_Glu_race
HKD3_k127_5184060_6	574375.BAGA_03970	5.971e-93	310.0	COG5401@1|root,COG5401@2|Bacteria,1TPQD@1239|Firmicutes,4HB1S@91061|Bacilli,1ZBZJ@1386|Bacillus	91061|Bacilli	S	COG5401 Spore germination protein	gerM	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
HKD3_k127_5193717_1	315730.BcerKBAB4_4219	3.746e-81	272.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus	91061|Bacilli	E	cystathionine	mccB	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27250	Cys_Met_Meta_PP
HKD3_k127_5193717_5	1169144.KB910936_gene1289	1.741e-15	78.0	2A1KA@1|root,30PU9@2|Bacteria,1UB4E@1239|Firmicutes,4IMH0@91061|Bacilli,1ZK4Y@1386|Bacillus	91061|Bacilli	S	YrhC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YrhC
HKD3_k127_5193717_4	1280390.CBQR020000167_gene4453	2.577e-24	109.0	2E5TW@1|root,330I6@2|Bacteria,1VIUC@1239|Firmicutes,4HQUN@91061|Bacilli,26YZP@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5193717_3	1347369.CCAD010000094_gene2231	7.559e-54	194.0	COG1695@1|root,COG1695@2|Bacteria,1V7AI@1239|Firmicutes,4HISS@91061|Bacilli,1ZFMT@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
HKD3_k127_5193717_0	1340434.AXVA01000020_gene1422	1.97e-85	289.0	COG1651@1|root,COG1651@2|Bacteria,1V6IC@1239|Firmicutes,4HIBC@91061|Bacilli,1ZR7I@1386|Bacillus	91061|Bacilli	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HKD3_k127_5193717_2	586416.GZ22_00780	2.111e-54	193.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
HKD3_k127_5209652_1	198094.BA_4053	1.969e-234	733.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_5209652_7	634956.Geoth_2799	1.23e-156	499.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,1WEB0@129337|Geobacillus	91061|Bacilli	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HKD3_k127_5209652_2	1169144.KB910924_gene478	1.705e-218	684.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD3_k127_5209652_5	1169144.KB910924_gene477	1.091e-194	612.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBY5@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD3_k127_5209652_8	1169144.KB910924_gene475	1.87e-147	472.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,1ZC3F@1386|Bacillus	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
HKD3_k127_5209652_14	1169144.KB910924_gene474	7.85e-80	274.0	COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,1ZDSW@1386|Bacillus	91061|Bacilli	D	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex	divIB	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
HKD3_k127_5209652_20	279010.BL02249	0.0004827	43.0	COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,4HIMZ@91061|Bacilli,1ZGAQ@1386|Bacillus	91061|Bacilli	S	small basic protein	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
HKD3_k127_5209652_3	574376.BAMA_08900	6.24e-203	638.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus	91061|Bacilli	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	DUF3484,FtsA,SHS2_FTSA
HKD3_k127_5209652_4	574376.BAMA_08895	2.171e-201	631.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HKD3_k127_5209652_11	1169144.KB910924_gene471	8.686e-100	334.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,4HDX6@91061|Bacilli,1ZAV2@1386|Bacillus	91061|Bacilli	M	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR	spoIIGA	GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
HKD3_k127_5209652_9	1169144.KB910924_gene470	1.857e-134	430.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,4H9PG@91061|Bacilli,1ZBKD@1386|Bacillus	91061|Bacilli	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD3_k127_5209652_6	260799.BAS3754	3.384e-164	518.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,4H9MN@91061|Bacilli,1ZB53@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_5209652_17	1169144.KB910924_gene467	5.323e-32	128.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,4HNT3@91061|Bacilli,1ZI0Y@1386|Bacillus	91061|Bacilli	S	sporulation protein	ylmC	-	-	-	-	-	-	-	-	-	-	-	PRC
HKD3_k127_5209652_10	1169144.KB910924_gene466	3.63e-118	385.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,1ZBZZ@1386|Bacillus	91061|Bacilli	S	Belongs to the multicopper oxidase YfiH RL5 family	ylmD	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HKD3_k127_5209652_13	574375.BAGA_00915	8.486e-91	303.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,1ZARM@1386|Bacillus	91061|Bacilli	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD3_k127_5209652_16	1169144.KB910924_gene464	1.172e-61	215.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,1ZGE0@1386|Bacillus	91061|Bacilli	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HKD3_k127_5209652_18	796606.BMMGA3_05745	4.369e-27	112.0	COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,1ZHUZ@1386|Bacillus	91061|Bacilli	S	membrane	ylmG	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
HKD3_k127_5209652_12	1405.DJ92_988	9.691e-99	328.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,1ZC97@1386|Bacillus	91061|Bacilli	S	conserved protein, contains S4-like domain	ylmH	-	-	-	-	-	-	-	-	-	-	-	S4
HKD3_k127_5209652_15	1169144.KB910924_gene461	9.385e-80	269.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,1ZFNB@1386|Bacillus	91061|Bacilli	D	Cell division initiation protein	divIVA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
HKD3_k127_5209652_0	315749.Bcer98_2544	0.0	1664.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus	91061|Bacilli	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
HKD3_k127_5209652_19	574376.BAMA_08835	4.4e-24	106.0	COG1734@1|root,COG1734@2|Bacteria,1UAPS@1239|Firmicutes,4IM2E@91061|Bacilli,1ZIVI@1386|Bacillus	91061|Bacilli	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5223717_0	574376.BAMA_08350	1.254e-216	681.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD3_k127_5223717_3	315730.BcerKBAB4_3568	5.241e-141	452.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD3_k127_5223717_1	574376.BAMA_08360	6.327e-204	640.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZBSQ@1386|Bacillus	91061|Bacilli	E	Belongs to the aspartokinase family	dapG	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
HKD3_k127_5223717_2	1169144.KB910924_gene316	5.852e-191	600.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,1ZAVS@1386|Bacillus	91061|Bacilli	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_5223717_6	1396.DJ87_1130	1.33e-25	106.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,4HAU9@91061|Bacilli,1ZCJQ@1386|Bacillus	91061|Bacilli	H	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	iYO844.BSU16740	Flavoprotein
HKD3_k127_5223717_5	574376.BAMA_20875	6.936e-88	293.0	COG1279@1|root,COG1279@2|Bacteria,1V1Q2@1239|Firmicutes,4HFYS@91061|Bacilli,1ZFM6@1386|Bacillus	91061|Bacilli	S	Lysine exporter protein LysE YggA	argO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
HKD3_k127_5223717_9	198094.BA_3289	1.09e-07	57.0	2EAKH@1|root,334P5@2|Bacteria,1VMKG@1239|Firmicutes,4HNTF@91061|Bacilli,1ZIRN@1386|Bacillus	91061|Bacilli	S	YolD-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YolD
HKD3_k127_5223717_4	198094.BA_3288	8.862e-125	413.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,1ZC8I@1386|Bacillus	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	polYB	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD3_k127_5223717_7	1123252.ATZF01000006_gene792	3.485e-20	93.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HCQ7@91061|Bacilli,27DAG@186824|Thermoactinomycetaceae	91061|Bacilli	L	Recombinase zinc beta ribbon domain	XK27_10845	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HKD3_k127_5248860_1	1169144.KB910924_gene363	8.138e-129	423.0	COG1961@1|root,COG1961@2|Bacteria,1TP0S@1239|Firmicutes,4HBBX@91061|Bacilli,1ZD0E@1386|Bacillus	91061|Bacilli	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HKD3_k127_5248860_2	574376.BAMA_08370	4.311e-74	251.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,4HAU9@91061|Bacilli,1ZCJQ@1386|Bacillus	91061|Bacilli	H	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	iYO844.BSU16740	Flavoprotein
HKD3_k127_5248860_0	574376.BAMA_08375	7.103e-151	481.0	COG0169@1|root,COG0169@2|Bacteria,1UHR5@1239|Firmicutes,4IS6W@91061|Bacilli,1ZS11@1386|Bacillus	91061|Bacilli	E	subunit a	spoVFA	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N
HKD3_k127_5277519_19	574376.BAMA_13670	1.181e-20	95.0	2B02J@1|root,31SCS@2|Bacteria,1V9YF@1239|Firmicutes,4HKUD@91061|Bacilli	91061|Bacilli	-	-	liaI	-	-	ko:K11619	ko02020,map02020	M00754	-	-	ko00000,ko00001,ko00002	-	-	-	-
HKD3_k127_5277519_10	315749.Bcer98_1157	1.232e-73	253.0	COG1842@1|root,COG1842@2|Bacteria,1TRQ4@1239|Firmicutes,4HG75@91061|Bacilli,1ZQKT@1386|Bacillus	91061|Bacilli	KT	PspA/IM30 family	-	-	-	-	-	-	-	-	-	-	-	-	PspA_IM30
HKD3_k127_5277519_9	574375.BAGA_06995	7.068e-78	267.0	COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,1ZDPB@1386|Bacillus	91061|Bacilli	S	Cell wall-active antibiotics response 4TMS YvqF	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
HKD3_k127_5277519_3	574375.BAGA_07000	4.417e-132	429.0	COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus	91061|Bacilli	T	Histidine kinase	vraS	-	2.7.13.3	ko:K07681,ko:K11617	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
HKD3_k127_5277519_6	574376.BAMA_13690	1.394e-106	348.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,1ZAT4@1386|Bacillus	91061|Bacilli	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
HKD3_k127_5277519_16	935836.JAEL01000017_gene795	1.672e-35	139.0	2C860@1|root,32RKH@2|Bacteria,1VATE@1239|Firmicutes,4HMZP@91061|Bacilli,1ZHVD@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5277519_22	1169144.KB910929_gene1832	6.484e-15	77.0	29RS2@1|root,30CVS@2|Bacteria,1UAFT@1239|Firmicutes,4IKU6@91061|Bacilli,1ZNJ7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5277519_13	574375.BAGA_07050	2.069e-49	181.0	2DJ1F@1|root,32UC4@2|Bacteria,1VB5Z@1239|Firmicutes,4HMEG@91061|Bacilli,1ZJ8V@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5277519_8	260799.BAS1358	1.035e-82	277.0	COG0664@1|root,COG0664@2|Bacteria,1VV51@1239|Firmicutes,4HVPD@91061|Bacilli,1ZGHF@1386|Bacillus	91061|Bacilli	T	Crp fnr family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD3_k127_5277519_18	574375.BAGA_07065	1.987e-28	115.0	29SSA@1|root,30DY8@2|Bacteria,1UBW3@1239|Firmicutes,4INBP@91061|Bacilli,1ZN75@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5277519_2	1211814.CAPG01000032_gene1491	1.265e-149	479.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,1ZBFE@1386|Bacillus	91061|Bacilli	P	phosphate transporter	pit	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD3_k127_5277519_12	574376.BAMA_13755	3.453e-68	239.0	COG1392@1|root,COG1392@2|Bacteria,1UYRI@1239|Firmicutes,4HC4X@91061|Bacilli,1ZCU7@1386|Bacillus	91061|Bacilli	P	Protein of unknown function DUF47	ykaA	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HKD3_k127_5277519_4	1169144.KB910929_gene1817	7.696e-130	421.0	COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,1ZATP@1386|Bacillus	91061|Bacilli	S	Protein of unknown function DUF72	yunF	-	-	-	-	-	-	-	-	-	-	-	DUF72
HKD3_k127_5277519_21	1169144.KB910929_gene1814	2.025e-17	83.0	29QTZ@1|root,30BTZ@2|Bacteria,1U8NR@1239|Firmicutes,4IIKP@91061|Bacilli,1ZNRM@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3924
HKD3_k127_5277519_7	574375.BAGA_07115	7.432e-86	287.0	COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4HG5J@91061|Bacilli,1ZFS4@1386|Bacillus	91061|Bacilli	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD3_k127_5277519_1	1405.DJ92_4110	1.94e-235	745.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HD2Y@91061|Bacilli,1ZBYX@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K18345	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HKD3_k127_5277519_5	1169144.KB910929_gene1811	1.551e-127	410.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,1ZCBV@1386|Bacillus	91061|Bacilli	F	Purine nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_5277519_0	1169144.KB910929_gene1809	9.116e-321	1002.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,1ZCB5@1386|Bacillus	91061|Bacilli	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
HKD3_k127_5277519_15	666686.B1NLA3E_15070	8.417e-41	154.0	2A9NA@1|root,30YV1@2|Bacteria,1V47Y@1239|Firmicutes,4HIDD@91061|Bacilli,1ZGBG@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5277519_11	315749.Bcer98_1191	4.765e-71	243.0	29P42@1|root,30A29@2|Bacteria,1V423@1239|Firmicutes,4HH8N@91061|Bacilli,1ZG69@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3907)	ypuI	-	-	-	-	-	-	-	-	-	-	-	DUF3907
HKD3_k127_528861_8	1347086.CCBA010000024_gene3031	1.917e-63	220.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HAY0@91061|Bacilli,1ZF66@1386|Bacillus	91061|Bacilli	GM	GDP-mannose 4,6 dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_528861_5	1501230.ET33_31240	1.356e-87	294.0	COG4122@1|root,COG4122@2|Bacteria,1VS6G@1239|Firmicutes,4HTS1@91061|Bacilli,271Z0@186822|Paenibacillaceae	91061|Bacilli	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_528861_6	1385513.N780_17740	1.539e-75	262.0	COG1442@1|root,COG1442@2|Bacteria,1V2FM@1239|Firmicutes,4HJHP@91061|Bacilli	91061|Bacilli	M	Glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
HKD3_k127_528861_4	1501230.ET33_31225	4.387e-88	301.0	COG1216@1|root,COG1216@2|Bacteria,1VH9I@1239|Firmicutes,4ISDM@91061|Bacilli,27725@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_528861_7	1173027.Mic7113_3610	2.161e-70	252.0	COG4421@1|root,COG4421@2|Bacteria,1G22H@1117|Cyanobacteria,1H8WY@1150|Oscillatoriales	1117|Cyanobacteria	G	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,TPR_1
HKD3_k127_528861_1	457570.Nther_1573	2.976e-126	413.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_528861_10	1396.DJ87_4010	0.0008264	43.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ywqF	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD3_k127_528861_3	1385513.N780_17760	4.348e-92	309.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,2YA2B@289201|Pontibacillus	91061|Bacilli	M	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD3_k127_528861_0	1405.DJ92_3821	1.07e-136	437.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus	91061|Bacilli	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_528861_2	1169144.KB910927_gene1321	2.446e-119	387.0	COG0639@1|root,COG0639@2|Bacteria,1TPCI@1239|Firmicutes,4HBD8@91061|Bacilli,1ZBK8@1386|Bacillus	91061|Bacilli	T	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP	prpE	GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.16,3.6.1.41	ko:K01090,ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD3_k127_528861_9	574375.BAGA_21185	1.192e-30	122.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD3_k127_5289106_0	1444310.JANV01000185_gene451	5.65e-142	458.0	COG4638@1|root,COG4638@2|Bacteria,1UZWG@1239|Firmicutes,4HBGQ@91061|Bacilli,1ZMEW@1386|Bacillus	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
HKD3_k127_5289106_2	1034347.CAHJ01000045_gene517	5.232e-54	196.0	COG3195@1|root,COG3195@2|Bacteria,1VB2S@1239|Firmicutes,4HM1Y@91061|Bacilli,1ZR64@1386|Bacillus	91061|Bacilli	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K13485	ko00230,ko01100,map00230,map01100	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
HKD3_k127_5289106_1	224308.BSU32450	2.64e-136	440.0	COG3195@1|root,COG3648@1|root,COG3195@2|Bacteria,COG3648@2|Bacteria,1UY6S@1239|Firmicutes,4HAQX@91061|Bacilli,1ZCAY@1386|Bacillus	91061|Bacilli	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	-	-	1.7.3.3,4.1.1.97	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R06604,R07981	RC01551,RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox,Uricase
HKD3_k127_5289106_3	1028801.RG1141_CH26600	1.054e-40	153.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,2U9IT@28211|Alphaproteobacteria,4BERF@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
HKD3_k127_5289106_4	1078085.HMPREF1210_02241	4.206e-26	109.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4IA3I@91061|Bacilli,26HMG@186818|Planococcaceae	91061|Bacilli	S	TQO small subunit DoxD	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD3_k127_5290590_1	574376.BAMA_06390	3.512e-149	488.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,1ZAP5@1386|Bacillus	91061|Bacilli	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
HKD3_k127_5290590_0	1169144.KB910934_gene4262	1.358e-188	595.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,1ZBQQ@1386|Bacillus	91061|Bacilli	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HKD3_k127_5290590_4	315749.Bcer98_1734	3.115e-24	104.0	2EA0D@1|root,3345V@2|Bacteria,1VES6@1239|Firmicutes,4HNHV@91061|Bacilli,1ZHVU@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2584)	ytmB	-	-	-	-	-	-	-	-	-	-	-	DUF2584
HKD3_k127_5290590_5	1408303.JNJJ01000002_gene3896	4.088e-18	90.0	2EDI2@1|root,337E0@2|Bacteria,1VGWT@1239|Firmicutes,4HP0C@91061|Bacilli,1ZJ3Z@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5290590_3	574376.BAMA_06245	1.103e-47	173.0	COG0526@1|root,COG0526@2|Bacteria,1VA84@1239|Firmicutes,4HKCD@91061|Bacilli,1ZHXM@1386|Bacillus	91061|Bacilli	CO	Thioredoxin	ydbP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD3_k127_5290590_2	1405.DJ92_4862	3.237e-63	224.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZIEP@1386|Bacillus	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	yodM	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_5297496_0	315749.Bcer98_0431	3.459e-207	649.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli,1ZBEP@1386|Bacillus	91061|Bacilli	C	formate acetyltransferase	pflB	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HKD3_k127_5297496_3	1405.DJ92_4417	7.15e-27	124.0	COG3757@1|root,COG3757@2|Bacteria,1V998@1239|Firmicutes,4HMWC@91061|Bacilli,1ZH8N@1386|Bacillus	91061|Bacilli	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glyco_hydro_25,LysM
HKD3_k127_5297496_2	1122921.KB898187_gene4345	2.822e-71	256.0	COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1UYW5@1239|Firmicutes,4HF0Y@91061|Bacilli,2749Y@186822|Paenibacillaceae	91061|Bacilli	M	Ami_2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2,CHAP,PG_binding_1
HKD3_k127_5297496_1	315749.Bcer98_3282	4.258e-200	632.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HKD3_k127_5361308_13	574375.BAGA_00415	3.27e-25	108.0	COG1873@1|root,COG1873@2|Bacteria,1VEJW@1239|Firmicutes,4HPFQ@91061|Bacilli,1ZI6Z@1386|Bacillus	91061|Bacilli	S	YlmC YmxH family	ymxH	-	-	-	-	-	-	-	-	-	-	-	PRC
HKD3_k127_5361308_2	574376.BAMA_08380	4.831e-224	699.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli,1ZDJE@1386|Bacillus	91061|Bacilli	S	Belongs to the peptidase M16 family	mlpA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_5361308_7	315749.Bcer98_2458	7.503e-128	416.0	COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,4HAHC@91061|Bacilli,1ZC6V@1386|Bacillus	91061|Bacilli	G	Sporulation protein, polysaccharide deacetylase	ylxY	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_5361308_0	315730.BcerKBAB4_3629	0.0	1173.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD3_k127_5361308_11	198094.BA_3945	2.438e-44	163.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,1ZH7M@1386|Bacillus	91061|Bacilli	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD3_k127_5361308_5	574376.BAMA_08400	8.253e-147	470.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,1ZBFH@1386|Bacillus	91061|Bacilli	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06310	FAD_syn,Flavokinase
HKD3_k127_5361308_6	574376.BAMA_08405	3.524e-142	456.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
HKD3_k127_5361308_9	315730.BcerKBAB4_3633	3.21e-61	213.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,1ZGB3@1386|Bacillus	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD3_k127_5361308_1	574375.BAGA_00460	0.0	1092.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HKD3_k127_5361308_10	1405.DJ92_900	6.263e-48	173.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,1ZI1N@1386|Bacillus	91061|Bacilli	J	ribosomal protein	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
HKD3_k127_5361308_12	315749.Bcer98_2467	5.809e-34	132.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,1ZHSV@1386|Bacillus	91061|Bacilli	K	nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
HKD3_k127_5361308_3	574375.BAGA_00475	4.451e-202	632.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus	91061|Bacilli	K	Participates in both transcription termination and antitermination	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HKD3_k127_5361308_8	315749.Bcer98_2469	5.316e-77	260.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,1ZG6S@1386|Bacillus	91061|Bacilli	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HKD3_k127_5361308_4	1169144.KB910924_gene380	8.563e-187	586.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus	91061|Bacilli	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD3_k127_5380420_4	666686.B1NLA3E_08280	3.412e-73	248.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,4HK76@91061|Bacilli,1ZQDT@1386|Bacillus	91061|Bacilli	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HKD3_k127_5380420_1	545693.BMQ_3506	7.303e-143	461.0	COG4335@1|root,COG4335@2|Bacteria,1TRE4@1239|Firmicutes,4HA0G@91061|Bacilli,1ZBAW@1386|Bacillus	91061|Bacilli	L	DNA alkylation repair enzyme	yhaZ	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HKD3_k127_5380420_5	1294142.CINTURNW_2561	4.727e-48	176.0	COG0295@1|root,COG0295@2|Bacteria,1V82B@1239|Firmicutes,24NJA@186801|Clostridia,36MR1@31979|Clostridiaceae	186801|Clostridia	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD3_k127_5380420_2	358681.BBR47_29990	1.551e-106	350.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,26TNF@186822|Paenibacillaceae	91061|Bacilli	C	NAD(P)H-dependent oxidoreductase	nfrA	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
HKD3_k127_5380420_7	1280390.CBQR020000049_gene992	2.434e-37	145.0	COG1633@1|root,COG1633@2|Bacteria,1V7ZC@1239|Firmicutes,4HIIC@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF2383)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	DUF2383
HKD3_k127_5380420_0	1234664.AMRO01000023_gene1726	6.263e-207	653.0	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1WEG9@129337|Geobacillus	91061|Bacilli	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD3_k127_5380420_6	1231057.AMGD01000059_gene1232	6.336e-46	171.0	28NEG@1|root,30K8K@2|Bacteria,1UWMF@1239|Firmicutes,4IJSA@91061|Bacilli,26I3D@186818|Planococcaceae	91061|Bacilli	S	Staygreen protein	-	-	-	-	-	-	-	-	-	-	-	-	Staygreen
HKD3_k127_5380420_3	1169144.KB910955_gene224	2.38e-92	306.0	2CEJD@1|root,2Z81V@2|Bacteria,1UD9R@1239|Firmicutes,4HAPP@91061|Bacilli,1ZC32@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3900)	yetN	-	-	-	-	-	-	-	-	-	-	-	DUF3898,DUF3900
HKD3_k127_5387511_1	1169144.KB910956_gene4103	1.941e-11	66.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus	91061|Bacilli	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD3_k127_5387511_0	1051501.AYTL01000009_gene211	2.755e-156	497.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZBC7@1386|Bacillus	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD3_k127_5387511_2	1396.DJ87_5564	2.032e-11	64.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,1ZBFC@1386|Bacillus	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
HKD3_k127_5392084_4	315730.BcerKBAB4_5163	1.066e-146	466.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HA7S@91061|Bacilli,1ZB9A@1386|Bacillus	91061|Bacilli	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD3_k127_5392084_8	1536769.P40081_19895	1.148e-120	392.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HBW9@91061|Bacilli,26SY7@186822|Paenibacillaceae	91061|Bacilli	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HKD3_k127_5392084_2	1499689.CCNN01000007_gene1899	2.722e-183	584.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia,36DXR@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
HKD3_k127_5392084_9	545243.BAEV01000121_gene3067	8.159e-112	366.0	COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,24AZD@186801|Clostridia,36FB4@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
HKD3_k127_5392084_10	1499689.CCNN01000007_gene1901	4.609e-102	340.0	COG1175@1|root,COG1175@2|Bacteria,1TSIQ@1239|Firmicutes,25C4Z@186801|Clostridia,36DJN@31979|Clostridiaceae	186801|Clostridia	G	inner membrane component	-	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
HKD3_k127_5392084_12	574376.BAMA_01650	2.314e-99	329.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,1ZAVP@1386|Bacillus	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
HKD3_k127_5392084_0	1169144.KB910926_gene1188	4.053e-287	895.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	pbpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_5392084_14	1169144.KB910926_gene1186	5.97e-81	272.0	28J0N@1|root,2Z8XT@2|Bacteria,1V1UK@1239|Firmicutes,4HD4W@91061|Bacilli,1ZBQ1@1386|Bacillus	91061|Bacilli	S	YwhD family	ywhD	-	-	-	-	-	-	-	-	-	-	-	YwhD
HKD3_k127_5392084_11	1405.DJ92_2464	8.337e-102	335.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H9SF@91061|Bacilli,1ZCSE@1386|Bacillus	91061|Bacilli	S	Peptidase M50	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HKD3_k127_5392084_20	491915.Aflv_2754	9.232e-28	113.0	COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,21VVE@150247|Anoxybacillus	91061|Bacilli	G	Tautomerase enzyme	dmpI	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
HKD3_k127_5392084_1	1169144.KB910926_gene1183	3.018e-247	767.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus	91061|Bacilli	S	COG1078 HD superfamily phosphohydrolases	ywfO	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
HKD3_k127_5392084_19	997296.PB1_07852	3.962e-35	134.0	COG4844@1|root,COG4844@2|Bacteria,1VB5Q@1239|Firmicutes,4HKJX@91061|Bacilli,1ZHXV@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0741 family	ywzC	-	-	-	-	-	-	-	-	-	-	-	DUF1450
HKD3_k127_5392084_13	1169144.KB910926_gene1177	1.201e-90	304.0	2C8MW@1|root,305IT@2|Bacteria,1V5HI@1239|Firmicutes,4HI2B@91061|Bacilli,1ZQRC@1386|Bacillus	91061|Bacilli	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	rsfA	-	-	ko:K06314	-	-	-	-	ko00000,ko03000	-	-	-	Myb_DNA-bind_6
HKD3_k127_5392084_6	1461580.CCAS010000016_gene1987	1.301e-138	447.0	COG2042@1|root,COG3376@2|Bacteria,1U4YZ@1239|Firmicutes,4IEY4@91061|Bacilli,1ZKA1@1386|Bacillus	91061|Bacilli	U	High-affinity nickel-transport protein	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
HKD3_k127_5392084_7	574375.BAGA_13170	6.406e-121	393.0	COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,1ZCIA@1386|Bacillus	91061|Bacilli	H	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes	lipL	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.200,2.3.1.204	ko:K16869,ko:K18821	-	-	-	-	ko00000,ko01000	-	-	-	BPL_LplA_LipB
HKD3_k127_5392084_16	1122915.AUGY01000070_gene4254	1.52e-67	236.0	COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli,275UZ@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1003)	yejC	-	-	-	-	-	-	-	-	-	-	-	DUF1003
HKD3_k127_5392084_3	315749.Bcer98_3908	2.097e-150	481.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,1ZC98@1386|Bacillus	91061|Bacilli	C	In Salmonella this enzyme is required for ethanolamine catabolism	pta	-	2.3.1.8,3.6.3.21	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00236,M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	iSB619.SA_RS03155	PTA_PTB
HKD3_k127_5392084_5	1169144.KB910926_gene1174	4.95e-140	449.0	COG3253@1|root,COG3253@2|Bacteria,1TQB2@1239|Firmicutes,4H9YI@91061|Bacilli,1ZAZY@1386|Bacillus	91061|Bacilli	C	May function as heme-dependent peroxidase	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
HKD3_k127_5392084_17	1169144.KB910926_gene1171	2.63e-56	202.0	2CWP1@1|root,32T03@2|Bacteria,1VAD2@1239|Firmicutes,4HKGQ@91061|Bacilli,1ZH2J@1386|Bacillus	91061|Bacilli	S	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA	gerQ	GO:0005575,GO:0005618,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0019538,GO:0030312,GO:0031160,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0071944,GO:1901564	-	ko:K06305	-	-	-	-	ko00000	-	-	-	Spore_GerQ
HKD3_k127_5392084_18	1405.DJ92_2480	8.163e-56	197.0	COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli,1ZGYJ@1386|Bacillus	91061|Bacilli	S	small membrane protein	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
HKD3_k127_5392084_21	1295642.H839_17758	5.396e-08	57.0	2DRJS@1|root,33C32@2|Bacteria,1VPJY@1239|Firmicutes,4HRSY@91061|Bacilli,1WGQ8@129337|Geobacillus	91061|Bacilli	S	Family of unknown function (DUF5327)	ywdI	-	-	-	-	-	-	-	-	-	-	-	DUF5327
HKD3_k127_5392084_15	315730.BcerKBAB4_5189	2.246e-73	250.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,1ZCPY@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	yxeH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HKD3_k127_5399424_0	315730.BcerKBAB4_3713	0.0	1696.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus	91061|Bacilli	F	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD3_k127_5399424_3	198094.BA_4024	9.819e-118	383.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli,1ZBJI@1386|Bacillus	91061|Bacilli	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iYO844.BSU15530	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
HKD3_k127_5399424_2	574376.BAMA_08785	9.142e-171	539.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,1ZBNC@1386|Bacillus	91061|Bacilli	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15540	DHO_dh
HKD3_k127_5399424_5	1027396.LMOSA_27550	1.232e-68	241.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,26JZ7@186820|Listeriaceae	91061|Bacilli	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD3_k127_5399424_4	1169144.KB910924_gene447	9.739e-108	351.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,1ZASD@1386|Bacillus	91061|Bacilli	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15560	Pribosyltran
HKD3_k127_5399424_1	574375.BAGA_26420	1.562e-243	756.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus	91061|Bacilli	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
HKD3_k127_5541137_0	580331.Thit_1886	5.247e-166	531.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,42FWB@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
HKD3_k127_5541137_9	1499689.CCNN01000004_gene157	4.851e-05	46.0	29D8E@1|root,32ZNW@2|Bacteria,1VJ31@1239|Firmicutes,24S0K@186801|Clostridia,36S19@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4417)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4417
HKD3_k127_5541137_6	1262449.CP6013_1583	2.463e-40	157.0	COG0264@1|root,COG0264@2|Bacteria,1VGFM@1239|Firmicutes,25HJI@186801|Clostridia,36VB3@31979|Clostridiaceae	186801|Clostridia	J	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
HKD3_k127_5541137_5	268407.PWYN_20760	3.723e-77	259.0	COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,26YH0@186822|Paenibacillaceae	91061|Bacilli	K	MerR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD3_k127_5541137_2	1262449.CP6013_3885	6.921e-105	342.0	COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,24B8G@186801|Clostridia,36HMK@31979|Clostridiaceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
HKD3_k127_5541137_7	1123009.AUID01000031_gene1253	1.762e-36	145.0	COG4925@1|root,COG4925@2|Bacteria,1VA88@1239|Firmicutes,24N85@186801|Clostridia,26BZW@186813|unclassified Clostridiales	186801|Clostridia	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Cyclophil_like
HKD3_k127_5541137_4	871968.DESME_04865	8.99e-78	261.0	COG1917@1|root,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,265MR@186807|Peptococcaceae	186801|Clostridia	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD3_k127_5541137_1	658086.HMPREF0994_05997	1.517e-117	384.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,27MH4@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
HKD3_k127_5541137_8	994573.T472_0216785	8.35e-07	50.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,36EU1@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
HKD3_k127_5541137_3	994573.T472_0216785	9.388e-86	287.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,36EU1@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
HKD3_k127_5549132_0	1169144.KB910924_gene554	2.02e-188	595.0	COG2200@1|root,COG2200@2|Bacteria,1UADD@1239|Firmicutes,4HCNX@91061|Bacilli,1ZBWD@1386|Bacillus	91061|Bacilli	T	Diguanylate phosphodiesterase	ykuI	-	-	-	-	-	-	-	-	-	-	-	EAL,YkuI_C
HKD3_k127_5549132_8	1169144.KB910924_gene551	1.298e-48	174.0	COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,1ZI15@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ykuJ	-	-	-	-	-	-	-	-	-	-	-	DUF1797
HKD3_k127_5549132_11	315730.BcerKBAB4_3813	1.418e-13	72.0	2CDFG@1|root,2ZRQY@2|Bacteria,1W6MM@1239|Firmicutes,4I24H@91061|Bacilli,1ZKSN@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_10
HKD3_k127_5549132_6	315730.BcerKBAB4_3812	1.693e-70	243.0	COG1978@1|root,COG1978@2|Bacteria,1V6RQ@1239|Firmicutes,4HJAJ@91061|Bacilli,1ZR7F@1386|Bacillus	91061|Bacilli	S	Ribonuclease H-like	ykuK	-	-	ko:K09776	-	-	-	-	ko00000	-	-	-	RNaseH_like
HKD3_k127_5549132_7	574376.BAMA_09280	9.138e-65	225.0	COG0517@1|root,COG0517@2|Bacteria,1V9HN@1239|Firmicutes,4HH3X@91061|Bacilli,1ZGY8@1386|Bacillus	91061|Bacilli	S	CBS domain	ykuL	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_5549132_2	1169144.KB910924_gene546	4.446e-132	426.0	COG0583@1|root,COG0583@2|Bacteria,1TZ6U@1239|Firmicutes,4HB3Y@91061|Bacilli,1ZB8N@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ccpC	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_5549132_3	315730.BcerKBAB4_3808	2.235e-113	369.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,1ZBFG@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapH	-	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU14180	DapH_N,Hexapep
HKD3_k127_5549132_1	1405.DJ92_1077	8.703e-180	569.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,1ZC15@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate	hipO	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.47	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_5549132_4	665952.HMPREF1015_00669	2.882e-106	346.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,1ZCZP@1386|Bacillus	91061|Bacilli	O	Alkyl hydroperoxide reductase	ykuU	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
HKD3_k127_5549132_5	1169144.KB910924_gene542	1.615e-75	255.0	COG0526@1|root,COG0526@2|Bacteria,1V1R4@1239|Firmicutes,4HFWU@91061|Bacilli,1ZBFR@1386|Bacillus	91061|Bacilli	CO	thiol-disulfide	ykuV	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_5697557_1	1380408.AVGH01000005_gene2653	4.144e-95	317.0	COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,4HGNR@91061|Bacilli,21WJR@150247|Anoxybacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_10,Acetyltransf_9,GNAT_acetyltran
HKD3_k127_5697557_2	1405.DJ92_4691	2.759e-59	209.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli,1ZG9C@1386|Bacillus	91061|Bacilli	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HKD3_k127_5697557_0	1169144.KB910937_gene1038	1.14e-125	407.0	29SV9@1|root,31VZX@2|Bacteria,1V9FK@1239|Firmicutes,4IRY8@91061|Bacilli,1ZRZ4@1386|Bacillus	91061|Bacilli	S	Oxalate formate antiporter	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_5697557_3	265729.GS18_0209040	3.232e-31	125.0	COG0500@1|root,COG2226@2|Bacteria,1U9IT@1239|Firmicutes,4HDV5@91061|Bacilli,1ZC30@1386|Bacillus	91061|Bacilli	Q	Methionine biosynthesis protein MetW	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD3_k127_6026393_11	1396.DJ87_894	8.363e-10	60.0	2AN64@1|root,31D41@2|Bacteria,1V7Z3@1239|Firmicutes,4HJDV@91061|Bacilli,1ZFW5@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1885
HKD3_k127_6026393_9	491915.Aflv_1887	1.044e-11	67.0	2EJRA@1|root,33DG3@2|Bacteria,1VKIW@1239|Firmicutes,4HR36@91061|Bacilli	91061|Bacilli	S	SR1 protein	-	-	-	-	-	-	-	-	-	-	-	-	SR1P
HKD3_k127_6026393_4	1169144.KB910924_gene528	2.043e-113	373.0	arCOG13259@1|root,2Z8C5@2|Bacteria,1V23R@1239|Firmicutes,4HB9U@91061|Bacilli,1ZG1S@1386|Bacillus	91061|Bacilli	H	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links	tgl	GO:0000003,GO:0003674,GO:0003810,GO:0003824,GO:0008150,GO:0016740,GO:0016746,GO:0016755,GO:0019954,GO:0030436,GO:0032502,GO:0043934,GO:0140096	2.3.2.13	ko:K00686	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD3_k127_6026393_1	574376.BAMA_09175	4.086e-278	859.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZAR0@1386|Bacillus	91061|Bacilli	E	Arginine	speA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	4.1.1.17,4.1.1.19	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00133,M00134	R00566,R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD3_k127_6026393_2	406124.ACPC01000009_gene1590	6.536e-157	499.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBRG@1386|Bacillus	91061|Bacilli	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
HKD3_k127_6026393_6	1117379.BABA_19671	5.866e-33	129.0	COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,1ZHT9@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0223 family	yktA	-	-	-	-	-	-	-	-	-	-	-	UPF0223
HKD3_k127_6026393_5	574376.BAMA_09165	2.497e-77	264.0	COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,1ZCEH@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0637 family	yktB	-	-	-	-	-	-	-	-	-	-	-	DUF1054
HKD3_k127_6026393_7	260799.BAS3871	6.826e-25	104.0	2DQGP@1|root,336RI@2|Bacteria,1VF4C@1239|Firmicutes,4IDMC@91061|Bacilli,1ZJ9R@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6026393_3	315749.Bcer98_2660	5.683e-117	381.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,1ZAS1@1386|Bacillus	91061|Bacilli	G	Inositol monophosphatase	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HKD3_k127_6026393_0	315749.Bcer98_2658	0.0	1093.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,1ZB9R@1386|Bacillus	91061|Bacilli	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_6026393_10	1430331.EP10_14375	2.542e-10	62.0	2E309@1|root,32Y0U@2|Bacteria,1VEZC@1239|Firmicutes,4HNYA@91061|Bacilli,1WGM9@129337|Geobacillus	91061|Bacilli	S	YlaH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YlaH
HKD3_k127_6046385_7	574375.BAGA_12895	1.907e-97	322.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus	91061|Bacilli	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HKD3_k127_6046385_10	1405.DJ92_2418	1.024e-69	241.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,4HH7C@91061|Bacilli,1ZFK0@1386|Bacillus	91061|Bacilli	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD3_k127_6046385_13	315749.Bcer98_3842	8.316e-59	206.0	COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HH6W@91061|Bacilli,1ZR8Z@1386|Bacillus	91061|Bacilli	S	DoxX	mhqP	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD3_k127_6046385_16	1396.DJ87_3881	3.315e-48	180.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,1ZH51@1386|Bacillus	91061|Bacilli	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD3_k127_6046385_9	574376.BAMA_01410	2.113e-75	255.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,1ZFM4@1386|Bacillus	91061|Bacilli	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD3_k127_6046385_8	1169144.KB910944_gene2326	1.243e-82	280.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli,1ZFKM@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0340 family	ywlG	-	-	-	-	-	-	-	-	-	-	-	DUF436
HKD3_k127_6046385_2	1396.DJ87_3884	4.385e-238	740.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,1ZB9V@1386|Bacillus	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD3_k127_6046385_5	315749.Bcer98_3834	1.788e-122	395.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,1ZASG@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
HKD3_k127_6046385_3	1033734.CAET01000047_gene629	9.261e-226	721.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	prtS	-	3.4.21.110,3.4.21.96	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5
HKD3_k127_6046385_17	1169144.KB910944_gene2329	2.665e-29	119.0	COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,1ZJ1K@1386|Bacillus	91061|Bacilli	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HKD3_k127_6046385_15	315730.BcerKBAB4_5110	3.268e-49	180.0	2E2UM@1|root,30T3H@2|Bacteria,1U2GB@1239|Firmicutes,4IC2I@91061|Bacilli,1ZJ0R@1386|Bacillus	91061|Bacilli	S	ATP synthase	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
HKD3_k127_6046385_6	1169144.KB910944_gene2331	1.066e-116	379.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,1ZB02@1386|Bacillus	91061|Bacilli	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HKD3_k127_6046385_18	1169144.KB910944_gene2332	2.333e-27	112.0	COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,1ZIWP@1386|Bacillus	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD3_k127_6046385_12	1405.DJ92_2404	7.946e-64	222.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
HKD3_k127_6046385_11	574376.BAMA_01365	2.402e-68	236.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HKD3_k127_6046385_0	315749.Bcer98_3827	5.979e-290	894.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,1ZB13@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD3_k127_6046385_4	1169144.KB910944_gene2336	6.153e-139	445.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,1ZCKT@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSB619.SA_RS10970,iYO844.BSU36820	ATP-synt
HKD3_k127_6046385_1	1430331.EP10_10175	4.076e-269	832.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,1WE1N@129337|Geobacillus	91061|Bacilli	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10965	ATP-synt_ab,ATP-synt_ab_N
HKD3_k127_6046385_14	1405.DJ92_2399	1.427e-57	202.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,1ZGET@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
HKD3_k127_6057455_2	666686.B1NLA3E_07545	1.094e-12	68.0	COG2271@1|root,COG2271@2|Bacteria,1UXYK@1239|Firmicutes,4HBU0@91061|Bacilli,1ZCMR@1386|Bacillus	91061|Bacilli	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD3_k127_6057455_0	1211814.CAPG01000003_gene96	4.179e-124	402.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4HBHP@91061|Bacilli,1ZECA@1386|Bacillus	91061|Bacilli	C	COG2086 Electron transfer flavoprotein, beta subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD3_k127_6057455_1	666686.B1NLA3E_07535	1.638e-38	146.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZMI4@1386|Bacillus	91061|Bacilli	C	Electron transfer flavoprotein FAD-binding domain	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Acyl-CoA_dh_1,ETF,ETF_alpha
HKD3_k127_6060570_0	1347369.CCAD010000056_gene4251	1.969e-170	539.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD3_k127_6060570_1	1121422.AUMW01000022_gene1566	1.048e-116	382.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,263R6@186807|Peptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_6070423_2	1169144.KB910942_gene2602	1.901e-108	353.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZBHM@1386|Bacillus	91061|Bacilli	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	yngE	-	-	-	-	-	-	-	-	-	-	iYO844.BSU18210	Carboxyl_trans
HKD3_k127_6070423_1	315749.Bcer98_1806	8.898e-111	363.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	yngF	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD3_k127_6070423_0	1405.DJ92_5090	6.404e-138	443.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1ZC18@1386|Bacillus	91061|Bacilli	E	Hydroxymethylglutaryl-CoA lyase	yngG	GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD3_k127_6070423_4	574376.BAMA_06505	3.556e-25	107.0	COG4770@1|root,COG4770@2|Bacteria,1VEJE@1239|Firmicutes,4HNJG@91061|Bacilli,1ZS1V@1386|Bacillus	91061|Bacilli	I	Biotin carboxyl carrier protein	yngHB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD3_k127_6070423_3	1169144.KB910942_gene2606	3.604e-63	219.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus	91061|Bacilli	I	Biotin carboxylase	yngH	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_6075354_1	574376.BAMA_19685	1.033e-158	507.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HBE4@91061|Bacilli,1ZD5Z@1386|Bacillus	91061|Bacilli	M	Spore Coat	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
HKD3_k127_6075354_0	574376.BAMA_19670	2.818e-267	831.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
HKD3_k127_6075354_2	574376.BAMA_19665	6.214e-60	210.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HKC0@91061|Bacilli,1ZGW4@1386|Bacillus	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HKD3_k127_6113110_58	1499968.TCA2_5335	1.25e-09	60.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HRQH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6113110_59	1382305.AZUC01000018_gene49	1.667e-09	58.0	2DM16@1|root,319V6@2|Bacteria,1V5UE@1239|Firmicutes,4HHYY@91061|Bacilli,26F2J@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6113110_44	1169144.KB910964_gene2952	2.183e-57	203.0	COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,4HJ81@91061|Bacilli,1ZH6S@1386|Bacillus	91061|Bacilli	T	COG0517 FOG CBS domain	ylbB	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_6113110_27	1169144.KB910964_gene2951	1.952e-106	357.0	29G88@1|root,30361@2|Bacteria,1U0G1@1239|Firmicutes,4IN1X@91061|Bacilli,1ZMKM@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3965)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3960,DUF3965
HKD3_k127_6113110_55	1169144.KB910964_gene2950	3.557e-15	79.0	29SS6@1|root,30DY3@2|Bacteria,1UBVX@1239|Firmicutes,4INBH@91061|Bacilli,1ZN6T@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6113110_34	1169144.KB910964_gene2949	5.343e-92	316.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG3103@2|Bacteria,1TRWJ@1239|Firmicutes,4HWZ3@91061|Bacilli,1ZM17@1386|Bacillus	91061|Bacilli	MT	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SH3_3
HKD3_k127_6113110_24	574375.BAGA_27905	3.309e-112	365.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HD73@91061|Bacilli,1ZBNG@1386|Bacillus	91061|Bacilli	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
HKD3_k127_6113110_42	1121929.KB898662_gene482	3.901e-66	234.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,4HAFM@91061|Bacilli	91061|Bacilli	P	abc transporter atp-binding protein	-	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
HKD3_k127_6113110_25	1405.DJ92_3338	3.639e-112	367.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HDSC@91061|Bacilli,1ZAW3@1386|Bacillus	91061|Bacilli	P	binding-protein-dependent transport systems inner membrane component	ssuC	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
HKD3_k127_6113110_15	1405.DJ92_3339	2.498e-160	510.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBUT@91061|Bacilli,1ZQXH@1386|Bacillus	91061|Bacilli	P	ABC transporter substrate-binding protein	thiY	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
HKD3_k127_6113110_40	1396.DJ87_4362	7.46e-72	248.0	COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,1ZH29@1386|Bacillus	91061|Bacilli	H	Transcriptional regulator TenI	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3,5.3.99.10	ko:K00788,ko:K10810	ko00730,ko01100,map00730,map01100	M00127	R03223,R09977,R10712	RC00224,RC02766,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	TMP-TENI
HKD3_k127_6113110_11	1169144.KB910964_gene2947	1.759e-177	562.0	COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,1ZCZM@1386|Bacillus	91061|Bacilli	E	Glycine oxidase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
HKD3_k127_6113110_54	1405.DJ92_3342	7.816e-18	85.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,4HR3T@91061|Bacilli	91061|Bacilli	H	Thiamine biosynthesis	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD3_k127_6113110_20	1196324.A374_07914	1.053e-127	411.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,4HBSI@91061|Bacilli	91061|Bacilli	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
HKD3_k127_6113110_16	315730.BcerKBAB4_0649	4.998e-157	501.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus	91061|Bacilli	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
HKD3_k127_6113110_21	1405.DJ92_3355	6.7e-127	411.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli,1ZD2S@1386|Bacillus	91061|Bacilli	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD3_k127_6113110_9	1169144.KB910964_gene2929	2.635e-212	666.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZDJJ@1386|Bacillus	91061|Bacilli	S	permease	pbuO	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HKD3_k127_6113110_18	574376.BAMA_23900	1.513e-132	427.0	COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZAS0@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	yhxC	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD3_k127_6113110_37	1169144.KB910964_gene2927	1.324e-85	290.0	COG1376@1|root,COG1376@2|Bacteria,1V9XU@1239|Firmicutes,4HKDD@91061|Bacilli,1ZGIN@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ykuD	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
HKD3_k127_6113110_52	574376.BAMA_23915	3.962e-21	96.0	2EAS4@1|root,334U7@2|Bacteria,1VG99@1239|Firmicutes,4HQI1@91061|Bacilli,1ZK2G@1386|Bacillus	91061|Bacilli	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HKD3_k127_6113110_4	1169144.KB910991_gene2734	2.352e-271	848.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,1ZBEM@1386|Bacillus	91061|Bacilli	G	Phosphoglucomutase	pgcA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD3_k127_6113110_47	315749.Bcer98_0639	2.291e-30	121.0	2E2U4@1|root,32XW8@2|Bacteria,1VAT9@1239|Firmicutes,4HN53@91061|Bacilli,1ZHZK@1386|Bacillus	91061|Bacilli	S	YhdB-like protein	yhdB	-	-	-	-	-	-	-	-	-	-	-	YhdB
HKD3_k127_6113110_6	1405.DJ92_3371	6.466e-264	818.0	COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,4HBAW@91061|Bacilli,1ZAT5@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein R	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
HKD3_k127_6113110_49	796606.BMMGA3_09810	1.247e-27	114.0	COG3339@1|root,COG3339@2|Bacteria,1VFBU@1239|Firmicutes,4HPPR@91061|Bacilli,1ZJM4@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HKD3_k127_6113110_32	634956.Geoth_3222	6.047e-96	319.0	COG0861@1|root,COG0861@2|Bacteria,1V1N1@1239|Firmicutes,4HB7Z@91061|Bacilli,1WF19@129337|Geobacillus	91061|Bacilli	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
HKD3_k127_6113110_7	1169144.KB910938_gene1508	6.536e-256	797.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	gapN	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_6113110_3	574375.BAGA_28460	1.947e-272	848.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	yheI	-	-	ko:K18216,ko:K18889	ko02010,map02010	M00635,M00707	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_6113110_0	315730.BcerKBAB4_0758	1.033e-291	908.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	yheH	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K18217,ko:K18890	ko02010,map02010	M00635,M00707	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD3_k127_6113110_50	1408424.JHYI01000013_gene1057	3.491e-26	108.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus	91061|Bacilli	S	spore protein	-	-	-	ko:K06418,ko:K06419	-	-	-	-	ko00000	-	-	-	SASP
HKD3_k127_6113110_51	491915.Aflv_2306	6.623e-25	106.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,21X8F@150247|Anoxybacillus	91061|Bacilli	S	Small, acid-soluble spore proteins, alpha/beta type	B4168_3115	-	-	-	-	-	-	-	-	-	-	-	SASP
HKD3_k127_6113110_57	471223.GWCH70_0620	6.114e-12	69.0	2EH16@1|root,33AT6@2|Bacteria,1VKV6@1239|Firmicutes,4HPH7@91061|Bacilli,1WGUY@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6113110_10	1382358.JHVN01000015_gene665	4.857e-190	598.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,21V8U@150247|Anoxybacillus	91061|Bacilli	P	TOBE domain	msmX	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
HKD3_k127_6113110_45	1295642.H839_02371	8.29e-57	209.0	COG2508@1|root,COG2508@2|Bacteria,1V2FP@1239|Firmicutes,4HG2R@91061|Bacilli,1WE5M@129337|Geobacillus	91061|Bacilli	QT	PucR C-terminal helix-turn-helix domain	lrp	-	-	-	-	-	-	-	-	-	-	-	HTH_30
HKD3_k127_6113110_41	471223.GWCH70_0625	1.193e-71	257.0	COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1WEE9@129337|Geobacillus	91061|Bacilli	HJ	YheC/D like ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD3_k127_6113110_14	1405.DJ92_3442	7.531e-164	527.0	COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HM50@91061|Bacilli,1ZQ3F@1386|Bacillus	91061|Bacilli	HJ	YheC/D like ATP-grasp	yheD	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD3_k127_6113110_35	1033734.CAET01000028_gene4481	2.295e-91	313.0	COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus	91061|Bacilli	HJ	YheC/D like ATP-grasp	yheC	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD3_k127_6113110_31	935837.JAEK01000012_gene343	1.312e-96	332.0	COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus	91061|Bacilli	HJ	YheC/D like ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_YheCD
HKD3_k127_6113110_46	1169144.KB910938_gene1518	5.071e-35	137.0	COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,1ZH14@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0342 family	yheA	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HKD3_k127_6113110_36	1396.DJ87_4202	3.071e-87	292.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HJ3T@91061|Bacilli,1ZQ43@1386|Bacillus	91061|Bacilli	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD3_k127_6113110_19	1396.DJ87_4201	2.481e-132	427.0	COG0561@1|root,COG0561@2|Bacteria,1UY24@1239|Firmicutes,4HA4U@91061|Bacilli,1ZQ4C@1386|Bacillus	91061|Bacilli	S	Haloacid dehalogenase	yhaX	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HKD3_k127_6113110_62	315730.BcerKBAB4_0778	7.917e-07	52.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus	91061|Bacilli	H	coproporphyrinogen III oxidase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD3_k127_6113110_5	1396.DJ87_4198	2.211e-270	843.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD3_k127_6113110_28	1121091.AUMP01000020_gene3690	6.852e-106	347.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_6113110_12	545693.BMQ_3272	1.532e-167	538.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,1ZBIC@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD3_k127_6113110_23	1117108.PAALTS15_06544	1.226e-119	395.0	COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,26S72@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_6113110_33	1243664.CAVL020000008_gene4120	1.847e-92	308.0	COG1136@1|root,COG1136@2|Bacteria,1V2U0@1239|Firmicutes,4HGGC@91061|Bacilli,1ZPYH@1386|Bacillus	91061|Bacilli	V	Hemin ABC transporter ATP-binding protein	hrtA	-	-	ko:K02003,ko:K09814	ko02010,map02010	M00257,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_6113110_26	1405.DJ92_3455	2.735e-110	362.0	COG1024@1|root,COG1024@2|Bacteria,1TRCQ@1239|Firmicutes,4HDUU@91061|Bacilli,1ZARB@1386|Bacillus	91061|Bacilli	I	enoyl-CoA hydratase	yhaR	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD3_k127_6113110_56	634956.Geoth_3184	1.749e-14	75.0	2E4GP@1|root,32ZBV@2|Bacteria,1VF2A@1239|Firmicutes,4HNUS@91061|Bacilli,1WGV6@129337|Geobacillus	91061|Bacilli	S	YhzD-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhzD
HKD3_k127_6113110_17	1396.DJ87_3665	6.197e-151	487.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,1ZC5G@1386|Bacillus	91061|Bacilli	L	DNA repair exonuclease	yhaO	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
HKD3_k127_6113110_8	574375.BAGA_21955	7.827e-232	747.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus	91061|Bacilli	L	AAA domain	yhaN	-	-	-	-	-	-	-	-	-	-	-	AAA_27
HKD3_k127_6113110_13	1169144.KB910954_gene39	1.438e-164	522.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,1ZB1G@1386|Bacillus	91061|Bacilli	L	Shows a 3'-5' exoribonuclease activity	yhaM	GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
HKD3_k127_6113110_53	574376.BAMA_16705	2.993e-20	91.0	2DQFN@1|root,336J9@2|Bacteria,1VJ6N@1239|Firmicutes,4HQ0A@91061|Bacilli,1ZK3U@1386|Bacillus	91061|Bacilli	S	Sporulation protein YhaL	yhaL	-	-	-	-	-	-	-	-	-	-	-	Spore_YhaL
HKD3_k127_6113110_38	1396.DJ87_3652	1.098e-81	275.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,4HH9Q@91061|Bacilli,1ZCJN@1386|Bacillus	91061|Bacilli	K	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA	glpP	GO:0001072,GO:0001678,GO:0003674,GO:0005975,GO:0006066,GO:0006071,GO:0006355,GO:0008150,GO:0008152,GO:0009743,GO:0009746,GO:0009749,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0019400,GO:0019725,GO:0019751,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0033500,GO:0034284,GO:0042221,GO:0042592,GO:0042593,GO:0043242,GO:0043244,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046677,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0055082,GO:0060255,GO:0060567,GO:0065007,GO:0065008,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0080090,GO:0140110,GO:1901615,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
HKD3_k127_6113110_1	574375.BAGA_21905	6.135e-283	873.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1ZB20@1386|Bacillus	91061|Bacilli	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HKD3_k127_6113110_2	1169144.KB910954_gene32	1.394e-273	850.0	COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus	91061|Bacilli	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.1.3.21,1.1.5.3	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	-	R00846,R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HKD3_k127_6113110_30	1169144.KB910927_gene1452	1.586e-103	344.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus	91061|Bacilli	M	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
HKD3_k127_6113110_61	1348908.KI518588_gene2014	1.937e-08	55.0	29SGQ@1|root,30DMQ@2|Bacteria,1UBFG@1239|Firmicutes,4IMU5@91061|Bacilli,1ZKUT@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (Tiny_TM_bacill)	-	-	-	-	-	-	-	-	-	-	-	-	Tiny_TM_bacill
HKD3_k127_6113110_29	315749.Bcer98_0812	5.411e-104	339.0	COG1846@1|root,COG1846@2|Bacteria,1UY04@1239|Firmicutes,4HBQS@91061|Bacilli,1ZBRK@1386|Bacillus	91061|Bacilli	K	Negative regulator of protease production and sporulation	hpr	GO:0000003,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K09682	-	-	-	-	ko00000,ko03000	-	-	-	MarR
HKD3_k127_6113110_48	574375.BAGA_21860	3.375e-28	117.0	COG4980@1|root,COG4980@2|Bacteria,1VAKP@1239|Firmicutes,4HKD5@91061|Bacilli,1ZJ3D@1386|Bacillus	91061|Bacilli	S	YtxH-like protein	yhaH	-	-	-	-	-	-	-	-	-	-	-	YtxH
HKD3_k127_6113110_43	1169144.KB910927_gene1448	4.928e-65	228.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,1ZGI0@1386|Bacillus	91061|Bacilli	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HKD3_k127_6113110_22	315749.Bcer98_0815	3.189e-125	404.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,1ZBAI@1386|Bacillus	91061|Bacilli	V	transporter (ATP-binding protein)	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_6113110_39	545693.BMQ_0591	4.891e-74	261.0	COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,1ZBQG@1386|Bacillus	91061|Bacilli	U	ABC transporter	ecsB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	EcsB
HKD3_k127_6132279_2	1169144.KB910963_gene2894	1.473e-114	380.0	COG0726@1|root,COG0726@2|Bacteria,1VD20@1239|Firmicutes,4HN1H@91061|Bacilli,1ZMHZ@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_6132279_1	1405.DJ92_2956	3.191e-123	406.0	COG0726@1|root,COG0726@2|Bacteria,1VD20@1239|Firmicutes,4HN1H@91061|Bacilli,1ZC2M@1386|Bacillus	91061|Bacilli	G	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_6132279_0	315749.Bcer98_0300	7.175e-163	516.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,1ZBPD@1386|Bacillus	91061|Bacilli	I	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
HKD3_k127_6132279_3	471223.GWCH70_0288	8.817e-89	294.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,1WF79@129337|Geobacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HKD3_k127_6138423_5	545693.BMQ_4442	2.096e-90	299.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD3_k127_6138423_4	1169144.KB910946_gene3649	1.44e-160	512.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,4H9QV@91061|Bacilli,1ZC7E@1386|Bacillus	91061|Bacilli	C	Belongs to the acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
HKD3_k127_6138423_0	574376.BAMA_10155	6.86e-237	739.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZBCS@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	bfmBC	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD3_k127_6138423_2	1169144.KB910946_gene3647	1.488e-179	566.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,1ZCCJ@1386|Bacillus	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
HKD3_k127_6138423_1	1234664.AMRO01000024_gene1898	2.041e-192	602.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1WG13@129337|Geobacillus	91061|Bacilli	C	Transketolase, pyrimidine binding domain	bfmBAB	-	1.2.4.4	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU24040	Transket_pyr,Transketolase_C
HKD3_k127_6138423_3	1405.DJ92_1259	6.714e-174	554.0	COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,1ZC6F@1386|Bacillus	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdB	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD3_k127_6138423_6	574375.BAGA_02300	2.825e-33	129.0	COG1051@1|root,COG1051@2|Bacteria,1V6Q0@1239|Firmicutes,4HIKK@91061|Bacilli,1ZH3B@1386|Bacillus	91061|Bacilli	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_6139539_3	1340434.AXVA01000003_gene2542	1.277e-49	185.0	29SQV@1|root,30DWQ@2|Bacteria,1UBUA@1239|Firmicutes,4IN9P@91061|Bacilli,1ZN3G@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6139539_0	1078085.HMPREF1210_01399	7.555e-247	764.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26EBB@186818|Planococcaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF_1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HKD3_k127_6139539_1	1078085.HMPREF1210_01400	9.453e-176	552.0	COG1396@1|root,COG1396@2|Bacteria,1TSJ6@1239|Firmicutes,4HC63@91061|Bacilli,26H6P@186818|Planococcaceae	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
HKD3_k127_6139539_2	1169144.KB910940_gene2536	4.6e-74	250.0	COG3935@1|root,COG3935@2|Bacteria,1V69W@1239|Firmicutes,4HJM0@91061|Bacilli,1ZG5T@1386|Bacillus	91061|Bacilli	L	Primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2,Phg_2220_C
HKD3_k127_6140213_1	1196324.A374_02439	1.247e-94	314.0	COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli	91061|Bacilli	C	Nitroreductase	ydgI	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD3_k127_6140213_3	1196324.A374_02444	6.084e-43	161.0	COG1846@1|root,COG1846@2|Bacteria,1VD1F@1239|Firmicutes,4HME2@91061|Bacilli	91061|Bacilli	K	Winged helix DNA-binding domain	ydgJ	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD3_k127_6140213_0	1131730.BAVI_06074	9.186e-138	450.0	COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,4HP9Q@91061|Bacilli,1ZBVC@1386|Bacillus	91061|Bacilli	M	Teichuronic acid biosynthesis glycosyltransferase tuaH	tuaH	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K16699	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glyco_trans_1_4,Glycos_transf_2
HKD3_k127_6140213_2	1169144.KB910926_gene1142	1.192e-87	294.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,4IR8J@91061|Bacilli,1ZGTE@1386|Bacillus	91061|Bacilli	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
HKD3_k127_6140213_4	1405.DJ92_5170	6.548e-30	123.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HN1F@91061|Bacilli,1ZHT2@1386|Bacillus	91061|Bacilli	I	Acid phosphatase homologues	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_6144982_1	1196031.ALEG01000061_gene2081	2.625e-177	565.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,1ZDG5@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures	cshB	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
HKD3_k127_6144982_2	1033734.CAET01000068_gene2560	3.495e-159	505.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,1ZBYQ@1386|Bacillus	91061|Bacilli	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
HKD3_k127_6144982_8	574375.BAGA_02970	3.154e-24	106.0	2E5RP@1|root,330GA@2|Bacteria,1VI20@1239|Firmicutes,4HPUF@91061|Bacilli,1ZIUK@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2624)	yqfT	-	-	-	-	-	-	-	-	-	-	-	DUF2624
HKD3_k127_6144982_4	1396.DJ87_582	1.231e-117	383.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,1ZBS5@1386|Bacillus	91061|Bacilli	P	'COG1121 ABC-type Mn Zn transport systems, ATPase component'	zurA	-	-	ko:K02074,ko:K09817	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
HKD3_k127_6144982_3	1405.DJ92_1385	2.149e-137	441.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli,1ZB0A@1386|Bacillus	91061|Bacilli	P	COG1108 ABC-type Mn2 Zn2 transport systems, permease components	zurM	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HKD3_k127_6144982_6	315749.Bcer98_3007	1.764e-64	223.0	COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,1ZG74@1386|Bacillus	91061|Bacilli	P	Belongs to the Fur family	zur	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02076	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD3_k127_6144982_0	1169144.KB910968_gene3371	1.798e-212	662.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H9S1@91061|Bacilli,1ZCV1@1386|Bacillus	91061|Bacilli	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
HKD3_k127_6144982_7	1169144.KB910968_gene3370	2.089e-27	115.0	COG1388@1|root,COG1388@2|Bacteria,1VKC7@1239|Firmicutes,4IS8W@91061|Bacilli,1ZS35@1386|Bacillus	91061|Bacilli	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6144982_5	1169144.KB910968_gene3369	3.158e-66	234.0	COG5521@1|root,COG5521@2|Bacteria,1VFCP@1239|Firmicutes,4HPKY@91061|Bacilli,1ZR00@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
HKD3_k127_6150240_2	665952.HMPREF1015_02110	9.203e-28	113.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus	91061|Bacilli	S	spore protein	sspB	-	-	ko:K06418,ko:K06419,ko:K06420	-	-	-	-	ko00000	-	-	-	SASP
HKD3_k127_6150240_1	1169144.KB910924_gene348	1.685e-28	120.0	2EBFR@1|root,32V8R@2|Bacteria,1VE6Q@1239|Firmicutes,4HNGR@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6150240_0	1131730.BAVI_00605	6.585e-193	611.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli,1ZBQK@1386|Bacillus	91061|Bacilli	V	Mate efflux family protein	yisQ	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD3_k127_6159902_3	1169144.KB910934_gene4340	7.029e-63	222.0	2C2Z4@1|root,2ZV7K@2|Bacteria,1V3JN@1239|Firmicutes,4HIZF@91061|Bacilli,1ZQSD@1386|Bacillus	91061|Bacilli	S	YpjP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YpjP
HKD3_k127_6159902_0	1117108.PAALTS15_20408	2.234e-143	458.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,26T1B@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HKD3_k127_6159902_4	1121091.AUMP01000021_gene3258	3.471e-52	189.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli	91061|Bacilli	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	dfrA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
HKD3_k127_6159902_6	574376.BAMA_01075	5.966e-32	132.0	COG3103@1|root,COG3584@1|root,COG3103@2|Bacteria,COG3584@2|Bacteria,1VJ08@1239|Firmicutes,4HX0N@91061|Bacilli	91061|Bacilli	T	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D,SH3_3
HKD3_k127_6159902_1	1169144.KB910934_gene4332	1.773e-100	331.0	COG1182@1|root,COG1182@2|Bacteria,1UZBY@1239|Firmicutes,4HB1Z@91061|Bacilli,1ZD4D@1386|Bacillus	91061|Bacilli	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
HKD3_k127_6159902_2	315749.Bcer98_1643	1.009e-88	299.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,4HD2E@91061|Bacilli,1ZEYG@1386|Bacillus	91061|Bacilli	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	ypkP	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD3_k127_6159902_7	935837.JAEK01000058_gene1913	3.08e-11	63.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,1ZBJJ@1386|Bacillus	91061|Bacilli	S	protein, Hemolysin III	yplQ	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
HKD3_k127_6160298_2	1403313.AXBR01000005_gene2022	1.33e-228	717.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus	91061|Bacilli	L	DNA helicase	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HKD3_k127_6160298_10	796606.BMMGA3_11750	2.364e-16	81.0	2EMG8@1|root,33F4X@2|Bacteria,1VPGC@1239|Firmicutes,4HSCA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6160298_9	796606.BMMGA3_11755	9.947e-18	88.0	2DRI8@1|root,33BWQ@2|Bacteria,1VPH7@1239|Firmicutes,4HSA2@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5132
HKD3_k127_6160298_0	796606.BMMGA3_11760	0.0	1480.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus	91061|Bacilli	P	COG0474 Cation transport ATPase	pacL	-	3.6.3.2,3.6.3.6,3.6.3.8	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.23,3.A.3.3,3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD3_k127_6160298_8	796606.BMMGA3_11765	1.357e-20	96.0	2EJ4M@1|root,33CVV@2|Bacteria,1VKTH@1239|Firmicutes,4HSW9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6160298_7	796606.BMMGA3_11770	2.815e-31	126.0	2E8FQ@1|root,332U1@2|Bacteria,1VEXY@1239|Firmicutes,4HQB2@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6160298_6	997296.PB1_04490	1.775e-34	134.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,1ZHX0@1386|Bacillus	91061|Bacilli	T	Belongs to the UPF0237 family	XK27_08630	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
HKD3_k127_6160298_1	1340434.AXVA01000015_gene620	5.712e-257	796.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,1ZDKS@1386|Bacillus	91061|Bacilli	S	UPF0210 protein	XK27_08635	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
HKD3_k127_6160298_3	796606.BMMGA3_09775	3.322e-147	476.0	COG0477@1|root,COG2814@2|Bacteria,1TQKU@1239|Firmicutes,4HA5Q@91061|Bacilli,1ZCSQ@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	yybF1	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
HKD3_k127_6160298_4	279010.BL00467	2.144e-106	352.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HDHR@91061|Bacilli,1ZQ2H@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_6160298_5	666686.B1NLA3E_04280	3.634e-103	343.0	COG1305@1|root,COG1305@2|Bacteria,1V4HE@1239|Firmicutes,4HD3Q@91061|Bacilli,1ZGN3@1386|Bacillus	91061|Bacilli	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,Bact_transglu_N,Transglut_core
HKD3_k127_6161296_1	1169144.KB910928_gene1982	2.747e-198	621.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZD06@1386|Bacillus	91061|Bacilli	G	COG1363 Cellulase M and related proteins	ysdC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD3_k127_6161296_4	1169144.KB910928_gene1975	2.12e-25	106.0	2E3SP@1|root,32YQ7@2|Bacteria,1VFJP@1239|Firmicutes,4HNJI@91061|Bacilli,1ZIXT@1386|Bacillus	91061|Bacilli	S	Belongs to the SspI family	sspI	-	-	ko:K06426	-	-	-	-	ko00000	-	-	-	SSPI
HKD3_k127_6161296_3	574376.BAMA_02580	5.612e-110	361.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,1ZBTY@1386|Bacillus	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_6161296_2	1169144.KB910928_gene1973	1.513e-185	585.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,1ZANR@1386|Bacillus	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HKD3_k127_6161296_0	1169144.KB910928_gene1972	3.299e-264	821.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HKD3_k127_6166709_0	649747.HMPREF0083_05281	1.505e-229	718.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
HKD3_k127_6166709_1	649747.HMPREF0083_05280	4.209e-194	610.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,26T4S@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_6175239_9	315749.Bcer98_0124	3.086e-186	585.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,1ZCEG@1386|Bacillus	91061|Bacilli	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HKD3_k127_6175239_30	1396.DJ87_5329	4.018e-77	260.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1ZFMY@1386|Bacillus	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
HKD3_k127_6175239_45	574376.BAMA_11410	3.633e-23	99.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,1ZITD@1386|Bacillus	91061|Bacilli	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
HKD3_k127_6175239_22	1405.DJ92_2734	7.76e-91	300.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,1ZBWE@1386|Bacillus	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
HKD3_k127_6175239_37	1169144.KB910959_gene3995	3.72e-59	206.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,1ZG7C@1386|Bacillus	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
HKD3_k127_6175239_20	574375.BAGA_17305	5.545e-94	310.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,1ZCR5@1386|Bacillus	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
HKD3_k127_6175239_32	198467.NP92_09240	3.876e-73	248.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,21VNE@150247|Anoxybacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
HKD3_k127_6175239_44	260799.BAS0123	4.519e-34	131.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,1ZHVE@1386|Bacillus	91061|Bacilli	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
HKD3_k127_6175239_19	1396.DJ87_5336	2.071e-102	334.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,1ZB6T@1386|Bacillus	91061|Bacilli	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
HKD3_k127_6175239_39	315749.Bcer98_0115	4.259e-53	188.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,1ZGZQ@1386|Bacillus	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
HKD3_k127_6175239_34	574375.BAGA_17330	1.344e-67	231.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,1ZG7H@1386|Bacillus	91061|Bacilli	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
HKD3_k127_6175239_42	1169144.KB910959_gene3988	1.454e-46	168.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,1ZH2Q@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
HKD3_k127_6175239_47	1120973.AQXL01000112_gene1081	3.935e-17	82.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
HKD3_k127_6175239_29	634956.Geoth_0137	7.79e-79	264.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,1WE2W@129337|Geobacillus	91061|Bacilli	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HKD3_k127_6175239_14	315749.Bcer98_0110	3.865e-127	407.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,1ZBA9@1386|Bacillus	91061|Bacilli	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HKD3_k127_6175239_36	1169144.KB910959_gene3984	1.113e-61	213.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,1ZG6U@1386|Bacillus	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
HKD3_k127_6175239_41	574376.BAMA_11480	4.069e-48	173.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,1ZGXY@1386|Bacillus	91061|Bacilli	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
HKD3_k127_6175239_11	441769.ABFU01000005_gene2872	7.551e-163	514.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,1ZCQP@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
HKD3_k127_6175239_43	1169144.KB910959_gene3981	2.796e-45	166.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,1ZH09@1386|Bacillus	91061|Bacilli	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
HKD3_k127_6175239_18	574376.BAMA_11495	4.357e-109	355.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,1ZBG9@1386|Bacillus	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HKD3_k127_6175239_17	574376.BAMA_11500	6.898e-111	360.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,1ZCM8@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HKD3_k127_6175239_35	491915.Aflv_0104	8.419e-66	226.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,21X2X@150247|Anoxybacillus	91061|Bacilli	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HKD3_k127_6175239_49	1033734.CAET01000080_gene3330	2.604e-07	52.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,1ZGA6@1386|Bacillus	91061|Bacilli	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HKD3_k127_6175239_6	1499685.CCFJ01000033_gene36	3.497e-237	735.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,1ZCZK@1386|Bacillus	91061|Bacilli	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HKD3_k127_6175239_2	315749.Bcer98_0101	0.0	1239.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,1ZBS4@1386|Bacillus	91061|Bacilli	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD3_k127_6175239_24	315749.Bcer98_0100	5.497e-90	297.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,1ZBVR@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HKD3_k127_6175239_28	315749.Bcer98_0099	1.148e-80	269.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,1ZFM9@1386|Bacillus	91061|Bacilli	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HKD3_k127_6175239_1	315749.Bcer98_0097	0.0	2223.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HKD3_k127_6175239_0	1405.DJ92_2709	0.0	2242.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HKD3_k127_6175239_23	315749.Bcer98_0095	4.691e-90	301.0	COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,1ZBPR@1386|Bacillus	91061|Bacilli	J	Methyltransferase	rsmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
HKD3_k127_6175239_38	1033734.CAET01000080_gene3321	1.454e-53	190.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,1ZG84@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HKD3_k127_6175239_31	1403313.AXBR01000025_gene4990	5.162e-76	259.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HKD3_k127_6175239_13	1169144.KB910959_gene3968	3.475e-127	409.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HKD3_k127_6175239_26	1132442.KB889752_gene3442	1.176e-87	290.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,1ZFIG@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HKD3_k127_6175239_21	1396.DJ87_5363	2.075e-93	308.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,1ZBRH@1386|Bacillus	91061|Bacilli	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HKD3_k127_6175239_46	574376.BAMA_11580	2.836e-21	93.0	COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,1ZIY2@1386|Bacillus	91061|Bacilli	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HKD3_k127_6175239_48	260799.BAS0094	8.15e-16	78.0	COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,1ZKEU@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD3_k127_6175239_15	1169144.KB910959_gene3964	5.844e-118	381.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,1ZBEV@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD3_k127_6175239_33	574376.BAMA_11590	4.171e-70	241.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,1ZCMG@1386|Bacillus	91061|Bacilli	S	RNA-binding protein containing a PIN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
HKD3_k127_6175239_12	1169144.KB910959_gene3962	1.021e-130	420.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD3_k127_6175239_40	315749.Bcer98_0085	5.273e-52	187.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,1ZH0Z@1386|Bacillus	91061|Bacilli	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
HKD3_k127_6175239_4	574376.BAMA_11605	5.059e-257	798.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,1ZB69@1386|Bacillus	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HKD3_k127_6175239_16	491915.Aflv_0083	1.363e-115	375.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,21V2S@150247|Anoxybacillus	91061|Bacilli	E	Serine acetyltransferase, N-terminal	cysE	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02865,iYO844.BSU00930	Hexapep,SATase_N
HKD3_k127_6175239_5	315749.Bcer98_0082	7.497e-251	780.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,1ZAWK@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065	6.1.1.24	ko:K09698	ko00970,ko01100,map00970,map01100	M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSB619.SA_RS02860	tRNA-synt_1c
HKD3_k127_6175239_27	315749.Bcer98_0081	1.177e-86	287.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,1ZB1U@1386|Bacillus	91061|Bacilli	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
HKD3_k127_6175239_25	1405.DJ92_2693	1.042e-89	301.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
HKD3_k127_6175239_10	545693.BMQ_0110	3.748e-166	529.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,1ZB5A@1386|Bacillus	91061|Bacilli	S	COG4956 Integral membrane protein (PIN domain superfamily)	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TRAM
HKD3_k127_6175239_8	198094.BA_0082	1.403e-192	605.0	COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,4HAQP@91061|Bacilli,1ZBIY@1386|Bacillus	91061|Bacilli	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
HKD3_k127_6175239_3	1405.DJ92_2690	1.404e-260	807.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
HKD3_k127_6175239_7	1169144.KB910959_gene3952	8.034e-194	607.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD3_k127_6182654_2	445973.CLOBAR_00769	4.098e-37	140.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,24KKM@186801|Clostridia	186801|Clostridia	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6182654_5	411467.BACCAP_04464	4.516e-05	48.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6182654_4	1291050.JAGE01000001_gene2814	8.742e-12	67.0	2DCZJ@1|root,2ZFXV@2|Bacteria,1W3NQ@1239|Firmicutes,254T6@186801|Clostridia,3WRAF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6182654_1	1121289.JHVL01000050_gene2020	5.399e-124	408.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia,36EXJ@31979|Clostridiaceae	186801|Clostridia	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
HKD3_k127_6182654_0	1408422.JHYF01000020_gene1828	0.0	1240.0	COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,24C4U@186801|Clostridia,36G9Z@31979|Clostridiaceae	186801|Clostridia	F	TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
HKD3_k127_6182654_3	350688.Clos_1159	3.9e-17	81.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,249TX@186801|Clostridia,36F63@31979|Clostridiaceae	186801|Clostridia	C	FMN-dependent	lldD	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
HKD3_k127_6185231_21	1444310.JANV01000056_gene443	2.87e-17	81.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,1ZAZT@1386|Bacillus	91061|Bacilli	EJ	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD3_k127_6185231_5	315730.BcerKBAB4_1417	7.009e-165	523.0	COG0492@1|root,COG0492@2|Bacteria,1TQGS@1239|Firmicutes,4HBIS@91061|Bacilli,1ZCBR@1386|Bacillus	91061|Bacilli	O	COG0492 Thioredoxin reductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
HKD3_k127_6185231_22	198094.BA_1513	5.122e-06	53.0	29T38@1|root,30E9S@2|Bacteria,1UCAM@1239|Firmicutes,4INT2@91061|Bacilli,1ZNWX@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF3961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3961
HKD3_k127_6185231_2	574375.BAGA_07265	8.04e-258	797.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gudB	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.2	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD3_k127_6185231_10	1169144.KB910925_gene199	3.856e-95	315.0	COG4862@1|root,COG4862@2|Bacteria,1V1B7@1239|Firmicutes,4HBM5@91061|Bacilli,1ZF7G@1386|Bacillus	91061|Bacilli	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC	mecB	GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
HKD3_k127_6185231_8	1196031.ALEG01000019_gene2852	2.988e-118	387.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1TQ3N@1239|Firmicutes,4HC1T@91061|Bacilli,1ZR6Y@1386|Bacillus	91061|Bacilli	K	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
HKD3_k127_6185231_15	1405.DJ92_4135	1.512e-70	246.0	COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus	91061|Bacilli	S	Calcineurin-like phosphoesterase superfamily domain	ypbG	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
HKD3_k127_6185231_20	574376.BAMA_13910	8.457e-28	118.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ebpS	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD3_k127_6185231_18	574375.BAGA_07240	3.556e-63	222.0	COG1266@1|root,COG1266@2|Bacteria,1V4WK@1239|Firmicutes,4HHKM@91061|Bacilli,1ZEBP@1386|Bacillus	91061|Bacilli	S	metal-dependent membrane protease	ypbD	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_6185231_4	574376.BAMA_13900	1.745e-176	566.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus	91061|Bacilli	L	DNA helicase	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
HKD3_k127_6185231_16	545693.BMQ_4362	3.94e-70	250.0	COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ypbB	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_40,RQC
HKD3_k127_6185231_19	1294265.JCM21738_66	6.262e-45	164.0	COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,1ZHTS@1386|Bacillus	91061|Bacilli	C	Ferredoxin	fer	GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
HKD3_k127_6185231_13	315730.BcerKBAB4_1404	3.839e-81	278.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,1ZG7K@1386|Bacillus	91061|Bacilli	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
HKD3_k127_6185231_11	1297581.H919_01430	1.856e-88	294.0	COG0221@1|root,COG0221@2|Bacteria,1V2DF@1239|Firmicutes,4HFUG@91061|Bacilli,21W3W@150247|Anoxybacillus	91061|Bacilli	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
HKD3_k127_6185231_12	1169144.KB910925_gene208	2.45e-82	280.0	COG3064@1|root,COG3064@2|Bacteria,1VNZ6@1239|Firmicutes,4HY6U@91061|Bacilli,1ZHFH@1386|Bacillus	91061|Bacilli	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6185231_17	198094.BA_1500	2.047e-67	235.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1V3ZU@1239|Firmicutes,4I27X@91061|Bacilli,1ZGNS@1386|Bacillus	91061|Bacilli	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
HKD3_k127_6185231_9	1295642.H839_11859	1.083e-97	321.0	COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,1WEZU@129337|Geobacillus	91061|Bacilli	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HKD3_k127_6185231_1	1169144.KB910925_gene211	3.419e-267	833.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
HKD3_k127_6185231_6	574376.BAMA_13860	3.577e-136	436.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZC0F@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_6185231_3	315730.BcerKBAB4_1398	3.038e-183	580.0	COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli,1ZBH9@1386|Bacillus	91061|Bacilli	O	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'	resC	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
HKD3_k127_6185231_0	1169144.KB910925_gene214	7.176e-271	842.0	COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus	91061|Bacilli	O	COG1333 ResB protein required for cytochrome c biosynthesis	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
HKD3_k127_6185231_14	260799.BAS1383	8.19e-78	264.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus	91061|Bacilli	CO	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_6185231_7	1405.DJ92_4120	1.13e-119	387.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,1ZBNQ@1386|Bacillus	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD3_k127_6192259_0	1134413.ANNK01000002_gene2944	0.0	1028.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,4HD5Z@91061|Bacilli,1ZBHK@1386|Bacillus	91061|Bacilli	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
HKD3_k127_6192259_14	866895.HBHAL_5018	2.069e-38	152.0	2B2QS@1|root,31VAP@2|Bacteria,1V7HH@1239|Firmicutes,4HJ7I@91061|Bacilli,3NF8Q@45667|Halobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6192259_1	1305836.AXVE01000011_gene1140	1.246e-291	922.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26CYX@186818|Planococcaceae	91061|Bacilli	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_9
HKD3_k127_6192259_4	1236973.JCM9157_1540	1.018e-229	722.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HCD9@91061|Bacilli,1ZF8E@1386|Bacillus	91061|Bacilli	EH	Thiamine pyrophosphate enzyme, central domain	ilvB1	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD3_k127_6192259_12	545243.BAEV01000105_gene814	9.88e-75	253.0	COG0698@1|root,COG0698@2|Bacteria,1V1W8@1239|Firmicutes,24F83@186801|Clostridia,36I6F@31979|Clostridiaceae	186801|Clostridia	G	TIGRFAM ribose 5-phosphate isomerase B	rpiB2	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD3_k127_6192259_9	1178537.BA1_09741	7.176e-124	402.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,1ZD69@1386|Bacillus	91061|Bacilli	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	yxkD	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_6192259_10	1499685.CCFJ01000057_gene758	3.265e-85	292.0	COG0454@1|root,COG0456@2|Bacteria,1V4T1@1239|Firmicutes,4HDYC@91061|Bacilli,1ZDHN@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_6192259_3	649747.HMPREF0083_06251	1.433e-233	729.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HT98@91061|Bacilli,277FI@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_6192259_6	649747.HMPREF0083_06249	1.629e-185	589.0	COG0531@1|root,COG0531@2|Bacteria,1TPVA@1239|Firmicutes,4HCI3@91061|Bacilli,274S0@186822|Paenibacillaceae	91061|Bacilli	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K14052	-	-	-	-	ko00000,ko02000	2.A.3.1.13	-	-	AA_permease,AA_permease_2
HKD3_k127_6192259_2	1118054.CAGW01000050_gene1182	1.065e-245	766.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD3_k127_6192259_13	545693.BMQ_1548	1.703e-73	252.0	COG1280@1|root,COG1280@2|Bacteria,1V4SU@1239|Firmicutes,4HI0S@91061|Bacilli,1ZHFB@1386|Bacillus	91061|Bacilli	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_6192259_8	1423321.AS29_09245	9.759e-139	449.0	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,1ZCJF@1386|Bacillus	91061|Bacilli	S	tRNA 2-selenouridine synthase	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD3_k127_6192259_7	1122915.AUGY01000093_gene3627	9.539e-180	567.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,26UJA@186822|Paenibacillaceae	91061|Bacilli	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HKD3_k127_6192259_5	649747.HMPREF0083_00008	4.023e-194	610.0	COG1840@1|root,COG1840@2|Bacteria,1TR2S@1239|Firmicutes,4HC4U@91061|Bacilli,26RY4@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter substrate-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
HKD3_k127_6192259_11	748727.CLJU_c26310	1.282e-77	270.0	COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,24G1T@186801|Clostridia,36IF5@31979|Clostridiaceae	186801|Clostridia	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD3_k127_6192259_15	1078085.HMPREF1210_03086	2.52e-30	121.0	COG4132@1|root,COG4132@2|Bacteria,1TRF0@1239|Firmicutes,4HCV5@91061|Bacilli	91061|Bacilli	P	ABC transporter (permease)	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
HKD3_k127_6207205_4	1450694.BTS2_2561	1.03e-106	349.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,1ZB5N@1386|Bacillus	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD3_k127_6207205_0	1405.DJ92_2242	0.0	1418.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD3_k127_6207205_7	1405.DJ92_2243	9.774e-88	292.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,1ZFW8@1386|Bacillus	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HKD3_k127_6207205_10	574376.BAMA_00865	2.125e-33	128.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZI6D@1386|Bacillus	91061|Bacilli	K	cold-shock protein	cspC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD3_k127_6207205_8	574376.BAMA_00870	2.209e-62	222.0	COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,1ZG88@1386|Bacillus	91061|Bacilli	S	Phosphoribosyl transferase domain	comFC	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
HKD3_k127_6207205_1	1169144.KB910975_gene2398	6.122e-166	535.0	COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,1ZBXC@1386|Bacillus	91061|Bacilli	L	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)	comFA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K02240	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1	-	-	DEAD,Helicase_C,ResIII
HKD3_k127_6207205_5	1169144.KB910975_gene2397	9.626e-99	335.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	-	-	-	ko:K19223,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60
HKD3_k127_6207205_9	1169144.KB910975_gene2396	3.935e-52	185.0	COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,1ZH23@1386|Bacillus	91061|Bacilli	K	transcriptional	yodB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	HxlR
HKD3_k127_6207205_2	574376.BAMA_00890	6.092e-132	426.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,1ZAQH@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD3_k127_6207205_6	1396.DJ87_4013	4.948e-98	324.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,1ZAXD@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1949)	yvyE	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF1949,UPF0029
HKD3_k127_6207205_3	1405.DJ92_2251	3.088e-131	428.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4IQSP@91061|Bacilli,1ZRN9@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD3_k127_6218383_4	315730.BcerKBAB4_1146	7.654e-68	233.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
HKD3_k127_6218383_2	574375.BAGA_20590	2.534e-93	309.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,1ZBB7@1386|Bacillus	91061|Bacilli	EH	Anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD3_k127_6218383_0	574375.BAGA_20595	7.81e-188	599.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus	91061|Bacilli	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD3_k127_6218383_6	1169144.KB910969_gene2103	3.637e-11	63.0	29T23@1|root,30E8J@2|Bacteria,1UC91@1239|Firmicutes,4INRE@91061|Bacilli,1ZNU5@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6218383_5	1396.DJ87_3459	3.047e-19	92.0	COG5492@1|root,COG5492@2|Bacteria,1W453@1239|Firmicutes,4INDG@91061|Bacilli,1ZNAX@1386|Bacillus	91061|Bacilli	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HKD3_k127_6218383_1	574376.BAMA_17620	1.229e-119	391.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,4HB57@91061|Bacilli,1ZCN9@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	yetK	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_6218383_3	1169144.KB910969_gene2099	5.863e-90	301.0	COG2382@1|root,COG2382@2|Bacteria,1UCAC@1239|Firmicutes,4HC02@91061|Bacilli,1ZBAQ@1386|Bacillus	91061|Bacilli	P	COG2382 Enterochelin esterase and related enzymes	yjcH	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
HKD3_k127_6280363_0	665952.HMPREF1015_03129	3.7e-241	763.0	COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,1ZCFV@1386|Bacillus	91061|Bacilli	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	ykcB	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_6280363_1	1042163.BRLA_c003340	1.059e-60	212.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,26QPA@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HKD3_k127_6280559_3	585.DR95_3559	1.713e-107	352.0	COG0624@1|root,COG0624@2|Bacteria,1N20R@1224|Proteobacteria,1RYRN@1236|Gammaproteobacteria,3Z3CE@583|Proteus	1236|Gammaproteobacteria	E	Peptidase dimerisation domain	ygeY	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_6280559_0	1395513.P343_13335	3.672e-241	755.0	COG3653@1|root,COG3653@2|Bacteria,1TSGD@1239|Firmicutes,4HBQ4@91061|Bacilli	91061|Bacilli	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HKD3_k127_6280559_4	1274524.BSONL12_13566	1.028e-100	334.0	COG0778@1|root,COG0778@2|Bacteria,1V2G8@1239|Firmicutes,4HTWH@91061|Bacilli,1ZQFV@1386|Bacillus	91061|Bacilli	C	Nitroreductase family	-	-	1.5.1.39	ko:K19286	ko00740,ko01100,map00740,map01100	-	R05705,R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
HKD3_k127_6280559_7	1123239.KB898626_gene690	3.523e-18	87.0	COG1359@1|root,COG1359@2|Bacteria,1VG4T@1239|Firmicutes,4HPNQ@91061|Bacilli	91061|Bacilli	S	monooxygenase	ycnE	GO:0003674,GO:0003824	-	-	-	-	-	-	-	-	-	-	ABM
HKD3_k127_6280559_5	1196029.ALIM01000034_gene1737	7.519e-38	144.0	COG0640@1|root,COG0640@2|Bacteria,1VAK2@1239|Firmicutes,4HMC7@91061|Bacilli,1ZIM8@1386|Bacillus	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD3_k127_6280559_6	580327.Tthe_0184	6.63e-33	133.0	COG4194@1|root,COG4194@2|Bacteria,1V3Z3@1239|Firmicutes,24KZ8@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
HKD3_k127_6280559_1	1405.DJ92_4034	2.685e-201	635.0	COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus	91061|Bacilli	V	Multidrug efflux pump	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HKD3_k127_6280559_8	1461580.CCAS010000041_gene3287	2e-13	76.0	COG4326@1|root,COG4326@2|Bacteria,1TPEA@1239|Firmicutes,4HBPW@91061|Bacilli,1ZBFU@1386|Bacillus	91061|Bacilli	S	COG4326 Sporulation control protein	spo0M	-	-	ko:K06377	-	-	-	-	ko00000	-	-	-	Spo0M
HKD3_k127_6280559_2	574376.BAMA_13405	3.739e-129	419.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,1ZD80@1386|Bacillus	91061|Bacilli	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD3_k127_6280559_9	235909.GK1358	0.0006879	45.0	COG4326@1|root,COG4326@2|Bacteria,1VHE9@1239|Firmicutes,4HP75@91061|Bacilli,1WGB5@129337|Geobacillus	91061|Bacilli	S	SpoOM protein	-	-	-	ko:K06377	-	-	-	-	ko00000	-	-	-	Spo0M
HKD3_k127_6293435_3	1463909.KL585953_gene5542	5.871e-06	52.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_6293435_2	1295642.H839_16868	4.301e-22	106.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	ko:K17733,ko:K19304	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Amidase_3,CHAP,Lipase_GDSL,LysM
HKD3_k127_6293435_1	1347369.CCAD010000086_gene1745	2.096e-81	292.0	29GY5@1|root,303VU@2|Bacteria,1V3H3@1239|Firmicutes,4IRJN@91061|Bacilli,1ZRV4@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2357,PDDEXK_7
HKD3_k127_6293435_0	1121091.AUMP01000001_gene563	1.606e-189	611.0	COG1401@1|root,COG1401@2|Bacteria,1TRK1@1239|Firmicutes,4HDE2@91061|Bacilli	91061|Bacilli	V	COG1401 GTPase subunit of restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,DUF3578
HKD3_k127_6341597_0	1145276.T479_18745	2.893e-147	487.0	COG0642@1|root,COG0745@1|root,COG2972@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2972@2|Bacteria,1TRIG@1239|Firmicutes,4HK60@91061|Bacilli,3J078@400634|Lysinibacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,Response_reg
HKD3_k127_6341597_1	1274374.CBLK010000061_gene634	4.62e-105	347.0	COG3947@1|root,COG3947@2|Bacteria,1V85E@1239|Firmicutes,4HGJR@91061|Bacilli,26S06@186822|Paenibacillaceae	91061|Bacilli	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Response_reg,Trans_reg_C
HKD3_k127_6341597_2	1211035.CD30_04750	1.603e-87	301.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,3J095@400634|Lysinibacillus	91061|Bacilli	T	Membrane-associated sensor domain	gmr	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE3,PAS_8,PAS_9
HKD3_k127_6351124_2	315749.Bcer98_2411	2.671e-30	119.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,1ZCZN@1386|Bacillus	91061|Bacilli	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
HKD3_k127_6351124_1	1169144.KB910938_gene1527	6.707e-66	229.0	2AD85@1|root,312X5@2|Bacteria,1V735@1239|Firmicutes,4HIXA@91061|Bacilli,1ZGBJ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6351124_0	1169144.KB910928_gene1961	1.228e-187	592.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,1ZBVG@1386|Bacillus	91061|Bacilli	J	Methyltransferase	ywbD	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HKD3_k127_6351707_3	1169144.KB910924_gene427	2.837e-215	675.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,1ZCWU@1386|Bacillus	91061|Bacilli	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
HKD3_k127_6351707_5	1169144.KB910924_gene428	1.193e-158	504.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,1ZBSP@1386|Bacillus	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
HKD3_k127_6351707_9	1169144.KB910924_gene429	6.855e-72	245.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HHMA@91061|Bacilli,1ZGES@1386|Bacillus	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD3_k127_6351707_1	1347086.CCBA010000030_gene104	0.0	1050.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HKD3_k127_6351707_4	1169144.KB910924_gene431	1.835e-187	592.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD3_k127_6351707_11	1169144.KB910924_gene432	5.053e-24	102.0	COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,1ZIVD@1386|Bacillus	91061|Bacilli	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
HKD3_k127_6351707_7	198094.BA_4009	2.545e-107	351.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,1ZBZI@1386|Bacillus	91061|Bacilli	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15680	Guanylate_kin
HKD3_k127_6351707_10	1169144.KB910924_gene434	1.429e-40	151.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,4HKDP@91061|Bacilli,1ZHVQ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0296 family	ylzA	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HKD3_k127_6351707_6	1169144.KB910924_gene435	4.873e-125	407.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus	91061|Bacilli	S	stress-induced protein	yloC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD3_k127_6351707_0	574375.BAGA_00775	0.0	1373.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus	91061|Bacilli	P	COG0474 Cation transport ATPase	yloB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	iYO844.BSU15650	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD3_k127_6351707_2	315749.Bcer98_2527	4.11e-270	841.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus	91061|Bacilli	K	RNA-binding protein homologous to eukaryotic snRNP	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
HKD3_k127_6351707_8	1034347.CAHJ01000025_gene3488	4.946e-79	266.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZAR0@1386|Bacillus	91061|Bacilli	E	Arginine	speA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	4.1.1.17,4.1.1.19	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00133,M00134	R00566,R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD3_k127_6390030_15	1405.DJ92_1288	5.693e-37	145.0	29WYG@1|root,30IKQ@2|Bacteria,1V4Y2@1239|Firmicutes,4HI5K@91061|Bacilli,1ZHEH@1386|Bacillus	91061|Bacilli	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
HKD3_k127_6390030_14	574376.BAMA_10285	2.368e-52	190.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,1ZGFF@1386|Bacillus	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD3_k127_6390030_2	1405.DJ92_1285	2.014e-262	811.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1ZC56@1386|Bacillus	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD3_k127_6390030_12	574375.BAGA_02445	4.862e-57	201.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,1ZG6N@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yqhY	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD3_k127_6390030_13	1405.DJ92_1283	1.945e-53	190.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus	91061|Bacilli	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HKD3_k127_6390030_6	1033734.CAET01000024_gene1190	9.638e-144	460.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HKD3_k127_6390030_4	1169144.KB910946_gene3665	3.913e-199	629.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HKD3_k127_6390030_16	574376.BAMA_10255	5.832e-26	108.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,1ZIVS@1386|Bacillus	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HKD3_k127_6390030_8	315749.Bcer98_2871	7.213e-136	437.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,1ZC4G@1386|Bacillus	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_6390030_0	1396.DJ87_686	0.0	1098.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,1ZBHF@1386|Bacillus	91061|Bacilli	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HKD3_k127_6390030_5	1396.DJ87_687	5.613e-144	461.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,1ZBDS@1386|Bacillus	91061|Bacilli	J	rRNA methylase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HKD3_k127_6390030_11	574376.BAMA_10235	6.799e-84	280.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,1ZFJ8@1386|Bacillus	91061|Bacilli	K	Regulates arginine biosynthesis genes	argR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
HKD3_k127_6390030_1	1169144.KB910946_gene3658	8.426e-272	847.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,1ZC8B@1386|Bacillus	91061|Bacilli	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HKD3_k127_6390030_3	1405.DJ92_1274	1.736e-215	674.0	COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,4H9TW@91061|Bacilli,1ZB04@1386|Bacillus	91061|Bacilli	M	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S55
HKD3_k127_6390030_7	935837.JAEK01000001_gene2360	5.633e-139	446.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,4HA1M@91061|Bacilli,1ZBNB@1386|Bacillus	91061|Bacilli	KT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	GO:0000003,GO:0000156,GO:0000160,GO:0000910,GO:0003674,GO:0006355,GO:0007049,GO:0007154,GO:0007165,GO:0008150,GO:0008356,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019954,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032506,GO:0035556,GO:0042173,GO:0042710,GO:0043934,GO:0043937,GO:0043938,GO:0044010,GO:0044085,GO:0044764,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051252,GO:0051301,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090529,GO:0090604,GO:0090606,GO:1903506,GO:2000112,GO:2001141	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
HKD3_k127_6390030_18	315730.BcerKBAB4_4011	5.107e-12	66.0	COG3093@1|root,COG3093@2|Bacteria,1VNWW@1239|Firmicutes,4HRUI@91061|Bacilli,1ZK0J@1386|Bacillus	91061|Bacilli	K	YycC-like protein	yycC	-	-	-	-	-	-	-	-	-	-	-	YycC
HKD3_k127_6390030_17	1405.DJ92_1267	6.143e-23	100.0	2E54T@1|root,32ZXQ@2|Bacteria,1VFDB@1239|Firmicutes,4HNU1@91061|Bacilli,1ZIWH@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2627)	yqzF	-	-	-	-	-	-	-	-	-	-	-	DUF2627
HKD3_k127_6390030_10	1405.DJ92_1265	1.663e-123	402.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4HBSK@91061|Bacilli,1ZC49@1386|Bacillus	91061|Bacilli	C	phosphate butyryltransferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	iYO844.BSU24090	PTA_PTB
HKD3_k127_6390030_9	491915.Aflv_0959	3.67e-130	417.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,21WS5@150247|Anoxybacillus	91061|Bacilli	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD3_k127_6392922_15	1403313.AXBR01000002_gene4201	3.53e-35	135.0	COG0765@1|root,COG0765@2|Bacteria,1TRS7@1239|Firmicutes,4HF5R@91061|Bacilli,1ZE92@1386|Bacillus	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	occM3	-	-	ko:K16959	ko02010,map02010	M00585	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.13	-	-	BPD_transp_1
HKD3_k127_6392922_10	1340434.AXVA01000008_gene3567	1.621e-112	367.0	COG0765@1|root,COG0765@2|Bacteria,1TY31@1239|Firmicutes,4HF3T@91061|Bacilli,1ZQ17@1386|Bacillus	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K16958	ko02010,map02010	M00585	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.13	-	-	BPD_transp_1
HKD3_k127_6392922_7	1403313.AXBR01000002_gene4203	1.004e-138	444.0	COG0834@1|root,COG0834@2|Bacteria,1UKNE@1239|Firmicutes,4HD8M@91061|Bacilli,1ZEZI@1386|Bacillus	91061|Bacilli	ET	Bacterial periplasmic substrate-binding proteins	tcyK	-	-	ko:K16957	ko02010,map02010	M00585	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.13	-	-	SBP_bac_3
HKD3_k127_6392922_14	1340434.AXVA01000008_gene3565	5.991e-38	143.0	COG0695@1|root,COG0695@2|Bacteria,1VFJ0@1239|Firmicutes,4HKXP@91061|Bacilli,1ZHVX@1386|Bacillus	91061|Bacilli	O	COG0695 Glutaredoxin and related proteins	ytnI	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
HKD3_k127_6392922_2	1403313.AXBR01000002_gene4206	5.401e-241	749.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	ytnJ	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_6392922_4	997296.PB1_05055	2.734e-181	572.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZB5H@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_6392922_0	1033734.CAET01000001_gene3937	6.4e-313	970.0	COG1123@1|root,COG4172@2|Bacteria,1UZK8@1239|Firmicutes,4HTUD@91061|Bacilli,1ZSDT@1386|Bacillus	91061|Bacilli	P	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HKD3_k127_6392922_9	1033734.CAET01000001_gene3936	1.696e-130	422.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZC1H@1386|Bacillus	91061|Bacilli	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HKD3_k127_6392922_8	1449063.JMLS01000011_gene273	4.924e-134	433.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,26RTC@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD3_k127_6392922_1	1395587.P364_0123215	1.6e-256	800.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD3_k127_6392922_5	1340434.AXVA01000008_gene3562	1.663e-160	511.0	COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	ytmO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_6392922_13	666686.B1NLA3E_08875	4.671e-40	151.0	COG0196@1|root,COG0196@2|Bacteria,1U8V1@1239|Firmicutes,4IITF@91061|Bacilli,1ZJM2@1386|Bacillus	91061|Bacilli	H	riboflavin kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6392922_6	1340434.AXVA01000008_gene3560	5.525e-142	456.0	COG0583@1|root,COG0583@2|Bacteria,1UXY9@1239|Firmicutes,4HEXP@91061|Bacilli,1ZB03@1386|Bacillus	91061|Bacilli	K	COG0583 Transcriptional regulator	lysR1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_6392922_3	279010.BL01996	6.443e-206	646.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	yjlD	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iYO844.BSU12290	Pyr_redox_2
HKD3_k127_6392922_12	1169144.KB910976_gene780	3.316e-60	211.0	COG2427@1|root,32RCT@2|Bacteria,1V3KC@1239|Firmicutes,4HI44@91061|Bacilli,1ZGD0@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
HKD3_k127_6392922_11	1117379.BABA_18367	1.47e-105	346.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,4HK76@91061|Bacilli,1ZQDT@1386|Bacillus	91061|Bacilli	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HKD3_k127_6394821_3	935836.JAEL01000067_gene1708	3.926e-23	100.0	2EIRB@1|root,33CGR@2|Bacteria,1VFHX@1239|Firmicutes,4HP39@91061|Bacilli,1ZJ0H@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6394821_0	1169144.KB910993_gene2160	1.501e-120	391.0	COG0726@1|root,COG0726@2|Bacteria,1UZQS@1239|Firmicutes,4IPKY@91061|Bacilli,1ZRC8@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	pdaB	GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD3_k127_6394821_2	315749.Bcer98_0143	3.938e-73	252.0	COG2194@1|root,COG2194@2|Bacteria,1UZ64@1239|Firmicutes,4HFDE@91061|Bacilli,1ZFN5@1386|Bacillus	91061|Bacilli	S	Involved in the activation of the KinB signaling pathway of sporulation	kbaA	GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K06349	-	-	-	-	ko00000	-	-	-	KbaA
HKD3_k127_6394821_1	1169144.KB910993_gene2162	1.703e-73	252.0	29HQ2@1|root,304MB@2|Bacteria,1V21Z@1239|Firmicutes,4HG8B@91061|Bacilli,1ZC8S@1386|Bacillus	91061|Bacilli	S	Spore gernimation protein	gerD	-	-	ko:K06294	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_6397114_10	1169144.KB910981_gene3523	1.155e-07	56.0	29SUV@1|root,30E10@2|Bacteria,1UBZT@1239|Firmicutes,4INFP@91061|Bacilli,1ZNER@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6397114_4	260799.BAS3560	2.496e-139	449.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HKD3_k127_6397114_7	1396.DJ87_1217	4.203e-39	146.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4HNN2@91061|Bacilli,1ZHYZ@1386|Bacillus	91061|Bacilli	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
HKD3_k127_6397114_5	574376.BAMA_12330	1.293e-124	407.0	COG0582@1|root,COG0582@2|Bacteria,1V3XQ@1239|Firmicutes,4HI9U@91061|Bacilli,1ZF16@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
HKD3_k127_6397114_3	1405.DJ92_687	6.585e-163	517.0	COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZBII@1386|Bacillus	91061|Bacilli	O	stage V sporulation protein K	spoVK	-	-	ko:K06413	-	-	-	-	ko00000	-	-	-	AAA
HKD3_k127_6397114_11	1405.DJ92_686	0.0009726	42.0	29TIE@1|root,30ERR@2|Bacteria,1UCW1@1239|Firmicutes,4IPC1@91061|Bacilli,1ZPPP@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6397114_2	1169144.KB910981_gene3512	6.253e-185	586.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus	91061|Bacilli	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD3_k127_6397114_1	315749.Bcer98_2383	4.036e-234	728.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus	91061|Bacilli	P	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
HKD3_k127_6397114_6	315749.Bcer98_2382	2.023e-50	182.0	COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,1ZH1F@1386|Bacillus	91061|Bacilli	K	transcriptional	glnR	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141	-	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	MerR_1
HKD3_k127_6397114_0	1405.DJ92_680	2.868e-269	833.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,1ZBIQ@1386|Bacillus	91061|Bacilli	E	glutamine synthetase	glnA	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD3_k127_6397114_8	358681.BBR47_33420	4.073e-31	123.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HEI7@91061|Bacilli,26VNW@186822|Paenibacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HKD3_k127_6397114_9	1460635.JCM19038_2765	4.341e-09	57.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HEI7@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HKD3_k127_6412031_1	574376.BAMA_12640	1.179e-212	666.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HKD3_k127_6412031_0	1169144.KB910926_gene1101	0.0	1110.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,1ZB67@1386|Bacillus	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD3_k127_6412031_6	198094.BA_5732	2.006e-124	401.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,1ZAWG@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HKD3_k127_6412031_4	1405.DJ92_2576	3.393e-132	427.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,1ZCDV@1386|Bacillus	91061|Bacilli	D	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD3_k127_6412031_3	1169144.KB910926_gene1104	4.913e-142	453.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus	91061|Bacilli	D	COG1192 ATPases involved in chromosome partitioning	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD3_k127_6412031_7	218284.CCDN010000007_gene3801	4.234e-105	347.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,1ZBDT@1386|Bacillus	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
HKD3_k127_6412031_8	1169144.KB910926_gene1106	3.765e-71	246.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,4HH5B@91061|Bacilli,1ZCER@1386|Bacillus	91061|Bacilli	S	Sporulation protein YyaC	yyaC	-	-	-	-	-	-	-	-	-	-	-	DUF1256
HKD3_k127_6412031_5	1169144.KB910926_gene1107	2.072e-127	413.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus	91061|Bacilli	M	Mechanosensitive ion channel	ykuT	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HKD3_k127_6412031_9	1131730.BAVI_23759	5.741e-33	128.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,1ZIUV@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yyzM	-	-	-	-	-	-	-	-	-	-	-	DUF951
HKD3_k127_6412031_2	1405.DJ92_2570	8.768e-208	649.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HKD3_k127_6452134_0	1396.DJ87_3752	8.264e-112	368.0	COG0451@1|root,COG0451@2|Bacteria,1V4RV@1239|Firmicutes,4HH8E@91061|Bacilli,1ZNBS@1386|Bacillus	91061|Bacilli	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6452134_1	1396.DJ87_3751	7.237e-80	276.0	2AFIN@1|root,30VZ3@2|Bacteria,1U9TK@1239|Firmicutes,4IK0Z@91061|Bacilli,1ZNQ4@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6464462_0	1405.DJ92_4069	1.015e-98	325.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus	91061|Bacilli	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD3_k127_6464462_3	926556.Echvi_3344	7.139e-08	61.0	COG1335@1|root,COG1335@2|Bacteria,4NP6D@976|Bacteroidetes	976|Bacteroidetes	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HKD3_k127_6464462_2	198094.BA_1439	3.528e-12	67.0	COG5583@1|root,COG5583@2|Bacteria,1UB7K@1239|Firmicutes,4IMKB@91061|Bacilli,1ZKC5@1386|Bacillus	91061|Bacilli	S	Uncharacterized small protein (DUF2292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2292
HKD3_k127_6464462_1	315749.Bcer98_1143	2.797e-18	84.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,1ZCBJ@1386|Bacillus	91061|Bacilli	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15570	PAPS_reduct
HKD3_k127_6501521_0	198467.NP92_08360	0.0	1273.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,4HBRF@91061|Bacilli,21WU1@150247|Anoxybacillus	91061|Bacilli	O	Collagenase	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
HKD3_k127_6501521_21	1118054.CAGW01000017_gene4489	9.603e-19	87.0	2EJ9Z@1|root,33D14@2|Bacteria,1VN43@1239|Firmicutes,4HRPB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6501521_11	358681.BBR47_22060	6.288e-71	244.0	COG3663@1|root,COG3663@2|Bacteria,1V3X9@1239|Firmicutes,4HHMZ@91061|Bacilli	91061|Bacilli	L	COG3663 G T U mismatch-specific DNA glycosylase	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HKD3_k127_6501521_15	1347087.CBYO010000004_gene331	3.165e-50	181.0	COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli	91061|Bacilli	S	Thiol-disulfide oxidoreductase	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
HKD3_k127_6501521_9	574376.BAMA_21155	1.763e-96	322.0	28PJY@1|root,2ZC9F@2|Bacteria,1V390@1239|Firmicutes,4HG7F@91061|Bacilli,1ZDN7@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1836)	ykrK	-	-	-	-	-	-	-	-	-	-	-	DUF1836
HKD3_k127_6501521_18	574375.BAGA_13960	1.026e-38	146.0	2DTR5@1|root,33MCD@2|Bacteria,1VH2H@1239|Firmicutes,4HQ9N@91061|Bacilli,1ZI67@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2653)	yxcD	-	-	-	-	-	-	-	-	-	-	-	DUF2653
HKD3_k127_6501521_12	1280390.CBQR020000004_gene60	2.463e-68	237.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,26RMK@186822|Paenibacillaceae	91061|Bacilli	I	acyl-CoA thioester hydrolase	ykhA	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_6501521_16	1461580.CCAS010000013_gene1680	1.31e-43	167.0	COG5395@1|root,COG5395@2|Bacteria,1V515@1239|Firmicutes,4HHT3@91061|Bacilli,1ZHR0@1386|Bacillus	91061|Bacilli	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
HKD3_k127_6501521_13	1449063.JMLS01000012_gene5468	5.362e-68	238.0	2DN86@1|root,32W1X@2|Bacteria,1VA8R@1239|Firmicutes,4HN75@91061|Bacilli,26VAJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6501521_1	1405.DJ92_387	3.792e-240	771.0	COG0699@1|root,COG4783@1|root,COG0699@2|Bacteria,COG4783@2|Bacteria,1UHR6@1239|Firmicutes,4I1K3@91061|Bacilli,1ZS13@1386|Bacillus	91061|Bacilli	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,TPR_8
HKD3_k127_6501521_8	1169144.KB910950_gene3245	6.876e-124	404.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yitS	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD3_k127_6501521_3	1307436.PBF_15459	5.003e-195	624.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_9
HKD3_k127_6501521_4	315749.Bcer98_2014	1.014e-191	602.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,1ZB0X@1386|Bacillus	91061|Bacilli	E	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate	aroA	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD3_k127_6501521_2	315730.BcerKBAB4_1440	3.103e-205	643.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,1ZB2N@1386|Bacillus	91061|Bacilli	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HKD3_k127_6501521_7	1169144.KB910961_gene4062	8.98e-150	481.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus	91061|Bacilli	E	prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22610	ACT,PDH
HKD3_k127_6501521_5	315730.BcerKBAB4_2747	2.915e-191	605.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HKD3_k127_6501521_14	1235279.C772_01771	1.387e-56	211.0	COG3180@1|root,COG3180@2|Bacteria,1UVXN@1239|Firmicutes,4HDRW@91061|Bacilli,26F32@186818|Planococcaceae	91061|Bacilli	S	Transition state regulatory protein AbrB	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
HKD3_k127_6501521_6	665952.HMPREF1015_03128	6.478e-152	490.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus	91061|Bacilli	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD3_k127_6501521_17	1348908.KI518611_gene3371	1.205e-42	160.0	COG1846@1|root,COG1846@2|Bacteria,1VBQ1@1239|Firmicutes,4HMXC@91061|Bacilli,1ZIKI@1386|Bacillus	91061|Bacilli	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HKD3_k127_6501521_10	796606.BMMGA3_08765	3.657e-79	269.0	COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli,1ZB2X@1386|Bacillus	91061|Bacilli	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	XK27_06885	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_6501521_20	1211814.CAPG01000003_gene52	1.002e-21	96.0	2DXX6@1|root,3471T@2|Bacteria,1UMEC@1239|Firmicutes,4ITVD@91061|Bacilli,1ZND2@1386|Bacillus	91061|Bacilli	S	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F
HKD3_k127_6503635_12	574375.BAGA_11150	5.75e-62	217.0	COG1136@1|root,COG1136@2|Bacteria,1V3HH@1239|Firmicutes,4HHE3@91061|Bacilli,1ZE0V@1386|Bacillus	91061|Bacilli	V	ABC transporter	-	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HKD3_k127_6503635_3	574375.BAGA_11145	1.122e-193	608.0	COG1252@1|root,COG1252@2|Bacteria,1TPE6@1239|Firmicutes,4H9MY@91061|Bacilli,1ZC0V@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	yutJ	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD3_k127_6503635_18	1169144.KB911026_gene2982	2.004e-35	136.0	COG4844@1|root,COG4844@2|Bacteria,1VFJJ@1239|Firmicutes,4HNQ8@91061|Bacilli,1ZHVJ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0349 family	yuzB	-	-	-	-	-	-	-	-	-	-	-	DUF1450
HKD3_k127_6503635_8	1169144.KB911004_gene2319	1.033e-135	436.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,1ZD98@1386|Bacillus	91061|Bacilli	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD3_k127_6503635_15	574375.BAGA_11120	4.542e-51	183.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,1ZH92@1386|Bacillus	91061|Bacilli	S	Belongs to the HesB IscA family	yutM	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD3_k127_6503635_16	218284.CCDN010000004_gene3138	1.411e-43	169.0	COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,1ZCH3@1386|Bacillus	91061|Bacilli	ET	Belongs to the bacterial solute-binding protein 3 family	tcyA	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
HKD3_k127_6503635_11	1121342.AUCO01000004_gene715	3.081e-65	244.0	COG5617@1|root,COG5617@2|Bacteria,1V776@1239|Firmicutes,24J3S@186801|Clostridia,36JSM@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
HKD3_k127_6503635_19	1120973.AQXL01000100_gene1129	1.473e-23	113.0	COG5542@1|root,COG5542@2|Bacteria,1V7KR@1239|Firmicutes,4HQF2@91061|Bacilli,279J3@186823|Alicyclobacillaceae	91061|Bacilli	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
HKD3_k127_6503635_6	315749.Bcer98_3541	1.231e-172	550.0	COG0477@1|root,COG2814@2|Bacteria,1TRH2@1239|Firmicutes,4HF7T@91061|Bacilli,1ZS2V@1386|Bacillus	91061|Bacilli	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD3_k127_6503635_5	1405.DJ92_2016	2.567e-179	566.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1ZCEZ@1386|Bacillus	91061|Bacilli	C	reductase	yumC	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	iYO844.BSU32110	Pyr_redox_2
HKD3_k127_6503635_2	574375.BAGA_10980	1.121e-212	665.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	yumB	GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iYO844.BSU32100	Pyr_redox_2
HKD3_k127_6503635_10	1169144.KB910991_gene2729	1.835e-68	236.0	COG1051@1|root,COG1051@2|Bacteria,1V4TX@1239|Firmicutes,4HH70@91061|Bacilli,1ZGXJ@1386|Bacillus	91061|Bacilli	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_6503635_17	315749.Bcer98_3535	2.964e-37	143.0	2CDZ2@1|root,32RYS@2|Bacteria,1VABM@1239|Firmicutes,4HKKB@91061|Bacilli,1ZHT7@1386|Bacillus	91061|Bacilli	S	Putative membrane protein	yuiB	-	-	-	-	-	-	-	-	-	-	-	YuiB
HKD3_k127_6503635_9	315749.Bcer98_3534	2.719e-73	253.0	COG3584@1|root,COG3584@2|Bacteria,1UYMN@1239|Firmicutes,4HIVQ@91061|Bacilli,1ZDD1@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuiC	-	-	-	-	-	-	-	-	-	-	-	3D
HKD3_k127_6503635_13	1307436.PBF_19268	1.548e-57	202.0	COG1547@1|root,COG1547@2|Bacteria,1V9RH@1239|Firmicutes,4HJA4@91061|Bacilli,1ZGEY@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
HKD3_k127_6503635_1	315749.Bcer98_3532	3.358e-238	744.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus	91061|Bacilli	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HKD3_k127_6503635_7	315749.Bcer98_3529	2.698e-166	526.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	gtaB	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD3_k127_6503635_4	1169144.KB910966_gene3449	1.577e-181	571.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,1ZD2D@1386|Bacillus	91061|Bacilli	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	csbB	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
HKD3_k127_6503635_14	1169144.KB910966_gene3448	1.629e-53	191.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,1ZG2Y@1386|Bacillus	91061|Bacilli	S	GtrA-like protein	gtcA	-	-	-	-	-	-	-	-	-	-	-	GtrA
HKD3_k127_6503635_0	1169144.KB910966_gene3447	3.921e-278	868.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,1ZQ44@1386|Bacillus	91061|Bacilli	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD3_k127_6517098_12	1396.DJ87_5605	1.228e-59	213.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus	91061|Bacilli	E	Orn Lys Arg decarboxylase	yaaO	-	-	-	-	-	-	-	-	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD3_k127_6517098_9	315730.BcerKBAB4_0025	9.315e-87	292.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,1ZBSZ@1386|Bacillus	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
HKD3_k127_6517098_2	1169144.KB910956_gene4141	7.264e-148	473.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,1ZBDA@1386|Bacillus	91061|Bacilli	L	DNA polymerase III	holB	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
HKD3_k127_6517098_1	1169144.KB910956_gene4140	5.497e-153	487.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli,1ZBCK@1386|Bacillus	91061|Bacilli	S	stage 0 sporulation protein	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	PSP1
HKD3_k127_6517098_11	260799.BAS0032	1.854e-60	210.0	COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,1ZGZH@1386|Bacillus	91061|Bacilli	L	Involved in initiation control of chromosome replication	yabA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	YabB
HKD3_k127_6517098_6	315749.Bcer98_0029	7.729e-134	430.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus	91061|Bacilli	S	Conserved hypothetical protein 95	yabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.223	ko:K07461,ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GIY-YIG,MTS
HKD3_k127_6517098_16	1196029.ALIM01000036_gene1069	3.104e-28	116.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,1ZIXI@1386|Bacillus	91061|Bacilli	L	endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD3_k127_6517098_5	574375.BAGA_22210	1.751e-139	448.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus	91061|Bacilli	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD3_k127_6517098_13	1169144.KB910956_gene4135	1.087e-46	169.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,1ZH0F@1386|Bacillus	91061|Bacilli	K	COG2002 Regulators of stationary sporulation gene expression	abrB	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
HKD3_k127_6517098_0	1169144.KB910956_gene4134	0.0	1131.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD3_k127_6517098_7	574376.BAMA_12025	6.307e-132	424.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus	91061|Bacilli	L	hydrolase, TatD	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HKD3_k127_6517098_8	574376.BAMA_12030	1.73e-123	407.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus	91061|Bacilli	T	protein conserved in bacteria	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
HKD3_k127_6517098_10	574375.BAGA_22235	4.432e-81	273.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,1ZFNN@1386|Bacillus	91061|Bacilli	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
HKD3_k127_6517098_3	315749.Bcer98_0036	2.234e-147	471.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1ZBZX@1386|Bacillus	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HKD3_k127_6517098_4	574375.BAGA_22245	2.307e-140	450.0	28HCB@1|root,2Z7P7@2|Bacteria,1TNZK@1239|Firmicutes,4HBET@91061|Bacilli,1ZCTC@1386|Bacillus	91061|Bacilli	S	peptidase	yabG	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0043591,GO:0043593,GO:0044426,GO:0044462,GO:0044464,GO:0071944	-	ko:K06436	-	-	-	-	ko00000	-	-	-	Peptidase_U57
HKD3_k127_6517098_14	1034347.CAHJ01000087_gene1734	3.047e-33	129.0	COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,1ZI19@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	veg	-	-	-	-	-	-	-	-	-	-	-	VEG
HKD3_k127_6517098_17	1405.DJ92_2635	6.085e-23	99.0	2E2ZT@1|root,32Y0E@2|Bacteria,1VEHE@1239|Firmicutes,4HNK8@91061|Bacilli,1ZITS@1386|Bacillus	91061|Bacilli	S	DNA topological change	sspF	-	-	ko:K06423	-	-	-	-	ko00000	-	-	-	SASP
HKD3_k127_6517098_15	574375.BAGA_22260	1.856e-29	117.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,1ZAYT@1386|Bacillus	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_6521818_5	1169144.KB910999_gene3109	4.428e-41	154.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,1ZI02@1386|Bacillus	91061|Bacilli	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iYO844.BSU04620	ACPS
HKD3_k127_6521818_1	315730.BcerKBAB4_0229	1.18e-142	459.0	COG2834@1|root,COG2834@2|Bacteria,1TSRE@1239|Firmicutes,4HBCH@91061|Bacilli,1ZBE6@1386|Bacillus	91061|Bacilli	M	COG2834 Outer membrane lipoprotein-sorting protein	ydcC	-	-	-	-	-	-	-	-	-	-	-	DUF4367
HKD3_k127_6521818_0	1396.DJ87_5106	9.478e-156	501.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus	91061|Bacilli	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.5	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HKD3_k127_6521818_4	1169144.KB910999_gene3113	1.259e-43	160.0	COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,4HKPU@91061|Bacilli,1ZGYI@1386|Bacillus	91061|Bacilli	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain	ndoAI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
HKD3_k127_6521818_3	1405.DJ92_2848	4.115e-66	226.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,1ZG8R@1386|Bacillus	91061|Bacilli	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HKD3_k127_6521818_2	1396.DJ87_5103	6.022e-103	341.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus	91061|Bacilli	K	COG2183 Transcriptional accessory protein	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HKD3_k127_6531367_4	279808.SH2165	6.812e-26	107.0	COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli,4GXTK@90964|Staphylococcaceae	91061|Bacilli	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
HKD3_k127_6531367_2	315749.Bcer98_1066	2.225e-113	369.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli,1ZBRU@1386|Bacillus	91061|Bacilli	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
HKD3_k127_6531367_3	574375.BAGA_07750	4.785e-82	275.0	COG0720@1|root,COG0720@2|Bacteria,1V206@1239|Firmicutes,4HG4R@91061|Bacilli,1ZRSR@1386|Bacillus	91061|Bacilli	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD3_k127_6531367_1	1405.DJ92_3982	1.016e-129	417.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli,1ZCJD@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
HKD3_k127_6531367_0	315730.BcerKBAB4_1255	2.766e-150	486.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus	91061|Bacilli	T	Histidine kinase	kinB	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA
HKD3_k127_6531367_5	574376.BAMA_13230	6.473e-08	55.0	29TB4@1|root,30EI5@2|Bacteria,1UCKC@1239|Firmicutes,4IP2G@91061|Bacilli,1ZPA4@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6541231_4	1121091.AUMP01000067_gene1555	6.731e-53	188.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HD93@91061|Bacilli	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_6541231_0	1121091.AUMP01000067_gene1556	3.152e-118	394.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,4ISRX@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD3_k127_6541231_2	315730.BcerKBAB4_0842	9.903e-66	231.0	COG1842@1|root,COG1842@2|Bacteria,1V2MH@1239|Firmicutes,4IRMA@91061|Bacilli	91061|Bacilli	KT	Phage shock protein A	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
HKD3_k127_6541231_3	1123252.ATZF01000001_gene1055	1.781e-65	230.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,27CEM@186824|Thermoactinomycetaceae	91061|Bacilli	I	Acid phosphatase homologues	pap2c	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_6541231_1	574375.BAGA_07880	4.856e-83	289.0	COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,1ZD6Q@1386|Bacillus	91061|Bacilli	M	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)	dltD	-	-	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	DltD
HKD3_k127_65468_3	1122915.AUGY01000174_gene4169	3.137e-54	196.0	2BRBH@1|root,32KA2@2|Bacteria,1U1VU@1239|Firmicutes,4IBC7@91061|Bacilli,2741E@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_65468_5	485913.Krac_5451	4.863e-27	113.0	2DQ3G@1|root,334K8@2|Bacteria,2G77Z@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2568
HKD3_k127_65468_2	1118054.CAGW01000060_gene2570	2.682e-83	295.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,26RNQ@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	hlyD3	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD3_k127_65468_1	1118054.CAGW01000060_gene2571	4.896e-100	334.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,26R6I@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_65468_0	1157490.EL26_00035	2.178e-150	485.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,2795F@186823|Alicyclobacillaceae	91061|Bacilli	V	MacB-like periplasmic core domain	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_65468_6	796606.BMMGA3_13920	1.355e-05	48.0	28V6V@1|root,2ZHA0@2|Bacteria,1W46A@1239|Firmicutes,4I0GX@91061|Bacilli,1ZK0H@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_65468_4	1120971.AUCA01000019_gene1142	1.738e-49	183.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HCVX@91061|Bacilli,279VQ@186823|Alicyclobacillaceae	91061|Bacilli	S	Glyco_18	Chia	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Glyco_hydro_18,SH3_3,SH3_4
HKD3_k127_6620001_4	315749.Bcer98_0588	8.232e-10	61.0	COG3125@1|root,COG3125@2|Bacteria,1VFT1@1239|Firmicutes,4HQ12@91061|Bacilli	91061|Bacilli	C	quinol oxidase, subunit	qoxD	GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.10.3.12	ko:K02829	ko00190,ko01100,map00190,map01100	M00416	R09492	RC00819	ko00000,ko00001,ko00002,ko01000	-	-	-	COX4_pro
HKD3_k127_6620001_2	1169144.KB910945_gene2472	9.131e-97	319.0	COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HCWH@91061|Bacilli,1ZDEX@1386|Bacillus	91061|Bacilli	C	quinol oxidase, subunit	qoxC	GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.10.3.12	ko:K02828	ko00190,ko01100,map00190,map01100	M00416	R09492	RC00819	ko00000,ko00001,ko00002,ko01000	-	-	-	COX3
HKD3_k127_6620001_0	260799.BAS0668	0.0	1117.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus	91061|Bacilli	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	qoxB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.10.3.12	ko:K02827	ko00190,ko01100,map00190,map01100	M00416	R09492	RC00819	ko00000,ko00001,ko00002,ko01000	3.D.4.1	-	-	COX1
HKD3_k127_6620001_1	198094.BA_0703	1.58e-143	460.0	COG1622@1|root,COG1622@2|Bacteria,1TPF6@1239|Firmicutes,4HA9J@91061|Bacilli,1ZB28@1386|Bacillus	91061|Bacilli	C	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I	qoxA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600	1.10.3.12	ko:K02826	ko00190,ko01100,map00190,map01100	M00416	R09492	RC00819	ko00000,ko00001,ko00002,ko01000	3.D.4.1	-	iSB619.SA_RS05175	COX2,COX2_TM
HKD3_k127_6620001_6	1449063.JMLS01000008_gene4919	0.0003132	49.0	2ETPN@1|root,33M7B@2|Bacteria,1VK64@1239|Firmicutes,4IDKS@91061|Bacilli,270QM@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6620001_3	1408254.T458_09835	8.035e-90	301.0	COG0745@1|root,COG0745@2|Bacteria,1UX1V@1239|Firmicutes,4HD2J@91061|Bacilli,26SDK@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_6620001_5	1246484.D479_05545	2.788e-08	62.0	COG0642@1|root,COG2205@2|Bacteria,1TZXJ@1239|Firmicutes,4HDAI@91061|Bacilli,3NFR7@45667|Halobacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	phoR_2	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD3_k127_6624836_1	1405.DJ92_1373	2.723e-158	501.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	iSB619.SA_RS06920	ABC_tran
HKD3_k127_6624836_4	1396.DJ87_596	2.72e-96	319.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,1ZDDZ@1386|Bacillus	91061|Bacilli	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HKD3_k127_6624836_2	574376.BAMA_22295	7.121e-145	469.0	COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,4ISUZ@91061|Bacilli,1ZD41@1386|Bacillus	91061|Bacilli	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
HKD3_k127_6624836_0	1169144.KB910968_gene3359	2.377e-284	894.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,4IS8X@91061|Bacilli,1ZDK6@1386|Bacillus	91061|Bacilli	GJM	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I
HKD3_k127_6624836_8	1227360.C176_14817	6.681e-23	98.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,26G36@186818|Planococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD3_k127_6624836_7	1405.DJ92_1369	7.116e-59	210.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,1ZH1W@1386|Bacillus	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HKD3_k127_6624836_5	1267580.AF6_0879	2.216e-89	308.0	COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,21V7J@150247|Anoxybacillus	91061|Bacilli	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
HKD3_k127_6624836_9	260799.BAS4166	1.257e-18	87.0	COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,1ZISV@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yqgQ	-	-	-	-	-	-	-	-	-	-	-	DUF910
HKD3_k127_6624836_3	1169144.KB910968_gene3355	4.461e-134	434.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,1ZBV8@1386|Bacillus	91061|Bacilli	G	Glucokinase	glcK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07790	ROK
HKD3_k127_6624836_10	1423321.AS29_00225	5.062e-13	70.0	2ES0W@1|root,306VH@2|Bacteria,1VET3@1239|Firmicutes,4I9TK@91061|Bacilli,1ZK2C@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2759)	yqgW	-	-	-	-	-	-	-	-	-	-	-	DUF2759
HKD3_k127_6624836_6	1405.DJ92_1365	5.209e-86	287.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqgX	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HKD3_k127_6651103_5	666686.B1NLA3E_07880	2.228e-13	70.0	29S96@1|root,30DDQ@2|Bacteria,1UB6D@1239|Firmicutes,4IMJ1@91061|Bacilli,1ZK9M@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6651103_0	1169144.KB910934_gene4333	4.527e-252	794.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4H9MT@91061|Bacilli,1ZAX9@1386|Bacillus	91061|Bacilli	M	Penicillin-binding Protein	pbpC	-	3.4.16.4	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	M00625	-	-	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	MecA_N,PBP_dimer,Transpeptidase
HKD3_k127_6651103_1	1295642.H839_15542	2.588e-92	305.0	COG0492@1|root,COG0492@2|Bacteria,1UXYT@1239|Firmicutes,4HDB8@91061|Bacilli,1WERQ@129337|Geobacillus	91061|Bacilli	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
HKD3_k127_6651103_3	224308.BSU21440	1.868e-22	102.0	COG1495@1|root,COG1495@2|Bacteria	2|Bacteria	O	protein disulfide oxidoreductase activity	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
HKD3_k127_6651103_4	935836.JAEL01000077_gene171	1.906e-15	79.0	2EIIR@1|root,33CA1@2|Bacteria,1VMUM@1239|Firmicutes,4HSC6@91061|Bacilli,1ZJ19@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6651103_2	666686.B1NLA3E_11345	6.329e-29	117.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HCZ7@91061|Bacilli,1ZCB1@1386|Bacillus	91061|Bacilli	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
HKD3_k127_66652_1	574376.BAMA_17425	0.0	1009.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus	91061|Bacilli	E	oligoendopeptidase F	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD3_k127_66652_14	1169144.KB910927_gene1331	1.573e-93	320.0	COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1ZCFD@1386|Bacillus	91061|Bacilli	S	Competence protein	coiA	-	-	ko:K06198	-	-	-	-	ko00000	-	-	-	CoiA
HKD3_k127_66652_4	1297581.H919_03377	1.186e-198	631.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,21WT1@150247|Anoxybacillus	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HKD3_k127_66652_12	315749.Bcer98_0906	1.309e-101	334.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HDV3@91061|Bacilli,1ZAV4@1386|Bacillus	91061|Bacilli	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC	mecA	GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
HKD3_k127_66652_17	574375.BAGA_21250	8.523e-75	257.0	COG0861@1|root,COG0861@2|Bacteria,1V26T@1239|Firmicutes,4HGSV@91061|Bacilli,1ZQM7@1386|Bacillus	91061|Bacilli	P	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TerC
HKD3_k127_66652_18	1169144.KB910927_gene1335	6.308e-74	250.0	COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZFK4@1386|Bacillus	91061|Bacilli	K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress	spxA	-	-	ko:K16509	-	-	-	-	ko00000	-	-	-	ArsC
HKD3_k127_66652_22	1169144.KB910927_gene1336	4.457e-21	93.0	2EAWM@1|root,334XV@2|Bacteria,1VJNN@1239|Firmicutes,4IFAK@91061|Bacilli,1ZIVM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_66652_8	1295642.H839_03061	7.647e-160	507.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1WEDJ@129337|Geobacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD3_k127_66652_3	574376.BAMA_17375	9.297e-200	625.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD3_k127_66652_6	574375.BAGA_21310	2.078e-170	540.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus	91061|Bacilli	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
HKD3_k127_66652_9	491915.Aflv_2132	1.337e-150	481.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,21WS6@150247|Anoxybacillus	91061|Bacilli	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
HKD3_k127_66652_21	1405.DJ92_3796	6.447e-24	105.0	2EV5B@1|root,33NK5@2|Bacteria,1VQDN@1239|Firmicutes,4HS8R@91061|Bacilli,1ZKSA@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF3899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3899
HKD3_k127_66652_5	574376.BAMA_17355	6.344e-181	569.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,1ZCUY@1386|Bacillus	91061|Bacilli	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HKD3_k127_66652_10	1405.DJ92_3794	1.626e-133	428.0	28IPR@1|root,2Z8PJ@2|Bacteria,1TPYR@1239|Firmicutes,4HBI7@91061|Bacilli,1ZAX0@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0736 family	yjbA	-	-	-	-	-	-	-	-	-	-	-	DUF3603
HKD3_k127_66652_16	1405.DJ92_3793	9.309e-79	271.0	COG5504@1|root,COG5504@2|Bacteria,1W1FI@1239|Firmicutes,4HYXE@91061|Bacilli,1ZQRF@1386|Bacillus	91061|Bacilli	O	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2268
HKD3_k127_66652_2	315749.Bcer98_0891	1.009e-220	689.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
HKD3_k127_66652_7	1444310.JANV01000043_gene3477	9.455e-164	519.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,1ZAQ1@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU11330	ACP_syn_III,ACP_syn_III_C
HKD3_k127_66652_19	1169144.KB910927_gene1350	6.149e-42	164.0	COG0451@1|root,COG0451@2|Bacteria,1UAVB@1239|Firmicutes,4IM85@91061|Bacilli,1ZJG3@1386|Bacillus	91061|Bacilli	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD3_k127_66652_15	574376.BAMA_17320	1.646e-90	303.0	COG2267@1|root,COG2267@2|Bacteria,1UZM1@1239|Firmicutes,4HFJW@91061|Bacilli,1ZD5F@1386|Bacillus	91061|Bacilli	I	carboxylic ester hydrolase activity	yjaU	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HKD3_k127_66652_24	1169144.KB910927_gene1352	3.42e-13	71.0	2DRQH@1|root,33CMT@2|Bacteria,1VMJ6@1239|Firmicutes,4HR1S@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF2929)	yjzD	-	-	-	-	-	-	-	-	-	-	-	DUF2929
HKD3_k127_66652_0	1169144.KB910927_gene1353	0.0	1347.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus	91061|Bacilli	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HKD3_k127_66652_20	315749.Bcer98_0884	9.122e-29	116.0	2EG5I@1|root,339XF@2|Bacteria,1VN1D@1239|Firmicutes,4HRD8@91061|Bacilli,1ZIX6@1386|Bacillus	91061|Bacilli	S	YjzC-like protein	yjzC	-	-	-	-	-	-	-	-	-	-	-	YjzC
HKD3_k127_66652_11	574375.BAGA_21385	2.852e-121	394.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,1ZC4W@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	yitU	-	3.1.3.104	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3
HKD3_k127_66652_25	1169144.KB910927_gene1356	1.039e-12	68.0	2EESV@1|root,338KD@2|Bacteria,1VFET@1239|Firmicutes,4HP8V@91061|Bacilli,1ZIWM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_66652_23	574376.BAMA_17290	3.949e-18	85.0	2A0JV@1|root,30NQ2@2|Bacteria,1TWUS@1239|Firmicutes,4HS9X@91061|Bacilli,1ZJXW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3813)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3813
HKD3_k127_66652_13	315749.Bcer98_0880	6.578e-101	332.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZDFA@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yitT	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_6670330_2	1345695.CLSA_c26760	3.128e-07	61.0	2DETX@1|root,2ZP8Z@2|Bacteria,1W4UB@1239|Firmicutes,24VW4@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
HKD3_k127_6670330_1	1200557.JHWV01000006_gene1678	1.494e-07	57.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,4H4KD@909932|Negativicutes	909932|Negativicutes	L	RNase H	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
HKD3_k127_6670330_0	1313301.AUGC01000011_gene1149	1.289e-80	271.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
HKD3_k127_669436_14	1089548.KI783301_gene3136	8.94e-48	174.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,3WFI1@539002|Bacillales incertae sedis	91061|Bacilli	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
HKD3_k127_669436_5	1122947.FR7_3710	3.25e-176	564.0	COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H77J@909932|Negativicutes	909932|Negativicutes	E	Amino acid permease	-	-	-	ko:K03293	-	-	-	-	ko00000	2.A.3.1	-	-	AA_permease
HKD3_k127_669436_12	1118054.CAGW01000017_gene4319	7.205e-71	246.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HDVJ@91061|Bacilli,26TUI@186822|Paenibacillaceae	91061|Bacilli	K	haloacid dehalogenase-like hydrolase	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD3_k127_669436_13	441769.ABFU01000024_gene1002	3.935e-61	217.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,1ZEVR@1386|Bacillus	91061|Bacilli	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
HKD3_k127_669436_16	1230342.CTM_07001	3.308e-38	149.0	COG4635@1|root,COG4635@2|Bacteria,1VBP3@1239|Firmicutes,24JC3@186801|Clostridia,36JH5@31979|Clostridiaceae	186801|Clostridia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
HKD3_k127_669436_4	1385514.N782_05730	1.54e-184	591.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,4HIY3@91061|Bacilli,2Y8ZV@289201|Pontibacillus	91061|Bacilli	T	Chemotaxis protein CheY	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD,HD_5
HKD3_k127_669436_6	345219.Bcoa_0942	2.173e-153	498.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4H9N0@91061|Bacilli,1ZQ9M@1386|Bacillus	91061|Bacilli	F	Amidohydrolase family	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
HKD3_k127_669436_2	1123284.KB899055_gene980	3.682e-209	660.0	COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,4HAIM@91061|Bacilli	91061|Bacilli	FH	COG1953 Cytosine uracil thiamine allantoin permeases	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
HKD3_k127_669436_1	1295642.H839_08684	1.655e-210	659.0	COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli,1WG6I@129337|Geobacillus	91061|Bacilli	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_669436_11	1169144.KB910925_gene100	1.118e-73	254.0	COG4708@1|root,COG4708@2|Bacteria,1V463@1239|Firmicutes,4HH0P@91061|Bacilli,1ZFSB@1386|Bacillus	91061|Bacilli	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
HKD3_k127_669436_15	1121019.AUMN01000020_gene1634	6.069e-40	152.0	2CBZ2@1|root,32RUD@2|Bacteria,2IQJC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2871)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
HKD3_k127_669436_8	1196322.A370_03296	3.643e-122	399.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,36E3S@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
HKD3_k127_669436_17	1405.DJ92_2977	4.716e-31	123.0	COG0166@1|root,COG0166@2|Bacteria,1VFQ2@1239|Firmicutes,4HNRS@91061|Bacilli,1ZIWJ@1386|Bacillus	91061|Bacilli	G	Helix-turn-helix domain	yoeD	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HKD3_k127_669436_0	1499680.CCFE01000030_gene3642	4.336e-255	794.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4HAI5@91061|Bacilli,1ZDN1@1386|Bacillus	91061|Bacilli	C	Acetyl-CoA hydrolase/transferase N-terminal domain	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD3_k127_669436_10	1033734.CAET01000065_gene2162	1.439e-95	317.0	COG3279@1|root,COG3279@2|Bacteria,1UGZ1@1239|Firmicutes,4HD88@91061|Bacilli,1ZD1A@1386|Bacillus	91061|Bacilli	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HKD3_k127_669436_3	1295642.H839_01571	2.544e-206	652.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4HAI5@91061|Bacilli,1WE6U@129337|Geobacillus	91061|Bacilli	C	succinate CoA transferase	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD3_k127_669436_9	471223.GWCH70_0414	6.316e-117	398.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1TRH0@1239|Firmicutes,4HBC2@91061|Bacilli,1WHCM@129337|Geobacillus	91061|Bacilli	T	Signal transduction histidine kinase, nitrogen specific, NtrB	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
HKD3_k127_669436_7	315749.Bcer98_0371	6.629e-148	474.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,1ZCIY@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	M1-596	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
HKD3_k127_669436_18	1196029.ALIM01000014_gene2685	3.622e-07	52.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HKD3_k127_669450_1	315749.Bcer98_1221	1.962e-179	568.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,1ZARR@1386|Bacillus	91061|Bacilli	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HKD3_k127_669450_2	1405.DJ92_4146	1.382e-155	497.0	COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,1ZCXC@1386|Bacillus	91061|Bacilli	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
HKD3_k127_669450_7	1243664.CAVL020000008_gene4085	1.516e-12	68.0	2EHPS@1|root,33BFI@2|Bacteria,1VM1E@1239|Firmicutes,4HS3S@91061|Bacilli,1ZK03@1386|Bacillus	91061|Bacilli	S	YpzI-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YpzI
HKD3_k127_669450_6	574375.BAGA_16765	9.708e-20	100.0	2C369@1|root,32TN5@2|Bacteria,1VDHE@1239|Firmicutes,4HN2A@91061|Bacilli,1ZDBJ@1386|Bacillus	91061|Bacilli	-	-	yphA	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_669450_4	1169144.KB910925_gene182	3.267e-133	430.0	28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,4HB3C@91061|Bacilli,1ZBT4@1386|Bacillus	91061|Bacilli	S	YIEGIA protein	yphB	-	-	ko:K05739	-	-	-	-	ko00000	-	-	-	YIEGIA
HKD3_k127_669450_5	1405.DJ92_4152	6.475e-26	107.0	2E5GX@1|root,3308G@2|Bacteria,1VGKE@1239|Firmicutes,4HPSE@91061|Bacilli,1ZIU7@1386|Bacillus	91061|Bacilli	-	-	ypzH	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_669450_0	1169144.KB910925_gene180	1.161e-254	790.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HKD3_k127_669450_3	315749.Bcer98_1228	3.695e-148	473.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus	91061|Bacilli	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD3_k127_6694769_12	574375.BAGA_24125	1.109e-59	209.0	COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,1ZH35@1386|Bacillus	91061|Bacilli	L	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H,RVT_3
HKD3_k127_6694769_10	574376.BAMA_14400	3.527e-81	275.0	COG0328@1|root,COG0328@2|Bacteria,1VW1Q@1239|Firmicutes,4HWRU@91061|Bacilli,1ZQTD@1386|Bacillus	91061|Bacilli	L	RNase H	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
HKD3_k127_6694769_14	315730.BcerKBAB4_1515	2.418e-19	88.0	2E6UK@1|root,331EA@2|Bacteria,1VF2M@1239|Firmicutes,4HPQ1@91061|Bacilli,1ZKC4@1386|Bacillus	91061|Bacilli	S	Zinc-finger	ypeQ	-	-	-	-	-	-	-	-	-	-	-	zf-C2HCIx2C
HKD3_k127_6694769_15	574375.BAGA_24100	1.88e-17	84.0	29S2J@1|root,30D72@2|Bacteria,1UAXW@1239|Firmicutes,4IMAQ@91061|Bacilli,1ZJNM@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2564)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2564
HKD3_k127_6694769_4	1405.DJ92_4248	9.082e-126	406.0	COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HEQ9@91061|Bacilli,1ZDEK@1386|Bacillus	91061|Bacilli	S	YqcI/YcgG family	-	-	-	ko:K09190	-	-	-	-	ko00000	-	-	-	YqcI_YcgG
HKD3_k127_6694769_7	574375.BAGA_23950	5.139e-98	323.0	COG1280@1|root,COG1280@2|Bacteria,1V1Q5@1239|Firmicutes,4HFVQ@91061|Bacilli,1ZEMW@1386|Bacillus	91061|Bacilli	E	Lysine exporter protein LysE YggA	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD3_k127_6694769_16	198094.BA_1632	1.376e-15	79.0	2E6QK@1|root,331AS@2|Bacteria,1VI6M@1239|Firmicutes,4HQ07@91061|Bacilli,1ZK4Q@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6694769_13	1169144.KB910925_gene95	1.096e-35	138.0	COG3162@1|root,COG3162@2|Bacteria,1VAEW@1239|Firmicutes,4HM0S@91061|Bacilli,1ZHX2@1386|Bacillus	91061|Bacilli	S	Protein of unknown function, DUF485	ywcB	-	-	-	-	-	-	-	-	-	-	-	DUF485
HKD3_k127_6694769_1	198094.BA_1635	2.828e-276	855.0	COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,4HCF6@91061|Bacilli,1ZCX7@1386|Bacillus	91061|Bacilli	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
HKD3_k127_6694769_2	1396.DJ87_4484	6.517e-208	656.0	COG0531@1|root,COG0531@2|Bacteria,1TSSB@1239|Firmicutes,4HFI2@91061|Bacilli,1ZQ7F@1386|Bacillus	91061|Bacilli	E	Amino acid permease	-	-	-	ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
HKD3_k127_6694769_11	198094.BA_1692	3.29e-60	219.0	2F82J@1|root,340G0@2|Bacteria,1VXHY@1239|Firmicutes,4HWWC@91061|Bacilli,1ZM01@1386|Bacillus	91061|Bacilli	K	DNA binding domain of the motility gene repressor (MogR)	mogR	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	MogR_DNAbind
HKD3_k127_6694769_18	315730.BcerKBAB4_1606	2.315e-05	47.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1UYX5@1239|Firmicutes,4HF70@91061|Bacilli,1ZD6X@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	ko:K20342,ko:K20391	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3
HKD3_k127_6694769_8	574376.BAMA_05835	1.364e-89	302.0	28NMK@1|root,2ZBN3@2|Bacteria,1TT4K@1239|Firmicutes,4HPRT@91061|Bacilli,1ZR6F@1386|Bacillus	91061|Bacilli	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	amj	-	-	-	-	-	-	-	-	-	-	-	Amj
HKD3_k127_6694769_9	1396.DJ87_2080	7.358e-83	280.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes,4HH96@91061|Bacilli,1ZR48@1386|Bacillus	91061|Bacilli	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD3_k127_6694769_0	649747.HMPREF0083_06136	0.0	1024.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,26QPV@186822|Paenibacillaceae	91061|Bacilli	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
HKD3_k127_6694769_17	666686.B1NLA3E_08840	5.426e-13	70.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_6694769_5	1501230.ET33_16625	2.89e-112	368.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,26TZ6@186822|Paenibacillaceae	91061|Bacilli	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
HKD3_k127_6694769_6	1200792.AKYF01000010_gene2222	9.621e-103	339.0	COG2011@1|root,COG2011@2|Bacteria,1TR59@1239|Firmicutes,4H9NA@91061|Bacilli,26RA9@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type metal ion transport system, permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
HKD3_k127_6694769_3	1501230.ET33_16615	3.225e-137	440.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,26S40@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD3_k127_6706702_5	1340434.AXVA01000008_gene3558	8.489e-49	177.0	2DBAY@1|root,2Z84S@2|Bacteria,1UJ57@1239|Firmicutes,4IT21@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF1835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
HKD3_k127_6706702_1	86416.Clopa_3581	9.721e-125	406.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,36GPS@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HKD3_k127_6706702_2	1347086.CCBA010000025_gene3148	4.395e-105	351.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZDWB@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD3_k127_6706702_3	1131730.BAVI_23103	2.131e-90	310.0	28KI6@1|root,2ZA3G@2|Bacteria,1UYE9@1239|Firmicutes,4HB9Y@91061|Bacilli,1ZF3A@1386|Bacillus	91061|Bacilli	S	Spore germination B3/ GerAC like, C-terminal	gerXC	-	-	-	-	-	-	-	-	-	-	-	Spore_GerAC
HKD3_k127_6706702_0	1117379.BABA_22733	1.172e-166	537.0	COG0697@1|root,COG0697@2|Bacteria,1TSX6@1239|Firmicutes,4HCV4@91061|Bacilli,1ZCUJ@1386|Bacillus	91061|Bacilli	EG	Bacillus/Clostridium GerA spore germination protein	gerXA	-	-	-	-	-	-	-	-	-	-	-	GerA
HKD3_k127_6706702_4	1227360.C176_11444	3.088e-89	306.0	COG0814@1|root,COG0814@2|Bacteria,1UIZI@1239|Firmicutes,4ISYF@91061|Bacilli,26II5@186818|Planococcaceae	91061|Bacilli	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
HKD3_k127_6836300_1	1033734.CAET01000054_gene1437	1.253e-219	688.0	COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus	91061|Bacilli	E	amino acid peptide transporter	dtpT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD3_k127_6836300_4	1280390.CBQR020000004_gene60	8.568e-63	220.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,26RMK@186822|Paenibacillaceae	91061|Bacilli	I	acyl-CoA thioester hydrolase	ykhA	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD3_k127_6836300_5	457570.Nther_0284	4.231e-50	188.0	COG2865@1|root,COG2865@2|Bacteria,1VVYI@1239|Firmicutes,2518F@186801|Clostridia	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
HKD3_k127_6836300_0	332101.JIBU02000022_gene5073	2.921e-249	772.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,36UIP@31979|Clostridiaceae	186801|Clostridia	E	O-acetylhomoserine	mdeA	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD3_k127_6836300_3	997296.PB1_00320	1.475e-104	346.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	FAD_oxidored,FTP,PPC,Peptidase_M4,Peptidase_M4_C,Peptidase_S8,SLH,VCBS
HKD3_k127_6836300_7	997296.PB1_00315	1.805e-37	144.0	2E5FH@1|root,33077@2|Bacteria,1VH1Q@1239|Firmicutes,4HPD5@91061|Bacilli,1ZKWR@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6836300_10	997296.PB1_00320	9.483e-36	138.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	FAD_oxidored,FTP,PPC,Peptidase_M4,Peptidase_M4_C,Peptidase_S8,SLH,VCBS
HKD3_k127_6836300_6	997296.PB1_00335	1.419e-39	149.0	2E9SM@1|root,333YT@2|Bacteria,1VH0N@1239|Firmicutes,4HNSD@91061|Bacilli,1ZJ6F@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6836300_2	997296.PB1_00330	4.1e-196	617.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HDMN@91061|Bacilli,1ZPWM@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_1,TPR_2
HKD3_k127_6836300_11	997296.PB1_00325	2.539e-20	93.0	COG0438@1|root,COG0438@2|Bacteria,1UMR3@1239|Firmicutes,4HDH9@91061|Bacilli	91061|Bacilli	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1,TPR_8
HKD3_k127_6836300_9	997296.PB1_00320	1.548e-36	147.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	FAD_oxidored,FTP,PPC,Peptidase_M4,Peptidase_M4_C,Peptidase_S8,SLH,VCBS
HKD3_k127_6836300_8	997296.PB1_00330	3.371e-37	141.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HDMN@91061|Bacilli,1ZPWM@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_1,TPR_2
HKD3_k127_6853635_0	574375.BAGA_04390	0.0	1130.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HKD3_k127_6853635_1	260799.BAS4471	1.422e-95	316.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,1ZCBZ@1386|Bacillus	91061|Bacilli	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HKD3_k127_6853635_3	1169144.KB910928_gene1985	1.678e-26	109.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,1ZJBX@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HKD3_k127_6853635_2	1033734.CAET01000070_gene2622	7.737e-62	214.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,1ZG75@1386|Bacillus	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD3_k127_6853635_4	1169144.KB910928_gene1983	9.97e-26	107.0	COG4508@1|root,COG4508@2|Bacteria,1VAGF@1239|Firmicutes,4HKQ3@91061|Bacilli,1ZQR5@1386|Bacillus	91061|Bacilli	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
HKD3_k127_687898_2	1403313.AXBR01000013_gene1446	1.646e-43	160.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,1ZBK1@1386|Bacillus	91061|Bacilli	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_687898_0	1403313.AXBR01000013_gene1445	1.426e-190	598.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,1ZB11@1386|Bacillus	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32250	PALP
HKD3_k127_687898_1	1174504.AJTN02000200_gene3550	1.452e-85	286.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZAVJ@1386|Bacillus	91061|Bacilli	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06610	ACT,Homoserine_dh,NAD_binding_3
HKD3_k127_68842_5	574375.BAGA_07870	3.917e-50	185.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,1ZC09@1386|Bacillus	91061|Bacilli	V	proteins, homologs of microcin C7 resistance protein MccF	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD3_k127_68842_4	1396.DJ87_3308	4.698e-119	392.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBXS@1386|Bacillus	91061|Bacilli	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
HKD3_k127_68842_2	1169144.KB910951_gene3284	1.407e-165	529.0	COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,1ZD6Q@1386|Bacillus	91061|Bacilli	M	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)	dltD	-	-	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	DltD
HKD3_k127_68842_6	574375.BAGA_07885	4.745e-37	140.0	COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,1ZJEB@1386|Bacillus	91061|Bacilli	IQ	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	PP-binding
HKD3_k127_68842_1	1121091.AUMP01000021_gene3152	5.451e-173	549.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli	91061|Bacilli	M	Membrane protein involved in D-alanine export	dltB	-	-	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
HKD3_k127_68842_0	1169144.KB910951_gene3281	8.619e-230	720.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus	91061|Bacilli	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	dltA	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_68842_3	574376.BAMA_13365	9.481e-120	390.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus	91061|Bacilli	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_6887660_2	1295642.H839_03841	1.202e-57	201.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,1WEXR@129337|Geobacillus	91061|Bacilli	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	glxR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
HKD3_k127_6887660_0	315749.Bcer98_2734	1.477e-194	614.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus	91061|Bacilli	E	Aminotransferase	mtnE	-	-	ko:K08969	ko00270,ko01100,map00270,map01100	M00034	R07396	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_6887660_1	574376.BAMA_09520	3.232e-114	373.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1ZB5Z@1386|Bacillus	91061|Bacilli	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	mtnU	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HKD3_k127_6887660_7	1396.DJ87_828	2.792e-12	68.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,4HRBW@91061|Bacilli,1ZK1Y@1386|Bacillus	91061|Bacilli	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD3_k127_6887660_3	574375.BAGA_01610	2.049e-57	206.0	29SB6@1|root,30DFP@2|Bacteria,1UB8T@1239|Firmicutes,4IMMI@91061|Bacilli,1ZKFC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_6887660_5	1405.DJ92_1121	6.704e-26	109.0	29FT8@1|root,302QY@2|Bacteria,1U45G@1239|Firmicutes,4IDX9@91061|Bacilli,1ZNDE@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3928)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3928
HKD3_k127_6887660_4	545693.BMQ_1081	1.725e-29	120.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,4HJDZ@91061|Bacilli,1ZGFU@1386|Bacillus	91061|Bacilli	S	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane	yvaZ	GO:0008150,GO:0009636,GO:0042221,GO:0050896	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
HKD3_k127_6935467_1	326427.Cagg_1542	2.245e-125	406.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
HKD3_k127_6935467_0	796606.BMMGA3_06990	6.881e-242	754.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,4HB4D@91061|Bacilli,1ZBSD@1386|Bacillus	91061|Bacilli	G	mannose-1-phosphate guanylyltransferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HKD3_k127_6935467_2	1200792.AKYF01000009_gene2948	2.898e-118	388.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,4HKSK@91061|Bacilli,26QSQ@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_6941548_1	666686.B1NLA3E_08220	1.273e-141	456.0	2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZDF7@1386|Bacillus	91061|Bacilli	S	spore germination	gerKC	-	-	ko:K06297	-	-	-	-	ko00000	-	-	-	Spore_GerAC
HKD3_k127_6941548_0	666686.B1NLA3E_08225	5.154e-182	573.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus	91061|Bacilli	EG	Spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
HKD3_k127_6961663_2	666686.B1NLA3E_07760	2.807e-115	374.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus	91061|Bacilli	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD3_k127_6961663_1	666686.B1NLA3E_07755	3.443e-133	426.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,1ZCXP@1386|Bacillus	91061|Bacilli	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD3_k127_6961663_0	1121091.AUMP01000018_gene954	6.463e-236	737.0	COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli	91061|Bacilli	EG	COG2610 H gluconate symporter and related permeases	yxjC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	GntP_permease
HKD3_k127_7041_3	1131730.BAVI_02254	1.02e-116	380.0	COG1177@1|root,COG1177@2|Bacteria,1V0UU@1239|Firmicutes,4HD56@91061|Bacilli,1ZF0W@1386|Bacillus	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
HKD3_k127_7041_2	1131730.BAVI_02249	7.484e-135	434.0	COG4132@1|root,COG4132@2|Bacteria,1TRF0@1239|Firmicutes,4HCV5@91061|Bacilli,1ZBZQ@1386|Bacillus	91061|Bacilli	P	ABC transporter (permease)	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
HKD3_k127_7041_4	1280390.CBQR020000003_gene47	8.645e-104	344.0	COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,4HD1Y@91061|Bacilli,26UHQ@186822|Paenibacillaceae	91061|Bacilli	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD3_k127_7041_0	1131730.BAVI_02244	1.383e-180	571.0	COG1840@1|root,COG1840@2|Bacteria,1TR2S@1239|Firmicutes,4HC4U@91061|Bacilli,1ZCYV@1386|Bacillus	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
HKD3_k127_7041_8	240292.Ava_1214	7.723e-37	146.0	COG0431@1|root,COG0431@2|Bacteria,1G651@1117|Cyanobacteria,1HMSW@1161|Nostocales	1117|Cyanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
HKD3_k127_7041_1	315749.Bcer98_2319	1.841e-161	517.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZB09@1386|Bacillus	91061|Bacilli	E	hydrolase activity	hipO2	-	-	ko:K01436,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD3_k127_7041_7	1345697.M493_16835	1.425e-65	226.0	2AKA0@1|root,31B0I@2|Bacteria,1V8C3@1239|Firmicutes,4HJ0A@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
HKD3_k127_7041_5	1340434.AXVA01000015_gene644	5.478e-86	289.0	COG4122@1|root,COG4122@2|Bacteria,1TYQB@1239|Firmicutes,4I7V4@91061|Bacilli,1ZE8N@1386|Bacillus	91061|Bacilli	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD3_k127_7041_6	98439.AJLL01000089_gene3806	1.462e-68	240.0	COG1285@1|root,COG1285@2|Bacteria,1G354@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	iJN678.mgtC	MgtC
HKD3_k127_7087201_1	1403313.AXBR01000014_gene2279	2.859e-130	418.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,1ZBN0@1386|Bacillus	91061|Bacilli	K	transcriptional regulatory protein	yeeN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HKD3_k127_7087201_2	1341151.ASZU01000010_gene1941	5.462e-58	203.0	COG2346@1|root,COG2346@2|Bacteria,1V930@1239|Firmicutes,4HJED@91061|Bacilli,27CC1@186824|Thermoactinomycetaceae	91061|Bacilli	C	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD3_k127_7087201_0	1403313.AXBR01000023_gene2694	3.03e-172	546.0	COG1902@1|root,COG1902@2|Bacteria,1UF7D@1239|Firmicutes,4HDMI@91061|Bacilli,1ZEPS@1386|Bacillus	91061|Bacilli	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
HKD3_k127_716973_6	315749.Bcer98_3597	4.075e-89	295.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
HKD3_k127_716973_1	315749.Bcer98_3596	5.542e-210	657.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
HKD3_k127_716973_0	1405.DJ92_2100	0.0	1030.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,1ZBUU@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	fadE	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD3_k127_716973_8	1347369.CCAD010000077_gene2911	3.427e-56	198.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,1ZH0I@1386|Bacillus	91061|Bacilli	P	Belongs to the ArsC family	yusI	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
HKD3_k127_716973_7	1347369.CCAD010000077_gene2910	2.956e-62	216.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,1ZGG0@1386|Bacillus	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
HKD3_k127_716973_10	315749.Bcer98_3585	2.132e-52	186.0	COG1658@1|root,COG1658@2|Bacteria,1VBXW@1239|Firmicutes,4HN3Z@91061|Bacilli,1ZQRT@1386|Bacillus	91061|Bacilli	L	TOPRIM	rnmV_1	-	-	ko:K07476	-	-	-	-	ko00000	-	-	-	Toprim
HKD3_k127_716973_11	315749.Bcer98_3584	1.574e-35	140.0	COG0526@1|root,COG0526@2|Bacteria,1VEVR@1239|Firmicutes,4HNM9@91061|Bacilli,1ZIVX@1386|Bacillus	91061|Bacilli	CO	Thioredoxin	yusE	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD3_k127_716973_12	1169144.KB910995_gene3069	3.193e-18	88.0	29S71@1|root,30DBI@2|Bacteria,1UB41@1239|Firmicutes,4IMGM@91061|Bacilli,1ZK48@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_716973_2	574375.BAGA_11440	2.683e-158	505.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	iYO844.BSU32750	ABC_tran,NIL
HKD3_k127_716973_5	665952.HMPREF1015_01099	7.65e-103	338.0	COG2011@1|root,COG2011@2|Bacteria,1TR59@1239|Firmicutes,4H9NA@91061|Bacilli,1ZCW0@1386|Bacillus	91061|Bacilli	P	COG2011 ABC-type metal ion transport system, permease component	metI	GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348	-	ko:K02069,ko:K02072	ko02010,map02010	M00211,M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24,9.B.25.1	-	-	BPD_transp_1
HKD3_k127_716973_4	315749.Bcer98_3580	5.396e-128	413.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,1ZATZ@1386|Bacillus	91061|Bacilli	P	Belongs to the NlpA lipoprotein family	metQ	-	-	ko:K02072,ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD3_k127_716973_3	198094.BA_5217	1.156e-147	469.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,1ZAW4@1386|Bacillus	91061|Bacilli	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HKD3_k127_716973_9	574375.BAGA_11415	3.536e-54	193.0	COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,1ZATY@1386|Bacillus	91061|Bacilli	O	assembly protein SufD	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HKD3_k127_71962_60	315730.BcerKBAB4_4415	2.321e-06	50.0	COG1971@1|root,COG1971@2|Bacteria,1V4BC@1239|Firmicutes,4HH29@91061|Bacilli,1ZCPR@1386|Bacillus	91061|Bacilli	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD3_k127_71962_32	574376.BAMA_02430	9.323e-123	398.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,1ZCC9@1386|Bacillus	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HKD3_k127_71962_0	260799.BAS4482	0.0	1401.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
HKD3_k127_71962_7	574376.BAMA_02420	7.829e-246	771.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus	91061|Bacilli	T	Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
HKD3_k127_71962_39	1408303.JNJJ01000002_gene3956	1.612e-111	364.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,1ZBGS@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_71962_25	1169144.KB910962_gene3008	1.296e-175	553.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZC27@1386|Bacillus	91061|Bacilli	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HKD3_k127_71962_5	1169144.KB910962_gene3007	2.907e-257	797.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus	91061|Bacilli	C	isocitrate	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD3_k127_71962_20	1169144.KB910962_gene3006	1.695e-193	608.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1ZBAY@1386|Bacillus	91061|Bacilli	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD3_k127_71962_47	315730.BcerKBAB4_4425	1.727e-65	228.0	COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4HIWS@91061|Bacilli,1ZRXU@1386|Bacillus	91061|Bacilli	S	UPF0756 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF441
HKD3_k127_71962_29	1405.DJ92_1682	1.274e-153	493.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,4HC6G@91061|Bacilli,1ZBXK@1386|Bacillus	91061|Bacilli	S	sporulation integral membrane protein YtvI	ytvI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_71962_56	574376.BAMA_02380	4.643e-38	146.0	COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,4HMBE@91061|Bacilli,1ZQRN@1386|Bacillus	91061|Bacilli	S	FxsA cytoplasmic membrane protein	fxsA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
HKD3_k127_71962_3	315730.BcerKBAB4_4428	1.879e-312	964.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HKD3_k127_71962_23	574376.BAMA_02370	6.914e-189	591.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,1ZB3D@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	iYO844.BSU29190	PFK
HKD3_k127_71962_27	1169144.KB910962_gene3000	2.159e-164	522.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,1ZC5V@1386|Bacillus	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
HKD3_k127_71962_31	1295642.H839_14289	9.318e-140	448.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,1WFFA@129337|Geobacillus	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD3_k127_71962_48	1405.DJ92_1688	3.087e-62	220.0	COG2186@1|root,COG2186@2|Bacteria,1V3Z4@1239|Firmicutes,4HI3J@91061|Bacilli,1ZDS7@1386|Bacillus	91061|Bacilli	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
HKD3_k127_71962_13	1169144.KB910962_gene2997	1.019e-226	707.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZBAH@1386|Bacillus	91061|Bacilli	C	Malate dehydrogenase	ytsJ	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
HKD3_k127_71962_1	1033734.CAET01000071_gene2569	0.0	1223.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HKD3_k127_71962_50	1405.DJ92_1691	3.018e-51	184.0	2CBNY@1|root,330BE@2|Bacteria,1VGPH@1239|Firmicutes,4HNX7@91061|Bacilli,1ZH6P@1386|Bacillus	91061|Bacilli	S	Sporulation protein YtrH	ytrH	-	-	-	-	-	-	-	-	-	-	-	Spore_YtrH
HKD3_k127_71962_53	1405.DJ92_1692	1.04e-45	170.0	2AV7G@1|root,31KY3@2|Bacteria,1V73K@1239|Firmicutes,4HJ3F@91061|Bacilli,1ZHIX@1386|Bacillus	91061|Bacilli	-	-	ytrI	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_71962_28	1169144.KB910962_gene2993	6.627e-159	505.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,1ZB08@1386|Bacillus	91061|Bacilli	S	COG0618 Exopolyphosphatase-related proteins	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD3_k127_71962_10	1396.DJ87_267	6.581e-233	725.0	COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,1ZB1Q@1386|Bacillus	91061|Bacilli	K	transcriptional regulator containing CBS domains	ytoI	-	-	-	-	-	-	-	-	-	-	-	4HBT,CBS,DRTGG,GntR,HTH_24
HKD3_k127_71962_37	198094.BA_4860	8.174e-113	367.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,1ZBI0@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0173 family	ytkL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
HKD3_k127_71962_24	574376.BAMA_02295	1.01e-176	561.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HKD3_k127_71962_17	1169144.KB910929_gene1807	5.002e-203	637.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,1ZBQE@1386|Bacillus	91061|Bacilli	E	Belongs to the AlaDH PNT family	ald	GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD3_k127_71962_33	1396.DJ87_253	1.053e-121	394.0	COG1028@1|root,COG1028@2|Bacteria,1TSQV@1239|Firmicutes,4HB3U@91061|Bacilli,1ZC75@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ytkK	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD3_k127_71962_45	1396.DJ87_252	2.017e-74	252.0	COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,1ZGY4@1386|Bacillus	91061|Bacilli	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD3_k127_71962_9	315749.Bcer98_3305	1.189e-237	741.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,1ZD3C@1386|Bacillus	91061|Bacilli	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HKD3_k127_71962_11	198094.BA_4880	8.028e-233	723.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,1ZC1P@1386|Bacillus	91061|Bacilli	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
HKD3_k127_71962_55	315749.Bcer98_3307	5.759e-40	150.0	2DDRJ@1|root,32U1X@2|Bacteria,1VCE7@1239|Firmicutes,4HKC5@91061|Bacilli,1ZI76@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_71962_38	1169144.KB910929_gene1797	2.948e-112	369.0	28I6D@1|root,2ZAC7@2|Bacteria,1UYC6@1239|Firmicutes,4HFH1@91061|Bacilli,1ZC06@1386|Bacillus	91061|Bacilli	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
HKD3_k127_71962_22	1405.DJ92_1729	2.474e-190	601.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,1ZDDX@1386|Bacillus	91061|Bacilli	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HKD3_k127_71962_30	315730.BcerKBAB4_4469	4.277e-150	481.0	COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,1ZBZ7@1386|Bacillus	91061|Bacilli	L	DNA methylase	ytxK	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
HKD3_k127_71962_42	1169144.KB910929_gene1793	8.275e-89	295.0	COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,1ZARA@1386|Bacillus	91061|Bacilli	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
HKD3_k127_71962_51	1405.DJ92_1733	3.633e-48	176.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli,1ZG9C@1386|Bacillus	91061|Bacilli	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HKD3_k127_71962_58	574376.BAMA_02185	4.711e-33	136.0	2E5MF@1|root,330CC@2|Bacteria,1VEG0@1239|Firmicutes,4HMVE@91061|Bacilli,1ZBQY@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2953)	ytfI	-	-	-	-	-	-	-	-	-	-	-	DUF2953
HKD3_k127_71962_18	260799.BAS4541	1.863e-200	638.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZBDY@1386|Bacillus	91061|Bacilli	S	amidohydrolase	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD3_k127_71962_4	574376.BAMA_02160	2.738e-282	873.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZCDC@1386|Bacillus	91061|Bacilli	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	ytcI	GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_71962_59	1460640.JCM19046_329	4.082e-23	99.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus	91061|Bacilli	S	spore protein	-	-	-	ko:K06418,ko:K06419	-	-	-	-	ko00000	-	-	-	SASP
HKD3_k127_71962_19	315749.Bcer98_3321	1.48e-198	633.0	COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,1ZAWX@1386|Bacillus	91061|Bacilli	D	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization	ezrA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	-	ko:K06286	-	-	-	-	ko00000,ko03036	-	-	-	EzrA
HKD3_k127_71962_44	1396.DJ87_217	2.875e-75	259.0	COG1309@1|root,COG1309@2|Bacteria,1V6TA@1239|Firmicutes,4HISQ@91061|Bacilli,1ZGRH@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yttP	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_71962_46	1382358.JHVN01000012_gene2118	6.564e-71	243.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,21VMM@150247|Anoxybacillus	91061|Bacilli	T	GAF domain	ytsP	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
HKD3_k127_71962_35	491915.Aflv_0465	6.03e-116	376.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,21VGW@150247|Anoxybacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD3_k127_71962_12	545693.BMQ_4811	7.22e-228	711.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD3_k127_71962_2	1405.DJ92_1757	0.0	1022.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZBDX@1386|Bacillus	91061|Bacilli	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_71962_36	574375.BAGA_25310	2.996e-115	373.0	COG0454@1|root,COG0454@2|Bacteria,1TSEY@1239|Firmicutes,4HA1V@91061|Bacilli,1ZANI@1386|Bacillus	91061|Bacilli	K	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue	acuA	GO:0001101,GO:0003674,GO:0003824,GO:0006066,GO:0006355,GO:0006950,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009267,GO:0009605,GO:0009847,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010034,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016407,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019152,GO:0019219,GO:0019222,GO:0019751,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032502,GO:0033554,GO:0034077,GO:0034078,GO:0034311,GO:0034313,GO:0042149,GO:0042180,GO:0042182,GO:0042221,GO:0042594,GO:0042844,GO:0042846,GO:0043894,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045013,GO:0045014,GO:0045149,GO:0045150,GO:0045892,GO:0045934,GO:0045990,GO:0046015,GO:0046164,GO:0046174,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0061984,GO:0061985,GO:0061986,GO:0065007,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071311,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1901700,GO:1901701,GO:1902652,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K04766	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD3_k127_71962_41	1169144.KB910929_gene1765	9.097e-95	314.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,1ZBNZ@1386|Bacillus	91061|Bacilli	S	Acetoin utilization protein AcuB	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
HKD3_k127_71962_15	1169144.KB910929_gene1764	8.093e-212	662.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus	91061|Bacilli	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	iYO844.BSU29710	Hist_deacetyl
HKD3_k127_71962_26	315749.Bcer98_3342	6.93e-174	551.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,1ZCFZ@1386|Bacillus	91061|Bacilli	K	catabolite control protein A	ccpA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HKD3_k127_71962_21	574375.BAGA_25380	2.275e-191	601.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,1ZB0X@1386|Bacillus	91061|Bacilli	E	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate	aroA	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD3_k127_71962_57	1169144.KB910929_gene1757	2.051e-35	137.0	COG3118@1|root,COG3118@2|Bacteria,1VEPC@1239|Firmicutes,4HNXE@91061|Bacilli,1ZI6R@1386|Bacillus	91061|Bacilli	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
HKD3_k127_71962_52	315749.Bcer98_3345	8.015e-46	170.0	COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,1ZGYS@1386|Bacillus	91061|Bacilli	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	ytxG	-	-	-	-	-	-	-	-	-	-	-	DUF948
HKD3_k127_71962_14	1396.DJ87_189	1.325e-217	678.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4HBUQ@91061|Bacilli,1ZD71@1386|Bacillus	91061|Bacilli	E	aminopeptidase	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
HKD3_k127_71962_8	1169144.KB911003_gene2778	2.14e-243	756.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,1ZB5U@1386|Bacillus	91061|Bacilli	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD3_k127_71962_16	1169144.KB911003_gene2777	2.989e-208	650.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus	91061|Bacilli	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD3_k127_71962_6	315749.Bcer98_3351	5.099e-257	816.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	sftA	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Ftsk_gamma
HKD3_k127_71962_40	260799.BAS4587	8.69e-96	316.0	COG0073@1|root,COG0073@2|Bacteria,1V3R1@1239|Firmicutes,4HHBI@91061|Bacilli,1ZD7F@1386|Bacillus	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	ytpR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	-	ko:K06878	-	-	-	-	ko00000	-	-	-	DUF4479,tRNA_bind
HKD3_k127_71962_34	1396.DJ87_179	3.207e-119	388.0	COG4848@1|root,COG4848@2|Bacteria,1TTBU@1239|Firmicutes,4HAD1@91061|Bacilli,1ZBQ7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0354 family	ytpQ	-	-	-	-	-	-	-	-	-	-	-	DUF1444
HKD3_k127_71962_54	1461580.CCAS010000010_gene1390	1.617e-44	163.0	COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,1ZHAS@1386|Bacillus	91061|Bacilli	CO	Thioredoxin	ytpP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD3_k127_71962_49	260799.BAS4590	2.402e-60	213.0	COG1986@1|root,COG1986@2|Bacteria,1V6CG@1239|Firmicutes,4HIVY@91061|Bacilli,1ZGKX@1386|Bacillus	91061|Bacilli	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	yjjX	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
HKD3_k127_71962_43	574375.BAGA_25470	7.001e-86	285.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZAXE@1386|Bacillus	91061|Bacilli	G	COG1363 Cellulase M and related proteins	pepA	-	3.4.11.7	ko:K01261,ko:K01269	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M42
HKD3_k127_7251650_0	315749.Bcer98_0076	1.023e-303	934.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD3_k127_7251650_1	1169144.KB910959_gene3951	1.276e-171	544.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,1ZBJU@1386|Bacillus	91061|Bacilli	E	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity	mcsB	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
HKD3_k127_7256422_17	406124.ACPC01000013_gene906	4.551e-78	264.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,4HBJD@91061|Bacilli,1ZDBQ@1386|Bacillus	91061|Bacilli	E	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD3_k127_7256422_19	1169144.KB910924_gene291	2.122e-42	156.0	COG2359@1|root,COG2359@2|Bacteria,1V6G8@1239|Firmicutes,4HIQV@91061|Bacilli,1ZH05@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein S	spoVS	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
HKD3_k127_7256422_9	1169144.KB910924_gene292	2.62e-150	479.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,1ZC3D@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
HKD3_k127_7256422_1	315749.Bcer98_2430	6.359e-281	871.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,1ZBGP@1386|Bacillus	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HKD3_k127_7256422_11	545693.BMQ_4119	3.863e-149	475.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,1ZCUX@1386|Bacillus	91061|Bacilli	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HKD3_k127_7256422_21	1211814.CAPG01000037_gene2027	5.583e-31	122.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,1ZCUX@1386|Bacillus	91061|Bacilli	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HKD3_k127_7256422_4	315749.Bcer98_2432	3.626e-188	595.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,1ZC5R@1386|Bacillus	91061|Bacilli	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HKD3_k127_7256422_15	1405.DJ92_824	3.398e-89	297.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,1ZBJ2@1386|Bacillus	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06365	CDP-OH_P_transf
HKD3_k127_7256422_16	1169144.KB910924_gene298	1.308e-80	277.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1ZDC1@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
HKD3_k127_7256422_10	1169144.KB910924_gene299	1.023e-149	475.0	28HGR@1|root,2Z7SI@2|Bacteria,1TRXV@1239|Firmicutes,4HA2I@91061|Bacilli,1ZAU1@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3388)	ymfK	-	-	-	-	-	-	-	-	-	-	-	DUF3388
HKD3_k127_7256422_20	315749.Bcer98_2436	3.169e-35	136.0	2E5KP@1|root,330BT@2|Bacteria,1VGM7@1239|Firmicutes,4HNNX@91061|Bacilli,1ZHTB@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3243)	ymfJ	-	-	-	-	-	-	-	-	-	-	-	DUF3243
HKD3_k127_7256422_14	198094.BA_3921	5.915e-94	314.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,4HEU2@91061|Bacilli,1ZCIS@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ymfI	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HKD3_k127_7256422_3	1169144.KB910924_gene302	1.923e-207	652.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,1ZBXQ@1386|Bacillus	91061|Bacilli	S	zinc protease	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD3_k127_7256422_5	1396.DJ87_1144	8.676e-175	557.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,1ZCAJ@1386|Bacillus	91061|Bacilli	S	Peptidase M16	albE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
HKD3_k127_7256422_6	315730.BcerKBAB4_3559	1.334e-173	547.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,1ZAYF@1386|Bacillus	91061|Bacilli	S	Belongs to the binding-protein-dependent transport system permease family	yufQ	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HKD3_k127_7256422_8	1034347.CAHJ01000010_gene2009	2.799e-158	505.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,1ZCTP@1386|Bacillus	91061|Bacilli	S	Belongs to the binding-protein-dependent transport system permease family	yufP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HKD3_k127_7256422_2	1396.DJ87_1141	6.335e-276	854.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus	91061|Bacilli	S	ABC transporter, ATP-binding protein	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HKD3_k127_7256422_7	260799.BAS3643	1.196e-169	539.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus	91061|Bacilli	S	ABC-type transport system, periplasmic component surface lipoprotein	tcsA	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
HKD3_k127_7256422_12	1169144.KB910924_gene308	2.808e-126	407.0	COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,4H9TG@91061|Bacilli,1ZB5M@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ymfC	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
HKD3_k127_7256422_0	574376.BAMA_08335	0.0	1135.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HKD3_k127_7256422_22	1169144.KB910924_gene311	5.241e-16	79.0	2DR6C@1|root,33ACS@2|Bacteria,1VM75@1239|Firmicutes,4HR6M@91061|Bacilli,1ZJYN@1386|Bacillus	91061|Bacilli	S	YlzJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YlzJ
HKD3_k127_7256422_13	1405.DJ92_838	1.873e-125	406.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,4H9XG@91061|Bacilli,1ZBH5@1386|Bacillus	91061|Bacilli	OU	COG0740 Protease subunit of ATP-dependent Clp proteases	tepA	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
HKD3_k127_7256422_18	1169144.KB910924_gene313	1.2e-65	227.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD3_k127_7285979_2	398767.Glov_0133	4.157e-33	134.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD3_k127_7285979_1	1449343.JQLQ01000002_gene910	1.26e-74	255.0	COG2128@1|root,COG2128@2|Bacteria,1VAK9@1239|Firmicutes,4HQMH@91061|Bacilli	91061|Bacilli	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD3_k127_7285979_0	1234664.AMRO01000021_gene1057	3.637e-136	452.0	COG0469@1|root,COG0469@2|Bacteria,1UYUI@1239|Firmicutes,4HE41@91061|Bacilli,1WF0X@129337|Geobacillus	91061|Bacilli	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
HKD3_k127_7289568_0	1405.DJ92_3105	2.293e-216	678.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus	91061|Bacilli	E	glutamate synthase	gltA2	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HKD3_k127_7289568_1	1169144.KB910940_gene2565	9.655e-216	676.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus	91061|Bacilli	V	ABC transporter	ygaD	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
HKD3_k127_7291305_1	99598.Cal7507_5897	1.567e-47	183.0	COG1216@1|root,COG1216@2|Bacteria,1G346@1117|Cyanobacteria,1HIR4@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_7291305_0	1408254.T458_04940	5.109e-145	471.0	COG1215@1|root,COG1215@2|Bacteria,1VUUB@1239|Firmicutes,4HVMJ@91061|Bacilli,26RQC@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_7299530_1	1211814.CAPG01000027_gene1098	4.427e-175	556.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1ZBK3@1386|Bacillus	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HKD3_k127_7299530_0	491915.Aflv_0303	1.504e-316	983.0	COG0425@1|root,COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,21WMD@150247|Anoxybacillus	91061|Bacilli	OP	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HKD3_k127_7311192_0	260799.BAS2199	2.252e-52	185.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,1ZAP5@1386|Bacillus	91061|Bacilli	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
HKD3_k127_7311192_2	1196029.ALIM01000034_gene1781	1.918e-13	73.0	2CGYI@1|root,32YUY@2|Bacteria,1VGI2@1239|Firmicutes,4HPBN@91061|Bacilli,1ZK65@1386|Bacillus	91061|Bacilli	S	Cold-inducible protein YdjO	ydjO	-	-	-	-	-	-	-	-	-	-	-	YdjO
HKD3_k127_7311192_1	315749.Bcer98_1763	4.933e-33	129.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZHUS@1386|Bacillus	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_7331423_7	1396.DJ87_4519	2.549e-121	401.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus	91061|Bacilli	P	COG2217 Cation transport ATPase	cadA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD3_k127_7331423_16	574376.BAMA_06955	6.689e-43	159.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,1ZGXI@1386|Bacillus	91061|Bacilli	K	transcriptional	czrA	-	-	ko:K21903,ko:K22043	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HKD3_k127_7331423_19	1395513.P343_00605	3.132e-28	121.0	COG3976@1|root,COG3976@2|Bacteria,1VBTI@1239|Firmicutes	1239|Firmicutes	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
HKD3_k127_7331423_9	913865.DOT_5764	3.575e-101	337.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,263US@186807|Peptococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD3_k127_7331423_10	545693.BMQ_0217	1.274e-85	293.0	COG4658@1|root,COG4658@2|Bacteria,1V4CY@1239|Firmicutes,4HHSS@91061|Bacilli,1ZEKG@1386|Bacillus	91061|Bacilli	C	NQR2, RnfD, RnfE family	-	-	-	-	-	-	-	-	-	-	-	-	NQR2_RnfD_RnfE
HKD3_k127_7331423_8	545693.BMQ_0216	4.124e-118	393.0	COG5002@1|root,COG5002@2|Bacteria,1TS5K@1239|Firmicutes,4H9Y1@91061|Bacilli,1ZS52@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	ciaH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K14982	ko02020,ko02024,map02020,map02024	M00521	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_7331423_12	913865.DOT_5767	7.039e-79	269.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,261DT@186807|Peptococcaceae	186801|Clostridia	K	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_7331423_17	1295642.H839_03606	4.978e-41	157.0	COG0789@1|root,COG0789@2|Bacteria,1VABB@1239|Firmicutes,4HMSS@91061|Bacilli,1WGNW@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD3_k127_7331423_4	1121091.AUMP01000003_gene2530	8.178e-168	534.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,4HBDK@91061|Bacilli	91061|Bacilli	G	COG1363 Cellulase M and related proteins	yhfE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD3_k127_7331423_1	574376.BAMA_03330	0.0	1244.0	COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus	91061|Bacilli	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD3_k127_7331423_2	574376.BAMA_03335	0.0	1150.0	COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,1ZBMM@1386|Bacillus	91061|Bacilli	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_7331423_14	574376.BAMA_03340	6.502e-68	232.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,1ZG6W@1386|Bacillus	91061|Bacilli	S	CoA-binding protein	yneT	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
HKD3_k127_7331423_5	1169144.KB910952_gene3196	8.67e-155	497.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_7331423_6	574376.BAMA_03355	1.192e-123	398.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HEJ8@91061|Bacilli,1ZFPI@1386|Bacillus	91061|Bacilli	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_7331423_11	260799.BAS3399	1.513e-82	278.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,1ZFP9@1386|Bacillus	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HKD3_k127_7331423_18	574376.BAMA_03375	6.214e-36	138.0	COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,1ZHU4@1386|Bacillus	91061|Bacilli	S	Belongs to the HesB IscA family	yneR	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
HKD3_k127_7331423_13	315730.BcerKBAB4_3293	6.51e-69	237.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,1ZQR3@1386|Bacillus	91061|Bacilli	S	Thioesterase-like superfamily	yneP	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD3_k127_7331423_3	1405.DJ92_581	3.716e-206	649.0	COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus	91061|Bacilli	M	Glycoside Hydrolase Family	yaaH	-	-	ko:K06306	-	-	-	-	ko00000	-	-	-	Glyco_hydro_18,LysM
HKD3_k127_7331423_25	1405.DJ92_582	1.18e-13	73.0	2E62M@1|root,330RR@2|Bacteria,1VF8M@1239|Firmicutes,4HPWY@91061|Bacilli,1ZITR@1386|Bacillus	91061|Bacilli	S	Belongs to the Tlp family	tlp	-	-	ko:K06434	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_7331423_15	1405.DJ92_586	1.931e-52	191.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD3_k127_7331423_0	1134413.ANNK01000085_gene413	0.0	1458.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus	91061|Bacilli	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	citB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06730	Aconitase,Aconitase_C
HKD3_k127_7331423_21	315749.Bcer98_2265	8.491e-20	89.0	2EI8E@1|root,33BZS@2|Bacteria,1VNNB@1239|Firmicutes,4HS1A@91061|Bacilli,1ZIU1@1386|Bacillus	91061|Bacilli	S	Belongs to the SspO family	sspO	-	-	ko:K06432	-	-	-	-	ko00000	-	-	-	SspO
HKD3_k127_7331423_20	574376.BAMA_03425	5.637e-24	104.0	2CNCH@1|root,32SGT@2|Bacteria,1VDMW@1239|Firmicutes,4HMYB@91061|Bacilli,1ZIW4@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7331423_23	1169144.KB911006_gene2424	1.119e-16	84.0	COG0071@1|root,COG0071@2|Bacteria,1W6SQ@1239|Firmicutes,4I0M1@91061|Bacilli,1ZHFP@1386|Bacillus	91061|Bacilli	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K06335,ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD3_k127_7331423_22	1396.DJ87_1330	1.147e-19	90.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
HKD3_k127_7334012_6	574376.BAMA_23425	4.318e-68	235.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD3_k127_7334012_0	1405.DJ92_3048	4.434e-318	983.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus	91061|Bacilli	P	COG2217 Cation transport ATPase	zosA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
HKD3_k127_7334012_5	1405.DJ92_3055	3.243e-74	254.0	COG0586@1|root,COG0586@2|Bacteria,1V8A4@1239|Firmicutes,4HHUU@91061|Bacilli,1ZH0M@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	ybfM	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD3_k127_7334012_2	1169144.KB910955_gene245	2.797e-145	468.0	COG4632@1|root,COG4632@2|Bacteria,1TP2R@1239|Firmicutes,4HK3I@91061|Bacilli	91061|Bacilli	G	Exopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
HKD3_k127_7334012_11	1405.DJ92_3057	1.519e-15	77.0	2EMUQ@1|root,33FH0@2|Bacteria,1VMZF@1239|Firmicutes,4I148@91061|Bacilli,1ZKE2@1386|Bacillus	91061|Bacilli	S	-transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7334012_10	198094.BA_0417	1.29e-17	83.0	2EMUQ@1|root,33FH0@2|Bacteria,1VMZF@1239|Firmicutes,4I148@91061|Bacilli,1ZKE2@1386|Bacillus	91061|Bacilli	S	-transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7334012_8	574376.BAMA_23450	1.184e-50	183.0	COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus	91061|Bacilli	S	general stress protein	ydaG	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyrid_ox_like
HKD3_k127_7334012_1	315730.BcerKBAB4_0399	3.438e-171	542.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,4HB3X@91061|Bacilli,1ZC9V@1386|Bacillus	91061|Bacilli	P	COG0387 Ca2 H antiporter	cax	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
HKD3_k127_7334012_7	265729.GS18_0219345	1.169e-56	204.0	COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus	91061|Bacilli	S	Membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	YitT_membrane
HKD3_k127_7334012_3	935837.JAEK01000038_gene2864	4.676e-104	344.0	28IN6@1|root,2Z8NK@2|Bacteria,1TR7N@1239|Firmicutes,4HBDQ@91061|Bacilli,1ZBTH@1386|Bacillus	91061|Bacilli	S	YfkD-like protein	yfkD	-	-	-	-	-	-	-	-	-	-	-	YfkD
HKD3_k127_7334012_9	545693.BMQ_3507	3.808e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,1VC1N@1239|Firmicutes,4HJT0@91061|Bacilli,1ZGZD@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
HKD3_k127_7334012_4	574376.BAMA_23465	1.401e-98	323.0	COG0535@1|root,COG0535@2|Bacteria,1TRC8@1239|Firmicutes,4HA9Q@91061|Bacilli,1ZAVK@1386|Bacillus	91061|Bacilli	S	YfkB-like domain	yfkA	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,YfkB
HKD3_k127_7340833_0	1169144.KB910924_gene559	9.502e-201	636.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,1ZCWW@1386|Bacillus	91061|Bacilli	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD3_k127_7340833_1	574376.BAMA_09355	1.948e-63	220.0	2ABH1@1|root,310Y3@2|Bacteria,1V4IK@1239|Firmicutes,4HI56@91061|Bacilli,1ZGD1@1386|Bacillus	91061|Bacilli	S	YkyB-like protein	ykyB	-	-	-	-	-	-	-	-	-	-	-	YkyB
HKD3_k127_7340833_2	1396.DJ87_864	1.34e-53	195.0	COG0497@1|root,COG0497@2|Bacteria,1V4G3@1239|Firmicutes,4HHDM@91061|Bacilli,1ZH4B@1386|Bacillus	91061|Bacilli	L	Putative cell-wall binding lipoprotein	ykyA	-	-	-	-	-	-	-	-	-	-	-	YkyA
HKD3_k127_7340833_3	574375.BAGA_01455	2.45e-27	112.0	296CX@1|root,2ZTNP@2|Bacteria,1W1Y7@1239|Firmicutes,4I1ZM@91061|Bacilli,1ZPMF@1386|Bacillus	91061|Bacilli	S	SPP1 phage holin	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
HKD3_k127_7340833_4	1169144.KB910924_gene564	6.352e-24	106.0	29SUS@1|root,30E0X@2|Bacteria,1UBZP@1239|Firmicutes,4INFJ@91061|Bacilli,1ZNEK@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_735688_5	1121091.AUMP01000007_gene1056	1.352e-21	98.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HN1F@91061|Bacilli	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD3_k127_735688_0	545243.BAEV01000022_gene2019	0.0	1097.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,36DHG@31979|Clostridiaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
HKD3_k127_735688_3	1174504.AJTN02000193_gene4040	2.12e-135	445.0	COG0500@1|root,COG2226@2|Bacteria,1UIHW@1239|Firmicutes,4HCCW@91061|Bacilli,1ZRT4@1386|Bacillus	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HKD3_k127_735688_4	574376.BAMA_24330	2.539e-101	346.0	COG1807@1|root,COG1807@2|Bacteria,1V114@1239|Firmicutes,4HB64@91061|Bacilli,1ZDJ4@1386|Bacillus	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD3_k127_735688_2	265729.GS18_0216325	1.45e-153	496.0	COG2124@1|root,COG2124@2|Bacteria,1TSC5@1239|Firmicutes,4HBG5@91061|Bacilli,1ZQAT@1386|Bacillus	91061|Bacilli	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HKD3_k127_735688_1	935845.JADQ01000041_gene2214	2.364e-291	899.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,26RRG@186822|Paenibacillaceae	91061|Bacilli	S	Heme ABC transporter ATP-binding protein	yheS_1	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD3_k127_735688_6	1132442.KB889752_gene1824	1.066e-15	78.0	COG1215@1|root,COG1215@2|Bacteria,1TSD3@1239|Firmicutes,4HD23@91061|Bacilli,1ZFCB@1386|Bacillus	91061|Bacilli	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,Glycos_transf_2,PilZ
HKD3_k127_7437357_13	574376.BAMA_22005	6.026e-32	131.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HKD3_k127_7437357_7	315749.Bcer98_3052	7.903e-89	295.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HEJU@91061|Bacilli,1ZQ4K@1386|Bacillus	91061|Bacilli	F	ComE operon protein 2	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HKD3_k127_7437357_10	315730.BcerKBAB4_4178	5.481e-53	192.0	COG1555@1|root,COG1596@1|root,COG1555@2|Bacteria,COG1596@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,1ZH4N@1386|Bacillus	91061|Bacilli	L	COG1555 DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HKD3_k127_7437357_3	1405.DJ92_1433	1.144e-109	361.0	COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZBFA@1386|Bacillus	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	comER	-	-	ko:K02239	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	F420_oxidored,P5CR_dimer
HKD3_k127_7437357_4	1396.DJ87_535	1.367e-102	339.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,1ZB0Y@1386|Bacillus	91061|Bacilli	Q	Methyltransferase	yqeM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD3_k127_7437357_11	1211814.CAPG01000046_gene2461	3.762e-52	186.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,1ZGYR@1386|Bacillus	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HKD3_k127_7437357_9	1382315.JPOI01000001_gene1767	1.003e-67	237.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1WFI5@129337|Geobacillus	91061|Bacilli	H	Metal dependent phosphohydrolases with conserved 'HD' motif.	yqeK	-	-	-	-	-	-	-	-	-	-	-	HD
HKD3_k127_7437357_6	1169144.KB910958_gene3906	5.592e-90	299.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD3_k127_7437357_12	1169144.KB910958_gene3905	6.022e-45	164.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,1ZH83@1386|Bacillus	91061|Bacilli	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
HKD3_k127_7437357_1	574375.BAGA_03220	2.431e-118	385.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,1ZANW@1386|Bacillus	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HKD3_k127_7437357_0	1169144.KB910958_gene3903	2.458e-195	613.0	COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,1ZBES@1386|Bacillus	91061|Bacilli	S	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis	yqeH	GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113	-	ko:K06948	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HKD3_k127_7437357_8	315730.BcerKBAB4_4187	1.054e-74	254.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,1ZFKN@1386|Bacillus	91061|Bacilli	S	hydrolase of the HAD superfamily	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
HKD3_k127_7437357_2	574375.BAGA_03240	1.115e-110	362.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,1ZAZ4@1386|Bacillus	91061|Bacilli	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HKD3_k127_7437357_5	1169144.KB910958_gene3899	1.919e-96	317.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,4HBY2@91061|Bacilli,1ZB3Q@1386|Bacillus	91061|Bacilli	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD3_k127_7463793_5	1384057.CD33_11695	2.087e-57	203.0	COG0454@1|root,COG0456@2|Bacteria,1TSZY@1239|Firmicutes,4HAYD@91061|Bacilli	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yjbC	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
HKD3_k127_7463793_2	666686.B1NLA3E_04690	1.598e-176	558.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU11190	Semialdhyde_dh,Semialdhyde_dhC
HKD3_k127_7463793_1	666686.B1NLA3E_04695	7.633e-186	588.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HKD3_k127_7463793_4	666686.B1NLA3E_04700	5.262e-108	355.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,1ZF3H@1386|Bacillus	91061|Bacilli	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_7463793_3	666686.B1NLA3E_04705	4.407e-175	556.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,1ZC2Y@1386|Bacillus	91061|Bacilli	E	acetylornithine aminotransferase	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_7463793_0	1384057.CD33_11715	2.268e-246	775.0	2C593@1|root,2Z84R@2|Bacteria,1U546@1239|Firmicutes,4HEHB@91061|Bacilli	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7481394_6	1499680.CCFE01000008_gene33	1.309e-24	103.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD3_k127_7481394_2	1405.DJ92_1495	1.123e-192	606.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus	91061|Bacilli	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD3_k127_7481394_5	1405.DJ92_1496	2.132e-72	245.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,4HHCF@91061|Bacilli,1ZFKT@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	cymR	GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044212,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:1901363	-	ko:K17472	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
HKD3_k127_7481394_3	1408303.JNJJ01000037_gene28	7.23e-170	542.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,1ZBCW@1386|Bacillus	91061|Bacilli	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD3_k127_7481394_4	315749.Bcer98_3117	3.571e-141	451.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,4H9KZ@91061|Bacilli,1ZBGG@1386|Bacillus	91061|Bacilli	H	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	yrvM	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
HKD3_k127_7481394_0	574375.BAGA_03570	1.167e-305	945.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,1ZBXI@1386|Bacillus	91061|Bacilli	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HKD3_k127_7481394_1	1405.DJ92_1501	8.335e-230	715.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,1ZBXR@1386|Bacillus	91061|Bacilli	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His
HKD3_k127_7484754_4	562970.Btus_2895	2.359e-114	376.0	COG0834@1|root,COG0834@2|Bacteria,1TSB9@1239|Firmicutes,4HF2H@91061|Bacilli	91061|Bacilli	ET	extracellular solute-binding protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD3_k127_7484754_2	1243664.CAVL020000026_gene1178	2.637e-133	440.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZC5H@1386|Bacillus	91061|Bacilli	KT	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_4,PAS_9,Sigma54_activat
HKD3_k127_7484754_1	315749.Bcer98_0009	1.987e-186	592.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD3_k127_7484754_0	315749.Bcer98_0008	4.067e-283	873.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,1ZC91@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HKD3_k127_7484754_3	574376.BAMA_18560	6.825e-119	391.0	28JUG@1|root,2Z9JI@2|Bacteria,1UYYT@1239|Firmicutes,4HC3E@91061|Bacilli,1ZBYK@1386|Bacillus	91061|Bacilli	S	YaaC-like Protein	yaaC	-	-	-	-	-	-	-	-	-	-	-	YaaC
HKD3_k127_7484754_5	1051501.AYTL01000027_gene413	4.406e-10	60.0	2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli,1ZJ7K@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7517960_7	1295642.H839_09313	9.578e-08	55.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,4HJDZ@91061|Bacilli,1WFPG@129337|Geobacillus	91061|Bacilli	S	SdpI/YhfL protein family	yvaZ	GO:0008150,GO:0009636,GO:0042221,GO:0050896	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
HKD3_k127_7517960_6	315730.BcerKBAB4_3847	6.715e-22	102.0	299N6@1|root,2ZWQH@2|Bacteria,1W3UT@1239|Firmicutes,4I20Q@91061|Bacilli,1ZK2N@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3997
HKD3_k127_7517960_3	315749.Bcer98_2719	2.266e-55	197.0	COG1714@1|root,COG1714@2|Bacteria,1UBPU@1239|Firmicutes,4IN4N@91061|Bacilli,1ZMU5@1386|Bacillus	91061|Bacilli	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD3_k127_7517960_4	1405.DJ92_4535	7.509e-53	192.0	COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,1ZFNY@1386|Bacillus	91061|Bacilli	I	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	M1-740	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_7517960_5	198094.BA_4233	1.02e-38	151.0	COG4221@1|root,COG4221@2|Bacteria,1UBMT@1239|Firmicutes,4IN29@91061|Bacilli,1ZMMJ@1386|Bacillus	91061|Bacilli	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD3_k127_7517960_0	315730.BcerKBAB4_3837	1.526e-196	618.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus	91061|Bacilli	E	Aminotransferase	patA	-	-	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R04467	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_7517960_1	1169144.KB910924_gene568	7.386e-158	511.0	COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K07697	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD3_k127_7517960_2	1169144.KB910924_gene567	3.667e-75	260.0	29SJZ@1|root,30DR7@2|Bacteria,1UBKD@1239|Firmicutes,4IN09@91061|Bacilli,1ZMDE@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3967)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3967
HKD3_k127_7518452_2	913865.DOT_2932	4.458e-06	57.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,261JV@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
HKD3_k127_7518452_1	1211814.CAPG01000082_gene3810	5.821e-32	127.0	COG4378@1|root,COG4378@2|Bacteria,1VF4A@1239|Firmicutes,4HN41@91061|Bacilli,1ZH3X@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
HKD3_k127_7518452_0	1211814.CAPG01000003_gene100	2.852e-109	358.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,1ZDAX@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	ybhF_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_7532230_3	315730.BcerKBAB4_5607	3.412e-31	131.0	29X35@1|root,30IRS@2|Bacteria,1UJD6@1239|Firmicutes,4IT5X@91061|Bacilli,1ZHSF@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HKD3_k127_7532230_0	574375.BAGA_23370	1.674e-120	398.0	COG4974@1|root,COG4974@2|Bacteria,1VJNY@1239|Firmicutes,4HQBS@91061|Bacilli,1ZERC@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_7532230_2	1461582.BN1048_00989	2.337e-53	201.0	COG1835@1|root,COG1835@2|Bacteria,1VAGV@1239|Firmicutes,4HMP2@91061|Bacilli	91061|Bacilli	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD3_k127_7532230_1	1121091.AUMP01000039_gene1460	1.601e-66	233.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli	91061|Bacilli	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HKD3_k127_7533912_2	1042163.BRLA_c022920	2.099e-33	130.0	COG0697@1|root,COG0697@2|Bacteria,1TP9B@1239|Firmicutes,4H9TT@91061|Bacilli,26TNP@186822|Paenibacillaceae	91061|Bacilli	EG	Putative multidrug resistance efflux transporter	yjlA	-	-	-	-	-	-	-	-	-	-	-	EmrE
HKD3_k127_7533912_0	1122915.AUGY01000029_gene5840	3.324e-112	366.0	COG1814@1|root,COG1814@2|Bacteria,1V3A2@1239|Firmicutes,4HFSI@91061|Bacilli	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD3_k127_7533912_1	326423.RBAM_027290	7.654e-42	158.0	COG5522@1|root,COG5522@2|Bacteria,1V4XE@1239|Firmicutes,4HHC6@91061|Bacilli,1ZBDN@1386|Bacillus	91061|Bacilli	S	Integral membrane protein	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
HKD3_k127_7546248_4	315730.BcerKBAB4_4000	3.271e-27	111.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZASS@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
HKD3_k127_7546248_2	1134413.ANNK01000095_gene923	5.907e-58	205.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,4HJH0@91061|Bacilli,1ZGEW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF523)	ybbK	-	-	-	-	-	-	-	-	-	-	-	DUF523
HKD3_k127_7546248_0	315749.Bcer98_3787	5.059e-127	417.0	COG0845@1|root,COG0845@2|Bacteria,1V9BP@1239|Firmicutes,4HJQN@91061|Bacilli,1ZQX6@1386|Bacillus	91061|Bacilli	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD3_k127_7546248_1	666686.B1NLA3E_12130	1.392e-116	379.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,1ZC14@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	yknY	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_7546248_3	666686.B1NLA3E_12125	1.782e-53	192.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,1ZDCS@1386|Bacillus	91061|Bacilli	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	yknZ	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD3_k127_7551373_5	1121091.AUMP01000033_gene1592	2.874e-99	329.0	COG0715@1|root,COG0715@2|Bacteria,1TP8M@1239|Firmicutes,4HCBE@91061|Bacilli	91061|Bacilli	P	NMT1-like family	ssuA	-	-	ko:K15553	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	NMT1
HKD3_k127_7551373_4	666686.B1NLA3E_07845	7.49e-112	366.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	ssuB	GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0022857,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098656	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	iYO844.BSU08830	ABC_tran
HKD3_k127_7551373_1	574376.BAMA_15970	5.749e-220	685.0	COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,4HBIH@91061|Bacilli,1ZATH@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0229 family	yhbH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
HKD3_k127_7551373_0	574376.BAMA_15980	0.0	1179.0	COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus	91061|Bacilli	T	Ser protein kinase	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
HKD3_k127_7551373_6	1405.DJ92_3141	2.068e-89	296.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,1ZFKH@1386|Bacillus	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	cspR	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HKD3_k127_7551373_3	574376.BAMA_15995	4.961e-113	372.0	2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,4HCE4@91061|Bacilli,1ZC8T@1386|Bacillus	91061|Bacilli	S	Putative amidase domain	yhbB	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
HKD3_k127_7551373_2	1169144.KB910973_gene2203	1.446e-185	585.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,1ZC1W@1386|Bacillus	91061|Bacilli	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
HKD3_k127_7551373_7	1169144.KB910973_gene2204	1.507e-67	232.0	COG1651@1|root,COG1651@2|Bacteria,1V6IC@1239|Firmicutes,4HKAW@91061|Bacilli,1ZR7H@1386|Bacillus	91061|Bacilli	O	disulfide bond formation protein	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HKD3_k127_7562047_2	574376.BAMA_08800	2.942e-200	627.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,1ZB7G@1386|Bacillus	91061|Bacilli	F	Carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15510	CPSase_sm_chain,GATase
HKD3_k127_7562047_0	260799.BAS3739	7.188e-213	667.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus	91061|Bacilli	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD3_k127_7562047_3	1267580.AF6_1788	4.8e-121	395.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,21VBP@150247|Anoxybacillus	91061|Bacilli	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
HKD3_k127_7562047_1	1169144.KB910924_gene455	1.445e-210	661.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,1ZBWN@1386|Bacillus	91061|Bacilli	F	Xanthine uracil	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
HKD3_k127_7562047_4	315749.Bcer98_2540	1.167e-91	306.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,1ZB3P@1386|Bacillus	91061|Bacilli	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD3_k127_7567900_6	66692.ABC1742	1.271e-14	74.0	COG2382@1|root,COG2382@2|Bacteria,1UCAC@1239|Firmicutes,4HC02@91061|Bacilli,1ZBAQ@1386|Bacillus	91061|Bacilli	P	COG2382 Enterochelin esterase and related enzymes	yjcH	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
HKD3_k127_7567900_1	1382358.JHVN01000005_gene3041	2.395e-53	193.0	COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli,21WX9@150247|Anoxybacillus	91061|Bacilli	J	2'-5' RNA ligase superfamily	yjcG	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD3_k127_7567900_0	545693.BMQ_0742	7.567e-285	893.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZCF6@1386|Bacillus	91061|Bacilli	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CoiA,UvrD-helicase,UvrD_C
HKD3_k127_7567900_3	574376.BAMA_17565	7.729e-44	163.0	2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli,1ZHZZ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1360)	yjcA	-	-	-	-	-	-	-	-	-	-	-	DUF1360
HKD3_k127_7567900_5	345219.Bcoa_0325	6.171e-28	117.0	29X3J@1|root,30ISA@2|Bacteria,1W4UQ@1239|Firmicutes,4IMB2@91061|Bacilli,1ZJPH@1386|Bacillus	91061|Bacilli	S	Spore coat protein	-	-	-	ko:K06343,ko:K06344	-	-	-	-	ko00000	-	-	-	Spore-coat_CotZ
HKD3_k127_7567900_7	1405.DJ92_3849	5.671e-14	79.0	2EECC@1|root,3386N@2|Bacteria,1VFWU@1239|Firmicutes,4HQI6@91061|Bacilli,1ZK7H@1386|Bacillus	91061|Bacilli	S	Spore coat protein CotO	yjbX	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Spore_coat_CotO
HKD3_k127_7567900_2	1347086.CCBA010000039_gene4893	1.019e-49	187.0	COG1215@1|root,COG1215@2|Bacteria,1V7YV@1239|Firmicutes,4HKNG@91061|Bacilli,1ZH4Z@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD3_k127_7567900_4	1408254.T458_20115	4.382e-32	129.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HAY0@91061|Bacilli,26T47@186822|Paenibacillaceae	91061|Bacilli	M	Male sterility protein	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD3_k127_7594297_1	1499680.CCFE01000023_gene2510	2.938e-97	324.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus	91061|Bacilli	N	flagellar motor	motA	GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
HKD3_k127_7594297_3	1131730.BAVI_16137	1.012e-75	260.0	COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,1ZB4F@1386|Bacillus	91061|Bacilli	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
HKD3_k127_7594297_2	1234664.AMRO01000005_gene2121	5.921e-76	262.0	COG1583@1|root,COG1583@2|Bacteria,1TRPW@1239|Firmicutes,4HCMC@91061|Bacilli,1WFTZ@129337|Geobacillus	91061|Bacilli	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
HKD3_k127_7594297_0	574376.BAMA_02665	0.0	1206.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1ZBJV@1386|Bacillus	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD3_k127_7594297_4	315749.Bcer98_3241	1.056e-07	53.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus	91061|Bacilli	L	COG1796 DNA polymerase IV (family X)	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
HKD3_k127_7603989_6	315730.BcerKBAB4_4172	8.73e-185	582.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus	91061|Bacilli	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
HKD3_k127_7603989_0	315749.Bcer98_3046	0.0	1088.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
HKD3_k127_7603989_7	315749.Bcer98_3043	5.461e-171	545.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,1ZC7V@1386|Bacillus	91061|Bacilli	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD3_k127_7603989_10	574376.BAMA_22045	5.612e-160	509.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,1ZBQV@1386|Bacillus	91061|Bacilli	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
HKD3_k127_7603989_16	574376.BAMA_22050	1.757e-65	229.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,1ZGCW@1386|Bacillus	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HKD3_k127_7603989_1	315749.Bcer98_3040	0.0	1047.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus	91061|Bacilli	O	Heat shock 70 kDa protein	dnaK	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD3_k127_7603989_5	1169144.KB910958_gene3924	1.025e-198	623.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1ZC0R@1386|Bacillus	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD3_k127_7603989_12	574375.BAGA_03110	4.954e-135	436.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,1ZB7J@1386|Bacillus	91061|Bacilli	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HKD3_k127_7603989_13	574375.BAGA_03105	5.51e-113	368.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HKD3_k127_7603989_2	1169144.KB910958_gene3927	1.939e-247	768.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,1ZB8Q@1386|Bacillus	91061|Bacilli	J	ribosomal protein S12 methylthiotransferase	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD3_k127_7603989_14	574376.BAMA_22085	2.41e-98	325.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD3_k127_7603989_21	7029.ACYPI088221-PA	2.427e-24	103.0	COG0443@1|root,COG0484@1|root,KOG0102@2759|Eukaryota,KOG0715@2759|Eukaryota,38EJA@33154|Opisthokonta,3BABY@33208|Metazoa,3CT5K@33213|Bilateria,41TN6@6656|Arthropoda,3SHSX@50557|Insecta,3E7JR@33342|Paraneoptera	33154|Opisthokonta	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
HKD3_k127_7603989_17	491915.Aflv_0841	1.331e-58	206.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,21WJ3@150247|Anoxybacillus	91061|Bacilli	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HKD3_k127_7603989_19	1169144.KB910958_gene3931	6.925e-43	158.0	2E4EZ@1|root,32ZA5@2|Bacteria,1VF5C@1239|Firmicutes,4HNQG@91061|Bacilli,1ZHZA@1386|Bacillus	91061|Bacilli	S	sporulation protein YqfC	yqfC	-	-	-	-	-	-	-	-	-	-	-	YabP
HKD3_k127_7603989_11	1169144.KB910958_gene3932	2.687e-155	499.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus	91061|Bacilli	S	Stage IV sporulation	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
HKD3_k127_7603989_9	574375.BAGA_03070	4.241e-165	523.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1ZBVE@1386|Bacillus	91061|Bacilli	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HKD3_k127_7603989_3	796606.BMMGA3_11955	9.681e-219	701.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus	91061|Bacilli	S	membrane-associated HD superfamily hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
HKD3_k127_7603989_15	574375.BAGA_03060	3.741e-68	234.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,1ZG7I@1386|Bacillus	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
HKD3_k127_7603989_20	1405.DJ92_1406	3.097e-35	137.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,1ZHW0@1386|Bacillus	91061|Bacilli	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
HKD3_k127_7603989_18	1231057.AMGD01000021_gene3192	5.645e-58	205.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,26F5G@186818|Planococcaceae	91061|Bacilli	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD3_k127_7603989_8	1169144.KB910958_gene3938	1.487e-169	536.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,1ZCSH@1386|Bacillus	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD3_k127_7603989_4	1405.DJ92_4474	1.666e-216	679.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus	91061|Bacilli	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	yvdB	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HKD3_k127_7615049_1	1117379.BABA_24360	7.928e-170	540.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,1ZBID@1386|Bacillus	91061|Bacilli	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
HKD3_k127_7615049_3	1122919.KB905548_gene2217	1.546e-100	338.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,26TRR@186822|Paenibacillaceae	91061|Bacilli	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
HKD3_k127_7615049_5	1305836.AXVE01000016_gene1919	4.69e-66	233.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,4HA2E@91061|Bacilli,26EGU@186818|Planococcaceae	91061|Bacilli	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
HKD3_k127_7615049_10	1444306.JFZC01000089_gene1448	7.67e-23	101.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,4HKVS@91061|Bacilli,26P35@186821|Sporolactobacillaceae	91061|Bacilli	N	Bacterial export proteins, family 3	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
HKD3_k127_7615049_4	1089548.KI783301_gene667	2.479e-86	291.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,4HA79@91061|Bacilli,3WFF9@539002|Bacillales incertae sedis	91061|Bacilli	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
HKD3_k127_7615049_9	1461580.CCAS010000009_gene1323	4.947e-23	106.0	COG3190@1|root,COG3190@2|Bacteria,1VGFI@1239|Firmicutes,4HJJQ@91061|Bacilli,1ZQNA@1386|Bacillus	91061|Bacilli	N	Flagellar biosynthesis protein, FliO	fliZ	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
HKD3_k127_7615049_8	586413.CCDL010000002_gene2460	2.822e-24	106.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,4HC56@91061|Bacilli,23IN7@182709|Oceanobacillus	91061|Bacilli	N	Type III flagellar switch regulator (C-ring) FliN C-term	fliY	GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
HKD3_k127_7615049_12	1034769.KB910518_gene1699	5.344e-06	55.0	COG3334@1|root,COG3334@2|Bacteria,1V87H@1239|Firmicutes,4HJU9@91061|Bacilli,26RXM@186822|Paenibacillaceae	91061|Bacilli	S	MgtE intracellular N domain	ylxF	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
HKD3_k127_7615049_11	44251.PDUR_16570	4.782e-09	63.0	COG2882@1|root,COG2882@2|Bacteria,1V9X3@1239|Firmicutes,4HJQJ@91061|Bacilli,26ZBG@186822|Paenibacillaceae	91061|Bacilli	N	flagellar export protein FliJ	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
HKD3_k127_7615049_0	1117379.BABA_24400	4.215e-210	661.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4HAUY@91061|Bacilli,1ZBXU@1386|Bacillus	91061|Bacilli	NU	COG1157 Flagellar biosynthesis type III secretory pathway ATPase	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD3_k127_7615049_7	1117379.BABA_24405	6.299e-44	169.0	COG1317@1|root,COG1317@2|Bacteria,1VEUV@1239|Firmicutes,4HG3R@91061|Bacilli,1ZE47@1386|Bacillus	91061|Bacilli	NU	COG1317 Flagellar biosynthesis type III secretory pathway protein	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
HKD3_k127_7615049_2	1117379.BABA_24410	5.202e-104	347.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,4HAFZ@91061|Bacilli,1ZAQU@1386|Bacillus	91061|Bacilli	N	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
HKD3_k127_7615049_6	1117379.BABA_24415	1.971e-53	199.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus	91061|Bacilli	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
HKD3_k127_7628251_0	1395513.P343_14370	2.64e-98	334.0	COG2508@1|root,COG2508@2|Bacteria,1UJJU@1239|Firmicutes,4HD4P@91061|Bacilli,26Q1B@186821|Sporolactobacillaceae	91061|Bacilli	QT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
HKD3_k127_7628251_1	1444306.JFZC01000012_gene2045	3.532e-32	128.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,26PJV@186821|Sporolactobacillaceae	91061|Bacilli	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HKD3_k127_7632958_0	1174504.AJTN02000225_gene1871	3.034e-137	439.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus	91061|Bacilli	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
HKD3_k127_7632958_1	574376.BAMA_00400	1.651e-81	273.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus	91061|Bacilli	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD3_k127_7632958_2	634956.Geoth_2370	4.514e-23	99.0	COG0491@1|root,COG0491@2|Bacteria,1TPPD@1239|Firmicutes,4HB0S@91061|Bacilli,1WG6W@129337|Geobacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	yobT	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_7640800_5	1169144.KB910977_gene752	1.129e-20	93.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,4HBCW@91061|Bacilli,1ZCK1@1386|Bacillus	91061|Bacilli	S	membrane transporter protein	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_7640800_2	1405.DJ92_2935	2.732e-140	456.0	COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,1ZBGV@1386|Bacillus	91061|Bacilli	S	COG4851 Protein involved in sex pheromone biosynthesis	camS	-	-	-	-	-	-	-	-	-	-	-	CamS
HKD3_k127_7640800_0	574376.BAMA_22825	0.0	1037.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZATN@1386|Bacillus	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HKD3_k127_7640800_1	1423321.AS29_09450	0.0	1023.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD3_k127_7640800_3	1405.DJ92_2932	1.517e-117	381.0	COG1646@1|root,COG1646@2|Bacteria,1TQQK@1239|Firmicutes,4H9YW@91061|Bacilli,1ZBBT@1386|Bacillus	91061|Bacilli	I	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales	pcrB	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
HKD3_k127_7640800_4	315749.Bcer98_0283	5.618e-25	108.0	2EAXM@1|root,338T0@2|Bacteria,1VHD8@1239|Firmicutes,4HNTI@91061|Bacilli,1ZR95@1386|Bacillus	91061|Bacilli	S	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HKD3_k127_7641364_4	1169144.KB910926_gene1123	3.743e-145	466.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	yyxA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD3_k127_7641364_5	315749.Bcer98_4002	1.893e-140	449.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,1ZASY@1386|Bacillus	91061|Bacilli	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	vicX	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
HKD3_k127_7641364_11	1382315.JPOI01000001_gene886	1.279e-50	189.0	COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,1WG31@129337|Geobacillus	91061|Bacilli	S	YycH protein	yycI	-	-	-	-	-	-	-	-	-	-	-	YycI
HKD3_k127_7641364_7	1169144.KB910926_gene1120	8.08e-123	407.0	COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yycH	-	-	-	-	-	-	-	-	-	-	-	YycH
HKD3_k127_7641364_1	1169144.KB910926_gene1119	2.215e-302	936.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
HKD3_k127_7641364_6	1169144.KB910926_gene1118	4.572e-140	447.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1ZAT8@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_7641364_15	1499968.TCA2_5335	1.487e-11	64.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HRQH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_7641364_3	315749.Bcer98_4007	4.714e-236	734.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,1ZBF8@1386|Bacillus	91061|Bacilli	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD3_k127_7641364_2	1169144.KB910926_gene1116	1.762e-241	751.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD3_k127_7641364_10	315749.Bcer98_4009	5.999e-63	219.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,1ZGEE@1386|Bacillus	91061|Bacilli	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HKD3_k127_7641364_0	574375.BAGA_13635	0.0	1020.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus	91061|Bacilli	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
HKD3_k127_7641364_9	1169144.KB910926_gene1113	1.558e-77	269.0	COG4241@1|root,COG4241@2|Bacteria,1UZYE@1239|Firmicutes,4HAFH@91061|Bacilli,1ZC1B@1386|Bacillus	91061|Bacilli	S	membrane	yybS	-	-	-	-	-	-	-	-	-	-	-	DUF2232
HKD3_k127_7641364_13	935837.JAEK01000031_gene2652	9.64e-39	145.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,1ZHUE@1386|Bacillus	91061|Bacilli	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HKD3_k127_7641364_8	574376.BAMA_12695	9.496e-82	274.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,1ZFIJ@1386|Bacillus	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD3_k127_7641364_12	1444310.JANV01000028_gene1591	1.039e-47	173.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,1ZGZ0@1386|Bacillus	91061|Bacilli	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HKD3_k127_7694129_4	1347369.CCAD010000064_gene4013	6.15e-18	87.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,1ZIP6@1386|Bacillus	91061|Bacilli	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD3_k127_7694129_3	160799.PBOR_07440	6.862e-52	184.0	COG1742@1|root,COG1742@2|Bacteria,1V6YJ@1239|Firmicutes,4HIIY@91061|Bacilli,26YDF@186822|Paenibacillaceae	91061|Bacilli	S	UPF0060 membrane protein	yfjF	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
HKD3_k127_7694129_1	935837.JAEK01000012_gene375	7.33e-138	443.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yqfU	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_7694129_0	1405.DJ92_650	4.606e-247	773.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yfkN_2	-	3.1.3.5,3.1.3.6,3.1.4.16	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HKD3_k127_7694129_2	1396.DJ87_1234	1.343e-52	188.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,1ZE0C@1386|Bacillus	91061|Bacilli	P	Phosphonate ABC transporter	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
HKD3_k127_7700075_2	1034769.KB910518_gene4574	6.259e-93	316.0	COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,26QHQ@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	desK	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
HKD3_k127_7700075_3	1405.DJ92_2447	1.208e-92	310.0	COG0842@1|root,COG0842@2|Bacteria,1V7QG@1239|Firmicutes,4HFU4@91061|Bacilli,1ZD2I@1386|Bacillus	91061|Bacilli	V	COG0842 ABC-type multidrug transport system, permease component	XK27_09830	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD3_k127_7700075_1	315749.Bcer98_3874	3.353e-116	381.0	COG1131@1|root,COG1131@2|Bacteria,1TRM5@1239|Firmicutes,4HFBN@91061|Bacilli,1ZCK0@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	yvfR	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_7700075_0	198094.BA_5601	1.458e-129	417.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZCVZ@1386|Bacillus	91061|Bacilli	E	Methionine aminopeptidase	yflG	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD3_k127_7786917_1	471223.GWCH70_2777	2.015e-228	711.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,1WF8Q@129337|Geobacillus	91061|Bacilli	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD3_k127_7786917_0	198094.BA_5019	2.325e-293	906.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus	91061|Bacilli	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09060,iYO844.BSU30560	PEPCK_ATP
HKD3_k127_7786917_2	574376.BAMA_12925	5.82e-144	463.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,1ZC0Z@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	ytlA	GO:0003674,GO:0005215	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
HKD3_k127_7786917_4	1169144.KB910943_gene2303	3.359e-107	352.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HBZ6@91061|Bacilli,1ZC33@1386|Bacillus	91061|Bacilli	P	ABC transporter	ytlC	-	3.6.3.36	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00435,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4	-	-	ABC_tran
HKD3_k127_7786917_3	574376.BAMA_12935	1.229e-114	376.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HARB@91061|Bacilli,1ZD96@1386|Bacillus	91061|Bacilli	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	ytlD3	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD3_k127_7786917_6	1169144.KB910943_gene2299	1.11e-69	239.0	COG0494@1|root,COG0494@2|Bacteria,1V42H@1239|Firmicutes,4HH5W@91061|Bacilli,1ZGYP@1386|Bacillus	91061|Bacilli	L	Belongs to the Nudix hydrolase family	ytkD	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD3_k127_7786917_5	1169144.KB910943_gene2297	5.497e-90	297.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,1ZBSW@1386|Bacillus	91061|Bacilli	T	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
HKD3_k127_7786917_8	1169144.KB910943_gene2296	1.729e-38	144.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,1ZHVV@1386|Bacillus	91061|Bacilli	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD3_k127_7786917_7	315730.BcerKBAB4_4628	8.229e-63	217.0	COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,4HFQA@91061|Bacilli,1ZB5T@1386|Bacillus	91061|Bacilli	P	Reversible hydration of carbon dioxide	ytiB	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD3_k127_7838798_1	1234664.AMRO01000003_gene659	1.291e-61	215.0	COG0500@1|root,COG2226@2|Bacteria,1U9IT@1239|Firmicutes,4HDV5@91061|Bacilli,1WG8D@129337|Geobacillus	91061|Bacilli	Q	Methionine biosynthesis protein MetW	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD3_k127_7838798_0	1405.DJ92_4697	1.141e-298	922.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,1ZCFH@1386|Bacillus	91061|Bacilli	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HKD3_k127_7838798_2	574376.BAMA_20035	3.038e-14	74.0	COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,1ZC9I@1386|Bacillus	91061|Bacilli	L	COG0513 Superfamily II DNA and RNA helicases	yfmL	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HKD3_k127_7932209_6	649747.HMPREF0083_02227	4.89e-50	180.0	COG3766@1|root,COG3766@2|Bacteria,1V5FI@1239|Firmicutes,4HI2M@91061|Bacilli,26XVP@186822|Paenibacillaceae	91061|Bacilli	S	Domain of Unknown Function (DUF350)	yjfL	-	-	-	-	-	-	-	-	-	-	-	DUF350
HKD3_k127_7932209_3	574375.BAGA_14645	3.937e-77	261.0	28NZ6@1|root,2ZBW5@2|Bacteria,1V3TC@1239|Firmicutes,4HIDT@91061|Bacilli,1ZMRD@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
HKD3_k127_7932209_4	1405.DJ92_1901	4.219e-77	266.0	COG3266@1|root,COG3266@2|Bacteria,1UZU9@1239|Firmicutes,4HFGM@91061|Bacilli,1ZI0R@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4247)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4247
HKD3_k127_7932209_0	1131730.BAVI_17162	5.462e-130	426.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
HKD3_k127_7932209_1	1405.DJ92_4418	3.899e-121	392.0	COG3384@1|root,COG3384@2|Bacteria,1TSRZ@1239|Firmicutes,4HAAN@91061|Bacilli,1ZBC3@1386|Bacillus	91061|Bacilli	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	DODA	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
HKD3_k127_7932209_2	796606.BMMGA3_09740	4.94e-84	285.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli,1ZBYZ@1386|Bacillus	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD3_k127_7932209_5	315730.BcerKBAB4_5662	9.081e-62	219.0	COG0741@1|root,COG0741@2|Bacteria,1VD4A@1239|Firmicutes,4HN7R@91061|Bacilli,1ZDE7@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yocA	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
HKD3_k127_8045576_2	1117379.BABA_06491	3.003e-111	377.0	COG2199@1|root,COG2199@2|Bacteria,1VAHW@1239|Firmicutes,4HU73@91061|Bacilli,1ZDV2@1386|Bacillus	91061|Bacilli	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HKD3_k127_8045576_0	1196029.ALIM01000020_gene5018	1.218e-297	914.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1ZQ3H@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	bglH	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HKD3_k127_8045576_1	935836.JAEL01000048_gene3656	1.06e-130	419.0	COG1737@1|root,COG1737@2|Bacteria,1TS9A@1239|Firmicutes,4HCBF@91061|Bacilli,1ZAUR@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HKD3_k127_8045576_3	666686.B1NLA3E_07535	6.968e-109	358.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZMI4@1386|Bacillus	91061|Bacilli	C	Electron transfer flavoprotein FAD-binding domain	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Acyl-CoA_dh_1,ETF,ETF_alpha
HKD3_k127_806583_2	1206737.BAGF01000040_gene2145	7.778e-07	53.0	COG4891@1|root,COG4891@2|Bacteria,2ISCT@201174|Actinobacteria,4G58B@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HKD3_k127_806583_1	1284352.AOIG01000013_gene3503	7.491e-62	219.0	COG1309@1|root,COG1309@2|Bacteria,1V5AJ@1239|Firmicutes,4HI7X@91061|Bacilli,26XGU@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
HKD3_k127_806583_0	1078085.HMPREF1210_03093	1.699e-146	466.0	COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,26CZN@186818|Planococcaceae	91061|Bacilli	E	Belongs to the serine threonine dehydratase family. DsdA subfamily	dsdA	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	PALP
HKD3_k127_824274_7	1405.DJ92_2581	4.153e-17	81.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,1ZBYD@1386|Bacillus	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HKD3_k127_824274_5	1169144.KB910926_gene1097	7.729e-44	163.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,1ZHUH@1386|Bacillus	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD3_k127_824274_8	491915.Aflv_2863	7.747e-17	81.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,21VVM@150247|Anoxybacillus	91061|Bacilli	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD3_k127_824274_2	1169144.KB910926_gene1095	2.096e-256	794.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD3_k127_824274_4	574375.BAGA_13740	4.398e-199	625.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,1ZAVV@1386|Bacillus	91061|Bacilli	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
HKD3_k127_824274_6	574375.BAGA_13745	4.488e-29	117.0	COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,1ZIXZ@1386|Bacillus	91061|Bacilli	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
HKD3_k127_824274_3	574375.BAGA_13750	2.995e-202	633.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HKD3_k127_824274_1	574376.BAMA_12595	0.0	1120.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD3_k127_824274_0	574376.BAMA_12590	0.0	1399.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD3_k127_8461213_9	1405.DJ92_1494	4.109e-75	254.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD3_k127_8461213_8	315749.Bcer98_3107	1.272e-90	302.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
HKD3_k127_8461213_1	1169144.KB910936_gene1267	0.0	1227.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus	91061|Bacilli	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
HKD3_k127_8461213_13	406124.ACPC01000019_gene3234	1.184e-30	121.0	2E4YS@1|root,32ZSJ@2|Bacteria,1VEX3@1239|Firmicutes,4HNZ8@91061|Bacilli,1ZIT3@1386|Bacillus	91061|Bacilli	-	-	yrzR	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8461213_4	1169144.KB910936_gene1270	7.111e-163	520.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZBGE@1386|Bacillus	91061|Bacilli	S	AI-2E family transporter	yrrI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD3_k127_8461213_0	315749.Bcer98_3101	0.0	1455.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD3_k127_8461213_12	198094.BA_4615	7.723e-44	161.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,1ZHU7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
HKD3_k127_8461213_11	1169144.KB910936_gene1273	1.394e-65	226.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,1ZG6Y@1386|Bacillus	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD3_k127_8461213_14	574376.BAMA_21740	4.059e-30	122.0	COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,1ZI20@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0473 family	yrzB	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HKD3_k127_8461213_5	1405.DJ92_1483	2.139e-127	417.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,1ZC44@1386|Bacillus	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD3_k127_8461213_7	574376.BAMA_21755	8.151e-91	305.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli,1ZFK8@1386|Bacillus	91061|Bacilli	S	O-methyltransferase	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
HKD3_k127_8461213_3	1169144.KB910936_gene1277	7.969e-166	524.0	COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus	91061|Bacilli	O	Peptidase U32	yrrN	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
HKD3_k127_8461213_2	315749.Bcer98_3094	6.759e-231	719.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli,1ZC7K@1386|Bacillus	91061|Bacilli	O	COG0826 Collagenase and related proteases	yrrO	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HKD3_k127_8461213_6	574376.BAMA_21770	2.551e-110	359.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,1ZB2B@1386|Bacillus	91061|Bacilli	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HKD3_k127_8461213_10	315749.Bcer98_3092	2.038e-74	252.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD3_k127_8461213_15	1405.DJ92_1474	7.288e-20	95.0	2BJ57@1|root,32DEE@2|Bacteria,1V93H@1239|Firmicutes,4HN71@91061|Bacilli,1ZH00@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1510)	yrrS	-	-	-	-	-	-	-	-	-	-	-	DUF1510
HKD3_k127_8462717_3	1382358.JHVN01000025_gene1430	1.077e-172	546.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,21VZA@150247|Anoxybacillus	91061|Bacilli	F	Glutamine phosphoribosylpyrophosphate amidotransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
HKD3_k127_8462717_6	1236973.JCM9157_3408	1.069e-119	391.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_8462717_0	1169144.KB910977_gene739	1.881e-250	776.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0003674,GO:0003824,GO:0004642,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD3_k127_8462717_4	198094.BA_0293	5.323e-124	399.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,1ZB9C@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HKD3_k127_8462717_8	1123226.KB899296_gene411	2.831e-23	101.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,26Z31@186822|Paenibacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
HKD3_k127_8462717_5	1405.DJ92_2914	7.045e-123	397.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,1ZAWJ@1386|Bacillus	91061|Bacilli	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HKD3_k127_8462717_1	1236973.JCM9157_4940	1.983e-249	774.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,1ZC7P@1386|Bacillus	91061|Bacilli	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09895	ADSL_C,Lyase_1
HKD3_k127_8462717_2	574375.BAGA_22825	1.889e-175	556.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,1ZB8P@1386|Bacillus	91061|Bacilli	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
HKD3_k127_8462717_7	1396.DJ87_4700	6.048e-78	262.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HKD3_k127_8462717_9	1382358.JHVN01000023_gene1893	1.827e-10	63.0	29Y0M@1|root,30JTI@2|Bacteria,1V50V@1239|Firmicutes,4HHX7@91061|Bacilli,21WVR@150247|Anoxybacillus	91061|Bacilli	S	Family of unknown function (DUF5317)	M1-582	-	-	-	-	-	-	-	-	-	-	-	DUF5317
HKD3_k127_8467269_1	1396.DJ87_1390	8.13e-47	172.0	COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli,1ZD78@1386|Bacillus	91061|Bacilli	S	-transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
HKD3_k127_8467269_0	1169144.KB910952_gene3175	0.0	1530.0	COG0419@1|root,COG0419@2|Bacteria,1V0XP@1239|Firmicutes,4IS71@91061|Bacilli,1ZEXN@1386|Bacillus	91061|Bacilli	L	Tubulin like	-	-	-	-	-	-	-	-	-	-	-	-	Tubulin_2
HKD3_k127_8474311_5	1178537.BA1_14195	4.136e-55	194.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,1ZB5N@1386|Bacillus	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD3_k127_8474311_2	1295642.H839_16443	1.122e-134	434.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,1WE6H@129337|Geobacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD3_k127_8474311_6	1169144.KB910975_gene2405	3.238e-29	120.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,1ZITU@1386|Bacillus	91061|Bacilli	C	COG2010 Cytochrome c, mono- and diheme variants	cccB	-	-	ko:K12263,ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
HKD3_k127_8474311_4	1423321.AS29_02210	5.478e-93	310.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,1ZCAE@1386|Bacillus	91061|Bacilli	D	cell division ATP-binding protein FtsE	ftsE	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD3_k127_8474311_1	315749.Bcer98_3722	1.038e-141	454.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus	91061|Bacilli	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD3_k127_8474311_0	1169144.KB910975_gene2408	1.534e-218	686.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpB	GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
HKD3_k127_8474311_3	315730.BcerKBAB4_4975	3.653e-118	390.0	COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,1ZAQG@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	minJ	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
HKD3_k127_8484425_0	1405.DJ92_4052	3.95e-212	663.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10700	Aconitase
HKD3_k127_8484425_10	1140003.I573_00127	8.441e-68	235.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,4B0JK@81852|Enterococcaceae	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HKD3_k127_8484425_1	1169144.KB910983_gene3465	1.346e-189	600.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,1ZB4H@1386|Bacillus	91061|Bacilli	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
HKD3_k127_8484425_12	1423806.JCM15457_2444	4.24e-44	168.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,3F4WT@33958|Lactobacillaceae	91061|Bacilli	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,tRNA-synt_His
HKD3_k127_8484425_2	574376.BAMA_13520	1.96e-183	582.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus	91061|Bacilli	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU34910	Histidinol_dh
HKD3_k127_8484425_8	1169144.KB910983_gene3468	4.62e-88	294.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,1ZBVJ@1386|Bacillus	91061|Bacilli	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14130	IGPD
HKD3_k127_8484425_9	1169144.KB910983_gene3469	2.426e-80	273.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,1ZBC4@1386|Bacillus	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD3_k127_8484425_7	748727.CLJU_c11710	2.247e-89	300.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,36FQ2@31979|Clostridiaceae	186801|Clostridia	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD3_k127_8484425_5	1169144.KB910983_gene3471	8.677e-126	406.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,1ZAUX@1386|Bacillus	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14115	His_biosynth
HKD3_k127_8484425_11	1552123.EP57_12140	5.358e-47	170.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,26KNS@186820|Listeriaceae	91061|Bacilli	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
HKD3_k127_8484425_13	1169144.KB910983_gene3473	4.597e-38	145.0	COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,4HPCZ@91061|Bacilli,1ZN88@1386|Bacillus	91061|Bacilli	E	phosphoribosyl-ATP diphosphatase activity	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
HKD3_k127_8484425_3	1169144.KB910983_gene3474	2.285e-156	500.0	COG1387@1|root,COG1387@2|Bacteria,1UZ0M@1239|Firmicutes,4HAUH@91061|Bacilli,1ZE5C@1386|Bacillus	91061|Bacilli	E	COG1387 Histidinol phosphatase and related hydrolases of the PHP family	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HKD3_k127_8484425_4	315730.BcerKBAB4_1337	6.339e-148	474.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,1ZB0I@1386|Bacillus	91061|Bacilli	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD3_k127_8484425_6	1169144.KB910983_gene3477	5.075e-114	372.0	COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HF0K@91061|Bacilli,1ZDC6@1386|Bacillus	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HKD3_k127_8494599_0	1329516.JPST01000029_gene3251	9.734e-115	378.0	COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD3_k127_8494599_1	406124.ACPC01000019_gene2875	3.183e-84	289.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HIE5@91061|Bacilli,1ZR5H@1386|Bacillus	91061|Bacilli	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HKD3_k127_8506325_4	1334046.AYTB01000013_gene480	3.253e-61	213.0	COG2210@1|root,COG2210@2|Bacteria,1V3UE@1239|Firmicutes,4HH93@91061|Bacilli,26F4C@186818|Planococcaceae	91061|Bacilli	S	DsrE/DsrF-like family	perX	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
HKD3_k127_8506325_3	1295642.H839_02111	9.43e-79	267.0	COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1WEGQ@129337|Geobacillus	91061|Bacilli	OP	Belongs to the sulfur carrier protein TusA family	yrkF	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,TusA
HKD3_k127_8506325_0	1295642.H839_02116	9.164e-181	572.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1WEXM@129337|Geobacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_8506325_6	398511.BpOF4_13465	3.926e-30	120.0	COG0425@1|root,COG0425@2|Bacteria,1VEEC@1239|Firmicutes,4HNQT@91061|Bacilli,1ZI1V@1386|Bacillus	91061|Bacilli	O	Belongs to the sulfur carrier protein TusA family	yrkI	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	-	-	-	-	-	-	-	-	-	TusA
HKD3_k127_8506325_1	1297581.H919_12983	4.38e-102	338.0	COG0730@1|root,COG0730@2|Bacteria,1TRIE@1239|Firmicutes,4HARW@91061|Bacilli,21VI9@150247|Anoxybacillus	91061|Bacilli	S	Sulfite exporter TauE/SafE	yrkJ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_8506325_2	1121085.AUCI01000005_gene984	7.676e-87	293.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,1ZB8T@1386|Bacillus	91061|Bacilli	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HKD3_k127_8506325_5	1169144.KB910933_gene4242	2.255e-49	181.0	COG3103@1|root,COG3757@1|root,COG5632@1|root,COG3757@2|Bacteria,COG4991@2|Bacteria,COG5632@2|Bacteria,1V7SE@1239|Firmicutes,4HJQZ@91061|Bacilli,1ZINP@1386|Bacillus	91061|Bacilli	M	Glycosyl hydrolases family 25	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
HKD3_k127_8538786_2	315749.Bcer98_1228	6.862e-39	146.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus	91061|Bacilli	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD3_k127_8538786_3	315749.Bcer98_1229	4.643e-31	124.0	2E36V@1|root,32Y6J@2|Bacteria,1VFDU@1239|Firmicutes,4HY6K@91061|Bacilli,1ZHWX@1386|Bacillus	91061|Bacilli	S	Stage VI sporulation protein F	-	-	-	-	-	-	-	-	-	-	-	-	SpoVIF
HKD3_k127_8538786_0	1169144.KB910925_gene175	2.931e-313	964.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,4HBH1@91061|Bacilli,1ZBNH@1386|Bacillus	91061|Bacilli	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
HKD3_k127_8538786_1	1169144.KB910925_gene174	6.305e-51	181.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZH48@1386|Bacillus	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hbs	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD3_k127_8558964_13	1169144.KB910943_gene2295	1.311e-44	163.0	COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,4HFQA@91061|Bacilli,1ZB5T@1386|Bacillus	91061|Bacilli	P	Reversible hydration of carbon dioxide	ytiB	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD3_k127_8558964_2	1169144.KB910943_gene2294	6.832e-242	752.0	COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus	91061|Bacilli	C	oxidase, subunit	cydA2	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
HKD3_k127_8558964_11	1304888.ATWF01000001_gene886	4.822e-91	310.0	COG1294@1|root,COG1294@2|Bacteria,2GF3K@200930|Deferribacteres	200930|Deferribacteres	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
HKD3_k127_8558964_6	1121090.KB894689_gene376	3.603e-137	445.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus	91061|Bacilli	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD3_k127_8558964_3	574376.BAMA_11900	4.075e-205	649.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus	91061|Bacilli	H	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_8558964_5	1169144.KB910943_gene2266	1.95e-163	516.0	COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,1ZB3B@1386|Bacillus	91061|Bacilli	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD3_k127_8558964_10	574375.BAGA_14390	9.479e-103	342.0	COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus	91061|Bacilli	S	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	GO:0003674,GO:0003824,GO:0016787	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
HKD3_k127_8558964_1	1405.DJ92_1940	1.533e-245	770.0	COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus	91061|Bacilli	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05085	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
HKD3_k127_8558964_4	1169144.KB910943_gene2263	2.019e-165	532.0	COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,4H9K8@91061|Bacilli,1ZB3V@1386|Bacillus	91061|Bacilli	HQ	Isochorismate synthase	menF	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30830	Chorismate_bind
HKD3_k127_8558964_7	1405.DJ92_1942	2.105e-135	437.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,1ZB6F@1386|Bacillus	91061|Bacilli	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD3_k127_8558964_12	1405.DJ92_1943	1.117e-88	303.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,1ZEEI@1386|Bacillus	91061|Bacilli	T	COG1734 DnaK suppressor protein	yteA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
HKD3_k127_8558964_14	574376.BAMA_11950	1.094e-33	131.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZI6D@1386|Bacillus	91061|Bacilli	K	cold-shock protein	cspC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD3_k127_8558964_8	574376.BAMA_11955	8.01e-134	429.0	COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,4H9P0@91061|Bacilli,1ZERN@1386|Bacillus	91061|Bacilli	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HKD3_k127_8558964_9	574376.BAMA_11960	1.671e-104	344.0	COG3675@1|root,COG3675@2|Bacteria,1VFNV@1239|Firmicutes,4IRGC@91061|Bacilli,1ZGP6@1386|Bacillus	91061|Bacilli	I	Lipase (class 3)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
HKD3_k127_8558964_0	1169144.KB910943_gene2257	0.0	1285.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus	91061|Bacilli	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	iYO844.BSU30940	Phosphorylase
HKD3_k127_8576274_0	1122915.AUGY01000074_gene4331	4.2e-194	615.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,26S9B@186822|Paenibacillaceae	91061|Bacilli	V	MatE	matE	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD3_k127_8576274_3	1169144.KB910935_gene2004	5.337e-92	310.0	COG0561@1|root,COG0561@2|Bacteria,1VAM3@1239|Firmicutes,4HMW6@91061|Bacilli,1ZQ4D@1386|Bacillus	91061|Bacilli	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HKD3_k127_8576274_2	634956.Geoth_2205	4.007e-125	404.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1WF4C@129337|Geobacillus	91061|Bacilli	E	generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD3_k127_8576274_1	1405.DJ92_2821	4.363e-130	425.0	COG0842@1|root,COG0842@2|Bacteria,1V7HN@1239|Firmicutes,4HGE5@91061|Bacilli,1ZCVY@1386|Bacillus	91061|Bacilli	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD3_k127_8576274_4	315749.Bcer98_0216	1.04e-89	302.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1V8HM@1239|Firmicutes,4IPM5@91061|Bacilli,1ZRCG@1386|Bacillus	91061|Bacilli	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD3_k127_8578245_0	441769.ABFU01000013_gene2518	0.0	1166.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,1ZBSM@1386|Bacillus	91061|Bacilli	G	Glycoside hydrolase, family 65	mapA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
HKD3_k127_8578245_10	1169144.KB910924_gene571	0.0006911	42.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	malR	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
HKD3_k127_8578245_2	1408303.JNJJ01000040_gene4400	1.101e-258	808.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus	91061|Bacilli	G	Alpha amylase, N-terminal ig-like domain	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N,Malt_amylase_C
HKD3_k127_8578245_3	574376.BAMA_17255	2.805e-194	612.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus	91061|Bacilli	P	Ammonium transporter	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iYO844.BSU36510	Ammonium_transp
HKD3_k127_8578245_6	1423321.AS29_18690	1.73e-53	190.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HM5G@91061|Bacilli,1ZGHT@1386|Bacillus	91061|Bacilli	K	Belongs to the P(II) protein family	nrgB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HKD3_k127_8578245_1	1169144.KB910927_gene1363	0.0	1020.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,1ZBY8@1386|Bacillus	91061|Bacilli	E	Asparagine synthase	asnO	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD3_k127_8578245_5	574376.BAMA_17240	2.895e-55	199.0	2E4ZB@1|root,32ZT1@2|Bacteria,1VHAC@1239|Firmicutes,4HQBP@91061|Bacilli,1ZD5D@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2777)	yisN	-	-	-	-	-	-	-	-	-	-	-	DUF2777
HKD3_k127_8578245_4	574376.BAMA_17215	3.036e-120	392.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus	91061|Bacilli	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	yisK	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD3_k127_8578245_7	1169144.KB910927_gene1370	3.005e-28	114.0	2DPJX@1|root,332FH@2|Bacteria,1VF9T@1239|Firmicutes,4HPCA@91061|Bacilli,1ZIV2@1386|Bacillus	91061|Bacilli	S	Spore germination protein	gerPA	GO:0000003,GO:0008150,GO:0009847,GO:0019954,GO:0030436,GO:0032502,GO:0043934	-	ko:K06299	-	-	-	-	ko00000	-	-	-	gerPA
HKD3_k127_8578245_8	574376.BAMA_17200	1.006e-22	99.0	2EBHF@1|root,335HY@2|Bacteria,1VHMW@1239|Firmicutes,4HPZZ@91061|Bacilli,1ZIW2@1386|Bacillus	91061|Bacilli	S	cell differentiation	gerPB	-	-	ko:K06300	-	-	-	-	ko00000	-	-	-	GerPB
HKD3_k127_8594619_47	574376.BAMA_09720	1.963e-55	198.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,4HFTI@91061|Bacilli,1ZBVY@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein AA	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
HKD3_k127_8594619_19	1405.DJ92_1167	7.565e-133	426.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HC42@91061|Bacilli,1ZANZ@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_8594619_36	315730.BcerKBAB4_3904	1.211e-78	263.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,4HGYN@91061|Bacilli,1ZFKS@1386|Bacillus	91061|Bacilli	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
HKD3_k127_8594619_49	315749.Bcer98_2773	6.874e-54	192.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus	91061|Bacilli	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
HKD3_k127_8594619_9	1405.DJ92_1170	7.58e-185	585.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacF	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD3_k127_8594619_51	574376.BAMA_09785	9.925e-47	173.0	COG1846@1|root,COG1846@2|Bacteria,1VJFP@1239|Firmicutes,4HQIH@91061|Bacilli,1ZRR9@1386|Bacillus	91061|Bacilli	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD3_k127_8594619_46	574376.BAMA_09790	8.189e-56	202.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4HH35@91061|Bacilli,1ZGZ6@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF541)	bp26	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
HKD3_k127_8594619_15	1169144.KB910924_gene640	1.994e-144	463.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus	91061|Bacilli	P	Mediates influx of magnesium ions	corA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	iYO844.BSU08000	CorA
HKD3_k127_8594619_5	315749.Bcer98_2784	6.234e-222	693.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus	91061|Bacilli	F	phosphorylase	deoA	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HKD3_k127_8594619_22	574376.BAMA_09810	4e-130	419.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HKD3_k127_8594619_4	574376.BAMA_09815	1.106e-222	693.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus	91061|Bacilli	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
HKD3_k127_8594619_37	1169144.KB910924_gene644	6.493e-77	264.0	28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus	91061|Bacilli	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
HKD3_k127_8594619_14	1405.DJ92_1184	2.114e-146	467.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus	91061|Bacilli	L	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD3_k127_8594619_56	574375.BAGA_01960	4.948e-22	98.0	2E9B4@1|root,333IZ@2|Bacteria,1VHUQ@1239|Firmicutes,4HR2C@91061|Bacilli,1ZIY4@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4227)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4227
HKD3_k127_8594619_34	1169144.KB910924_gene647	1.968e-80	269.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,4HH78@91061|Bacilli,1ZCPG@1386|Bacillus	91061|Bacilli	P	Belongs to the Fur family	fur	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD3_k127_8594619_29	1169144.KB910924_gene648	1.457e-90	302.0	COG1300@1|root,COG1300@2|Bacteria,1V81P@1239|Firmicutes,4HJW8@91061|Bacilli,1ZAYC@1386|Bacillus	91061|Bacilli	S	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane	spoIIM	GO:0005575,GO:0005623,GO:0008150,GO:0010564,GO:0022603,GO:0030428,GO:0032465,GO:0032467,GO:0032954,GO:0042173,GO:0043937,GO:0044087,GO:0044089,GO:0044464,GO:0045595,GO:0045787,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051130,GO:0051302,GO:0051726,GO:0051781,GO:0065007,GO:0090068,GO:1901891,GO:1901893	-	ko:K06384	-	-	-	-	ko00000	-	-	-	SpoIIM
HKD3_k127_8594619_43	574376.BAMA_09845	2.687e-59	211.0	COG1670@1|root,COG1670@2|Bacteria,1V26J@1239|Firmicutes,4HG0M@91061|Bacilli,1ZMCR@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD3_k127_8594619_38	574376.BAMA_09850	7.443e-77	261.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,1ZFIW@1386|Bacillus	91061|Bacilli	L	Belongs to the Nudix hydrolase family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
HKD3_k127_8594619_18	1405.DJ92_1191	7.077e-134	432.0	COG0667@1|root,COG0667@2|Bacteria,1TTT8@1239|Firmicutes,4H9XM@91061|Bacilli,1ZBYV@1386|Bacillus	91061|Bacilli	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	yqkF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD3_k127_8594619_59	1196029.ALIM01000014_gene3069	2.743e-10	66.0	2EGUT@1|root,33AKY@2|Bacteria,1VKYE@1239|Firmicutes,4HRB5@91061|Bacilli,1ZJ1Z@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3886)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3886
HKD3_k127_8594619_3	1169144.KB910924_gene658	7.328e-238	745.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01081,ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,CW_binding_1,Gram_pos_anchor,Metallophos,SLH
HKD3_k127_8594619_44	574375.BAGA_02035	8.611e-58	212.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,1ZC3W@1386|Bacillus	91061|Bacilli	K	transcriptional	rbsR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD3_k127_8594619_24	574376.BAMA_09910	2.904e-125	407.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HIXR@91061|Bacilli,1ZQZI@1386|Bacillus	91061|Bacilli	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
HKD3_k127_8594619_57	1267580.AF6_1005	6.194e-21	94.0	2FH9Z@1|root,34949@2|Bacteria,1VYS1@1239|Firmicutes,4HYMH@91061|Bacilli,21X5F@150247|Anoxybacillus	91061|Bacilli	S	Protein of unknown function (DUF2552)	yqkC	-	-	-	-	-	-	-	-	-	-	-	DUF2552
HKD3_k127_8594619_55	198467.NP92_10405	1.173e-27	113.0	COG3369@1|root,COG3369@2|Bacteria,1VFK3@1239|Firmicutes,4HNHY@91061|Bacilli,21VWE@150247|Anoxybacillus	91061|Bacilli	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
HKD3_k127_8594619_53	1347369.CCAD010000090_gene1875	1.144e-30	124.0	COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,1ZIV0@1386|Bacillus	91061|Bacilli	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD3_k127_8594619_54	1169144.KB910924_gene669	2.631e-29	121.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,4HNI0@91061|Bacilli,1ZJ3M@1386|Bacillus	91061|Bacilli	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD3_k127_8594619_11	1169144.KB910924_gene670	3.786e-160	512.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,1ZBTJ@1386|Bacillus	91061|Bacilli	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD3_k127_8594619_40	1382315.JPOI01000001_gene1980	3.249e-66	232.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,1WFKI@129337|Geobacillus	91061|Bacilli	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08950,iYO844.BSU23270	Lum_binding
HKD3_k127_8594619_6	1396.DJ87_744	1.367e-209	656.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,1ZBF9@1386|Bacillus	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
HKD3_k127_8594619_33	574376.BAMA_09950	6.488e-81	271.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,1ZFJ6@1386|Bacillus	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
HKD3_k127_8594619_7	1169144.KB910924_gene675	2.238e-192	602.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,4HAGM@91061|Bacilli,1ZCAU@1386|Bacillus	91061|Bacilli	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30200	BATS,Radical_SAM
HKD3_k127_8594619_32	1236973.JCM9157_1476	5.763e-84	284.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,1ZBSK@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF554)	ydfK	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
HKD3_k127_8594619_42	1121090.KB894687_gene809	1.257e-59	211.0	COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli,1ZFRS@1386|Bacillus	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	yhcS	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HKD3_k127_8594619_2	1396.DJ87_733	1.531e-251	797.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Cu_amine_oxidN1,Gram_pos_anchor,LysM,Metallophos,SLH
HKD3_k127_8594619_52	260799.BAS4033	1.398e-46	171.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4HIMR@91061|Bacilli,1ZK1I@1386|Bacillus	91061|Bacilli	K	Winged helix DNA-binding domain	XK27_02735	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD3_k127_8594619_45	1131730.BAVI_01869	1.312e-56	205.0	COG3216@1|root,COG3216@2|Bacteria,1VG1T@1239|Firmicutes,4HNPX@91061|Bacilli,1ZE24@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
HKD3_k127_8594619_20	1405.DJ92_1227	9.993e-133	429.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,1ZC5E@1386|Bacillus	91061|Bacilli	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD3_k127_8594619_12	235909.GK0793	5.726e-155	499.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,1WF3K@129337|Geobacillus	91061|Bacilli	E	Aminotransferase class-III	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD3_k127_8594619_30	1405.DJ92_1229	1.287e-88	299.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,1ZF3H@1386|Bacillus	91061|Bacilli	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD3_k127_8594619_10	634956.Geoth_3072	4.92e-169	541.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1WG02@129337|Geobacillus	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HKD3_k127_8594619_60	796606.BMMGA3_11205	4.666e-08	56.0	2BZSR@1|root,2ZFSH@2|Bacteria,1W2MW@1239|Firmicutes	1239|Firmicutes	S	YqzH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YqzH
HKD3_k127_8594619_28	260799.BAS4042	1.523e-104	345.0	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,1ZBRZ@1386|Bacillus	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HKD3_k127_8594619_17	1405.DJ92_1234	6.715e-134	433.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqjP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_8594619_26	574376.BAMA_10045	1.14e-110	364.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD3_k127_8594619_13	1169144.KB910924_gene691	1.279e-150	481.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus	91061|Bacilli	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
HKD3_k127_8594619_16	574376.BAMA_10075	2.177e-142	465.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,1ZAZZ@1386|Bacillus	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD3_k127_8594619_8	1033734.CAET01000077_gene2924	9.559e-190	598.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus	91061|Bacilli	E	COG2195 Di- and tripeptidases	yqjE	-	3.4.11.14,3.4.11.4	ko:K01258,ko:K01263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD3_k127_8594619_1	1382358.JHVN01000001_gene814	2.091e-287	887.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,21W6K@150247|Anoxybacillus	91061|Bacilli	I	Carboxyl transferase domain	yqjD	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD3_k127_8594619_48	1131730.BAVI_21408	4.072e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4HCP5@91061|Bacilli,1ZHE7@1386|Bacillus	91061|Bacilli	E	COG0346 Lactoylglutathione lyase and related lyases	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HKD3_k127_8594619_35	574375.BAGA_02265	1.857e-79	268.0	COG1376@1|root,COG1376@2|Bacteria,1V26F@1239|Firmicutes,4HG56@91061|Bacilli,1ZGC7@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yqjB	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD3_k127_8594619_23	471223.GWCH70_2289	3.051e-127	409.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1WG7Q@129337|Geobacillus	91061|Bacilli	E	ATPases associated with a variety of cellular activities	artM	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HKD3_k127_8594619_41	91604.ID47_03315	1.073e-61	219.0	COG0765@1|root,COG0765@2|Bacteria,1N786@1224|Proteobacteria,2TRW3@28211|Alphaproteobacteria,47GQG@766|Rickettsiales	766|Rickettsiales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HKD3_k127_8594619_27	1169144.KB910924_gene701	1.327e-104	345.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli,1ZQ0V@1386|Bacillus	91061|Bacilli	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD3_k127_8594619_31	1405.DJ92_3428	8.262e-86	290.0	COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,4HEBS@91061|Bacilli,1ZCY4@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigI	-	-	ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
HKD3_k127_8594619_39	1403313.AXBR01000007_gene476	1.522e-74	252.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZFKZ@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HKD3_k127_8594619_21	1267580.AF6_0964	2.255e-131	428.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H9ZJ@91061|Bacilli,21VBT@150247|Anoxybacillus	91061|Bacilli	E	Conserved hypothetical ATP binding protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HKD3_k127_8594619_0	198467.NP92_10310	0.0	1132.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,21WQU@150247|Anoxybacillus	91061|Bacilli	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
HKD3_k127_8594619_25	1200792.AKYF01000010_gene2176	2.523e-118	404.0	COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,271U2@186822|Paenibacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HKD3_k127_8594619_50	574375.BAGA_02300	7.572e-48	173.0	COG1051@1|root,COG1051@2|Bacteria,1V6Q0@1239|Firmicutes,4HIKK@91061|Bacilli,1ZH3B@1386|Bacillus	91061|Bacilli	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD3_k127_8607905_3	198094.BA_1532	2.539e-108	351.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,1ZAZD@1386|Bacillus	91061|Bacilli	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD3_k127_8607905_5	574376.BAMA_14030	8.735e-65	229.0	COG0142@1|root,COG0142@2|Bacteria,1V1TG@1239|Firmicutes,4HIBX@91061|Bacilli,1ZETD@1386|Bacillus	91061|Bacilli	H	heptaprenyl diphosphate synthase	hepS	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	HEPPP_synt_1
HKD3_k127_8607905_1	1169144.KB910925_gene171	1.196e-130	419.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,1ZB6U@1386|Bacillus	91061|Bacilli	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HKD3_k127_8607905_0	574376.BAMA_14040	9.263e-161	511.0	COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,1ZAZ7@1386|Bacillus	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	hepT	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.30,2.5.1.83	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	-	R09245,R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD3_k127_8607905_4	420246.GTNG_2143	2.315e-78	263.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,1WF2N@129337|Geobacillus	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HKD3_k127_8607905_2	315749.Bcer98_1240	9.106e-128	417.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,1ZC9C@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD3_k127_8610297_3	1173028.ANKO01000250_gene2400	4.037e-53	191.0	2BWTW@1|root,315N7@2|Bacteria,1G5TV@1117|Cyanobacteria,1HB33@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8610297_0	1173028.ANKO01000250_gene2401	4.627e-165	526.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1H93R@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
HKD3_k127_8610297_2	653733.Selin_2472	1.295e-88	300.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
HKD3_k127_8610297_1	56780.SYN_00820	2.456e-112	373.0	COG0438@1|root,COG0438@2|Bacteria,1PEGM@1224|Proteobacteria,43AEB@68525|delta/epsilon subdivisions,2X5U6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD3_k127_8610297_4	1449063.JMLS01000036_gene6371	6.62e-37	143.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
HKD3_k127_8616559_1	1384049.CD29_01790	6.068e-254	787.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4H9V9@91061|Bacilli,3IW54@400634|Lysinibacillus	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
HKD3_k127_8616559_7	1444310.JANV01000039_gene1137	4.508e-24	110.0	COG1633@1|root,COG4902@1|root,COG1633@2|Bacteria,COG4902@2|Bacteria,1V9AF@1239|Firmicutes,4HIP7@91061|Bacilli,1ZGFE@1386|Bacillus	91061|Bacilli	S	Rubrerythrin	yhjR	-	-	-	-	-	-	-	-	-	-	-	DUF2202,Ferritin_2,Rubrerythrin
HKD3_k127_8616559_3	1243664.CAVL020000015_gene1865	1.04e-69	254.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,1ZS4A@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	yclK	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD3_k127_8616559_4	1169144.KB910964_gene2918	8.12e-68	238.0	COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,1ZD4W@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yclJ	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD3_k127_8616559_2	44251.PDUR_27025	5.314e-132	426.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HE64@91061|Bacilli,26XA9@186822|Paenibacillaceae	91061|Bacilli	EG	transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD3_k127_8616559_5	1196323.ALKF01000203_gene3796	3.179e-49	179.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,4HIJS@91061|Bacilli,26YAX@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11965,iYO844.BSU36660	Urease_gamma
HKD3_k127_8616559_6	1345697.M493_09940	8.961e-49	175.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,4HM0I@91061|Bacilli,1WGI9@129337|Geobacillus	91061|Bacilli	E	Urease beta subunit	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
HKD3_k127_8616559_0	1295642.H839_06854	0.0	998.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,4HBTS@91061|Bacilli,1WEDN@129337|Geobacillus	91061|Bacilli	E	Urease alpha-subunit, N-terminal domain	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
HKD3_k127_8616559_8	1159488.SEQMU2_10705	4.96e-16	78.0	COG2371@1|root,COG2371@2|Bacteria,1V4BI@1239|Firmicutes,4HHMD@91061|Bacilli,4GXNR@90964|Staphylococcaceae	91061|Bacilli	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
HKD3_k127_8619623_11	1307436.PBF_21878	3.394e-06	49.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,1ZB92@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HKD3_k127_8619623_0	315730.BcerKBAB4_0246	1.06e-310	956.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,1ZBKJ@1386|Bacillus	91061|Bacilli	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD3_k127_8619623_8	265729.GS18_0215145	3.22e-47	170.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,1ZGZ1@1386|Bacillus	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD3_k127_8619623_5	1405.DJ92_2878	6.847e-83	281.0	COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,1ZBE1@1386|Bacillus	91061|Bacilli	S	CAAX protease self-immunity	ydiL	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD3_k127_8619623_3	1169144.KB910992_gene2871	3.818e-112	366.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,1ZANM@1386|Bacillus	91061|Bacilli	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HKD3_k127_8619623_1	574375.BAGA_24815	1.682e-299	929.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD3_k127_8619623_2	1405.DJ92_2874	2.964e-186	586.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,1ZBT3@1386|Bacillus	91061|Bacilli	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD3_k127_8619623_6	1405.DJ92_2873	5.178e-61	213.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,1ZGAT@1386|Bacillus	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
HKD3_k127_8619623_4	1169144.KB910992_gene2875	7.522e-94	313.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,1ZC43@1386|Bacillus	91061|Bacilli	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD3_k127_8619623_7	1121091.AUMP01000054_gene3369	5.96e-60	211.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli	91061|Bacilli	M	ATPase or kinase	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD3_k127_8619623_9	1121090.KB894693_gene2511	2.725e-17	81.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8625341_1	1169144.KB910953_gene3162	1.364e-87	296.0	COG0631@1|root,COG0631@2|Bacteria,1V9VA@1239|Firmicutes,4HJDH@91061|Bacilli,1ZG0X@1386|Bacillus	91061|Bacilli	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
HKD3_k127_8625341_0	1405.DJ92_1788	4.88e-140	454.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HC4S@91061|Bacilli,1ZQZX@1386|Bacillus	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HKD3_k127_8625341_2	574376.BAMA_03440	1.352e-78	267.0	COG0477@1|root,COG2814@2|Bacteria,1TSFM@1239|Firmicutes,4HABN@91061|Bacilli,1ZS92@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	yqjV	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
HKD3_k127_8634999_0	471223.GWCH70_1150	0.0	1681.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1WFCA@129337|Geobacillus	91061|Bacilli	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD3_k127_8634999_1	315749.Bcer98_2471	3.307e-301	930.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,1ZD7M@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
HKD3_k127_8634999_2	574376.BAMA_08455	1.414e-203	640.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,1ZCPQ@1386|Bacillus	91061|Bacilli	M	zinc metalloprotease	rasP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
HKD3_k127_8634999_3	1396.DJ87_1110	4.141e-192	605.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,1ZC3I@1386|Bacillus	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
HKD3_k127_8634999_10	315749.Bcer98_2474	1.153e-114	377.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,1ZBWF@1386|Bacillus	91061|Bacilli	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
HKD3_k127_8634999_8	315749.Bcer98_2475	1.031e-129	419.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,1ZC2T@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD3_k127_8634999_11	1169144.KB910924_gene386	1.799e-91	303.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,1ZAZF@1386|Bacillus	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD3_k127_8634999_6	1033734.CAET01000016_gene4210	2.897e-137	439.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus	91061|Bacilli	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
HKD3_k127_8634999_4	1405.DJ92_913	1.528e-150	480.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,1ZB7R@1386|Bacillus	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD3_k127_8634999_5	1169144.KB910924_gene389	2.805e-138	446.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,1ZAYU@1386|Bacillus	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HKD3_k127_8634999_7	315749.Bcer98_2480	5.45e-136	436.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli,1ZBT9@1386|Bacillus	91061|Bacilli	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
HKD3_k127_8634999_9	1169144.KB910924_gene391	6.753e-126	405.0	COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus	91061|Bacilli	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
HKD3_k127_8635778_3	1123290.AUDQ01000007_gene2056	3.001e-58	206.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HCEP@91061|Bacilli	91061|Bacilli	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HKD3_k127_8635778_0	1169144.KB910926_gene1163	8.042e-171	540.0	COG1277@1|root,COG1277@2|Bacteria,1TRV1@1239|Firmicutes,4HBBV@91061|Bacilli,1ZE79@1386|Bacillus	91061|Bacilli	S	ABC transporter (permease)	bcrB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD3_k127_8635778_2	1196324.A374_08064	2.127e-101	338.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD3_k127_8635778_1	198094.BA_5651	6.26e-105	347.0	COG2755@1|root,COG2755@2|Bacteria,1UZKM@1239|Firmicutes,4HD6X@91061|Bacilli,1ZCPP@1386|Bacillus	91061|Bacilli	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD3_k127_8635778_4	1169144.KB910926_gene1158	4.774e-08	55.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,1ZBK1@1386|Bacillus	91061|Bacilli	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06620	GHMP_kinases_C,GHMP_kinases_N
HKD3_k127_86486_2	574375.BAGA_03245	5.597e-29	117.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,4HBY2@91061|Bacilli,1ZB3Q@1386|Bacillus	91061|Bacilli	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD3_k127_86486_1	649747.HMPREF0083_03499	3.545e-128	412.0	COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,4HC2H@91061|Bacilli,26YDB@186822|Paenibacillaceae	91061|Bacilli	L	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
HKD3_k127_86486_0	649747.HMPREF0083_03498	2.023e-147	470.0	COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,4HDBE@91061|Bacilli,26XYK@186822|Paenibacillaceae	91061|Bacilli	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
HKD3_k127_8687209_3	748727.CLJU_c07860	1.15e-81	276.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes	1239|Firmicutes	I	membrane transporter protein	ydhB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD3_k127_8687209_1	1196322.A370_01314	1.143e-149	480.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,36DDS@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD3_k127_8687209_0	1405.DJ92_2381	7.406e-287	887.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZKZJ@1386|Bacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	alkK	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD3_k127_8687209_2	665959.HMPREF1013_03139	8.537e-105	344.0	COG0788@1|root,COG0788@2|Bacteria,1TSN4@1239|Firmicutes,4HAW2@91061|Bacilli,1ZAYE@1386|Bacillus	91061|Bacilli	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
HKD3_k127_8809280_2	1385510.N781_09475	1.056e-07	61.0	COG4709@1|root,COG4709@2|Bacteria,1VBDQ@1239|Firmicutes,4HM00@91061|Bacilli,2YAUJ@289201|Pontibacillus	91061|Bacilli	S	Protein of unknown function (DUF1700)	XK27_04830	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HKD3_k127_8809280_0	315749.Bcer98_3954	5.751e-175	552.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,1ZCC5@1386|Bacillus	91061|Bacilli	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HKD3_k127_8809280_1	1395587.P364_0109095	4.429e-24	102.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,26SK4@186822|Paenibacillaceae	91061|Bacilli	KL	ATP-dependent helicase	uvrB3	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
HKD3_k127_8823259_17	1444309.JAQG01000015_gene1610	4.417e-54	196.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,26SGR@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD3_k127_8823259_11	1169144.KB910937_gene1060	6.27e-86	288.0	COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,1ZD7H@1386|Bacillus	91061|Bacilli	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD3_k127_8823259_13	315749.Bcer98_3213	1.045e-73	256.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	vanYB	-	3.4.16.4,3.4.17.14	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
HKD3_k127_8823259_15	1405.DJ92_1600	5.875e-57	201.0	COG0824@1|root,COG0824@2|Bacteria,1V6GS@1239|Firmicutes,4HJ05@91061|Bacilli,1ZH3F@1386|Bacillus	91061|Bacilli	S	thioesterase	ysmA	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD3_k127_8823259_5	1211814.CAPG01000051_gene2633	1.999e-150	477.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,1ZAPQ@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhB	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
HKD3_k127_8823259_0	1169144.KB910928_gene1928	0.0	1056.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05640	FAD_binding_2,Succ_DH_flav_C
HKD3_k127_8823259_9	1396.DJ87_356	1.311e-102	337.0	COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,1ZBB5@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iYO844.BSU28450	Sdh_cyt
HKD3_k127_8823259_19	574376.BAMA_02840	1.756e-48	177.0	COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,1ZH1A@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2507)	yslB	-	-	-	-	-	-	-	-	-	-	-	DUF2507
HKD3_k127_8823259_1	574375.BAGA_04100	5e-324	997.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,1ZBY1@1386|Bacillus	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD3_k127_8823259_18	1169144.KB910928_gene1940	6.189e-50	179.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,1ZGXM@1386|Bacillus	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD3_k127_8823259_4	574375.BAGA_04110	1.241e-168	534.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus	91061|Bacilli	C	Electron transfer flavoprotein	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HKD3_k127_8823259_6	1405.DJ92_1616	9.961e-132	424.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4H9QY@91061|Bacilli,1ZBTA@1386|Bacillus	91061|Bacilli	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD3_k127_8823259_8	1169144.KB910928_gene1943	1.991e-107	355.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,1ZCKH@1386|Bacillus	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	fadB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HKD3_k127_8823259_10	1169144.KB910928_gene1944	2.98e-98	323.0	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,1ZAU5@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	fadR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
HKD3_k127_8823259_2	1169144.KB910928_gene1945	2.915e-275	855.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HKD3_k127_8823259_12	35841.BT1A1_3153	1.299e-80	279.0	COG3786@1|root,COG3786@2|Bacteria,1VA00@1239|Firmicutes,4HH8T@91061|Bacilli,1ZD3J@1386|Bacillus	91061|Bacilli	F	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,SH3_3,YkuD
HKD3_k127_8823259_16	1117379.BABA_24345	7.412e-57	206.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,4HCJV@91061|Bacilli,1ZAPF@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigD	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD3_k127_8823259_14	1117108.PAALTS15_26524	4.602e-61	220.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,4HCWZ@91061|Bacilli,26R9C@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the ParA family	ylxH	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
HKD3_k127_8823259_7	1117379.BABA_24355	7.669e-110	366.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1ZCJ9@1386|Bacillus	91061|Bacilli	N	Flagellar biosynthesis regulator FlhF	flhF	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
HKD3_k127_8823259_3	621372.ACIH01000014_gene2093	2.958e-188	598.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,26RFY@186822|Paenibacillaceae	91061|Bacilli	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
HKD3_k127_8825881_1	574376.BAMA_16910	6.928e-66	243.0	COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus	91061|Bacilli	S	Membrane	ydbT	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
HKD3_k127_8825881_2	268407.PWYN_12925	2.976e-63	224.0	COG2085@1|root,COG2085@2|Bacteria,1V35D@1239|Firmicutes,4HFSW@91061|Bacilli	91061|Bacilli	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
HKD3_k127_8825881_3	1348908.KI518643_gene166	1.355e-61	222.0	COG0583@1|root,COG0583@2|Bacteria,1V91T@1239|Firmicutes,4HMHT@91061|Bacilli,1ZFCX@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD3_k127_8825881_4	477641.MODMU_2824	2.579e-59	216.0	COG2267@1|root,COG2267@2|Bacteria,2I4BW@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HKD3_k127_8825881_0	1499680.CCFE01000011_gene696	2.685e-96	316.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,1ZCAN@1386|Bacillus	91061|Bacilli	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HKD3_k127_8851025_5	1169144.KB910943_gene2257	9.215e-26	107.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus	91061|Bacilli	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	iYO844.BSU30940	Phosphorylase
HKD3_k127_8851025_1	574375.BAGA_14330	3.923e-240	749.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus	91061|Bacilli	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HKD3_k127_8851025_4	1169144.KB910943_gene2255	9.786e-147	471.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,1ZBVM@1386|Bacillus	91061|Bacilli	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD3_k127_8851025_3	1347086.CCBA010000031_gene1010	5.599e-171	543.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,1ZCF2@1386|Bacillus	91061|Bacilli	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD3_k127_8851025_0	1169144.KB910943_gene2253	0.0	1046.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,1ZCHU@1386|Bacillus	91061|Bacilli	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HKD3_k127_8851025_2	574375.BAGA_14300	3.116e-177	558.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZD2C@1386|Bacillus	91061|Bacilli	C	Belongs to the LDH MDH superfamily. LDH family	ldh	GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HKD3_k127_8851025_6	935837.JAEK01000042_gene3832	5.894e-08	54.0	2DIA4@1|root,302HW@2|Bacteria,1U5Y3@1239|Firmicutes,4IM9X@91061|Bacilli,1ZJJZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8851025_7	1347087.CBYO010000014_gene2137	1.51e-07	52.0	2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_8971611_4	574376.BAMA_12215	6.2e-58	203.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,1ZGZ7@1386|Bacillus	91061|Bacilli	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
HKD3_k127_8971611_0	315749.Bcer98_0067	8.62e-136	437.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD3_k127_8971611_2	315730.BcerKBAB4_0066	6.564e-111	365.0	COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus	91061|Bacilli	EH	4-amino-4-deoxychorismate lyase	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
HKD3_k127_8971611_3	1380408.AVGH01000044_gene1359	1.651e-99	327.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,21V6S@150247|Anoxybacillus	91061|Bacilli	EH	Peptidase C26	pabA	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01664	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	iYO844.BSU00750	GATase
HKD3_k127_8971611_1	1169144.KB910956_gene4103	1.315e-125	404.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus	91061|Bacilli	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD3_k127_8993348_7	1169144.KB910924_gene598	6.854e-100	329.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,1ZBSG@1386|Bacillus	91061|Bacilli	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	glxR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
HKD3_k127_8993348_17	1169144.KB910924_gene602	1.949e-05	49.0	29TJV@1|root,30ET6@2|Bacteria,1UCXV@1239|Firmicutes,4IPDT@91061|Bacilli,1ZPS4@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3915
HKD3_k127_8993348_13	441769.ABFU01000060_gene692	1.507e-42	157.0	COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,1ZQGJ@1386|Bacillus	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
HKD3_k127_8993348_1	1033734.CAET01000022_gene1272	1.051e-277	863.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HKD3_k127_8993348_14	1396.DJ87_808	4.625e-39	148.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,1ZHX7@1386|Bacillus	91061|Bacilli	G	phosphocarrier protein HPr	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HKD3_k127_8993348_0	1396.DJ87_807	0.0	1095.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC48@1386|Bacillus	91061|Bacilli	G	phosphotransferase system	ptsG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HKD3_k127_8993348_4	1169144.KB910924_gene606	3.911e-127	411.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,4HBB3@91061|Bacilli,1ZBDU@1386|Bacillus	91061|Bacilli	K	antiterminator	glcT	-	-	ko:K03480,ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
HKD3_k127_8993348_6	574375.BAGA_01755	3.006e-102	339.0	COG0561@1|root,COG0561@2|Bacteria,1V4WC@1239|Firmicutes,4HH83@91061|Bacilli,1ZEEH@1386|Bacillus	91061|Bacilli	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HKD3_k127_8993348_3	260799.BAS3965	3.462e-146	473.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,1ZCM7@1386|Bacillus	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD3_k127_8993348_10	1169144.KB910924_gene611	4.931e-77	263.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,1ZFNU@1386|Bacillus	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD3_k127_8993348_8	260799.BAS3968	1.793e-99	331.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,1ZDD6@1386|Bacillus	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD3_k127_8993348_12	224308.BSU23230	8.401e-48	177.0	COG1547@1|root,COG1547@2|Bacteria,1V7AS@1239|Firmicutes,4HI8I@91061|Bacilli,1ZR7S@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
HKD3_k127_8993348_11	1169144.KB910924_gene615	3.781e-49	178.0	COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,1ZHDK@1386|Bacillus	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ribT	-	-	ko:K02859	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD3_k127_8993348_9	545693.BMQ_4381	2.024e-82	274.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4HHA1@91061|Bacilli,1ZFRG@1386|Bacillus	91061|Bacilli	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HKD3_k127_8993348_5	1169144.KB910924_gene617	1.081e-125	408.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,1ZD5H@1386|Bacillus	91061|Bacilli	S	Secreted protein	ypuA	-	-	-	-	-	-	-	-	-	-	-	DUF1002
HKD3_k127_8993348_2	315749.Bcer98_2763	5.607e-249	775.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus	91061|Bacilli	EG	Stage V sporulation protein AF	spoVAF	-	-	ko:K06408	-	-	-	-	ko00000	-	-	-	GerA
HKD3_k127_8993348_15	574376.BAMA_09695	2.895e-15	76.0	29419@1|root,2ZRG2@2|Bacteria,1V3UB@1239|Firmicutes,4HI22@91061|Bacilli,1ZC8M@1386|Bacillus	91061|Bacilli	S	Stage V sporulation protein AE	spoVAEA	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAE
HKD3_k127_9074632_1	1396.DJ87_3599	2.113e-118	384.0	COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,1ZCZE@1386|Bacillus	91061|Bacilli	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HKD3_k127_9074632_0	315749.Bcer98_0839	5.409e-132	423.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,1ZBIZ@1386|Bacillus	91061|Bacilli	H	Lipoate-protein ligase	lplJ	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
HKD3_k127_9118066_0	666686.B1NLA3E_02750	1.695e-246	767.0	COG1366@1|root,COG3852@1|root,COG1366@2|Bacteria,COG3852@2|Bacteria,1TT64@1239|Firmicutes,4HCAK@91061|Bacilli,1ZDJS@1386|Bacillus	91061|Bacilli	T	STAS domain	rsbRD	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	HATPase_c,HisKA,STAS
HKD3_k127_9118066_3	1405.DJ92_4707	2.697e-76	258.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,1ZGBN@1386|Bacillus	91061|Bacilli	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD3_k127_9118066_2	315730.BcerKBAB4_1963	1.113e-125	409.0	COG0491@1|root,COG0491@2|Bacteria,1U9UR@1239|Firmicutes,4HCI8@91061|Bacilli,1ZAQ9@1386|Bacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	fprA1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD3_k127_9118066_1	574376.BAMA_20035	1.886e-150	484.0	COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,1ZC9I@1386|Bacillus	91061|Bacilli	L	COG0513 Superfamily II DNA and RNA helicases	yfmL	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HKD3_k127_9118066_4	1267580.AF6_1586	2.503e-40	150.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,21V1V@150247|Anoxybacillus	91061|Bacilli	F	Formate--tetrahydrofolate ligase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HKD3_k127_9122658_2	1297581.H919_12868	2.053e-182	579.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TSQZ@1239|Firmicutes,4HCYZ@91061|Bacilli	91061|Bacilli	P	Zn-dependent	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
HKD3_k127_9122658_4	1175306.GWL_05600	2.797e-94	314.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HKD3_k127_9122658_7	158190.SpiGrapes_0213	2.464e-52	192.0	COG0765@1|root,COG0765@2|Bacteria,2J5BG@203691|Spirochaetes	2|Bacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HKD3_k127_9122658_6	158190.SpiGrapes_0212	2.709e-55	205.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030,ko:K02424	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
HKD3_k127_9122658_8	1461580.CCAS010000061_gene3878	9.124e-35	134.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus	91061|Bacilli	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD3_k127_9122658_5	997296.PB1_03805	2.087e-62	224.0	2DWNN@1|root,3417F@2|Bacteria,1W28F@1239|Firmicutes,4I1N7@91061|Bacilli,1ZHY2@1386|Bacillus	91061|Bacilli	-	-	-	-	1.14.13.238	ko:K22344	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD3_k127_9122658_3	1307436.PBF_12522	9.54e-110	356.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,4HA34@91061|Bacilli,1ZQQY@1386|Bacillus	91061|Bacilli	P	Spore Coat	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
HKD3_k127_9122658_9	997296.PB1_17354	5.92e-34	132.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,4HKID@91061|Bacilli,1ZI8X@1386|Bacillus	91061|Bacilli	S	CotJB protein	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
HKD3_k127_9122658_10	574375.BAGA_28235	3.389e-32	126.0	2E85N@1|root,332J6@2|Bacteria,1VFSE@1239|Firmicutes,4HNIY@91061|Bacilli,1ZISW@1386|Bacillus	91061|Bacilli	S	Spore coat associated protein JA (CotJA)	cotJA	-	-	ko:K06332	-	-	-	-	ko00000	-	-	-	CotJA
HKD3_k127_9122658_11	1461580.CCAS010000021_gene2294	1.512e-30	126.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HKD3_k127_9122658_1	1122918.KB907246_gene1245	2.482e-246	772.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,26QMC@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_9122658_0	1243664.CAVL020000005_gene391	3.481e-267	834.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus	91061|Bacilli	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD3_k127_9165117_1	315730.BcerKBAB4_4109	5.303e-37	142.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,1ZBGC@1386|Bacillus	91061|Bacilli	E	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine	yitJ	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
HKD3_k127_9165117_0	574375.BAGA_02820	0.0	1847.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus	91061|Bacilli	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HKD3_k127_9165117_2	1449063.JMLS01000008_gene5061	5.85e-05	47.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,26QGD@186822|Paenibacillaceae	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD3_k127_9187529_2	1200792.AKYF01000010_gene2219	6.407e-85	284.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,26RB7@186822|Paenibacillaceae	91061|Bacilli	C	Monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD3_k127_9187529_1	1121091.AUMP01000001_gene543	4.127e-140	451.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli	91061|Bacilli	S	Transporter	yocS	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	iYO844.BSU19350	SBF
HKD3_k127_9187529_3	1122915.AUGY01000134_gene2120	8.131e-37	144.0	COG0394@1|root,COG0394@2|Bacteria,1TTE8@1239|Firmicutes,4IPG0@91061|Bacilli,270AS@186822|Paenibacillaceae	91061|Bacilli	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
HKD3_k127_9187529_0	315730.BcerKBAB4_1786	1.586e-150	492.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,1V0AI@1239|Firmicutes,4HDZZ@91061|Bacilli,1ZEHB@1386|Bacillus	91061|Bacilli	P	protein, homolog of Cu resistance protein CopC	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,YtkA
HKD3_k127_9195121_2	666686.B1NLA3E_02955	3.705e-155	493.0	COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.28	ko:K20938	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
HKD3_k127_9195121_8	574375.BAGA_16485	2.59e-07	55.0	29QVP@1|root,30BVV@2|Bacteria,1U8R6@1239|Firmicutes,4IIP5@91061|Bacilli,1ZNVV@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9195121_3	1169144.KB910925_gene132	1.182e-130	425.0	28MSG@1|root,2ZB0U@2|Bacteria,1TT1H@1239|Firmicutes,4HBNQ@91061|Bacilli,1ZCHW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2515)	yppC	-	-	-	-	-	-	-	-	-	-	-	DUF2515
HKD3_k127_9195121_5	1396.DJ87_5412	1.119e-93	314.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,1ZCV9@1386|Bacillus	91061|Bacilli	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
HKD3_k127_9195121_0	1169144.KB910925_gene134	2.638e-294	925.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	pbp1A	GO:0005575,GO:0005576	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD3_k127_9195121_1	439292.Bsel_0552	2.465e-195	616.0	COG0533@1|root,COG1403@1|root,COG0533@2|Bacteria,COG1403@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,26NFQ@186821|Sporolactobacillaceae	91061|Bacilli	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD3_k127_9195121_7	1169144.KB910925_gene135	8.521e-35	139.0	2EGVD@1|root,33AMM@2|Bacteria,1VKVK@1239|Firmicutes,4HRYS@91061|Bacilli,1ZITC@1386|Bacillus	91061|Bacilli	-	-	ypoC	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9195121_4	345219.Bcoa_2993	4.276e-119	385.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,1ZBJE@1386|Bacillus	91061|Bacilli	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD3_k127_9195121_6	574375.BAGA_16520	3.788e-40	149.0	COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,1ZC34@1386|Bacillus	91061|Bacilli	L	DNA replication protein DnaD	dnaD	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2,HTH_36
HKD3_k127_9244473_1	545693.BMQ_0362	8.423e-163	520.0	COG4362@1|root,COG4362@2|Bacteria,1TRDM@1239|Firmicutes,4HAR0@91061|Bacilli,1ZB33@1386|Bacillus	91061|Bacilli	C	Belongs to the NOS family. Bacterial NOS oxygenase subfamily	nos	GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004517,GO:0006807,GO:0006809,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017144,GO:0034641,GO:0042133,GO:0042136,GO:0044237,GO:0044249,GO:0044271,GO:0046209,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:1903409,GO:2001057	1.14.14.47	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	-	R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000	-	-	-	NO_synthase
HKD3_k127_9244473_6	272558.10174381	3.398e-119	391.0	COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,1ZAU6@1386|Bacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HKD3_k127_9244473_0	1157490.EL26_20450	0.0	1178.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,278UT@186823|Alicyclobacillaceae	91061|Bacilli	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD3_k127_9244473_9	1347369.CCAD010000022_gene1684	2.604e-25	114.0	COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,1ZDP2@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ycfA	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD3_k127_9244473_8	666686.B1NLA3E_13885	1.036e-33	138.0	COG0398@1|root,COG0398@2|Bacteria,1UBKZ@1239|Firmicutes,4IN17@91061|Bacilli,1ZMHQ@1386|Bacillus	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD3_k127_9244473_7	1231057.AMGD01000025_gene2954	5.627e-55	199.0	COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,4HHXX@91061|Bacilli,26FZT@186818|Planococcaceae	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD3_k127_9244473_3	315730.BcerKBAB4_3370	1.059e-133	430.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,4HBI5@91061|Bacilli,1ZCGM@1386|Bacillus	91061|Bacilli	P	ABC transporter	ptxC	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
HKD3_k127_9244473_5	315749.Bcer98_2338	8.397e-121	392.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,1ZB5I@1386|Bacillus	91061|Bacilli	P	ABC transporter	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
HKD3_k127_9244473_2	1501230.ET33_14975	1.665e-135	434.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,26S0C@186822|Paenibacillaceae	91061|Bacilli	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
HKD3_k127_9244473_4	574375.BAGA_10360	3.358e-122	394.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,1ZE0C@1386|Bacillus	91061|Bacilli	P	Phosphonate ABC transporter	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
HKD3_k127_9313215_4	1405.DJ92_4672	1.662e-67	233.0	COG0454@1|root,COG0456@2|Bacteria,1V99J@1239|Firmicutes,4HQK9@91061|Bacilli	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD3_k127_9313215_5	1397699.JNIS01000001_gene1041	2.289e-58	207.0	COG4974@1|root,COG4974@2|Bacteria,1UCSJ@1239|Firmicutes,4HIEB@91061|Bacilli	91061|Bacilli	L	PFAM Plasmid pRiA4b	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
HKD3_k127_9313215_2	315749.Bcer98_0410	1.203e-120	392.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,4HAQI@91061|Bacilli,1ZBYP@1386|Bacillus	91061|Bacilli	G	deacetylase	pdaA	GO:0005575,GO:0016020	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HKD3_k127_9313215_6	326423.RBAM_033800	1.742e-43	162.0	COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli,1ZHA4@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ywnA	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD3_k127_9313215_3	1131730.BAVI_12704	3.63e-107	350.0	COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HAJ4@91061|Bacilli,1ZESA@1386|Bacillus	91061|Bacilli	S	NAD(P)H-binding	ywnB	-	-	ko:K07118	-	-	-	-	ko00000	-	-	-	NAD_binding_10
HKD3_k127_9313215_0	574375.BAGA_20110	7.449e-284	876.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TSJ8@1239|Firmicutes,4IQV9@91061|Bacilli,1ZRNT@1386|Bacillus	91061|Bacilli	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
HKD3_k127_9313215_7	574375.BAGA_26675	1.558e-23	104.0	2CEJ8@1|root,33H3W@2|Bacteria,1VMMF@1239|Firmicutes,4HRK8@91061|Bacilli,1ZIWC@1386|Bacillus	91061|Bacilli	-	-	yfjT	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9313215_1	1405.DJ92_3061	4.288e-132	423.0	COG0535@1|root,COG0535@2|Bacteria,1TRC8@1239|Firmicutes,4HA9Q@91061|Bacilli,1ZAVK@1386|Bacillus	91061|Bacilli	S	YfkB-like domain	yfkA	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,YfkB
HKD3_k127_9601935_2	1396.DJ87_301	3.854e-71	249.0	2AZZM@1|root,31S9P@2|Bacteria,1V6WH@1239|Firmicutes,4HMZM@91061|Bacilli,1ZDWA@1386|Bacillus	91061|Bacilli	S	YtxC-like family	ytxC	-	-	-	-	-	-	-	-	-	-	-	YtxC
HKD3_k127_9601935_1	471223.GWCH70_2663	1.158e-124	406.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,1WF51@129337|Geobacillus	91061|Bacilli	L	Primosomal protein DnaI N-terminus	dnaI	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	DnaI_N,IstB_IS21
HKD3_k127_9601935_0	1396.DJ87_299	1.899e-163	527.0	COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,1ZBJY@1386|Bacillus	91061|Bacilli	L	Membrane attachment protein	dnaB	-	-	ko:K03346	-	-	-	-	ko00000,ko03032	-	-	-	DnaB_2
HKD3_k127_9657565_48	1121091.AUMP01000032_gene3076	2.043e-08	58.0	2ECZC@1|root,339V3@2|Bacteria,1VMJZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_46	1121091.AUMP01000032_gene3080	2.433e-09	64.0	2EH6G@1|root,33AYC@2|Bacteria,1VMIH@1239|Firmicutes,4HRRB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_30	1295642.H839_16063	7.168e-28	119.0	COG4508@1|root,COG4508@2|Bacteria,1VAGF@1239|Firmicutes,4HKQ3@91061|Bacilli,1WGTJ@129337|Geobacillus	91061|Bacilli	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
HKD3_k127_9657565_40	218284.CCDN010000001_gene823	4.534e-15	79.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HYG4@91061|Bacilli	91061|Bacilli	K	SpoVT / AbrB like domain	-	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
HKD3_k127_9657565_24	1307436.PBF_04280	5.812e-40	153.0	2DGIG@1|root,2ZW42@2|Bacteria,1W2CA@1239|Firmicutes,4I1J0@91061|Bacilli,1ZJES@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_5	1307436.PBF_21953	6.111e-170	538.0	COG0175@1|root,COG0175@2|Bacteria,1TQBQ@1239|Firmicutes,4HD3W@91061|Bacilli,1ZFD1@1386|Bacillus	91061|Bacilli	EH	sulfate reduction	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
HKD3_k127_9657565_49	1462526.BN990_03860	3.026e-08	59.0	2EPCB@1|root,33GZ2@2|Bacteria,1VNAU@1239|Firmicutes,4HSS9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_39	642492.Clole_0961	2.26e-15	78.0	29774@1|root,2ZUF0@2|Bacteria,1W4Q0@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_41	574376.BAMA_12500	7.055e-14	76.0	2A6N0@1|root,30VFU@2|Bacteria,1U8N8@1239|Firmicutes,4IIK4@91061|Bacilli,1ZNQC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_50	756499.Desde_1069	3.625e-08	54.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_23	491915.Aflv_0658	4.123e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,1VAEY@1239|Firmicutes,4HMVP@91061|Bacilli,21W7W@150247|Anoxybacillus	91061|Bacilli	K	Sigma-70, region 4	xpf	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
HKD3_k127_9657565_20	1178540.BA70_18515	4.046e-51	187.0	COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4HFES@91061|Bacilli,1ZS0D@1386|Bacillus	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD3_k127_9657565_22	349161.Dred_1202	2.792e-40	158.0	COG4220@1|root,COG4220@2|Bacteria,1VGX7@1239|Firmicutes,24S8B@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_1	1449063.JMLS01000030_gene447	1.179e-247	777.0	COG5525@1|root,COG5525@2|Bacteria,1TQBY@1239|Firmicutes,4HD7Q@91061|Bacilli,26VH9@186822|Paenibacillaceae	91061|Bacilli	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
HKD3_k127_9657565_36	1449063.JMLS01000030_gene448	2.508e-22	97.0	2EJEU@1|root,30W2N@2|Bacteria,1U5WY@1239|Firmicutes,4I8X4@91061|Bacilli,270NG@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_2	1460634.JCM19037_4599	3.294e-234	734.0	COG5511@1|root,COG5511@2|Bacteria,1TQ8B@1239|Firmicutes,4HCQE@91061|Bacilli	91061|Bacilli	S	Portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal_2
HKD3_k127_9657565_10	1285586.H131_21892	1.826e-91	312.0	COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,3IYGP@400634|Lysinibacillus	91061|Bacilli	OU	Belongs to the peptidase S14 family	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD3_k127_9657565_29	1157490.EL26_01770	1.548e-29	121.0	2E4UU@1|root,32ZP7@2|Bacteria,1VEZP@1239|Firmicutes,4HQGN@91061|Bacilli	91061|Bacilli	S	Bacteriophage lambda head decoration protein D	-	-	-	-	-	-	-	-	-	-	-	-	HDPD
HKD3_k127_9657565_6	1444309.JAQG01000145_gene2693	5.304e-149	478.0	2C57E@1|root,2Z8WK@2|Bacteria,1TPTU@1239|Firmicutes,4HBUR@91061|Bacilli,26X7K@186822|Paenibacillaceae	91061|Bacilli	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
HKD3_k127_9657565_43	665959.HMPREF1013_00840	1.088e-13	74.0	2E24F@1|root,32XBM@2|Bacteria,1VE9G@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Gifsy-2
HKD3_k127_9657565_13	665959.HMPREF1013_00839	1.694e-71	246.0	2DMPX@1|root,32SY7@2|Bacteria,1VBPX@1239|Firmicutes,4HPDW@91061|Bacilli	91061|Bacilli	S	Prophage minor tail protein Z (GPZ)	-	-	-	-	-	-	-	-	-	-	-	-	Minor_tail_Z
HKD3_k127_9657565_25	665959.HMPREF1013_00838	1.112e-39	152.0	2ECAW@1|root,33698@2|Bacteria,1VH4W@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_53	857293.CAAU_0805	1.381e-06	54.0	2EGGU@1|root,33A8W@2|Bacteria,1VQ77@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_3	665959.HMPREF1013_00836	9.081e-190	603.0	COG3497@1|root,COG3497@2|Bacteria,1TPG4@1239|Firmicutes,4HCYP@91061|Bacilli	91061|Bacilli	S	Phage tail	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	-
HKD3_k127_9657565_15	665959.HMPREF1013_00835	4.655e-65	226.0	COG3498@1|root,COG3498@2|Bacteria,1VDBM@1239|Firmicutes,4HKGB@91061|Bacilli	91061|Bacilli	S	Tail protein	-	-	-	ko:K06908	-	-	-	-	ko00000	-	-	-	Phage_tube
HKD3_k127_9657565_34	665959.HMPREF1013_00834	1.22e-22	100.0	2E89Y@1|root,332NT@2|Bacteria,1VF7K@1239|Firmicutes	1239|Firmicutes	S	Phage tail assembly chaperone proteins, E, or 41 or 14	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_7
HKD3_k127_9657565_0	665959.HMPREF1013_00833	0.0	1287.0	COG3953@1|root,COG5280@1|root,COG5412@1|root,COG3953@2|Bacteria,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,1ZS5N@1386|Bacillus	91061|Bacilli	D	Phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
HKD3_k127_9657565_37	665959.HMPREF1013_00832	1.925e-21	96.0	COG5004@1|root,COG5004@2|Bacteria,1VKIE@1239|Firmicutes,4HRFJ@91061|Bacilli	91061|Bacilli	S	Phage Tail Protein X	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_X
HKD3_k127_9657565_7	1423321.AS29_22325	1.188e-135	439.0	COG3500@1|root,COG3500@2|Bacteria,1UZ7W@1239|Firmicutes,4HG3N@91061|Bacilli,1ZMEU@1386|Bacillus	91061|Bacilli	S	Phage late control gene D protein (GPD)	-	-	-	ko:K06905	-	-	-	-	ko00000	-	-	-	Phage_GPD
HKD3_k127_9657565_19	349161.Dred_1217	1.701e-51	186.0	COG4540@1|root,COG4540@2|Bacteria,1VE16@1239|Firmicutes	1239|Firmicutes	S	Baseplate assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_base_V
HKD3_k127_9657565_11	665959.HMPREF1013_00829	6.361e-82	277.0	COG3103@1|root,COG4991@2|Bacteria,1UMPH@1239|Firmicutes,4ITXZ@91061|Bacilli	91061|Bacilli	T	Phage P2 GpU	-	-	-	-	-	-	-	-	-	-	-	-	Phage_P2_GpU,SH3_3
HKD3_k127_9657565_9	665959.HMPREF1013_00827	3.362e-118	390.0	COG3948@1|root,COG3948@2|Bacteria,1U044@1239|Firmicutes,4HCD5@91061|Bacilli	91061|Bacilli	S	Baseplate J protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
HKD3_k127_9657565_31	665959.HMPREF1013_00826	8.879e-28	123.0	COG4385@1|root,COG4385@2|Bacteria,1V74W@1239|Firmicutes,4HJ6B@91061|Bacilli	91061|Bacilli	S	Tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
HKD3_k127_9657565_38	485916.Dtox_4253	2.118e-20	93.0	297AR@1|root,2ZUID@2|Bacteria,1W2SN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_17	1230341.MJ3_13709	5.806e-55	197.0	2E8G9@1|root,332UJ@2|Bacteria,1UKR2@1239|Firmicutes,4HXWP@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_26	1122925.KB895376_gene449	1.957e-37	145.0	2CFSR@1|root,335Q8@2|Bacteria,1VEPJ@1239|Firmicutes,4HZ5A@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_8	1230341.MJ3_13719	3.902e-135	437.0	COG1262@1|root,COG1262@2|Bacteria,1UY2C@1239|Firmicutes,4HTTS@91061|Bacilli	91061|Bacilli	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD3_k127_9657565_18	1218173.BALCAV_0213775	4.043e-54	191.0	2DMHJ@1|root,32RM0@2|Bacteria,1VBZA@1239|Firmicutes	1239|Firmicutes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD3_k127_9657565_4	1218173.BALCAV_0213780	1.021e-171	544.0	COG3344@1|root,COG3344@2|Bacteria,1UZGP@1239|Firmicutes,4HHRF@91061|Bacilli	91061|Bacilli	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
HKD3_k127_9657565_33	1347368.HG964404_gene4963	3.44e-23	102.0	2DJSC@1|root,3075B@2|Bacteria,1U11V@1239|Firmicutes,4IAI5@91061|Bacilli,1ZKEQ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_35	1444310.JANV01000162_gene1157	1.359e-22	98.0	2ERH2@1|root,33J2J@2|Bacteria,1VP49@1239|Firmicutes,4HSDF@91061|Bacilli,1ZJEW@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
HKD3_k127_9657565_16	1243664.CAVL020000019_gene3741	2.234e-56	203.0	COG0860@1|root,COG0860@2|Bacteria,1V8U7@1239|Firmicutes,4IQE9@91061|Bacilli,1ZKHI@1386|Bacillus	91061|Bacilli	M	Ami_3	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
HKD3_k127_9657565_32	1158601.I585_04160	1.904e-27	119.0	2DPCP@1|root,331IF@2|Bacteria,1VHK6@1239|Firmicutes,4HNK3@91061|Bacilli,4B2VG@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_27	574376.BAMA_15625	1.673e-34	138.0	COG0789@1|root,COG0789@2|Bacteria,1UAZ6@1239|Firmicutes,4IMC4@91061|Bacilli,1ZJSE@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_42	1285586.H131_04864	8.637e-14	76.0	29R5I@1|root,30C6U@2|Bacteria,1U9AZ@1239|Firmicutes,4IJDU@91061|Bacilli,3IZRR@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_12	1385510.N781_00620	2.173e-75	266.0	2DBI8@1|root,2Z9F3@2|Bacteria,1UIM3@1239|Firmicutes,4ISN1@91061|Bacilli	91061|Bacilli	-	-	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
HKD3_k127_9657565_14	1408303.JNJJ01000063_gene4843	2.468e-65	235.0	COG0582@1|root,COG0582@2|Bacteria,1V3XQ@1239|Firmicutes,4HI9U@91061|Bacilli,1ZF16@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
HKD3_k127_9657565_21	1396.DJ87_5281	9.72e-48	187.0	2EWFZ@1|root,33PUD@2|Bacteria,1VR7B@1239|Firmicutes,4HU9H@91061|Bacilli,1ZIF9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_45	985665.HPL003_07420	8.987e-10	62.0	29QZV@1|root,30799@2|Bacteria,1U19K@1239|Firmicutes,4IARQ@91061|Bacilli,2732T@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_9657565_44	272558.10174060	2.456e-12	72.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli,1ZJSB@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HKD3_k127_9657565_54	1123309.AQYB01000029_gene966	5.548e-06	51.0	COG1476@1|root,COG1476@2|Bacteria,1V624@1239|Firmicutes,4HPEU@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD3_k127_96811_2	1405.DJ92_2668	1.734e-29	118.0	COG1396@1|root,COG1396@2|Bacteria,1VIT6@1239|Firmicutes,4HP4J@91061|Bacilli,1ZJ4Q@1386|Bacillus	91061|Bacilli	K	transcriptional	yazB	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD3_k127_96811_1	1169144.KB910956_gene4096	3.343e-185	582.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,1ZC6T@1386|Bacillus	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
HKD3_k127_96811_0	1396.DJ87_5554	2.274e-287	887.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,1ZAVI@1386|Bacillus	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD3_k127_97277_11	1169144.KB910924_gene488	2.014e-48	179.0	2DMFC@1|root,32R4R@2|Bacteria,1VC90@1239|Firmicutes,4HK48@91061|Bacilli,1ZQRB@1386|Bacillus	91061|Bacilli	S	Transcription factor RsfA	-	-	-	-	-	-	-	-	-	-	-	-	Myb_DNA-bind_6
HKD3_k127_97277_5	491915.Aflv_1843	1.546e-82	283.0	COG1024@1|root,COG1024@2|Bacteria,1UZHP@1239|Firmicutes,4HEEK@91061|Bacilli,21WQ2@150247|Anoxybacillus	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HKD3_k127_97277_16	260799.BAS3774	1.375e-31	123.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,1ZJ4F@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HKD3_k127_97277_8	1169144.KB910924_gene490	9.735e-60	211.0	COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,1ZGJH@1386|Bacillus	91061|Bacilli	S	metal-binding, possibly nucleic acid-binding protein	ylbN	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HKD3_k127_97277_2	935837.JAEK01000014_gene5109	7.074e-126	415.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,1ZC63@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0348 family	ylbM	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
HKD3_k127_97277_3	1169144.KB910924_gene492	4.66e-121	397.0	COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,1ZAW6@1386|Bacillus	91061|Bacilli	T	Belongs to the peptidase S16 family	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
HKD3_k127_97277_1	1169144.KB910924_gene493	7.533e-131	421.0	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,1ZBCG@1386|Bacillus	91061|Bacilli	S	esterase of the alpha-beta hydrolase superfamily	ylbK	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HKD3_k127_97277_0	198094.BA_4138	3.426e-144	467.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus	91061|Bacilli	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
HKD3_k127_97277_7	1499680.CCFE01000024_gene2865	5.691e-71	243.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,1ZFNZ@1386|Bacillus	91061|Bacilli	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD3_k127_97277_4	1169144.KB910924_gene496	1.845e-86	289.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,1ZFNI@1386|Bacillus	91061|Bacilli	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD3_k127_97277_9	574376.BAMA_09025	4.432e-56	198.0	2CC47@1|root,2ZQ3T@2|Bacteria,1V53R@1239|Firmicutes,4HMS7@91061|Bacilli,1ZR7Z@1386|Bacillus	91061|Bacilli	S	methylthioribose kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD3_k127_97277_13	315749.Bcer98_2635	2.058e-40	151.0	COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,1ZI4I@1386|Bacillus	91061|Bacilli	S	UPF0298 protein	ylbG	-	-	-	-	-	-	-	-	-	-	-	DUF2129
HKD3_k127_97277_10	315749.Bcer98_2636	8.728e-54	192.0	COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli,1ZG76@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0342 family	ylbF	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HKD3_k127_97277_6	315749.Bcer98_2637	5.936e-77	262.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,1ZDQW@1386|Bacillus	91061|Bacilli	G	Belongs to the phosphoglycerate mutase family	yhfR	-	5.4.2.12	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HKD3_k127_97277_17	574375.BAGA_01105	1.721e-29	121.0	2ED1C@1|root,336YB@2|Bacteria,1VJ46@1239|Firmicutes,4HPWX@91061|Bacilli,1ZJ6S@1386|Bacillus	91061|Bacilli	S	YlbE-like protein	ylbE	-	-	-	-	-	-	-	-	-	-	-	YlbE
HKD3_k127_97277_12	574376.BAMA_09050	1.72e-44	166.0	2DV4S@1|root,32UYM@2|Bacteria,1VA7R@1239|Firmicutes,4HMUX@91061|Bacilli,1ZI1G@1386|Bacillus	91061|Bacilli	S	Putative coat protein	ylbD	-	-	-	-	-	-	-	-	-	-	-	YlbD_coat
HKD3_k127_97277_18	574375.BAGA_01115	1.146e-14	74.0	COG2340@1|root,COG2340@2|Bacteria,1UYZ4@1239|Firmicutes,4HBTC@91061|Bacilli,1ZCGK@1386|Bacillus	91061|Bacilli	S	protein with SCP PR1 domains	ylbC	-	-	-	-	-	-	-	-	-	-	-	CAP,CAP_assoc_N
HKD3_k127_97277_14	315730.BcerKBAB4_3765	4.065e-37	143.0	2DN53@1|root,32VJF@2|Bacteria,1VBUZ@1239|Firmicutes,4HMZY@91061|Bacilli,1ZS3B@1386|Bacillus	91061|Bacilli	S	YugN-like family	ylbA	-	-	-	-	-	-	-	-	-	-	-	YugN
HKD3_k127_97277_15	574375.BAGA_01130	1.022e-34	134.0	COG3336@1|root,COG3336@2|Bacteria,1TQFK@1239|Firmicutes,4H9WN@91061|Bacilli,1ZBC8@1386|Bacillus	91061|Bacilli	S	cytochrome c oxidase	ctaG	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
## 2823 queries scanned
## Total time (seconds): 46.621235847473145
## Rate: 60.55 q/s