## Fri Nov 15 09:04:33 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin10/HSJS_1_bin.34.fa -m mmseqs --itype genome -o HSJS_1_bin.34 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HSJS_1_bin.34 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs HSJS1_k127_1009890_1 283942.IL2043 4.412e-44 168.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,2QFS9@267893|Idiomarinaceae 1236|Gammaproteobacteria G Inositol monophosphatase suhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2538,iPC815.YPO2899 Inositol_P HSJS1_k127_1009890_0 429009.Adeg_0371 1.233e-116 385.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,42F1H@68295|Thermoanaerobacterales 186801|Clostridia F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 HSJS1_k127_102178_0 1278073.MYSTI_08098 5.913e-147 483.0 COG2204@1|root,COG2204@2|Bacteria,1RAVV@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Sigma54_activat HSJS1_k127_102178_1 518766.Rmar_2622 1.967e-73 258.0 COG0708@1|root,COG0708@2|Bacteria,4NH0B@976|Bacteroidetes 976|Bacteroidetes L exodeoxyribonuclease III xthA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos HSJS1_k127_102178_2 502025.Hoch_2041 5.258e-68 241.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria 68525|delta/epsilon subdivisions KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase HSJS1_k127_1024835_9 223926.28809968 7.551e-05 55.0 COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RS16@1236|Gammaproteobacteria,1XZJZ@135623|Vibrionales 135623|Vibrionales S Saccharopine dehydrogenase - - - - - - - - - - - - Sacchrp_dh_NADP HSJS1_k127_1024835_3 768066.HELO_2552 4.619e-75 265.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1XH9Y@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N HSJS1_k127_1024835_5 1316936.K678_05543 3.478e-38 150.0 COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,2JSR9@204441|Rhodospirillales 204441|Rhodospirillales S Stringent starvation protein B - - - ko:K09985 - - - - ko00000 - - - SspB HSJS1_k127_1024835_8 204669.Acid345_2334 1.186e-08 66.0 COG2948@1|root,COG2948@2|Bacteria,3Y81Q@57723|Acidobacteria,2JN9S@204432|Acidobacteriia 204432|Acidobacteriia U multi-organism process - - - ko:K03195 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - TrbI HSJS1_k127_1024835_6 266117.Rxyl_0191 8.164e-33 133.0 COG0633@1|root,COG0633@2|Bacteria 2|Bacteria C Ferredoxin fdx5 - - ko:K04755 - - - - ko00000 - - - Fer2 HSJS1_k127_1024835_4 1089550.ATTH01000001_gene2218 2.763e-52 196.0 COG0204@1|root,COG0204@2|Bacteria 2|Bacteria I Acyl-transferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase HSJS1_k127_1024835_7 561175.KB894102_gene1021 3.071e-23 108.0 COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria 201174|Actinobacteria S oxidoreductase - - - - - - - - - - - - DUF393 HSJS1_k127_1024835_0 1129374.AJE_07865 2.071e-109 377.0 COG2755@1|root,COG2755@2|Bacteria,1R43M@1224|Proteobacteria,1RRTK@1236|Gammaproteobacteria,465MH@72275|Alteromonadaceae 1236|Gammaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 HSJS1_k127_1024835_1 1195246.AGRI_10036 3.194e-108 379.0 COG2755@1|root,COG2755@2|Bacteria,1R43M@1224|Proteobacteria,1RRTK@1236|Gammaproteobacteria,465MH@72275|Alteromonadaceae 1236|Gammaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 HSJS1_k127_1024835_2 502025.Hoch_4298 3.535e-99 332.0 COG1999@1|root,COG2010@1|root,COG1999@2|Bacteria,COG2010@2|Bacteria,1R725@1224|Proteobacteria,430D9@68525|delta/epsilon subdivisions,2X5YK@28221|Deltaproteobacteria,2Z37S@29|Myxococcales 28221|Deltaproteobacteria C SCO1/SenC - - - - - - - - - - - - SCO1-SenC HSJS1_k127_1061115_1 381666.H16_B2417 2.232e-27 124.0 COG3455@1|root,COG3455@2|Bacteria,1N723@1224|Proteobacteria,2VWJC@28216|Betaproteobacteria,1K6TX@119060|Burkholderiaceae 28216|Betaproteobacteria S Type VI secretion system protein DotU - - - ko:K11892 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DotU HSJS1_k127_1061115_0 1192034.CAP_6440 1.149e-107 364.0 COG3522@1|root,COG3522@2|Bacteria,1RD5T@1224|Proteobacteria,43F3D@68525|delta/epsilon subdivisions,2X38C@28221|Deltaproteobacteria,2YUTK@29|Myxococcales 28221|Deltaproteobacteria S Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE - - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE HSJS1_k127_1061115_2 448385.sce9347 2.919e-17 89.0 2E53M@1|root,32ZWP@2|Bacteria,1N5H5@1224|Proteobacteria 1224|Proteobacteria - - - - - ko:K11918 - - - - ko00000,ko02044 - - - - HSJS1_k127_1071250_2 644282.Deba_0427 4.882e-08 66.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_1071250_1 886293.Sinac_1308 1.618e-61 237.0 COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes 203682|Planctomycetes S PFAM Peptidase M16 inactive domain - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_1071250_0 243090.RB11266 9.431e-69 247.0 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity cpdA - - - - - - - - - - - Metallophos,Metallophos_2 HSJS1_k127_1077097_1 926550.CLDAP_29040 3.601e-23 105.0 COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi 200795|Chloroflexi S NAD-dependent epimerase dehydratase - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase HSJS1_k127_1077097_0 204669.Acid345_1514 4.936e-176 569.0 COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia 204432|Acidobacteriia V ABC transporter, transmembrane - - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran HSJS1_k127_1077097_2 446470.Snas_0303 7.244e-23 104.0 COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4EYJ1@85014|Glycomycetales 201174|Actinobacteria J Putative methyltransferase trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 HSJS1_k127_1083878_1 1177179.A11A3_16045 3.166e-72 269.0 COG0300@1|root,COG0300@2|Bacteria,1R7MT@1224|Proteobacteria,1S0XC@1236|Gammaproteobacteria,1XR3K@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short HSJS1_k127_1083878_0 76114.ebA3623 5.005e-90 310.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2VHD1@28216|Betaproteobacteria,2KVBD@206389|Rhodocyclales 206389|Rhodocyclales C Alanine dehydrogenase/PNT, N-terminal domain - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N HSJS1_k127_1083878_3 1111069.TCCBUS3UF1_4090 8.262e-32 141.0 COG0427@1|root,COG0427@2|Bacteria,1WJIT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Acetyl-CoA hydrolase/transferase C-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro HSJS1_k127_1083878_2 1502851.FG93_05058 1.299e-36 153.0 COG0421@1|root,COG0421@2|Bacteria,1PD54@1224|Proteobacteria,2V9CT@28211|Alphaproteobacteria,3JYAK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Spermine/spermidine synthase domain - - - - - - - - - - - - Spermine_synth HSJS1_k127_1086139_2 391625.PPSIR1_35712 5.417e-35 138.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria 28221|Deltaproteobacteria G K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - Sortilin-Vps10 HSJS1_k127_1086139_4 225849.swp_0600 2.662e-16 86.0 2E4J8@1|root,32ZEA@2|Bacteria,1R37Q@1224|Proteobacteria,1STTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1086139_1 118168.MC7420_1265 1.488e-125 407.0 COG0300@1|root,COG0300@2|Bacteria,1GQM8@1117|Cyanobacteria,1HHZ1@1150|Oscillatoriales 1117|Cyanobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short HSJS1_k127_1086139_3 1356852.N008_20540 1.932e-25 113.0 2DTU1@1|root,33MMF@2|Bacteria,4NWD8@976|Bacteroidetes,47SX0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - HSJS1_k127_1086139_0 631362.Thi970DRAFT_03022 2.773e-127 427.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1SX52@1236|Gammaproteobacteria,1X227@135613|Chromatiales 135613|Chromatiales F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C HSJS1_k127_1086139_5 1348663.KCH_02450 9.795e-11 73.0 2EABA@1|root,334FH@2|Bacteria,2HY0R@201174|Actinobacteria,2M4BX@2063|Kitasatospora 201174|Actinobacteria - - - - - - - - - - - - - - TIG HSJS1_k127_1090285_0 869210.Marky_0500 7.641e-111 382.0 COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH HSJS1_k127_1092972_0 329726.AM1_3935 5.387e-158 520.0 COG1716@1|root,COG5001@1|root,COG1716@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria 1117|Cyanobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9,Response_reg HSJS1_k127_1092972_1 290397.Adeh_1776 1.467e-134 447.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales 28221|Deltaproteobacteria J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL HSJS1_k127_1113844_1 1210884.HG799462_gene8307 5.187e-110 371.0 COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes 203682|Planctomycetes P COG0798 Arsenite efflux pump ACR3 and related - - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF HSJS1_k127_1113844_3 1150626.PHAMO_400030 1.561e-19 96.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - ko:K03892,ko:K21903 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 HSJS1_k127_1113844_0 1183438.GKIL_4354 7.159e-195 637.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_1113844_2 1380390.JIAT01000014_gene6171 2.036e-71 244.0 COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria 84995|Rubrobacteria S Rubrerythrin - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin HSJS1_k127_112117_1 1266909.AUAG01000009_gene630 1.594e-24 108.0 COG5464@1|root,COG5464@2|Bacteria 2|Bacteria S double-stranded DNA endodeoxyribonuclease activity - - - - - - - - - - - - PDDEXK_2,Transposase_31 HSJS1_k127_112117_2 234267.Acid_4150 3.089e-21 94.0 COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria 57723|Acidobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 HSJS1_k127_112117_0 671143.DAMO_1933 1.5e-181 588.0 COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria 2|Bacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran HSJS1_k127_1121579_0 1163617.SCD_n02279 2.567e-118 415.0 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,Response_reg HSJS1_k127_1121579_2 35754.JNYJ01000070_gene4310 4.278e-84 293.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - ko:K08153 - M00717 - - ko00000,ko00002,ko02000 2.A.1.2.8 - - MFS_1,Sugar_tr HSJS1_k127_1121579_4 926550.CLDAP_09630 2.823e-17 90.0 arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - HSJS1_k127_1121579_1 269799.Gmet_0754 2.746e-99 337.0 COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,43UZT@69541|Desulfuromonadales 28221|Deltaproteobacteria S SPFH domain-Band 7 family - - - - - - - - - - - - Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2 HSJS1_k127_1121579_3 926569.ANT_25300 1.468e-47 180.0 COG2888@1|root,COG2888@2|Bacteria 2|Bacteria J peptidyl-tyrosine sulfation ybeL - 1.17.4.1,4.6.1.1 ko:K00525,ko:K01768 ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213 M00053,M00695 R00089,R00434,R02017,R02018,R02019,R02024 RC00295,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - DUF1451 HSJS1_k127_1121579_5 926569.ANT_25310 4.137e-12 74.0 COG1996@1|root,COG1996@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - DUF4379 HSJS1_k127_1122323_1 1131269.AQVV01000029_gene68 5.386e-68 239.0 COG0745@1|root,COG0745@2|Bacteria 1131269.AQVV01000029_gene68|- T phosphorelay signal transduction system - - - - - - - - - - - - - HSJS1_k127_1122323_0 880073.Calab_1764 3.759e-107 372.0 COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria 2|Bacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg HSJS1_k127_1122323_2 1122603.ATVI01000012_gene1134 3.685e-40 161.0 COG1404@1|root,COG2373@1|root,COG1404@2|Bacteria,COG2373@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X484@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the peptidase S8 family - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 HSJS1_k127_1123494_8 1419583.V466_22305 4.81e-15 90.0 COG4885@1|root,COG4885@2|Bacteria,1QZSY@1224|Proteobacteria 1224|Proteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554 HSJS1_k127_1123494_10 1035308.AQYY01000001_gene1534 7.514e-05 56.0 COG1749@1|root,COG2374@1|root,COG3525@1|root,COG1749@2|Bacteria,COG2374@2|Bacteria,COG3525@2|Bacteria 2|Bacteria G beta-N-acetylhexosaminidase activity flgK - 1.1.3.9 ko:K02388,ko:K02396,ko:K04618 ko00052,ko02040,map00052,map02040 - R01098 RC00194 ko00000,ko00001,ko01000,ko02035 - - - Big_5,DUF4082,Flg_bb_rod,Flg_bbr_C,LTD HSJS1_k127_1123494_7 671143.DAMO_1513 1.151e-28 134.0 COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria 2|Bacteria L Protein of unknown function (DUF3105) - - - - - - - - - - - - DDE_Tnp_ISAZ013,DUF3105,HTH_Tnp_IS630 HSJS1_k127_1123494_0 1283300.ATXB01000001_gene480 0.0 1059.0 COG0438@1|root,COG0438@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1XDS7@135618|Methylococcales 1224|Proteobacteria M Sucrose phosphate synthase, sucrose phosphatase-like mfpsA GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.246 ko:K13058 - - R08947 RC00005,RC00028 ko00000,ko01000 - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 HSJS1_k127_1123494_6 1192034.CAP_1140 6.373e-31 132.0 2A835@1|root,30X3P@2|Bacteria,1QB0X@1224|Proteobacteria,435DE@68525|delta/epsilon subdivisions,2WZR0@28221|Deltaproteobacteria,2Z2JH@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1123494_5 1121920.AUAU01000006_gene330 6.616e-69 259.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria 57723|Acidobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase HSJS1_k127_1123494_3 1123269.NX02_27645 7.284e-115 395.0 COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria,2TW44@28211|Alphaproteobacteria,2K7FJ@204457|Sphingomonadales 204457|Sphingomonadales IT Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 HSJS1_k127_1123494_4 518766.Rmar_1064 2.698e-97 350.0 COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes 976|Bacteroidetes P H( )-stimulated, divalent metal cation uptake system mntH - - - - - - - - - - - Nramp HSJS1_k127_1123494_1 1123277.KB893209_gene5800 2.691e-162 548.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,4NFBV@976|Bacteroidetes,47K85@768503|Cytophagia 976|Bacteroidetes EQ Hydantoinase/oxoprolinase - - 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B HSJS1_k127_1123494_2 1121904.ARBP01000004_gene917 1.583e-125 418.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,4NFBV@976|Bacteroidetes,47K85@768503|Cytophagia 976|Bacteroidetes EQ Hydantoinase/oxoprolinase - - 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B HSJS1_k127_1125487_3 1192034.CAP_1193 1.336e-75 271.0 COG1714@1|root,COG1714@2|Bacteria,1RAZN@1224|Proteobacteria,439VR@68525|delta/epsilon subdivisions,2X59U@28221|Deltaproteobacteria,2Z0B3@29|Myxococcales 28221|Deltaproteobacteria S RDD family - - - - - - - - - - - - RDD HSJS1_k127_1125487_2 1192034.CAP_1192 1.302e-100 346.0 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2YVHM@29|Myxococcales 28221|Deltaproteobacteria S Stage II sporulation protein M - - - - - - - - - - - - SpoIIM HSJS1_k127_1125487_1 502025.Hoch_3127 1.949e-113 381.0 COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,437ZW@68525|delta/epsilon subdivisions,2X39T@28221|Deltaproteobacteria,2YXDU@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 HSJS1_k127_1125487_0 1192034.CAP_4289 3.273e-124 413.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42YV7@68525|delta/epsilon subdivisions,2WTKH@28221|Deltaproteobacteria,2YYAX@29|Myxococcales 28221|Deltaproteobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 HSJS1_k127_1125487_7 46429.BV95_04102 1.071e-05 56.0 2C58E@1|root,32V5I@2|Bacteria,1N13T@1224|Proteobacteria,2UBSB@28211|Alphaproteobacteria,2K675@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF4129 HSJS1_k127_1125487_8 882086.SacxiDRAFT_1295 4.357e-05 54.0 COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,4E186@85010|Pseudonocardiales 201174|Actinobacteria A pathogenesis - - - - - - - - - - - - GPDPase_memb HSJS1_k127_1125487_6 452637.Oter_0314 1.604e-27 130.0 COG5373@1|root,COG5373@2|Bacteria,46UM1@74201|Verrucomicrobia 74201|Verrucomicrobia S Protein of unknown function (DUF3999) - - - - - - - - - - - - DUF3999 HSJS1_k127_1125487_4 497964.CfE428DRAFT_1104 1.996e-74 280.0 COG5373@1|root,COG5373@2|Bacteria,46S9T@74201|Verrucomicrobia 74201|Verrucomicrobia S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 HSJS1_k127_1127106_0 671143.DAMO_1445 1.436e-194 629.0 COG0417@1|root,COG1205@1|root,COG0417@2|Bacteria,COG1205@2|Bacteria,2NNKJ@2323|unclassified Bacteria 2|Bacteria L Domain of unknown function (DUF1998) yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 ko:K02336,ko:K06877 - - - - ko00000,ko01000,ko03400 - - - DEAD,DNA_pol_B,DNA_pol_B_exo1,DUF1998,Helicase_C HSJS1_k127_1127106_1 518766.Rmar_0728 8.379e-36 141.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1FJ6B@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Glycine zipper - - - - - - - - - - - - Gly-zipper_Omp,OmpA,PD40 HSJS1_k127_112797_2 693986.MOC_4103 3.071e-05 56.0 COG5010@1|root,COG5010@2|Bacteria,1MVTK@1224|Proteobacteria,2TVBA@28211|Alphaproteobacteria,1JS1I@119045|Methylobacteriaceae 28211|Alphaproteobacteria U SMART Tetratricopeptide domain protein MA20_18455 - - - - - - - - - - - TPR_10,TPR_12,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 HSJS1_k127_112797_1 1242864.D187_007053 1.071e-06 60.0 COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg HSJS1_k127_112797_0 1168065.DOK_18960 2.711e-15 80.0 29NXS@1|root,309VX@2|Bacteria,1QT31@1224|Proteobacteria,1ST8H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1128895_1 1163409.UUA_15121 4.358e-98 340.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria,1X3EX@135614|Xanthomonadales 135614|Xanthomonadales P COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) yehZ - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC HSJS1_k127_1128895_2 1144275.COCOR_08068 3.231e-91 315.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,42SR8@68525|delta/epsilon subdivisions,2WPN0@28221|Deltaproteobacteria,2YUSS@29|Myxococcales 28221|Deltaproteobacteria S Histidine-specific methyltransferase, SAM-dependent - - 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 HSJS1_k127_1128895_0 1120797.KB908260_gene4073 5.7e-131 465.0 COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae 201174|Actinobacteria K involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein pknK_2 - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - AAA_22,GerE,NB-ARC,Pkinase,TPR_12 HSJS1_k127_1128895_3 1267535.KB906767_gene4499 2.344e-55 199.0 COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia 204432|Acidobacteriia K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_1135788_0 880072.Desac_2063 2.218e-77 269.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales 28221|Deltaproteobacteria BQ PFAM histone deacetylase superfamily - - - - - - - - - - - - Hist_deacetyl HSJS1_k127_1135788_2 682795.AciX8_1696 0.000722 51.0 COG1595@1|root,COG1595@2|Bacteria,3Y58Z@57723|Acidobacteria,2JN7R@204432|Acidobacteriia 204432|Acidobacteriia K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2 HSJS1_k127_1135788_1 1123242.JH636434_gene4961 2.826e-45 181.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes 203682|Planctomycetes P arylsulfatase A - - - - - - - - - - - - Sulfatase,TPR_16,TPR_19,TPR_2 HSJS1_k127_113816_2 1047013.AQSP01000106_gene1773 9.424e-20 103.0 COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria 2|Bacteria P Sulfatase - - - - - - - - - - - - Cu-binding_MopE,DUF4976,Sulfatase HSJS1_k127_113816_0 502025.Hoch_4498 8.865e-51 190.0 COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WS0J@28221|Deltaproteobacteria,2Z2ZP@29|Myxococcales 28221|Deltaproteobacteria FG HIT domain - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT HSJS1_k127_113816_3 105425.BBPL01000015_gene2660 5.852e-07 60.0 COG0028@1|root,COG3391@1|root,COG0028@2|Bacteria,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,2NFQM@228398|Streptacidiphilus 201174|Actinobacteria M IPT/TIG domain - - - - - - - - - - - - DUF11,HemolysinCabind,Lactonase,TIG HSJS1_k127_113816_1 1313172.YM304_41870 9.413e-24 104.0 2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - DUF3052 HSJS1_k127_1148514_1 197221.22295551 0.000148 51.0 COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria 1117|Cyanobacteria H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a HSJS1_k127_1148514_0 448385.sce0381 3.222e-28 123.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1150233_2 1210884.HG799464_gene11021 3.862e-07 59.0 COG1541@1|root,COG1541@2|Bacteria,2IWUR@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - - - - - - - - - - - HSJS1_k127_1150233_0 756272.Plabr_1285 4.629e-173 558.0 COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes 203682|Planctomycetes S PQQ-like domain - - - - - - - - - - - - PQQ_2,PQQ_3 HSJS1_k127_1150233_1 243090.RB7538 5.106e-51 191.0 COG1520@1|root,COG1520@2|Bacteria,2IX37@203682|Planctomycetes 203682|Planctomycetes S protein kinase related protein - - - - - - - - - - - - PQQ_2 HSJS1_k127_1166315_4 761193.Runsl_1400 1.331e-24 107.0 COG2368@1|root,COG2368@2|Bacteria,4NKNT@976|Bacteroidetes 976|Bacteroidetes Q 4-hydroxybutyryl-CoA dehydratase abfD - 4.2.1.120,5.3.3.3 ko:K14534 ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200 M00374,M00375 R03031,R10782 RC01857,RC03277 ko00000,ko00001,ko00002,ko01000 - - - HpaB,HpaB_N HSJS1_k127_1166315_1 1121930.AQXG01000018_gene756 4.601e-239 779.0 COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,1IR4H@117747|Sphingobacteriia 976|Bacteroidetes E peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - Peptidase_S9 HSJS1_k127_1166315_0 1242864.D187_008907 9.65e-254 799.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,42NBE@68525|delta/epsilon subdivisions,2WMG2@28221|Deltaproteobacteria,2YUJX@29|Myxococcales 28221|Deltaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 HSJS1_k127_1166315_5 1449976.KALB_4756 7.25e-06 58.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DYW9@85010|Pseudonocardiales 201174|Actinobacteria K DNA-binding transcriptional activator of the SARP family - - - - - - - - - - - - BTAD,NB-ARC,TPR_12,Trans_reg_C HSJS1_k127_1166315_2 1121346.KB899808_gene3433 2.362e-101 347.0 COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HBV3@91061|Bacilli,26RWE@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - - - - - - - - - - - Amidohydro_1 HSJS1_k127_1166315_3 1121448.DGI_2860 1.015e-40 155.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2M8X8@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 51 pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase HSJS1_k127_1172739_0 1123508.JH636444_gene5268 2.951e-253 796.0 COG0296@1|root,COG0296@2|Bacteria,2IXS1@203682|Planctomycetes 203682|Planctomycetes G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 HSJS1_k127_1172739_1 1121468.AUBR01000021_gene2827 1.899e-143 482.0 COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales 186801|Clostridia G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 HSJS1_k127_1172739_2 246197.MXAN_6387 4.59e-32 137.0 COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,2YVXN@29|Myxococcales 28221|Deltaproteobacteria S of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4 HSJS1_k127_1172739_3 526225.Gobs_2142 1.063e-26 120.0 COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales 201174|Actinobacteria S amine dehydrogenase activity - - - - - - - - - - - - - HSJS1_k127_1180317_0 926550.CLDAP_18370 4.592e-147 470.0 COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi 200795|Chloroflexi P PFAM Rhodanese domain protein - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese HSJS1_k127_1180317_3 671143.DAMO_2675 4.606e-18 86.0 2DSDZ@1|root,33FQR@2|Bacteria 2|Bacteria S Bacterial antitoxin of type II TA system, VapB - - - - - - - - - - - - VapB_antitoxin HSJS1_k127_1180317_1 1123504.JQKD01000012_gene1238 8.691e-53 189.0 COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria 1224|Proteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07064 - - - - ko00000 - - - PIN HSJS1_k127_1185978_2 1304885.AUEY01000087_gene92 1.645e-11 68.0 28PW7@1|root,32EDN@2|Bacteria,1N0AP@1224|Proteobacteria,42UF5@68525|delta/epsilon subdivisions,2WQ2P@28221|Deltaproteobacteria,2MKES@213118|Desulfobacterales 28221|Deltaproteobacteria S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 HSJS1_k127_1185978_0 338963.Pcar_3003 1.939e-201 656.0 COG1538@1|root,COG1538@2|Bacteria,1MYXE@1224|Proteobacteria,42TA7@68525|delta/epsilon subdivisions,2WR7T@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Outer membrane efflux protein - - - - - - - - - - - - OEP HSJS1_k127_1185978_1 338963.Pcar_3002 1.372e-96 340.0 COG0845@1|root,COG0845@2|Bacteria,1R443@1224|Proteobacteria,43A2V@68525|delta/epsilon subdivisions,2X238@28221|Deltaproteobacteria,43VF8@69541|Desulfuromonadales 28221|Deltaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 HSJS1_k127_1186238_1 1125863.JAFN01000001_gene1992 5.811e-44 164.0 COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria 28221|Deltaproteobacteria N Putative transposase, YhgA-like - - - - - - - - - - - - DUF4351,Transposase_31 HSJS1_k127_1186238_0 251221.35211765 1.989e-169 564.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_1188585_1 497964.CfE428DRAFT_5033 1.732e-130 426.0 COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia 74201|Verrucomicrobia H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - - - - - - - - - - - HSJS1_k127_1188585_0 1123508.JH636440_gene2677 1.109e-142 467.0 COG1012@1|root,COG1012@2|Bacteria,2IXUV@203682|Planctomycetes 203682|Planctomycetes C COG1012 NAD-dependent aldehyde - - - - - - - - - - - - Aldedh HSJS1_k127_1188585_2 1123508.JH636440_gene2678 1.189e-98 352.0 COG1454@1|root,COG1454@2|Bacteria,2IXD7@203682|Planctomycetes 203682|Planctomycetes C Iron-containing alcohol dehydrogenase - - 1.1.1.1 ko:K00001,ko:K13954 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH HSJS1_k127_1199260_2 1123368.AUIS01000020_gene1105 3.427e-42 175.0 COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,1T880@1236|Gammaproteobacteria,2NCF2@225057|Acidithiobacillales 225057|Acidithiobacillales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran HSJS1_k127_1199260_0 1047013.AQSP01000123_gene1542 1.564e-153 498.0 COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria 2|Bacteria T COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_1199260_1 1121413.JMKT01000011_gene2293 4.747e-95 331.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2M7YQ@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the peptidase S1C family degP - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 HSJS1_k127_1199996_3 1157637.KB892104_gene1719 4.662e-25 117.0 COG1020@1|root,COG1020@2|Bacteria,2I7R9@201174|Actinobacteria 201174|Actinobacteria Q Lantibiotic dehydratase, C terminus - - - - - - - - - - - - Lant_dehydr_N HSJS1_k127_1199996_1 3847.GLYMA19G31280.1 1.103e-86 324.0 COG0626@1|root,KOG0053@2759|Eukaryota,37HJ8@33090|Viridiplantae,3GEKB@35493|Streptophyta,4JGA4@91835|fabids 35493|Streptophyta E Cystathionine beta-lyase CBL GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019346,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0050667,GO:0070279,GO:0071265,GO:0071266,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP HSJS1_k127_1199996_0 1089439.KB902251_gene1630 3.86e-110 371.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,45ZYQ@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - - - - - - - - - - - Cys_Met_Meta_PP HSJS1_k127_1199996_2 1128421.JAGA01000002_gene1985 1.36e-51 198.0 COG0823@1|root,COG4995@1|root,COG0823@2|Bacteria,COG4995@2|Bacteria 2|Bacteria S CHAT domain - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - CHAT,PD40,WD40 HSJS1_k127_120071_4 880072.Desac_1768 3.971e-21 109.0 COG3307@1|root,COG3307@2|Bacteria,1Q2CU@1224|Proteobacteria,437Z3@68525|delta/epsilon subdivisions,2X391@28221|Deltaproteobacteria,2MSFW@213462|Syntrophobacterales 28221|Deltaproteobacteria M O-antigen ligase like membrane protein - - - - - - - - - - - - Wzy_C HSJS1_k127_120071_2 1047013.AQSP01000112_gene389 2.817e-48 185.0 COG1596@1|root,COG1596@2|Bacteria,2NPNM@2323|unclassified Bacteria 2|Bacteria M Polysaccharide export protein - - - ko:K01991,ko:K20988 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB HSJS1_k127_120071_0 1047013.AQSP01000112_gene392 2.897e-104 368.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria 2|Bacteria D CobQ CobB MinD ParA nucleotide binding domain ywqD - 2.7.10.1 ko:K08252,ko:K13661,ko:K16554,ko:K16692 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,ParA,Wzz HSJS1_k127_120071_3 401053.AciPR4_2191 2.678e-34 141.0 COG4464@1|root,COG4464@2|Bacteria,3Y4AS@57723|Acidobacteria,2JJ14@204432|Acidobacteriia 204432|Acidobacteriia GM protein tyrosine phosphatase activity - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - HSJS1_k127_120071_1 1232410.KI421414_gene2855 1.01e-89 302.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,43T7C@69541|Desulfuromonadales 28221|Deltaproteobacteria M Polysaccharide biosynthesis protein - - 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd HSJS1_k127_120400_0 264732.Moth_2048 1.099e-106 358.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,42F8R@68295|Thermoanaerobacterales 186801|Clostridia F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,GATase_5 HSJS1_k127_120400_1 1122239.AULS01000006_gene94 1.866e-25 124.0 COG1361@1|root,COG1361@2|Bacteria,2HFCG@201174|Actinobacteria,4FR1A@85023|Microbacteriaceae 201174|Actinobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 HSJS1_k127_120400_2 1248232.BANQ01000169_gene3304 3.272e-06 61.0 COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1XYT2@135623|Vibrionales 135623|Vibrionales S Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - FG-GAP_2 HSJS1_k127_1206194_1 266779.Meso_1188 0.0003037 48.0 COG1074@1|root,COG1074@2|Bacteria,1QUUZ@1224|Proteobacteria,2U7D7@28211|Alphaproteobacteria 28211|Alphaproteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 HSJS1_k127_1206194_0 1027273.GZ77_21105 1.232e-30 135.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT HSJS1_k127_1228831_2 1047013.AQSP01000124_gene2676 5.971e-94 341.0 COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria 2|Bacteria U Secretin and TonB N terminus short domain pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N HSJS1_k127_1228831_7 1499967.BAYZ01000068_gene1959 1.662e-05 55.0 COG3168@1|root,COG3168@2|Bacteria 2|Bacteria NU Pilus assembly protein, PilP pilP - - ko:K02664,ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP HSJS1_k127_1228831_4 1047013.AQSP01000124_gene2678 6.605e-25 113.0 COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria 2|Bacteria NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO HSJS1_k127_1228831_6 338963.Pcar_2137 3.289e-10 70.0 COG3166@1|root,COG3166@2|Bacteria,1Q1I2@1224|Proteobacteria,42VWH@68525|delta/epsilon subdivisions,2WS2H@28221|Deltaproteobacteria,43VGF@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Fimbrial assembly protein (PilN) - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN HSJS1_k127_1228831_1 1297742.A176_05319 1.689e-100 339.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales 28221|Deltaproteobacteria NU pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 HSJS1_k127_1228831_5 477974.Daud_0627 5.877e-15 83.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,262S5@186807|Peptococcaceae 186801|Clostridia J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 HSJS1_k127_1228831_0 555779.Dthio_PD0515 3.865e-202 654.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2M8QJ@213115|Desulfovibrionales 28221|Deltaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS HSJS1_k127_1228831_3 1267533.KB906734_gene4323 3.175e-49 179.0 COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia 204432|Acidobacteriia U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG HSJS1_k127_1228955_2 123899.JPQP01000001_gene1769 5.339e-95 336.0 COG0500@1|root,COG2226@2|Bacteria,1MV7N@1224|Proteobacteria,2VRBE@28216|Betaproteobacteria,3T5GT@506|Alcaligenaceae 28216|Betaproteobacteria H ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 HSJS1_k127_1228955_0 867903.ThesuDRAFT_02284 7.362e-170 572.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WCQQ@538999|Clostridiales incertae sedis 186801|Clostridia L UvrD/REP helicase N-terminal domain pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C HSJS1_k127_1228955_4 335543.Sfum_1870 1.382e-07 63.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales 28221|Deltaproteobacteria M PFAM Tetratricopeptide repeat - - - - - - - - - - - - PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 HSJS1_k127_1228955_3 1232410.KI421422_gene2065 6.584e-08 62.0 COG3266@1|root,COG3266@2|Bacteria,1N3DN@1224|Proteobacteria,42TS8@68525|delta/epsilon subdivisions,2WR5F@28221|Deltaproteobacteria,43SPH@69541|Desulfuromonadales 28221|Deltaproteobacteria S domain, Protein - - - - - - - - - - - - - HSJS1_k127_1228955_1 1125863.JAFN01000001_gene2253 8.92e-112 377.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_1233487_1 1183438.GKIL_3396 8.911e-51 188.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_ECF HSJS1_k127_1233487_0 589865.DaAHT2_1339 2.34e-79 284.0 COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2MI1U@213118|Desulfobacterales 28221|Deltaproteobacteria M PFAM peptidase - - - - - - - - - - - - Peptidase_M23 HSJS1_k127_1233487_2 1254432.SCE1572_42020 5.822e-12 76.0 COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria,2YVW2@29|Myxococcales 28221|Deltaproteobacteria E aminopeptidase N - - - - - - - - - - - - Peptidase_MA_2 HSJS1_k127_1254985_1 357808.RoseRS_0741 5.729e-26 114.0 COG0503@1|root,COG0503@2|Bacteria,2G8K9@200795|Chloroflexi,375M9@32061|Chloroflexia 32061|Chloroflexia F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran HSJS1_k127_1254985_0 573370.DMR_27120 1.025e-62 227.0 COG3409@1|root,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria,2MDFT@213115|Desulfovibrionales 28221|Deltaproteobacteria M peptidoglycan-binding domain-containing protein - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,VanY HSJS1_k127_125781_1 903818.KI912268_gene3366 6.008e-41 153.0 COG2018@1|root,COG2018@2|Bacteria 2|Bacteria K Roadblock/LC7 domain mglB - - - - - - - - - - - Robl_LC7 HSJS1_k127_125781_3 243231.GSU1339 1.897e-16 87.0 COG4393@1|root,COG4393@2|Bacteria,1R507@1224|Proteobacteria,42NQA@68525|delta/epsilon subdivisions,2WQ0C@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Predicted membrane protein (DUF2318) - - - - - - - - - - - - DUF2318 HSJS1_k127_125781_0 1122604.JONR01000018_gene1066 1.892e-174 574.0 COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QWC6@1224|Proteobacteria,1RPDJ@1236|Gammaproteobacteria,1X4ZV@135614|Xanthomonadales 135614|Xanthomonadales COT 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_7,Pyr_redox_3,cNMP_binding HSJS1_k127_125781_2 1123253.AUBD01000008_gene559 6.199e-29 128.0 29W19@1|root,30HJP@2|Bacteria,1R60N@1224|Proteobacteria,1S21W@1236|Gammaproteobacteria,1X6BC@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - HSJS1_k127_125781_4 1278073.MYSTI_02904 3.742e-08 61.0 COG1716@1|root,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination - - 4.6.1.1 ko:K01768,ko:K21397 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 - - DUF3662,FHA,Yop-YscD_cpl HSJS1_k127_125843_5 1000565.METUNv1_02581 1.513e-19 103.0 28IWG@1|root,2Z8US@2|Bacteria,1NHDW@1224|Proteobacteria,2VPYM@28216|Betaproteobacteria,2KY8N@206389|Rhodocyclales 206389|Rhodocyclales S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 HSJS1_k127_125843_2 338966.Ppro_2846 1.779e-77 274.0 28IWG@1|root,2Z8US@2|Bacteria,1NHDW@1224|Proteobacteria,42MHT@68525|delta/epsilon subdivisions,2WMMN@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 HSJS1_k127_125843_3 1068980.ARVW01000001_gene1774 2.226e-45 173.0 COG0500@1|root,COG2226@2|Bacteria,2IJ8Z@201174|Actinobacteria 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 HSJS1_k127_125843_0 266117.Rxyl_1562 1.92e-114 379.0 COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4CTCE@84995|Rubrobacteria 84995|Rubrobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N HSJS1_k127_125843_1 1157635.KB892010_gene1078 1.027e-113 388.0 COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria 201174|Actinobacteria O Carbamoyltransferase - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N HSJS1_k127_125843_4 56110.Oscil6304_2890 6.425e-28 118.0 COG2402@1|root,COG2402@2|Bacteria,1G5QP@1117|Cyanobacteria,1HF6X@1150|Oscillatoriales 1117|Cyanobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07065 - - - - ko00000 - - - PIN HSJS1_k127_1271438_0 756272.Plabr_3820 4.219e-147 485.0 COG2931@1|root,COG2931@2|Bacteria,2J53M@203682|Planctomycetes 203682|Planctomycetes C Animal haem peroxidase - - - - - - - - - - - - An_peroxidase HSJS1_k127_1271438_2 28072.Nos7524_1372 5.049e-11 75.0 COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G1WI@1117|Cyanobacteria 1117|Cyanobacteria Q PFAM Bacterial pre-peptidase C-terminal domain - - - - - - - - - - - - CARDB,Cadherin,Calx-beta,PPC HSJS1_k127_1271438_3 1280944.HY17_13165 2.898e-09 66.0 COG3350@1|root,COG3350@2|Bacteria,1RAI6@1224|Proteobacteria,2U6BK@28211|Alphaproteobacteria,43ZSF@69657|Hyphomonadaceae 28211|Alphaproteobacteria S monooxygenase activity - - - - - - - - - - - - YHS HSJS1_k127_1271438_1 251221.35211765 1.865e-78 278.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_1278499_2 399739.Pmen_0126 6.437e-13 79.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4 HSJS1_k127_1278499_0 1165841.SULAR_03802 1.679e-62 228.0 COG4564@1|root,COG4564@2|Bacteria,1N7NM@1224|Proteobacteria,42W17@68525|delta/epsilon subdivisions 1224|Proteobacteria T PFAM Cache - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - dCache_2,sCache_2 HSJS1_k127_1278499_1 671143.DAMO_2568 2.709e-44 163.0 COG1432@1|root,COG1432@2|Bacteria,2NQWI@2323|unclassified Bacteria 2|Bacteria S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH HSJS1_k127_1284349_1 926556.Echvi_3461 4.423e-16 93.0 2BZ4R@1|root,3344Z@2|Bacteria,4NX0J@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - HSJS1_k127_1284349_0 1122135.KB893146_gene1589 4.269e-107 355.0 COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,2TS6Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily MA20_39610 - - - - - - - - - - - EamA HSJS1_k127_1291828_0 1249627.D779_1330 1.898e-60 214.0 COG4636@1|root,COG4636@2|Bacteria,1RH5Y@1224|Proteobacteria,1S823@1236|Gammaproteobacteria,1WYPU@135613|Chromatiales 135613|Chromatiales S Putative restriction endonuclease - - - - - - - - - - - - Uma2 HSJS1_k127_1291828_1 1183438.GKIL_1809 5.961e-59 226.0 COG3488@1|root,COG3488@2|Bacteria,1G43T@1117|Cyanobacteria 1117|Cyanobacteria C Thiol oxidoreductase - - - - - - - - - - - - DHOR HSJS1_k127_1291828_3 208444.JNYY01000006_gene7371 2.432e-26 115.0 COG0346@1|root,COG0346@2|Bacteria,2H5Y5@201174|Actinobacteria,4EBMJ@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase HSJS1_k127_1291828_4 1047013.AQSP01000138_gene1074 6.478e-23 101.0 COG2337@1|root,COG2337@2|Bacteria 2|Bacteria T Toxic component of a toxin-antitoxin (TA) module mazF5 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin HSJS1_k127_1291828_2 1278073.MYSTI_01766 7.8e-33 133.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria 1224|Proteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_1295161_0 247490.KSU1_C1124 2.311e-17 96.0 COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2IZWB@203682|Planctomycetes 203682|Planctomycetes K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N HSJS1_k127_1295161_2 502025.Hoch_1897 2.345e-13 81.0 2EI76@1|root,33BYI@2|Bacteria,1NMIN@1224|Proteobacteria,42XUD@68525|delta/epsilon subdivisions,2WSV6@28221|Deltaproteobacteria,2Z2Z6@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1295161_1 1047013.AQSP01000072_gene985 1.644e-16 84.0 COG1426@1|root,COG1426@2|Bacteria,2NQ7E@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4115) - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 HSJS1_k127_1296499_3 649638.Trad_2597 1.312e-35 139.0 COG0042@1|root,COG0042@2|Bacteria,1WJ8R@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus HSJS1_k127_1296499_2 1499967.BAYZ01000176_gene5630 3.327e-79 280.0 COG0564@1|root,COG0564@2|Bacteria 2|Bacteria J pseudouridine synthase activity rluA - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 HSJS1_k127_1296499_0 378806.STAUR_8391 4.355e-165 539.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2X3TP@28221|Deltaproteobacteria,2YX2Z@29|Myxococcales 28221|Deltaproteobacteria OU Peptidase family S49 - - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 HSJS1_k127_1296499_1 1123023.JIAI01000015_gene3318 9.812e-97 323.0 COG0212@1|root,COG0212@2|Bacteria,2GM4X@201174|Actinobacteria,4E2I3@85010|Pseudonocardiales 201174|Actinobacteria H PFAM 5-formyltetrahydrofolate cyclo-ligase - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig HSJS1_k127_1296499_5 1396858.Q666_10205 5.351e-20 94.0 COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,467S1@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS HSJS1_k127_12967_3 1192034.CAP_7265 1.383e-08 67.0 COG1012@1|root,COG1012@2|Bacteria 2|Bacteria C belongs to the aldehyde dehydrogenase family - - - - - - - - - - - - - HSJS1_k127_12967_0 1267535.KB906767_gene4448 4.565e-39 169.0 COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia 204432|Acidobacteriia S PFAM von Willebrand factor type A - - - - - - - - - - - - VWA,VWA_2,VWA_3 HSJS1_k127_12967_2 1047013.AQSP01000088_gene1632 5.349e-12 80.0 COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NR7I@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - BatD,TPR_16,TPR_2,TPR_6,TPR_8 HSJS1_k127_12967_1 234267.Acid_4462 2.118e-31 134.0 2DBZ3@1|root,2ZBZB@2|Bacteria,3Y93R@57723|Acidobacteria 57723|Acidobacteria S Protein of unknown function (DUF3298) - - - - - - - - - - - - DUF3298 HSJS1_k127_1297096_2 1184267.A11Q_881 6.845e-08 58.0 2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2MUBY@213481|Bdellovibrionales,2WRKE@28221|Deltaproteobacteria 213481|Bdellovibrionales S Domain of unknown function (DUF1844) - - - - - - - - - - - - DUF1844 HSJS1_k127_1297096_3 713587.THITH_03175 0.000202 54.0 COG0457@1|root,COG0457@2|Bacteria,1QW7M@1224|Proteobacteria 1224|Proteobacteria U Tetratricopeptide repeats - - - - - - - - - - - - Asp_protease_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 HSJS1_k127_1297096_1 1242864.D187_004746 4.741e-17 94.0 COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388 HSJS1_k127_1297096_0 204669.Acid345_0982 9.933e-76 259.0 COG0443@1|root,COG0443@2|Bacteria,3Y2XU@57723|Acidobacteria,2JHT1@204432|Acidobacteriia 204432|Acidobacteriia O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 HSJS1_k127_1298266_9 1121104.AQXH01000001_gene1481 2.002e-05 55.0 COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IX1Y@117747|Sphingobacteriia 976|Bacteroidetes O cytochrome C ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm HSJS1_k127_1298266_2 1047013.AQSP01000033_gene1389 1.254e-66 236.0 COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria 2|Bacteria T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 HSJS1_k127_1298266_5 391613.RTM1035_09134 5.893e-28 121.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,46PBA@74030|Roseovarius 28211|Alphaproteobacteria H Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI HSJS1_k127_1298266_1 945713.IALB_0655 9.54e-150 489.0 COG0733@1|root,COG0733@2|Bacteria 2|Bacteria S neurotransmitter:sodium symporter activity CP_0468 - - ko:K03308,ko:K03466 - - - - ko00000,ko03036 2.A.22.4,2.A.22.5,3.A.12 - - SNF HSJS1_k127_1298266_4 682795.AciX8_1564 1.768e-29 133.0 COG0352@1|root,COG0352@2|Bacteria,3Y4Y5@57723|Acidobacteria,2JJM3@204432|Acidobacteriia 204432|Acidobacteriia H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI HSJS1_k127_1298266_0 518766.Rmar_0675 1.098e-180 576.0 COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1FJ47@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes I Biotin carboxylase C-terminal domain accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 HSJS1_k127_1298266_3 262724.TT_C0759 1.742e-29 124.0 COG0511@1|root,COG0511@2|Bacteria,1WJNN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl HSJS1_k127_1298266_7 765420.OSCT_0828 1.656e-07 58.0 COG2018@1|root,COG2018@2|Bacteria,2GB8V@200795|Chloroflexi,377K6@32061|Chloroflexia 32061|Chloroflexia S Roadblock/LC7 domain - - - - - - - - - - - - Robl_LC7 HSJS1_k127_1298266_8 862908.BMS_0132 1.964e-05 57.0 COG0457@1|root,COG0457@2|Bacteria,1NEMW@1224|Proteobacteria,42WBX@68525|delta/epsilon subdivisions,2MTCS@213481|Bdellovibrionales,2WRAD@28221|Deltaproteobacteria 213481|Bdellovibrionales NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_8 HSJS1_k127_1298266_6 1410619.SRDD_44820 2.416e-10 72.0 COG2911@1|root,COG2911@2|Bacteria,1QUF3@1224|Proteobacteria,1T1WM@1236|Gammaproteobacteria,404HW@613|Serratia 1236|Gammaproteobacteria S Bacterial Ig-like domain (group 1) - - - ko:K13735 ko05100,map05100 - - - ko00000,ko00001 - - - Big_1,IAT_beta,Invasin_D3 HSJS1_k127_1306525_0 215803.DB30_8135 1.196e-28 123.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42UEE@68525|delta/epsilon subdivisions,2WQHS@28221|Deltaproteobacteria 28221|Deltaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX HSJS1_k127_1316537_0 1124780.ANNU01000048_gene2140 2.299e-117 386.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KU8@768503|Cytophagia 976|Bacteroidetes J Amidase - - - - - - - - - - - - Amidase HSJS1_k127_1316537_1 518766.Rmar_1532 1.259e-28 130.0 COG4244@1|root,COG4244@2|Bacteria,4PF9S@976|Bacteroidetes,1FKC3@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Membrane - - - - - - - - - - - - - HSJS1_k127_1316537_2 1430440.MGMSRv2_1178 5.665e-07 55.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 HSJS1_k127_1318231_1 879212.DespoDRAFT_03161 1.77e-80 273.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2MI4Q@213118|Desulfobacterales 28221|Deltaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA HSJS1_k127_1318231_0 1303518.CCALI_00571 2.613e-84 296.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_1318778_0 1278073.MYSTI_01766 1.589e-112 396.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria 1224|Proteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_1318778_1 861299.J421_0639 1.455e-34 138.0 COG1695@1|root,COG1695@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - PadR HSJS1_k127_1325474_0 1089550.ATTH01000001_gene738 8.912e-147 484.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FINA@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Transketolase, pyrimidine binding domain bfmBA - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C HSJS1_k127_1325474_2 266117.Rxyl_0601 1.482e-12 79.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria 201174|Actinobacteria O PFAM peptidase S1 and S6, chymotrypsin Hap - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 HSJS1_k127_1325474_1 1449126.JQKL01000043_gene1887 7.104e-24 113.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,268PT@186813|unclassified Clostridiales 186801|Clostridia K ECF sigma factor algU - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_1326809_0 1267535.KB906767_gene5001 4.957e-62 231.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Cu-binding_MopE,Sulfatase HSJS1_k127_1331197_2 909663.KI867151_gene3132 1.948e-64 244.0 COG0774@1|root,COG2204@1|root,COG0774@2|Bacteria,COG2204@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,2MRFZ@213462|Syntrophobacterales 28221|Deltaproteobacteria MT UDP-3-O-acyl N-acetylglycosamine deacetylase lpxC - 3.5.1.108 ko:K02535,ko:K13599 ko00540,ko01100,ko02020,map00540,map01100,map02020 M00060,M00498 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005,ko02022 - - - LpxC HSJS1_k127_1331197_1 583355.Caka_1355 1.561e-83 292.0 COG0654@1|root,COG0654@2|Bacteria,46VIV@74201|Verrucomicrobia 74201|Verrucomicrobia CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 HSJS1_k127_1331197_0 309801.trd_0495 1.451e-155 497.0 COG2225@1|root,COG2225@2|Bacteria,2G63R@200795|Chloroflexi,27Y0V@189775|Thermomicrobia 189775|Thermomicrobia C Malate synthase - - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase HSJS1_k127_1331203_0 483219.LILAB_10590 9.99e-82 297.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales 28221|Deltaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_10,TPR_12,zf-HC2 HSJS1_k127_1331413_1 880073.Calab_2556 3.399e-26 110.0 COG3251@1|root,COG3251@2|Bacteria,2NRE2@2323|unclassified Bacteria 2|Bacteria S MbtH-like protein - - - ko:K05375,ko:K09190 ko00261,ko01130,map00261,map01130 M00736 R10880 RC00064,RC00141,RC03296,RC03297,RC03298 ko00000,ko00001,ko00002 - - - MbtH,YqcI_YcgG HSJS1_k127_1331413_0 344747.PM8797T_02644 1.584e-109 365.0 COG0530@1|root,COG0530@2|Bacteria 2|Bacteria P calcium, potassium:sodium antiporter activity yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex HSJS1_k127_1331413_2 452638.Pnec_1302 1.919e-09 63.0 2DQE9@1|root,32UNX@2|Bacteria,1NZT3@1224|Proteobacteria,2W30X@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1335994_1 478741.JAFS01000002_gene60 3.862e-72 253.0 COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,37G41@326457|unclassified Verrucomicrobia 2|Bacteria L Bacterial DNA polymerase III alpha subunit dnaE2 - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon HSJS1_k127_1335994_0 109760.SPPG_04804T0 3.623e-125 411.0 COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi 4751|Fungi Q Dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N HSJS1_k127_1335994_2 675635.Psed_5174 5.458e-05 49.0 2AQY0@1|root,31G6M@2|Bacteria,2IEYJ@201174|Actinobacteria,4DY1Q@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - HSJS1_k127_134249_0 926569.ANT_25310 2.938e-35 147.0 COG1996@1|root,COG1996@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - DUF4379 HSJS1_k127_1349943_4 290318.Cvib_0206 4.947e-11 66.0 COG0803@1|root,COG0803@2|Bacteria,1FEDW@1090|Chlorobi 1090|Chlorobi P PFAM periplasmic solute binding protein - - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA HSJS1_k127_1349943_2 326427.Cagg_2434 4.879e-55 204.0 COG1122@1|root,COG1122@2|Bacteria,2G6FK@200795|Chloroflexi,37779@32061|Chloroflexia 32061|Chloroflexia P ECF transporter, substrate-specific component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF_trnsprt HSJS1_k127_1349943_0 926550.CLDAP_33520 1.479e-135 466.0 COG1129@1|root,COG1129@2|Bacteria,2GBJG@200795|Chloroflexi 200795|Chloroflexi G ATPases associated with a variety of cellular activities - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran HSJS1_k127_1349943_3 1128421.JAGA01000002_gene228 1.952e-42 170.0 COG0619@1|root,COG0619@2|Bacteria 2|Bacteria P transmembrane transporter activity - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K16783,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ HSJS1_k127_1349943_1 1333998.M2A_1070 1.286e-86 297.0 COG3386@1|root,COG3386@2|Bacteria,1NIN4@1224|Proteobacteria,2U3KK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Major royal jelly protein - - - - - - - - - - - - MRJP HSJS1_k127_1350627_3 1380393.JHVP01000005_gene3591 6.066e-85 294.0 COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria,4EWIE@85013|Frankiales 201174|Actinobacteria S Putative esterase - - - - - - - - - - - - Esterase HSJS1_k127_1350627_0 1246995.AFR_24945 2.754e-119 399.0 COG1181@1|root,COG1181@2|Bacteria,2HP1M@201174|Actinobacteria,4DHKT@85008|Micromonosporales 201174|Actinobacteria M Belongs to the D-alanine--D-alanine ligase family - - - - - - - - - - - - Dala_Dala_lig_C HSJS1_k127_1350627_1 1300345.LF41_1328 1.828e-108 366.0 COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,1TJ90@1236|Gammaproteobacteria,1X98N@135614|Xanthomonadales 135614|Xanthomonadales S Alpha/beta hydrolase of unknown function (DUF900) - - - - - - - - - - - - DUF900 HSJS1_k127_1350627_2 1122622.ATWJ01000008_gene2999 3.023e-102 345.0 COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria,4FE3S@85021|Intrasporangiaceae 201174|Actinobacteria P Putative esterase - - - ko:K07214 - - - - ko00000 - - - DUF3327,Esterase HSJS1_k127_1350627_6 595460.RRSWK_05347 2.683e-08 66.0 2C40J@1|root,33272@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_1350627_4 1128421.JAGA01000001_gene2142 1.346e-82 293.0 COG0665@1|root,COG0665@2|Bacteria,2NRPW@2323|unclassified Bacteria 2|Bacteria E FAD dependent oxidoreductase - - 1.4.3.3 ko:K00273 ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146 - R00366,R02457,R02894,R02923,R04221,R07400 RC00006,RC00018,RC00135 ko00000,ko00001,ko01000 - - - DAO HSJS1_k127_1350627_5 1232410.KI421421_gene3825 4.046e-63 222.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales 28221|Deltaproteobacteria V AcrB/AcrD/AcrF family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_1352011_1 443143.GM18_3746 5.444e-14 78.0 COG0457@1|root,COG0457@2|Bacteria 443143.GM18_3746|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_1352011_0 1283300.ATXB01000001_gene2312 1.255e-32 132.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1XH0W@135618|Methylococcales 135618|Methylococcales P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 HSJS1_k127_1354974_0 575540.Isop_2750 1.522e-101 349.0 COG2041@1|root,COG3876@1|root,COG2041@2|Bacteria,COG3876@2|Bacteria,2J50E@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF1343) - - - - - - - - - - - - DUF1343 HSJS1_k127_1354974_1 67373.JOBF01000039_gene3688 1.09e-48 179.0 COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria 201174|Actinobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC HSJS1_k127_1358051_5 751945.Theos_0271 7.688e-05 55.0 COG1470@1|root,COG3895@1|root,COG1470@2|Bacteria,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM PEGA domain - - - - - - - - - - - - DUF4384,PEGA HSJS1_k127_1358051_4 748658.KB907321_gene806 4.586e-08 59.0 COG1309@1|root,COG1309@2|Bacteria,1N8IR@1224|Proteobacteria,1SE8V@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K18939 - M00715 - - ko00000,ko00002,ko03000 - - - TetR_C_13,TetR_N HSJS1_k127_1358051_2 1396418.BATQ01000041_gene6330 4.878e-19 97.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia,2IVPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 HSJS1_k127_1358051_0 180281.CPCC7001_2156 6.358e-189 605.0 COG0457@1|root,COG0457@2|Bacteria,1GDHI@1117|Cyanobacteria,22TVE@167375|Cyanobium 1117|Cyanobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - - HSJS1_k127_1358051_3 1116375.VEJY3_08085 3.949e-13 78.0 29PJW@1|root,30AI1@2|Bacteria,1RD86@1224|Proteobacteria,1S5B8@1236|Gammaproteobacteria,1XU7H@135623|Vibrionales 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4268 HSJS1_k127_1358051_1 391587.KAOT1_05907 1.961e-41 173.0 COG1816@1|root,COG1816@2|Bacteria,4NINN@976|Bacteroidetes,1I83N@117743|Flavobacteriia 976|Bacteroidetes F Adenosine/AMP deaminase - - - - - - - - - - - - A_deaminase HSJS1_k127_1359630_2 1267533.KB906735_gene4585 3.175e-76 261.0 COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia 204432|Acidobacteriia C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C HSJS1_k127_1359630_1 204669.Acid345_1385 1.769e-120 403.0 COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia 204432|Acidobacteriia C 2Fe-2S iron-sulfur cluster binding domain - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 HSJS1_k127_1359630_4 204669.Acid345_1386 1.154e-43 164.0 2EDAV@1|root,33776@2|Bacteria,3Y8RG@57723|Acidobacteria,2JNHN@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - HSJS1_k127_1359630_0 1089550.ATTH01000001_gene1831 4.313e-153 518.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_1359630_3 234267.Acid_7677 9.436e-58 207.0 COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria 57723|Acidobacteria K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_1359630_5 529709.PYCH_04820 1.996e-05 56.0 arCOG11399@1|root,arCOG11399@2157|Archaea,2Y6N1@28890|Euryarchaeota,244XG@183968|Thermococci 183968|Thermococci S Caspase domain - - - - - - - - - - - - Peptidase_C14 HSJS1_k127_1360707_0 1267533.KB906734_gene3960 2.592e-251 811.0 COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia 204432|Acidobacteriia L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF HSJS1_k127_1361644_1 448385.sce5399 7.892e-33 135.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YWRH@29|Myxococcales 28221|Deltaproteobacteria L OB-fold nucleic acid binding domain - - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 HSJS1_k127_1361644_3 1246995.AFR_41630 1.301e-10 76.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4D9YU@85008|Micromonosporales 201174|Actinobacteria T PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,Guanylate_cyc,TPR_12 HSJS1_k127_1361644_4 1463887.KL590049_gene1714 1.38e-05 59.0 COG0457@1|root,COG0457@2|Bacteria,2GK6N@201174|Actinobacteria 201174|Actinobacteria L Tetratricopeptide repeat - - - - - - - - - - - - NB-ARC,TPR_12,TPR_7 HSJS1_k127_1361644_0 1460640.JCM19046_4023 8.793e-34 144.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 HSJS1_k127_1361644_2 240015.ACP_1808 1.473e-13 77.0 COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia 204432|Acidobacteriia S PFAM von Willebrand factor type A - - - - - - - - - - - - VWA,VWA_2,VWA_3 HSJS1_k127_1368517_1 246197.MXAN_2206 1.461e-82 292.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,42UA0@68525|delta/epsilon subdivisions,2WS4D@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - CHAT,TPR_12,TPR_7 HSJS1_k127_1368517_0 251229.Chro_1371 2.072e-189 614.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1G092@1117|Cyanobacteria,3VHVP@52604|Pleurocapsales 1117|Cyanobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt HSJS1_k127_1375762_1 1267535.KB906767_gene468 2.844e-60 238.0 COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria 57723|Acidobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,TonB_dep_Rec HSJS1_k127_1375762_2 247634.GPB2148_522 2.787e-43 173.0 COG1073@1|root,COG1073@2|Bacteria,1NEVB@1224|Proteobacteria 1224|Proteobacteria S alpha beta - - - - - - - - - - - - - HSJS1_k127_1375762_0 1121033.AUCF01000046_gene545 6.07e-99 349.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2JPUZ@204441|Rhodospirillales 204441|Rhodospirillales CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 HSJS1_k127_1375762_3 1303518.CCALI_02307 2.496e-14 85.0 COG4232@1|root,COG4232@2|Bacteria 2|Bacteria CO protein-disulfide reductase activity - - - - - - - - - - - - TPR_6,Thioredoxin_7 HSJS1_k127_1378520_4 1047013.AQSP01000085_gene1984 3.259e-15 85.0 COG2165@1|root,COG2165@2|Bacteria 2|Bacteria NU general secretion pathway protein - - - ko:K02456,ko:K02650 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - N_methyl,Pilin_GH,Pilin_PilA HSJS1_k127_1378520_1 331869.BAL199_10435 1.479e-48 185.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,4BQCP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase HSJS1_k127_1378520_5 1509405.GV67_16185 5.683e-10 71.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,4BAIQ@82115|Rhizobiaceae 28211|Alphaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N HSJS1_k127_1378520_0 1068978.AMETH_0419 8.005e-88 307.0 COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4DYP8@85010|Pseudonocardiales 201174|Actinobacteria S Short-chain alcohol dehydrogenase sdh GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.381 ko:K16066 ko00240,ko00260,ko01100,map00240,map00260,map01100 - R09289,R10851,R10852 RC00087,RC00525,RC03288 ko00000,ko00001,ko01000 - - - adh_short HSJS1_k127_1378520_2 371731.Rsw2DRAFT_1930 1.413e-37 150.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2TTX4@28211|Alphaproteobacteria,1FBVN@1060|Rhodobacter 28211|Alphaproteobacteria K Belongs to the UPF0301 (AlgH) family MA20_18155 - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 HSJS1_k127_1378520_3 1521187.JPIM01000083_gene3847 1.345e-19 91.0 COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,374T1@32061|Chloroflexia 32061|Chloroflexia C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C HSJS1_k127_1379500_0 234267.Acid_5856 2.509e-72 263.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase HSJS1_k127_138003_0 452637.Oter_0526 1.933e-55 207.0 COG0457@1|root,COG2755@1|root,COG0457@2|Bacteria,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N,Lipase_GDSL_2,SLH,TPR_16,TPR_19,fn3 HSJS1_k127_138003_1 1121448.DGI_2904 1.252e-40 160.0 COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WJYG@28221|Deltaproteobacteria,2M807@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM periplasmic solute binding protein - - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA HSJS1_k127_1383213_0 251221.35211765 7.217e-187 612.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_1383213_2 644282.Deba_1505 5.682e-135 448.0 COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria 28221|Deltaproteobacteria C PFAM FAD linked oxidase domain protein - - 2.5.1.26 ko:K00803 ko00565,ko01100,ko04146,map00565,map01100,map04146 - R04311 RC00020,RC02886 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 HSJS1_k127_1383213_3 1123256.KB907926_gene759 2.025e-86 321.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X4EH@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C HSJS1_k127_1383213_4 1131269.AQVV01000001_gene1450 2.002e-60 220.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity mhpC - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 HSJS1_k127_1383213_1 997346.HMPREF9374_0882 6.805e-149 485.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,27BFU@186824|Thermoactinomycetaceae 91061|Bacilli U SRP54-type protein, GTPase domain ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB HSJS1_k127_1383213_5 338963.Pcar_0532 2.018e-18 85.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,43TYM@69541|Desulfuromonadales 28221|Deltaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 HSJS1_k127_1404629_1 1210884.HG799462_gene8069 5.772e-24 108.0 COG0300@1|root,COG0300@2|Bacteria,2J0SJ@203682|Planctomycetes 203682|Planctomycetes S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short HSJS1_k127_1404629_2 311403.Arad_3254 2.355e-14 78.0 COG0346@1|root,COG0346@2|Bacteria,1NJ3K@1224|Proteobacteria,2UM27@28211|Alphaproteobacteria,4BDQN@82115|Rhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase HSJS1_k127_1404629_0 360910.BAV1203 2.27e-163 531.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,3T1QD@506|Alcaligenaceae 28216|Betaproteobacteria C E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr HSJS1_k127_1416154_1 439235.Dalk_1929 3.481e-159 522.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MJ3U@213118|Desulfobacterales 28221|Deltaproteobacteria M Lytic transglycosylase catalytic mltD2 - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT HSJS1_k127_1416154_0 518766.Rmar_2224 3.259e-203 643.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt HSJS1_k127_1424349_0 869210.Marky_1958 5.571e-224 706.0 COG1866@1|root,COG1866@2|Bacteria,1WIQ3@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP HSJS1_k127_1424349_4 713587.THITH_11295 2.937e-18 87.0 COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,1SJ4Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin HSJS1_k127_1424349_1 1123368.AUIS01000023_gene933 7.547e-181 597.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 HSJS1_k127_1424349_2 398767.Glov_2997 4.762e-35 142.0 COG2050@1|root,COG2050@2|Bacteria,1NHB0@1224|Proteobacteria,42XCC@68525|delta/epsilon subdivisions,2WTEP@28221|Deltaproteobacteria,43UMX@69541|Desulfuromonadales 28221|Deltaproteobacteria Q Thioesterase superfamily - - - - - - - - - - - - 4HBT HSJS1_k127_1424349_3 292459.STH644 7.533e-34 142.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia 186801|Clostridia KT Sigma-54 interaction domain prdR - - ko:K06714 - - - - ko00000,ko03000 - - - CBS,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat HSJS1_k127_1426211_3 251221.35211463 3.183e-42 165.0 COG1836@1|root,COG1836@2|Bacteria,1G07R@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - - - - - - - - - - DUF92 HSJS1_k127_1426211_5 1444309.JAQG01000105_gene326 1.77e-26 119.0 COG3339@1|root,COG3339@2|Bacteria,1V6NW@1239|Firmicutes,4HJQR@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 HSJS1_k127_1426211_4 1142394.PSMK_26760 3.77e-40 162.0 COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes 203682|Planctomycetes S SCO1/SenC - - - ko:K07152,ko:K08976 - - - - ko00000,ko03029 - - - DUF420,SCO1-SenC HSJS1_k127_1426211_2 314230.DSM3645_19568 5.95e-62 225.0 COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes 203682|Planctomycetes V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane HSJS1_k127_1426211_0 204669.Acid345_2220 2.499e-86 296.0 COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia 204432|Acidobacteriia V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_1426211_1 1267535.KB906767_gene1277 1.908e-81 282.0 COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia 204432|Acidobacteriia O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA HSJS1_k127_1430404_2 292459.STH3191 4.225e-53 194.0 COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia 186801|Clostridia Q Belongs to the metallo-dependent hydrolases superfamily. HutI family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 HSJS1_k127_1430404_1 1120948.KB903219_gene651 5.136e-107 362.0 COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DYUI@85010|Pseudonocardiales 201174|Actinobacteria C aldo keto reductase - - 1.1.1.91 ko:K05882 - - - - ko00000,ko01000 - - - Aldo_ket_red HSJS1_k127_1430404_3 446470.Snas_3258 5.066e-12 78.0 COG4733@1|root,COG4733@2|Bacteria,2I3TX@201174|Actinobacteria 201174|Actinobacteria G Protein of unknown function (DUF2961) - - - - - - - - - - - - DUF2961 HSJS1_k127_1430404_0 1278073.MYSTI_06643 4.821e-154 496.0 COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,42T8N@68525|delta/epsilon subdivisions 1224|Proteobacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 HSJS1_k127_1437761_1 1382356.JQMP01000003_gene2430 2.188e-74 266.0 COG1363@1|root,COG1363@2|Bacteria,2GAAU@200795|Chloroflexi,27YY7@189775|Thermomicrobia 189775|Thermomicrobia G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 HSJS1_k127_1437761_0 502025.Hoch_4422 1.133e-94 313.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,43B5T@68525|delta/epsilon subdivisions,2X6JE@28221|Deltaproteobacteria,2Z3BD@29|Myxococcales 28221|Deltaproteobacteria C Inorganic pyrophosphatase - - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase HSJS1_k127_1437761_5 234267.Acid_4263 4.073e-16 91.0 COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria 2|Bacteria S PFAM von Willebrand factor type A - - - ko:K07114,ko:K12511 - - - - ko00000,ko02000,ko02044 1.A.13.2.2,1.A.13.2.3 - - FHA,VWA,VWA_2 HSJS1_k127_1437761_8 309807.SRU_1584 3.023e-07 64.0 COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Anaphase-promoting complex, cyclosome, subunit 3 - - - - - - - - - - - - TPR_16,TPR_2,TPR_21,TPR_6,TPR_8 HSJS1_k127_1437761_7 204669.Acid345_0913 9.801e-10 72.0 COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia 204432|Acidobacteriia S oxidoreductase activity - - - - - - - - - - - - - HSJS1_k127_1437761_4 1453501.JELR01000002_gene329 7.431e-39 160.0 COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8,Transglut_core HSJS1_k127_1437761_2 644282.Deba_0033 4.971e-58 210.0 COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,42VV4@68525|delta/epsilon subdivisions,2WRNK@28221|Deltaproteobacteria 28221|Deltaproteobacteria K FCD - - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR HSJS1_k127_1437761_3 502025.Hoch_6822 2.816e-41 168.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,430Q4@68525|delta/epsilon subdivisions,2WVN2@28221|Deltaproteobacteria,2Z0IB@29|Myxococcales 28221|Deltaproteobacteria D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 HSJS1_k127_1441689_0 439235.Dalk_3089 1.513e-67 246.0 2A102@1|root,30P5F@2|Bacteria,1NQ9E@1224|Proteobacteria,433GU@68525|delta/epsilon subdivisions,2WXXA@28221|Deltaproteobacteria 1224|Proteobacteria S IMG reference gene - - - - - - - - - - - - DUF3592 HSJS1_k127_1441689_2 756067.MicvaDRAFT_1230 8.377e-58 226.0 COG1957@1|root,COG1957@2|Bacteria,1G231@1117|Cyanobacteria,1H9TZ@1150|Oscillatoriales 1117|Cyanobacteria F PFAM Inosine uridine-preferring nucleoside hydrolase - - 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro HSJS1_k127_1441689_1 306281.AJLK01000102_gene3405 1.008e-61 235.0 COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria 1117|Cyanobacteria S MOSC domain - - - - - - - - - - - - - HSJS1_k127_1441689_3 1463861.JNXE01000006_gene5563 0.0008789 47.0 2F592@1|root,33XVA@2|Bacteria,2I07S@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (DUF2690) - - - - - - - - - - - - DUF2690,HTH_31 HSJS1_k127_1450900_4 1142394.PSMK_06260 1.122e-05 57.0 COG0308@1|root,COG0308@2|Bacteria 2|Bacteria E peptide catabolic process - - - - - - - - - - - - Peptidase_MA_2 HSJS1_k127_1450900_3 1122201.AUAZ01000003_gene1974 2.504e-30 134.0 COG1577@1|root,COG1577@2|Bacteria,1RIKN@1224|Proteobacteria,1S678@1236|Gammaproteobacteria 1236|Gammaproteobacteria I GHMP kinases N terminal domain - - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N HSJS1_k127_1450900_0 797210.Halxa_1856 5.562e-109 367.0 COG1257@1|root,arCOG04260@2157|Archaea,2XTV9@28890|Euryarchaeota,23S4F@183963|Halobacteria 183963|Halobacteria I Belongs to the HMG-CoA reductase family hmgA - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red HSJS1_k127_1450900_1 326427.Cagg_0435 2.473e-102 345.0 COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi,374UE@32061|Chloroflexia 32061|Chloroflexia H Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh HSJS1_k127_1450900_2 58123.JOFJ01000001_gene3125 8.053e-63 232.0 COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4EFMM@85012|Streptosporangiales 201174|Actinobacteria H Belongs to the FPP GGPP synthase family idsA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt HSJS1_k127_1452657_1 443144.GM21_3561 8.541e-51 198.0 COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K13735,ko:K20276 ko02024,ko05100,map02024,map05100 - - - ko00000,ko00001 - - - Big_2,CarboxypepD_reg,DUF11,DUF3494,SdrD_B HSJS1_k127_1452657_2 316067.Geob_0053 2.795e-48 193.0 COG0484@1|root,COG3880@1|root,COG0484@2|Bacteria,COG3880@2|Bacteria 2|Bacteria E PFAM UvrB UvrC protein mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K08999,ko:K19405,ko:K19411 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - Cytochrom_CIII,Cytochrome_C7,UVR HSJS1_k127_1452657_4 443143.GM18_0597 6.567e-33 147.0 COG1333@1|root,COG1333@2|Bacteria 2|Bacteria O cytochrome c biogenesis protein resB - - ko:K07399 - - - - ko00000 - - - ResB HSJS1_k127_1452657_0 443144.GM21_3558 1.749e-82 283.0 COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm HSJS1_k127_1452657_5 443144.GM21_3557 4.093e-22 109.0 COG1333@1|root,COG1333@2|Bacteria 2|Bacteria O cytochrome c biogenesis protein resB - - ko:K07399 - - - - ko00000 - - - ResB HSJS1_k127_1452657_6 635013.TherJR_1027 2.654e-13 83.0 COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,24BCK@186801|Clostridia,260YW@186807|Peptococcaceae 186801|Clostridia O PFAM Cytochrome c assembly protein ccsB - - - - - - - - - - - Cytochrom_C_asm HSJS1_k127_1452657_3 443143.GM18_0607 1.024e-39 153.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria 28221|Deltaproteobacteria C SMART Elongator protein 3 MiaB NifB - - 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 - - - B12-binding,Radical_SAM HSJS1_k127_1461930_1 1384056.N787_06875 4.311e-84 287.0 arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - HSJS1_k127_1461930_0 926569.ANT_27970 1.381e-153 524.0 COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - 3.4.21.50,3.4.24.28 ko:K01337,ko:K01400,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF4968,DUF5110,F5_F8_type_C,FTP,Glyco_hydro_31,PA,Peptidase_M4,Peptidase_M4_C,Peptidase_M6,Peptidase_S8,W_rich_C HSJS1_k127_1461930_3 502025.Hoch_1983 9.176e-17 82.0 2DREH@1|root,33BDY@2|Bacteria,1Q6K1@1224|Proteobacteria,433AU@68525|delta/epsilon subdivisions,2WXFM@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1461930_2 502025.Hoch_1982 1.685e-46 173.0 COG1978@1|root,COG1978@2|Bacteria 2|Bacteria S oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor prdB - 1.21.4.1,1.21.4.2 ko:K10672,ko:K10794 ko00330,map00330 - R02825 RC00790 ko00000,ko00001,ko01000 - - - GRDB HSJS1_k127_1461930_4 1144275.COCOR_07072 1.839e-16 84.0 2AQ29@1|root,31F7C@2|Bacteria,1NHC1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1466559_2 765869.BDW_11300 8.112e-42 164.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2MTE2@213481|Bdellovibrionales,2WRSP@28221|Deltaproteobacteria 213481|Bdellovibrionales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 HSJS1_k127_1466559_0 1184267.A11Q_1949 1.293e-166 542.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2MSRT@213481|Bdellovibrionales,2WIS7@28221|Deltaproteobacteria 213481|Bdellovibrionales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00333,ko:K13378,ko:K13380 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa,Oxidored_q6 HSJS1_k127_1466559_1 903818.KI912268_gene3055 5.69e-63 222.0 COG0377@1|root,COG0377@2|Bacteria,3Y475@57723|Acidobacteria 57723|Acidobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 HSJS1_k127_1467399_5 1123024.AUII01000006_gene4634 4.87e-45 189.0 COG3212@1|root,COG3212@2|Bacteria 2|Bacteria T peptidase - - - - - - - - - - - - PepSY HSJS1_k127_1467399_2 861299.J421_2386 2.761e-90 335.0 COG1629@1|root,COG4771@2|Bacteria,1ZU8C@142182|Gemmatimonadetes 2|Bacteria P Carboxypeptidase regulatory-like domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_1467399_7 1163408.UU9_12178 4.811e-17 91.0 COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria,1S6D1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_1467399_6 240015.ACP_1095 6.414e-44 165.0 COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia 204432|Acidobacteriia K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ HSJS1_k127_1467399_3 391037.Sare_3446 2.812e-72 256.0 COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4D97F@85008|Micromonosporales 201174|Actinobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 HSJS1_k127_1467399_9 1382359.JIAL01000001_gene1951 5.189e-07 62.0 COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria,2JJBJ@204432|Acidobacteriia 204432|Acidobacteriia D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - - - - - - - - - - DivIC,FtsL HSJS1_k127_1467399_1 443144.GM21_0502 2.686e-116 400.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales 28221|Deltaproteobacteria M Penicillin-binding protein, dimerisation domain ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PASTA,PBP_dimer,Transpeptidase HSJS1_k127_1467399_0 867903.ThesuDRAFT_01664 6.384e-120 408.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis 186801|Clostridia M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M HSJS1_k127_1467399_4 867903.ThesuDRAFT_01663 6.259e-49 186.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WCHQ@538999|Clostridiales incertae sedis 186801|Clostridia M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M HSJS1_k127_1472047_0 314230.DSM3645_22234 1.242e-85 295.0 COG0639@1|root,COG0639@2|Bacteria,2J22W@203682|Planctomycetes 203682|Planctomycetes T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 HSJS1_k127_1472047_1 1131269.AQVV01000020_gene2210 9.464e-77 267.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM HSJS1_k127_1472047_2 370438.PTH_0129 1.407e-16 89.0 COG3222@1|root,COG3222@2|Bacteria,1VANQ@1239|Firmicutes,24GQ0@186801|Clostridia,2630Q@186807|Peptococcaceae 186801|Clostridia S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 HSJS1_k127_1472685_2 304371.MCP_0432 3.678e-34 139.0 COG0433@1|root,arCOG09167@1|root,arCOG00280@2157|Archaea,arCOG00286@2157|Archaea,arCOG09167@2157|Archaea 2157|Archaea P protein kinase activity - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 HSJS1_k127_1472685_1 313628.LNTAR_22015 7.387e-49 185.0 2DM5T@1|root,31U0Y@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126 HSJS1_k127_1472685_0 1267005.KB911259_gene3781 4.27e-63 243.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3N7R3@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF,GGDEF,PAS_3,PAS_4,PAS_9 HSJS1_k127_1472685_3 317619.ANKN01000066_gene2795 2.57e-11 69.0 COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1G21K@1117|Cyanobacteria,1MM6N@1212|Prochloraceae 1117|Cyanobacteria P Na H antiporter nhaP - - - - - - - - - - iJN678.sll0556 Na_H_Exchanger,TrkA_N HSJS1_k127_147345_2 1125863.JAFN01000001_gene1992 1.725e-14 78.0 COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria 28221|Deltaproteobacteria N Putative transposase, YhgA-like - - - - - - - - - - - - DUF4351,Transposase_31 HSJS1_k127_147345_0 448385.sce0381 2.861e-28 125.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_147345_1 234267.Acid_1463 1.508e-23 109.0 2DBYN@1|root,2ZBWH@2|Bacteria,3Y43H@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - HSJS1_k127_1474136_0 1379698.RBG1_1C00001G0780 6.94e-79 273.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B HSJS1_k127_1474136_2 1379698.RBG1_1C00001G0781 1.317e-34 138.0 COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain petA - 1.10.2.2,1.10.9.1 ko:K00411,ko:K02636,ko:K03886 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - iAF987.Gmet_1922 CytB6-F_Fe-S,Rieske,UCR_Fe-S_N HSJS1_k127_1474136_3 472759.Nhal_1087 1.118e-28 127.0 COG0737@1|root,COG0737@2|Bacteria,1RFNB@1224|Proteobacteria 1224|Proteobacteria C oxidation-reduction process - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - - - - - - - - - - Cytochrome_C554 HSJS1_k127_1474136_1 502025.Hoch_5969 7.171e-49 186.0 COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42R7J@68525|delta/epsilon subdivisions,2WMT4@28221|Deltaproteobacteria,2Z0Y2@29|Myxococcales 28221|Deltaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.17.1.4 ko:K13479 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 HSJS1_k127_1480813_1 404589.Anae109_3109 9.678e-13 74.0 2A7EC@1|root,30WBT@2|Bacteria,1PDJ7@1224|Proteobacteria,43E64@68525|delta/epsilon subdivisions,2WZUI@28221|Deltaproteobacteria,2Z2SD@29|Myxococcales 28221|Deltaproteobacteria S Copper binding periplasmic protein CusF - - - - - - - - - - - - CusF_Ec HSJS1_k127_1480813_0 880073.Calab_3717 2.833e-106 362.0 COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria 2|Bacteria H Flavin containing amine oxidoreductase hemG - 1.14.19.9,1.3.3.15,1.3.3.4 ko:K00231,ko:K14266 ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130 M00121,M00789,M00790 R03222,R04178,R09570 RC00885,RC00949 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase HSJS1_k127_1481664_2 331678.Cphamn1_2200 2.317e-11 67.0 COG0629@1|root,COG0629@2|Bacteria,1FE0M@1090|Chlorobi 1090|Chlorobi L PFAM single-strand binding protein Primosomal replication protein n - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB HSJS1_k127_1481664_1 13035.Dacsa_0517 1.948e-12 78.0 COG0697@1|root,COG0697@2|Bacteria,1G24W@1117|Cyanobacteria 1117|Cyanobacteria EG PFAM EamA-like transporter family - - - - - - - - - - - - EamA HSJS1_k127_1481664_0 443143.GM18_0801 8.532e-194 621.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU General secretory system II, protein E domain protein pulE-3 - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N HSJS1_k127_1494274_2 393595.ABO_0106 5.67e-07 61.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XIUV@135619|Oceanospirillales 135619|Oceanospirillales NT chemotaxis protein - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ HSJS1_k127_1494274_3 272630.MexAM1_META1p3037 1.151e-05 53.0 COG0835@1|root,COG0835@2|Bacteria,1N7QA@1224|Proteobacteria,2UIRY@28211|Alphaproteobacteria,1JVR6@119045|Methylobacteriaceae 28211|Alphaproteobacteria NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW HSJS1_k127_1494274_0 309807.SRU_1962 7.122e-207 663.0 COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1FJQN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 HSJS1_k127_1494274_1 1379270.AUXF01000002_gene1596 8.979e-86 302.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X HSJS1_k127_1500803_0 1303518.CCALI_02902 5.005e-32 136.0 COG1131@1|root,COG1131@2|Bacteria 2|Bacteria V ATPase activity ccmA - 3.6.3.41 ko:K01990,ko:K02193 ko02010,map02010 M00254,M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.107 - - ABC_tran HSJS1_k127_1500803_1 448385.sce0381 6.545e-09 67.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1507790_0 240015.ACP_2022 1.103e-226 714.0 COG1048@1|root,COG1048@2|Bacteria,3Y34Q@57723|Acidobacteria,2JHMV@204432|Acidobacteriia 204432|Acidobacteriia C aconitate hydratase - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C HSJS1_k127_1507790_3 90675.XP_010432573.1 2.033e-48 186.0 COG0451@1|root,KOG1502@2759|Eukaryota,37JYY@33090|Viridiplantae,3G71H@35493|Streptophyta,3HP0I@3699|Brassicales 35493|Streptophyta V NmrA-like family - - 1.1.1.354 ko:K15891 ko00900,ko00909,ko01130,map00900,map00909,map01130 - R10412 RC00649 ko00000,ko00001,ko01000 - - - Epimerase HSJS1_k127_1507790_2 381666.H16_A0007 5.335e-58 209.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria 1224|Proteobacteria L Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 HSJS1_k127_1507790_1 861299.J421_3562 1.669e-89 312.0 COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes 2|Bacteria EGP Sugar (and other) transporter - - - ko:K08153 - M00717 - - ko00000,ko00002,ko02000 2.A.1.2.8 - - MFS_1,Sugar_tr HSJS1_k127_1508854_0 203122.Sde_0297 1.903e-32 134.0 COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,1SC1X@1236|Gammaproteobacteria,46CF2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_1508854_1 1122604.JONR01000007_gene2932 2.808e-05 55.0 2EBKV@1|root,335M7@2|Bacteria,1NAHA@1224|Proteobacteria,1SICQ@1236|Gammaproteobacteria,1X6IR@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - zf-HC2 HSJS1_k127_1514847_0 1283300.ATXB01000001_gene1162 2.628e-231 746.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C HSJS1_k127_1514847_1 1049564.TevJSym_bb00010 7.991e-104 345.0 COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Fe-S cluster - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4 HSJS1_k127_1514847_2 1514668.JOOA01000002_gene1882 1.241e-06 61.0 COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,3WIBC@541000|Ruminococcaceae 186801|Clostridia C ferredoxin oxidoreductase porA GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 ko:K00169,ko:K19070 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N HSJS1_k127_1523396_6 196490.AUEZ01000027_gene1723 0.0003295 51.0 COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,2U1FH@28211|Alphaproteobacteria,3K3AB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial membrane protein, YfhO - - - - - - - - - - - - - HSJS1_k127_1523396_0 1444309.JAQG01000100_gene4750 1.831e-129 431.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,26QG6@186822|Paenibacillaceae 91061|Bacilli E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU23070 2-Hacid_dh,2-Hacid_dh_C,ACT HSJS1_k127_1523396_1 479434.Sthe_1990 4.856e-91 316.0 COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia 189775|Thermomicrobia F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N HSJS1_k127_1523396_2 671143.DAMO_0477 6.317e-46 176.0 COG0797@1|root,COG0797@2|Bacteria,2NPV9@2323|unclassified Bacteria 2|Bacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR HSJS1_k127_1523396_4 349521.HCH_05539 1.347e-13 81.0 29VB3@1|root,30GR8@2|Bacteria,1QTAF@1224|Proteobacteria,1SUK5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1523396_3 349521.HCH_05538 5.057e-44 183.0 COG1572@1|root,COG1572@2|Bacteria,1RF0V@1224|Proteobacteria,1SY9C@1236|Gammaproteobacteria,1XNTV@135619|Oceanospirillales 135619|Oceanospirillales S CARDB - - - - - - - - - - - - CARDB,Metallopep,Peptidase_M10 HSJS1_k127_1523396_5 1125863.JAFN01000001_gene1812 9.017e-13 82.0 COG1520@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,1N8Z7@1224|Proteobacteria,43AIY@68525|delta/epsilon subdivisions 1224|Proteobacteria C heme-binding sites - - - - - - - - - - - - PKD,Peptidase_C1 HSJS1_k127_1525199_0 644282.Deba_1140 2.761e-169 554.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD HSJS1_k127_1525199_1 1121468.AUBR01000016_gene2351 4.237e-39 154.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,42GU3@68295|Thermoanaerobacterales 186801|Clostridia M PFAM Lytic transglycosylase catalytic yjbJ - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT HSJS1_k127_1525199_2 903818.KI912268_gene967 4.951e-17 84.0 COG0558@1|root,COG0558@2|Bacteria,3Y520@57723|Acidobacteria 57723|Acidobacteria I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf HSJS1_k127_1530649_1 1249997.JHZW01000002_gene1835 4.069e-38 154.0 COG0421@1|root,COG0421@2|Bacteria 2|Bacteria E spermidine synthase activity speE GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth HSJS1_k127_1530649_0 237368.SCABRO_00534 2.158e-44 169.0 COG3794@1|root,COG3794@2|Bacteria,2J29W@203682|Planctomycetes 2|Bacteria C Polysaccharide lyase family 4, domain II - - - - - - - - - - - - CarboxypepD_reg HSJS1_k127_1531814_1 1242864.D187_006689 1.854e-94 321.0 COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria 1224|Proteobacteria S Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - ko:K06955 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 HSJS1_k127_1531814_2 452637.Oter_1107 3.168e-67 245.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia 74201|Verrucomicrobia K helix_turn_helix, mercury resistance - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 HSJS1_k127_1531814_4 1132441.KI519455_gene3671 3.871e-19 93.0 COG1188@1|root,COG1188@2|Bacteria,2IQ6F@201174|Actinobacteria,1W9M7@1268|Micrococcaceae 201174|Actinobacteria J S4 domain hslR - - ko:K04762 - - - - ko00000,ko03110 - - - S4 HSJS1_k127_1531814_0 1499967.BAYZ01000039_gene2211 2.97e-116 394.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein pqqE GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM HSJS1_k127_1531814_5 203119.Cthe_0232 2.495e-18 100.0 2CEJC@1|root,32R1S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_153241_1 329726.AM1_4991 5.136e-89 304.0 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1G3BJ@1117|Cyanobacteria 1117|Cyanobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N HSJS1_k127_153241_0 251221.35214825 9.826e-90 328.0 COG2755@1|root,COG3055@1|root,COG2755@2|Bacteria,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - 1.1.3.9 ko:K04618 ko00052,map00052 - R01098 RC00194 ko00000,ko00001,ko01000 - - - DUF1929,F5_F8_type_C,Flg_new,Kelch_6,Lipase_GDSL_2 HSJS1_k127_1535750_0 68570.DC74_2696 7.498e-05 54.0 2EW6Z@1|root,33PJY@2|Bacteria,2GK3R@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - HSJS1_k127_1537405_1 269799.Gmet_1215 1.086e-70 256.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43SUG@69541|Desulfuromonadales 28221|Deltaproteobacteria L TIGRFAM DNA polymerase III, alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon HSJS1_k127_1537405_0 269799.Gmet_1578 2.544e-165 552.0 COG0617@1|root,COG0618@1|root,COG3620@1|root,COG0617@2|Bacteria,COG0618@2|Bacteria,COG3620@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,43U0J@69541|Desulfuromonadales 28221|Deltaproteobacteria J CBS domain containing protein ccaA - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd HSJS1_k127_1537405_3 644966.Tmar_0933 6.128e-27 121.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WCMZ@538999|Clostridiales incertae sedis 186801|Clostridia L Conserved hypothetical protein 95 rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 HSJS1_k127_1537405_4 906888.JCM19314_3181 4.503e-14 85.0 COG0526@1|root,COG0526@2|Bacteria,4NS44@976|Bacteroidetes,1I3AY@117743|Flavobacteriia 976|Bacteroidetes CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,DUF3738 HSJS1_k127_1537405_2 1123257.AUFV01000008_gene662 8.679e-60 212.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,1X3SK@135614|Xanthomonadales 135614|Xanthomonadales C Molybdopterin oxidoreductase Fe4S4 domain - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding HSJS1_k127_154237_0 246197.MXAN_2742 4.277e-270 847.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N HSJS1_k127_1543183_0 1385935.N836_16145 2.542e-19 104.0 COG2319@1|root,COG3267@1|root,COG4409@1|root,COG5295@1|root,COG2319@2|Bacteria,COG3267@2|Bacteria,COG4409@2|Bacteria,COG5295@2|Bacteria,1GQM4@1117|Cyanobacteria,1HI3C@1150|Oscillatoriales 1117|Cyanobacteria UW exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - HSJS1_k127_1543183_1 1385517.N800_06960 1.622e-16 89.0 COG3485@1|root,COG3485@2|Bacteria 2|Bacteria Q protocatechuate 3,4-dioxygenase activity - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C HSJS1_k127_1543183_2 156889.Mmc1_1079 9.299e-07 61.0 COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria 1224|Proteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 HSJS1_k127_1545854_0 1123366.TH3_20318 1.939e-16 93.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2JPUZ@204441|Rhodospirillales 204441|Rhodospirillales CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084,ko:K08344 - - - - ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.5 - - DsbC,DsbD,Thioredoxin_7 HSJS1_k127_1545854_1 316067.Geob_1725 2.968e-16 83.0 2DQ41@1|root,334MP@2|Bacteria,1QWJG@1224|Proteobacteria 1224|Proteobacteria S Kazal type serine protease inhibitors - - - - - - - - - - - - Kazal_1 HSJS1_k127_1546631_7 394221.Mmar10_1181 0.0005772 48.0 COG4714@1|root,COG4714@2|Bacteria,1QV7Y@1224|Proteobacteria,2U2GT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 HSJS1_k127_1546631_4 700598.Niako_6317 2.312e-20 100.0 COG1044@1|root,COG1044@2|Bacteria,4NT1C@976|Bacteroidetes,1J18R@117747|Sphingobacteriia 976|Bacteroidetes M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - - - - - - - - - - - HSJS1_k127_1546631_1 766499.C357_12359 4.026e-101 351.0 COG1044@1|root,COG1044@2|Bacteria,1R1TS@1224|Proteobacteria 1224|Proteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - - - - - - - - - - - HSJS1_k127_1546631_2 1123059.KB823013_gene356 1.128e-92 331.0 2DKWY@1|root,30NX3@2|Bacteria,1RBMB@1224|Proteobacteria,2UMF7@28211|Alphaproteobacteria,43ZR3@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1546631_0 518766.Rmar_1316 9.967e-105 349.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1FJIC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Polysaccharide biosynthesis protein galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd HSJS1_k127_1546631_6 930171.Asphe3_38440 2.261e-08 63.0 COG3064@1|root,COG3064@2|Bacteria,2I9Z1@201174|Actinobacteria 201174|Actinobacteria M Membrane - - - - - - - - - - - - Flg_new,Germane HSJS1_k127_1546631_3 1236541.BALL01000005_gene870 1.742e-24 117.0 COG0845@1|root,COG0845@2|Bacteria,1P5GT@1224|Proteobacteria,1S7A6@1236|Gammaproteobacteria,2Q8V8@267890|Shewanellaceae 1236|Gammaproteobacteria M HlyD family secretion protein - - - - - - - - - - - - HlyD_3,HlyD_D23 HSJS1_k127_1546631_5 1236541.BALL01000005_gene871 3.631e-09 67.0 COG0845@1|root,COG0845@2|Bacteria,1R78S@1224|Proteobacteria,1S0GJ@1236|Gammaproteobacteria,2QA9F@267890|Shewanellaceae 1236|Gammaproteobacteria M HlyD family secretion protein - - - ko:K02005 - - - - ko00000 - - - HlyD_3,HlyD_D23 HSJS1_k127_1547310_1 215803.DB30_6706 6.807e-30 126.0 COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2YUBN@29|Myxococcales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM HSJS1_k127_1547310_0 483219.LILAB_02920 9.073e-86 298.0 COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,438D4@68525|delta/epsilon subdivisions,2X3NA@28221|Deltaproteobacteria,2YWMP@29|Myxococcales 28221|Deltaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM HSJS1_k127_1553898_1 311403.Arad_2811 3.544e-27 129.0 COG0438@1|root,COG2520@1|root,COG0438@2|Bacteria,COG2520@2|Bacteria,1RI6Q@1224|Proteobacteria,2UH7F@28211|Alphaproteobacteria,4BKIV@82115|Rhizobiaceae 28211|Alphaproteobacteria M Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 HSJS1_k127_1553898_0 1231190.NA8A_17448 4.014e-101 356.0 COG0438@1|root,COG0438@2|Bacteria,1QY5E@1224|Proteobacteria,2VF92@28211|Alphaproteobacteria,43MAQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4 HSJS1_k127_1584872_0 251221.35211765 3.809e-171 567.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_1584872_1 420246.GTNG_2709 6.559e-98 332.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1WEHU@129337|Geobacillus 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b HSJS1_k127_1590414_4 404380.Gbem_3206 1.733e-53 201.0 COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,43TAA@69541|Desulfuromonadales 28221|Deltaproteobacteria D PFAM PSP1 domain protein - - - - - - - - - - - - PSP1 HSJS1_k127_1590414_0 1121468.AUBR01000017_gene2358 2.722e-136 461.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,42FB3@68295|Thermoanaerobacterales 186801|Clostridia F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N HSJS1_k127_1590414_1 1121920.AUAU01000002_gene2003 1.429e-80 285.0 COG0280@1|root,COG0280@2|Bacteria,3Y6AD@57723|Acidobacteria 57723|Acidobacteria C Phosphate acetyl/butaryl transferase - - 2.3.1.8 ko:K00625 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - PTA_PTB HSJS1_k127_1590414_3 1128421.JAGA01000001_gene2144 7.298e-59 210.0 COG3127@1|root,COG3127@2|Bacteria 2|Bacteria Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_1590414_5 1128421.JAGA01000001_gene2145 1.644e-35 141.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity MA20_05735 - - - - - - - - - - - HTH_34 HSJS1_k127_1590414_2 760568.Desku_2556 1.364e-78 269.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,260D7@186807|Peptococcaceae 186801|Clostridia H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf HSJS1_k127_1591996_0 1254432.SCE1572_33210 4.982e-136 456.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2Z1M7@29|Myxococcales 28221|Deltaproteobacteria L DNA polymerase type-B family polB - 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1,RNase_H_2 HSJS1_k127_1591996_4 1207063.P24_11797 4.597e-30 133.0 COG1652@1|root,COG1652@2|Bacteria 2|Bacteria S positive regulation of growth rate - - - - - - - - - - - - DUF4157 HSJS1_k127_1591996_2 28444.JODQ01000013_gene2933 9.361e-66 230.0 COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria 201174|Actinobacteria S protein conserved in bacteria - - - - - - - - - - - - OmdA HSJS1_k127_1591996_3 523791.Kkor_1006 1.209e-55 217.0 2C7KZ@1|root,32RJE@2|Bacteria,1N3NH@1224|Proteobacteria,1SM9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1591996_1 1161401.ASJA01000012_gene808 2.243e-125 406.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,2UMCM@28211|Alphaproteobacteria,43Z3F@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 HSJS1_k127_1593550_0 234267.Acid_3798 3.647e-147 497.0 COG0577@1|root,COG0577@2|Bacteria 234267.Acid_3798|- V efflux transmembrane transporter activity - - - - - - - - - - - - - HSJS1_k127_1593550_1 338963.Pcar_0596 4.874e-110 372.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,43S0N@69541|Desulfuromonadales 28221|Deltaproteobacteria P Divalent cation transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N HSJS1_k127_1593550_2 479433.Caci_7039 1.358e-15 85.0 COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria 201174|Actinobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N HSJS1_k127_1596310_2 518766.Rmar_2163 1.409e-94 316.0 COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,1FJVN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Malate synthase aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase HSJS1_k127_1596310_1 204669.Acid345_4706 4.051e-188 598.0 COG2224@1|root,COG2224@2|Bacteria,3Y345@57723|Acidobacteria 57723|Acidobacteria C Isocitrate lyase family - - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL HSJS1_k127_1596310_5 83406.HDN1F_22170 3.686e-35 136.0 COG2337@1|root,COG2337@2|Bacteria,1MYU1@1224|Proteobacteria,1SI9D@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Toxic component of a toxin-antitoxin (TA) module - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin HSJS1_k127_1596310_6 56107.Cylst_1979 8.412e-16 79.0 COG0864@1|root,COG0864@2|Bacteria,1G9E4@1117|Cyanobacteria,1HPW8@1161|Nostocales 1117|Cyanobacteria K Transcriptional regulator - - - - - - - - - - - - - HSJS1_k127_1596310_4 1499967.BAYZ01000159_gene534 4.269e-55 204.0 2DBXQ@1|root,2ZBQY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Peptidase_M50B HSJS1_k127_1596310_3 1519464.HY22_13440 1.167e-84 285.0 COG3880@1|root,COG3880@2|Bacteria 2|Bacteria E PFAM UvrB UvrC protein mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR HSJS1_k127_1596310_0 880073.Calab_0311 7.629e-273 869.0 COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S dicluster domain hybA - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molydop_binding HSJS1_k127_1605162_1 335543.Sfum_1623 5.965e-24 110.0 COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria 1224|Proteobacteria O ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_1605162_0 96561.Dole_1626 3.744e-48 180.0 2B6WS@1|root,31ZWK@2|Bacteria,1RCZJ@1224|Proteobacteria,42ZHX@68525|delta/epsilon subdivisions,2WV3Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1605162_2 1267535.KB906767_gene3332 8.015e-10 68.0 2DKN8@1|root,32UFB@2|Bacteria,3Y55I@57723|Acidobacteria,2JJU7@204432|Acidobacteriia 204432|Acidobacteriia S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 HSJS1_k127_1607121_2 105559.Nwat_2382 1.515e-39 156.0 COG1682@1|root,COG1682@2|Bacteria 2|Bacteria GM macromolecule localization tagG - - ko:K09690,ko:K09692 ko02010,map02010 M00250,M00251 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103,3.A.1.104 - - ABC2_membrane HSJS1_k127_1607121_1 247490.KSU1_B0195 5.291e-91 315.0 COG0438@1|root,COG0438@2|Bacteria,2IXRB@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_1607121_0 1499967.BAYZ01000017_gene6221 1.66e-138 456.0 COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria 2|Bacteria M Bacterial sugar transferase wcaJ - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 HSJS1_k127_1608325_0 391625.PPSIR1_13145 1.276e-90 308.0 COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,42RM6@68525|delta/epsilon subdivisions,2WNFG@28221|Deltaproteobacteria,2Z02I@29|Myxococcales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA HSJS1_k127_1608325_1 1254432.SCE1572_05510 1.446e-48 181.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_1608325_2 1198114.AciX9_3506 4.83e-46 174.0 COG3797@1|root,COG3797@2|Bacteria,3Y5RN@57723|Acidobacteria,2JJWX@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 HSJS1_k127_1608325_6 1219035.NT2_11_00370 5.398e-06 59.0 COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,2TW0W@28211|Alphaproteobacteria,2KDTR@204457|Sphingomonadales 204457|Sphingomonadales IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 HSJS1_k127_1608325_3 246197.MXAN_2117 4.616e-31 136.0 2AN3H@1|root,31D15@2|Bacteria,1QA2J@1224|Proteobacteria,43DX5@68525|delta/epsilon subdivisions,2X90A@28221|Deltaproteobacteria,2Z19M@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1608325_4 1123389.ATXJ01000004_gene1205 1.375e-30 123.0 COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O redox protein regulator of disulfide bond formation osmC - - ko:K04063 - - - - ko00000 - - - OsmC HSJS1_k127_1613513_1 589865.DaAHT2_0017 1.316e-131 434.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,2MI83@213118|Desulfobacterales 28221|Deltaproteobacteria S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC HSJS1_k127_1613513_3 204669.Acid345_4703 6.131e-59 209.0 COG2318@1|root,COG2318@2|Bacteria,3Y4AI@57723|Acidobacteria,2JKRK@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF1572) - - - - - - - - - - - - DUF1572 HSJS1_k127_1613513_2 395963.Bind_2603 2.74e-71 273.0 COG0644@1|root,COG0644@2|Bacteria,1N3JT@1224|Proteobacteria 1224|Proteobacteria C FAD binding domain - - - - - - - - - - - - FAD_binding_3 HSJS1_k127_1613513_0 1144275.COCOR_07206 1.001e-180 587.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria 28221|Deltaproteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding HSJS1_k127_1613513_4 886293.Sinac_2245 7.199e-06 51.0 COG0236@1|root,COG0236@2|Bacteria,2J4HV@203682|Planctomycetes 203682|Planctomycetes IQ Phosphopantetheine attachment site - - - ko:K02078 - - - - ko00000,ko00001 - - - - HSJS1_k127_1623503_0 1254432.SCE1572_14255 5.2e-220 691.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,42N8Z@68525|delta/epsilon subdivisions,2WTR2@28221|Deltaproteobacteria,2YU56@29|Myxococcales 28221|Deltaproteobacteria H AbgT putative transporter family abgT - - ko:K12942 - - - - ko00000 - - - ABG_transport HSJS1_k127_1623503_2 926560.KE387023_gene2626 5.169e-65 235.0 COG0122@1|root,COG0122@2|Bacteria,1WMNJ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L endonuclease III - - - - - - - - - - - - HhH-GPD HSJS1_k127_1623503_1 118161.KB235924_gene6533 3.616e-191 635.0 COG0457@1|root,COG2931@1|root,COG0457@2|Bacteria,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,VCBS HSJS1_k127_1623503_3 869210.Marky_0423 4.803e-46 177.0 COG0671@1|root,COG0671@2|Bacteria,1WKBW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I PFAM PAP2 superfamily - - - - - - - - - - - - PAP2 HSJS1_k127_1623503_4 1268635.Loa_02139 2.719e-36 161.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1JDH5@118969|Legionellales 118969|Legionellales NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC HSJS1_k127_1623503_5 395493.BegalDRAFT_3062 9.38e-07 61.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU pilus assembly protein PilW pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW HSJS1_k127_1626447_4 269799.Gmet_1133 3.073e-45 182.0 COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WJFR@28221|Deltaproteobacteria,43UUT@69541|Desulfuromonadales 28221|Deltaproteobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA HSJS1_k127_1626447_0 269799.Gmet_1132 4.205e-119 391.0 28MU7@1|root,2ZB25@2|Bacteria,1QM5F@1224|Proteobacteria,42TV5@68525|delta/epsilon subdivisions,2WQW0@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF4255) - - - - - - - - - - - - DUF4255 HSJS1_k127_1626447_2 269799.Gmet_1130 1.593e-73 256.0 2AAD4@1|root,314QZ@2|Bacteria,1PUJK@1224|Proteobacteria,437DR@68525|delta/epsilon subdivisions,2XA1Q@28221|Deltaproteobacteria,43VSN@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1626447_1 187272.Mlg_1757 3.047e-96 316.0 2DB76@1|root,2Z7JZ@2|Bacteria,1R41X@1224|Proteobacteria,1S1J8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S T4-like virus tail tube protein gp19 - - - - - - - - - - - - Phage_T4_gp19 HSJS1_k127_1626447_3 269799.Gmet_1128 4.135e-49 175.0 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WKMQ@28221|Deltaproteobacteria,43T9S@69541|Desulfuromonadales 28221|Deltaproteobacteria S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C HSJS1_k127_1627033_1 1121104.AQXH01000001_gene1400 4.575e-144 469.0 COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 HSJS1_k127_1627033_5 1047013.AQSP01000138_gene1074 3.133e-18 88.0 COG2337@1|root,COG2337@2|Bacteria 2|Bacteria T Toxic component of a toxin-antitoxin (TA) module mazF5 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin HSJS1_k127_1627033_2 861299.J421_0688 5.206e-58 207.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins rimL - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 HSJS1_k127_1627033_4 926550.CLDAP_28250 1.743e-37 152.0 COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 HSJS1_k127_1627033_0 1123020.AUIE01000002_gene1699 3.784e-164 537.0 COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,1S0VJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria O cysteine protease - - - - - - - - - - - - Peptidase_C1 HSJS1_k127_1627033_3 1123228.AUIH01000038_gene2740 3.448e-41 172.0 COG1361@1|root,COG3291@1|root,COG3656@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG3656@2|Bacteria,1MWIT@1224|Proteobacteria,1S1VQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M PKD domain - - - - - - - - - - - - FlgD_ig,PKD HSJS1_k127_1630062_1 1210884.HG799462_gene9160 1.073e-70 244.0 COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes 203682|Planctomycetes P heavy metal translocating P-type ATPase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase HSJS1_k127_1630062_2 1191523.MROS_0145 2.399e-50 193.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination pagO - - ko:K07790 ko02020,map02020 - - - ko00000,ko00001 2.A.7 - - EamA HSJS1_k127_1630062_0 290397.Adeh_1417 3.774e-261 821.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales 28221|Deltaproteobacteria C Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_1630062_4 204669.Acid345_3033 6.763e-17 91.0 COG2823@1|root,COG2823@2|Bacteria,3Y41W@57723|Acidobacteria,2JHKW@204432|Acidobacteriia 204432|Acidobacteriia S BON domain - - - - - - - - - - - - BON HSJS1_k127_1630062_3 335543.Sfum_0737 1.012e-26 117.0 COG0589@1|root,COG0589@2|Bacteria,1NDJW@1224|Proteobacteria,430KQ@68525|delta/epsilon subdivisions,2WVKY@28221|Deltaproteobacteria,2MRZ2@213462|Syntrophobacterales 28221|Deltaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp HSJS1_k127_1631155_0 1209072.ALBT01000052_gene645 2.554e-148 484.0 28KHV@1|root,2ZA39@2|Bacteria,1RDCS@1224|Proteobacteria,1RYUF@1236|Gammaproteobacteria,1FHYS@10|Cellvibrio 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1631155_1 1123237.Salmuc_02190 1.066e-99 355.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2U19S@28211|Alphaproteobacteria 1224|Proteobacteria Q PFAM Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 HSJS1_k127_1638517_2 1122226.AUHX01000001_gene710 4.855e-81 292.0 COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia 976|Bacteroidetes G LmbE family - - - - - - - - - - - - PIG-L HSJS1_k127_1638517_0 1211814.CAPG01000019_gene619 5.093e-94 319.0 COG1840@1|root,COG1840@2|Bacteria,1TSKP@1239|Firmicutes,4HBH2@91061|Bacilli,1ZDRE@1386|Bacillus 91061|Bacilli P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 HSJS1_k127_1638517_1 1457250.BBMO01000001_gene915 1.334e-85 297.0 COG3839@1|root,arCOG00177@2157|Archaea,2XTFK@28890|Euryarchaeota,23S9H@183963|Halobacteria 183963|Halobacteria E COG3842 ABC-type spermidine putrescine transport systems, ATPase components sfuC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 HSJS1_k127_1638517_3 997346.HMPREF9374_2151 1.881e-25 118.0 COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,27CKY@186824|Thermoactinomycetaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 HSJS1_k127_1640365_0 247490.KSU1_D0507 0.0 1045.0 COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes 203682|Planctomycetes Q Multicopper oxidase - - - - - - - - - - - - - HSJS1_k127_1649820_0 379066.GAU_0341 7.391e-93 321.0 COG0399@1|root,COG0399@2|Bacteria,1ZT81@142182|Gemmatimonadetes 2|Bacteria M DegT/DnrJ/EryC1/StrS aminotransferase family degT - - - - - - - - - - - DegT_DnrJ_EryC1 HSJS1_k127_1649820_1 1121939.L861_13660 2.016e-68 249.0 COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotran_2,Arylsulfotrans HSJS1_k127_1649820_2 1173029.JH980292_gene2839 1.217e-41 154.0 COG3657@1|root,COG3657@2|Bacteria,1G6YT@1117|Cyanobacteria,1HCJV@1150|Oscillatoriales 1117|Cyanobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 HSJS1_k127_1649820_3 1162668.LFE_0136 2.261e-37 143.0 COG3636@1|root,COG3636@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_1652306_3 1192759.AKIB01000028_gene2028 1.621e-22 109.0 COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3386@1|root,COG3391@1|root,COG5276@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2UHRC@28211|Alphaproteobacteria 28211|Alphaproteobacteria FGMQ CARDB - - - - - - - - - - - - CARDB,He_PIG,Laminin_G_3 HSJS1_k127_1652306_0 452637.Oter_1883 9.953e-126 442.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_1652306_1 1499967.BAYZ01000171_gene5600 2.519e-33 136.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 HSJS1_k127_1652306_2 338963.Pcar_1613 1.147e-29 121.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales 28221|Deltaproteobacteria F Carbamoyl-phosphate synthase small chain, CPSase domain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase HSJS1_k127_165913_0 926550.CLDAP_36730 2.943e-142 456.0 COG1960@1|root,COG1960@2|Bacteria,2G5J5@200795|Chloroflexi 200795|Chloroflexi I Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_165913_6 485916.Dtox_1074 2.118e-09 61.0 COG2331@1|root,COG2331@2|Bacteria,1VM29@1239|Firmicutes,24USJ@186801|Clostridia,2638Y@186807|Peptococcaceae 186801|Clostridia S Regulatory protein, FmdB - - - - - - - - - - - - Zn-ribbon_8 HSJS1_k127_165913_2 91604.ID47_04335 1.817e-46 183.0 COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,2UC6S@28211|Alphaproteobacteria,47G6I@766|Rickettsiales 766|Rickettsiales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 HSJS1_k127_165913_5 1242864.D187_002479 1.169e-22 106.0 COG3386@1|root,COG3386@2|Bacteria,1NFEJ@1224|Proteobacteria,43BX0@68525|delta/epsilon subdivisions,2X77S@28221|Deltaproteobacteria,2YVY8@29|Myxococcales 28221|Deltaproteobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - HSJS1_k127_165913_4 1267535.KB906767_gene2521 1.829e-29 131.0 294EW@1|root,2ZRUR@2|Bacteria,3Y5CG@57723|Acidobacteria 57723|Acidobacteria S Protein of unknown function (DUF1569) - - - - - - - - - - - - DUF1569 HSJS1_k127_165913_1 1158760.AQXP01000036_gene2376 4.746e-66 238.0 COG0265@1|root,COG1259@1|root,COG0265@2|Bacteria,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,1S4US@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Bifunctional nuclease - - - - - - - - - - - - DNase-RNase,PDZ_2 HSJS1_k127_165913_3 756272.Plabr_0806 3.513e-38 152.0 COG0303@1|root,COG0303@2|Bacteria,2IXJ1@203682|Planctomycetes 203682|Planctomycetes H Molybdenum cofactor synthesis domain protein moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N HSJS1_k127_1663324_0 521011.Mpal_2068 1.63e-21 111.0 COG3291@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea 2157|Archaea O PFAM PKD domain containing protein - - - - - - - - - - - - CBM_6,NHL,NosD,PKD,SBBP HSJS1_k127_1673885_1 1297742.A176_03031 3.095e-98 328.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787,ko:K15726 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 - - ACR_tran HSJS1_k127_1673885_4 123214.PERMA_0792 3.918e-08 65.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K16079,ko:K22110 - - - - ko00000,ko02000 1.B.35.1,1.B.35.2,1.B.4.2.1 - - MtrB_PioB,OMP_b-brl,OMP_b-brl_2 HSJS1_k127_1673885_2 483219.LILAB_03760 7.229e-80 285.0 COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2Z2R6@29|Myxococcales 28221|Deltaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP HSJS1_k127_1673885_0 1297742.A176_03347 5.341e-154 506.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2YZUC@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HlyD_D23 HSJS1_k127_1673885_3 483219.LILAB_03770 3.122e-34 137.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - iAF987.Gmet_1547 ACR_tran HSJS1_k127_1674499_2 479434.Sthe_2725 6.007e-07 57.0 COG3722@1|root,COG3722@2|Bacteria 2|Bacteria K fumarate hydratase activity - - - - - - - - - - - - DUF4145,MtlR HSJS1_k127_1674499_0 391625.PPSIR1_40340 2.382e-198 635.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YTZ2@29|Myxococcales 28221|Deltaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding HSJS1_k127_1674499_1 932678.THERU_02340 4.019e-28 117.0 COG0635@1|root,COG0635@2|Bacteria,2G4M1@200783|Aquificae 200783|Aquificae H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM HSJS1_k127_1675243_0 237368.SCABRO_02227 3.437e-74 269.0 COG1233@1|root,COG1233@2|Bacteria,2IYK4@203682|Planctomycetes 203682|Planctomycetes C COG1233 Phytoene dehydrogenase and related - - - - - - - - - - - - Amino_oxidase HSJS1_k127_1675243_3 378806.STAUR_2714 6.978e-12 78.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YU8R@29|Myxococcales 28221|Deltaproteobacteria GM GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase HSJS1_k127_1675243_1 502025.Hoch_3215 2.441e-51 202.0 COG0204@1|root,COG0204@2|Bacteria,1N01J@1224|Proteobacteria,42UM7@68525|delta/epsilon subdivisions,2WQN9@28221|Deltaproteobacteria,2Z3CW@29|Myxococcales 28221|Deltaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase HSJS1_k127_1684748_0 397288.C806_04980 0.0001357 50.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3,HTH_31 HSJS1_k127_1684748_1 29306.JOBE01000052_gene6805 0.0006157 52.0 COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator, SARP family - - - - - - - - - - - - BTAD,NB-ARC,TPR_12,Trans_reg_C HSJS1_k127_1693079_0 266117.Rxyl_1929 3.634e-101 335.0 COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria 201174|Actinobacteria O AAA domain - - - - - - - - - - - - AAA_32,Lon_C HSJS1_k127_1693079_2 1122197.ATWI01000009_gene1807 5.899e-17 89.0 COG0589@1|root,COG0589@2|Bacteria,1N31F@1224|Proteobacteria,1S903@1236|Gammaproteobacteria,46BDD@72275|Alteromonadaceae 1236|Gammaproteobacteria T Universal stress protein - - - - - - - - - - - - Usp HSJS1_k127_1693079_1 498761.HM1_1949 2.286e-75 261.0 COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,247Z2@186801|Clostridia 186801|Clostridia H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnC - 1.21.98.1,2.5.1.77 ko:K11779,ko:K11784 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396 RC01381,RC02329,RC03002,RC03007 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM HSJS1_k127_1693608_0 1379270.AUXF01000001_gene2553 0.0 1023.0 COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes 142182|Gemmatimonadetes O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C HSJS1_k127_1693608_1 502025.Hoch_2465 7.803e-88 297.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2YZ69@29|Myxococcales 28221|Deltaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD HSJS1_k127_169940_3 1033802.SSPSH_000621 1.494e-14 75.0 COG0834@1|root,COG0834@2|Bacteria,1NN6F@1224|Proteobacteria,1RZ35@1236|Gammaproteobacteria 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - Lig_chan,SBP_bac_3 HSJS1_k127_169940_2 1116472.MGMO_177c00130 4.491e-20 106.0 28NG6@1|root,2ZBIB@2|Bacteria,1NDWZ@1224|Proteobacteria,1SMF3@1236|Gammaproteobacteria,1XESF@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - HSJS1_k127_169940_1 1268072.PSAB_10140 1.079e-141 456.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,26S2B@186822|Paenibacillaceae 91061|Bacilli C aldo keto reductase yhdN - - ko:K06607,ko:K18471 ko00640,map00640 - R10718 RC00739 ko00000,ko00001,ko01000 - - - Aldo_ket_red HSJS1_k127_169940_0 1242864.D187_008204 6.667e-304 972.0 2C4IS@1|root,2Z81U@2|Bacteria,1MWZ8@1224|Proteobacteria 1224|Proteobacteria S Lantibiotic biosynthesis dehydratase C-term - - - ko:K20483 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - Lant_dehydr_C,Lant_dehydr_N HSJS1_k127_1712774_3 604331.AUHY01000044_gene1792 4.943e-42 156.0 COG1643@1|root,COG1643@2|Bacteria,1WINM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C HSJS1_k127_1712774_4 344747.PM8797T_22263 2.168e-20 97.0 COG0361@1|root,COG0361@2|Bacteria,2J0T1@203682|Planctomycetes 203682|Planctomycetes J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a HSJS1_k127_1712774_1 523791.Kkor_1363 4.792e-91 306.0 COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1S296@1236|Gammaproteobacteria,1XH64@135619|Oceanospirillales 135619|Oceanospirillales L endonuclease - - - - - - - - - - - - Exo_endo_phos HSJS1_k127_1712774_0 378806.STAUR_1666 3.059e-155 505.0 2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function (DUF2891) - - - - - - - - - - - - DUF2891 HSJS1_k127_1712774_2 489825.LYNGBM3L_65450 2.266e-47 175.0 COG3304@1|root,COG3304@2|Bacteria,1G71Z@1117|Cyanobacteria,1HBQP@1150|Oscillatoriales 1117|Cyanobacteria S Inner membrane component domain - - - - - - - - - - - - YccF HSJS1_k127_1712774_5 1121935.AQXX01000142_gene2315 6.15e-19 100.0 COG1240@1|root,COG1240@2|Bacteria,1R4IW@1224|Proteobacteria,1SN40@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - - - - - - - - - - - HSJS1_k127_1717383_0 991905.SL003B_4075 1.506e-122 406.0 COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria 1224|Proteobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_23,HTH_38,HTH_7,rve HSJS1_k127_1717383_1 1123229.AUBC01000040_gene3836 1.845e-97 326.0 COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TS16@28211|Alphaproteobacteria,3JSGF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L IstB-like ATP binding protein - - - - - - - - - - - - IstB_IS21 HSJS1_k127_1725532_4 880073.Calab_0537 1.597e-77 264.0 COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria 2|Bacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 HSJS1_k127_1725532_0 269799.Gmet_1338 4.537e-148 490.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,43TVP@69541|Desulfuromonadales 28221|Deltaproteobacteria GM Polysaccharide biosynthesis protein CapD - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 HSJS1_k127_1725532_11 1395587.P364_0104915 6.156e-05 56.0 COG1216@1|root,COG1216@2|Bacteria,1V01C@1239|Firmicutes,4HEIS@91061|Bacilli,26RPQ@186822|Paenibacillaceae 91061|Bacilli S Uncharacterised nucleotidyltransferase - - - - - - - - - - - - NTP_transf_5 HSJS1_k127_1725532_1 179408.Osc7112_1245 1.361e-146 475.0 COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1H93R@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 HSJS1_k127_1725532_7 1121381.JNIV01000039_gene3837 6.602e-57 216.0 COG0110@1|root,COG0110@2|Bacteria,1WMJK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep HSJS1_k127_1725532_5 706587.Desti_2812 1.079e-68 261.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WN9A@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM sugar transferase - - - - - - - - - - - - Bac_transf HSJS1_k127_1725532_3 682795.AciX8_1498 1.041e-98 352.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups capM - - - - - - - - - - - Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 HSJS1_k127_1725532_9 1242864.D187_002986 2.174e-40 166.0 COG2050@1|root,COG2050@2|Bacteria,1RHAN@1224|Proteobacteria,43157@68525|delta/epsilon subdivisions,2WWIW@28221|Deltaproteobacteria,2YVGQ@29|Myxococcales 28221|Deltaproteobacteria Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 HSJS1_k127_1725532_2 861299.J421_3743 2.801e-124 418.0 COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes 142182|Gemmatimonadetes NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE HSJS1_k127_1725532_10 378806.STAUR_8052 3.287e-09 64.0 2EV1C@1|root,33NGG@2|Bacteria,1NKKY@1224|Proteobacteria,42X6Y@68525|delta/epsilon subdivisions,2WTH7@28221|Deltaproteobacteria,2Z0VE@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1725532_6 671143.DAMO_2141 6.844e-60 215.0 COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria 2|Bacteria S Methyltransferase domain yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 HSJS1_k127_1725532_8 1147.D082_06650 2.465e-53 204.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G0BI@1117|Cyanobacteria,1H4M0@1142|Synechocystis 1117|Cyanobacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_7,TPR_8 HSJS1_k127_1727712_3 1198114.AciX9_2293 4.606e-12 79.0 COG0526@1|root,COG0526@2|Bacteria,3Y7JU@57723|Acidobacteria,2JMWB@204432|Acidobacteriia 204432|Acidobacteriia CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA HSJS1_k127_1727712_0 234267.Acid_1818 8.79e-186 605.0 COG3590@1|root,COG3590@2|Bacteria,3Y31X@57723|Acidobacteria 57723|Acidobacteria O PFAM peptidase M13 - - 3.4.24.71 ko:K01415 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N HSJS1_k127_1727712_1 867903.ThesuDRAFT_02300 8.257e-83 288.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3WCCE@538999|Clostridiales incertae sedis 186801|Clostridia O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 HSJS1_k127_1727712_5 378806.STAUR_7277 1.994e-07 54.0 2ESP3@1|root,33K7K@2|Bacteria,1QAZ4@1224|Proteobacteria,43E4S@68525|delta/epsilon subdivisions,2WZQI@28221|Deltaproteobacteria,2Z2IQ@29|Myxococcales 28221|Deltaproteobacteria S Serine endopeptidase inhibitors - - - - - - - - - - - - Inhibitor_I10 HSJS1_k127_1727712_4 215803.DB30_5688 1.279e-10 63.0 2ESP3@1|root,33K7K@2|Bacteria,1QAZ4@1224|Proteobacteria,43E4S@68525|delta/epsilon subdivisions,2WZQI@28221|Deltaproteobacteria,2Z2IQ@29|Myxococcales 28221|Deltaproteobacteria S Serine endopeptidase inhibitors - - - - - - - - - - - - Inhibitor_I10 HSJS1_k127_1727712_2 448385.sce7175 1.254e-25 113.0 COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,437FT@68525|delta/epsilon subdivisions,2X2ND@28221|Deltaproteobacteria,2YTZD@29|Myxococcales 28221|Deltaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - - HSJS1_k127_1733919_5 1120934.KB894405_gene5372 3.248e-13 83.0 COG1361@1|root,COG1361@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales 201174|Actinobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,DUF3344 HSJS1_k127_1733919_0 945713.IALB_2638 1.234e-199 639.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HSJS1_k127_1733919_2 1294143.H681_07380 8.341e-98 325.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the aspartate glutamate racemases family ygeA GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race HSJS1_k127_1733919_1 983545.Glaag_0826 7.017e-109 392.0 COG2199@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - GAF_2,GGDEF,HTH_8,Sigma54_activat,V4R,XylR_N HSJS1_k127_1733919_3 671143.DAMO_1432 1.911e-57 207.0 COG4636@1|root,COG4636@2|Bacteria,2NRM2@2323|unclassified Bacteria 2|Bacteria S Putative restriction endonuclease - - - - - - - - - - - - Uma2 HSJS1_k127_1736243_1 765869.BDW_10800 3.843e-135 445.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2MT0N@213481|Bdellovibrionales,2WJEN@28221|Deltaproteobacteria 213481|Bdellovibrionales M TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase HSJS1_k127_1736243_0 867845.KI911784_gene896 0.0 1344.0 COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,375DP@32061|Chloroflexia 32061|Chloroflexia F Carbamoyl-phosphate synthetase large chain domain protein carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS HSJS1_k127_1736243_2 1379698.RBG1_1C00001G0110 7.456e-60 211.0 COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria 2|Bacteria F Belongs to the CarA family carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1383 CPSase_sm_chain,GATase HSJS1_k127_1742185_3 448385.sce0381 1.636e-27 126.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1742185_6 118166.JH976537_gene364 3.422e-10 70.0 COG4576@1|root,COG4576@2|Bacteria,1G7WP@1117|Cyanobacteria,1HCHB@1150|Oscillatoriales 1117|Cyanobacteria CQ Carbon dioxide concentrating mechanism carboxysome shell protein ccmL - - ko:K08697 - - - - ko00000 - - - EutN_CcmL HSJS1_k127_1742185_5 502025.Hoch_4425 1.692e-16 85.0 COG4576@1|root,COG4576@2|Bacteria,1Q0YX@1224|Proteobacteria,434YC@68525|delta/epsilon subdivisions,2WZ99@28221|Deltaproteobacteria,2Z1MJ@29|Myxococcales 28221|Deltaproteobacteria CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL HSJS1_k127_1742185_2 1124991.MU9_1050 1.559e-31 131.0 COG4577@1|root,COG4577@2|Bacteria,1R55P@1224|Proteobacteria,1RQTK@1236|Gammaproteobacteria 1236|Gammaproteobacteria CQ propanediol utilization protein pduT - - - - - - - - - - - BMC HSJS1_k127_1742185_0 1499967.BAYZ01000013_gene6421 1.375e-135 446.0 COG1012@1|root,COG1012@2|Bacteria,2NQI9@2323|unclassified Bacteria 2|Bacteria C Aldehyde dehydrogenase family eutE GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 ko:K04021,ko:K13922 ko00620,ko00640,ko01100,ko01120,map00620,map00640,map01100,map01120 - R00228,R09097 RC00004,RC00184,RC01195 ko00000,ko00001,ko01000 - - - Aldedh HSJS1_k127_1742185_4 215803.DB30_1142 9.413e-25 111.0 COG4576@1|root,COG4576@2|Bacteria,1RIK4@1224|Proteobacteria,4362N@68525|delta/epsilon subdivisions,2X9F2@28221|Deltaproteobacteria,2Z246@29|Myxococcales 28221|Deltaproteobacteria CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL HSJS1_k127_1742185_1 215803.DB30_1141 8.612e-39 147.0 COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,42UCN@68525|delta/epsilon subdivisions,2WQ3V@28221|Deltaproteobacteria,2Z195@29|Myxococcales 28221|Deltaproteobacteria CQ BMC - - - ko:K04027 - - - - ko00000 - - - BMC HSJS1_k127_1754804_0 204669.Acid345_3344 2.391e-34 153.0 COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia 204432|Acidobacteriia S PFAM von Willebrand factor type A - - - - - - - - - - - - VWA,VWA_2,VWA_3 HSJS1_k127_1754804_1 1047013.AQSP01000088_gene1632 1.402e-14 88.0 COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NR7I@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - BatD,TPR_16,TPR_2,TPR_6,TPR_8 HSJS1_k127_1755110_3 404589.Anae109_0302 4.512e-68 244.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF208,RNase_HII HSJS1_k127_1755110_6 1123319.AUBE01000027_gene4798 1.511e-30 132.0 COG0119@1|root,COG1853@1|root,COG0119@2|Bacteria,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria 201174|Actinobacteria K PFAM flavin reductase domain protein, FMN-binding - - - - - - - - - - - - Flavin_Reduct,HMGL-like HSJS1_k127_1755110_0 391625.PPSIR1_28606 2.581e-113 393.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,2YUMG@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N HSJS1_k127_1755110_4 426117.M446_0241 8.786e-43 176.0 COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,2U0BX@28211|Alphaproteobacteria,1JSI9@119045|Methylobacteriaceae 28211|Alphaproteobacteria NT PFAM MCP methyltransferase CheR-type - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N HSJS1_k127_1755110_2 404589.Anae109_3532 2.698e-71 253.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria 1224|Proteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheD,Response_reg HSJS1_k127_1755110_1 1278073.MYSTI_03088 2.619e-84 308.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria 28221|Deltaproteobacteria T ATP-binding region ATPase domain protein cheA4 - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,HATPase_c,Hpt,Response_reg HSJS1_k127_1755110_7 1003195.SCAT_2611 3.488e-05 50.0 COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria 201174|Actinobacteria L adenine glycosylase mutY GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD HSJS1_k127_1755110_5 351607.Acel_1872 4.672e-39 159.0 COG0840@1|root,COG0840@2|Bacteria,2IA80@201174|Actinobacteria 201174|Actinobacteria NT chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CHASE3,MCPsignal HSJS1_k127_1756954_0 861299.J421_3954 3.691e-36 150.0 2C0MY@1|root,30KW5@2|Bacteria,1ZTVN@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - HSJS1_k127_1765945_2 335543.Sfum_4007 8.294e-130 445.0 COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria 1224|Proteobacteria S Peptidase family C25 - - - - - - - - - - - - Peptidase_C25 HSJS1_k127_1765945_3 768671.ThimaDRAFT_4869 4.213e-78 274.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - ko:K22227 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM HSJS1_k127_1765945_7 2340.JV46_22710 0.0001198 54.0 2944W@1|root,2ZRJF@2|Bacteria,1P770@1224|Proteobacteria,1SUA7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Coenzyme PQQ synthesis protein D (PqqD) - - - - - - - - - - - - PqqD HSJS1_k127_1765945_5 768671.ThimaDRAFT_4875 2.95e-25 119.0 2DR3D@1|root,339ZZ@2|Bacteria,1QT81@1224|Proteobacteria,1SU5M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1765945_1 926569.ANT_05360 7.655e-135 454.0 COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi 200795|Chloroflexi BK Radical_SAM C-terminal domain - - 2.3.1.48 ko:K07739 - - - - ko00000,ko01000,ko03016,ko03036 - - - Acetyltransf_1,Radical_SAM,Radical_SAM_C HSJS1_k127_1765945_6 1232437.KL661961_gene2948 4.37e-21 102.0 2EG6A@1|root,339Y4@2|Bacteria,1NIH0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF2007 HSJS1_k127_1765945_4 522306.CAP2UW1_0011 1.112e-39 153.0 2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 HSJS1_k127_1765945_0 1121405.dsmv_0043 8.657e-161 523.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales 28221|Deltaproteobacteria S pfam abc-1 - - - ko:K03688 - - - - ko00000 - - - ABC1 HSJS1_k127_1773151_3 1089551.KE386572_gene487 7.394e-59 211.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,4BPWM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C HSJS1_k127_1773151_2 518766.Rmar_1302 1.593e-98 338.0 2DC2B@1|root,2ZCMA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_1773151_0 502025.Hoch_5309 1.76e-258 807.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales 28221|Deltaproteobacteria S ABC transporter yjjK - 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn HSJS1_k127_1773151_5 401053.AciPR4_3655 0.0001126 50.0 COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria,2JI3C@204432|Acidobacteriia 204432|Acidobacteriia V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_1773151_4 390989.JOEG01000009_gene1001 6.363e-16 88.0 COG2227@1|root,COG2227@2|Bacteria,2ID71@201174|Actinobacteria,4D9P6@85008|Micromonosporales 201174|Actinobacteria H Methyltransferase domain ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 HSJS1_k127_1773151_1 1163409.UUA_17005 3.473e-173 566.0 COG2234@1|root,COG2234@2|Bacteria,1MWQ0@1224|Proteobacteria,1S1UU@1236|Gammaproteobacteria,1X439@135614|Xanthomonadales 135614|Xanthomonadales S peptidase - - - - - - - - - - - - Peptidase_M28 HSJS1_k127_1775287_1 861299.J421_3908 2.243e-46 177.0 COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes 142182|Gemmatimonadetes K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_1775287_2 1121456.ATVA01000016_gene1958 2.327e-46 178.0 COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,43BTI@68525|delta/epsilon subdivisions,2X74F@28221|Deltaproteobacteria,2MCV3@213115|Desulfovibrionales 28221|Deltaproteobacteria M Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 HSJS1_k127_1775287_0 1089547.KB913013_gene2262 2.363e-108 372.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 HSJS1_k127_1787805_1 639030.JHVA01000001_gene2645 2.153e-41 156.0 COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia 204432|Acidobacteriia K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR HSJS1_k127_1787805_0 639030.JHVA01000001_gene2611 1.134e-109 383.0 COG0577@1|root,COG0577@2|Bacteria,3Y36E@57723|Acidobacteria,2JHJ3@204432|Acidobacteriia 204432|Acidobacteriia V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_1788113_7 1219626.HMPREF1639_06660 1.801e-05 51.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25QY6@186804|Peptostreptococcaceae 186801|Clostridia J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d HSJS1_k127_1788113_4 1089553.Tph_c13460 2.38e-49 183.0 COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,42GU1@68295|Thermoanaerobacterales 186801|Clostridia S PFAM Appr-1-p processing domain protein ymdB - - - - - - - - - - - Macro HSJS1_k127_1788113_0 1158150.KB906245_gene2098 5.526e-116 387.0 COG1914@1|root,COG1914@2|Bacteria,1MWET@1224|Proteobacteria,1RY2N@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Mn2 and Fe2 transporters of the NRAMP family Z012_09610 - - - - - - - - - - - Nramp HSJS1_k127_1788113_6 926556.Echvi_3199 1.606e-17 87.0 COG0640@1|root,COG0640@2|Bacteria,4NU19@976|Bacteroidetes,47VIY@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 HSJS1_k127_1788113_2 525904.Tter_0760 5.522e-78 268.0 COG2220@1|root,COG2220@2|Bacteria,2NPQC@2323|unclassified Bacteria 2|Bacteria S Belongs to the UPF0173 family - - - - - - - - - - - - Abhydrolase_3,Lactamase_B_2,Lactamase_B_3 HSJS1_k127_1788113_5 379066.GAU_1878 6.395e-48 177.0 COG0290@1|root,COG0290@2|Bacteria,1ZTM6@142182|Gemmatimonadetes 142182|Gemmatimonadetes J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N HSJS1_k127_1788113_1 604331.AUHY01000012_gene2717 2.291e-98 336.0 COG1108@1|root,COG1108@2|Bacteria,1WM8Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P ABC 3 transport family - - - ko:K11709 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3 HSJS1_k127_1788113_3 1237149.C900_05808 1.802e-76 268.0 COG1108@1|root,COG1321@1|root,COG1108@2|Bacteria,COG1321@2|Bacteria,4NH3D@976|Bacteroidetes,47MU3@768503|Cytophagia 976|Bacteroidetes KP ABC 3 transport family mntC - - ko:K11708 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3,Fe_dep_repr_C HSJS1_k127_1791118_0 1232410.KI421413_gene655 2.324e-227 710.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,43UET@69541|Desulfuromonadales 28221|Deltaproteobacteria G Carbohydrate phosphorylase - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase HSJS1_k127_1800228_4 5346.XP_001835791.1 6.492e-07 53.0 COG2930@1|root,KOG1843@2759|Eukaryota,38FCU@33154|Opisthokonta,3NWAM@4751|Fungi,3UXUS@5204|Basidiomycota,22866@155619|Agaricomycetes,3W3BJ@5338|Agaricales 4751|Fungi S Las17-binding protein actin regulator - GO:0001726,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005856,GO:0005886,GO:0005933,GO:0005935,GO:0005938,GO:0006810,GO:0006897,GO:0006996,GO:0007010,GO:0007015,GO:0008092,GO:0008150,GO:0008289,GO:0009987,GO:0015629,GO:0016020,GO:0016043,GO:0016192,GO:0022607,GO:0030029,GO:0030036,GO:0030427,GO:0030479,GO:0030863,GO:0030864,GO:0031252,GO:0031253,GO:0031256,GO:0031344,GO:0032587,GO:0035091,GO:0042995,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0051015,GO:0051017,GO:0051128,GO:0051179,GO:0051234,GO:0051641,GO:0051666,GO:0060491,GO:0061572,GO:0061645,GO:0065007,GO:0071840,GO:0071944,GO:0097435,GO:0098590,GO:0098657,GO:0099568,GO:0120025,GO:0120032,GO:0120035,GO:0120038,GO:1900027 - ko:K20523 - - - - ko00000,ko04131 - - - SH3_1,SH3_2,Ysc84 HSJS1_k127_1800228_1 1519464.HY22_11745 1.352e-36 146.0 COG0457@1|root,COG0457@2|Bacteria 1519464.HY22_11745|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_1800228_3 246197.MXAN_3773 3.775e-07 54.0 COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria 1224|Proteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_1800228_2 1128421.JAGA01000002_gene1598 4.98e-31 141.0 COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria 2|Bacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 HSJS1_k127_1800228_0 909663.KI867151_gene3132 1.207e-92 317.0 COG0774@1|root,COG2204@1|root,COG0774@2|Bacteria,COG2204@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,2MRFZ@213462|Syntrophobacterales 28221|Deltaproteobacteria MT UDP-3-O-acyl N-acetylglycosamine deacetylase lpxC - 3.5.1.108 ko:K02535,ko:K13599 ko00540,ko01100,ko02020,map00540,map01100,map02020 M00060,M00498 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005,ko02022 - - - LpxC HSJS1_k127_1803471_0 1242864.D187_006629 2.179e-19 99.0 COG0760@1|root,COG0760@2|Bacteria,1RKBZ@1224|Proteobacteria,42SAP@68525|delta/epsilon subdivisions,2WPWG@28221|Deltaproteobacteria 28221|Deltaproteobacteria O peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 HSJS1_k127_1803471_1 349124.Hhal_1021 8.975e-10 72.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales 135613|Chromatiales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N HSJS1_k127_1805536_2 945713.IALB_1493 4.313e-32 126.0 2CIU6@1|root,32S8H@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_1805536_0 1121920.AUAU01000006_gene324 1.207e-186 593.0 COG3185@1|root,COG3185@2|Bacteria,3Y2XN@57723|Acidobacteria 57723|Acidobacteria E Acyclic terpene utilisation family protein AtuA - - - - - - - - - - - - AtuA HSJS1_k127_1805536_1 1047013.AQSP01000130_gene1877 9.825e-51 191.0 COG1711@1|root,COG1711@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF3014 HSJS1_k127_1805536_3 700598.Niako_0423 1.968e-27 113.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IPEF@117747|Sphingobacteriia 976|Bacteroidetes I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) accD5 - - - - - - - - - - - Carboxyl_trans HSJS1_k127_1817284_0 1121472.AQWN01000003_gene1462 9.911e-24 116.0 COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,260PT@186807|Peptococcaceae 186801|Clostridia S PFAM peptidase U62 modulator of DNA gyrase - - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD HSJS1_k127_1817284_2 75379.Tint_2690 0.0003059 46.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,1KIWK@119065|unclassified Burkholderiales 28216|Betaproteobacteria S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD HSJS1_k127_1819031_3 926560.KE387026_gene4176 5.772e-40 154.0 COG4585@1|root,COG4585@2|Bacteria,1WMI2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Histidine kinase - - 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HisKA_3 HSJS1_k127_1819031_1 1122223.KB890688_gene1670 1.289e-85 287.0 COG2197@1|root,COG2197@2|Bacteria,1WM1U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T helix_turn_helix, Lux Regulon - - - ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg HSJS1_k127_1819031_2 926569.ANT_16180 4.742e-85 296.0 COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi 200795|Chloroflexi G PFAM PfkB domain protein adoK - 2.7.1.20 ko:K00856 ko00230,ko01100,map00230,map01100 - R00185 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB HSJS1_k127_1819031_4 861299.J421_3015 7.5e-39 158.0 2DG4T@1|root,2ZUHN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_1819031_5 391625.PPSIR1_36924 4.309e-05 55.0 COG1388@1|root,COG3770@1|root,COG1388@2|Bacteria,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,42VK7@68525|delta/epsilon subdivisions,2WS1M@28221|Deltaproteobacteria,2YVMA@29|Myxococcales 28221|Deltaproteobacteria M LysM domain protein mepA - - ko:K07261 - - - - ko00000,ko01000,ko01002,ko01011 - - - LysM,Peptidase_M74 HSJS1_k127_1819031_0 1266908.AQPB01000025_gene2730 1.151e-197 627.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV HSJS1_k127_1828190_1 1122132.AQYH01000002_gene1245 2.462e-84 293.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2TT5I@28211|Alphaproteobacteria,4BCWB@82115|Rhizobiaceae 28211|Alphaproteobacteria I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat HSJS1_k127_1828190_0 946077.W5A_01240 3.232e-89 317.0 COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia 976|Bacteroidetes E asparaginase iaaA - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 HSJS1_k127_1828190_5 1122612.AUBA01000010_gene11 3.879e-05 56.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,2JZY8@204457|Sphingomonadales 204457|Sphingomonadales S peptidase U62, modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD HSJS1_k127_1828190_3 1396141.BATP01000057_gene3021 1.407e-59 220.0 COG2518@1|root,COG2518@2|Bacteria,46V8Z@74201|Verrucomicrobia,2IUUY@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - PCMT HSJS1_k127_1828190_2 1379698.RBG1_1C00001G0062 4.422e-66 247.0 COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT HSJS1_k127_1828190_4 1541065.JRFE01000017_gene26 5.827e-35 136.0 COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3VIYE@52604|Pleurocapsales 1117|Cyanobacteria T COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,Response_reg HSJS1_k127_1829869_0 1267535.KB906767_gene5241 2.131e-213 688.0 COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria 57723|Acidobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest HSJS1_k127_1829869_2 1499967.BAYZ01000008_gene5415 9.855e-47 181.0 COG3551@1|root,COG3551@2|Bacteria 2|Bacteria J Protein conserved in bacteria - - - ko:K07011 - - - - ko00000 - - - Glyco_trans_1_4,Glycos_transf_2,TPR_19 HSJS1_k127_1829869_1 477974.Daud_0639 3.697e-65 235.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae 186801|Clostridia I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C HSJS1_k127_183072_0 1267535.KB906767_gene5244 3.919e-52 201.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase HSJS1_k127_1830967_1 85643.Tmz1t_2186 1.192e-38 163.0 28MTI@1|root,2ZB1Q@2|Bacteria,1R894@1224|Proteobacteria,2VMZB@28216|Betaproteobacteria,2KVD1@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - HSJS1_k127_1830967_0 985054.JQEZ01000012_gene2988 1.892e-211 732.0 COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1N9RU@1224|Proteobacteria,2UMNF@28211|Alphaproteobacteria,4NDN9@97050|Ruegeria 28211|Alphaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - HSJS1_k127_1833681_0 1123242.JH636435_gene2052 1.252e-125 424.0 COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes 203682|Planctomycetes P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger HSJS1_k127_1833681_1 1183438.GKIL_2277 5.824e-18 99.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4440,SnoaL_2,SnoaL_4 HSJS1_k127_1839370_2 1121920.AUAU01000005_gene930 7.215e-26 125.0 COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria 57723|Acidobacteria T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8 HSJS1_k127_1839370_0 448385.sce3597 1.828e-114 390.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales 28221|Deltaproteobacteria T Bacterial regulatory protein, Fis family ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_1839370_3 379066.GAU_2186 7.525e-26 115.0 COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Cold shock protein domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD HSJS1_k127_1839370_1 1122134.KB893650_gene440 2.929e-68 242.0 COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria,1XPQC@135619|Oceanospirillales 135619|Oceanospirillales HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - - HSJS1_k127_1842786_8 1121104.AQXH01000003_gene361 2.095e-26 119.0 COG0428@1|root,COG0428@2|Bacteria 2|Bacteria P transporter - - - - - - - - - - - - Zip HSJS1_k127_1842786_4 861299.J421_1987 8.016e-87 293.0 COG0428@1|root,COG0428@2|Bacteria 2|Bacteria P transporter - - - - - - - - - - - - Zip HSJS1_k127_1842786_5 472759.Nhal_2971 9.824e-86 287.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales 135613|Chromatiales O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA HSJS1_k127_1842786_2 743718.Isova_0153 1.848e-99 355.0 COG4222@1|root,COG4222@2|Bacteria,2GJN8@201174|Actinobacteria,4F3JV@85017|Promicromonosporaceae 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos HSJS1_k127_1842786_3 1089552.KI911559_gene7 1.457e-91 317.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,2TT2Q@28211|Alphaproteobacteria,2JR6G@204441|Rhodospirillales 204441|Rhodospirillales S COG0656 Aldo keto reductases, related to diketogulonate reductase - - 1.1.1.346 ko:K06222 - - - - ko00000,ko01000 - - - Aldo_ket_red HSJS1_k127_1842786_7 237368.SCABRO_02896 1.297e-34 140.0 COG3453@1|root,COG3453@2|Bacteria 2|Bacteria J Protein conserved in bacteria - - - - - - - - - - - - DUF442 HSJS1_k127_1842786_6 580332.Slit_2871 1.461e-63 235.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,44VCX@713636|Nitrosomonadales 28216|Betaproteobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos HSJS1_k127_1842786_1 1121920.AUAU01000004_gene789 3.132e-109 374.0 COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria 57723|Acidobacteria C e3 binding domain - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding HSJS1_k127_1842786_0 357808.RoseRS_3003 8.837e-147 479.0 COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi,374XR@32061|Chloroflexia 32061|Chloroflexia C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim HSJS1_k127_1843205_3 247490.KSU1_B0267 1.858e-09 61.0 COG2010@1|root,COG2010@2|Bacteria,2IXPN@203682|Planctomycetes 203682|Planctomycetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C HSJS1_k127_1843205_2 1049564.TevJSym_ac00580 9.306e-54 199.0 COG2010@1|root,COG2010@2|Bacteria,1R28S@1224|Proteobacteria,1T5JD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 HSJS1_k127_1843205_1 247490.KSU1_B0265 3.477e-60 232.0 COG2010@1|root,COG2010@2|Bacteria,2IZN4@203682|Planctomycetes 203682|Planctomycetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3,EB_dh HSJS1_k127_1843205_0 330214.NIDE0562 1.353e-147 494.0 COG0589@1|root,COG1592@1|root,COG0589@2|Bacteria,COG1592@2|Bacteria 2|Bacteria C Rubrerythrin usp1 - 1.6.3.4 ko:K22405 - - - - ko00000,ko01000 - - - DinB_2,Rubrerythrin,Usp HSJS1_k127_1843205_5 1040989.AWZU01000025_gene6305 1.009e-07 59.0 COG4319@1|root,COG4319@2|Bacteria,1RF3Q@1224|Proteobacteria,2U78H@28211|Alphaproteobacteria,3JZ1D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440 HSJS1_k127_1862570_0 1454004.AW11_01044 2.38e-108 385.0 COG0457@1|root,COG1262@1|root,COG5635@1|root,COG0457@2|Bacteria,COG1262@2|Bacteria,COG5635@2|Bacteria,1N26H@1224|Proteobacteria,2VXP7@28216|Betaproteobacteria 28216|Betaproteobacteria T NACHT domain - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - FGE-sulfatase,NACHT HSJS1_k127_1865407_6 246194.CHY_2293 5.608e-39 150.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,42GIE@68295|Thermoanaerobacterales 186801|Clostridia J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p HSJS1_k127_1865407_2 591001.Acfer_1912 2.361e-58 209.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4H3Z7@909932|Negativicutes 909932|Negativicutes J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C HSJS1_k127_1865407_9 553175.POREN0001_0220 7.246e-12 67.0 COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,2FUJQ@200643|Bacteroidia 976|Bacteroidetes J 50S ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 HSJS1_k127_1865407_5 932678.THERU_01490 1.906e-44 165.0 COG0200@1|root,COG0200@2|Bacteria,2G41V@200783|Aquificae 200783|Aquificae J Binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A HSJS1_k127_1865407_0 1047013.AQSP01000074_gene1894 1.401e-188 599.0 COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria 2|Bacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY HSJS1_k127_1865407_3 710696.Intca_2735 6.222e-47 175.0 COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4FGDU@85021|Intrasporangiaceae 201174|Actinobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid HSJS1_k127_1865407_1 869210.Marky_1704 8.356e-88 298.0 COG0024@1|root,COG0024@2|Bacteria,1WI2V@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 HSJS1_k127_1865407_8 694431.DESACE_01960 9.566e-14 70.0 COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2M7HN@213113|Desulfurellales 28221|Deltaproteobacteria J Ribosomal protein L36 rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 HSJS1_k127_1865407_4 926566.Terro_3698 4.494e-46 169.0 COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria,2JJAF@204432|Acidobacteriia 204432|Acidobacteriia J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 HSJS1_k127_1865407_7 204669.Acid345_1252 3.245e-38 146.0 COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia 204432|Acidobacteriia J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 HSJS1_k127_1875659_3 1047013.AQSP01000132_gene1707 1.049e-46 193.0 COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria 2|Bacteria GM ATPases associated with a variety of cellular activities rfbB - 3.6.3.38,3.6.3.40 ko:K01990,ko:K09689,ko:K09691,ko:K09693 ko02010,map02010 M00249,M00250,M00251,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103,3.A.1.104 - - ABC_tran,Wzt_C HSJS1_k127_1875659_2 562970.Btus_0876 5.391e-51 190.0 COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,4I47R@91061|Bacilli,279PC@186823|Alicyclobacillaceae 91061|Bacilli P PFAM ABC-2 type transporter - - - ko:K09690 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC2_membrane HSJS1_k127_1875659_4 1265505.ATUG01000001_gene4710 5.991e-32 140.0 COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MKR7@213118|Desulfobacterales 28221|Deltaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 HSJS1_k127_1875659_0 1142394.PSMK_02180 3.016e-124 412.0 COG1899@1|root,COG1899@2|Bacteria,2IWZ8@203682|Planctomycetes 203682|Planctomycetes O COG1899 Deoxyhypusine synthase - - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS HSJS1_k127_1875659_1 493475.GARC_2930 2.416e-104 361.0 COG1228@1|root,COG1228@2|Bacteria,1RCA0@1224|Proteobacteria,1S08B@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1,CIA30 HSJS1_k127_1875659_6 1370125.AUWT01000057_gene1157 2.613e-08 56.0 COG1233@1|root,COG1233@2|Bacteria,2I5XE@201174|Actinobacteria,237P5@1762|Mycobacteriaceae 201174|Actinobacteria Q amine oxidase - - - - - - - - - - - - Amino_oxidase HSJS1_k127_1880773_4 1131462.DCF50_p372 7.441e-09 63.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae 186801|Clostridia S Domain of unknown function (DUF4115) - - - - - - - - - - - - DUF4115,HTH_25 HSJS1_k127_1880773_3 1254432.SCE1572_00345 1.867e-11 75.0 2EI76@1|root,33BYI@2|Bacteria,1RBW7@1224|Proteobacteria,42QZD@68525|delta/epsilon subdivisions,2WN6J@28221|Deltaproteobacteria,2YXMN@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1880773_5 40571.JOEA01000001_gene5052 4.259e-08 63.0 COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4DZJH@85010|Pseudonocardiales 201174|Actinobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG HSJS1_k127_1880773_1 398767.Glov_1588 8.371e-60 215.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria 28221|Deltaproteobacteria T protein phosphatase 2C domain protein - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 HSJS1_k127_1880773_2 278963.ATWD01000001_gene1886 4.196e-22 110.0 COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia 204432|Acidobacteriia S TIGRFAM VWFA-related Acidobacterial domain - - - - - - - - - - - - - HSJS1_k127_1880773_0 1232410.KI421421_gene3543 6.642e-137 440.0 COG2820@1|root,COG2820@2|Bacteria,1QVR4@1224|Proteobacteria,42N9X@68525|delta/epsilon subdivisions,2WJ8F@28221|Deltaproteobacteria,43S8P@69541|Desulfuromonadales 28221|Deltaproteobacteria F Phosphorylase superfamily - - 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - PNP_UDP_1 HSJS1_k127_1882620_0 518766.Rmar_2091 1.251e-157 509.0 COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes 976|Bacteroidetes E TIGRFAM amidase, hydantoinase carbamoylase family - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 HSJS1_k127_1882620_3 391612.CY0110_01425 6.212e-05 48.0 2EH9Q@1|root,33B1J@2|Bacteria,1GAX5@1117|Cyanobacteria,3KIS1@43988|Cyanothece 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_1882620_1 1121920.AUAU01000006_gene330 1.945e-102 349.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria 57723|Acidobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase HSJS1_k127_1884046_1 1265313.HRUBRA_00108 1.956e-113 371.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,1J5WK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EU COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 HSJS1_k127_1884046_3 386456.JQKN01000014_gene3102 4.323e-08 62.0 COG1913@1|root,arCOG00458@2157|Archaea,2XSVV@28890|Euryarchaeota 28890|Euryarchaeota S zinc metalloprotease whose natural substrate is amzA GO:0003674,GO:0003824,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0071704,GO:0140096,GO:1901564 - ko:K06974 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M54 HSJS1_k127_1884046_4 396588.Tgr7_0866 1.159e-06 62.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding - - - ko:K06149 - - - - ko00000 - - - Usp HSJS1_k127_1884046_0 1121920.AUAU01000021_gene2509 2.242e-198 631.0 COG0674@1|root,COG0674@2|Bacteria,3Y3NB@57723|Acidobacteria 57723|Acidobacteria C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.7 ko:K00186 ko00280,ko01100,map00280,map01100 - R07160,R08566,R08567 RC00004,RC02833,RC02856 br01601,ko00000,ko00001,ko01000 - - - PFOR_II,POR_N HSJS1_k127_1884046_2 1121920.AUAU01000021_gene2510 1.266e-45 166.0 COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,3Y3G3@57723|Acidobacteria 57723|Acidobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.7 ko:K00187 ko00280,ko01100,map00280,map01100 - R07160,R08566,R08567 RC00004,RC02833,RC02856 br01601,ko00000,ko00001,ko01000 - - - POR,TPP_enzyme_C HSJS1_k127_1885178_0 316274.Haur_1203 9.867e-112 370.0 COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi 200795|Chloroflexi C 3-hydroxyacyl-CoA dehydrogenase domain protein - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N HSJS1_k127_1885178_1 706587.Desti_2996 8.699e-24 106.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria,2MS7M@213462|Syntrophobacterales 28221|Deltaproteobacteria S Threonylcarbamoyl adenosine biosynthesis protein TsaE yjeE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE HSJS1_k127_1885178_2 1232436.CAPF01000018_gene443 4.703e-21 98.0 COG0212@1|root,COG0212@2|Bacteria,2HTSA@201174|Actinobacteria,4CW6U@84998|Coriobacteriia 84998|Coriobacteriia H 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig HSJS1_k127_1885658_0 926550.CLDAP_18550 8.255e-204 649.0 COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi 200795|Chloroflexi F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade - 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 HSJS1_k127_1885658_1 1089550.ATTH01000001_gene1831 1.249e-174 583.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_1890618_0 1232410.KI421416_gene2596 2.877e-97 327.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales 28221|Deltaproteobacteria NU General secretory system II, protein E domain protein pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N,cNMP_binding HSJS1_k127_1890618_2 240015.ACP_1606 1.134e-47 184.0 COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria,2JIYJ@204432|Acidobacteriia 204432|Acidobacteriia M PFAM glycosyl transferase family 9 - - - ko:K02841 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 HSJS1_k127_1890618_3 1464048.JNZS01000013_gene3262 1.753e-43 164.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2GKU1@201174|Actinobacteria,4DCN1@85008|Micromonosporales 201174|Actinobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - - - - - - - - - - - CTP_transf_like,PfkB HSJS1_k127_1890618_1 401526.TcarDRAFT_1319 2.813e-62 227.0 COG2870@1|root,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,4H1UR@909932|Negativicutes 909932|Negativicutes M Bifunctional protein rfaE - - - - - - - - - - - CTP_transf_like,PfkB HSJS1_k127_1896407_0 766499.C357_12359 2.881e-108 360.0 COG1044@1|root,COG1044@2|Bacteria,1R1TS@1224|Proteobacteria 1224|Proteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - - - - - - - - - - - HSJS1_k127_1896407_1 330084.JNYZ01000004_gene540 0.0008554 47.0 COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EARD@85010|Pseudonocardiales 201174|Actinobacteria P Sulfatase - - - - - - - - - - - - Sulfatase HSJS1_k127_1900577_2 247634.GPB2148_1942 1.502e-32 134.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria,1JAKJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin HSJS1_k127_1900577_0 1267533.KB906736_gene989 1.26e-86 324.0 COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria,2JIG6@204432|Acidobacteriia 204432|Acidobacteriia F SAICAR synthetase purC - 6.3.2.6,6.3.4.13 ko:K01923,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt HSJS1_k127_1900577_1 357808.RoseRS_0699 1.778e-86 301.0 COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi,37528@32061|Chloroflexia 32061|Chloroflexia E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N HSJS1_k127_1903437_2 1278073.MYSTI_06352 4.048e-34 150.0 COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales 28221|Deltaproteobacteria NU Tetratricopeptide repeats - - - - - - - - - - - - TPR_11,TPR_16,TPR_19 HSJS1_k127_1903437_0 1385510.N781_12315 1.533e-46 171.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,2YAG5@289201|Pontibacillus 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 HSJS1_k127_1903437_1 243164.DET0339 1.669e-46 171.0 COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi,34CK3@301297|Dehalococcoidia 301297|Dehalococcoidia J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT HSJS1_k127_1904081_3 573370.DMR_04920 8.046e-25 107.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2M81M@213115|Desulfovibrionales 28221|Deltaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b HSJS1_k127_1904081_4 349519.LCK_00137 0.0001952 52.0 COG1396@1|root,COG1396@2|Bacteria,1W07P@1239|Firmicutes,4HYIS@91061|Bacilli,4AXXP@81850|Leuconostocaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 HSJS1_k127_1904081_2 446470.Snas_2253 1.243e-27 124.0 COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria 201174|Actinobacteria I Phospholipid N-methyltransferase - - - - - - - - - - - - Methyltransf_25,RrnaAD HSJS1_k127_1904081_0 1232410.KI421424_gene1752 3.016e-117 419.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,43S51@69541|Desulfuromonadales 28221|Deltaproteobacteria M Mechanosensitive ion channel mscS-2 - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - MS_channel HSJS1_k127_1904081_1 935863.AWZR01000005_gene2238 3.553e-76 269.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RT11@1236|Gammaproteobacteria,1XCXH@135614|Xanthomonadales 135614|Xanthomonadales EU X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - PD40,Peptidase_S9 HSJS1_k127_1907181_0 1254432.SCE1572_33175 1.994e-179 573.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales 28221|Deltaproteobacteria S ABC transporter, ATP-binding protein ybiT - - - - - - - - - - - ABC_tran,ABC_tran_Xtn HSJS1_k127_1907181_1 1410674.JNKU01000002_gene2380 1.325e-26 114.0 COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli 91061|Bacilli J 30S ribosomal protein S12 methylthiotransferase yqeV GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 HSJS1_k127_1927616_1 1307759.JOMJ01000003_gene517 2.786e-61 220.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2M8CF@213115|Desulfovibrionales 28221|Deltaproteobacteria O heat shock protein DnaJ domain protein cbpA - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C HSJS1_k127_1927616_0 335543.Sfum_0263 9.018e-228 712.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MQ8A@213462|Syntrophobacterales 28221|Deltaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N HSJS1_k127_194156_0 234267.Acid_7689 3.861e-122 407.0 COG1131@1|root,COG1131@2|Bacteria,3Y6U6@57723|Acidobacteria 57723|Acidobacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_194156_1 234267.Acid_7690 1.259e-120 428.0 COG3712@1|root,COG3712@2|Bacteria,3Y772@57723|Acidobacteria 57723|Acidobacteria PT FecR protein - - - - - - - - - - - - FecR HSJS1_k127_194156_3 234267.Acid_7691 3.198e-41 160.0 COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria 57723|Acidobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_194156_4 870187.Thini_2240 1.807e-40 160.0 COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,1SAJG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase vapC - - ko:K07062 - - - - ko00000,ko01000,ko02048 - - - PIN HSJS1_k127_194156_5 349124.Hhal_0791 9.335e-20 91.0 COG4691@1|root,COG4691@2|Bacteria 2|Bacteria S Plasmid stability protein - - - ko:K21495 - - - - ko00000,ko02048 - - - Arc HSJS1_k127_194156_2 1278073.MYSTI_04943 5.601e-57 206.0 COG0596@1|root,COG0596@2|Bacteria,1R4N4@1224|Proteobacteria,434SV@68525|delta/epsilon subdivisions,2WZ3Y@28221|Deltaproteobacteria,2Z19T@29|Myxococcales 28221|Deltaproteobacteria S Hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 HSJS1_k127_1944845_0 880073.Calab_2972 5.548e-241 774.0 COG4774@1|root,COG4774@2|Bacteria 2|Bacteria P siderophore transport - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec HSJS1_k127_1946459_1 1120965.AUBV01000001_gene3457 2.662e-51 196.0 COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia 976|Bacteroidetes S RelA SpoT domain protein - - - - - - - - - - - - GTA_TIM HSJS1_k127_1946459_0 886293.Sinac_7018 5.385e-211 677.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IYBE@203682|Planctomycetes 203682|Planctomycetes EU Peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - Peptidase_S9 HSJS1_k127_1946748_0 234267.Acid_6465 9.302e-183 588.0 COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria 57723|Acidobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug HSJS1_k127_1946748_1 47763.JNZA01000007_gene4872 7.656e-07 60.0 COG0500@1|root,COG2226@2|Bacteria,2GQ6J@201174|Actinobacteria 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 HSJS1_k127_195408_0 639282.DEFDS_1228 7.121e-183 579.0 COG4799@1|root,COG4799@2|Bacteria,2GEP0@200930|Deferribacteres 200930|Deferribacteres I Carboxyl transferase domain - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans HSJS1_k127_195408_1 639282.DEFDS_0485 4.705e-165 539.0 COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres 200930|Deferribacteres E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT HSJS1_k127_195740_0 1267535.KB906767_gene4651 2.546e-204 663.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_195740_1 1089550.ATTH01000002_gene18 1.161e-06 61.0 COG1470@1|root,COG4733@1|root,COG1470@2|Bacteria,COG4733@2|Bacteria,4PHV3@976|Bacteroidetes,1FK10@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Fibronectin type 3 domain - - - - - - - - - - - - - HSJS1_k127_1968673_1 439235.Dalk_3088 2.943e-23 104.0 2E6X2@1|root,331GI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_1968673_2 1125863.JAFN01000001_gene3582 1.161e-11 77.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE HSJS1_k127_1968673_0 324602.Caur_3337 1.157e-109 365.0 COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi,374T6@32061|Chloroflexia 200795|Chloroflexi F PFAM adenosine AMP deaminase - - 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase HSJS1_k127_1972438_2 1125863.JAFN01000001_gene2149 3.458e-59 214.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM Rhomboid family - - - ko:K07059 - - - - ko00000 - - - DnaJ_C,Rhomboid HSJS1_k127_1972438_5 1122223.KB890696_gene404 6.129e-06 59.0 COG1408@1|root,COG1408@2|Bacteria,1WJWG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Calcineurin-like phosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 HSJS1_k127_1972438_4 871968.DESME_02355 9.726e-12 78.0 COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,260P0@186807|Peptococcaceae 186801|Clostridia S PFAM Calcineurin-like phosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos HSJS1_k127_1972438_1 83406.HDN1F_36380 6.337e-84 287.0 COG0596@1|root,COG0596@2|Bacteria,1QVQK@1224|Proteobacteria,1RZ4K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - ko:K22318 - - - - ko00000 - - - Abhydrolase_1 HSJS1_k127_1972438_3 945713.IALB_0020 7.402e-40 156.0 COG4747@1|root,COG4747@2|Bacteria 2|Bacteria - - hom - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 ko:K00003,ko:K00058,ko:K01754,ko:K04517,ko:K04767 ko00260,ko00270,ko00290,ko00300,ko00400,ko00401,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00400,map00401,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00025,M00570 R00220,R00996,R01513,R01728,R01773,R01775 RC00031,RC00087,RC00125,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3 HSJS1_k127_1972438_0 710696.Intca_3534 4.584e-85 290.0 COG2403@1|root,COG2403@2|Bacteria,2IF9H@201174|Actinobacteria,4FEFF@85021|Intrasporangiaceae 201174|Actinobacteria S cyclic 2,3-diphosphoglycerate synthetase activity - - - - - - - - - - - - - HSJS1_k127_1972453_3 1267535.KB906767_gene2937 9.512e-19 95.0 2FBCE@1|root,343I9@2|Bacteria,3Y8Q4@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - HSJS1_k127_1972453_1 234267.Acid_2952 1.325e-33 139.0 COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria 57723|Acidobacteria M PFAM peptidase C60, sortase A and B - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase HSJS1_k127_1972453_0 338966.Ppro_3482 1.736e-52 209.0 COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,43V5U@69541|Desulfuromonadales 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9 HSJS1_k127_1972453_2 1382306.JNIM01000001_gene1045 1.726e-28 117.0 COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi 200795|Chloroflexi K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg HSJS1_k127_1982228_0 861299.J421_1529 4.062e-32 144.0 COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes 142182|Gemmatimonadetes K sigma factor activity - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - - HSJS1_k127_1987971_1 761193.Runsl_3059 6.494e-35 134.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia 976|Bacteroidetes C Dehydrogenase E1 component pdhB - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C HSJS1_k127_1987971_0 518766.Rmar_1948 2.775e-190 605.0 COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1FJ19@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Beta-eliminating lyase tnaA - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase HSJS1_k127_1987971_2 1121091.AUMP01000054_gene3367 8.404e-10 63.0 2DREZ@1|root,33BFB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_1992083_1 1385515.N791_05085 5.085e-111 373.0 COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,1RNBM@1236|Gammaproteobacteria,1X4IC@135614|Xanthomonadales 135614|Xanthomonadales M mechanosensitive ion channel - - - ko:K16053 - - - - ko00000,ko02000 1.A.23.4.5 - - MS_channel HSJS1_k127_1992083_0 382464.ABSI01000020_gene125 8.752e-162 537.0 COG0471@1|root,COG0471@2|Bacteria,46UA9@74201|Verrucomicrobia,2ITKW@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Citrate transporter - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C HSJS1_k127_1992083_2 313612.L8106_16039 1.207e-70 264.0 COG4249@1|root,COG4249@2|Bacteria,1G42B@1117|Cyanobacteria,1H7VS@1150|Oscillatoriales 1117|Cyanobacteria S Caspase domain - - - - - - - - - - - - Peptidase_C14 HSJS1_k127_1992083_4 1123354.AUDR01000020_gene1992 1.008e-17 91.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,1KRJZ@119069|Hydrogenophilales 119069|Hydrogenophilales K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_1992083_3 472759.Nhal_3138 1.366e-55 208.0 2DBMF@1|root,2Z9YG@2|Bacteria,1NUI3@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_1996217_6 1385515.N791_12615 7.049e-21 104.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria,1X377@135614|Xanthomonadales 135614|Xanthomonadales I desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase HSJS1_k127_1996217_3 756067.MicvaDRAFT_4922 7.931e-51 199.0 COG0500@1|root,COG0500@2|Bacteria,1G1YB@1117|Cyanobacteria,1HA07@1150|Oscillatoriales 1117|Cyanobacteria Q Cyclopropane fatty acid synthase and related methyltransferases - - - - - - - - - - - - Methyltransf_23 HSJS1_k127_1996217_11 266117.Rxyl_0667 0.0006896 53.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria 201174|Actinobacteria O Peptidase s1 and s6 chymotrypsin hap - - - - - - - - - - - - PDZ_2,Trypsin_2 HSJS1_k127_1996217_4 1267533.KB906740_gene318 1.727e-36 160.0 COG0265@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia 204432|Acidobacteriia KT Sigma factor PP2C-like phosphatases - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_3,SpoIIE HSJS1_k127_1996217_7 1089550.ATTH01000002_gene52 7.411e-15 87.0 COG0457@1|root,COG4319@1|root,COG0457@2|Bacteria,COG4319@2|Bacteria 2|Bacteria S peptidyl-tyrosine sulfation - - - - - - - - - - - - Beta-lactamase,DUF4440,SnoaL_2,SnoaL_3 HSJS1_k127_1996217_2 485913.Krac_2433 2.277e-60 221.0 COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi 200795|Chloroflexi C 2Fe-2S -binding domain protein - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 HSJS1_k127_1996217_10 1454007.JAUG01000055_gene3325 2.306e-05 58.0 COG2373@1|root,COG3209@1|root,COG4547@1|root,COG5384@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,COG4547@2|Bacteria,COG5384@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia 976|Bacteroidetes M conserved repeat domain protein - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,SprB HSJS1_k127_1996217_9 1200792.AKYF01000020_gene5246 7.659e-06 60.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,26V17@186822|Paenibacillaceae 91061|Bacilli S Putative glutamine amidotransferase - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 HSJS1_k127_1996217_0 1137268.AZXF01000031_gene950 2.772e-165 534.0 COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4EI3R@85012|Streptosporangiales 201174|Actinobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N HSJS1_k127_1996217_5 203124.Tery_1495 2.125e-36 145.0 COG4627@1|root,COG4627@2|Bacteria,1G9YZ@1117|Cyanobacteria,1HHMI@1150|Oscillatoriales 1117|Cyanobacteria S Pfam Methyltransferase - - - - - - - - - - - - - HSJS1_k127_1997793_0 483219.LILAB_03770 0.0 1292.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - iAF987.Gmet_1547 ACR_tran HSJS1_k127_1997793_1 1267535.KB906767_gene1983 1.748e-69 238.0 COG0798@1|root,COG0798@2|Bacteria,3Y69M@57723|Acidobacteria,2JP2H@204432|Acidobacteriia 57723|Acidobacteria P Sodium Bile acid symporter family - - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF HSJS1_k127_199794_3 1242864.D187_004603 1.958e-23 106.0 COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2YVKR@29|Myxococcales 28221|Deltaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB HSJS1_k127_199794_4 204669.Acid345_2357 9.485e-22 105.0 COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria,2JJKB@204432|Acidobacteriia 204432|Acidobacteriia M Lipopolysaccharide-assembly - - - - - - - - - - - - LptE HSJS1_k127_199794_5 391625.PPSIR1_09855 1.468e-16 83.0 COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2YW1W@29|Myxococcales 28221|Deltaproteobacteria J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p HSJS1_k127_199794_2 330214.NIDE3357 1.484e-25 118.0 COG1729@1|root,COG1729@2|Bacteria,3J0RE@40117|Nitrospirae 40117|Nitrospirae S Outer membrane lipoprotein - - - - - - - - - - - - TPR_6 HSJS1_k127_199794_1 290315.Clim_0748 1.526e-35 142.0 COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi 1090|Chlorobi M PFAM OmpA MotB domain protein - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA HSJS1_k127_199794_0 243231.GSU0025 5.975e-81 283.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,43UDK@69541|Desulfuromonadales 28221|Deltaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N HSJS1_k127_2006650_6 324602.Caur_0990 2.466e-09 61.0 COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi,37574@32061|Chloroflexia 32061|Chloroflexia F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase HSJS1_k127_2006650_1 1267535.KB906767_gene3449 3.257e-112 390.0 COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia 204432|Acidobacteriia G Bacterial fructose-1,6-bisphosphatase, glpX-encoded - - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX HSJS1_k127_2006650_0 1382359.JIAL01000001_gene1344 3.091e-180 573.0 COG1960@1|root,COG1960@2|Bacteria,3Y2FM@57723|Acidobacteria,2JIVG@204432|Acidobacteriia 204432|Acidobacteriia I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_2006650_7 1382356.JQMP01000003_gene2143 7.156e-07 60.0 COG1266@1|root,COG1266@2|Bacteria,2G9FI@200795|Chloroflexi,27YGJ@189775|Thermomicrobia 189775|Thermomicrobia S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi HSJS1_k127_2006650_5 240015.ACP_2974 1.234e-24 109.0 COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria,2JJGJ@204432|Acidobacteriia 204432|Acidobacteriia T Histidine kinase-like ATPase domain - - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 HSJS1_k127_2006650_3 378806.STAUR_7589 5.464e-36 141.0 COG1366@1|root,COG1366@2|Bacteria,1NJGJ@1224|Proteobacteria 1224|Proteobacteria T STAS domain - - - - - - - - - - - - STAS HSJS1_k127_2006650_2 1278073.MYSTI_07697 1.902e-65 235.0 2C36Y@1|root,331F9@2|Bacteria,1P3S7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2006650_8 309799.DICTH_0974 0.0001254 53.0 COG0793@1|root,COG0793@2|Bacteria 2|Bacteria M Belongs to the peptidase S41A family ctpA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 HSJS1_k127_201098_0 1047013.AQSP01000067_gene2201 2.081e-166 547.0 COG3379@1|root,COG3379@2|Bacteria,2NQIG@2323|unclassified Bacteria 2|Bacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest HSJS1_k127_201098_1 234267.Acid_6181 5.608e-26 110.0 COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria 57723|Acidobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest HSJS1_k127_2012196_0 1120965.AUBV01000001_gene3486 1.525e-145 482.0 COG2866@1|root,COG2866@2|Bacteria,4NGIE@976|Bacteroidetes,47N2M@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 HSJS1_k127_2012196_5 1267535.KB906767_gene4523 6.488e-20 106.0 COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria,2JKG4@204432|Acidobacteriia 204432|Acidobacteriia S oxidoreductase activity - - - - - - - - - - - - - HSJS1_k127_2012196_7 1267534.KB906758_gene2525 5.447e-12 80.0 COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria,2JKG4@204432|Acidobacteriia 204432|Acidobacteriia S oxidoreductase activity - - - - - - - - - - - - - HSJS1_k127_2012196_8 525904.Tter_0083 2.458e-06 61.0 COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2NPK1@2323|unclassified Bacteria 2|Bacteria T Tetratricopeptide repeat - - - - - - - - - - - - HEAT_2,NACHT,SIR2_2,TPR_1,TPR_11,TPR_2,TPR_8 HSJS1_k127_2012196_6 204669.Acid345_2506 5.16e-18 97.0 COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia 204432|Acidobacteriia S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 HSJS1_k127_2012196_3 1125863.JAFN01000001_gene566 1.549e-62 233.0 COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WKQH@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q ABC-type transport system involved in resistance to organic solvents periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD HSJS1_k127_2012196_2 1278073.MYSTI_04217 7.713e-69 255.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2YUVQ@29|Myxococcales 28221|Deltaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, ATPase component - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran HSJS1_k127_2012196_1 485915.Dret_0676 2.279e-71 258.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2M8PZ@213115|Desulfovibrionales 28221|Deltaproteobacteria Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE HSJS1_k127_2012196_4 251221.35214391 1.043e-50 188.0 COG0787@1|root,COG0787@2|Bacteria,1G0IV@1117|Cyanobacteria 1117|Cyanobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N HSJS1_k127_2017767_6 426716.JOAJ01000011_gene6364 0.0006584 46.0 COG3361@1|root,COG3361@2|Bacteria,2GKQC@201174|Actinobacteria,4G2S7@85025|Nocardiaceae 201174|Actinobacteria S Uncharacterized conserved protein (COG2071) - - - - - - - - - - - - DUF2071 HSJS1_k127_2017767_0 502025.Hoch_2100 0.0 2012.0 COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,1P6RE@1224|Proteobacteria,43A2M@68525|delta/epsilon subdivisions,2X1XW@28221|Deltaproteobacteria,2YX2T@29|Myxococcales 28221|Deltaproteobacteria I Acetyl-CoA carboxylase, central region - - - - - - - - - - - - ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans HSJS1_k127_2017767_3 443143.GM18_1310 6.353e-82 289.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria 2|Bacteria QT Acyl-homoserine-lactone synthase - - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - AIRS,Acetyltransf_10,Acetyltransf_5,Aminotran_5 HSJS1_k127_2017767_4 1196028.ALEF01000037_gene829 1.033e-46 175.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 HSJS1_k127_2017767_5 1144275.COCOR_03629 4.828e-05 56.0 2EH77@1|root,33AZ1@2|Bacteria,1NMNZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2017767_2 1304284.L21TH_0712 6.334e-140 452.0 COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,2485S@186801|Clostridia,36FJ8@31979|Clostridiaceae 186801|Clostridia M RmlD substrate binding domain - - - - - - - - - - - - Epimerase HSJS1_k127_2017767_1 526227.Mesil_2957 7.017e-143 466.0 COG0156@1|root,COG0156@2|Bacteria,1WIXA@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide - GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HSJS1_k127_2028967_0 1232410.KI421412_gene169 2.256e-200 628.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,43SYA@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK HSJS1_k127_2028967_1 448385.sce0381 5.839e-22 106.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2028967_2 448385.sce0381 1.132e-12 72.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2029826_0 502025.Hoch_2528 3.462e-188 606.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_2033440_0 1144275.COCOR_06393 6.881e-188 597.0 COG0304@1|root,COG0304@2|Bacteria 2|Bacteria I 3-oxoacyl-[acyl-carrier-protein] synthase activity fabB - 2.3.1.179,2.3.1.180 ko:K09458,ko:K18473 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00082,M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119,R10707 RC00004,RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt HSJS1_k127_2033440_1 512565.AMIS_56490 1.365e-67 238.0 COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4DAU4@85008|Micromonosporales 201174|Actinobacteria K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 HSJS1_k127_2033440_2 702450.CUW_1055 5.542e-55 201.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,3VQK7@526524|Erysipelotrichia 526524|Erysipelotrichia E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC HSJS1_k127_2033440_3 1449357.JQLK01000001_gene1656 1.046e-33 141.0 COG1281@1|root,COG1281@2|Bacteria,1WJ1Y@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 HSJS1_k127_2034734_0 1038867.AXAY01000023_gene4617 6.343e-63 235.0 COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2U13E@28211|Alphaproteobacteria,3JXB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major intrinsic protein - - - - - - - - - - - - MIP HSJS1_k127_2034734_1 1173026.Glo7428_3906 4.937e-23 101.0 COG0604@1|root,COG0604@2|Bacteria,1G241@1117|Cyanobacteria 1117|Cyanobacteria C PFAM Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N HSJS1_k127_2035390_3 555079.Toce_1027 9.332e-73 256.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,42FC6@68295|Thermoanaerobacterales 186801|Clostridia J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N HSJS1_k127_2035390_0 240015.ACP_1472 5.587e-168 557.0 COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia 204432|Acidobacteriia D Ftsk_gamma - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma HSJS1_k127_2035390_5 187272.Mlg_0267 5.402e-33 148.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales 135613|Chromatiales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD HSJS1_k127_2035390_1 880073.Calab_2466 1.104e-121 401.0 COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria 2|Bacteria S ATPase associated with various cellular moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 HSJS1_k127_2035390_2 880073.Calab_2467 9.841e-81 280.0 COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - - - - - - - - - - DUF58 HSJS1_k127_2035390_6 1278073.MYSTI_06256 1.345e-05 58.0 2DQMB@1|root,337KD@2|Bacteria,1NKJH@1224|Proteobacteria,42X0X@68525|delta/epsilon subdivisions,2WSJT@28221|Deltaproteobacteria,2YVNT@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2035390_4 1191523.MROS_0397 1.675e-36 157.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA HSJS1_k127_2035558_1 243231.GSU0664 3.707e-84 289.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,43T1T@69541|Desulfuromonadales 28221|Deltaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C HSJS1_k127_2035558_3 1122197.ATWI01000008_gene2682 8.677e-06 57.0 COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria,468S7@72275|Alteromonadaceae 1236|Gammaproteobacteria S cellulase activity - - - - - - - - - - - - - HSJS1_k127_2035558_0 243090.RB13224 6.365e-181 580.0 COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes 203682|Planctomycetes GM PFAM NAD-dependent epimerase dehydratase - - - - - - - - - - - - DUF2867,NAD_binding_10 HSJS1_k127_2035558_2 935863.AWZR01000006_gene1206 2.289e-28 121.0 COG3391@1|root,COG3391@2|Bacteria,1R7H9@1224|Proteobacteria,1SGRP@1236|Gammaproteobacteria,1X57E@135614|Xanthomonadales 135614|Xanthomonadales S amine dehydrogenase activity - - - - - - - - - - - - Lactonase HSJS1_k127_2046448_9 404380.Gbem_3741 1.112e-10 64.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,43TUT@69541|Desulfuromonadales 28221|Deltaproteobacteria O repeat-containing protein - - - - - - - - - - - - Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8 HSJS1_k127_2046448_7 479434.Sthe_2534 2.013e-24 118.0 COG2373@1|root,COG3420@1|root,COG2373@2|Bacteria,COG3420@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia 2|Bacteria P alginic acid biosynthetic process - - - ko:K13735,ko:K21449 ko05100,map05100 - - - ko00000,ko00001,ko02000 1.B.40.2 - - Big_1,DUF3494,IAT_beta,Invasin_D3 HSJS1_k127_2046448_0 1122176.KB903572_gene4836 5.084e-251 818.0 COG1361@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - CHU_C,DUF11,PKD,SprB HSJS1_k127_2046448_1 1122176.KB903572_gene4836 7.503e-237 783.0 COG1361@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - CHU_C,DUF11,PKD,SprB HSJS1_k127_2046448_8 56780.SYN_01719 1.792e-14 78.0 COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WREY@28221|Deltaproteobacteria,2MSHX@213462|Syntrophobacterales 28221|Deltaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p HSJS1_k127_2046448_5 498848.TaqDRAFT_3584 1.261e-40 154.0 COG0292@1|root,COG0292@2|Bacteria,1WK7V@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 HSJS1_k127_2046448_4 316067.Geob_3361 1.276e-113 380.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,43TP6@69541|Desulfuromonadales 28221|Deltaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAF987.Gmet_1415 Phe_tRNA-synt_N,tRNA-synt_2d HSJS1_k127_2046448_3 518766.Rmar_0618 3.733e-119 410.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1FIKR@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Ferredoxin-fold anticodon binding domain pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind HSJS1_k127_2046448_10 278963.ATWD01000001_gene3801 3.614e-09 63.0 COG3027@1|root,COG3027@2|Bacteria,3Y83Q@57723|Acidobacteria,2JN6P@204432|Acidobacteriia 204432|Acidobacteriia D Cell division protein ZapA - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA HSJS1_k127_2046448_2 335543.Sfum_2578 1.78e-168 546.0 COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,2MQ65@213462|Syntrophobacterales 28221|Deltaproteobacteria A Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 HSJS1_k127_2046448_6 56780.SYN_02978 7.349e-26 109.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,2MR9H@213462|Syntrophobacterales 28221|Deltaproteobacteria S YmdB-like protein - - - ko:K09769 - - - - ko00000 - - - YmdB HSJS1_k127_2054746_1 1177181.T9A_00327 1.063e-46 171.0 COG0300@1|root,COG0300@2|Bacteria,1R7MT@1224|Proteobacteria,1S0XC@1236|Gammaproteobacteria,1XR3K@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short HSJS1_k127_2054746_0 1254432.SCE1572_50085 2.63e-299 946.0 COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2YUA8@29|Myxococcales 28221|Deltaproteobacteria J glutaminyl-tRNA glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C HSJS1_k127_2058182_1 864702.OsccyDRAFT_3998 1.382e-12 75.0 2DGQA@1|root,32U7P@2|Bacteria,1GB7Q@1117|Cyanobacteria,1HGSC@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_2058182_0 1384054.N790_09125 1.093e-106 356.0 COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,1R64W@1224|Proteobacteria,1RZ3W@1236|Gammaproteobacteria,1X59R@135614|Xanthomonadales 135614|Xanthomonadales L Ribonuclease - - - - - - - - - - - - Big_5,Endonuclease_1,LTD HSJS1_k127_2058182_2 319225.Plut_1835 5.055e-12 78.0 COG2856@1|root,COG2856@2|Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - Peptidase_M78 HSJS1_k127_2058182_3 448385.sce0381 1.978e-11 74.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2071406_0 309807.SRU_2566 2.301e-36 158.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1FJBA@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Oxygen tolerance - - - - - - - - - - - - BatD HSJS1_k127_2071406_2 1049564.TevJSym_bh00090 2.451e-06 60.0 COG0457@1|root,COG0457@2|Bacteria,1PYTB@1224|Proteobacteria,1RSFQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Tetratricopeptide - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_16 HSJS1_k127_2071406_1 1347342.BN863_33840 3.46e-07 63.0 COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia 976|Bacteroidetes S von Willebrand factor, type A batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 HSJS1_k127_2075779_1 448385.sce1159 3.054e-26 125.0 COG2911@1|root,COG2911@2|Bacteria,1N4HK@1224|Proteobacteria,438QH@68525|delta/epsilon subdivisions,2X912@28221|Deltaproteobacteria,2YXIA@29|Myxococcales 28221|Deltaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - HSJS1_k127_2075779_0 745411.B3C1_14882 2.143e-81 281.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1J4YU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec HSJS1_k127_2082244_6 684949.ATTJ01000001_gene2691 1.441e-25 108.0 COG1108@1|root,COG1108@2|Bacteria,1WMCX@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P ABC 3 transport family - - - ko:K11708 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3 HSJS1_k127_2082244_0 1089550.ATTH01000001_gene2470 1.202e-99 345.0 COG1121@1|root,COG1121@2|Bacteria,4NHZ9@976|Bacteroidetes,1FJZB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P ABC transporter troB - 3.6.3.35 ko:K11710,ko:K19973 ko02010,map02010 M00319,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 - - ABC_tran HSJS1_k127_2082244_1 1121346.KB899823_gene2377 3.608e-98 332.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,26R1W@186822|Paenibacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family troA - - ko:K11707 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA HSJS1_k127_2082244_3 583355.Caka_0239 2.799e-60 216.0 COG1321@1|root,COG1321@2|Bacteria,46T7C@74201|Verrucomicrobia,3K8J0@414999|Opitutae 414999|Opitutae K iron dependent repressor - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA HSJS1_k127_2082244_8 518766.Rmar_2787 3.519e-06 59.0 COG0457@1|root,COG0457@2|Bacteria 518766.Rmar_2787|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_2082244_2 583355.Caka_1975 2.376e-78 279.0 COG4148@1|root,COG4148@2|Bacteria,46YZT@74201|Verrucomicrobia,3K86D@414999|Opitutae 414999|Opitutae P TOBE domain - - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE HSJS1_k127_2082244_4 583355.Caka_1974 4.821e-60 225.0 COG4149@1|root,COG4149@2|Bacteria,46TVT@74201|Verrucomicrobia,3K813@414999|Opitutae 414999|Opitutae P Molybdate ABC transporter - - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 HSJS1_k127_2082244_5 1216966.BAUC01000016_gene540 1.791e-42 168.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC transporter, periplasmic molybdate-binding protein modA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - iECO111_1330.ECO111_0773,iPC815.YPO1145 SBP_bac_11 HSJS1_k127_2082244_9 2903.EOD19340 0.0003186 52.0 COG0500@1|root,KOG1541@2759|Eukaryota 2759|Eukaryota Q rRNA (guanine-N7)-methylation WBSCR27 - - - - - - - - - - - Methyltransf_11,Methyltransf_25 HSJS1_k127_2082244_7 41431.PCC8801_0348 8.058e-25 106.0 COG0528@1|root,COG0528@2|Bacteria 2|Bacteria F UMP kinase activity mosB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030151,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 2.7.4.22 ko:K00947,ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase HSJS1_k127_2087303_0 84531.JMTZ01000070_gene1816 2.603e-123 405.0 COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales 135614|Xanthomonadales I Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase HSJS1_k127_2087303_3 287.DR97_3129 4.618e-35 143.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1YCY9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006482,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0008214,GO:0008984,GO:0009605,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0018277,GO:0019538,GO:0019899,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051723,GO:0052689,GO:0070988,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1990827 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg HSJS1_k127_2087303_5 1123059.KB823011_gene1766 7.646e-11 70.0 COG2823@1|root,COG2823@2|Bacteria,1NJK0@1224|Proteobacteria,2U9XB@28211|Alphaproteobacteria,43XMZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S periplasmic or secreted lipoprotein osmY - - - - - - - - - - - BON HSJS1_k127_2087303_6 1238190.AMQY01000009_gene2241 0.000642 49.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 HSJS1_k127_2087303_4 373903.Hore_01460 1.057e-30 125.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3WAUY@53433|Halanaerobiales 186801|Clostridia J TIGRFAM ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 HSJS1_k127_2087303_1 204669.Acid345_1255 2.399e-117 386.0 COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia 204432|Acidobacteriia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L HSJS1_k127_2087303_2 398767.Glov_1372 1.848e-78 267.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 HSJS1_k127_2087699_0 1249997.JHZW01000002_gene1835 3.134e-142 481.0 COG0421@1|root,COG0421@2|Bacteria 2|Bacteria E spermidine synthase activity speE GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth HSJS1_k127_2089014_2 1128421.JAGA01000003_gene2874 8.781e-109 374.0 COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria 2|Bacteria P ABC-type Zn2 transport system, periplasmic component surface adhesin actF - - - - - - - - - - - - HSJS1_k127_2089014_5 234267.Acid_0493 2.854e-51 189.0 COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria 57723|Acidobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 HSJS1_k127_2089014_4 1128421.JAGA01000003_gene2872 5.768e-52 209.0 COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria 2|Bacteria C Protein of unknown function (DUF3341) - - - - - - - - - - - - DUF3341 HSJS1_k127_2089014_1 1128421.JAGA01000003_gene2871 2.874e-199 631.0 COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria 2|Bacteria C Polysulphide reductase, NrfD nrfD - - ko:K00185 - - - - ko00000 5.A.3 - - DUF3341,NrfD HSJS1_k127_2089014_0 1128421.JAGA01000003_gene2870 4.4e-323 1017.0 COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S dicluster domain hmeA - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molydop_binding HSJS1_k127_2089014_3 204669.Acid345_3004 4.76e-79 271.0 COG3880@1|root,COG3880@2|Bacteria,3Y2KG@57723|Acidobacteria,2JHTD@204432|Acidobacteriia 204432|Acidobacteriia S Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrome_C7 HSJS1_k127_2089014_6 926566.Terro_0968 0.0002383 48.0 COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia 204432|Acidobacteriia C Polysaccharide lyase family 4, domain II - - - - - - - - - - - - CarboxypepD_reg HSJS1_k127_2089350_1 1231190.NA8A_17448 6.674e-08 57.0 COG0438@1|root,COG0438@2|Bacteria,1QY5E@1224|Proteobacteria,2VF92@28211|Alphaproteobacteria,43MAQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4 HSJS1_k127_2089350_0 1536769.P40081_11720 1.202e-60 225.0 COG0438@1|root,COG0438@2|Bacteria,1URQU@1239|Firmicutes,4HC5Z@91061|Bacilli,26RJ6@186822|Paenibacillaceae 91061|Bacilli M Glycosyl transferase - - - - - - - - - - - - Glycos_transf_1 HSJS1_k127_209561_0 1515613.HQ37_03735 1.279e-125 410.0 COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,2FPXC@200643|Bacteroidia 976|Bacteroidetes H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD HSJS1_k127_209561_2 929712.KI912613_gene2832 6.885e-43 169.0 COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4CPXW@84995|Rubrobacteria 84995|Rubrobacteria P Anion-transporting ATPase - - - - - - - - - - - - ArsA_ATPase HSJS1_k127_209561_1 58123.JOFJ01000002_gene2423 1.175e-57 224.0 COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4EGPD@85012|Streptosporangiales 201174|Actinobacteria D Anion-transporting ATPase - - - - - - - - - - - - ArsA_ATPase HSJS1_k127_2095738_1 509635.N824_03760 1.36e-18 90.0 COG1075@1|root,COG1075@2|Bacteria,4NIEZ@976|Bacteroidetes 976|Bacteroidetes S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_2 HSJS1_k127_2095738_2 448385.sce0381 1.705e-09 68.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2095738_0 391625.PPSIR1_12068 2.927e-51 185.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales 28221|Deltaproteobacteria E Threonine dehydratase - - 4.3.1.17,4.3.1.19 ko:K17989 ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00590,R00996 RC00331,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP HSJS1_k127_2096012_4 278957.ABEA03000060_gene3074 1.85e-27 119.0 29F7N@1|root,3207C@2|Bacteria,46XQ7@74201|Verrucomicrobia,3K94A@414999|Opitutae 414999|Opitutae - - - - - - - - - - - - - - - HSJS1_k127_2096012_0 240016.ABIZ01000001_gene3192 4.653e-151 503.0 COG2268@1|root,COG2268@2|Bacteria,46XBU@74201|Verrucomicrobia,2IVCH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S prohibitin homologues - - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot HSJS1_k127_2096012_3 1123073.KB899242_gene1683 2.357e-40 165.0 2EP1Q@1|root,33GNJ@2|Bacteria,1NKYB@1224|Proteobacteria,1SH1F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DIE2/ALG10 family - - - - - - - - - - - - DIE2_ALG10 HSJS1_k127_2096012_5 1056820.KB900629_gene1756 3.496e-20 104.0 2EP1Q@1|root,33GNJ@2|Bacteria,1NKYB@1224|Proteobacteria,1SH1F@1236|Gammaproteobacteria,2PQ0M@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S DIE2/ALG10 family - - - - - - - - - - - - DIE2_ALG10 HSJS1_k127_2096012_1 1148.1652187 1.893e-68 241.0 COG1121@1|root,COG1121@2|Bacteria,1G2EJ@1117|Cyanobacteria,1H6B7@1142|Synechocystis 1117|Cyanobacteria P AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC_tran HSJS1_k127_2096012_2 679926.Mpet_2154 3.096e-58 222.0 COG1108@1|root,arCOG01006@2157|Archaea,2XTNB@28890|Euryarchaeota,2N9BQ@224756|Methanomicrobia 224756|Methanomicrobia P ABC 3 transport family - - - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - iAF692.Mbar_A0996 ABC-3 HSJS1_k127_2096012_6 243090.RB6151 8.763e-20 90.0 COG3361@1|root,COG3361@2|Bacteria,2IYZC@203682|Planctomycetes 203682|Planctomycetes S Uncharacterized conserved protein (COG2071) - - - - - - - - - - - - DUF2071 HSJS1_k127_2100412_10 1118054.CAGW01000032_gene697 1.229e-44 171.0 COG1319@1|root,COG1319@2|Bacteria,1TRPF@1239|Firmicutes,4HE74@91061|Bacilli,26RK5@186822|Paenibacillaceae 2|Bacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 HSJS1_k127_2100412_0 413816.BBJP01000008_gene561 6.88e-315 992.0 COG1529@1|root,arCOG01167@2157|Archaea,2XSZN@28890|Euryarchaeota,23S55@183963|Halobacteria 183963|Halobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 HSJS1_k127_2100412_7 479431.Namu_4148 5.184e-59 208.0 COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4ESSY@85013|Frankiales 201174|Actinobacteria C Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 HSJS1_k127_2100412_11 324602.Caur_3470 1.162e-36 147.0 COG3170@1|root,COG3427@1|root,COG3170@2|Bacteria,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia 32061|Chloroflexia NU PFAM carbon monoxide dehydrogenase subunit G - - - ko:K09386 - - - - ko00000 - - - COXG HSJS1_k127_2100412_12 1245471.PCA10_51040 2.694e-25 119.0 COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,1SHV8@1236|Gammaproteobacteria,1YH12@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - - - - - - - - - - ThiS HSJS1_k127_2100412_1 339670.Bamb_4563 1.459e-154 496.0 COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1K2TY@119060|Burkholderiaceae 28216|Betaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - - HSJS1_k127_2100412_13 84531.JMTZ01000062_gene1978 9.06e-14 76.0 2E7XS@1|root,332C8@2|Bacteria,1N9GD@1224|Proteobacteria,1SGBU@1236|Gammaproteobacteria,1X7NS@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - HSJS1_k127_2100412_8 118173.KB235914_gene764 4.832e-50 189.0 COG0454@1|root,COG0456@2|Bacteria,1G6J0@1117|Cyanobacteria 1117|Cyanobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 HSJS1_k127_2100412_4 195250.CM001776_gene3717 2.034e-81 273.0 COG4675@1|root,COG4675@2|Bacteria,1G6QH@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Phage Tail Collar Domain - - - - - - - - - - - - Collar HSJS1_k127_2100412_5 329726.AM1_3689 9.677e-80 274.0 COG4675@1|root,COG4675@2|Bacteria,1G7A6@1117|Cyanobacteria 1117|Cyanobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar HSJS1_k127_2100412_6 329726.AM1_3688 1.595e-76 259.0 COG4675@1|root,COG4675@2|Bacteria,1G7MZ@1117|Cyanobacteria 1117|Cyanobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar HSJS1_k127_2100412_3 313589.JNB_03025 6.855e-99 368.0 COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,2HY2Q@201174|Actinobacteria,4FJJC@85021|Intrasporangiaceae 201174|Actinobacteria MU Parallel beta-helix repeats - - - - - - - - - - - - Big_5 HSJS1_k127_2100412_14 351016.RAZWK3B_13899 3.87e-07 59.0 COG5652@1|root,COG5652@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - VanZ HSJS1_k127_2100412_9 391587.KAOT1_15988 3.347e-46 173.0 COG1652@1|root,COG1652@2|Bacteria,4NMED@976|Bacteroidetes,1I1AU@117743|Flavobacteriia 976|Bacteroidetes S Lysin motif - - - - - - - - - - - - BON,LysM HSJS1_k127_2100412_2 671143.DAMO_3123 3.504e-104 347.0 COG2204@1|root,COG2204@2|Bacteria,2NQHI@2323|unclassified Bacteria 2|Bacteria T Sigma-54 interaction domain - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_2106679_1 1396141.BATP01000057_gene3001 8.127e-07 56.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_ECF HSJS1_k127_2106679_0 1122947.FR7_2760 7.507e-36 143.0 29XA7@1|root,30IZT@2|Bacteria,1W1FQ@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - HSJS1_k127_2117888_1 1267534.KB906754_gene2687 4.921e-16 81.0 COG0308@1|root,COG0308@2|Bacteria,3Y71N@57723|Acidobacteria,2JMDX@204432|Acidobacteriia 204432|Acidobacteriia E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 HSJS1_k127_2117888_0 706587.Desti_3137 2.045e-162 540.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2MQ5N@213462|Syntrophobacterales 28221|Deltaproteobacteria O Protein of unknown function, DUF255 yyaL - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH HSJS1_k127_2121782_2 867903.ThesuDRAFT_01636 9.542e-31 138.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia 186801|Clostridia G Belongs to the glycerate kinase type-1 family - - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase HSJS1_k127_2121782_1 649638.Trad_1694 2.97e-34 147.0 COG2267@1|root,COG2267@2|Bacteria,1WJIG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 HSJS1_k127_2121782_0 309807.SRU_1748 5.175e-57 218.0 COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1FIVK@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M D-Ala-D-Ala carboxypeptidase 3 (S13) family - - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 HSJS1_k127_2125214_2 1536774.H70357_33280 9.949e-09 66.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,26SK4@186822|Paenibacillaceae 91061|Bacilli KL ATP-dependent helicase uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 HSJS1_k127_2125214_1 649638.Trad_0038 3.266e-40 167.0 COG1207@1|root,COG1207@2|Bacteria 2|Bacteria M glucosamine-1-phosphate N-acetyltransferase activity glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep HSJS1_k127_2125214_0 760011.Spico_0358 6.685e-48 179.0 COG2094@1|root,COG2094@2|Bacteria,2J8XZ@203691|Spirochaetes 203691|Spirochaetes L Belongs to the DNA glycosylase MPG family mag - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco HSJS1_k127_2125879_5 448385.sce0381 1.56e-23 108.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2125879_2 351160.RRC7 2.812e-36 142.0 COG3603@1|root,arCOG05233@2157|Archaea,2Y1ZW@28890|Euryarchaeota,2NB8G@224756|Methanomicrobia 224756|Methanomicrobia S ACT domain - - - ko:K09707 - - - - ko00000 - - - ACT_7 HSJS1_k127_2125879_4 1266925.JHVX01000006_gene2114 2.383e-24 119.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2W9RH@28216|Betaproteobacteria,3744M@32003|Nitrosomonadales 28216|Betaproteobacteria S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 HSJS1_k127_2125879_1 555088.DealDRAFT_0482 2.499e-42 180.0 COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 HSJS1_k127_2125879_0 1278073.MYSTI_05937 1.444e-147 481.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales 28221|Deltaproteobacteria I Belongs to the thiolase family fadI - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N HSJS1_k127_2125879_6 1232410.KI421412_gene342 1.761e-12 79.0 2DKA3@1|root,30905@2|Bacteria,1RGG6@1224|Proteobacteria 1224|Proteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 HSJS1_k127_2125879_3 1286106.MPL1_00457 3.96e-30 140.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,461X9@72273|Thiotrichales 72273|Thiotrichales NU Type IV fimbrial biogenesis protein PilY1 - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC HSJS1_k127_2127303_0 269800.Tfu_1179 1.779e-109 372.0 COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4EFJS@85012|Streptosporangiales 201174|Actinobacteria G Pyruvate kinase, barrel domain pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C HSJS1_k127_2127495_5 298654.FraEuI1c_6078 7.41e-12 74.0 COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4ETXA@85013|Frankiales 201174|Actinobacteria M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 HSJS1_k127_2127495_2 443143.GM18_4174 2.243e-29 132.0 COG0457@1|root,COG0463@1|root,COG1216@1|root,COG2227@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1P77I@1224|Proteobacteria,42TJP@68525|delta/epsilon subdivisions,2WR5S@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,TPR_8 HSJS1_k127_2127495_4 1246995.AFR_16010 1.451e-18 98.0 COG1216@1|root,COG1216@2|Bacteria,2I5Z7@201174|Actinobacteria,4DFNY@85008|Micromonosporales 201174|Actinobacteria S Glycosyltransferase like family 2 - - 2.4.1.289 ko:K16870 - - - - ko00000,ko01000,ko01003 - - - Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2 HSJS1_k127_2127495_3 1283300.ATXB01000001_gene2334 2.221e-24 115.0 COG2227@1|root,COG2227@2|Bacteria,1RAW1@1224|Proteobacteria,1S3J6@1236|Gammaproteobacteria,1XGSG@135618|Methylococcales 135618|Methylococcales H Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_9 HSJS1_k127_2127495_0 338966.Ppro_2693 7.643e-62 227.0 COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7KP@28221|Deltaproteobacteria,43V18@69541|Desulfuromonadales 28221|Deltaproteobacteria H Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_2127495_1 1128421.JAGA01000003_gene3091 2.156e-36 160.0 COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria 2|Bacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - YfhO HSJS1_k127_2127750_0 1191523.MROS_0751 2.302e-198 650.0 COG0286@1|root,COG0286@2|Bacteria 2|Bacteria V site-specific DNA-methyltransferase (adenine-specific) activity - - - - - - - - - - - - N6_Mtase HSJS1_k127_2127750_2 243233.MCA2791 2.95e-157 507.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XEKQ@135618|Methylococcales 135618|Methylococcales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas HSJS1_k127_2127750_4 272134.KB731324_gene3531 1.373e-05 56.0 COG0860@1|root,COG0860@2|Bacteria,1G008@1117|Cyanobacteria,1H876@1150|Oscillatoriales 1117|Cyanobacteria M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 HSJS1_k127_2127750_3 570268.ANBB01000037_gene2806 3.128e-39 155.0 COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4EHU5@85012|Streptosporangiales 201174|Actinobacteria GL Phosphoglycerate mutase family rnhA GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 ko:K02226,ko:K22316 ko00860,ko01100,ko03030,map00860,map01100,map03030 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000,ko03032 - - - His_Phos_1,RVT_3 HSJS1_k127_2127750_1 204669.Acid345_3065 1.833e-192 623.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO HSJS1_k127_2130752_1 502025.Hoch_2041 7.994e-73 253.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria 68525|delta/epsilon subdivisions KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase HSJS1_k127_2130752_0 869210.Marky_1844 1.466e-157 513.0 COG2223@1|root,COG2223@2|Bacteria,1WJJV@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P Major Facilitator Superfamily - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 HSJS1_k127_2130752_2 331678.Cphamn1_1986 2.156e-60 223.0 COG1290@1|root,COG1290@2|Bacteria,1FD8I@1090|Chlorobi 1090|Chlorobi C PFAM Cytochrome b b6 - - - ko:K02635 ko00195,ko01100,map00195,map01100 M00162 - - ko00000,ko00001,ko00002,ko00194 - - - Cytochrom_B_C,Cytochrome_B HSJS1_k127_2130752_3 525904.Tter_2537 1.514e-08 63.0 COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636 ko00195,ko01100,map00195,map01100 M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske HSJS1_k127_2133262_2 263358.VAB18032_07965 0.0001647 55.0 COG0457@1|root,COG0467@1|root,COG0457@2|Bacteria,COG0467@2|Bacteria,2INUN@201174|Actinobacteria,4DMN7@85008|Micromonosporales 201174|Actinobacteria K TPR repeat - - - - - - - - - - - - NB-ARC,TPR_12,TPR_8 HSJS1_k127_2133262_1 234267.Acid_4318 7.465e-121 407.0 COG3193@1|root,COG3193@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Haem_degrading HSJS1_k127_2133262_0 1123508.JH636445_gene6642 1.234e-146 499.0 COG3827@1|root,COG3827@2|Bacteria,2IXVY@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_2135095_1 903818.KI912268_gene2181 1.196e-70 269.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_2135095_3 1385935.N836_06220 2.693e-52 195.0 COG2227@1|root,COG2227@2|Bacteria,1GQNW@1117|Cyanobacteria,1HFA0@1150|Oscillatoriales 1117|Cyanobacteria H Methylase involved in ubiquinone menaquinone biosynthesis - - - - - - - - - - - - Methyltransf_25 HSJS1_k127_2135095_0 1122194.AUHU01000013_gene689 5.441e-107 363.0 COG1621@1|root,COG1621@2|Bacteria,1MWTX@1224|Proteobacteria,1RRZ2@1236|Gammaproteobacteria,46687@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.65,3.2.1.80 ko:K01212,ko:K03332 ko00051,ko00500,map00051,map00500 - R00879,R05624,R11311 RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N HSJS1_k127_2135095_5 1121920.AUAU01000009_gene1864 1.73e-32 147.0 COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria 57723|Acidobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - HSJS1_k127_2135095_2 530564.Psta_4322 6.926e-55 197.0 COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes 203682|Planctomycetes M COG2335 Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - Fasciclin HSJS1_k127_2135095_4 1120966.AUBU01000008_gene2572 4.805e-40 155.0 COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,47R93@768503|Cytophagia 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2147) - - - - - - - - - - - - DUF2147 HSJS1_k127_2135095_7 448385.sce4475 8.196e-13 81.0 COG3215@1|root,COG3215@2|Bacteria,1QR4G@1224|Proteobacteria,4352F@68525|delta/epsilon subdivisions,2WZDD@28221|Deltaproteobacteria,2Z1W5@29|Myxococcales 28221|Deltaproteobacteria NU PilZ domain - - - - - - - - - - - - PilZ HSJS1_k127_2135095_6 292415.Tbd_2424 1.307e-22 104.0 COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,1KRA7@119069|Hydrogenophilales 119069|Hydrogenophilales L THUMP - - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 HSJS1_k127_2146897_0 204669.Acid345_2310 8.094e-91 311.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia 204432|Acidobacteriia T Tetratricopeptide repeat - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_12 HSJS1_k127_2146897_2 391625.PPSIR1_00465 5.546e-63 229.0 COG3809@1|root,COG3809@2|Bacteria 2|Bacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - zf-TFIIB HSJS1_k127_2146897_1 502025.Hoch_0260 9.05e-68 237.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2WK7V@28221|Deltaproteobacteria,2YTWG@29|Myxococcales 28221|Deltaproteobacteria E phospho-2-dehydro-3-deoxyheptonate aldolase - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 HSJS1_k127_214797_3 1499967.BAYZ01000075_gene2072 1.735e-09 64.0 COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif pulG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG HSJS1_k127_214797_2 1121104.AQXH01000001_gene2093 9.298e-15 86.0 2E7CK@1|root,331VT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_214797_1 1267535.KB906767_gene4499 2.542e-40 162.0 COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia 204432|Acidobacteriia K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_214797_0 1089550.ATTH01000001_gene1831 2.103e-153 520.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_214797_4 682795.AciX8_1765 4.181e-05 58.0 COG3209@1|root,COG3209@2|Bacteria,3Y5Q3@57723|Acidobacteria,2JJZC@204432|Acidobacteriia 204432|Acidobacteriia M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat HSJS1_k127_2152275_0 215803.DB30_7949 5.667e-246 781.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales 28221|Deltaproteobacteria L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 HSJS1_k127_2152275_1 595460.RRSWK_05281 8.035e-78 281.0 COG1808@1|root,COG1808@2|Bacteria 2|Bacteria S Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 HSJS1_k127_2158315_9 1123322.KB904691_gene4450 8.861e-24 115.0 COG0702@1|root,COG0702@2|Bacteria,2IQ0Z@201174|Actinobacteria 201174|Actinobacteria GM NmrA-like family - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Methyltransf_21,NAD_binding_10 HSJS1_k127_2158315_1 1123322.KB904691_gene4451 2.124e-115 401.0 COG0365@1|root,COG0365@2|Bacteria 2|Bacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - - - - - - - - - - - AMP-binding,AMP-binding_C,PP-binding HSJS1_k127_2158315_4 1123322.KB904691_gene4452 4.085e-54 207.0 COG0304@1|root,COG0304@2|Bacteria,2I8V9@201174|Actinobacteria 201174|Actinobacteria IQ Beta-ketoacyl synthase, C-terminal domain - - - - - - - - - - - - Ketoacyl-synt_C,ketoacyl-synt HSJS1_k127_2158315_2 1961.JOAK01000012_gene6193 9.66e-108 363.0 COG0304@1|root,COG0304@2|Bacteria,2GNT4@201174|Actinobacteria 201174|Actinobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.179,2.3.1.235,2.3.1.260 ko:K05551,ko:K09458 ko00061,ko00253,ko00780,ko01056,ko01100,ko01130,ko01212,map00061,map00253,map00780,map01056,map01100,map01130,map01212 M00083,M00572,M00778 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R06635,R06637,R06641,R06643,R06644,R06645,R07762,R09258,R09259,R10115,R10119,R10960,R11516 RC00004,RC00039,RC02545,RC02728,RC02729,RC02888,RC02931,RC02932,RC02947 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Ketoacyl-synt_C,ketoacyl-synt HSJS1_k127_2158315_11 720555.BATR1942_00915 1.661e-06 55.0 COG0236@1|root,COG0236@2|Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding HSJS1_k127_2158315_12 1120973.AQXL01000126_gene2918 7.777e-05 55.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,279RF@186823|Alicyclobacillaceae 91061|Bacilli H UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA HSJS1_k127_2158315_7 1337093.MBE-LCI_1620 3.45e-36 151.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,2P8MU@245186|Loktanella 28211|Alphaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt HSJS1_k127_2158315_10 552811.Dehly_0135 7.761e-22 107.0 COG0500@1|root,COG2226@2|Bacteria,2G9AJ@200795|Chloroflexi,34D6A@301297|Dehalococcoidia 301297|Dehalococcoidia H Methyltransferase domain - - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_25 HSJS1_k127_2158315_3 1123322.KB904691_gene4455 1.296e-55 209.0 2A393@1|root,30RQZ@2|Bacteria,2H6EF@201174|Actinobacteria 201174|Actinobacteria S UbiA prenyltransferase family - - - - - - - - - - - - UbiA HSJS1_k127_2158315_5 1463921.JODF01000001_gene4039 4.851e-45 177.0 COG1657@1|root,COG1657@2|Bacteria,2GVYS@201174|Actinobacteria 201174|Actinobacteria I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - SQHop_cyclase_C HSJS1_k127_2158315_8 1282360.ABAC460_13335 4.878e-36 156.0 COG5379@1|root,COG5379@2|Bacteria,1MWG8@1224|Proteobacteria,2TQKH@28211|Alphaproteobacteria 28211|Alphaproteobacteria I S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase - - - - - - - - - - - - DUF3419 HSJS1_k127_2158315_6 383372.Rcas_0523 2.728e-36 150.0 COG0346@1|root,COG0346@2|Bacteria,2G8K0@200795|Chloroflexi,37776@32061|Chloroflexia 32061|Chloroflexia E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 HSJS1_k127_2158315_0 1121957.ATVL01000011_gene3937 1.419e-120 401.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47KM9@768503|Cytophagia 976|Bacteroidetes H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid kmo - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 HSJS1_k127_2163925_0 1499967.BAYZ01000195_gene3106 3.926e-56 201.0 COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria 2|Bacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase MA20_19960 - - - - - - - - - - - PMT_2 HSJS1_k127_2166036_1 378806.STAUR_7235 2.412e-103 355.0 2AQ29@1|root,31F7C@2|Bacteria,1NHC1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2166036_2 56110.Oscil6304_4744 2.954e-80 278.0 COG1028@1|root,COG1028@2|Bacteria,1G02R@1117|Cyanobacteria,1H9PG@1150|Oscillatoriales 1117|Cyanobacteria IQ Short chain dehydrogenase - - - - - - - - - - - - adh_short HSJS1_k127_2166036_0 1382359.JIAL01000001_gene577 4.771e-235 743.0 COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia 204432|Acidobacteriia T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 HSJS1_k127_2174434_3 926550.CLDAP_01840 1.27e-55 200.0 COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi 200795|Chloroflexi C PFAM Transketolase central region - - - - - - - - - - - - Transket_pyr,Transketolase_C HSJS1_k127_2174434_0 266117.Rxyl_0486 1.575e-172 559.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria 84995|Rubrobacteria L DNA polymerase X - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_thumb,HHH_5,HHH_8,PHP HSJS1_k127_2174434_1 1382359.JIAL01000001_gene2704 1.436e-161 526.0 COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria,2JHR4@204432|Acidobacteriia 204432|Acidobacteriia S Insulinase (Peptidase family M16) - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_2174434_2 204669.Acid345_0621 1.819e-145 487.0 COG0612@1|root,COG0612@2|Bacteria,3Y322@57723|Acidobacteria,2JP25@204432|Acidobacteriia 204432|Acidobacteriia S Peptidase M16 inactive domain - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16_C HSJS1_k127_2185733_8 247490.KSU1_C0095 1.717e-29 129.0 COG0398@1|root,COG0398@2|Bacteria,2IZA9@203682|Planctomycetes 203682|Planctomycetes S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc HSJS1_k127_2185733_10 1162668.LFE_1682 5.318e-10 70.0 COG2924@1|root,COG2924@2|Bacteria,3J1CU@40117|Nitrospirae 40117|Nitrospirae C Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - - - - - - - - - - Iron_traffic HSJS1_k127_2185733_1 497964.CfE428DRAFT_4613 3.91e-146 470.0 COG0451@1|root,COG0451@2|Bacteria,46S80@74201|Verrucomicrobia 74201|Verrucomicrobia GM GDP-mannose 4,6 dehydratase - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd HSJS1_k127_2185733_0 644282.Deba_2080 9.763e-169 544.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N HSJS1_k127_2185733_2 667014.Thein_1217 5.781e-108 378.0 COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Male sterility protein - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd HSJS1_k127_2185733_7 269799.Gmet_2541 5.717e-37 160.0 COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43TRY@69541|Desulfuromonadales 28221|Deltaproteobacteria Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD HSJS1_k127_2185733_5 644282.Deba_0203 1.55e-71 250.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran HSJS1_k127_2185733_4 671143.DAMO_2629 1.787e-75 261.0 COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE HSJS1_k127_2185733_6 1123371.ATXH01000001_gene1304 5.326e-48 184.0 COG0204@1|root,COG0204@2|Bacteria,2GH4C@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase HSJS1_k127_2185733_3 880073.Calab_1244 2.846e-103 361.0 COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria 2|Bacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA HSJS1_k127_2185733_9 1120963.KB894502_gene1301 9.505e-15 83.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,2Q0R7@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - iE2348C_1286.E2348C_0457 Metallophos,Metallophos_2 HSJS1_k127_2201002_3 1382356.JQMP01000003_gene1474 7.113e-116 381.0 COG1878@1|root,COG1878@2|Bacteria,2GBE2@200795|Chloroflexi,27Z29@189775|Thermomicrobia 189775|Thermomicrobia S Putative cyclase - - - - - - - - - - - - Cyclase HSJS1_k127_2201002_0 196490.AUEZ01000042_gene7227 0.0 1109.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 HSJS1_k127_2201002_1 335543.Sfum_1617 7.577e-189 608.0 COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_2201002_4 335543.Sfum_1616 3.677e-75 281.0 COG0457@1|root,COG0457@2|Bacteria,1PFBA@1224|Proteobacteria,43755@68525|delta/epsilon subdivisions,2WQN6@28221|Deltaproteobacteria,2MSBR@213462|Syntrophobacterales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 HSJS1_k127_2201002_2 63737.Npun_R4594 2.833e-186 603.0 COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria,1HQNE@1161|Nostocales 1117|Cyanobacteria IQ AMP-binding enzyme C-terminal domain - - - ko:K00666,ko:K18660 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C HSJS1_k127_2201002_5 518766.Rmar_1418 4.15e-32 130.0 COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1FJTB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E FAD dependent oxidoreductase - - - - - - - - - - - - DAO HSJS1_k127_2201153_1 497965.Cyan7822_4395 6.089e-06 53.0 2E5P1@1|root,330DP@2|Bacteria,1G84E@1117|Cyanobacteria 1117|Cyanobacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 HSJS1_k127_2201153_0 1128421.JAGA01000002_gene1368 6.514e-310 972.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2NNW4@2323|unclassified Bacteria 2|Bacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase HSJS1_k127_220142_1 935863.AWZR01000006_gene1206 4.407e-39 159.0 COG3391@1|root,COG3391@2|Bacteria,1R7H9@1224|Proteobacteria,1SGRP@1236|Gammaproteobacteria,1X57E@135614|Xanthomonadales 135614|Xanthomonadales S amine dehydrogenase activity - - - - - - - - - - - - Lactonase HSJS1_k127_220142_0 639282.DEFDS_1225 2.542e-215 681.0 COG1884@1|root,COG1884@2|Bacteria,2GF64@200930|Deferribacteres 200930|Deferribacteres I Methylmalonyl-CoA mutase - - 5.4.99.2 ko:K01847,ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase HSJS1_k127_220142_2 1499967.BAYZ01000125_gene2598 8.975e-30 138.0 COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria 2|Bacteria P Sulfatase - - - - - - - - - - - - CBM60,Sulfatase HSJS1_k127_2205117_1 1254432.SCE1572_37565 6.082e-32 145.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MWVZ@1224|Proteobacteria,43APJ@68525|delta/epsilon subdivisions,2X638@28221|Deltaproteobacteria,2Z38P@29|Myxococcales 28221|Deltaproteobacteria KLT Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase HSJS1_k127_2205117_2 330084.JNYZ01000013_gene5828 1.286e-29 128.0 COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4DXS2@85010|Pseudonocardiales 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigM GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_2205117_0 338966.Ppro_2244 1.173e-54 204.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,43SCR@69541|Desulfuromonadales 28221|Deltaproteobacteria P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA HSJS1_k127_2211759_1 243231.GSU1437 7.338e-55 203.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,43SFX@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM peptidase M48 Ste24p - - - - - - - - - - - iAF987.Gmet_1238 Peptidase_M48,TPR_14,TPR_16,TPR_19 HSJS1_k127_2211759_0 582515.KR51_00014290 4.823e-65 232.0 COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria 1117|Cyanobacteria S COGs COG2912 conserved - - - - - - - - - - - - TPR_9,Transglut_core2 HSJS1_k127_2211759_3 1205753.A989_04291 0.000393 48.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RZI1@1236|Gammaproteobacteria,1X6R7@135614|Xanthomonadales 135614|Xanthomonadales P Chloride channel protein EriC - - - - - - - - - - - - Voltage_CLC HSJS1_k127_2211759_2 1232410.KI421421_gene3877 8.651e-46 177.0 COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,43S7R@69541|Desulfuromonadales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM HSJS1_k127_222205_2 243231.GSU3460 6.626e-75 260.0 COG1215@1|root,COG2344@1|root,COG1215@2|Bacteria,COG2344@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,43S6T@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_222205_1 1265502.KB905969_gene1242 4.108e-81 302.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria 28216|Betaproteobacteria EGP Major facilitator Superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 HSJS1_k127_222205_0 926550.CLDAP_28320 5.784e-151 498.0 COG0699@1|root,COG0699@2|Bacteria,2G5JQ@200795|Chloroflexi 200795|Chloroflexi S PFAM Dynamin family protein - - - - - - - - - - - - Dynamin_N HSJS1_k127_222887_2 1313301.AUGC01000001_gene1720 0.0004207 45.0 COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes 976|Bacteroidetes E Cys/Met metabolism PLP-dependent enzyme - - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP HSJS1_k127_222887_0 234267.Acid_0690 3.31e-171 569.0 COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria 57723|Acidobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII HSJS1_k127_222887_1 324602.Caur_0217 3.314e-83 289.0 COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,374YR@32061|Chloroflexia 32061|Chloroflexia C Belongs to the aspartate-semialdehyde dehydrogenase family - - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC HSJS1_k127_222933_2 1048983.EL17_17645 1.25e-24 113.0 COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PSU@768503|Cytophagia 976|Bacteroidetes S PFAM MORN repeat variant - - - - - - - - - - - - MORN_2 HSJS1_k127_222933_1 1410620.SHLA_16c000450 3.039e-53 190.0 COG4104@1|root,COG4104@2|Bacteria,1N2DB@1224|Proteobacteria 1224|Proteobacteria S PAAR motif - - - - - - - - - - - - PAAR_motif HSJS1_k127_222933_0 1123242.JH636435_gene1504 9.83e-100 336.0 COG0500@1|root,COG2226@2|Bacteria,2J1W2@203682|Planctomycetes 203682|Planctomycetes Q Methyltransferase domain - - - - - - - - - - - - - HSJS1_k127_2229445_1 945713.IALB_1070 8.695e-53 190.0 COG1012@1|root,COG1012@2|Bacteria 2|Bacteria C belongs to the aldehyde dehydrogenase family pruA - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh HSJS1_k127_2229445_3 497321.C664_03305 7.948e-27 113.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,2VW3M@28216|Betaproteobacteria,2KX9W@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF423) - - - - - - - - - - - - DUF423 HSJS1_k127_2229445_2 682795.AciX8_2449 6.062e-48 181.0 28NYH@1|root,2ZBVN@2|Bacteria 2|Bacteria S Belongs to the UPF0403 family yqiW - - - - - - - - - - - Disulph_isomer HSJS1_k127_2229445_0 880073.Calab_0802 6.794e-127 416.0 COG0591@1|root,COG0591@2|Bacteria,2NPAX@2323|unclassified Bacteria 2|Bacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF HSJS1_k127_2233823_2 485913.Krac_6666 4.695e-13 74.0 COG1290@1|root,COG1290@2|Bacteria 2|Bacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis pcmD - - - - - - - - - - - Cytochrom_B_C,Cytochrome_B HSJS1_k127_2233823_0 671143.DAMO_1669 5.413e-77 286.0 COG0845@1|root,COG2010@1|root,COG0845@2|Bacteria,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,FIVAR,HlyD_3,PA14,RNA_pol_Rpb1_5 HSJS1_k127_2233823_1 247490.KSU1_B0263 3.982e-15 88.0 COG2010@1|root,COG2010@2|Bacteria,2J3VF@203682|Planctomycetes 203682|Planctomycetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 HSJS1_k127_2239882_2 1210884.HG799470_gene14506 6.588e-38 165.0 COG0584@1|root,COG0584@2|Bacteria,2J1MH@203682|Planctomycetes 203682|Planctomycetes C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD HSJS1_k127_2239882_1 1173027.Mic7113_2535 6.433e-47 194.0 COG0515@1|root,COG0515@2|Bacteria,1G08U@1117|Cyanobacteria,1H85Z@1150|Oscillatoriales 1117|Cyanobacteria KLT PFAM Protein kinase domain - - - - - - - - - - - - Pentapeptide,Pkinase HSJS1_k127_2239882_0 518766.Rmar_0497 1.477e-172 556.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1FKD5@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 HSJS1_k127_2241024_1 861299.J421_1911 3.999e-26 118.0 COG1278@1|root,COG1278@2|Bacteria 2|Bacteria K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD HSJS1_k127_2241024_0 237368.SCABRO_02555 3.058e-152 497.0 COG1966@1|root,COG1966@2|Bacteria,2IWZE@203682|Planctomycetes 203682|Planctomycetes T Carbon starvation protein cstA - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM HSJS1_k127_2244586_2 330214.NIDE0577 4.56e-73 268.0 COG0433@1|root,COG0433@2|Bacteria 2|Bacteria S helicase activity - - - - - - - - - - - - DUF853,DUF87 HSJS1_k127_2244586_3 765912.Thimo_1140 7.41e-66 251.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales 135613|Chromatiales H Belongs to the ribF family - - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase HSJS1_k127_2244586_0 1382359.JIAL01000001_gene2795 8.754e-123 409.0 COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia 204432|Acidobacteriia H Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,UPF0004 HSJS1_k127_2244586_1 56110.Oscil6304_1839 6.384e-91 314.0 COG4222@1|root,COG4222@2|Bacteria,1G00S@1117|Cyanobacteria 1117|Cyanobacteria C PFAM Phytase - - - - - - - - - - - - Phytase-like HSJS1_k127_2244586_5 1232410.KI421428_gene1001 2.131e-16 93.0 COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43UDD@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function, DUF480 - - - ko:K09915 - - - - ko00000 - - - DUF480 HSJS1_k127_2244586_4 1123393.KB891330_gene877 4.189e-17 87.0 COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,1KSRP@119069|Hydrogenophilales 119069|Hydrogenophilales S Protein of unknown function, DUF480 - - - - - - - - - - - - DUF480 HSJS1_k127_224773_1 1121920.AUAU01000026_gene1478 1.396e-31 134.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB_2 HSJS1_k127_224773_0 1521187.JPIM01000008_gene2107 4.664e-192 614.0 COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,3768X@32061|Chloroflexia 32061|Chloroflexia G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - DUF3536,Glyco_hydro_57 HSJS1_k127_224773_3 1267534.KB906755_gene4541 6.498e-07 62.0 2DBAV@1|root,2Z84I@2|Bacteria,3Y2PF@57723|Acidobacteria,2JIIF@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - HSJS1_k127_224773_2 234267.Acid_4013 1.445e-13 85.0 COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria 57723|Acidobacteria S oxidoreductase activity - - - - - - - - - - - - - HSJS1_k127_2253850_0 247490.KSU1_C0857 2.001e-122 398.0 COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes 203682|Planctomycetes S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 HSJS1_k127_2253850_1 237368.SCABRO_01880 5.402e-96 333.0 COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes 203682|Planctomycetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 HSJS1_k127_2253850_6 716544.wcw_1873 2.869e-10 72.0 2DVD0@1|root,33VC5@2|Bacteria,2JGZN@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - HSJS1_k127_2253850_3 1131269.AQVV01000007_gene1019 8.91e-88 302.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA HSJS1_k127_2253850_2 1131269.AQVV01000007_gene1020 7.569e-88 318.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 HSJS1_k127_2253850_5 316274.Haur_4899 2.743e-11 75.0 COG0457@1|root,COG0457@2|Bacteria 316274.Haur_4899|- S peptidyl-tyrosine sulfation - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - - HSJS1_k127_2253850_7 1280001.BAOA01000174_gene1 0.0002086 53.0 COG3266@1|root,COG3266@2|Bacteria,1R230@1224|Proteobacteria,1T60F@1236|Gammaproteobacteria,1XZHC@135623|Vibrionales 1224|Proteobacteria S domain, Protein - - - - - - - - - - - - - HSJS1_k127_2253850_4 1191523.MROS_0394 3.382e-56 222.0 COG0457@1|root,COG0457@2|Bacteria 1191523.MROS_0394|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_2254226_1 926569.ANT_10890 9.57e-54 198.0 COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM metal dependent phophohydrolase - - - - - - - - - - - - HD HSJS1_k127_2254226_3 1128421.JAGA01000003_gene3641 6.092e-35 142.0 COG1999@1|root,COG1999@2|Bacteria,2NRAY@2323|unclassified Bacteria 2|Bacteria S SCO1/SenC hyaE GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - ko:K03619,ko:K07152 - - - - ko00000,ko03029 - - - HyaE,SCO1-SenC HSJS1_k127_2254226_0 1121918.ARWE01000001_gene2375 3.066e-243 771.0 COG0531@1|root,COG1762@1|root,COG0531@2|Bacteria,COG1762@2|Bacteria,1MXNJ@1224|Proteobacteria,43A4W@68525|delta/epsilon subdivisions,2X2I0@28221|Deltaproteobacteria,43VI8@69541|Desulfuromonadales 28221|Deltaproteobacteria E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 HSJS1_k127_2255096_1 243231.GSU0302 4.742e-25 106.0 COG1916@1|root,COG1916@2|Bacteria,1R5SH@1224|Proteobacteria,42Q6N@68525|delta/epsilon subdivisions,2WKNS@28221|Deltaproteobacteria,43U80@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2255096_0 344747.PM8797T_15883 7.776e-71 263.0 COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,2IXUA@203682|Planctomycetes 203682|Planctomycetes C amine dehydrogenase activity - - - - - - - - - - - - CCP_MauG,Cytochrom_C HSJS1_k127_2255096_2 83406.HDN1F_14640 4.255e-14 78.0 COG0517@1|root,COG0517@2|Bacteria,1QFCA@1224|Proteobacteria,1RXQA@1236|Gammaproteobacteria,1JBAK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS HSJS1_k127_2263833_1 1089550.ATTH01000001_gene2237 7.064e-48 183.0 COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes 976|Bacteroidetes K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_2263833_0 1089550.ATTH01000001_gene1831 4.424e-131 443.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_2286289_0 502025.Hoch_0546 2.398e-98 336.0 COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2YV19@29|Myxococcales 28221|Deltaproteobacteria J Ribosomal protein S1-like RNA-binding domain - - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 HSJS1_k127_2286289_2 1437882.AZRU01000010_gene620 1.319e-32 146.0 COG0517@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,1YEHS@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CBS,EAL,GGDEF HSJS1_k127_2286289_3 1123073.KB899242_gene1378 1.218e-11 76.0 2DEWH@1|root,2ZPJ0@2|Bacteria,1P5UM@1224|Proteobacteria,1ST8K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2286289_6 946362.XP_004992043.1 1.71e-05 57.0 COG4886@1|root,KOG1306@1|root,KOG3594@1|root,KOG1306@2759|Eukaryota,KOG3594@2759|Eukaryota,KOG4237@2759|Eukaryota,38E30@33154|Opisthokonta 33154|Opisthokonta PT maintenance of animal organ identity GPR98 GO:0001654,GO:0001754,GO:0001894,GO:0001895,GO:0002139,GO:0002141,GO:0002142,GO:0003008,GO:0003674,GO:0004888,GO:0004930,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005929,GO:0007154,GO:0007155,GO:0007165,GO:0007186,GO:0007275,GO:0007399,GO:0007423,GO:0007600,GO:0007601,GO:0007605,GO:0008092,GO:0008104,GO:0008150,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009887,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010646,GO:0010647,GO:0010738,GO:0010739,GO:0016020,GO:0016021,GO:0016043,GO:0017022,GO:0022008,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0031224,GO:0032391,GO:0032420,GO:0032421,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0035869,GO:0038023,GO:0042221,GO:0042461,GO:0042462,GO:0042490,GO:0042592,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0043226,GO:0043235,GO:0043583,GO:0044422,GO:0044424,GO:0044425,GO:0044441,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0045184,GO:0045202,GO:0045494,GO:0045595,GO:0045596,GO:0046530,GO:0046872,GO:0048468,GO:0048471,GO:0048496,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048666,GO:0048699,GO:0048731,GO:0048839,GO:0048856,GO:0048869,GO:0048871,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050896,GO:0050906,GO:0050910,GO:0050953,GO:0050954,GO:0050974,GO:0050982,GO:0051093,GO:0051179,GO:0051234,GO:0051592,GO:0051606,GO:0051716,GO:0060089,GO:0060113,GO:0060119,GO:0060122,GO:0060249,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071277,GO:0071840,GO:0071944,GO:0090596,GO:0097458,GO:0097730,GO:0097731,GO:0097733,GO:0098590,GO:0098609,GO:0098858,GO:0098862,GO:0120025,GO:0120036,GO:0120038,GO:1902531,GO:1902533,GO:1990075,GO:1990696 - ko:K18263 - - - - ko00000,ko03036,ko04147 2.A.19.3.6 - - 7tm_2,Calx-beta,EPTP,GPS,Laminin_G_3 HSJS1_k127_2286289_5 111780.Sta7437_1574 7.902e-07 62.0 COG3794@1|root,COG3794@2|Bacteria,1G6Z2@1117|Cyanobacteria,3VK0S@52604|Pleurocapsales 1117|Cyanobacteria C Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I petE - - ko:K02638 ko00195,map00195 - - - ko00000,ko00001,ko00194 - - - Copper-bind HSJS1_k127_2286289_1 1122603.ATVI01000012_gene1134 5.881e-34 149.0 COG1404@1|root,COG2373@1|root,COG1404@2|Bacteria,COG2373@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X484@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the peptidase S8 family - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 HSJS1_k127_2295607_0 481448.Minf_1951 7.146e-152 486.0 COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,37GA2@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 HSJS1_k127_2295607_2 1156937.MFUM_700068 6.264e-66 230.0 COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia C Cytochrome c oxidase subunit III cyoC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 HSJS1_k127_2295607_5 1242864.D187_000699 0.000128 53.0 2DR0H@1|root,339NS@2|Bacteria 2|Bacteria S TIGRFAM Caa(3)-type oxidase, subunit IV - - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - COX4_pro HSJS1_k127_2295607_1 481448.Minf_1944 6.004e-73 254.0 COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia,37G6Y@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia C Cytochrome C oxidase subunit II, periplasmic domain - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 HSJS1_k127_2295607_3 526227.Mesil_2489 5.347e-17 88.0 COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH HSJS1_k127_231394_1 1121405.dsmv_3723 3.41e-40 166.0 COG0535@1|root,COG0535@2|Bacteria,1QQ55@1224|Proteobacteria,42YIG@68525|delta/epsilon subdivisions,2WU3K@28221|Deltaproteobacteria 28221|Deltaproteobacteria C SMART Elongator protein 3 MiaB NifB - - - ko:K22226 - - - - ko00000 - - - Fer4_12,Radical_SAM HSJS1_k127_231394_2 985665.HPL003_26400 9.855e-06 57.0 2DJVE@1|root,307G4@2|Bacteria,1U1MD@1239|Firmicutes,4IB3T@91061|Bacilli,273NG@186822|Paenibacillaceae 91061|Bacilli S Coenzyme PQQ synthesis protein D (PqqD) - - - - - - - - - - - - PqqD HSJS1_k127_231394_0 1337936.IJ00_01345 7.497e-41 166.0 COG0438@1|root,COG0438@2|Bacteria,1G3FI@1117|Cyanobacteria,1HN07@1161|Nostocales 1117|Cyanobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_2316421_0 931626.Awo_c17330 4.383e-05 52.0 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,25X33@186806|Eubacteriaceae 186801|Clostridia K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3 HSJS1_k127_2325461_0 1499967.BAYZ01000182_gene4458 1.78e-80 271.0 COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria 2|Bacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0273,iECDH10B_1368.ECDH10B_0261,iECS88_1305.ECS88_4841,iHN637.CLJU_RS12430,iJO1366.b0273,iJR904.b0273,iY75_1357.Y75_RS01410 OTCace,OTCace_N HSJS1_k127_2325461_1 237368.SCABRO_02413 7.59e-63 231.0 29MQ2@1|root,308MT@2|Bacteria,2J179@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_2325461_3 272557.APE_1882.1 4.984e-12 80.0 arCOG00372@1|root,arCOG00372@2157|Archaea 2157|Archaea P cobalamin transport - - - - - - - - - - - - - HSJS1_k127_2325461_5 869210.Marky_0468 1.519e-09 71.0 COG1502@1|root,COG1502@2|Bacteria,1WJ7I@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc_2 HSJS1_k127_2325461_2 391625.PPSIR1_36492 8.254e-13 81.0 COG4935@1|root,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - DUF4215,P_proprotein HSJS1_k127_2327749_1 318167.Sfri_0463 2.973e-15 86.0 COG0526@1|root,COG0526@2|Bacteria,1NAHI@1224|Proteobacteria,1SCND@1236|Gammaproteobacteria,2QB1H@267890|Shewanellaceae 1236|Gammaproteobacteria CO Thioredoxin - - - - - - - - - - - - Thioredoxin,Thioredoxin_9 HSJS1_k127_2327749_0 869210.Marky_0170 2.286e-22 98.0 COG0530@1|root,COG0530@2|Bacteria,1WJ9P@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex HSJS1_k127_232858_0 748247.AZKH_4240 2.451e-70 245.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KU97@206389|Rhodocyclales 206389|Rhodocyclales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_232858_2 1122176.KB903543_gene456 5.945e-15 87.0 COG1520@1|root,COG3386@1|root,COG1520@2|Bacteria,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes 976|Bacteroidetes G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - HSJS1_k127_232858_1 1340493.JNIF01000003_gene2976 6.208e-19 100.0 COG0596@1|root,COG2976@1|root,COG0596@2|Bacteria,COG2976@2|Bacteria 2|Bacteria CO Protein conserved in bacteria - - - - - - - - - - - - Abhydrolase_1,Beta-lactamase,TPR_2,TPR_21,TPR_8 HSJS1_k127_2329716_4 469383.Cwoe_0217 2.257e-10 72.0 COG3832@1|root,COG3832@2|Bacteria,2HQ66@201174|Actinobacteria 201174|Actinobacteria S Pfam Activator of Hsp90 ATPase - - - - - - - - - - - - AHSA1 HSJS1_k127_2329716_3 34007.IT40_20425 5.125e-33 140.0 COG0640@1|root,COG0640@2|Bacteria,1RCIH@1224|Proteobacteria,2U6EZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_20 HSJS1_k127_2329716_0 1117647.M5M_03465 1.87e-85 292.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1J4VV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D recombinase XerD xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase HSJS1_k127_2329716_2 765912.Thimo_0654 2.307e-38 152.0 COG0741@1|root,COG0790@1|root,COG0741@2|Bacteria,COG0790@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1WZ32@135613|Chromatiales 135613|Chromatiales M Soluble lytic murein transglycosylase-like protein - - - - - - - - - - - - SLT,Sel1 HSJS1_k127_2329716_1 1121439.dsat_0775 1.441e-41 175.0 COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2M7Z5@213115|Desulfovibrionales 28221|Deltaproteobacteria KT SMART protein phosphatase 2C domain protein - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Cache_3-Cache_2,HAMP,SpoIIE,dCache_1,dCache_2 HSJS1_k127_2329716_5 1122611.KB903969_gene2398 0.0002032 51.0 COG1592@1|root,COG1592@2|Bacteria,2I8N0@201174|Actinobacteria,4EMSQ@85012|Streptosporangiales 201174|Actinobacteria C Rubrerythrin - - - - - - - - - - - - Rubrerythrin HSJS1_k127_2336547_1 1172188.KB911823_gene547 1.29e-54 203.0 COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4FFRP@85021|Intrasporangiaceae 201174|Actinobacteria I Diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat HSJS1_k127_2336547_4 243924.LT42_16385 1.312e-12 75.0 COG0695@1|root,COG0695@2|Bacteria,1N6ZT@1224|Proteobacteria,1SD1U@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutaredoxin nrdH - - - - - - - - - - - Glutaredoxin HSJS1_k127_2336547_2 1354300.AUQY01000005_gene295 1.221e-45 181.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia 186801|Clostridia S TRAP transporter solute receptor, TAXI family bcsP - - ko:K07080 - - - - ko00000 - - - NMT1_3 HSJS1_k127_2336547_0 1449126.JQKL01000012_gene3462 3.244e-102 358.0 COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,26A4B@186813|unclassified Clostridiales 186801|Clostridia S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DUF3394,DctM HSJS1_k127_2336547_3 1961.JOAK01000039_gene4358 5.845e-39 149.0 COG1487@1|root,COG1487@2|Bacteria,2IJUM@201174|Actinobacteria 201174|Actinobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - - - - - - - - - - PIN HSJS1_k127_2337910_3 292459.STH1612 5.194e-44 166.0 COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes 1239|Firmicutes H May be involved in the biosynthesis of molybdopterin moaB - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth HSJS1_k127_2337910_6 457398.HMPREF0326_00717 0.000287 53.0 COG2261@1|root,COG2261@2|Bacteria,1NGEB@1224|Proteobacteria,42VUV@68525|delta/epsilon subdivisions,2WS8X@28221|Deltaproteobacteria,2MCW3@213115|Desulfovibrionales 28221|Deltaproteobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc HSJS1_k127_2337910_1 1242864.D187_010239 2.254e-76 273.0 COG4403@1|root,COG4403@2|Bacteria,1R8AJ@1224|Proteobacteria,43EZ6@68525|delta/epsilon subdivisions,2WYJK@28221|Deltaproteobacteria,2YZ2R@29|Myxococcales 28221|Deltaproteobacteria V Lanthionine synthetase C-like protein - - - ko:K20484 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - LANC_like HSJS1_k127_2337910_2 289376.THEYE_A0673 2.853e-50 188.0 COG0302@1|root,COG0302@2|Bacteria,3J0Q0@40117|Nitrospirae 40117|Nitrospirae F GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI HSJS1_k127_2337910_4 926566.Terro_1749 3.133e-14 85.0 COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia 204432|Acidobacteriia KT Peptidase M56 - - - - - - - - - - - - - HSJS1_k127_2337910_0 215803.DB30_1749 1.746e-116 386.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales 28221|Deltaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C HSJS1_k127_234394_3 398720.MED217_05662 9.759e-09 62.0 28XWV@1|root,2ZJT0@2|Bacteria,4P9A9@976|Bacteroidetes,1IBUT@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - HSJS1_k127_234394_0 761193.Runsl_4734 4.21e-32 141.0 COG2755@1|root,COG2755@2|Bacteria,4PM80@976|Bacteroidetes,47SH2@768503|Cytophagia 976|Bacteroidetes E lipolytic protein G-D-S-L family - - - - - - - - - - - - - HSJS1_k127_234394_1 946077.W5A_11059 8.178e-29 119.0 COG3422@1|root,COG3422@2|Bacteria,4NS9J@976|Bacteroidetes,1I40P@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF1508) - - - ko:K09946 - - - - ko00000 - - - DUF1508 HSJS1_k127_2345845_1 269799.Gmet_1174 5.18e-70 267.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales 28221|Deltaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge HSJS1_k127_2345845_4 1304885.AUEY01000033_gene1895 1.948e-05 57.0 2EC3H@1|root,3362D@2|Bacteria,1NDXP@1224|Proteobacteria,42WQJ@68525|delta/epsilon subdivisions,2WRNF@28221|Deltaproteobacteria,2MKWZ@213118|Desulfobacterales 28221|Deltaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ HSJS1_k127_2345845_2 1121920.AUAU01000030_gene2721 3.761e-35 154.0 COG0515@1|root,COG0515@2|Bacteria 1121920.AUAU01000030_gene2721|- KLT protein kinase activity - - - - - - - - - - - - - HSJS1_k127_2345845_0 1128421.JAGA01000001_gene2337 2.658e-77 267.0 COG0572@1|root,COG0572@2|Bacteria,2NPKT@2323|unclassified Bacteria 2|Bacteria F Phosphoribulokinase / Uridine kinase family udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 ko:K00855,ko:K00876 ko00240,ko00710,ko00983,ko01100,ko01120,ko01200,map00240,map00710,map00983,map01100,map01120,map01200 M00165,M00166 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01523,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0893 PRK HSJS1_k127_2345845_3 589865.DaAHT2_1602 1.918e-18 85.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,42T7F@68525|delta/epsilon subdivisions,2WP8W@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS HSJS1_k127_2349170_0 1089547.KB913013_gene2262 1.155e-51 196.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 HSJS1_k127_2349170_2 331678.Cphamn1_0701 6.315e-41 172.0 COG0683@1|root,COG0683@2|Bacteria 2|Bacteria E ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 HSJS1_k127_2349170_1 926550.CLDAP_18850 1.221e-43 166.0 COG1448@1|root,COG1448@2|Bacteria 2|Bacteria E Aminotransferase aspC GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iPC815.YPO1410,iSFxv_1172.SFxv_1000 Aminotran_1_2 HSJS1_k127_235317_1 1379698.RBG1_1C00001G0858 1.734e-26 115.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C HSJS1_k127_235317_0 443144.GM21_2959 1.901e-235 744.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria 28221|Deltaproteobacteria C malic protein domain protein mdh - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic HSJS1_k127_2355135_4 530564.Psta_2542 4.61e-56 214.0 COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes 203682|Planctomycetes S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_2355135_3 439235.Dalk_0190 5.991e-60 237.0 COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Sulfatase - - - - - - - - - - - - Sulfatase HSJS1_k127_2355135_0 526227.Mesil_0601 6.541e-196 624.0 COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 HSJS1_k127_2355135_2 1403819.BATR01000092_gene2754 9.331e-114 381.0 COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia 74201|Verrucomicrobia S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC HSJS1_k127_2355135_1 1128421.JAGA01000003_gene2937 3.736e-116 379.0 COG0476@1|root,COG0476@2|Bacteria,2NPX3@2323|unclassified Bacteria 2|Bacteria H ThiF family moeB - 2.7.7.73,2.7.7.80,2.8.1.11 ko:K03148,ko:K21029,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF HSJS1_k127_2363402_0 404589.Anae109_0939 1.013e-172 559.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales 28221|Deltaproteobacteria L ATP dependent DNA ligase domain protein - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N HSJS1_k127_2363402_1 404589.Anae109_0938 3.02e-82 282.0 COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales 28221|Deltaproteobacteria L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku - - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku HSJS1_k127_2363402_2 404589.Anae109_0937 1.479e-60 219.0 COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11 HSJS1_k127_2364437_3 1121271.AUCM01000015_gene2533 1.634e-34 143.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2U361@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - DUF971,ParA HSJS1_k127_2364437_5 652103.Rpdx1_4701 9.669e-30 119.0 COG1598@1|root,COG1598@2|Bacteria,1NBIX@1224|Proteobacteria,2UHJC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox HSJS1_k127_2364437_8 864051.BurJ1DRAFT_1863 4.141e-15 81.0 COG1724@1|root,COG1724@2|Bacteria 2|Bacteria N mRNA binding - - - ko:K07339 - - - - ko00000,ko01000,ko02048 - - - HicA_toxin HSJS1_k127_2364437_0 247490.KSU1_C1314 2.325e-100 345.0 COG0535@1|root,COG0535@2|Bacteria,2J2KS@203682|Planctomycetes 203682|Planctomycetes S Proto-chlorophyllide reductase 57 kD subunit - - - - - - - - - - - - PCP_red,Radical_SAM,SPASM HSJS1_k127_2364437_2 1267535.KB906767_gene4941 5.484e-37 147.0 COG1595@1|root,COG1595@2|Bacteria,3Y5K8@57723|Acidobacteria 57723|Acidobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_2364437_4 870187.Thini_0382 1.501e-32 130.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales 72273|Thiotrichales L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 HSJS1_k127_2364437_6 1121441.AUCX01000005_gene1290 3.033e-28 123.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria 1224|Proteobacteria M PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - FGE-sulfatase,PEGA,Peptidase_C14 HSJS1_k127_2364437_1 869210.Marky_0500 1.556e-68 251.0 COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH HSJS1_k127_236657_3 765420.OSCT_1878 8.153e-43 158.0 COG4637@1|root,COG4637@2|Bacteria 2|Bacteria L Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_15,AAA_21 HSJS1_k127_236657_2 113355.CM001775_gene1163 2.329e-63 227.0 2DHAE@1|root,2ZYZ6@2|Bacteria,1G71I@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF4276) - - - - - - - - - - - - DUF4276 HSJS1_k127_236657_1 324602.Caur_2847 4.749e-68 243.0 COG1015@1|root,COG1015@2|Bacteria,2GA8G@200795|Chloroflexi,375QI@32061|Chloroflexia 32061|Chloroflexia G PFAM metalloenzyme domain protein - - - - - - - - - - - - Metalloenzyme HSJS1_k127_236657_0 247490.KSU1_C0522 1.162e-88 305.0 COG1131@1|root,COG1131@2|Bacteria,2IX20@203682|Planctomycetes 203682|Planctomycetes V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_236657_4 391625.PPSIR1_10175 7.902e-37 147.0 COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2Z340@29|Myxococcales 28221|Deltaproteobacteria N ABC-type uncharacterized transport system - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux HSJS1_k127_236679_2 497964.CfE428DRAFT_0769 1.495e-64 232.0 COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia 74201|Verrucomicrobia S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_236679_3 518766.Rmar_0718 2.038e-45 176.0 COG2153@1|root,COG2153@2|Bacteria,4NT5M@976|Bacteroidetes,1FJFY@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 HSJS1_k127_236679_1 880073.Calab_1643 8.723e-129 424.0 COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria 2|Bacteria G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27,3.2.1.68 ko:K00975,ko:K01214 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948,R09995,R11261 RC00002 ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 iJN678.agp,iSbBS512_1146.agp NTP_transferase HSJS1_k127_236679_0 880073.Calab_3584 3.24e-139 465.0 COG0297@1|root,COG0297@2|Bacteria,2NQKG@2323|unclassified Bacteria 2|Bacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 HSJS1_k127_2368071_3 561175.KB894093_gene3072 9.262e-23 107.0 COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg HSJS1_k127_2368071_4 227882.SAV_2438 1.05e-21 109.0 COG2197@1|root,COG2197@2|Bacteria,2GNAU@201174|Actinobacteria 201174|Actinobacteria T response regulator - - - - - - - - - - - - GerE,Response_reg HSJS1_k127_2368071_2 401526.TcarDRAFT_1783 1.17e-28 119.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4H5BU@909932|Negativicutes 909932|Negativicutes F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 HSJS1_k127_2368071_0 498761.HM1_1471 2.112e-191 606.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,25F02@186801|Clostridia 186801|Clostridia C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh HSJS1_k127_2368071_1 485913.Krac_12114 8.721e-112 368.0 COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi 200795|Chloroflexi C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N HSJS1_k127_237731_1 1038867.AXAY01000023_gene4617 1.08e-55 201.0 COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2U13E@28211|Alphaproteobacteria,3JXB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major intrinsic protein - - - - - - - - - - - - MIP HSJS1_k127_237731_0 1242864.D187_010056 5.592e-119 402.0 COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,43C6E@68525|delta/epsilon subdivisions,2WTIV@28221|Deltaproteobacteria,2YZ25@29|Myxococcales 28221|Deltaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N HSJS1_k127_2386769_3 927677.ALVU02000004_gene4743 3.261e-26 110.0 COG2303@1|root,COG2303@2|Bacteria,1FZYZ@1117|Cyanobacteria 1117|Cyanobacteria E Belongs to the GMC oxidoreductase family - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N HSJS1_k127_2386769_4 1519464.HY22_08955 1.885e-05 53.0 COG2214@1|root,COG2214@2|Bacteria,1FFIH@1090|Chlorobi 1090|Chlorobi O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ HSJS1_k127_2386769_1 375286.mma_2596 5.235e-75 259.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae 28216|Betaproteobacteria H Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA HSJS1_k127_2386769_0 861299.J421_0704 1.415e-320 1002.0 COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes 142182|Gemmatimonadetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_2386769_2 859657.RPSI07_mp0268 1.114e-31 136.0 2ECD7@1|root,336BF@2|Bacteria,1NWNW@1224|Proteobacteria,2WD57@28216|Betaproteobacteria,1K9E3@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2400892_3 667121.ET1_12_01220 9.501e-05 55.0 COG1131@1|root,COG1131@2|Bacteria,1R934@1224|Proteobacteria,1S8BY@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter - - - - - - - - - - - - - HSJS1_k127_2400892_1 391625.PPSIR1_39300 7.207e-78 278.0 COG3361@1|root,COG3361@2|Bacteria,1Q2C9@1224|Proteobacteria,437YP@68525|delta/epsilon subdivisions,2X38K@28221|Deltaproteobacteria,2YUU6@29|Myxococcales 28221|Deltaproteobacteria S Uncharacterized conserved protein (COG2071) - - - ko:K09166 - - - - ko00000 - - - DUF2071 HSJS1_k127_2400892_0 941449.dsx2_1144 7.853e-169 556.0 COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2MB2B@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase,QRPTase_C HSJS1_k127_2400892_2 1122134.KB893650_gene1188 1.684e-51 196.0 COG1629@1|root,COG4771@2|Bacteria,1RAXV@1224|Proteobacteria,1S3M5@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor - - - ko:K02014,ko:K16087 - - - - ko00000,ko02000 1.B.14,1.B.14.2 - - Plug,TonB_dep_Rec HSJS1_k127_2402562_0 243231.GSU0456 5.808e-78 292.0 COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,430XH@68525|delta/epsilon subdivisions,2WW53@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein export membrane protein - - - ko:K07003 - - - - ko00000 - - - MMPL HSJS1_k127_2402562_1 888727.HMPREF9092_0104 3.123e-26 113.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3WDAX@538999|Clostridiales incertae sedis 186801|Clostridia I CDP-alcohol phosphatidyltransferase pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf HSJS1_k127_2408348_0 861299.J421_4059 6.267e-149 497.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_2408348_2 665571.STHERM_c11820 1.069e-65 235.0 COG1028@1|root,COG1028@2|Bacteria 665571.STHERM_c11820|- IQ oxidoreductase activity, acting on CH-OH group of donors - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - - HSJS1_k127_2408348_1 1121430.JMLG01000002_gene1080 7.54e-104 347.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae 186801|Clostridia I PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N HSJS1_k127_2408348_4 448385.sce0093 3.218e-41 161.0 COG0783@1|root,COG0783@2|Bacteria 2|Bacteria P Belongs to the Dps family - - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin HSJS1_k127_2408348_3 682795.AciX8_1275 8.804e-44 182.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - AhpC-TSA,Redoxin,Thioredoxin,Thioredoxin_9 HSJS1_k127_2417159_2 946235.CAER01000002_gene692 2.22e-08 68.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,23J7J@182709|Oceanobacillus 91061|Bacilli O CarboxypepD_reg-like domain bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 HSJS1_k127_2417159_1 1278073.MYSTI_02559 2.425e-51 207.0 COG3266@1|root,COG3266@2|Bacteria,1QXUY@1224|Proteobacteria,43C7M@68525|delta/epsilon subdivisions,2X7HX@28221|Deltaproteobacteria,2Z10E@29|Myxococcales 28221|Deltaproteobacteria E Calcium-binding EGF domain - - - - - - - - - - - - DUF4215,EGF_CA,Stig1 HSJS1_k127_2417159_0 861299.J421_4025 5.6e-81 279.0 COG0644@1|root,COG0644@2|Bacteria 2|Bacteria C geranylgeranyl reductase activity prnC - 1.14.19.49 ko:K14257 ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130 M00790,M00823 R05456,R11106,R11478 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase HSJS1_k127_2419956_1 903818.KI912268_gene2476 2.151e-55 206.0 COG0436@1|root,COG0436@2|Bacteria 2|Bacteria E Aminotransferase bamJ - - - - - - - - - - iSB619.SA_RS10050 Aminotran_1_2 HSJS1_k127_2419956_2 84531.JMTZ01000039_gene548 2.531e-39 168.0 COG0739@1|root,COG0739@2|Bacteria,1R8E7@1224|Proteobacteria,1RZDF@1236|Gammaproteobacteria,1X9EG@135614|Xanthomonadales 135614|Xanthomonadales M BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M23,Peptidase_M56 HSJS1_k127_2419956_3 394221.Mmar10_2142 6.039e-23 104.0 COG3682@1|root,COG3682@2|Bacteria,1MZU3@1224|Proteobacteria,2UIN1@28211|Alphaproteobacteria,43Y9J@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Penicillinase_R HSJS1_k127_2419956_0 1173020.Cha6605_2607 1.826e-91 312.0 COG1262@1|root,COG1262@2|Bacteria,1G0FF@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - DinB_2,FGE-sulfatase HSJS1_k127_2421579_11 644282.Deba_1207 3.606e-22 102.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA HSJS1_k127_2421579_2 572479.Hprae_2058 1.651e-123 416.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WADX@53433|Halanaerobiales 186801|Clostridia J PFAM tRNA synthetases class I (W and Y) trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b HSJS1_k127_2421579_7 1487953.JMKF01000004_gene680 3.617e-33 145.0 COG2931@1|root,COG2931@2|Bacteria,1G02E@1117|Cyanobacteria,1H9TQ@1150|Oscillatoriales 1117|Cyanobacteria Q Hemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - Calx-beta,HemolysinCabind HSJS1_k127_2421579_12 497964.CfE428DRAFT_3727 1.108e-14 82.0 2FH6M@1|root,34912@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4203) - - - - - - - - - - - - DUF4203 HSJS1_k127_2421579_6 290397.Adeh_3950 2.147e-37 150.0 COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Thioredoxin - - - - - - - - - - - - SurA_N_3,Thioredoxin_4 HSJS1_k127_2421579_1 502025.Hoch_4261 9.88e-176 563.0 COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria 1224|Proteobacteria S C4-dicarboxylate anaerobic - - - - - - - - - - - - DcuC HSJS1_k127_2421579_4 502025.Hoch_6686 1.24e-91 317.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria 28221|Deltaproteobacteria J HRDC domain protein rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC HSJS1_k127_2421579_3 1254432.SCE1572_17000 5.768e-123 404.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2WMFU@28221|Deltaproteobacteria 28221|Deltaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA - - - - - - - - - - - APH HSJS1_k127_2421579_5 382464.ABSI01000016_gene745 5.109e-40 157.0 COG2259@1|root,COG2259@2|Bacteria,46T2M@74201|Verrucomicrobia,2IUPP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX HSJS1_k127_2421579_13 1392498.JQLH01000001_gene2894 1.462e-11 73.0 COG5661@1|root,COG5661@2|Bacteria,4NW11@976|Bacteroidetes,1I32R@117743|Flavobacteriia,2PHFG@252356|Maribacter 976|Bacteroidetes O secreted Zn-dependent protease - - - - - - - - - - - - DUF922 HSJS1_k127_2421579_8 1454004.AW11_00880 5.203e-29 122.0 2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,2VW4Y@28216|Betaproteobacteria 28216|Betaproteobacteria S CcdB protein - - - ko:K19163 - - - - ko00000,ko02048 - - - CcdB HSJS1_k127_2421579_9 1226994.AMZB01000132_gene4890 5.599e-27 113.0 COG5302@1|root,COG5302@2|Bacteria,1NIFA@1224|Proteobacteria,1TB7Q@1236|Gammaproteobacteria,1YH2K@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Post-segregation antitoxin CcdA - - - ko:K19164 - - - - ko00000,ko02048 - - - CcdA HSJS1_k127_2421579_0 1121124.JNIX01000016_gene2071 5.335e-210 668.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2KG4I@204458|Caulobacterales 204458|Caulobacterales QU Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 HSJS1_k127_2424328_2 517418.Ctha_1393 7.576e-43 165.0 COG0457@1|root,COG0457@2|Bacteria,1FD7Y@1090|Chlorobi 517418.Ctha_1393|- K PFAM TPR repeat-containing protein - - - - - - - - - - - - - HSJS1_k127_2424328_0 566466.NOR53_938 1.729e-223 702.0 COG1228@1|root,COG1228@2|Bacteria,1R500@1224|Proteobacteria,1RZG5@1236|Gammaproteobacteria,1J7ZB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 HSJS1_k127_2424328_1 1267533.KB906733_gene3151 1.417e-82 301.0 2CDI3@1|root,3416N@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2424328_3 416348.Hlac_2600 9.422e-13 74.0 COG1917@1|root,arCOG02994@2157|Archaea,2XY1A@28890|Euryarchaeota,23WE5@183963|Halobacteria 183963|Halobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 HSJS1_k127_2425278_4 1173028.ANKO01000124_gene2796 6.255e-14 74.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1FZWQ@1117|Cyanobacteria,1HHTJ@1150|Oscillatoriales 1117|Cyanobacteria KLT PFAM Protein kinase - - - - - - - - - - - - FGE-sulfatase,Pkinase HSJS1_k127_2425278_1 391587.KAOT1_01360 5.299e-60 218.0 COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes,1HXNU@117743|Flavobacteriia 976|Bacteroidetes K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI HSJS1_k127_2425278_3 575540.Isop_1065 6.01e-28 126.0 COG3483@1|root,COG3483@2|Bacteria,2J412@203682|Planctomycetes 203682|Planctomycetes E Tryptophan 2,3-dioxygenase - - 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase HSJS1_k127_2425278_2 935863.AWZR01000012_gene2543 1.838e-38 160.0 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,1X433@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 HSJS1_k127_2425278_0 550540.Fbal_2494 1.478e-158 533.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mdtB - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_2431851_0 221288.JH992901_gene1062 1.582e-80 279.0 COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria,1JH5Z@1189|Stigonemataceae 1117|Cyanobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 HSJS1_k127_2431851_1 1121930.AQXG01000004_gene2853 3.181e-66 244.0 28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,1IQ98@117747|Sphingobacteriia 976|Bacteroidetes S S1 P1 nuclease - - - - - - - - - - - - S1-P1_nuclease HSJS1_k127_2431851_2 1089550.ATTH01000001_gene721 7.733e-36 143.0 COG0607@1|root,COG0607@2|Bacteria,4NQ61@976|Bacteroidetes,1FK3N@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese HSJS1_k127_2436210_2 1089550.ATTH01000001_gene1485 2.353e-53 191.0 COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes 976|Bacteroidetes M Pfam Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_2436210_3 1121918.ARWE01000001_gene3596 5.483e-33 139.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42WIA@68525|delta/epsilon subdivisions,2WS9S@28221|Deltaproteobacteria,43VMM@69541|Desulfuromonadales 28221|Deltaproteobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 HSJS1_k127_2436210_4 1123257.AUFV01000006_gene386 5.282e-15 89.0 COG2133@1|root,COG2133@2|Bacteria,1R0C0@1224|Proteobacteria 1224|Proteobacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - GSDH HSJS1_k127_2436210_1 1121405.dsmv_0576 1.022e-54 209.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PS7@68525|delta/epsilon subdivisions,2WMMC@28221|Deltaproteobacteria,2MKY8@213118|Desulfobacterales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 HSJS1_k127_2436210_0 690850.Desaf_3621 2.574e-166 539.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_2438239_1 991905.SL003B_4075 1.971e-105 357.0 COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria 1224|Proteobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_23,HTH_38,HTH_7,rve HSJS1_k127_2438239_2 1123229.AUBC01000040_gene3836 3.59e-93 330.0 COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TS16@28211|Alphaproteobacteria,3JSGF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L IstB-like ATP binding protein - - - - - - - - - - - - IstB_IS21 HSJS1_k127_2438239_0 686340.Metal_3883 1.478e-105 349.0 COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - Transposase_mut HSJS1_k127_2439914_1 269799.Gmet_1137 3.237e-106 351.0 COG3500@1|root,COG3500@2|Bacteria,1QK0F@1224|Proteobacteria,42T0N@68525|delta/epsilon subdivisions,2WPW1@28221|Deltaproteobacteria,43VVG@69541|Desulfuromonadales 28221|Deltaproteobacteria S Late control gene D protein - - - - - - - - - - - - - HSJS1_k127_2439914_3 269799.Gmet_1136 3.136e-29 130.0 COG1652@1|root,COG1652@2|Bacteria,1NF3W@1224|Proteobacteria,42XK4@68525|delta/epsilon subdivisions,2WSWJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S LysM domain - - - - - - - - - - - - - HSJS1_k127_2439914_2 269799.Gmet_1135 4.734e-98 325.0 2CI52@1|root,2ZC5H@2|Bacteria,1R9WI@1224|Proteobacteria,42SVH@68525|delta/epsilon subdivisions,2WPSB@28221|Deltaproteobacteria,43VVW@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2439914_0 269799.Gmet_1133 9.105e-137 440.0 COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WJFR@28221|Deltaproteobacteria,43UUT@69541|Desulfuromonadales 28221|Deltaproteobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA HSJS1_k127_2440042_1 1108045.GORHZ_073_00030 2.668e-50 198.0 COG0457@1|root,COG2885@1|root,COG2931@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,COG2931@2|Bacteria,2IBAR@201174|Actinobacteria 201174|Actinobacteria M chlorophyll binding - - - - - - - - - - - - - HSJS1_k127_2440042_7 314271.RB2654_04471 2.833e-10 73.0 COG2931@1|root,COG3209@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria 1224|Proteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - HemolysinCabind,Hint_2 HSJS1_k127_2440042_4 745310.G432_11675 4.172e-16 88.0 29AT2@1|root,2ZXSJ@2|Bacteria,1NQI3@1224|Proteobacteria,2UPU5@28211|Alphaproteobacteria,2K59W@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - HSJS1_k127_2440042_5 694429.Pyrfu_1439 5.47e-13 82.0 COG2524@1|root,arCOG00610@2157|Archaea,2XPSP@28889|Crenarchaeota 28889|Crenarchaeota K signal transduction protein with CBS domains - - - ko:K07744 - - - - ko00000 - - - CBS,HrcA_DNA-bdg HSJS1_k127_2440042_0 1340493.JNIF01000003_gene3840 1.209e-91 325.0 COG1252@1|root,COG1252@2|Bacteria,3Y308@57723|Acidobacteria 2|Bacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - CBS,Pyr_redox_2,cNMP_binding HSJS1_k127_2440042_2 688269.Theth_1298 1.377e-17 83.0 COG1598@1|root,COG1598@2|Bacteria,2GDGG@200918|Thermotogae 200918|Thermotogae S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - - HSJS1_k127_2440042_3 644968.DFW101_1583 5.428e-17 93.0 COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales 28221|Deltaproteobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 HSJS1_k127_2440042_6 1047013.AQSP01000088_gene1634 5.768e-13 83.0 COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NR7I@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - DUF560,Dynamin_N,Peptidase_M48,TPR_19,TPR_8 HSJS1_k127_2440228_0 880073.Calab_3349 2.888e-147 479.0 COG0457@1|root,COG0457@2|Bacteria 880073.Calab_3349|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_2440228_1 290397.Adeh_1998 3.761e-47 189.0 COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA_3 HSJS1_k127_2442733_1 867903.ThesuDRAFT_00516 6.216e-140 464.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia,3WCUA@538999|Clostridiales incertae sedis 186801|Clostridia E Aminotransferase class-III gabT - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - iHN637.CLJU_RS10045 Aminotran_3 HSJS1_k127_2442733_0 1231241.Mc24_01329 7.033e-147 492.0 COG0495@1|root,COG0495@2|Bacteria,2GC3Z@200918|Thermotogae 200918|Thermotogae J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 HSJS1_k127_2444747_0 926550.CLDAP_31550 2.006e-171 557.0 COG4579@1|root,COG4579@2|Bacteria 2|Bacteria F [isocitrate dehydrogenase (NADP+)] phosphatase activity aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK HSJS1_k127_2444747_2 502025.Hoch_4010 1.144e-32 130.0 2AGM5@1|root,316UC@2|Bacteria,1PY0S@1224|Proteobacteria,43509@68525|delta/epsilon subdivisions,2WZB6@28221|Deltaproteobacteria,2Z1RE@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2444747_1 1089550.ATTH01000001_gene1255 1.486e-169 551.0 COG0728@1|root,COG0728@2|Bacteria,4PF1K@976|Bacteroidetes,1FK01@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Polysaccharide biosynthesis protein - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN HSJS1_k127_2444747_3 1245471.PCA10_14030 4.518e-17 87.0 COG2132@1|root,COG2132@2|Bacteria,1QZ1I@1224|Proteobacteria,1S18S@1236|Gammaproteobacteria,1YI4W@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q Multicopper oxidase - - 1.16.3.3 ko:K22350 - - - - ko00000,ko01000 - - - Cu-oxidase_2 HSJS1_k127_2445824_1 768671.ThimaDRAFT_2935 3.881e-51 187.0 COG4636@1|root,COG4636@2|Bacteria,1RGJD@1224|Proteobacteria,1S5E9@1236|Gammaproteobacteria,1WYD0@135613|Chromatiales 2|Bacteria S Putative restriction endonuclease - - - - - - - - - - - - Uma2 HSJS1_k127_2445824_3 1382306.JNIM01000001_gene4208 3.985e-06 59.0 2EW20@1|root,33PF9@2|Bacteria 2|Bacteria S Putative zinc-finger - - - - - - - - - - - - zf-HC2 HSJS1_k127_2445824_2 644966.Tmar_0414 3.327e-37 149.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WDGI@538999|Clostridiales incertae sedis 186801|Clostridia K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_2445824_0 1121920.AUAU01000004_gene773 1.196e-56 208.0 COG0860@1|root,COG0860@2|Bacteria 2|Bacteria M N-Acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448,ko:K02172 ko01501,ko01503,map01501,map01503 M00627,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036 - - - Amidase_3,Cu_amine_oxidN1 HSJS1_k127_2449829_2 266117.Rxyl_1135 6.692e-16 86.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi HSJS1_k127_2449829_0 756272.Plabr_0552 1.543e-140 460.0 COG0624@1|root,COG0624@2|Bacteria,2IXPJ@203682|Planctomycetes 203682|Planctomycetes E ArgE DapE Acy1 family protein - - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 HSJS1_k127_2449829_1 926569.ANT_07800 6.502e-22 102.0 COG1437@1|root,COG1437@2|Bacteria,2G9FW@200795|Chloroflexi 200795|Chloroflexi F CYTH domain - - 4.6.1.1 ko:K05873 ko00230,map00230 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - CYTH HSJS1_k127_2450239_0 1121904.ARBP01000004_gene821 2.803e-86 297.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia 976|Bacteroidetes E PFAM Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 HSJS1_k127_2461325_1 234267.Acid_1303 1.554e-201 679.0 COG0515@1|root,COG2114@1|root,COG3899@1|root,COG3903@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria 2|Bacteria K ADP binding - - - - - - - - - - - - AAA_16,GerE,Guanylate_cyc,Pkinase HSJS1_k127_2461325_0 314230.DSM3645_19883 2.537e-214 678.0 COG0069@1|root,COG0069@2|Bacteria,2J28V@203682|Planctomycetes 203682|Planctomycetes E Belongs to the glutamate synthase family - - 2.1.1.21 ko:K22083 ko00680,ko01120,map00680,map01120 - R01586 RC00554 ko00000,ko00001,ko01000 - - - Glu_synthase HSJS1_k127_2461325_2 1121946.AUAX01000017_gene4921 2.136e-117 402.0 COG1032@1|root,COG1032@2|Bacteria,2HGPR@201174|Actinobacteria,4D9TA@85008|Micromonosporales 201174|Actinobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM HSJS1_k127_2461325_3 204669.Acid345_3544 3.597e-83 309.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7VQ@57723|Acidobacteria,2JNB0@204432|Acidobacteriia 204432|Acidobacteriia K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Trans_reg_C HSJS1_k127_2461325_4 502025.Hoch_1729 2.737e-16 94.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria 1224|Proteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - AAA_16,PEGA,Pkinase,TPR_12 HSJS1_k127_2462329_7 1379698.RBG1_1C00001G0806 5.782e-39 147.0 COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria 2|Bacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 HSJS1_k127_2462329_2 292459.STH804 1.296e-110 374.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 186801|Clostridia I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N HSJS1_k127_2462329_10 1121864.OMO_02244 7.458e-35 143.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,4B1MN@81852|Enterococcaceae 91061|Bacilli T Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 HSJS1_k127_2462329_6 76114.ebA5296 2.973e-53 207.0 COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales 206389|Rhodocyclales I Enoyl-CoA hydratase/isomerase dch - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 HSJS1_k127_2462329_3 1210908.HSB1_00800 6.857e-82 282.0 COG1024@1|root,arCOG00239@2157|Archaea,2XTF0@28890|Euryarchaeota,23SMM@183963|Halobacteria 183963|Halobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 HSJS1_k127_2462329_0 234267.Acid_2875 1.489e-123 407.0 COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria 57723|Acidobacteria F Aminotransferase class-V - - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 HSJS1_k127_2462329_5 338963.Pcar_2753 2.246e-57 211.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2X75V@28221|Deltaproteobacteria,43UV8@69541|Desulfuromonadales 28221|Deltaproteobacteria T HD domain - - - - - - - - - - - - HD_5 HSJS1_k127_2462329_4 290397.Adeh_0504 4.965e-64 234.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_2462329_11 1125863.JAFN01000001_gene293 1.376e-28 120.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS HSJS1_k127_2462329_9 546266.NEIMUCOT_05686 4.729e-35 150.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,2KQXV@206351|Neisseriales 206351|Neisseriales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like HSJS1_k127_2462329_1 1382359.JIAL01000001_gene654 4.009e-111 369.0 COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria,2JI5G@204432|Acidobacteriia 204432|Acidobacteriia S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 HSJS1_k127_2462329_8 204669.Acid345_0019 3.704e-35 135.0 COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia 204432|Acidobacteriia J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 HSJS1_k127_246572_6 419947.MRA_0081 2.386e-39 154.0 2CYNV@1|root,32T4H@2|Bacteria,2IRMP@201174|Actinobacteria 201174|Actinobacteria S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii HSJS1_k127_246572_1 335543.Sfum_2789 3.509e-94 331.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2MQ7N@213462|Syntrophobacterales 28221|Deltaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 HSJS1_k127_246572_9 1087481.AGFX01000014_gene2969 5.125e-23 102.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26Y4X@186822|Paenibacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd HSJS1_k127_246572_4 479434.Sthe_0945 2.848e-68 238.0 COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia 189775|Thermomicrobia L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 HSJS1_k127_246572_0 316274.Haur_2569 3.044e-101 346.0 COG0160@1|root,COG0160@2|Bacteria,2G5RV@200795|Chloroflexi,3763X@32061|Chloroflexia 32061|Chloroflexia H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 HSJS1_k127_246572_5 391625.PPSIR1_24934 5.588e-67 234.0 COG0125@1|root,COG0125@2|Bacteria 2|Bacteria F dTDP biosynthetic process tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM1099 AAA_28,Thymidylate_kin HSJS1_k127_246572_11 1173027.Mic7113_0649 6.652e-11 73.0 COG0664@1|root,COG0664@2|Bacteria,1G57E@1117|Cyanobacteria,1HAIX@1150|Oscillatoriales 1117|Cyanobacteria T - catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - cNMP_binding HSJS1_k127_246572_8 483219.LILAB_17575 1.402e-24 115.0 COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales 28221|Deltaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding HSJS1_k127_246572_3 518766.Rmar_1923 2.88e-82 289.0 COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L NUDIX domain mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 HSJS1_k127_246572_7 1411685.U062_02066 1.134e-31 130.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1J6KX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease HSJS1_k127_246572_2 382464.ABSI01000010_gene3269 3.814e-87 300.0 COG3608@1|root,COG3608@2|Bacteria 2|Bacteria G succinylglutamate desuccinylase aspartoacylase doeB - - ko:K06987 - - - - ko00000 - - - AstE_AspA HSJS1_k127_246612_0 1297742.A176_06954 1.14e-05 47.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N HSJS1_k127_2467303_9 1450694.BTS2_0998 0.0003365 45.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,1ZCR0@1386|Bacillus 91061|Bacilli H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC HSJS1_k127_2467303_2 314278.NB231_00260 5.595e-140 451.0 KOG2165@1|root,2Z911@2|Bacteria,1N8JM@1224|Proteobacteria,1RR9Z@1236|Gammaproteobacteria,1WWIT@135613|Chromatiales 135613|Chromatiales S ubiquitin protein ligase binding - - - - - - - - - - - - - HSJS1_k127_2467303_0 472759.Nhal_3586 6.038e-314 983.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X0IX@135613|Chromatiales 135613|Chromatiales S PFAM peptidase S15 - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 HSJS1_k127_2467303_4 472759.Nhal_3587 7.23e-114 379.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria,1X0FH@135613|Chromatiales 135613|Chromatiales F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C HSJS1_k127_2467303_8 1232410.KI421412_gene337 5.983e-13 72.0 2C59E@1|root,2ZDAY@2|Bacteria 2|Bacteria S OsmC-like protein - - - - - - - - - - - - OsmC HSJS1_k127_2467303_6 1232410.KI421412_gene336 3.173e-18 92.0 29SGJ@1|root,2ZKKB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2467303_1 1128421.JAGA01000002_gene660 6.909e-225 712.0 COG1960@1|root,COG1960@2|Bacteria 2|Bacteria I acyl-CoA dehydrogenase activity - - - ko:K09456 - - - - ko00000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M HSJS1_k127_2467303_3 398579.Spea_1841 9.562e-116 387.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1RMBY@1236|Gammaproteobacteria,2QAXR@267890|Shewanellaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_2467303_5 1236541.BALL01000005_gene873 2.157e-50 196.0 COG0845@1|root,COG0845@2|Bacteria,1RCT0@1224|Proteobacteria,1S3AD@1236|Gammaproteobacteria,2QABY@267890|Shewanellaceae 1236|Gammaproteobacteria M HlyD family secretion protein - - - - - - - - - - - - HlyD_3,HlyD_D23 HSJS1_k127_2467303_7 1167006.UWK_02476 8.989e-15 85.0 COG0845@1|root,COG0845@2|Bacteria,1RCT0@1224|Proteobacteria 1224|Proteobacteria M membrane-fusion protein - - - - - - - - - - - - HlyD_3,HlyD_D23 HSJS1_k127_2473673_1 246197.MXAN_1283 3.908e-63 223.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales 28221|Deltaproteobacteria C Dehydrogenase - - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh HSJS1_k127_2473673_0 866536.Belba_3417 7.363e-97 328.0 COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47JWT@768503|Cytophagia 976|Bacteroidetes S integral membrane protein - - - - - - - - - - - - DUF819 HSJS1_k127_2477068_1 392499.Swit_3706 2.021e-112 366.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,2KEBC@204457|Sphingomonadales 204457|Sphingomonadales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_2477068_0 1288826.MSNKSG1_01953 3.004e-122 412.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,46A8T@72275|Alteromonadaceae 1236|Gammaproteobacteria U ABC-2 family transporter protein ybhS GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 HSJS1_k127_2491230_0 1041147.AUFB01000094_gene5706 2.798e-141 464.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U1Z0@28211|Alphaproteobacteria,4BMWU@82115|Rhizobiaceae 28211|Alphaproteobacteria L Reverse transcriptase (RNA-dependent DNA polymerase) - - 2.7.7.49 ko:K00986,ko:K15342 - - - - ko00000,ko01000,ko02048,ko03400 - - - Cas_Cas1,GIIM,RVT_1 HSJS1_k127_2492954_2 1144275.COCOR_01976 0.0002844 47.0 COG0457@1|root,COG3266@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria 2|Bacteria GM domain, Protein oapA - 2.7.7.7,3.1.26.12 ko:K02343,ko:K02451,ko:K06867,ko:K07268,ko:K08300 ko00230,ko00240,ko01100,ko03018,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03018,map03030,map03430,map03440 M00260,M00331,M00394 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko02044,ko03009,ko03019,ko03032,ko03400 9.B.42 - - Collagen,DNA_pol3_tau_5,OapA,OapA_N,T2SSB HSJS1_k127_2492954_0 283942.IL2339 5.14e-209 687.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,2QGC4@267893|Idiomarinaceae 1236|Gammaproteobacteria P Outer membrane receptor - - - - - - - - - - - - CarboxypepD_reg,Plug HSJS1_k127_2492954_1 234267.Acid_4013 1.375e-10 74.0 COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria 57723|Acidobacteria S oxidoreductase activity - - - - - - - - - - - - - HSJS1_k127_2495482_0 713586.KB900536_gene1925 1.296e-148 496.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales 135613|Chromatiales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge HSJS1_k127_2495482_3 1121920.AUAU01000023_gene2415 6.385e-39 156.0 COG0664@1|root,COG1716@1|root,COG0664@2|Bacteria,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - FHA,cNMP_binding HSJS1_k127_2495482_2 292459.STH2808 1.293e-50 193.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia 186801|Clostridia V LD-carboxypeptidase - - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 HSJS1_k127_2495482_4 362663.ECP_3213 1.853e-09 70.0 2DMTH@1|root,32TKP@2|Bacteria,1N4TE@1224|Proteobacteria,1S9K6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2495482_5 1349820.M707_07595 5.84e-07 62.0 COG0484@1|root,COG0484@2|Bacteria,2IDAA@201174|Actinobacteria,1W86U@1268|Micrococcaceae 201174|Actinobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ HSJS1_k127_2495482_1 204669.Acid345_4314 1.106e-96 326.0 COG4941@1|root,COG4941@2|Bacteria,3Y42G@57723|Acidobacteria,2JM1K@204432|Acidobacteriia 204432|Acidobacteriia K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2 HSJS1_k127_2497960_1 439235.Dalk_1403 1.094e-30 123.0 2E9H4@1|root,333Q5@2|Bacteria,1N6SM@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2497960_0 886293.Sinac_3650 3.299e-70 254.0 COG2318@1|root,COG2318@2|Bacteria,2IZ34@203682|Planctomycetes 203682|Planctomycetes S Mycothiol maleylpyruvate isomerase N-terminal domain - - - - - - - - - - - - MDMPI_N HSJS1_k127_2497960_2 485913.Krac_9318 1.305e-27 117.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 HSJS1_k127_2502291_4 1192034.CAP_0266 1.552e-11 77.0 COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YWD2@29|Myxococcales 28221|Deltaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin HSJS1_k127_2502291_5 1240349.ANGC01000009_gene2802 9.843e-08 64.0 COG1752@1|root,COG1752@2|Bacteria,2IFBM@201174|Actinobacteria,4FXHB@85025|Nocardiaceae 201174|Actinobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin HSJS1_k127_2502291_0 883080.HMPREF9697_02192 1.232e-124 425.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HSJS1_k127_2502291_3 452637.Oter_2327 1.162e-78 290.0 COG0457@1|root,COG0457@2|Bacteria 452637.Oter_2327|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_2502291_2 1122603.ATVI01000005_gene3782 9.355e-80 294.0 COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,1RXZC@1236|Gammaproteobacteria,1X60Q@135614|Xanthomonadales 135614|Xanthomonadales S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 HSJS1_k127_2502291_1 179408.Osc7112_2549 2.633e-100 347.0 COG2303@1|root,COG2303@2|Bacteria,1G4B3@1117|Cyanobacteria,1HHEE@1150|Oscillatoriales 1117|Cyanobacteria C Belongs to the GMC oxidoreductase family - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N HSJS1_k127_2503390_0 869210.Marky_1283 3.66e-272 859.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1WIA7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E PFAM Conserved region in glutamate synthase - - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase HSJS1_k127_2503390_1 272123.Anacy_0923 1.485e-33 133.0 COG1569@1|root,COG1569@2|Bacteria,1G8QQ@1117|Cyanobacteria 1117|Cyanobacteria S Toxin-antitoxin system, toxin component, PIN family - - - - - - - - - - - - PIN_3 HSJS1_k127_2503390_2 555779.Dthio_PD0777 3.918e-18 88.0 2DFHS@1|root,2ZRWH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2503414_2 439235.Dalk_4746 8.466e-36 142.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria,2MJ1B@213118|Desulfobacterales 28221|Deltaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B,Lactamase_B_2 HSJS1_k127_2503414_3 1144343.PMI41_04598 8.875e-20 98.0 COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,43KV4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - PurS HSJS1_k127_2503414_1 522772.Dacet_1987 1.548e-87 294.0 COG0047@1|root,COG0047@2|Bacteria,2GEQB@200930|Deferribacteres 200930|Deferribacteres F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 HSJS1_k127_2503414_0 1297742.A176_06444 8.663e-127 424.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales 28221|Deltaproteobacteria V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_2503802_1 382464.ABSI01000010_gene3321 7.908e-07 60.0 COG2706@1|root,COG3210@1|root,COG4733@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Lactonase HSJS1_k127_2503802_0 575540.Isop_2577 2.788e-22 100.0 COG0500@1|root,COG2226@2|Bacteria,2IYB6@203682|Planctomycetes 203682|Planctomycetes Q Methylase involved in ubiquinone menaquinone - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 HSJS1_k127_2510765_2 192952.MM_1588 9.201e-11 72.0 COG3291@1|root,arCOG02510@2157|Archaea,arCOG05189@2157|Archaea,2Y30D@28890|Euryarchaeota,2NAGI@224756|Methanomicrobia 224756|Methanomicrobia S Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - NosD,PKD HSJS1_k127_2510765_1 511.JT27_05905 4.93e-26 122.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria,3T2K8@506|Alcaligenaceae 28216|Betaproteobacteria I Fatty acid fadL - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X HSJS1_k127_2510765_0 1345695.CLSA_c21550 5.27e-104 357.0 COG0457@1|root,COG0457@2|Bacteria,1UJ9T@1239|Firmicutes,24CZA@186801|Clostridia,36G3G@31979|Clostridiaceae 186801|Clostridia S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 HSJS1_k127_2514530_1 388467.A19Y_0102 5.856e-36 153.0 COG2755@1|root,COG2755@2|Bacteria,1G3Y8@1117|Cyanobacteria,1H8QZ@1150|Oscillatoriales 1117|Cyanobacteria E SGNH hydrolase-like domain, acetyltransferase AlgX - - - - - - - - - - - - ALGX HSJS1_k127_2514530_0 742159.HMPREF0004_0190 4.372e-43 171.0 COG1541@1|root,COG1541@2|Bacteria,1NR5G@1224|Proteobacteria,2VHRP@28216|Betaproteobacteria,3T77K@506|Alcaligenaceae 28216|Betaproteobacteria H Acyl-protein synthetase, LuxE luxE - - - - - - - - - - - LuxE HSJS1_k127_2523389_0 592027.CLG_B0074 1.343e-101 339.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,36DNY@31979|Clostridiaceae 186801|Clostridia E Methionine aminopeptidase - - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24,SEC-C HSJS1_k127_2523389_2 290397.Adeh_0163 5.353e-31 140.0 COG1451@1|root,COG1451@2|Bacteria 2|Bacteria S Protein of unknown function DUF45 CP_0175 - - ko:K07043 - - - - ko00000 - - - DUF45,SprT-like HSJS1_k127_2523389_1 118168.MC7420_4544 4.13e-62 230.0 COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HASA@1150|Oscillatoriales 1117|Cyanobacteria S KWG Leptospira - - - - - - - - - - - - WG_beta_rep HSJS1_k127_2525106_1 926566.Terro_1682 5.503e-17 91.0 COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria,2JJBA@204432|Acidobacteriia 204432|Acidobacteriia L recA bacterial DNA recombination protein - - - - - - - - - - - - RecA HSJS1_k127_2525106_0 1396141.BATP01000035_gene4101 1.309e-105 353.0 COG0498@1|root,COG0498@2|Bacteria,46TPG@74201|Verrucomicrobia,2IU9P@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Threonine synthase N terminus - - - - - - - - - - - - PALP,Thr_synth_N HSJS1_k127_2541864_0 237368.SCABRO_00848 6.062e-47 177.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - DUF4157,PG_binding_1 HSJS1_k127_2545079_1 1123368.AUIS01000003_gene1777 2.567e-134 441.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,2NBU3@225057|Acidithiobacillales 225057|Acidithiobacillales O MCM2/3/5 family - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C HSJS1_k127_2545079_0 1260251.SPISAL_07325 1.752e-255 800.0 COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1X2EG@135613|Chromatiales 135613|Chromatiales P PUA-like domain - - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 HSJS1_k127_2545079_2 1048834.TC41_2569 2.833e-53 204.0 COG0483@1|root,COG0483@2|Bacteria,1UKWB@1239|Firmicutes,4ITKN@91061|Bacilli 91061|Bacilli G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P HSJS1_k127_2546496_0 234267.Acid_5088 4.814e-208 659.0 COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria 57723|Acidobacteria C Aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HSJS1_k127_2546496_2 395961.Cyan7425_4864 4.661e-05 57.0 COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,3KG3Y@43988|Cyanothece 1117|Cyanobacteria M O-antigen polymerase ictB - - ko:K18814 - - - - ko00000,ko02000 9.B.67.1 - - Wzy_C HSJS1_k127_2546496_1 215803.DB30_6730 1.951e-48 185.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria,2YW8C@29|Myxococcales 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GAF,GGDEF HSJS1_k127_254786_0 756272.Plabr_3820 5.224e-34 139.0 COG2931@1|root,COG2931@2|Bacteria,2J53M@203682|Planctomycetes 203682|Planctomycetes C Animal haem peroxidase - - - - - - - - - - - - An_peroxidase HSJS1_k127_2548318_4 269799.Gmet_1137 3.49e-42 156.0 COG3500@1|root,COG3500@2|Bacteria,1QK0F@1224|Proteobacteria,42T0N@68525|delta/epsilon subdivisions,2WPW1@28221|Deltaproteobacteria,43VVG@69541|Desulfuromonadales 28221|Deltaproteobacteria S Late control gene D protein - - - - - - - - - - - - - HSJS1_k127_2548318_1 269799.Gmet_1138 3.398e-119 391.0 COG3501@1|root,COG3501@2|Bacteria,1R540@1224|Proteobacteria,42Q1X@68525|delta/epsilon subdivisions,2WM75@28221|Deltaproteobacteria,43VDG@69541|Desulfuromonadales 28221|Deltaproteobacteria S Baseplate assembly protein - - - - - - - - - - - - - HSJS1_k127_2548318_3 269799.Gmet_1139 6.831e-49 177.0 COG3628@1|root,COG3628@2|Bacteria,1N039@1224|Proteobacteria,43DQ3@68525|delta/epsilon subdivisions,2WR64@28221|Deltaproteobacteria,43VVC@69541|Desulfuromonadales 28221|Deltaproteobacteria S Gene 25-like lysozyme - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 HSJS1_k127_2548318_0 269799.Gmet_1140 1.808e-150 486.0 COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,42MUS@68525|delta/epsilon subdivisions,2WK02@28221|Deltaproteobacteria 28221|Deltaproteobacteria S homolog of phage Mu protein gp47 - - - - - - - - - - - - - HSJS1_k127_2548318_2 269799.Gmet_1141 2.229e-64 237.0 COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,437D2@68525|delta/epsilon subdivisions,2XA15@28221|Deltaproteobacteria,43VQR@69541|Desulfuromonadales 28221|Deltaproteobacteria S homolog of phage Mu protein gp47 - - - - - - - - - - - - - HSJS1_k127_2554147_0 502025.Hoch_6445 2.975e-215 683.0 COG3488@1|root,COG3488@2|Bacteria 2|Bacteria C Di-haem oxidoreductase, putative peroxidase - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - DHOR HSJS1_k127_2559908_2 472759.Nhal_1054 7.816e-68 256.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1WWF7@135613|Chromatiales 135613|Chromatiales H TonB-dependent Receptor Plug - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec HSJS1_k127_2559908_3 404589.Anae109_0356 4.182e-64 241.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2Z357@29|Myxococcales 28221|Deltaproteobacteria Q Domain of unknown function (DUF2437) - - - - - - - - - - - - DUF2437,FAA_hydrolase HSJS1_k127_2559908_6 1123504.JQKD01000002_gene3884 3.599e-19 89.0 2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria,4AFCE@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2559908_4 321332.CYB_2318 1.65e-30 135.0 COG1011@1|root,COG1011@2|Bacteria,1G51I@1117|Cyanobacteria,1H0H2@1129|Synechococcus 1117|Cyanobacteria S Haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase HSJS1_k127_2559908_5 1219626.HMPREF1639_02710 4.509e-22 102.0 COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25RD2@186804|Peptostreptococcaceae 186801|Clostridia K Transcriptional regulator iscR - - - - - - - - - - - Rrf2 HSJS1_k127_2559908_1 234267.Acid_1587 8.734e-95 330.0 COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria 57723|Acidobacteria NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE HSJS1_k127_2559908_0 1163407.UU7_07288 9.757e-102 363.0 COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales 135614|Xanthomonadales Q Lamin Tail Domain - - - - - - - - - - - - Calx-beta,LTD HSJS1_k127_2559908_8 1317122.ATO12_10550 3.079e-13 84.0 COG2374@1|root,COG2374@2|Bacteria,4PKDU@976|Bacteroidetes,1IJ8H@117743|Flavobacteriia,2YIIA@290174|Aquimarina 976|Bacteroidetes S Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - Exo_endo_phos,LTD HSJS1_k127_2563507_2 903818.KI912268_gene1848 5.43e-05 48.0 2CI12@1|root,338T1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2563507_0 234267.Acid_7369 2.227e-197 634.0 COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria 57723|Acidobacteria S PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_3 HSJS1_k127_2563507_1 572477.Alvin_1456 1.316e-23 114.0 COG1566@1|root,COG1566@2|Bacteria,1RBK7@1224|Proteobacteria,1S241@1236|Gammaproteobacteria,1X2HT@135613|Chromatiales 135613|Chromatiales V HlyD family secretion protein - - - ko:K01993 - - - - ko00000 - - - HlyD_3 HSJS1_k127_2565672_0 83219.PM02_09410 4.663e-68 257.0 2A642@1|root,30UWI@2|Bacteria,1P3HY@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2565672_1 83219.PM02_09415 1.541e-54 204.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,3ZY7I@60136|Sulfitobacter 28211|Alphaproteobacteria GM NAD dependent epimerase/dehydratase family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - 3Beta_HSD,Epimerase HSJS1_k127_2566842_0 404589.Anae109_1366 1.968e-51 189.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2YVJK@29|Myxococcales 28221|Deltaproteobacteria D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf HSJS1_k127_2566842_3 644282.Deba_0647 8.859e-22 99.0 2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2566842_1 582515.KR51_00008580 1.358e-32 136.0 COG0565@1|root,COG0565@2|Bacteria,1G18I@1117|Cyanobacteria 1117|Cyanobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase HSJS1_k127_2566842_5 1357272.AVEO02000066_gene439 1.261e-05 54.0 COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria 1224|Proteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE9 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_2566842_2 43759.JNWK01000035_gene3298 2.827e-30 136.0 COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria 201174|Actinobacteria G 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase HSJS1_k127_2566842_4 498848.TaqDRAFT_4567 3.997e-07 61.0 COG3635@1|root,COG3635@2|Bacteria,1WJ8Z@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate apgM - 5.4.2.12 ko:K15635 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,PhosphMutase HSJS1_k127_2568633_2 411467.BACCAP_00899 4.892e-05 54.0 COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,268BT@186813|unclassified Clostridiales 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Rhomboid HSJS1_k127_2568633_0 518766.Rmar_2049 9.374e-291 911.0 COG1506@1|root,COG2706@1|root,COG1506@2|Bacteria,COG2706@2|Bacteria,4PIC9@976|Bacteroidetes,1FKAR@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E 6-phosphogluconolactonase activity - - - - - - - - - - - - - HSJS1_k127_2569136_0 378806.STAUR_7163 1.56e-188 617.0 COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,1R7I2@1224|Proteobacteria,434CH@68525|delta/epsilon subdivisions,2X37B@28221|Deltaproteobacteria,2YUP0@29|Myxococcales 28221|Deltaproteobacteria KLTV Lanthionine synthetase C-like protein - - - - - - - - - - - - LANC_like,Pkinase HSJS1_k127_2570380_1 1121918.ARWE01000001_gene2756 5.929e-54 210.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,43T6F@69541|Desulfuromonadales 28221|Deltaproteobacteria S Pfam:UPF0118 - - - - - - - - - - - - AI-2E_transport HSJS1_k127_2570380_0 246197.MXAN_5856 2.42e-321 993.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C HSJS1_k127_2571141_1 1121920.AUAU01000006_gene258 6.994e-92 335.0 COG2235@1|root,COG2235@2|Bacteria,3Y86Y@57723|Acidobacteria 57723|Acidobacteria E Amidinotransferase - - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf HSJS1_k127_2571141_0 903814.ELI_1219 8.861e-149 505.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25V1Q@186806|Eubacteriaceae 186801|Clostridia F adenylosuccinate lyase purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 HSJS1_k127_2571141_3 796620.VIBC2010_05109 2.801e-28 123.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XWTA@135623|Vibrionales 135623|Vibrionales Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4114,HemolysinCabind HSJS1_k127_2571426_0 205922.Pfl01_3623 1.544e-28 130.0 COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RZB6@1236|Gammaproteobacteria,1YP5Z@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria MU Outer membrane efflux protein czcC - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP HSJS1_k127_2576391_0 497964.CfE428DRAFT_2531 1.317e-40 173.0 COG1216@1|root,COG4976@1|root,COG1216@2|Bacteria,COG4976@2|Bacteria,46W0C@74201|Verrucomicrobia 74201|Verrucomicrobia S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_2577204_1 1121920.AUAU01000013_gene1762 3.306e-14 78.0 COG0828@1|root,COG0828@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 HSJS1_k127_2577204_0 1232410.KI421412_gene99 1.66e-61 230.0 COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2WK5H@28221|Deltaproteobacteria,43RYU@69541|Desulfuromonadales 28221|Deltaproteobacteria L ATPase domain of DNA mismatch repair MUTS family mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr HSJS1_k127_2578725_5 309807.SRU_1701 2.504e-24 111.0 COG1960@1|root,COG3793@1|root,COG1960@2|Bacteria,COG3793@2|Bacteria,4NF87@976|Bacteroidetes,1FJZY@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes IP Acyl-CoA oxidase - - 1.3.3.6 ko:K00232 ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146 M00087,M00113 R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_2578725_7 926560.KE387023_gene2647 5.188e-21 104.0 COG0596@1|root,COG0596@2|Bacteria,1WN2Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Transposase and inactivated derivatives - - - - - - - - - - - - - HSJS1_k127_2578725_6 469382.Hbor_12380 1.864e-22 104.0 COG4460@1|root,2N65Q@2157|Archaea,2Y5QA@28890|Euryarchaeota,2409H@183963|Halobacteria 183963|Halobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 HSJS1_k127_2578725_3 572477.Alvin_0757 1.072e-83 290.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales 135613|Chromatiales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo HSJS1_k127_2578725_4 1122970.AUHC01000004_gene2195 1.189e-34 145.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,2K1VU@204457|Sphingomonadales 204457|Sphingomonadales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 HSJS1_k127_2578725_0 1121937.AUHJ01000011_gene2857 4.236e-116 383.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,4651S@72275|Alteromonadaceae 1236|Gammaproteobacteria C Lysine 2,3-aminomutase YodO family protein epmB GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569 Fer4_12,Fer4_14,Radical_SAM HSJS1_k127_2578725_2 713587.THITH_13100 7.327e-88 299.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales 135613|Chromatiales J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C HSJS1_k127_2578725_1 1265313.HRUBRA_01500 1.435e-97 331.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1J5W0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Elongation factor P--(R)-beta-lysine ligase epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 HSJS1_k127_2578725_8 1122939.ATUD01000002_gene1314 1.373e-07 60.0 COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria 84995|Rubrobacteria H Mur ligase family, glutamate ligase domain - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M HSJS1_k127_2580761_0 1303518.CCALI_02898 1.61e-225 710.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC HSJS1_k127_2584152_1 926569.ANT_08690 6.317e-46 176.0 COG5624@1|root,COG5624@2|Bacteria,2G94N@200795|Chloroflexi 200795|Chloroflexi K Conserved repeat domain - - - - - - - - - - - - - HSJS1_k127_2584152_2 1122179.KB890443_gene1223 4.587e-11 73.0 COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes 976|Bacteroidetes T Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg HSJS1_k127_2584152_0 1122139.KB907877_gene3005 3.596e-46 175.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1XH38@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase HSJS1_k127_2588587_1 247490.KSU1_D0504 2.863e-78 274.0 COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Peripla_BP_6 HSJS1_k127_2588587_0 706587.Desti_1742 6.225e-80 281.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria,2MR5I@213462|Syntrophobacterales 28221|Deltaproteobacteria T PFAM response regulator receiver - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_2590011_7 871968.DESME_09130 2.099e-08 67.0 COG3391@1|root,COG3391@2|Bacteria,1V2KS@1239|Firmicutes,24FSD@186801|Clostridia 186801|Clostridia S PFAM NHL repeat containing protein - - - - - - - - - - - - NHL HSJS1_k127_2590011_6 1144275.COCOR_05991 6.918e-09 69.0 COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YZ03@29|Myxococcales 28221|Deltaproteobacteria S Kelch motif - - - - - - - - - - - - Kelch_1,Kelch_4,Kelch_6,PKD HSJS1_k127_2590011_5 1090318.ATTI01000002_gene37 3.412e-09 70.0 COG1595@1|root,COG2771@1|root,COG1595@2|Bacteria,COG2771@2|Bacteria,1N1RJ@1224|Proteobacteria,2UEAJ@28211|Alphaproteobacteria,2K7GB@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE HSJS1_k127_2590011_1 880073.Calab_1263 6.37e-43 173.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Paired_CXXCH_1 HSJS1_k127_2590011_4 338969.Rfer_0259 2.161e-35 147.0 COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria 28216|Betaproteobacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 HSJS1_k127_2590011_3 443143.GM18_0934 2.25e-37 154.0 COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,43AJ0@68525|delta/epsilon subdivisions,2X5Z8@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM NHL repeat containing protein - - - - - - - - - - - - - HSJS1_k127_2590011_2 243231.GSU0618 1.338e-41 162.0 COG3303@1|root,COG3303@2|Bacteria,1RG2D@1224|Proteobacteria 1224|Proteobacteria P Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 HSJS1_k127_2590011_0 1158338.JNLJ01000001_gene945 5.161e-58 212.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - DUF5128,NHL,TPR_11 HSJS1_k127_2592498_6 926550.CLDAP_05840 8.06e-17 92.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G903@200795|Chloroflexi 200795|Chloroflexi S CHAT domain - - - - - - - - - - - - CHAT HSJS1_k127_2592498_5 522306.CAP2UW1_3870 1.03e-17 95.0 COG1310@1|root,COG1310@2|Bacteria,1QUDB@1224|Proteobacteria 1224|Proteobacteria S metal-dependent protease of the Pad1 Jab1 superfamily - - - - - - - - - - - - - HSJS1_k127_2592498_7 861299.J421_3908 1.951e-14 81.0 COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes 142182|Gemmatimonadetes K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_2592498_2 497965.Cyan7822_3560 8.56e-130 452.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,3KGI4@43988|Cyanothece 1117|Cyanobacteria N PFAM TPR repeat-containing protein - - - - - - - - - - - - CHAT,TPR_12,TPR_8 HSJS1_k127_2592498_4 1499967.BAYZ01000135_gene87 2.989e-28 130.0 COG4249@1|root,COG4249@2|Bacteria,2NQXX@2323|unclassified Bacteria 2|Bacteria S Caspase domain atmc2 - - - - - - - - - - - Peptidase_C14 HSJS1_k127_2592498_0 1353531.AZNX01000006_gene5597 1.396e-174 557.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2TU6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Radical SAM superfamily - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM HSJS1_k127_2592498_3 313612.L8106_04436 2.566e-91 326.0 COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1FZWU@1117|Cyanobacteria,1H8MG@1150|Oscillatoriales 1117|Cyanobacteria T GGDEF domain' - - - - - - - - - - - - CBS,GAF,GAF_2,GGDEF,PAS_3,PAS_4,PAS_8,PAS_9 HSJS1_k127_2592498_1 518766.Rmar_1066 3.106e-141 468.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1FIX6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase HSJS1_k127_2594290_2 1380386.JIAW01000022_gene2230 0.000643 53.0 COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,235YH@1762|Mycobacteriaceae 201174|Actinobacteria K luxR family - - - - - - - - - - - - AAA_16,GerE,TPR_12 HSJS1_k127_2594290_0 1379698.RBG1_1C00001G1660 1.157e-108 379.0 COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria 2|Bacteria S von Willebrand factor (vWF) type A domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA_2 HSJS1_k127_2594290_1 1379698.RBG1_1C00001G1661 7.46e-103 345.0 COG1239@1|root,COG1239@2|Bacteria,2NQQG@2323|unclassified Bacteria 2|Bacteria H Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX chlI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - iNJ661.Rv0958 Mg_chelatase,Sigma54_activat HSJS1_k127_2597400_1 1382359.JIAL01000001_gene2434 3.137e-09 67.0 COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia 204432|Acidobacteriia M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - TonB_C HSJS1_k127_2597400_0 7739.XP_002588034.1 5.803e-16 88.0 KOG3577@1|root,KOG4297@1|root,KOG4729@1|root,KOG3577@2759|Eukaryota,KOG4297@2759|Eukaryota,KOG4729@2759|Eukaryota 2759|Eukaryota O carbohydrate binding - - - ko:K09614 - - - - ko00000,ko01000,ko01002 - - - Fz,Ldl_recept_a HSJS1_k127_2603369_5 1123508.JH636441_gene3511 3.503e-35 147.0 COG0457@1|root,COG0463@1|root,COG1216@1|root,COG2227@1|root,COG4641@1|root,COG5010@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,COG4641@2|Bacteria,COG5010@2|Bacteria,2J07E@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_trans_1_2,Glycos_transf_2,Methyltransf_23,TPR_16,TPR_19,TPR_7,TPR_8 HSJS1_k127_2603369_4 693986.MOC_6053 7.922e-39 158.0 COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria,2UFTW@28211|Alphaproteobacteria,1JRXX@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_2603369_7 262724.TT_C1407 0.0002889 53.0 COG1470@1|root,COG3895@1|root,COG1470@2|Bacteria,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM PEGA domain - - - - - - - - - - - - DUF4384,PEGA HSJS1_k127_2603369_6 1380346.JNIH01000005_gene3168 2.909e-24 110.0 COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria 201174|Actinobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N HSJS1_k127_2603369_0 926550.CLDAP_25740 1.746e-283 889.0 COG5322@1|root,COG5322@2|Bacteria,2G7SR@200795|Chloroflexi 200795|Chloroflexi S oxidoreductase activity - - - - - - - - - - - - - HSJS1_k127_2603369_3 395961.Cyan7425_1251 3.514e-43 166.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase ermC - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran HSJS1_k127_2603369_2 1232410.KI421421_gene3826 1.405e-55 217.0 COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42T1D@68525|delta/epsilon subdivisions,2X5J9@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 HSJS1_k127_2603369_1 1232410.KI421421_gene3825 1.413e-94 326.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales 28221|Deltaproteobacteria V AcrB/AcrD/AcrF family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_2609130_4 404589.Anae109_0948 6.067e-10 67.0 28S5K@1|root,2ZEH5@2|Bacteria,1NI42@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (FYDLN_acid) - - - - - - - - - - - - FYDLN_acid HSJS1_k127_2609130_2 1385935.N836_17320 8.791e-31 133.0 COG0801@1|root,COG0801@2|Bacteria,1G5NF@1117|Cyanobacteria,1HB2Y@1150|Oscillatoriales 1117|Cyanobacteria H PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK HSJS1_k127_2609130_1 1121468.AUBR01000027_gene2887 1.781e-56 209.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,42EQ0@68295|Thermoanaerobacterales 186801|Clostridia P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer HSJS1_k127_2609130_0 754476.Q7A_2206 2.459e-125 415.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,4604B@72273|Thiotrichales 72273|Thiotrichales C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - ko:K03309 - - - - ko00000 2.A.23 - - SDF HSJS1_k127_2609130_3 926690.KE386573_gene48 3.938e-21 107.0 COG1184@1|root,arCOG01127@2157|Archaea,2XUMH@28890|Euryarchaeota,23SF4@183963|Halobacteria 183963|Halobacteria J Belongs to the eIF-2B alpha beta delta subunits family tif2Ba - - - - - - - - - - - IF-2B,NUDIX HSJS1_k127_2609130_5 335543.Sfum_0584 4.36e-06 52.0 COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria,42VPE@68525|delta/epsilon subdivisions,2WRZ3@28221|Deltaproteobacteria,2MRV3@213462|Syntrophobacterales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TAtT HSJS1_k127_2613786_0 545276.KB898726_gene1113 4.259e-117 383.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales 135613|Chromatiales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran HSJS1_k127_2613786_1 1144275.COCOR_05701 1.338e-39 154.0 28PTG@1|root,2ZCEQ@2|Bacteria,1PCZF@1224|Proteobacteria,433WM@68525|delta/epsilon subdivisions,2X292@28221|Deltaproteobacteria,2YXC4@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2617306_4 1120934.KB894411_gene6730 1.45e-56 201.0 COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4E2WQ@85010|Pseudonocardiales 201174|Actinobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 HSJS1_k127_2617306_6 1122201.AUAZ01000032_gene1588 1.105e-45 173.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,466SE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 HSJS1_k127_2617306_0 404380.Gbem_2756 1.15e-94 317.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,43SZ8@69541|Desulfuromonadales 28221|Deltaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 HSJS1_k127_2617306_2 1121423.JONT01000004_gene1596 1.208e-82 282.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,260PI@186807|Peptococcaceae 186801|Clostridia J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS HSJS1_k127_2617306_1 123214.PERMA_0233 4.484e-92 308.0 COG0528@1|root,COG0528@2|Bacteria,2G3IX@200783|Aquificae 200783|Aquificae F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase HSJS1_k127_2617306_3 234267.Acid_0903 1.357e-57 205.0 COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria 57723|Acidobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF HSJS1_k127_2617306_5 42256.RradSPS_1959 7.788e-48 180.0 COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CPWF@84995|Rubrobacteria 84995|Rubrobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind HSJS1_k127_2628052_3 502025.Hoch_2696 6.271e-51 182.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,43850@68525|delta/epsilon subdivisions,2WX9Z@28221|Deltaproteobacteria,2YWVT@29|Myxococcales 28221|Deltaproteobacteria EU Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 HSJS1_k127_2628052_6 1342299.Z947_1496 0.0003587 53.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U0BU@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Radical SAM - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM HSJS1_k127_2628052_1 671143.DAMO_2352 4.042e-81 283.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity yeeZ - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - Epimerase,NAD_binding_10,RmlD_sub_bind HSJS1_k127_2628052_0 404589.Anae109_1529 5.071e-163 536.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YWT8@29|Myxococcales 28221|Deltaproteobacteria I Amp-dependent synthetase and ligase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding HSJS1_k127_2628052_5 396588.Tgr7_3179 2.684e-07 59.0 COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,1RRYH@1236|Gammaproteobacteria,1X059@135613|Chromatiales 135613|Chromatiales L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA nfi - 3.1.21.7 ko:K05982 - - - - ko00000,ko01000,ko03400 - - - Endonuclease_5 HSJS1_k127_2628052_2 243233.MCA0045 5.38e-63 222.0 COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,1RRYH@1236|Gammaproteobacteria,1XG9S@135618|Methylococcales 135618|Methylococcales L Endonuclease V - - 3.1.21.7 ko:K05982 - - - - ko00000,ko01000,ko03400 - - - Endonuclease_5 HSJS1_k127_2628052_4 580332.Slit_2956 3.115e-11 64.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,44VMU@713636|Nitrosomonadales 28216|Betaproteobacteria S Bacterial transferase hexapeptide (six repeats) yrdA - - - - - - - - - - - Hexapep HSJS1_k127_2644674_3 1396141.BATP01000060_gene4652 1.124e-65 243.0 COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia,2ITZ6@203494|Verrucomicrobiae 203494|Verrucomicrobiae D SMC proteins Flexible Hinge Domain - - - - - - - - - - - - SMC_N,SMC_hinge HSJS1_k127_2644674_1 1128421.JAGA01000002_gene855 1.356e-142 467.0 COG0665@1|root,COG0665@2|Bacteria 2|Bacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO HSJS1_k127_2644674_5 404589.Anae109_3927 1.057e-53 199.0 COG0500@1|root,COG2226@2|Bacteria,1N5DK@1224|Proteobacteria,43CKW@68525|delta/epsilon subdivisions,2X610@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Hypothetical methyltransferase - - - - - - - - - - - - Methyltransf_11 HSJS1_k127_2644674_6 880073.Calab_3797 7.416e-42 177.0 COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria 2|Bacteria T Two component regulator propeller - - - - - - - - - - - - HATPase_c,HisKA,HisKA_2,HisKA_3,PAS_9,Reg_prop,Response_reg,SpoIIE,Y_Y_Y HSJS1_k127_2644674_11 215803.DB30_5765 7.687e-10 72.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA HSJS1_k127_2644674_7 344747.PM8797T_25506 4.832e-37 151.0 2CNMZ@1|root,32SHD@2|Bacteria,2J3XH@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_2644674_2 1254432.SCE1572_30880 1.53e-67 237.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx HSJS1_k127_2644674_8 1267535.KB906767_gene784 3.708e-24 112.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_2644674_0 1183438.GKIL_4354 1.947e-175 583.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_2644674_4 1123053.AUDG01000035_gene746 1.212e-55 205.0 COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,1SC72@1236|Gammaproteobacteria 1236|Gammaproteobacteria M lysozyme activity yegX - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 HSJS1_k127_2654361_2 926560.KE387026_gene4310 1.903e-43 168.0 COG4101@1|root,COG4101@2|Bacteria 2|Bacteria G 3-hydroxyanthranilate 3,4-dioxygenase activity - - - - - - - - - - - - Cupin_2 HSJS1_k127_2654361_1 469383.Cwoe_4725 2.238e-107 356.0 COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4CRGK@84995|Rubrobacteria 84995|Rubrobacteria I Enoyl-CoA hydratase/isomerase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 HSJS1_k127_2654361_0 1121013.P873_11010 1.028e-170 556.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Prolyl oligopeptidase - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N HSJS1_k127_2656771_2 123214.PERMA_1479 6.616e-14 85.0 COG1538@1|root,COG1538@2|Bacteria,2G3WW@200783|Aquificae 200783|Aquificae MU outer membrane efflux protein - - - - - - - - - - - - OEP HSJS1_k127_2656771_1 638303.Thal_0800 4.722e-33 146.0 COG0845@1|root,COG0845@2|Bacteria,2G40A@200783|Aquificae 200783|Aquificae M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 HSJS1_k127_2656771_0 909663.KI867150_gene1145 8.67e-168 550.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MQA5@213462|Syntrophobacterales 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran HSJS1_k127_266366_1 1385518.N798_15610 9.288e-06 53.0 COG1216@1|root,COG1216@2|Bacteria,2I04I@201174|Actinobacteria,4FGGH@85021|Intrasporangiaceae 201174|Actinobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_3 HSJS1_k127_266366_0 1121931.AUHG01000011_gene2349 2.105e-64 245.0 COG0438@1|root,COG0438@2|Bacteria,4NJR3@976|Bacteroidetes,1HZC6@117743|Flavobacteriia 976|Bacteroidetes M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_2666530_0 1123073.KB899242_gene1168 1.501e-113 386.0 COG5624@1|root,COG5624@2|Bacteria,1P7FN@1224|Proteobacteria,1T85B@1236|Gammaproteobacteria,1XA69@135614|Xanthomonadales 135614|Xanthomonadales K RNA polymerase II activating transcription factor binding - - - - - - - - - - - - - HSJS1_k127_2666530_1 1499967.BAYZ01000049_gene2752 9.258e-26 117.0 COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria 2|Bacteria P Sulfatase - - - - - - - - - - - - Cu-binding_MopE,DUF4976,Sulfatase HSJS1_k127_2667441_6 383372.Rcas_2542 2.368e-05 54.0 2F76J@1|root,33ZMZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2667441_5 471854.Dfer_0264 3.309e-06 61.0 COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia 976|Bacteroidetes G PFAM Fibronectin type III domain - - - - - - - - - - - - fn3 HSJS1_k127_2667441_7 27679.XP_003929396.2 9.093e-05 56.0 KOG1565@1|root,KOG1565@2759|Eukaryota,38HSP@33154|Opisthokonta,3BGIQ@33208|Metazoa,3CZ3Y@33213|Bilateria,486H5@7711|Chordata,48Z87@7742|Vertebrata,3JCK8@40674|Mammalia,35C4C@314146|Euarchontoglires,4MCDA@9443|Primates 33208|Metazoa O Matrix metallopeptidase 28 MMP28 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0016787,GO:0019538,GO:0031012,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.24.80 ko:K07763,ko:K08006 ko04668,ko04912,map04668,map04912 - - - ko00000,ko00001,ko01000,ko01002 - - - Hemopexin,PG_binding_1,Peptidase_M10 HSJS1_k127_2667441_0 649638.Trad_1706 4.095e-96 334.0 COG0668@1|root,COG0668@2|Bacteria,1WKQW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M PFAM Mechanosensitive ion channel - - - - - - - - - - - - MS_channel HSJS1_k127_2667441_2 342949.PNA2_1571 9.758e-86 301.0 COG0733@1|root,arCOG04466@2157|Archaea,2XTG1@28890|Euryarchaeota,243E0@183968|Thermococci 183968|Thermococci P Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF HSJS1_k127_2667441_1 479434.Sthe_0155 3.081e-87 295.0 COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi,27XKP@189775|Thermomicrobia 189775|Thermomicrobia K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg HSJS1_k127_2667441_3 525904.Tter_1108 1.412e-78 271.0 COG3850@1|root,COG3850@2|Bacteria,2NS42@2323|unclassified Bacteria 2|Bacteria T histidine kinase dimerisation and phosphoacceptor region - - 2.7.13.3 ko:K03406,ko:K07673,ko:K07675 ko02020,ko02030,map02020,map02030 M00471,M00473 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N,MFS_1 HSJS1_k127_2667925_3 575540.Isop_1561 0.0001407 48.0 COG0515@1|root,COG0515@2|Bacteria 575540.Isop_1561|- KLT protein kinase activity - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - - HSJS1_k127_2667925_0 391625.PPSIR1_12543 1.962e-225 707.0 COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,42X2Z@68525|delta/epsilon subdivisions,2WTRX@28221|Deltaproteobacteria,2YTSH@29|Myxococcales 28221|Deltaproteobacteria FH Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur HSJS1_k127_2667925_2 861299.J421_3911 9.51e-12 76.0 COG4758@1|root,COG4758@2|Bacteria 2|Bacteria KT membrane yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 HSJS1_k127_2667925_1 1125971.ASJB01000015_gene5744 1.926e-61 218.0 COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4DXYI@85010|Pseudonocardiales 201174|Actinobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh HSJS1_k127_2673976_0 861299.J421_4258 3.391e-164 527.0 COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes 142182|Gemmatimonadetes L DEAD-like helicases superfamily - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C HSJS1_k127_2673976_1 84531.JMTZ01000070_gene1816 2.7e-116 390.0 COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales 135614|Xanthomonadales I Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase HSJS1_k127_2673976_2 1122176.KB903542_gene386 2.037e-32 139.0 COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1IU69@117747|Sphingobacteriia 976|Bacteroidetes S Erythromycin esterase - - - ko:K06880 - - - - ko00000,ko01000,ko01504 - - - Erythro_esteras HSJS1_k127_2673976_3 189426.PODO_14540 6.824e-09 66.0 COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,26SUB@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 HSJS1_k127_267680_3 861299.J421_1437 2.763e-31 139.0 COG3794@1|root,COG3794@2|Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Cupredoxin_1 HSJS1_k127_267680_1 1121920.AUAU01000001_gene2198 8.107e-65 251.0 COG0515@1|root,COG0515@2|Bacteria,3Y7IX@57723|Acidobacteria 57723|Acidobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - HAMP,Pkinase HSJS1_k127_267680_0 304371.MCP_2125 1.561e-69 241.0 COG1467@1|root,arCOG04110@2157|Archaea 2157|Archaea F Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - - HSJS1_k127_2678163_0 246197.MXAN_0222 6.084e-127 412.0 COG0604@1|root,COG0604@2|Bacteria,1QY04@1224|Proteobacteria,43AHJ@68525|delta/epsilon subdivisions,2X5XS@28221|Deltaproteobacteria,2YUNY@29|Myxococcales 28221|Deltaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 HSJS1_k127_2678163_1 575540.Isop_1386 1.308e-101 342.0 COG0388@1|root,COG0388@2|Bacteria,2IZEX@203682|Planctomycetes 203682|Planctomycetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase HSJS1_k127_2678163_4 903818.KI912269_gene182 0.0003713 51.0 2EGCD@1|root,33A46@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4190,Septum_form HSJS1_k127_2678163_2 1298867.AUES01000004_gene508 1.816e-26 123.0 COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,2TTX7@28211|Alphaproteobacteria,3JSCR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi HSJS1_k127_2678163_3 909663.KI867150_gene2754 1.251e-21 96.0 COG2442@1|root,COG2442@2|Bacteria,1NH1S@1224|Proteobacteria,42X0V@68525|delta/epsilon subdivisions,2WRHP@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 HSJS1_k127_2680582_2 247490.KSU1_D0161 3.183e-13 84.0 COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes 203682|Planctomycetes L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C HSJS1_k127_2680582_3 1207063.P24_18052 0.0009351 53.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,2JR61@204441|Rhodospirillales 204441|Rhodospirillales L PD-(D/E)XK nuclease superfamily - - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 HSJS1_k127_2680582_1 330214.NIDE2086 1.115e-71 279.0 COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae 40117|Nitrospirae L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C HSJS1_k127_2680582_0 1144275.COCOR_03285 3.994e-140 476.0 COG0778@1|root,COG0778@2|Bacteria,1R0E8@1224|Proteobacteria,43CWT@68525|delta/epsilon subdivisions,2X84S@28221|Deltaproteobacteria,2Z3KW@29|Myxococcales 28221|Deltaproteobacteria C Lantibiotic biosynthesis dehydratase C-term - - - ko:K20483 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - Lant_dehydr_C HSJS1_k127_2681195_2 379066.GAU_1376 1.06e-19 94.0 COG2070@1|root,COG2070@2|Bacteria,1ZUN8@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Nitronate monooxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO HSJS1_k127_2681195_1 1123253.AUBD01000012_gene986 1.336e-21 99.0 2ATJ5@1|root,31J35@2|Bacteria,1QGTA@1224|Proteobacteria,1TE8Y@1236|Gammaproteobacteria,1X946@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - HSJS1_k127_2681195_0 1120956.JHZK01000014_gene1747 7.698e-204 669.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JN4S@119043|Rhodobiaceae 28211|Alphaproteobacteria P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 HSJS1_k127_2696489_0 1047013.AQSP01000103_gene1162 3.672e-11 77.0 2E93F@1|root,333CD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2701065_3 745718.JADT01000014_gene128 1.986e-30 124.0 2ETTP@1|root,33MB1@2|Bacteria,4NZFX@976|Bacteroidetes,1I6T5@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - HSJS1_k127_2701065_4 240015.ACP_1619 9.58e-08 58.0 2CBGA@1|root,32RQS@2|Bacteria,3Y586@57723|Acidobacteria,2JJU2@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - HSJS1_k127_2701065_0 1267533.KB906740_gene199 2.803e-86 296.0 COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia 204432|Acidobacteriia H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf HSJS1_k127_2701065_1 1128421.JAGA01000002_gene351 5.12e-83 290.0 COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria 2|Bacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase HSJS1_k127_2701065_2 1125863.JAFN01000001_gene2168 2.38e-40 156.0 COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,42SBM@68525|delta/epsilon subdivisions,2WQ24@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox HSJS1_k127_2701065_5 509190.Cseg_2170 0.0001193 46.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2KFEW@204458|Caulobacterales 204458|Caulobacterales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG HSJS1_k127_2701754_8 331869.BAL199_04699 1.66e-25 108.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,4BP8R@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 HSJS1_k127_2701754_2 926566.Terro_3272 1.88e-149 481.0 COG0686@1|root,COG0686@2|Bacteria,3Y3Y9@57723|Acidobacteria,2JI1M@204432|Acidobacteriia 204432|Acidobacteriia E Belongs to the AlaDH PNT family - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N HSJS1_k127_2701754_10 391625.PPSIR1_24034 2.282e-09 66.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,43865@68525|delta/epsilon subdivisions,2X9Z0@28221|Deltaproteobacteria,2YVXK@29|Myxococcales 28221|Deltaproteobacteria M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin HSJS1_k127_2701754_0 1089550.ATTH01000001_gene2545 9.448e-224 708.0 COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1FIXE@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Sodium:alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp HSJS1_k127_2701754_9 671143.DAMO_2786 1.689e-16 85.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - ko:K12263 - - - - ko00000 - - - Cytochrome_CBB3,SirB HSJS1_k127_2701754_5 926569.ANT_05690 7.813e-86 293.0 COG1319@1|root,COG1319@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity - - 1.2.5.3,1.5.99.4 ko:K03519,ko:K19818 ko00760,ko01120,map00760,map01120 M00810 R02860,R07946,R11168 RC00589,RC02800 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 HSJS1_k127_2701754_6 926569.ANT_05700 5.133e-66 242.0 COG2080@1|root,COG2080@2|Bacteria,2G8E9@200795|Chloroflexi 200795|Chloroflexi C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 HSJS1_k127_2701754_4 1382306.JNIM01000001_gene1019 3.165e-119 403.0 COG0154@1|root,COG0154@2|Bacteria,2G84N@200795|Chloroflexi 200795|Chloroflexi J Amidase - - - - - - - - - - - - Amidase HSJS1_k127_2701754_3 926569.ANT_05660 2.307e-145 481.0 COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi 200795|Chloroflexi C CoA-ligase - - - ko:K02381 - - - - ko00000 - - - CoA_binding,Ligase_CoA HSJS1_k127_2701754_1 926569.ANT_05670 7.714e-175 561.0 COG0074@1|root,COG0074@2|Bacteria,2G7UI@200795|Chloroflexi 200795|Chloroflexi C Protein of unknown function (DUF1116) - - - - - - - - - - - - DUF1116 HSJS1_k127_2701754_7 247490.KSU1_D0507 4.788e-29 118.0 COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes 203682|Planctomycetes Q Multicopper oxidase - - - - - - - - - - - - - HSJS1_k127_2709673_0 1449069.JMLO01000001_gene1616 7.24e-10 63.0 COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4G1IK@85025|Nocardiaceae 201174|Actinobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K06996 - - - - ko00000 - - - Glyoxalase HSJS1_k127_2713062_1 1499967.BAYZ01000073_gene2007 5.504e-62 235.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria 2|Bacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N HSJS1_k127_2713062_4 671143.DAMO_0483 1.471e-23 115.0 COG3222@1|root,COG3222@2|Bacteria,2NRHT@2323|unclassified Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 HSJS1_k127_2713062_0 935863.AWZR01000012_gene2529 2.317e-65 246.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1X3UC@135614|Xanthomonadales 135614|Xanthomonadales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 HSJS1_k127_2713062_2 344747.PM8797T_15596 1.205e-27 115.0 2BZBR@1|root,32YH6@2|Bacteria,2J41E@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_2713062_5 309807.SRU_0241 1.096e-10 69.0 COG1141@1|root,COG1141@2|Bacteria,4PF9R@976|Bacteroidetes,1FKC0@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C 4Fe-4S single cluster domain of Ferredoxin I - - - - - - - - - - - - - HSJS1_k127_2713062_3 234267.Acid_6308 1.203e-23 115.0 COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria 57723|Acidobacteria S von Willebrand factor, type A - - - - - - - - - - - - VWA,VWA_2 HSJS1_k127_2714727_1 502025.Hoch_3071 4.44e-115 409.0 COG5184@1|root,COG5184@2|Bacteria,1PG0V@1224|Proteobacteria,4356B@68525|delta/epsilon subdivisions,2WZHG@28221|Deltaproteobacteria,2Z25P@29|Myxococcales 28221|Deltaproteobacteria DZ regulator of chromosome condensation, RCC1 - - - - - - - - - - - - - HSJS1_k127_2718978_1 745310.G432_10875 1.065e-13 84.0 COG1287@1|root,COG1287@2|Bacteria,1R184@1224|Proteobacteria,2TYYC@28211|Alphaproteobacteria,2KEPT@204457|Sphingomonadales 204457|Sphingomonadales S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 HSJS1_k127_2718978_0 1304872.JAGC01000003_gene3670 1.338e-30 141.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2M9S0@213115|Desulfovibrionales 28221|Deltaproteobacteria M Transglycosylase SLT domain mltE - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,TPR_16,TPR_6,TPR_8 HSJS1_k127_2718978_2 204669.Acid345_2692 5.677e-09 69.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - HSJS1_k127_2719201_0 1144275.COCOR_01722 1.613e-79 274.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria 1144275.COCOR_01722|- KLT protein kinase activity - - - - - - - - - - - - - HSJS1_k127_2722165_2 682795.AciX8_3194 1.24e-36 159.0 COG4591@1|root,COG4591@2|Bacteria,3Y3BU@57723|Acidobacteria,2JIC6@204432|Acidobacteriia 204432|Acidobacteriia M MacB-like periplasmic core domain - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD HSJS1_k127_2722165_4 1280954.HPO_15478 3.02e-05 55.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,43ZJT@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind,Peptidase_M10_C HSJS1_k127_2722165_3 266117.Rxyl_0725 8.698e-34 141.0 COG0287@1|root,COG4747@1|root,COG0287@2|Bacteria,COG4747@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria 84995|Rubrobacteria E Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - ACT,PDH HSJS1_k127_2722165_1 69014.TK0330 1.756e-39 160.0 COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci 183968|Thermococci E Glyoxalase-like domain - GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 HSJS1_k127_2722165_0 1463934.JOCF01000053_gene701 7.624e-41 158.0 COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria 201174|Actinobacteria E LAO AO transport system ATPase - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK HSJS1_k127_272415_1 880072.Desac_2604 7.378e-36 141.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2MS41@213462|Syntrophobacterales 28221|Deltaproteobacteria J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N HSJS1_k127_272415_2 1203606.HMPREF1526_02269 1.816e-24 104.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae 186801|Clostridia J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 HSJS1_k127_272415_3 1121920.AUAU01000017_gene1195 1.933e-16 85.0 COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria 57723|Acidobacteria J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 HSJS1_k127_272415_0 880073.Calab_2405 1.998e-154 496.0 COG3808@1|root,COG3808@2|Bacteria,2NNK9@2323|unclassified Bacteria 2|Bacteria C pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA HSJS1_k127_2730667_0 1125863.JAFN01000001_gene2270 8.081e-311 968.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW HSJS1_k127_2730667_2 644282.Deba_2866 5.981e-45 174.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM peptidase - - - - - - - - - - - - Peptidase_M23 HSJS1_k127_2730667_3 1131814.JAFO01000001_gene3172 1.496e-21 101.0 COG1937@1|root,COG1937@2|Bacteria,1N9P2@1224|Proteobacteria,2UF3F@28211|Alphaproteobacteria,3EZWC@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Metal-sensitive transcriptional repressor MA20_24475 - - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal HSJS1_k127_2730667_1 290397.Adeh_3496 1.395e-148 491.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YX0C@29|Myxococcales 28221|Deltaproteobacteria P Heavy-metal-associated domain copF - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase,YHS HSJS1_k127_273069_0 867903.ThesuDRAFT_01636 3.101e-63 229.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia 186801|Clostridia G Belongs to the glycerate kinase type-1 family - - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase HSJS1_k127_2733825_1 113355.CM001775_gene415 6.509e-25 108.0 COG3744@1|root,COG3744@2|Bacteria,1G7TY@1117|Cyanobacteria 1117|Cyanobacteria S PFAM PIN domain - - - - - - - - - - - - PIN HSJS1_k127_2733825_0 243231.GSU0302 3.236e-128 431.0 COG1916@1|root,COG1916@2|Bacteria,1R5SH@1224|Proteobacteria,42Q6N@68525|delta/epsilon subdivisions,2WKNS@28221|Deltaproteobacteria,43U80@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2751334_0 1278073.MYSTI_00845 9.311e-38 156.0 COG3055@1|root,COG3055@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria,2YYIK@29|Myxococcales 28221|Deltaproteobacteria S Domain of unknown function (DUF1929) - - - - - - - - - - - - DUF1929,Glyoxal_oxid_N,Kelch_1 HSJS1_k127_2751334_2 1348663.KCH_02450 1.851e-07 64.0 2EABA@1|root,334FH@2|Bacteria,2HY0R@201174|Actinobacteria,2M4BX@2063|Kitasatospora 201174|Actinobacteria - - - - - - - - - - - - - - TIG HSJS1_k127_2751334_1 448385.sce0534 1.733e-33 149.0 2AGGY@1|root,316PH@2|Bacteria,1PXUS@1224|Proteobacteria,43DY2@68525|delta/epsilon subdivisions,2WZ67@28221|Deltaproteobacteria,2Z1EV@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_2753553_0 105559.Nwat_2358 3.399e-36 147.0 COG5573@1|root,COG5573@2|Bacteria,1RKIK@1224|Proteobacteria,1SBYM@1236|Gammaproteobacteria,1X2IA@135613|Chromatiales 135613|Chromatiales S PIN domain - - - - - - - - - - - - PIN HSJS1_k127_2753553_1 1379270.AUXF01000002_gene1303 8.139e-13 75.0 2DR3J@1|root,33A0M@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2753553_2 1267533.KB906736_gene845 8.425e-13 72.0 COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia 204432|Acidobacteriia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran HSJS1_k127_275743_0 761193.Runsl_1400 4.348e-241 751.0 COG2368@1|root,COG2368@2|Bacteria,4NKNT@976|Bacteroidetes 976|Bacteroidetes Q 4-hydroxybutyryl-CoA dehydratase abfD - 4.2.1.120,5.3.3.3 ko:K14534 ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200 M00374,M00375 R03031,R10782 RC01857,RC03277 ko00000,ko00001,ko00002,ko01000 - - - HpaB,HpaB_N HSJS1_k127_275743_1 880073.Calab_0993 3.365e-20 97.0 COG4194@1|root,COG4194@2|Bacteria 2|Bacteria K SdpI/YhfL protein family - - - - - - - - - - - - DUF1648 HSJS1_k127_276404_1 903818.KI912268_gene3152 8.297e-102 340.0 COG1459@1|root,COG1459@2|Bacteria,3Y48Z@57723|Acidobacteria 57723|Acidobacteria NU Type II secretion system (T2SS), protein F - - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF HSJS1_k127_276404_0 204669.Acid345_1391 1.673e-162 518.0 COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia 204432|Acidobacteriia NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE HSJS1_k127_276404_2 983920.Y88_2514 2.057e-24 106.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2K14B@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD HSJS1_k127_2767464_3 573413.Spirs_0941 3.141e-54 203.0 COG3604@1|root,COG3604@2|Bacteria,2J5TK@203691|Spirochaetes 203691|Spirochaetes KT Fis Family - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,HTH_8,Sigma54_activat HSJS1_k127_2767464_6 1129794.C427_1327 1.13e-29 127.0 COG0597@1|root,COG0597@2|Bacteria,1N9NS@1224|Proteobacteria 1224|Proteobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins - - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 HSJS1_k127_2767464_0 1209989.TepiRe1_1777 0.0 1182.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran HSJS1_k127_2767464_1 945713.IALB_1544 3.398e-56 215.0 COG3240@1|root,COG3240@2|Bacteria 2|Bacteria I lipase activity - - - ko:K15349 ko05132,map05132 - - - ko00000,ko00001 - - - Lipase_GDSL,Lipase_GDSL_2 HSJS1_k127_2767464_2 1191523.MROS_2563 1.832e-54 207.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity fadL - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X HSJS1_k127_2767464_7 1173264.KI913949_gene829 8.29e-20 96.0 2DBZS@1|root,2ZC3A@2|Bacteria,1G58M@1117|Cyanobacteria,1HARD@1150|Oscillatoriales 1117|Cyanobacteria S Putative bacterial sensory transduction regulator - - - - - - - - - - - - YbjN HSJS1_k127_2767464_5 867903.ThesuDRAFT_00620 1.82e-48 178.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WD56@538999|Clostridiales incertae sedis 186801|Clostridia O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB HSJS1_k127_2767464_8 582744.Msip34_0188 1.293e-05 56.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,2KN1E@206350|Nitrosomonadales 206350|Nitrosomonadales S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 HSJS1_k127_2767464_4 335543.Sfum_1933 1.611e-48 196.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MQRW@213462|Syntrophobacterales 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 HSJS1_k127_27709_7 1499967.BAYZ01000005_gene5436 1.609e-09 68.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NQY2@2323|unclassified Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - DUF2723,PMT,PMT_2,TPR_19 HSJS1_k127_27709_6 326427.Cagg_2454 6.028e-13 80.0 COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi,3755Q@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glycos_transf_1 HSJS1_k127_27709_0 1117108.PAALTS15_06669 2.991e-100 353.0 COG0438@1|root,COG0438@2|Bacteria,1V0EK@1239|Firmicutes,4I1BH@91061|Bacilli,26UCK@186822|Paenibacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 HSJS1_k127_27709_2 383372.Rcas_0218 1.778e-79 290.0 COG0438@1|root,COG0438@2|Bacteria,2G6Z9@200795|Chloroflexi,3755I@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 HSJS1_k127_27709_4 717231.Flexsi_0125 2.836e-20 98.0 COG1399@1|root,COG1399@2|Bacteria,2GFXV@200930|Deferribacteres 200930|Deferribacteres S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 HSJS1_k127_27709_5 1047013.AQSP01000135_gene1569 6.473e-19 88.0 COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria 2|Bacteria J Ribosomal L32p protein family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p HSJS1_k127_27709_1 1121468.AUBR01000030_gene1220 1.261e-93 318.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,42F74@68295|Thermoanaerobacterales 186801|Clostridia I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis HSJS1_k127_27709_3 204669.Acid345_4573 2.667e-53 197.0 COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria,2JI6J@204432|Acidobacteriia 204432|Acidobacteriia I malonyl CoA-acyl carrier protein transacylase - - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 HSJS1_k127_2781327_1 765420.OSCT_2741 4.91e-71 256.0 COG4928@1|root,COG4928@2|Bacteria,2G9C2@200795|Chloroflexi 200795|Chloroflexi S KAP family P-loop domain - - - - - - - - - - - - KAP_NTPase HSJS1_k127_2781327_2 1283299.AUKG01000002_gene5127 1.008e-17 91.0 COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,4CR6D@84995|Rubrobacteria 84995|Rubrobacteria S CGNR zinc finger - - - - - - - - - - - - ABATE,zf-CGNR HSJS1_k127_2781327_0 1122176.KB903572_gene4836 2.58e-159 527.0 COG1361@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - CHU_C,DUF11,PKD,SprB HSJS1_k127_278474_3 1167006.UWK_02468 4.215e-80 271.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2MHMT@213118|Desulfobacterales 28221|Deltaproteobacteria O PFAM Carbamoyltransferase - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N HSJS1_k127_278474_0 1382359.JIAL01000001_gene1544 1.297e-213 684.0 COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia 204432|Acidobacteriia M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS HSJS1_k127_278474_4 1125863.JAFN01000001_gene2734 3.141e-50 189.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase HSJS1_k127_278474_2 1089553.Tph_c06700 7.429e-89 307.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,42EVZ@68295|Thermoanaerobacterales 186801|Clostridia S Required for morphogenesis under gluconeogenic growth conditions - - - - - - - - - - - - UPF0052 HSJS1_k127_278474_6 1340493.JNIF01000004_gene1010 5.312e-09 65.0 COG0457@1|root,COG0457@2|Bacteria,3Y4XQ@57723|Acidobacteria 57723|Acidobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 HSJS1_k127_278474_1 243231.GSU0099 1.905e-92 306.0 COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ADP-ribosylation factor family mglA - - ko:K06883 - - - - ko00000 - - - Arf,Ras HSJS1_k127_278474_5 398767.Glov_3123 2.972e-19 89.0 COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales 28221|Deltaproteobacteria S PFAM Roadblock LC7 family protein mglB - - - - - - - - - - - Robl_LC7 HSJS1_k127_2786260_1 306281.AJLK01000103_gene3364 6.447e-122 395.0 COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,1JJ7I@1189|Stigonemataceae 2|Bacteria C Aldo/keto reductase family - - 1.1.1.91 ko:K05882 - - - - ko00000,ko01000 - - - Aldo_ket_red HSJS1_k127_2786260_0 497964.CfE428DRAFT_0681 6.296e-137 455.0 COG2909@1|root,COG3710@1|root,COG2909@2|Bacteria,COG3710@2|Bacteria,46UY3@74201|Verrucomicrobia 74201|Verrucomicrobia K PFAM transcriptional regulator domain protein - - - - - - - - - - - - Trans_reg_C HSJS1_k127_2786260_4 472759.Nhal_2917 2.234e-34 136.0 arCOG11477@1|root,32TJG@2|Bacteria,1MYXX@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 HSJS1_k127_2786260_3 452637.Oter_3282 4.219e-43 171.0 COG2114@1|root,COG2114@2|Bacteria 2|Bacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc HSJS1_k127_2786260_7 563040.Saut_1759 7.41e-12 74.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions 1224|Proteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 HSJS1_k127_2786260_6 1304888.ATWF01000002_gene284 2.017e-15 83.0 COG1837@1|root,COG1837@2|Bacteria,2GFZI@200930|Deferribacteres 200930|Deferribacteres S KH domain - - - ko:K06960 - - - - ko00000 - - - KH_4 HSJS1_k127_2786260_5 358681.BBR47_36140 2.28e-27 119.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,26TCR@186822|Paenibacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM HSJS1_k127_2786260_2 1004785.AMBLS11_05970 8.049e-53 194.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,464K1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT HSJS1_k127_2802459_1 305900.GV64_07400 1.456e-83 282.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHXU@135619|Oceanospirillales 135619|Oceanospirillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran HSJS1_k127_2802459_3 368407.Memar_1772 6.182e-30 128.0 COG1226@1|root,arCOG01958@2157|Archaea 2157|Archaea P COG1226 Kef-type K transport systems - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N HSJS1_k127_2802459_4 1148.1653310 1.571e-29 136.0 COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1G3MK@1117|Cyanobacteria,1H64Y@1142|Synechocystis 1117|Cyanobacteria T Sigma factor PP2C-like phosphatases - - - - - - - - - - - - HAMP,HisKA,Response_reg,SpoIIE HSJS1_k127_2802459_5 1121439.dsat_0719 8.325e-29 133.0 COG4191@1|root,COG4191@2|Bacteria,1R6YZ@1224|Proteobacteria,42MXA@68525|delta/epsilon subdivisions,2WKQY@28221|Deltaproteobacteria,2M7WX@213115|Desulfovibrionales 28221|Deltaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - DUF3365,HATPase_c,HisKA,PAS_4 HSJS1_k127_2802459_0 713587.THITH_11140 0.0 1285.0 COG2133@1|root,COG2133@2|Bacteria,1R65J@1224|Proteobacteria,1RYQV@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Large extracellular alpha-helical protein - - - - - - - - - - - - - HSJS1_k127_2802459_6 662479.C440_09062 1.227e-24 119.0 COG3119@1|root,arCOG02787@2157|Archaea,2XUWX@28890|Euryarchaeota,23S64@183963|Halobacteria 183963|Halobacteria P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1,3.1.6.6 ko:K01130,ko:K01133 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase HSJS1_k127_2802459_2 1142394.PSMK_01950 2.773e-52 197.0 COG0356@1|root,COG0356@2|Bacteria,2IZP5@203682|Planctomycetes 203682|Planctomycetes C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A HSJS1_k127_2802459_9 1236514.BAKL01000034_gene2864 2.193e-15 82.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C HSJS1_k127_2802459_7 1123508.JH636439_gene886 8.083e-23 107.0 COG0711@1|root,COG0711@2|Bacteria,2J0VZ@203682|Planctomycetes 203682|Planctomycetes C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B HSJS1_k127_2802459_8 1410618.JNKI01000007_gene762 4.339e-21 100.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4H4CM@909932|Negativicutes 909932|Negativicutes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP HSJS1_k127_280679_2 329726.AM1_2759 3.608e-29 121.0 COG0457@1|root,COG0498@1|root,COG1192@1|root,COG4995@1|root,COG0457@2|Bacteria,COG0498@2|Bacteria,COG1192@2|Bacteria,COG4995@2|Bacteria,1G2KJ@1117|Cyanobacteria 1117|Cyanobacteria DE CHAT domain - - - - - - - - - - - - CHAT,NB-ARC,TIR_2,TPR_12,TPR_8 HSJS1_k127_280679_1 1142394.PSMK_05040 6.896e-45 173.0 COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes 203682|Planctomycetes K COG0454 Histone acetyltransferase HPA2 and related - - - - - - - - - - - - Acetyltransf_1 HSJS1_k127_280679_0 1396141.BATP01000014_gene2745 1.378e-76 270.0 COG0388@1|root,COG0388@2|Bacteria,46ZGG@74201|Verrucomicrobia,2IUQ5@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Carbon-nitrogen hydrolase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase HSJS1_k127_280679_3 391625.PPSIR1_16075 3.196e-15 85.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42V72@68525|delta/epsilon subdivisions,2WRHE@28221|Deltaproteobacteria,2Z1JS@29|Myxococcales 28221|Deltaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_280679_4 1047013.AQSP01000100_gene599 0.000117 55.0 COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria 2|Bacteria P COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_2809373_1 215803.DB30_2059 5.288e-62 221.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,43850@68525|delta/epsilon subdivisions,2WX9Z@28221|Deltaproteobacteria,2YWVT@29|Myxococcales 28221|Deltaproteobacteria EU Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 HSJS1_k127_2809373_0 1210884.HG799465_gene11925 3.487e-97 329.0 COG1216@1|root,COG1216@2|Bacteria,2IYBZ@203682|Planctomycetes 203682|Planctomycetes S involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_2809577_11 1229203.KI301992_gene1575 9.361e-13 74.0 COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,3UW8F@52018|unclassified Actinobacteria (class) 201174|Actinobacteria H Fumarate reductase flavoprotein C-term nadB GO:0008150,GO:0040007 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1595 FAD_binding_2,Succ_DH_flav_C HSJS1_k127_2809577_2 1192868.CAIU01000033_gene4117 1.82e-98 337.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,43J4B@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767,ko:K03813 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N HSJS1_k127_2809577_4 1121920.AUAU01000012_gene2645 5.981e-89 314.0 COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria 57723|Acidobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - - - - - - - - - - Radical_SAM HSJS1_k127_2809577_6 1254432.SCE1572_04480 1.457e-76 269.0 COG1716@1|root,COG2203@1|root,COG3829@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales 28221|Deltaproteobacteria KT Sigma-54 interaction domain - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl HSJS1_k127_2809577_10 909663.KI867150_gene1782 3.472e-23 105.0 COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria,43B9P@68525|delta/epsilon subdivisions,2X6NT@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 HSJS1_k127_2809577_8 349521.HCH_02499 7.796e-71 258.0 COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,1STV6@1236|Gammaproteobacteria,1XQTP@135619|Oceanospirillales 135619|Oceanospirillales S benzoyl-CoA oxygenase - - 1.14.13.208 ko:K15512 ko00362,map00362 - R09555 RC01739 ko00000,ko00001,ko01000 - - - - HSJS1_k127_2809577_3 266117.Rxyl_2923 3.178e-91 315.0 COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4CQPH@84995|Rubrobacteria 84995|Rubrobacteria E Proline dehydrogenase - - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh HSJS1_k127_2809577_5 204669.Acid345_1478 9.286e-88 298.0 COG0345@1|root,COG0345@2|Bacteria,3Y41B@57723|Acidobacteria,2JITZ@204432|Acidobacteriia 204432|Acidobacteriia E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer HSJS1_k127_2809577_9 1278073.MYSTI_03895 4.718e-61 225.0 COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SA7@68525|delta/epsilon subdivisions,2WNRU@28221|Deltaproteobacteria,2YU91@29|Myxococcales 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - FHA,GGDEF,Yop-YscD_cpl HSJS1_k127_2809577_7 706587.Desti_3921 9.382e-74 256.0 COG2080@1|root,COG2080@2|Bacteria,1MY3F@1224|Proteobacteria,43AMR@68525|delta/epsilon subdivisions,2X61U@28221|Deltaproteobacteria,2MRMX@213462|Syntrophobacterales 28221|Deltaproteobacteria C 2Fe-2S -binding domain - - - ko:K13483 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002 - - - Fer2,Fer2_2 HSJS1_k127_2809577_0 706587.Desti_3922 0.0 1058.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MR87@213462|Syntrophobacterales 28221|Deltaproteobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2 HSJS1_k127_2809577_1 335543.Sfum_2511 5.081e-121 396.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2MQZF@213462|Syntrophobacterales 28221|Deltaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 HSJS1_k127_2818850_0 1047013.AQSP01000067_gene2202 5.256e-20 91.0 2EQW9@1|root,33IG2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2818850_1 502025.Hoch_2288 9.793e-19 97.0 2DZX2@1|root,32VM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_2818850_2 593117.TGAM_0375 3.513e-17 88.0 arCOG07813@1|root,arCOG07813@2157|Archaea 2157|Archaea C LamG domain protein jellyroll fold domain protein - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3 HSJS1_k127_2818850_4 562970.Btus_3037 9.253e-11 65.0 28W7I@1|root,2ZI85@2|Bacteria,1W3V1@1239|Firmicutes,4I13M@91061|Bacilli,27AJJ@186823|Alicyclobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - HSJS1_k127_2818850_3 546271.Selsp_0283 1.113e-13 78.0 COG2026@1|root,COG2026@2|Bacteria,1VNY8@1239|Firmicutes 1239|Firmicutes DJ Plasmid stabilization system - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin HSJS1_k127_2824767_8 1121405.dsmv_0325 9.192e-06 58.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2MHRK@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM peptidase - - - - - - - - - - - iAF987.Gmet_1238 Peptidase_M48,TPR_14,TPR_16,TPR_19 HSJS1_k127_2824767_1 1124780.ANNU01000051_gene2100 6.521e-78 276.0 COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,47KW4@768503|Cytophagia 976|Bacteroidetes EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 HSJS1_k127_2824767_6 666684.AfiDRAFT_2403 2.004e-06 59.0 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RJG9@1224|Proteobacteria,2TUDE@28211|Alphaproteobacteria,3JSPJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Helix-turn-helix XRE-family like proteins MA20_09785 - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 HSJS1_k127_2824767_5 1279009.ADICEAN_01893 1.686e-09 68.0 COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,47PPQ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_21,TPR_6,TPR_7,TPR_8 HSJS1_k127_2824767_0 861299.J421_2719 5.957e-88 316.0 COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Pyrimidine nucleoside phosphorylase C-terminal domain - - 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C HSJS1_k127_2824767_4 1047013.AQSP01000144_gene872 1.314e-19 103.0 COG1470@1|root,COG2755@1|root,COG1470@2|Bacteria,COG2755@2|Bacteria,2NRYN@2323|unclassified Bacteria 2|Bacteria E GDSL-like Lipase/Acylhydrolase family - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CBM_20,DUF1796,F5_F8_type_C,Lipase_GDSL_2 HSJS1_k127_2824767_7 1278073.MYSTI_07308 2.304e-06 59.0 COG3291@1|root,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria 1224|Proteobacteria DZ repeat protein - - - - - - - - - - - - Big_5 HSJS1_k127_2824767_3 240015.ACP_3409 1.784e-20 95.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria,2JHTM@204432|Acidobacteriia 204432|Acidobacteriia S Belongs to the CinA family - - 3.5.1.42 ko:K03742 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth HSJS1_k127_2828424_2 330214.NIDE0518 2.323e-17 91.0 COG2802@1|root,COG2802@2|Bacteria,3J13Q@40117|Nitrospirae 40117|Nitrospirae S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg HSJS1_k127_2828424_1 562970.Btus_2993 1.034e-68 248.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,277WF@186823|Alicyclobacillaceae 91061|Bacilli S PFAM metal-dependent phosphohydrolase HD sub domain - - - ko:K06885 - - - - ko00000 - - - HD HSJS1_k127_2828424_0 1121104.AQXH01000003_gene384 1.301e-125 412.0 COG2421@1|root,COG2421@2|Bacteria,4NKD7@976|Bacteroidetes 976|Bacteroidetes C Acetamidase/Formamidase family - - - - - - - - - - - - FmdA_AmdA HSJS1_k127_2829015_2 935863.AWZR01000009_gene36 2.247e-29 126.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1X3IV@135614|Xanthomonadales 135614|Xanthomonadales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M HSJS1_k127_2829015_0 414684.RC1_0616 2.279e-126 417.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2JQ3T@204441|Rhodospirillales 204441|Rhodospirillales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 HSJS1_k127_2829015_1 290397.Adeh_3769 1.123e-37 161.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2YU89@29|Myxococcales 28221|Deltaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8 HSJS1_k127_2829345_0 644968.DFW101_3581 0.0 1158.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WJF3@28221|Deltaproteobacteria,2M98U@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM alpha-2-macroglobulin domain protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl HSJS1_k127_2829345_3 670487.Ocepr_0464 4.446e-31 125.0 COG1146@1|root,COG1146@2|Bacteria,1WKCK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Ferredoxin - - - - - - - - - - - - Fer4 HSJS1_k127_2829345_1 1191523.MROS_1191 2.439e-88 302.0 COG0668@1|root,COG0668@2|Bacteria 2|Bacteria M transmembrane transport - - - - - - - - - - - - MS_channel HSJS1_k127_2829345_2 1123400.KB904759_gene2068 1.91e-45 172.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4605T@72273|Thiotrichales 72273|Thiotrichales O molecular chaperone - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C HSJS1_k127_2835157_2 1125863.JAFN01000001_gene2452 4.434e-40 155.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42W8P@68525|delta/epsilon subdivisions,2WRV4@28221|Deltaproteobacteria 28221|Deltaproteobacteria L PFAM NUDIX hydrolase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX HSJS1_k127_2835157_4 47763.JNZA01000002_gene3265 2.489e-05 57.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator, SARP family - - - - - - - - - - - - BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C HSJS1_k127_2835157_5 572477.Alvin_2628 9.476e-05 53.0 28MUS@1|root,2ZB2I@2|Bacteria,1N8T7@1224|Proteobacteria,1RZI3@1236|Gammaproteobacteria,1WXS4@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4412) - - - - - - - - - - - - DUF4412 HSJS1_k127_2835157_3 357808.RoseRS_0032 2.367e-30 139.0 COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3753Y@32061|Chloroflexia 32061|Chloroflexia KT PFAM Stage II sporulation E family protein - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - SpoIIE HSJS1_k127_2835157_0 1089547.KB913013_gene1508 1.682e-48 197.0 COG0739@1|root,COG0739@2|Bacteria,4NIQN@976|Bacteroidetes,47JX9@768503|Cytophagia 976|Bacteroidetes M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 HSJS1_k127_2835157_1 694427.Palpr_2132 1.92e-42 171.0 COG0641@1|root,COG0641@2|Bacteria 2|Bacteria C radical SAM - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM HSJS1_k127_2840692_1 251221.35210998 1.597e-72 271.0 COG0842@1|root,COG0842@2|Bacteria 2|Bacteria V Transport permease protein - - - - - - - - - - - - - HSJS1_k127_2840692_0 251221.35210997 2.235e-110 363.0 COG1131@1|root,COG1131@2|Bacteria,1G0BQ@1117|Cyanobacteria 1117|Cyanobacteria V ABC transporter - - - - - - - - - - - - ABC_tran HSJS1_k127_2848922_3 197221.22296018 1.333e-09 64.0 COG5505@1|root,COG5505@2|Bacteria,1G9X6@1117|Cyanobacteria 1117|Cyanobacteria S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 HSJS1_k127_2848922_2 1267535.KB906767_gene5461 2.943e-35 143.0 COG3682@1|root,COG3682@2|Bacteria,3Y8CR@57723|Acidobacteria,2JN9Z@204432|Acidobacteriia 204432|Acidobacteriia K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R HSJS1_k127_2848922_1 682795.AciX8_0882 5.701e-42 170.0 COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria,2JKFK@204432|Acidobacteriia 204432|Acidobacteriia KT BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M56 HSJS1_k127_2848922_0 1123368.AUIS01000006_gene572 1.662e-66 234.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,2NCEE@225057|Acidithiobacillales 225057|Acidithiobacillales S SOS response associated peptidase (SRAP) - - - - - - - - - - - - SRAP HSJS1_k127_2858867_5 1158338.JNLJ01000001_gene932 7.047e-09 67.0 COG1826@1|root,COG1826@2|Bacteria,2G4BU@200783|Aquificae 200783|Aquificae U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 HSJS1_k127_2858867_4 397945.Aave_4765 1.674e-24 117.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,4AC60@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM Aminoglycoside phosphotransferase - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH HSJS1_k127_2858867_0 290397.Adeh_3151 3.167e-170 545.0 COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,42Z8C@68525|delta/epsilon subdivisions,2WU08@28221|Deltaproteobacteria,2YXJP@29|Myxococcales 28221|Deltaproteobacteria C Cytochrome c - - - - - - - - - - - - - HSJS1_k127_2858867_2 1267535.KB906767_gene2778 5.569e-54 199.0 COG1595@1|root,COG1595@2|Bacteria,3Y7S5@57723|Acidobacteria,2JMWY@204432|Acidobacteriia 204432|Acidobacteriia K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_2858867_3 1267535.KB906767_gene2777 9.292e-31 126.0 2BVXR@1|root,32QYG@2|Bacteria,3Y86A@57723|Acidobacteria 57723|Acidobacteria S DoxX - - - - - - - - - - - - DoxX HSJS1_k127_2858867_1 99598.Cal7507_3979 2.574e-57 209.0 COG0500@1|root,COG2226@2|Bacteria,1GCAE@1117|Cyanobacteria,1HQK1@1161|Nostocales 1117|Cyanobacteria H PFAM Methyltransferase - - - - - - - - - - - - Methyltransf_11 HSJS1_k127_2869199_3 338966.Ppro_0527 2.013e-14 76.0 COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,43T6Q@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA HSJS1_k127_2869199_2 340.xcc-b100_1882 3.039e-42 168.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1X5HS@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - ko:K09973 - - - - ko00000 - - - TraB HSJS1_k127_2869199_1 756272.Plabr_4030 9.007e-52 187.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family ywlC1 - - - - - - - - - - - DinB_2 HSJS1_k127_2869199_0 443144.GM21_0487 8.98e-82 291.0 COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales 28221|Deltaproteobacteria D Phage integrase, N-terminal SAM-like domain xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase HSJS1_k127_2869708_1 1185876.BN8_00757 5.505e-138 441.0 COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,47K7D@768503|Cytophagia 976|Bacteroidetes P esterase - - - - - - - - - - - - Esterase HSJS1_k127_2869708_0 290397.Adeh_2406 3.881e-222 711.0 COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales 28221|Deltaproteobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4,Fer4_20,Pyr_redox_2 HSJS1_k127_2879539_3 1111479.AXAR01000003_gene1610 1.21e-49 199.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,278YD@186823|Alicyclobacillaceae 91061|Bacilli H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC HSJS1_k127_2879539_2 1232410.KI421412_gene411 1.673e-76 274.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH HSJS1_k127_2879539_5 204669.Acid345_0749 4.154e-14 82.0 COG0755@1|root,COG0755@2|Bacteria,3Y3QF@57723|Acidobacteria 57723|Acidobacteria O PFAM Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm HSJS1_k127_2879539_1 246197.MXAN_2618 1.499e-129 428.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2YUGA@29|Myxococcales 28221|Deltaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt HSJS1_k127_2879539_4 331869.BAL199_22122 1.424e-42 162.0 COG3818@1|root,COG3818@2|Bacteria,1RG7T@1224|Proteobacteria,2U8S8@28211|Alphaproteobacteria,4BSHP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Acetyltransferase (GNAT) domain - - - ko:K06977 - - - - ko00000 - - - Acetyltransf_1 HSJS1_k127_2879539_0 867845.KI911784_gene130 4.357e-258 820.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,37589@32061|Chloroflexia 32061|Chloroflexia E glutamate synthase, alpha subunit domain protein - - 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase HSJS1_k127_2892484_2 1249975.JQLP01000005_gene2506 2.471e-61 231.0 COG1357@1|root,COG1361@1|root,COG1520@1|root,COG2304@1|root,COG2911@1|root,COG1357@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,4NMB8@976|Bacteroidetes,1IJKA@117743|Flavobacteriia 976|Bacteroidetes M Pfam C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,HYR,SdrD_B HSJS1_k127_2892484_5 1304865.JAGF01000001_gene119 6.733e-10 72.0 COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria 201174|Actinobacteria P PFAM PKD domain containing protein - - - - - - - - - - - - Metallophos,PKD HSJS1_k127_2892484_0 1089550.ATTH01000001_gene1831 1.034e-130 449.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_2892484_3 1267534.KB906757_gene1063 1.656e-32 132.0 COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia 204432|Acidobacteriia K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_2892484_1 309800.C498_01035 8.671e-78 281.0 COG0520@1|root,arCOG00065@2157|Archaea,2XYKY@28890|Euryarchaeota,23ZYZ@183963|Halobacteria 183963|Halobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 HSJS1_k127_2892484_4 118168.MC7420_1677 2.017e-20 96.0 COG1335@1|root,COG1335@2|Bacteria,1GAHK@1117|Cyanobacteria 1117|Cyanobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase HSJS1_k127_2900657_0 344747.PM8797T_03214 8.726e-98 334.0 COG1502@1|root,COG1502@2|Bacteria,2IYFI@203682|Planctomycetes 203682|Planctomycetes I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N HSJS1_k127_2900657_1 398525.KB900701_gene1105 2.666e-50 182.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_6,DLH,Thioesterase HSJS1_k127_2901275_1 1385513.N780_13880 3.33e-117 396.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,2Y8Z1@289201|Pontibacillus 91061|Bacilli I Acyl-CoA dehydrogenase mmgC - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_2901275_0 404589.Anae109_2136 1.289e-133 437.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales 28221|Deltaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_2901275_2 251229.Chro_4618 1.734e-57 219.0 28N8A@1|root,2ZBCR@2|Bacteria,1G2Q6@1117|Cyanobacteria,3VMJF@52604|Pleurocapsales 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_2901275_3 861299.J421_0916 1.868e-49 197.0 COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Insulinase (Peptidase family M16) - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_2915422_0 883126.HMPREF9710_00101 1.42e-55 215.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VH5K@28216|Betaproteobacteria,4768D@75682|Oxalobacteraceae 28216|Betaproteobacteria KLT RIO1 family prkC2 - 2.7.11.1,3.1.3.16 ko:K01090,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PP2C_2,Pkinase,TPR_16,TPR_19 HSJS1_k127_2915422_1 937777.Deipe_0437 3.071e-05 57.0 COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,1WISP@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PQQ_2,PQQ_3,Pkinase HSJS1_k127_2918956_1 487796.Flav2ADRAFT_1528 3.836e-25 108.0 COG1366@1|root,COG1366@2|Bacteria 2|Bacteria T antisigma factor binding - - - - - - - - - - - - STAS HSJS1_k127_2918956_2 487796.Flav2ADRAFT_1527 9.598e-22 102.0 COG2172@1|root,COG2172@2|Bacteria 2|Bacteria T sigma factor antagonist activity - - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 HSJS1_k127_2918956_0 756272.Plabr_2759 8.711e-63 224.0 COG1716@1|root,COG2203@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,2IY6A@203682|Planctomycetes 203682|Planctomycetes T Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - FHA,GAF,GAF_2,HTH_8,Sigma54_activat HSJS1_k127_2921572_0 1163409.UUA_09631 1.098e-128 419.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RN94@1236|Gammaproteobacteria,1X8WG@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF3641) - - - - - - - - - - - - DUF3641,Radical_SAM HSJS1_k127_2921572_1 161934.XP_010685199.1 1.766e-05 55.0 KOG4539@1|root,KOG4539@2759|Eukaryota,37NM2@33090|Viridiplantae,3GBWB@35493|Streptophyta 35493|Streptophyta S Mitochondrial K+-H+ exchange-related - - - - - - - - - - - - Mit_KHE1 HSJS1_k127_2921626_4 756499.Desde_3893 7.993e-11 73.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae 186801|Clostridia C electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha,Fer4 HSJS1_k127_2921626_2 985053.VMUT_0382 6.717e-39 155.0 COG2086@1|root,arCOG00446@2157|Archaea,2XS2H@28889|Crenarchaeota 28889|Crenarchaeota C Electron transfer flavoprotein domain - - - ko:K03521 - - - - ko00000 - - - ETF HSJS1_k127_2921626_1 292459.STH623 6.581e-105 366.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia 186801|Clostridia C Fe-S oxidoreductase - - - - - - - - - - - - CCG,Fer4_8,Nitrate_red_gam HSJS1_k127_2921626_0 1097668.BYI23_C006270 1.065e-198 627.0 COG1960@1|root,COG1960@2|Bacteria,1R45D@1224|Proteobacteria,2VQ86@28216|Betaproteobacteria,1KCN9@119060|Burkholderiaceae 28216|Betaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_2921626_3 487521.OCU_00990 8.731e-16 88.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,236D8@1762|Mycobacteriaceae 201174|Actinobacteria T helix_turn_helix, cAMP Regulatory protein glxR GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding HSJS1_k127_2923196_1 1031288.AXAA01000020_gene1195 5.561e-64 226.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,36EI0@31979|Clostridiaceae 186801|Clostridia F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS HSJS1_k127_2923196_0 1278073.MYSTI_05133 2.8e-95 325.0 COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,42XHB@68525|delta/epsilon subdivisions,2WSKY@28221|Deltaproteobacteria,2YVC2@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 HSJS1_k127_2923196_2 262724.TT_P0068 1.394e-08 60.0 COG1708@1|root,COG1708@2|Bacteria,1WKG4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Nucleotidyltransferase domain - - - ko:K07076 - - - - ko00000 - - - NTP_transf_2 HSJS1_k127_2925748_3 1429851.X548_02615 0.0003798 44.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SH3N@1236|Gammaproteobacteria,1X4NY@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - SPOR HSJS1_k127_2925748_1 502025.Hoch_2921 2.645e-52 201.0 COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X39N@28221|Deltaproteobacteria,2Z0CB@29|Myxococcales 28221|Deltaproteobacteria L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp HSJS1_k127_2925748_0 401053.AciPR4_1562 5.937e-198 633.0 COG1858@1|root,COG1858@2|Bacteria,3Y58I@57723|Acidobacteria,2JKKG@204432|Acidobacteriia 204432|Acidobacteriia P cytochrome C peroxidase - - - - - - - - - - - - - HSJS1_k127_2925748_2 401053.AciPR4_1561 7.182e-46 171.0 COG2010@1|root,COG2010@2|Bacteria,3Y7PW@57723|Acidobacteria,2JMW5@204432|Acidobacteriia 204432|Acidobacteriia C Cytochrome c - - - - - - - - - - - - - HSJS1_k127_2927611_3 1124780.ANNU01000008_gene2736 3.26e-13 78.0 COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,47JDG@768503|Cytophagia 976|Bacteroidetes Q methyltransferase - - - - - - - - - - - - GT87 HSJS1_k127_2927611_0 1267533.KB906733_gene3096 1.013e-156 509.0 COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia 204432|Acidobacteriia M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3 HSJS1_k127_2927611_2 867903.ThesuDRAFT_01120 1.292e-19 96.0 COG1670@1|root,COG1670@2|Bacteria,1V2FI@1239|Firmicutes,25B0M@186801|Clostridia,3WDSJ@538999|Clostridiales incertae sedis 186801|Clostridia J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 HSJS1_k127_2927611_1 926550.CLDAP_09070 3.638e-59 224.0 COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi 200795|Chloroflexi EQ PFAM peptidase S58, DmpA - - - - - - - - - - - - Peptidase_S58 HSJS1_k127_2928461_3 411467.BACCAP_04464 7.326e-23 100.0 2EPJ6@1|root,33H5U@2|Bacteria 2|Bacteria S Unextendable partial coding region - - - - - - - - - - - - - HSJS1_k127_2928461_0 1121104.AQXH01000001_gene2056 5.05e-315 981.0 COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1IUUS@117747|Sphingobacteriia 976|Bacteroidetes E Amino acid permease - - - - - - - - - - - - AA_permease,SLC12 HSJS1_k127_2928461_1 1123399.AQVE01000023_gene441 1.509e-149 488.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfkA GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003872,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005945,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019200,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0042802,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0061615,GO:0061695,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494,GO:1990234 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iNRG857_1313.NRG857_19550 PFK HSJS1_k127_2928461_2 1267533.KB906738_gene2261 4.506e-136 443.0 COG0534@1|root,COG0534@2|Bacteria,3Y6HQ@57723|Acidobacteria,2JNI9@204432|Acidobacteriia 204432|Acidobacteriia V MatE - - - - - - - - - - - - MatE HSJS1_k127_2932147_1 1521187.JPIM01000026_gene1162 3.817e-85 288.0 COG1136@1|root,COG1136@2|Bacteria,2G8HT@200795|Chloroflexi,375FM@32061|Chloroflexia 32061|Chloroflexia V PFAM ABC transporter related - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_2932147_0 383372.Rcas_1858 8.074e-244 790.0 COG0577@1|root,COG0577@2|Bacteria,2G6IW@200795|Chloroflexi,374ZQ@32061|Chloroflexia 32061|Chloroflexia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_2932147_2 383372.Rcas_0002 4.325e-72 254.0 COG5621@1|root,COG5621@2|Bacteria,2G6EI@200795|Chloroflexi,374YJ@32061|Chloroflexia 32061|Chloroflexia S Lipocalin-like domain - - - - - - - - - - - - CrtC,Lipocalin_9 HSJS1_k127_2933001_3 247490.KSU1_D0896 2.031e-17 83.0 COG1215@1|root,COG1215@2|Bacteria,2IXXE@203682|Planctomycetes 203682|Planctomycetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_2933001_0 330214.NIDE0344 1.857e-106 353.0 COG0714@1|root,COG0714@2|Bacteria,3J0WQ@40117|Nitrospirae 40117|Nitrospirae S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 HSJS1_k127_2933001_2 330214.NIDE0343 4.367e-38 164.0 COG1721@1|root,COG1721@2|Bacteria 2|Bacteria E protein (some members contain a von Willebrand factor type A (vWA) domain - - - - - - - - - - - - DUF58 HSJS1_k127_2933001_1 321327.CYA_0782 6.11e-39 168.0 COG1305@1|root,COG1305@2|Bacteria,1FZW2@1117|Cyanobacteria,1GZT0@1129|Synechococcus 1117|Cyanobacteria E Transglutaminase/protease-like homologues - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core HSJS1_k127_2937719_0 616991.JPOO01000003_gene1700 1.991e-155 494.0 COG1140@1|root,COG1140@2|Bacteria 2|Bacteria C nitrate reductase beta subunit narH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189 Fer4_11,Nitr_red_bet_C HSJS1_k127_2937719_1 1121920.AUAU01000008_gene1619 7.886e-102 334.0 COG5013@1|root,COG5013@2|Bacteria 2|Bacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370,ko:K17050 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000,ko02000 5.A.3.1,5.A.3.8 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N HSJS1_k127_2941589_0 118161.KB235922_gene575 1.264e-17 92.0 COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria 1117|Cyanobacteria P Arylsulfatase a - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - DUF4976,Sulfatase,Sulfatase_C HSJS1_k127_295802_3 472759.Nhal_0438 1.361e-63 226.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1WWNF@135613|Chromatiales 135613|Chromatiales I Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase HSJS1_k127_295802_0 886293.Sinac_5560 2.82e-134 444.0 COG0612@1|root,COG0612@2|Bacteria 2|Bacteria L Peptidase, M16 ymxG - - ko:K07263,ko:K07623 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_295802_1 886293.Sinac_5561 1.258e-132 437.0 COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes 203682|Planctomycetes S PFAM Peptidase M16 inactive domain - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_295802_2 1125863.JAFN01000001_gene809 1.3e-94 329.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PDZ DHR GLGF domain protein - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 HSJS1_k127_2960163_0 1173028.ANKO01000164_gene2746 1.317e-277 865.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1H6Y0@1150|Oscillatoriales 1117|Cyanobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P HSJS1_k127_2965795_1 583355.Caka_1333 7.339e-79 276.0 COG1600@1|root,COG1600@2|Bacteria,46TWX@74201|Verrucomicrobia,3K7UK@414999|Opitutae 414999|Opitutae C 4Fe-4S double cluster binding domain - - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 HSJS1_k127_2965795_0 986075.CathTA2_1043 1.456e-98 336.0 COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N HSJS1_k127_2970073_0 1173028.ANKO01000244_gene3949 1.904e-86 297.0 COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales 1117|Cyanobacteria S Phenazine biosynthesis protein - - - - - - - - - - - - PhzC-PhzF HSJS1_k127_2970073_1 1183438.GKIL_2151 1.354e-68 251.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1,Amidohydro_3 HSJS1_k127_297079_1 525897.Dbac_1034 3.648e-11 75.0 2CI8B@1|root,334QN@2|Bacteria,1NX7P@1224|Proteobacteria,430WI@68525|delta/epsilon subdivisions,2WVZA@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_297079_0 234267.Acid_6465 4.402e-20 98.0 COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria 57723|Acidobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug HSJS1_k127_2974029_0 671143.DAMO_0098 9.424e-103 358.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec HSJS1_k127_2974029_1 243231.GSU0227 8.426e-62 225.0 COG0270@1|root,COG0270@2|Bacteria,1PZ0N@1224|Proteobacteria,42YYZ@68525|delta/epsilon subdivisions 1224|Proteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase HSJS1_k127_2974230_0 671143.DAMO_1287 4.278e-116 386.0 COG2801@1|root,COG2801@2|Bacteria,2NQ4I@2323|unclassified Bacteria 2|Bacteria L Homeodomain-like domain - - - ko:K07497 - - - - ko00000 - - - HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3 HSJS1_k127_2974230_2 449447.MAE_07660 3.768e-14 75.0 2EDJW@1|root,33I1G@2|Bacteria,1GB0Y@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_2974230_1 1380390.JIAT01000010_gene4774 2.866e-29 127.0 COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,4CR6D@84995|Rubrobacteria 84995|Rubrobacteria S CGNR zinc finger - - - - - - - - - - - - ABATE,zf-CGNR HSJS1_k127_2975637_19 448385.sce0864 3.723e-05 55.0 COG2133@1|root,COG2133@2|Bacteria,1R0BJ@1224|Proteobacteria,43CTV@68525|delta/epsilon subdivisions,2X65J@28221|Deltaproteobacteria,2YUDI@29|Myxococcales 28221|Deltaproteobacteria C pyrroloquinoline quinone binding - - - - - - - - - - - - - HSJS1_k127_2975637_17 572479.Hprae_0381 1.211e-05 57.0 COG0664@1|root,COG0664@2|Bacteria,1V7HD@1239|Firmicutes,24K0K@186801|Clostridia 186801|Clostridia K - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding HSJS1_k127_2975637_16 504728.K649_02630 3.749e-10 62.0 COG5450@1|root,COG5450@2|Bacteria 2|Bacteria K positive regulation of growth - - - - - - - - - - - - VapB_antitoxin HSJS1_k127_2975637_15 643648.Slip_2134 1.172e-10 68.0 COG1487@1|root,COG1487@2|Bacteria,1UEGK@1239|Firmicutes,25JDH@186801|Clostridia,42KUG@68298|Syntrophomonadaceae 186801|Clostridia S PIN domain - - - - - - - - - - - - PIN HSJS1_k127_2975637_14 745776.DGo_CA1980 3.582e-14 85.0 2D62R@1|root,32TKD@2|Bacteria 2|Bacteria S TIR domain - - - - - - - - - - - - TIR_2 HSJS1_k127_2975637_12 8090.ENSORLP00000004368 7.245e-17 94.0 KOG4059@1|root,KOG4059@2759|Eukaryota,3A621@33154|Opisthokonta,3BSXB@33208|Metazoa,3CWA1@33213|Bilateria,47ZBD@7711|Chordata,498BY@7742|Vertebrata,4A330@7898|Actinopterygii 33208|Metazoa S Gamma-glutamyl cyclotransferase b GGCT GO:0001836,GO:0002376,GO:0003674,GO:0003824,GO:0003839,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007599,GO:0008150,GO:0008152,GO:0008219,GO:0008637,GO:0009058,GO:0009611,GO:0009987,GO:0012501,GO:0016043,GO:0016829,GO:0016840,GO:0016842,GO:0019184,GO:0023052,GO:0032501,GO:0034641,GO:0042060,GO:0042381,GO:0042398,GO:0042802,GO:0042803,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0045087,GO:0046983,GO:0050789,GO:0050794,GO:0050817,GO:0050878,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097190,GO:1901564,GO:1901566,GO:1901576 4.3.2.9 ko:K00682 ko00480,map00480 - R02743,R03749 RC00064,RC00777 ko00000,ko00001,ko01000 - - - AIG2_2 HSJS1_k127_2975637_0 644966.Tmar_0901 7.096e-208 672.0 COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis 186801|Clostridia C TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig HSJS1_k127_2975637_9 1238182.C882_2581 4.755e-39 156.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2TT5I@28211|Alphaproteobacteria,2JYT6@204441|Rhodospirillales 204441|Rhodospirillales I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat HSJS1_k127_2975637_2 1260251.SPISAL_02110 3.263e-136 441.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N HSJS1_k127_2975637_8 243231.GSU1076 1.201e-42 177.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,43U6G@69541|Desulfuromonadales 28221|Deltaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N HSJS1_k127_2975637_4 448385.sce7598 3.109e-84 296.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YY2Q@29|Myxococcales 28221|Deltaproteobacteria H Cys/Met metabolism PLP-dependent enzyme - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP HSJS1_k127_2975637_6 1125863.JAFN01000001_gene2568 1.996e-72 278.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria 28221|Deltaproteobacteria O peptidyl-prolyl isomerase nifM - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 HSJS1_k127_2975637_13 991905.SL003B_3563 1.672e-16 93.0 COG4254@1|root,COG4254@2|Bacteria,1PPWK@1224|Proteobacteria,2TYY3@28211|Alphaproteobacteria,4BRH4@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S FecR protein - - - - - - - - - - - - FecR,LysM HSJS1_k127_2975637_1 401053.AciPR4_0872 1.769e-164 525.0 COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia 204432|Acidobacteriia D cell shape determining protein MreB - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl HSJS1_k127_2975637_10 671143.DAMO_3132 4.925e-31 140.0 COG1792@1|root,COG1792@2|Bacteria,2NPNX@2323|unclassified Bacteria 2|Bacteria M Cell shape-determining protein MreC mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC HSJS1_k127_2975637_3 177437.HRM2_35240 7.114e-126 424.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales 28221|Deltaproteobacteria M Penicillin-binding Protein dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0928 PBP_dimer,Transpeptidase HSJS1_k127_2975637_5 1047013.AQSP01000071_gene1934 1.094e-73 265.0 COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria 2|Bacteria D Peptidoglycan polymerase that is essential for cell wall elongation rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE HSJS1_k127_2975637_7 1499967.BAYZ01000029_gene1223 2.794e-68 243.0 COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria 2|Bacteria J Ribonuclease E/G family rng GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 HSJS1_k127_2977114_3 1313421.JHBV01000014_gene3818 0.0001356 48.0 COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CHU_C,LRR_5,PKD,SprB HSJS1_k127_2977114_0 1267535.KB906767_gene870 1.036e-43 186.0 COG3209@1|root,COG3209@2|Bacteria,3Y7FC@57723|Acidobacteria,2JKK9@204432|Acidobacteriia 204432|Acidobacteriia M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat HSJS1_k127_2977114_1 452637.Oter_2184 6.912e-28 133.0 COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae 2|Bacteria S SMART Immunoglobulin C2 type - - - - - - - - - - - - DUF5122,He_PIG,Ig_3,VCBS HSJS1_k127_2977114_2 1246995.AFR_40880 1.314e-09 73.0 COG1361@1|root,COG2304@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,2I8F1@201174|Actinobacteria,4DFBB@85008|Micromonosporales 201174|Actinobacteria M Conserved repeat domain - - - - - - - - - - - - DUF11,DUF3344 HSJS1_k127_2977341_4 1396141.BATP01000034_gene4151 4.104e-22 102.0 COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity MA20_01585 - - ko:K01173 ko04210,map04210 - - - ko00000,ko00001,ko03029 - - - Glu_cyclase_2,PQQ_2 HSJS1_k127_2977341_2 1047013.AQSP01000111_gene1662 2.644e-64 232.0 COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 HSJS1_k127_2977341_1 1379698.RBG1_1C00001G0508 2.644e-122 404.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family bktB - 2.3.1.16,2.3.1.9 ko:K00626,ko:K07508 ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00085,M00087,M00088,M00095,M00373,M00374,M00375 R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747 RC00004,RC00326,RC00405,RC01702 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N HSJS1_k127_2977341_6 1173027.Mic7113_1923 2.535e-11 74.0 COG0265@1|root,COG0265@2|Bacteria,1G0XN@1117|Cyanobacteria,1H8PC@1150|Oscillatoriales 1117|Cyanobacteria O COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PPC,Trypsin_2 HSJS1_k127_2977341_5 448385.sce4475 5.972e-14 77.0 COG3215@1|root,COG3215@2|Bacteria,1QR4G@1224|Proteobacteria,4352F@68525|delta/epsilon subdivisions,2WZDD@28221|Deltaproteobacteria,2Z1W5@29|Myxococcales 28221|Deltaproteobacteria NU PilZ domain - - - - - - - - - - - - PilZ HSJS1_k127_2977341_3 497965.Cyan7822_0312 8.892e-42 159.0 COG0824@1|root,COG0824@2|Bacteria,1GDHP@1117|Cyanobacteria 1117|Cyanobacteria S Thioesterase-like superfamily - - - ko:K15315 ko01059,map01059 - R11436 RC00039,RC03437 ko00000,ko00001,ko01008 - - - 4HBT_2 HSJS1_k127_2977341_0 28072.Nos7524_5243 0.0 1164.0 COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1G1IB@1117|Cyanobacteria,1HJKD@1161|Nostocales 2|Bacteria IQ TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA - - - ko:K15314 ko01059,ko01130,map01059,map01130 M00824,M00825 R11435 - ko00000,ko00001,ko00002,ko01008 - - - Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HSJS1_k127_2977861_3 1267535.KB906767_gene3061 1.212e-07 58.0 2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - HSJS1_k127_2977861_1 404589.Anae109_1348 8.814e-34 144.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,2YVSW@29|Myxococcales 28221|Deltaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) tenI GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI HSJS1_k127_2977861_2 631362.Thi970DRAFT_01554 1.776e-30 134.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1WY9G@135613|Chromatiales 135613|Chromatiales MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 HSJS1_k127_2977861_0 671143.DAMO_3138 2.515e-49 193.0 COG0564@1|root,COG0564@2|Bacteria,2NNY5@2323|unclassified Bacteria 2|Bacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 HSJS1_k127_2978195_3 765912.Thimo_3445 3.597e-25 116.0 COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales 135613|Chromatiales F other phosphorylase family 1 - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 HSJS1_k127_2978195_0 1121406.JAEX01000005_gene2990 2.317e-258 817.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2M92I@213115|Desulfovibrionales 28221|Deltaproteobacteria O ATP-dependent Clp protease ATP-binding subunit ClpA clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N HSJS1_k127_2978195_2 1192034.CAP_3461 2.003e-29 121.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2YVP9@29|Myxococcales 28221|Deltaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS HSJS1_k127_2978195_1 1150469.RSPPHO_01859 1.141e-81 274.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,2JPYB@204441|Rhodospirillales 204441|Rhodospirillales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C HSJS1_k127_2988859_0 1434325.AZQN01000003_gene1943 3.395e-142 472.0 COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,47MXN@768503|Cytophagia 976|Bacteroidetes C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB HSJS1_k127_2988859_3 237368.SCABRO_00861 5.607e-30 135.0 COG3288@1|root,COG3288@2|Bacteria,2J0SW@203682|Planctomycetes 203682|Planctomycetes C COG3288 NAD NADP transhydrogenase alpha subunit - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM HSJS1_k127_2988859_1 203124.Tery_4705 2.631e-120 398.0 COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales 1117|Cyanobacteria C NAD NADP transhydrogenase alpha subunit pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM HSJS1_k127_2988859_2 765420.OSCT_2920 1.009e-78 270.0 COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi 200795|Chloroflexi P PFAM Integral membrane protein TerC - - - ko:K05794 - - - - ko00000 - - - TerC HSJS1_k127_2992905_3 861299.J421_6363 0.0003927 49.0 28W2Y@1|root,2ZI3W@2|Bacteria,1ZV8C@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - HSJS1_k127_2992905_2 1379270.AUXF01000002_gene1795 9.694e-06 57.0 2F5SD@1|root,33YB8@2|Bacteria,1ZUXW@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - HSJS1_k127_2992905_0 1379270.AUXF01000002_gene1794 7.028e-27 124.0 2F0M3@1|root,33TPR@2|Bacteria,1ZUAZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - HSJS1_k127_2992905_1 379066.GAU_2518 1.268e-24 106.0 COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes 142182|Gemmatimonadetes NU Type IV pilus assembly protein PilM; - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 HSJS1_k127_2996650_0 861299.J421_2707 4.573e-50 191.0 COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes 142182|Gemmatimonadetes I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding HSJS1_k127_299738_0 945713.IALB_2247 8.886e-39 161.0 COG2208@1|root,COG2208@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - SpoIIE HSJS1_k127_299738_1 1232683.ADIMK_3763 4.566e-24 118.0 COG1361@1|root,COG1361@2|Bacteria,1R2T2@1224|Proteobacteria,1T5WX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Conserved repeat domain - - - - - - - - - - - - - HSJS1_k127_2997568_3 518766.Rmar_0912 5.462e-14 73.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1FJ1J@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N HSJS1_k127_2997568_1 1519464.HY22_14185 9.942e-55 218.0 COG1266@1|root,COG2208@1|root,COG1266@2|Bacteria,COG2208@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity rsbU - 3.1.3.3 ko:K07052,ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Abi,GAF_2,GAF_3,SpoIIE HSJS1_k127_2997568_0 392500.Swoo_2854 1.295e-151 505.0 COG0457@1|root,COG0457@2|Bacteria,1PBYW@1224|Proteobacteria,1SWS0@1236|Gammaproteobacteria,2QDGR@267890|Shewanellaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 HSJS1_k127_2997568_2 477641.MODMU_1510 1.055e-40 162.0 COG2267@1|root,COG2267@2|Bacteria,2ID01@201174|Actinobacteria 201174|Actinobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 HSJS1_k127_2998965_1 1080067.BAZH01000029_gene1425 7.14e-39 171.0 COG2373@1|root,COG3420@1|root,COG2373@2|Bacteria,COG3420@2|Bacteria,1QV7E@1224|Proteobacteria,1SM3U@1236|Gammaproteobacteria,3WZU8@544|Citrobacter 1236|Gammaproteobacteria P Bacterial Ig-like domain (group 3) - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2 HSJS1_k127_2998965_0 715451.ambt_03875 2.773e-112 414.0 COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1R1M5@1224|Proteobacteria,1RQBW@1236|Gammaproteobacteria,465Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria A Protein conserved in bacteria - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - - HSJS1_k127_3007639_3 944481.JAFP01000001_gene1178 6.226e-38 144.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2M6RA@213113|Desulfurellales 28221|Deltaproteobacteria IQ COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 HSJS1_k127_3007639_5 1123400.KB904791_gene61 3.709e-25 111.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria 1224|Proteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding HSJS1_k127_3007639_0 234267.Acid_1167 2.33e-175 561.0 COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria 57723|Acidobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt HSJS1_k127_3007639_1 373994.Riv7116_2716 2.481e-104 366.0 COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1HKTB@1161|Nostocales 1117|Cyanobacteria U Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family - - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N HSJS1_k127_3007639_2 1192034.CAP_3243 2.353e-46 192.0 COG4219@1|root,COG4219@2|Bacteria,1PEGJ@1224|Proteobacteria,438JW@68525|delta/epsilon subdivisions,2X3UI@28221|Deltaproteobacteria,2YX4Y@29|Myxococcales 28221|Deltaproteobacteria DKT BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M56 HSJS1_k127_3007639_4 1192034.CAP_3244 4.912e-37 144.0 COG3682@1|root,COG3682@2|Bacteria,1RKDI@1224|Proteobacteria,4383A@68525|delta/epsilon subdivisions,2X3DA@28221|Deltaproteobacteria,2YVI8@29|Myxococcales 28221|Deltaproteobacteria K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R HSJS1_k127_3008329_1 869210.Marky_0170 2.169e-51 190.0 COG0530@1|root,COG0530@2|Bacteria,1WJ9P@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex HSJS1_k127_3008329_2 318167.Sfri_0463 4.773e-13 81.0 COG0526@1|root,COG0526@2|Bacteria,1NAHI@1224|Proteobacteria,1SCND@1236|Gammaproteobacteria,2QB1H@267890|Shewanellaceae 1236|Gammaproteobacteria CO Thioredoxin - - - - - - - - - - - - Thioredoxin,Thioredoxin_9 HSJS1_k127_3008329_3 1123058.KB894273_gene2202 1.609e-05 58.0 COG1368@1|root,COG1368@2|Bacteria,4PKS4@976|Bacteroidetes,1IMND@117743|Flavobacteriia 976|Bacteroidetes M Doxx family - - - - - - - - - - - - DoxX HSJS1_k127_3008329_0 1382306.JNIM01000001_gene1024 3.294e-86 296.0 COG1319@1|root,COG1319@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrB - 1.3.7.9 ko:K04109 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - CO_deh_flav_C,FAD_binding_5 HSJS1_k127_3010331_3 42256.RradSPS_1270 1.06e-23 113.0 COG2881@1|root,COG2881@2|Bacteria 2|Bacteria M overlaps another CDS with the same product name - - - - - - - - - - - - Yip1 HSJS1_k127_3010331_7 886293.Sinac_3528 1.253e-10 68.0 COG0759@1|root,COG0759@2|Bacteria,2J0M3@203682|Planctomycetes 203682|Planctomycetes S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic HSJS1_k127_3010331_6 575540.Isop_1483 2.143e-18 89.0 COG3536@1|root,COG3536@2|Bacteria,2J0WS@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 HSJS1_k127_3010331_0 1397528.Q671_00415 7.644e-62 222.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1XK9Y@135619|Oceanospirillales 135619|Oceanospirillales M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03767 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase HSJS1_k127_3010331_2 404589.Anae109_2532 3.172e-24 102.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales 28221|Deltaproteobacteria K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD HSJS1_k127_3010331_4 330214.NIDE1746 2.447e-22 108.0 COG4372@1|root,COG5343@1|root,COG4372@2|Bacteria,COG5343@2|Bacteria 2|Bacteria S Anti-sigma-K factor rskA - - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - LZ_Tnp_IS66,RskA,zf-HC2 HSJS1_k127_3010331_1 861299.J421_6273 9.552e-40 162.0 COG1595@1|root,COG1595@2|Bacteria,1ZU2B@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 HSJS1_k127_3010331_5 686340.Metal_0153 9.686e-19 93.0 COG5266@1|root,COG5266@2|Bacteria,1PNBH@1224|Proteobacteria,1SHZ7@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Domain of unknown function (DUF4198) - - - - - - - - - - - - DUF4198 HSJS1_k127_3020824_1 102125.Xen7305DRAFT_00026250 5.315e-45 168.0 COG0398@1|root,COG0398@2|Bacteria,1G3PG@1117|Cyanobacteria,3VIMD@52604|Pleurocapsales 1117|Cyanobacteria S PFAM SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc HSJS1_k127_3020824_0 398767.Glov_1982 6.265e-192 613.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WJAJ@28221|Deltaproteobacteria,43TZD@69541|Desulfuromonadales 28221|Deltaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family lpdA-4 - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc HSJS1_k127_3020824_2 671143.DAMO_1860 9.575e-41 153.0 COG1487@1|root,COG1487@2|Bacteria 2|Bacteria S nuclease activity - - - - - - - - - - - - PIN HSJS1_k127_3020824_3 671143.DAMO_1859 2.463e-20 92.0 COG5450@1|root,COG5450@2|Bacteria 2|Bacteria K positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - - - - - - - - - - VapB_antitoxin HSJS1_k127_3028988_3 1267535.KB906767_gene3857 1.229e-81 302.0 COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - - - - - - - - - - - AhpC-TSA,TPR_11,TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS HSJS1_k127_3028988_1 1122921.KB898188_gene270 1.356e-104 378.0 COG4658@1|root,COG4658@2|Bacteria,1U1P8@1239|Firmicutes,4IB5R@91061|Bacilli,273RA@186822|Paenibacillaceae 91061|Bacilli C electron transport chain - - - - - - - - - - - - - HSJS1_k127_3028988_2 1267535.KB906767_gene3867 7.722e-86 314.0 COG4658@1|root,COG4658@2|Bacteria 2|Bacteria C electron transport chain - - 1.6.5.8 ko:K00347,ko:K03614 - - - - ko00000,ko01000 - - - Complex1_51K,NQR2_RnfD_RnfE,RnfC_N HSJS1_k127_3028988_0 234267.Acid_3483 9.727e-117 400.0 COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria 57723|Acidobacteria S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS HSJS1_k127_3046558_0 903818.KI912268_gene2181 9.586e-56 222.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_3049514_0 240015.ACP_3334 3.23e-28 117.0 COG0776@1|root,COG0776@2|Bacteria,3Y55Y@57723|Acidobacteria,2JJPF@204432|Acidobacteriia 204432|Acidobacteriia L Belongs to the bacterial histone-like protein family - - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding HSJS1_k127_3049514_1 748658.KB907312_gene1512 5.321e-12 79.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB mshE - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N HSJS1_k127_3053005_1 237609.PSAKL28_33760 3.12e-118 391.0 COG1999@1|root,COG2010@1|root,COG1999@2|Bacteria,COG2010@2|Bacteria,1R725@1224|Proteobacteria,1S1UW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - Cytochrom_C,SCO1-SenC HSJS1_k127_3053005_0 1521187.JPIM01000010_gene2151 5.545e-201 640.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,37693@32061|Chloroflexia 32061|Chloroflexia F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH HSJS1_k127_3053005_2 589865.DaAHT2_1662 3.811e-82 283.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MIJD@213118|Desulfobacterales 28221|Deltaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW HSJS1_k127_3060296_8 1382303.JPOM01000001_gene345 4.31e-26 116.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,2KGHU@204458|Caulobacterales 204458|Caulobacterales J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p HSJS1_k127_3060296_6 945713.IALB_0263 5.818e-40 166.0 COG5000@1|root,COG5000@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K07710,ko:K10942 ko02020,ko05111,map02020,map05111 M00500,M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS HSJS1_k127_3060296_7 1499967.BAYZ01000171_gene5600 1.612e-36 144.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 HSJS1_k127_3060296_3 1120973.AQXL01000083_gene2911 9.469e-82 293.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,279UI@186823|Alicyclobacillaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle appA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 HSJS1_k127_3060296_2 517418.Ctha_1639 6.416e-89 303.0 COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi 1090|Chlorobi P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 HSJS1_k127_3060296_4 1519464.HY22_01690 1.462e-70 251.0 COG1173@1|root,COG1173@2|Bacteria,1FD9T@1090|Chlorobi 1090|Chlorobi EP PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N HSJS1_k127_3060296_1 404589.Anae109_1319 5.755e-105 354.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,2YUD8@29|Myxococcales 28221|Deltaproteobacteria F Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth HSJS1_k127_3060296_5 1449355.JQNR01000004_gene1287 5.025e-40 166.0 COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria 201174|Actinobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H HSJS1_k127_3060296_0 671143.DAMO_0704 1.792e-123 408.0 COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C HSJS1_k127_3061051_6 316274.Haur_3579 7.136e-31 138.0 COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia 32061|Chloroflexia M PFAM O-antigen polymerase - - - - - - - - - - - - Wzy_C HSJS1_k127_3061051_9 273068.TTE0733 9.384e-08 66.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,42HYM@68295|Thermoanaerobacterales 186801|Clostridia M PFAM lipopolysaccharide biosynthesis - - - - - - - - - - - - GNVR,Wzz HSJS1_k127_3061051_2 1304872.JAGC01000009_gene604 3.86e-58 209.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2M9N9@213115|Desulfovibrionales 28221|Deltaproteobacteria M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase epsL - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 HSJS1_k127_3061051_1 1245475.ANAE01000194_gene3087 2.911e-80 280.0 COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4EGJ1@85012|Streptosporangiales 201174|Actinobacteria C Zinc-binding dehydrogenase qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 HSJS1_k127_3061051_8 221288.JH992901_gene3283 3.144e-23 102.0 COG1669@1|root,COG1669@2|Bacteria,1G7R5@1117|Cyanobacteria,1JMB5@1189|Stigonemataceae 1117|Cyanobacteria S Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 HSJS1_k127_3061051_5 163908.KB235896_gene4768 5.081e-37 143.0 COG2361@1|root,COG2361@2|Bacteria,1G7E2@1117|Cyanobacteria,1HU2G@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 HSJS1_k127_3061051_0 1121406.JAEX01000003_gene1503 4.844e-206 669.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WJ0I@28221|Deltaproteobacteria,2MG34@213115|Desulfovibrionales 28221|Deltaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI HSJS1_k127_3061051_3 1385935.N836_11195 2.745e-49 180.0 COG1569@1|root,COG1569@2|Bacteria,1G7HY@1117|Cyanobacteria,1HD1I@1150|Oscillatoriales 1117|Cyanobacteria S PIN domain - - - - - - - - - - - - PIN_3 HSJS1_k127_3061051_7 1089550.ATTH01000001_gene651 4.253e-26 109.0 COG4226@1|root,COG4226@2|Bacteria 2|Bacteria K protein encoded in hypervariable junctions of pilus gene clusters - - - - - - - - - - - - HicB HSJS1_k127_3061051_4 243231.GSU0812 2.555e-47 195.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43TNJ@69541|Desulfuromonadales 28221|Deltaproteobacteria T histidine kinase, HAMP ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 HSJS1_k127_3066010_3 1484479.DI14_04000 1.064e-63 225.0 COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,3WFE6@539002|Bacillales incertae sedis 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N HSJS1_k127_3066010_5 383372.Rcas_0137 1.539e-29 130.0 COG1216@1|root,COG1216@2|Bacteria,2GAH6@200795|Chloroflexi,377WE@32061|Chloroflexia 32061|Chloroflexia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 HSJS1_k127_3066010_6 1218084.BBJK01000058_gene4476 3.302e-15 89.0 COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2VQSW@28216|Betaproteobacteria,1K1NY@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM polysaccharide biosynthesis protein - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C HSJS1_k127_3066010_8 1197906.CAJQ02000003_gene3219 6.253e-09 60.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Resolvase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom HSJS1_k127_3066010_7 1123368.AUIS01000032_gene1402 1.969e-10 69.0 COG0425@1|root,COG0425@2|Bacteria 2|Bacteria O sulfur carrier activity - - - - - - - - - - - - DrsE,TusA HSJS1_k127_3066010_9 309799.DICTH_0778 1.752e-08 66.0 COG0389@1|root,COG0389@2|Bacteria 2|Bacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - Cdd1,IMS,IMS_C,IMS_HHH HSJS1_k127_3066010_0 671143.DAMO_1629 1.459e-163 531.0 COG0138@1|root,COG0138@2|Bacteria,2NNQ2@2323|unclassified Bacteria 2|Bacteria F Bifunctional purine biosynthesis protein PurH purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS HSJS1_k127_3066010_11 330214.NIDE0540 2.163e-06 59.0 COG2834@1|root,COG2834@2|Bacteria,3J1C6@40117|Nitrospirae 40117|Nitrospirae M Outer membrane lipoprotein carrier protein LolA - - - ko:K03634 - - - - ko00000 - - - LolA HSJS1_k127_3066010_2 443143.GM18_0685 2.157e-65 244.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,43SCB@69541|Desulfuromonadales 28221|Deltaproteobacteria H Belongs to the FPP GGPP synthase family ispB - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt HSJS1_k127_3066010_10 525904.Tter_2039 1.465e-07 65.0 COG3408@1|root,COG3408@2|Bacteria 2|Bacteria G Glycogen debranching enzyme - - - - - - - - - - - - Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N HSJS1_k127_3066010_4 1120985.AUMI01000014_gene775 1.735e-59 230.0 COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,4H20C@909932|Negativicutes 909932|Negativicutes M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 HSJS1_k127_3066010_1 448385.sce7239 4.497e-84 284.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2YTT7@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1276 CTP_synth_N,GATase HSJS1_k127_3066472_0 1121413.JMKT01000009_gene1936 1.296e-87 298.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2WJR5@28221|Deltaproteobacteria,2MAEE@213115|Desulfovibrionales 28221|Deltaproteobacteria M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - LysM,MS_channel,TM_helix HSJS1_k127_3066472_1 1267533.KB906740_gene287 3.059e-06 53.0 COG0457@1|root,COG0823@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - DUF4214,SBBP,TPR_19 HSJS1_k127_3070345_4 679197.HMPREF9336_01645 4.695e-13 74.0 COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria 201174|Actinobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP HSJS1_k127_3070345_2 1121405.dsmv_0956 2.273e-92 316.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MKU8@213118|Desulfobacterales 28221|Deltaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family - - 1.4.1.1,4.3.1.12 ko:K01750,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 - R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall HSJS1_k127_3070345_1 234267.Acid_1737 9.729e-153 522.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_3070345_3 1183438.GKIL_3396 1.318e-48 180.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_ECF HSJS1_k127_3070345_0 1089550.ATTH01000001_gene1831 2.075e-165 554.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_3070345_5 326427.Cagg_1949 5.261e-08 62.0 COG1247@1|root,COG1247@2|Bacteria,2G9YI@200795|Chloroflexi,377A3@32061|Chloroflexia 32061|Chloroflexia M PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 HSJS1_k127_3070345_6 269799.Gmet_2032 8.417e-07 56.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42P80@68525|delta/epsilon subdivisions,2WMCB@28221|Deltaproteobacteria,43TGI@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 HSJS1_k127_3070578_2 266779.Meso_2457 0.0004832 49.0 COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,1QY5D@1224|Proteobacteria,2TXGC@28211|Alphaproteobacteria,43N3X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE HSJS1_k127_3070578_0 477641.MODMU_2527 4.514e-06 51.0 COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria 201174|Actinobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 HSJS1_k127_3074562_2 745718.JADT01000014_gene128 9.111e-14 71.0 2ETTP@1|root,33MB1@2|Bacteria,4NZFX@976|Bacteroidetes,1I6T5@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - HSJS1_k127_3074562_0 1047013.AQSP01000114_gene700 2.919e-40 151.0 COG3093@1|root,COG3093@2|Bacteria,2NR60@2323|unclassified Bacteria 2|Bacteria K Helix-turn-helix XRE-family like proteins higA - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3,HTH_31 HSJS1_k127_3074562_1 1112212.JH584235_gene3321 1.371e-33 132.0 COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,2K6PM@204457|Sphingomonadales 204457|Sphingomonadales S RelE-like toxin of type II toxin-antitoxin system HigB - - - - - - - - - - - - HigB-like_toxin HSJS1_k127_3094647_2 1166018.FAES_3476 2.125e-14 85.0 COG0526@1|root,COG1729@1|root,COG0526@2|Bacteria,COG1729@2|Bacteria,4NKFI@976|Bacteroidetes,47MM5@768503|Cytophagia 976|Bacteroidetes CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,DUF4369 HSJS1_k127_3094647_1 1382359.JIAL01000001_gene2531 1.547e-19 101.0 COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia 204432|Acidobacteriia S TIGRFAM VWFA-related Acidobacterial domain - - - - - - - - - - - - - HSJS1_k127_3094647_0 215803.DB30_8355 6.815e-107 369.0 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales 28221|Deltaproteobacteria L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,NUDIX HSJS1_k127_3099651_0 429009.Adeg_0304 3.826e-82 284.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales 186801|Clostridia F Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C HSJS1_k127_3099651_1 1297742.A176_05717 1.473e-30 124.0 COG0308@1|root,COG0308@2|Bacteria 2|Bacteria E peptide catabolic process - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 HSJS1_k127_3100279_0 1133850.SHJG_0483 0.0008916 51.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator, SARP family - - - - - - - - - - - - BTAD,HTH_3,HTH_31,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C HSJS1_k127_3100323_2 515635.Dtur_0062 1.456e-13 75.0 COG0842@1|root,COG0842@2|Bacteria 2|Bacteria V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane HSJS1_k127_3100323_1 713587.THITH_07380 4.805e-31 142.0 COG0457@1|root,COG0457@2|Bacteria 713587.THITH_07380|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_3100323_0 335543.Sfum_1617 7.304e-195 626.0 COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_3111431_1 221288.JH992901_gene1727 5.165e-61 218.0 COG1215@1|root,COG1215@2|Bacteria,1GHF8@1117|Cyanobacteria 1117|Cyanobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_3111431_3 1254432.SCE1572_51135 1.116e-10 72.0 COG0500@1|root,COG1853@1|root,COG1853@2|Bacteria,COG2226@2|Bacteria,1RGYM@1224|Proteobacteria,4346C@68525|delta/epsilon subdivisions,2X20P@28221|Deltaproteobacteria,2Z2GY@29|Myxococcales 28221|Deltaproteobacteria Q Flavin reductase like domain - - 1.5.1.36 ko:K00484,ko:K16048 ko00350,ko00740,ko00984,ko01100,ko01120,ko01220,map00350,map00740,map00984,map01100,map01120,map01220 - R02698,R03299,R05705,R09748,R09750,R09819 RC00046,RC00126,RC00236 ko00000,ko00001,ko01000 - - - Flavin_Reduct,Methyltransf_11 HSJS1_k127_3111431_0 1131269.AQVV01000013_gene1767 6.657e-87 302.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,Radical_SAM HSJS1_k127_3111431_2 251221.35211385 7.474e-12 76.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 HSJS1_k127_3117326_1 1144275.COCOR_04646 1.801e-30 123.0 COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria,2YXVU@29|Myxococcales 28221|Deltaproteobacteria P Membrane protein, TerC - - - ko:K05794 - - - - ko00000 - - - TerC HSJS1_k127_3117326_0 1469607.KK073768_gene2485 6.13e-42 166.0 COG1682@1|root,COG1682@2|Bacteria,1G0IN@1117|Cyanobacteria,1HKMP@1161|Nostocales 1117|Cyanobacteria GM Transport permease protein - - - ko:K09690 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC2_membrane HSJS1_k127_3117326_2 323261.Noc_0727 1.01e-23 117.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1SIJC@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS HSJS1_k127_3121906_0 502025.Hoch_5838 3.576e-100 354.0 COG0845@1|root,COG0845@2|Bacteria,1Q2C6@1224|Proteobacteria,437YK@68525|delta/epsilon subdivisions,2X38G@28221|Deltaproteobacteria,2YUTX@29|Myxococcales 28221|Deltaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K03585,ko:K18306 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3 HSJS1_k127_3121906_1 502025.Hoch_5839 7.895e-32 130.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJEY@28221|Deltaproteobacteria,2YUDX@29|Myxococcales 28221|Deltaproteobacteria V ABC transporter - - - - - - - - - - - - ABC_membrane,ABC_tran,Peptidase_C39 HSJS1_k127_3122005_1 197221.22293772 6.667e-48 187.0 COG0612@1|root,COG0612@2|Bacteria,1G3GH@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Peptidase M16 inactive domain - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_3122005_2 309801.trd_A0561 5.045e-33 144.0 COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia 189775|Thermomicrobia S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_3122005_3 500153.JOEK01000001_gene3866 3.74e-32 136.0 COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria 201174|Actinobacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 HSJS1_k127_3122005_4 713586.KB900536_gene432 8.554e-30 128.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1WW81@135613|Chromatiales 135613|Chromatiales E TIGRFAM Serine O-acetyltransferase - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N HSJS1_k127_3122005_0 1125863.JAFN01000001_gene1992 7.429e-91 308.0 COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria 28221|Deltaproteobacteria N Putative transposase, YhgA-like - - - - - - - - - - - - DUF4351,Transposase_31 HSJS1_k127_3122547_0 404589.Anae109_1755 1.128e-21 101.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 HSJS1_k127_3129239_15 641491.DND132_0275 8.21e-10 62.0 COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales 28221|Deltaproteobacteria F PFAM Adenylate cyclase - - 4.6.1.1 ko:K05873 ko00230,map00230 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - CYTH HSJS1_k127_3129239_7 251221.35211032 4.233e-36 151.0 COG1208@1|root,COG1208@2|Bacteria 2|Bacteria JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon cugP GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363 2.7.7.13,5.4.2.8 ko:K00966,ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00361,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase HSJS1_k127_3129239_0 713587.THITH_02010 7.067e-130 425.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales 135613|Chromatiales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase HSJS1_k127_3129239_2 1089550.ATTH01000001_gene1576 1.086e-71 246.0 COG0652@1|root,COG0652@2|Bacteria,4PM5K@976|Bacteroidetes,1FJNB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - HEAT,HEAT_2,Pro_isomerase HSJS1_k127_3129239_14 1246484.D479_09522 1.505e-11 67.0 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,3NFKT@45667|Halobacillus 91061|Bacilli J Ribosomal protein L34 rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 HSJS1_k127_3129239_12 243159.AFE_0034 6.424e-14 77.0 COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,1T8KZ@1236|Gammaproteobacteria,2ND3B@225057|Acidithiobacillales 225057|Acidithiobacillales J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P HSJS1_k127_3129239_9 338963.Pcar_3144 1.329e-16 87.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,42VNC@68525|delta/epsilon subdivisions,2WRIM@28221|Deltaproteobacteria,43VTA@69541|Desulfuromonadales 28221|Deltaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic HSJS1_k127_3129239_3 1267535.KB906767_gene3477 1.363e-63 241.0 COG0706@1|root,COG0706@2|Bacteria,3Y3TD@57723|Acidobacteria,2JI2B@204432|Acidobacteriia 204432|Acidobacteriia U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas HSJS1_k127_3129239_13 1121441.AUCX01000007_gene1122 1.427e-13 82.0 COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria,2M9KW@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Single-stranded nucleic acid binding R3H - - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H HSJS1_k127_3129239_11 856793.MICA_28 2.028e-15 87.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,4BQP6@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB HSJS1_k127_3129239_1 1125863.JAFN01000001_gene2683 3.927e-86 292.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria 28221|Deltaproteobacteria D PFAM Cobyrinic acid ac-diamide synthase soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 HSJS1_k127_3129239_4 443143.GM18_4421 4.818e-63 229.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,43U5F@69541|Desulfuromonadales 28221|Deltaproteobacteria K PFAM ParB domain protein nuclease parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc HSJS1_k127_3129239_10 796942.HMPREF9623_01423 3.668e-16 90.0 COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia 186801|Clostridia M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin HSJS1_k127_3129239_8 335543.Sfum_0219 8.647e-17 95.0 COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales 28221|Deltaproteobacteria O Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest HSJS1_k127_3129239_6 485915.Dret_2249 4.319e-48 193.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M9N8@213115|Desulfovibrionales 28221|Deltaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 HSJS1_k127_3129239_5 573370.DMR_39450 3.676e-48 181.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M9N8@213115|Desulfovibrionales 28221|Deltaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 HSJS1_k127_3134543_0 1211815.CBYP010000042_gene2382 3.44e-48 181.0 COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4EURQ@85013|Frankiales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 HSJS1_k127_3134543_2 383372.Rcas_1007 3.284e-23 101.0 COG1724@1|root,COG1724@2|Bacteria 2|Bacteria N mRNA binding - - - - - - - - - - - - HicA_toxin HSJS1_k127_3134543_1 118161.KB235922_gene3231 6.086e-24 103.0 COG1598@1|root,COG1598@2|Bacteria,1G89J@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - - HSJS1_k127_3134543_3 1211115.ALIQ01000037_gene3998 3.531e-09 67.0 29IJ4@1|root,305GB@2|Bacteria,1RI8V@1224|Proteobacteria,2U9UM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1579) - - - - - - - - - - - - DUF1579 HSJS1_k127_3134543_4 1229203.KI301992_gene2346 5.725e-05 48.0 COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria,3UWY6@52018|unclassified Actinobacteria (class) 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 HSJS1_k127_313575_1 56780.SYN_01407 7.078e-52 195.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria,2MQKM@213462|Syntrophobacterales 28221|Deltaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly HSJS1_k127_313575_0 1192034.CAP_4130 8.879e-83 287.0 COG0308@1|root,COG0308@2|Bacteria 2|Bacteria E peptide catabolic process - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 HSJS1_k127_3136261_1 1121920.AUAU01000025_gene2325 1.351e-28 127.0 COG0457@1|root,COG0457@2|Bacteria,3Y89N@57723|Acidobacteria 57723|Acidobacteria G Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 HSJS1_k127_3136261_0 1303518.CCALI_00772 2.001e-132 430.0 COG0473@1|root,COG0473@2|Bacteria 2|Bacteria CE 3-isopropylmalate dehydrogenase activity icd - 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh HSJS1_k127_3138916_2 1382359.JIAL01000001_gene986 2.249e-52 197.0 COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia 204432|Acidobacteriia U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG HSJS1_k127_3138916_0 1047013.AQSP01000034_gene1652 1.976e-134 445.0 COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG HSJS1_k127_3138916_3 706587.Desti_4871 3.338e-19 94.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MQKT@213462|Syntrophobacterales 28221|Deltaproteobacteria U TIGRFAM preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC HSJS1_k127_3138916_1 1122218.KB893653_gene459 3.517e-119 398.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,1JQTM@119045|Methylobacteriaceae 28211|Alphaproteobacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT HSJS1_k127_3138916_4 404589.Anae109_0184 7.841e-09 66.0 COG2834@1|root,COG2834@2|Bacteria 2|Bacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lola3 - - ko:K03634 - - - - ko00000 - - - LolA HSJS1_k127_3147403_3 391625.PPSIR1_10520 7.846e-11 64.0 COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales 28221|Deltaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - Radical_SAM,adh_short HSJS1_k127_3147403_0 1121033.AUCF01000016_gene5495 4.149e-104 359.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria,2JQ2G@204441|Rhodospirillales 204441|Rhodospirillales C FAD binding domain - - 1.1.3.8 ko:K00103 ko00053,ko01100,map00053,map01100 M00129 R00647,R03184,R10053 RC00195,RC00346,RC00869 ko00000,ko00001,ko00002,ko01000 - - - ALO,FAD_binding_4 HSJS1_k127_3147403_2 903818.KI912268_gene1614 3.92e-61 221.0 COG1427@1|root,COG1427@2|Bacteria,3Y3PU@57723|Acidobacteria 57723|Acidobacteria S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth HSJS1_k127_3147403_1 1267535.KB906767_gene3177 1.4e-77 261.0 COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia 204432|Acidobacteriia K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind HSJS1_k127_3148376_0 1121920.AUAU01000024_gene2388 9.956e-78 283.0 COG3005@1|root,COG3043@1|root,COG3005@2|Bacteria,COG3043@2|Bacteria,3Y4BJ@57723|Acidobacteria 57723|Acidobacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 HSJS1_k127_3148376_1 880073.Calab_1129 9.092e-73 252.0 COG0327@1|root,COG0327@2|Bacteria,2NR2X@2323|unclassified Bacteria 2|Bacteria S NIF3 (NGG1p interacting factor 3) ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - NIF3 HSJS1_k127_3152281_1 1121382.JQKG01000002_gene4328 3.067e-33 138.0 COG1132@1|root,COG1132@2|Bacteria,1WJR1@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HSJS1_k127_3152281_0 1267535.KB906767_gene751 4.057e-138 472.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_3152281_2 926560.KE387027_gene263 1.284e-20 95.0 COG2120@1|root,COG2120@2|Bacteria 2|Bacteria S N-acetylglucosaminylinositol deacetylase activity - - - ko:K22135 - - - - ko00000,ko01000 - - - PIG-L HSJS1_k127_3164759_1 1163407.UU7_09065 1.596e-80 276.0 COG1231@1|root,COG1231@2|Bacteria,1RA9M@1224|Proteobacteria,1S3DF@1236|Gammaproteobacteria,1XCPQ@135614|Xanthomonadales 135614|Xanthomonadales E Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase HSJS1_k127_3164759_0 518766.Rmar_1439 3.579e-222 711.0 COG0457@1|root,COG0457@2|Bacteria 518766.Rmar_1439|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_3164759_2 518766.Rmar_1438 6.225e-66 235.0 COG0457@1|root,COG0457@2|Bacteria 518766.Rmar_1438|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_3174040_3 1283299.AUKG01000002_gene4619 2.738e-37 150.0 COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria 84995|Rubrobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M HSJS1_k127_3174040_1 1242864.D187_006399 2.013e-82 291.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales 28221|Deltaproteobacteria D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE HSJS1_k127_3174040_2 1123354.AUDR01000017_gene42 6.212e-58 216.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,1KRF5@119069|Hydrogenophilales 119069|Hydrogenophilales M Glycosyltransferase family 28 N-terminal domain - - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 HSJS1_k127_3174040_0 1379698.RBG1_1C00001G0397 7.673e-147 494.0 COG0773@1|root,COG0773@2|Bacteria,2NNPU@2323|unclassified Bacteria 2|Bacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093,iJN678.murC Mur_ligase,Mur_ligase_C,Mur_ligase_M HSJS1_k127_3175582_0 502025.Hoch_5038 3.081e-318 1005.0 COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales 28221|Deltaproteobacteria O Peptidase family M28 - - - - - - - - - - - - PA,PD40,PDZ_2,Peptidase_M28 HSJS1_k127_3175582_1 1267535.KB906767_gene4448 2.828e-34 143.0 COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia 204432|Acidobacteriia S PFAM von Willebrand factor type A - - - - - - - - - - - - VWA,VWA_2,VWA_3 HSJS1_k127_3178863_1 378806.STAUR_0571 1.876e-34 134.0 COG2304@1|root,COG2304@2|Bacteria,1R8EZ@1224|Proteobacteria,433AE@68525|delta/epsilon subdivisions,2WYFQ@28221|Deltaproteobacteria,2YY3M@29|Myxococcales 28221|Deltaproteobacteria S IgA Peptidase M64 - - - - - - - - - - - - M64_N,Peptidase_M64 HSJS1_k127_3178863_0 1267534.KB906755_gene3968 2.772e-111 383.0 COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia 204432|Acidobacteriia T Sigma factor PP2C-like phosphatases - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_2,SpoIIE HSJS1_k127_3180109_1 1318628.MARLIPOL_06959 9.94e-61 236.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,4658X@72275|Alteromonadaceae 1236|Gammaproteobacteria S exporters of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - LolA_like,MMPL,Polyketide_cyc2 HSJS1_k127_3180109_4 1089550.ATTH01000001_gene1118 8.777e-30 123.0 COG5394@1|root,COG5394@2|Bacteria,4PF5Z@976|Bacteroidetes,1FK70@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S PHB/PHA accumulation regulator DNA-binding domain - - - - - - - - - - - - PHB_acc_N HSJS1_k127_3180109_5 981327.F925_01981 6.547e-16 83.0 COG3937@1|root,COG3937@2|Bacteria,1N7X8@1224|Proteobacteria,1SBMI@1236|Gammaproteobacteria,3NNGS@468|Moraxellaceae 1236|Gammaproteobacteria S Poly(hydroxyalcanoate) granule associated protein (phasin) phaI - - - - - - - - - - - Phasin HSJS1_k127_3180109_3 1089550.ATTH01000001_gene1248 8.337e-33 139.0 COG3937@1|root,COG4876@1|root,COG3937@2|Bacteria,COG4876@2|Bacteria,4PF2X@976|Bacteroidetes,1FK26@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2188) - - - - - - - - - - - - DUF2188,Phasin HSJS1_k127_3180109_0 626887.J057_14370 4.034e-122 406.0 COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,1RRTH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin HSJS1_k127_3180109_2 215803.DB30_8469 6.803e-46 186.0 COG1729@1|root,COG1729@2|Bacteria,1N780@1224|Proteobacteria,42V4V@68525|delta/epsilon subdivisions,2WR6U@28221|Deltaproteobacteria,2YW0N@29|Myxococcales 28221|Deltaproteobacteria S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - - HSJS1_k127_3180236_5 443143.GM18_2265 2.679e-18 87.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales 28221|Deltaproteobacteria E Belongs to the TrpC family trpC - 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2494 IGPS HSJS1_k127_3180236_3 1042377.AFPJ01000037_gene2999 6.729e-34 142.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,466TM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI HSJS1_k127_3180236_0 497964.CfE428DRAFT_4159 5.163e-160 517.0 COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia 74201|Verrucomicrobia E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP HSJS1_k127_3180236_2 1121918.ARWE01000001_gene2327 1.242e-76 267.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TXE@69541|Desulfuromonadales 28221|Deltaproteobacteria E Tryptophan synthase alpha chain trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA HSJS1_k127_3180236_4 243231.GSU1828 1.594e-18 99.0 COG1605@1|root,COG1605@2|Bacteria,1Q1RX@1224|Proteobacteria,42U9H@68525|delta/epsilon subdivisions,2WQ7P@28221|Deltaproteobacteria,43SMW@69541|Desulfuromonadales 28221|Deltaproteobacteria E Chorismate mutase type II - - 5.4.99.5 ko:K04093 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 HSJS1_k127_3180236_1 234267.Acid_7885 1.82e-111 368.0 COG2876@1|root,COG2876@2|Bacteria,3Y2SV@57723|Acidobacteria 57723|Acidobacteria E NeuB family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 HSJS1_k127_3180247_5 452637.Oter_1804 7.278e-21 96.0 COG4314@1|root,COG4314@2|Bacteria,46WQY@74201|Verrucomicrobia,3K7YT@414999|Opitutae 414999|Opitutae C lipoprotein involved in nitrous oxide reduction - - - - - - - - - - - - - HSJS1_k127_3180247_0 756499.Desde_0188 4.197e-88 309.0 COG3420@1|root,COG3420@2|Bacteria,1U542@1239|Firmicutes,24Z13@186801|Clostridia,264G0@186807|Peptococcaceae 186801|Clostridia P TIGRFAM parallel beta-helix repeat (two copies) - - - ko:K07218 - - - - ko00000 - - - NosD HSJS1_k127_3180247_2 404589.Anae109_0247 3.396e-44 181.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,430KF@68525|delta/epsilon subdivisions,2WW09@28221|Deltaproteobacteria 28221|Deltaproteobacteria V ABC transporter - - - ko:K01990,ko:K19340 ko02010,map02010 M00254,M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 - - ABC_tran HSJS1_k127_3180247_6 929713.NIASO_09240 3.091e-19 96.0 COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia 976|Bacteroidetes C lipoprotein involved in nitrous oxide reduction - - - ko:K19342 - - - - ko00000 - - - NosL HSJS1_k127_3180247_3 404589.Anae109_0249 2.024e-41 164.0 COG1277@1|root,COG1277@2|Bacteria,1PK2D@1224|Proteobacteria,437V7@68525|delta/epsilon subdivisions,2WWIN@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ABC-2 family transporter protein - - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2 HSJS1_k127_3180247_1 880073.Calab_1817 1.601e-76 269.0 COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria 2|Bacteria U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 HSJS1_k127_3180247_4 880073.Calab_1818 1.194e-28 117.0 COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria 2|Bacteria P Belongs to the bacterial solute-binding protein 9 family znuA - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA HSJS1_k127_3188452_0 1123257.AUFV01000002_gene2400 1.11e-16 92.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1X54E@135614|Xanthomonadales 135614|Xanthomonadales M rhs family - - - - - - - - - - - - RHS_repeat HSJS1_k127_3193166_0 448385.sce0381 3.162e-28 124.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3205872_1 326427.Cagg_2826 1.162e-59 219.0 COG0438@1|root,COG0438@2|Bacteria,2G6YP@200795|Chloroflexi,374VD@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 HSJS1_k127_3205872_0 518766.Rmar_2716 7.526e-101 339.0 COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1FIY6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Glycosyltransferase like family 2 arnC - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_3205872_2 1047013.AQSP01000144_gene855 1.168e-48 179.0 COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria 2|Bacteria H Flavin containing amine oxidoreductase - - 1.3.3.15,1.3.3.4,5.4.99.9 ko:K00231,ko:K01854 ko00052,ko00520,ko00860,ko01100,ko01110,map00052,map00520,map00860,map01100,map01110 M00121 R00505,R03222,R04178,R09009 RC00317,RC00885,RC02396 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase,NAD_binding_8 HSJS1_k127_3222889_2 1173028.ANKO01000031_gene3928 3.99e-44 169.0 COG1216@1|root,COG3222@1|root,COG1216@2|Bacteria,COG3222@2|Bacteria,1G0X3@1117|Cyanobacteria,1HHXX@1150|Oscillatoriales 1117|Cyanobacteria S Glycosyl transferase family 2 - - - ko:K09931 - - - - ko00000 - - - DUF2064,Glycos_transf_2 HSJS1_k127_3222889_4 675816.VIA_002741 1.474e-16 84.0 2ER5N@1|root,33IR8@2|Bacteria,1NNIR@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3222889_0 234267.Acid_4267 1.255e-197 644.0 COG0577@1|root,COG0577@2|Bacteria,3Y3U3@57723|Acidobacteria 57723|Acidobacteria V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_3222889_1 1489678.RDMS_12985 2.856e-88 300.0 COG1230@1|root,COG1230@2|Bacteria 2|Bacteria P cation diffusion facilitator family transporter zitB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - iNRG857_1313.NRG857_03325,iPC815.YPO1129 Cation_efflux,ZT_dimer HSJS1_k127_3222889_3 1242864.D187_003858 2.425e-29 119.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787,ko:K15726 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 - - ACR_tran HSJS1_k127_322679_0 1379858.N508_00864 4.207e-157 533.0 COG0841@1|root,COG0841@2|Bacteria,2GESU@200930|Deferribacteres 200930|Deferribacteres V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran HSJS1_k127_322679_1 690850.Desaf_2000 5.18e-48 190.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WK41@28221|Deltaproteobacteria,2M9V3@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005,ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 HSJS1_k127_322679_2 883.DvMF_2159 8.017e-21 108.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MRU@68525|delta/epsilon subdivisions,2WIQX@28221|Deltaproteobacteria,2MA64@213115|Desulfovibrionales 28221|Deltaproteobacteria M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - - - - - - - - - - OEP HSJS1_k127_322679_3 1340434.AXVA01000008_gene3727 3.012e-15 85.0 COG1309@1|root,COG1309@2|Bacteria,1VFD2@1239|Firmicutes,4HM3Q@91061|Bacilli,1ZIA5@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N HSJS1_k127_3229431_0 232721.Ajs_0870 6.284e-12 78.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,4A9ZQ@80864|Comamonadaceae 28216|Betaproteobacteria H Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 HSJS1_k127_325147_1 477974.Daud_2045 1.231e-78 277.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,2609D@186807|Peptococcaceae 186801|Clostridia S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 HSJS1_k127_325147_2 574087.Acear_0620 1.061e-57 218.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales 186801|Clostridia S CBS domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 HSJS1_k127_325147_3 1382359.JIAL01000001_gene1045 5.569e-22 104.0 COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria,2JJPS@204432|Acidobacteriia 204432|Acidobacteriia J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 HSJS1_k127_325147_0 1121423.JONT01000001_gene1978 2.04e-84 289.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,2610I@186807|Peptococcaceae 186801|Clostridia S 7TM receptor with intracellular HD hydrolase - - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD HSJS1_k127_3252220_2 477641.MODMU_3192 2.428e-41 168.0 COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales 201174|Actinobacteria S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 HSJS1_k127_3252220_3 1173027.Mic7113_2260 2.221e-17 87.0 COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria,1H6X4@1150|Oscillatoriales 1117|Cyanobacteria O Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 HSJS1_k127_3252220_1 629773.AORY01000004_gene634 1.197e-44 188.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,2JZUV@204457|Sphingomonadales 204457|Sphingomonadales G beta-N-acetylhexosaminidase nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 HSJS1_k127_3252220_0 243231.GSU1822 2.275e-237 762.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales 28221|Deltaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V HSJS1_k127_3252220_4 1411123.JQNH01000001_gene1776 4.31e-14 72.0 COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2UEUU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K18828 - - - - ko00000,ko01000,ko02048,ko03016 - - - PIN HSJS1_k127_3254446_0 391625.PPSIR1_08217 5.334e-125 412.0 COG0057@1|root,COG0057@2|Bacteria,1N2N1@1224|Proteobacteria 1224|Proteobacteria G Glyceraldehyde-3-phosphate dehydrogenase - - 1.2.1.59 ko:K00150 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166 R01061,R01063 RC00149 ko00000,ko00001,ko00002,ko01000 - - - DapB_N,Gp_dh_C HSJS1_k127_3254446_2 391625.PPSIR1_35872 1.468e-33 143.0 COG1234@1|root,COG1234@2|Bacteria,1Q2BQ@1224|Proteobacteria,430AM@68525|delta/epsilon subdivisions,2WVV1@28221|Deltaproteobacteria,2YUSD@29|Myxococcales 28221|Deltaproteobacteria S Beta-lactamase superfamily domain - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 HSJS1_k127_3254446_1 234267.Acid_5841 1.079e-61 238.0 COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria 57723|Acidobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr HSJS1_k127_3259194_1 1121920.AUAU01000006_gene254 1.143e-37 144.0 COG2403@1|root,COG2403@2|Bacteria,3Y6GM@57723|Acidobacteria 57723|Acidobacteria S cyclic 2,3-diphosphoglycerate synthetase activity - - - - - - - - - - - - - HSJS1_k127_3259194_0 338963.Pcar_2837 1.33e-112 374.0 COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,42YN9@68525|delta/epsilon subdivisions,2WTT2@28221|Deltaproteobacteria 28221|Deltaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 HSJS1_k127_326356_0 631362.Thi970DRAFT_03295 9.904e-99 337.0 COG2801@1|root,COG2801@2|Bacteria,1R6TH@1224|Proteobacteria,1RRWS@1236|Gammaproteobacteria,1X2I8@135613|Chromatiales 135613|Chromatiales L Mu transposase, C-terminal - - - - - - - - - - - - HTH_32,Mu-transpos_C,rve HSJS1_k127_326356_1 1121937.AUHJ01000036_gene2810 2.771e-50 190.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,4658U@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3267 Type II secretory pathway, component ExeA - - - - - - - - - - - - AAA_22 HSJS1_k127_3264707_0 1177179.A11A3_06096 1.974e-71 254.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XHCU@135619|Oceanospirillales 135619|Oceanospirillales V MATE efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE HSJS1_k127_3266917_0 880073.Calab_2975 2.362e-190 621.0 COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,2NQF1@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolase family 65, C-terminal domain pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.216,2.4.1.64,2.4.1.8,3.1.3.12,3.2.1.28,5.4.2.6 ko:K00691,ko:K01087,ko:K01194,ko:K01838,ko:K03731,ko:K05342 ko00500,ko01100,map00500,map01100 - R00010,R01555,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 - GH37,GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase HSJS1_k127_3266917_1 1124780.ANNU01000072_gene1068 5.247e-171 554.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia 976|Bacteroidetes E PFAM Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 HSJS1_k127_3271777_3 1267535.KB906767_gene934 3.435e-21 101.0 COG3292@1|root,COG3292@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF1906,VCBS HSJS1_k127_3271777_1 886293.Sinac_1631 1.627e-62 241.0 COG3064@1|root,COG3064@2|Bacteria,2IYZ5@203682|Planctomycetes 203682|Planctomycetes M SpoIVB peptidase S55 - - - - - - - - - - - - Peptidase_S55 HSJS1_k127_3271777_2 1121448.DGI_2309 3.072e-25 115.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2MGC2@213115|Desulfovibrionales 28221|Deltaproteobacteria J Telomere recombination yrdC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC HSJS1_k127_3271777_0 204669.Acid345_0596 5.301e-64 234.0 COG0497@1|root,COG0497@2|Bacteria,3Y2J4@57723|Acidobacteria,2JI9C@204432|Acidobacteriia 204432|Acidobacteriia L May be involved in recombinational repair of damaged DNA - - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N HSJS1_k127_3272481_0 1267535.KB906767_gene1458 8.162e-164 535.0 COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia 204432|Acidobacteriia J Belongs to the class-I aminoacyl-tRNA synthetase family - - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d HSJS1_k127_3273752_2 911045.PSE_3417 7.942e-19 100.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lipoprotein releasing system, transmembrane protein, LolC E family' lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD HSJS1_k127_3273752_0 330214.NIDE2053 2.445e-167 542.0 COG1190@1|root,COG1190@2|Bacteria,3J0AW@40117|Nitrospirae 40117|Nitrospirae J tRNA synthetases class II (D, K and N) lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon HSJS1_k127_3273752_1 378806.STAUR_6369 2.832e-61 223.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2WJW1@28221|Deltaproteobacteria,2YUUB@29|Myxococcales 28221|Deltaproteobacteria F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 HSJS1_k127_3277853_13 326427.Cagg_2332 4.158e-24 113.0 COG0286@1|root,COG0286@2|Bacteria 2|Bacteria V site-specific DNA-methyltransferase (adenine-specific) activity - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,Methylase_S,N6_Mtase HSJS1_k127_3277853_3 68570.DC74_1100 2.425e-93 327.0 COG0169@1|root,COG0169@2|Bacteria 2|Bacteria E shikimate 3-dehydrogenase (NADP+) activity aroE GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K00014,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I,Shikimate_DH,Shikimate_dh_N HSJS1_k127_3277853_12 1121423.JONT01000010_gene1760 1.638e-29 131.0 COG0124@1|root,COG0124@2|Bacteria,1UIUT@1239|Firmicutes,25ESP@186801|Clostridia,267CG@186807|Peptococcaceae 186801|Clostridia J Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His HSJS1_k127_3277853_11 189425.PGRAT_00775 9.329e-40 167.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,26R3C@186822|Paenibacillaceae 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His HSJS1_k127_3277853_1 118166.JH976537_gene3804 1.779e-97 336.0 COG0141@1|root,COG0141@2|Bacteria,1G1I2@1117|Cyanobacteria,1H8MU@1150|Oscillatoriales 1117|Cyanobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh HSJS1_k127_3277853_6 649638.Trad_0439 4.888e-53 213.0 COG0079@1|root,COG0079@2|Bacteria,1WI7K@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HSJS1_k127_3277853_8 903818.KI912268_gene878 9.699e-49 196.0 COG0131@1|root,COG0131@2|Bacteria,3Y3DU@57723|Acidobacteria 57723|Acidobacteria E PFAM Imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD HSJS1_k127_3277853_9 584708.Apau_2181 2.868e-47 183.0 COG0106@1|root,COG0118@1|root,COG0106@2|Bacteria,COG0118@2|Bacteria,3TAX8@508458|Synergistetes 508458|Synergistetes E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth HSJS1_k127_3277853_4 58123.JOFJ01000001_gene3009 1.128e-90 325.0 COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4EFKF@85012|Streptosporangiales 201174|Actinobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth HSJS1_k127_3277853_7 266117.Rxyl_2116 7.11e-51 200.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,2IKKU@201174|Actinobacteria,4CQAR@84995|Rubrobacteria 84995|Rubrobacteria E Histidine biosynthesis bifunctional protein HisIE hisI - 3.5.4.19,3.6.1.31 ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH,PRA-PH HSJS1_k127_3277853_0 1089553.Tph_c26540 1.085e-116 403.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,42FNQ@68295|Thermoanaerobacterales 186801|Clostridia H Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind HSJS1_k127_3277853_5 1382303.JPOM01000001_gene1342 1.891e-65 231.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,2KF9T@204458|Caulobacterales 204458|Caulobacterales EH Anthranilate synthase - - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase HSJS1_k127_3277853_2 555088.DealDRAFT_0421 3.856e-94 328.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42JTG@68298|Syntrophomonadaceae 186801|Clostridia F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 HSJS1_k127_3277853_10 1234364.AMSF01000060_gene967 1.135e-43 169.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1X42P@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS HSJS1_k127_3278444_2 1123239.KB898625_gene530 3.708e-06 59.0 COG0457@1|root,COG0457@2|Bacteria,1VIC7@1239|Firmicutes,4HY13@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - DUF4071 HSJS1_k127_3278444_0 350054.Mflv_4294 4.765e-125 414.0 COG3621@1|root,COG3621@2|Bacteria,2I97F@201174|Actinobacteria,23F3R@1762|Mycobacteriaceae 201174|Actinobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin HSJS1_k127_3278444_1 195250.CM001776_gene3730 1.253e-42 173.0 2BB59@1|root,324MR@2|Bacteria,1GH75@1117|Cyanobacteria,1H3IB@1129|Synechococcus 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_3289286_0 1242864.D187_007721 1.867e-19 100.0 COG3751@1|root,COG3751@2|Bacteria,1PBT5@1224|Proteobacteria,4383D@68525|delta/epsilon subdivisions,2X3DD@28221|Deltaproteobacteria,2YVIF@29|Myxococcales 28221|Deltaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - - HSJS1_k127_3294063_1 682795.AciX8_4715 5.704e-42 159.0 COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia 204432|Acidobacteriia O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome HSJS1_k127_3294063_0 903818.KI912268_gene2181 3.199e-65 248.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_3294708_0 1121930.AQXG01000002_gene2106 3.298e-91 329.0 COG0464@1|root,COG0464@2|Bacteria,4P1Y0@976|Bacteroidetes 976|Bacteroidetes O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA HSJS1_k127_3294708_2 1192034.CAP_6791 4.835e-24 115.0 2C4KT@1|root,340PA@2|Bacteria,1NYVI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3294708_1 479433.Caci_4305 3.128e-59 219.0 COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria 201174|Actinobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran HSJS1_k127_3295285_0 247490.KSU1_D0507 1.571e-217 693.0 COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes 203682|Planctomycetes Q Multicopper oxidase - - - - - - - - - - - - - HSJS1_k127_3295285_1 1211813.CAPH01000017_gene890 5.39e-61 216.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,22U11@171550|Rikenellaceae 976|Bacteroidetes H Domain of unknown function (DUF4301) - - - - - - - - - - - - DUF4301 HSJS1_k127_3296035_0 935567.JAES01000006_gene412 1.314e-211 668.0 COG1506@1|root,COG1506@2|Bacteria,1N75C@1224|Proteobacteria,1RXY1@1236|Gammaproteobacteria,1X51F@135614|Xanthomonadales 135614|Xanthomonadales E Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 HSJS1_k127_3296035_1 861299.J421_1475 1.416e-143 489.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 HSJS1_k127_3296035_2 861299.J421_1476 1.614e-119 415.0 COG2159@1|root,COG2159@2|Bacteria 2|Bacteria E amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 HSJS1_k127_3301087_0 502025.Hoch_2529 3.817e-209 677.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_3301087_1 502025.Hoch_2530 3.194e-87 305.0 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42MPE@68525|delta/epsilon subdivisions,2X630@28221|Deltaproteobacteria,2Z38I@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 HSJS1_k127_3301087_3 395019.Bmul_5523 3.046e-14 86.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VK0G@28216|Betaproteobacteria,1K40E@119060|Burkholderiaceae 28216|Betaproteobacteria M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - - - - - - - - - - OEP HSJS1_k127_3301087_2 1120963.KB894491_gene956 8.758e-30 121.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2PZZK@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran,DUF805 HSJS1_k127_3303131_0 1123073.KB899241_gene2464 5.592e-47 177.0 COG1506@1|root,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - AXE1,Peptidase_S9 HSJS1_k127_3303131_1 1197130.BAFM01000001_gene22 5.039e-28 129.0 COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria 183963|Halobacteria P COG3119 Arylsulfatase A and related enzymes - - - - - - - - - - - - Sulfatase HSJS1_k127_3306495_0 1125863.JAFN01000001_gene3288 5.663e-79 284.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria 28221|Deltaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 HSJS1_k127_3306563_0 880073.Calab_0319 8.181e-107 391.0 COG3604@1|root,COG3604@2|Bacteria 2|Bacteria KT transcription factor binding nifA - - ko:K02584,ko:K11914 ko02020,map02020 - - - ko00000,ko00001,ko02044,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat HSJS1_k127_3306563_8 1487953.JMKF01000023_gene2459 1.068e-18 89.0 2EKGF@1|root,33E6G@2|Bacteria,1G9H5@1117|Cyanobacteria,1HFSJ@1150|Oscillatoriales 1117|Cyanobacteria S Domain of unknown function (DUF1902) - - - - - - - - - - - - DUF1902 HSJS1_k127_3306563_1 338963.Pcar_0737 6.783e-106 355.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,43S80@69541|Desulfuromonadales 28221|Deltaproteobacteria I Carboxyl transferase domain accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans HSJS1_k127_3306563_2 903818.KI912269_gene55 4.355e-90 336.0 COG0515@1|root,COG0515@2|Bacteria 903818.KI912269_gene55|- KLT protein kinase activity - - - - - - - - - - - - - HSJS1_k127_3306563_3 1047013.AQSP01000043_gene53 3.18e-88 300.0 COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg HSJS1_k127_3306563_5 1380390.JIAT01000010_gene4897 7.941e-35 139.0 COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CQCR@84995|Rubrobacteria 84995|Rubrobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC HSJS1_k127_3306563_4 945713.IALB_1358 4.289e-44 170.0 COG0811@1|root,COG0811@2|Bacteria 2|Bacteria U bacteriocin transport exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB HSJS1_k127_3306563_10 1125863.JAFN01000001_gene268 1.469e-08 62.0 COG0848@1|root,COG0848@2|Bacteria,1NN40@1224|Proteobacteria,42XMQ@68525|delta/epsilon subdivisions 1224|Proteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559,ko:K03560 - - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - ExbD HSJS1_k127_3306563_9 1125863.JAFN01000001_gene268 6.731e-16 84.0 COG0848@1|root,COG0848@2|Bacteria,1NN40@1224|Proteobacteria,42XMQ@68525|delta/epsilon subdivisions 1224|Proteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559,ko:K03560 - - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - ExbD HSJS1_k127_3306563_7 204669.Acid345_1862 3.708e-20 100.0 COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia 204432|Acidobacteriia M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - TonB_C HSJS1_k127_3306563_6 1121920.AUAU01000009_gene1889 2.095e-26 119.0 COG0745@1|root,COG0745@2|Bacteria 1121920.AUAU01000009_gene1889|- T phosphorelay signal transduction system - - - - - - - - - - - - - HSJS1_k127_3306563_11 1267535.KB906767_gene2231 1.769e-06 60.0 COG0457@1|root,COG0457@2|Bacteria 1267535.KB906767_gene2231|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_3310222_1 1906.SFRA_03310 5.502e-121 404.0 COG2072@1|root,COG2072@2|Bacteria 2|Bacteria P N,N-dimethylaniline monooxygenase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF4873 HSJS1_k127_3310222_5 1403819.BATR01000181_gene6231 6.323e-66 236.0 COG1117@1|root,COG1117@2|Bacteria,46U5G@74201|Verrucomicrobia,2IWM6@203494|Verrucomicrobiae 203494|Verrucomicrobiae P AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran HSJS1_k127_3310222_3 1396418.BATQ01000046_gene6118 5.936e-91 308.0 COG0581@1|root,COG0581@2|Bacteria,46T8D@74201|Verrucomicrobia 74201|Verrucomicrobia P Binding-protein-dependent transport system inner membrane component pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 HSJS1_k127_3310222_2 497964.CfE428DRAFT_4268 1.278e-91 312.0 COG0573@1|root,COG0573@2|Bacteria,46UNN@74201|Verrucomicrobia 74201|Verrucomicrobia P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 HSJS1_k127_3310222_4 497964.CfE428DRAFT_4267 2.055e-86 306.0 COG0226@1|root,COG0226@2|Bacteria,46U5N@74201|Verrucomicrobia 74201|Verrucomicrobia P PBP superfamily domain - - - - - - - - - - - - PBP_like_2 HSJS1_k127_3310222_0 452637.Oter_0301 6.073e-177 562.0 COG0500@1|root,COG2226@2|Bacteria,46TWV@74201|Verrucomicrobia 2|Bacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 HSJS1_k127_3319960_8 998674.ATTE01000001_gene3794 0.0004732 49.0 COG3678@1|root,COG3678@2|Bacteria 2|Bacteria NPTU ATP-independent chaperone mediated protein folding - - - ko:K06006 - - - - ko00000,ko03110 - - - LTXXQ HSJS1_k127_3319960_6 477974.Daud_1418 2.776e-18 100.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae 186801|Clostridia T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like HSJS1_k127_3319960_7 469383.Cwoe_5514 0.0002932 45.0 COG0642@1|root,COG3850@1|root,COG5278@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,COG5278@2|Bacteria,2INAK@201174|Actinobacteria 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4 HSJS1_k127_3319960_1 880072.Desac_2826 6.777e-74 276.0 COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,42U77@68525|delta/epsilon subdivisions,2WQ4R@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Phosphate-selective porin O and P - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P HSJS1_k127_3319960_2 269799.Gmet_2705 1.942e-65 234.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria,43TYN@69541|Desulfuromonadales 28221|Deltaproteobacteria P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU HSJS1_k127_3319960_5 7739.XP_002600198.1 1.252e-32 136.0 COG0127@1|root,KOG3222@2759|Eukaryota,38DZ3@33154|Opisthokonta,3BE5N@33208|Metazoa,3CSAU@33213|Bilateria,482Q9@7711|Chordata 33208|Metazoa F ITP catabolic process ITPA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006193,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009150,GO:0009154,GO:0009166,GO:0009199,GO:0009203,GO:0009205,GO:0009207,GO:0009259,GO:0009261,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046041,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0051276,GO:0055086,GO:0071704,GO:0071840,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K01519 ko00230,ko00983,ko01100,map00230,map00983,map01100 - R00426,R00720,R01855,R02100,R02720,R03531,R08243 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like HSJS1_k127_3319960_4 391037.Sare_4813 2.198e-50 187.0 COG1309@1|root,COG1309@2|Bacteria,2GJBV@201174|Actinobacteria,4DEMS@85008|Micromonosporales 201174|Actinobacteria K Bacterial transcriptional repressor C-terminal - - - - - - - - - - - - TetR_C_13,TetR_N HSJS1_k127_3319960_3 211165.AJLN01000100_gene4283 9.574e-51 189.0 COG2128@1|root,COG2128@2|Bacteria,1GBGD@1117|Cyanobacteria,1JH2F@1189|Stigonemataceae 1117|Cyanobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD HSJS1_k127_3319960_0 1121448.DGI_1586 3.952e-83 289.0 COG1219@1|root,COG1219@2|Bacteria,1NS53@1224|Proteobacteria,42YDC@68525|delta/epsilon subdivisions,2WU6T@28221|Deltaproteobacteria,2MAA0@213115|Desulfovibrionales 28221|Deltaproteobacteria O AAA domain (Cdc48 subfamily) - - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2 HSJS1_k127_3324973_1 452637.Oter_2603 7.216e-124 417.0 COG2864@1|root,COG2864@2|Bacteria 2|Bacteria C formate dehydrogenase cbcY - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese HSJS1_k127_3324973_2 1382359.JIAL01000001_gene327 4.672e-64 231.0 COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria,2JJ2B@204432|Acidobacteriia 204432|Acidobacteriia C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 HSJS1_k127_3324973_5 1504672.669784458 0.000683 47.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VQ5E@28216|Betaproteobacteria,4ADPF@80864|Comamonadaceae 28216|Betaproteobacteria C Cytochrome C oxidase subunit II, periplasmic domain - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,Cytochrom_C HSJS1_k127_3324973_3 246197.MXAN_5093 2.562e-58 209.0 COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,42Q1E@68525|delta/epsilon subdivisions,2WKG5@28221|Deltaproteobacteria,2Z31H@29|Myxococcales 28221|Deltaproteobacteria E cog0421, spermidine synthase - - - - - - - - - - - - Spermine_synth HSJS1_k127_3324973_0 1280953.HOC_01616 1.14e-174 559.0 COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria,2U464@28211|Alphaproteobacteria,43WAC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2330) - - - - - - - - - - - - DUF2330 HSJS1_k127_3324973_4 314345.SPV1_01842 2.335e-06 49.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GGDEF,HisKA,PAS,PAS_4,PAS_9,Protoglobin,Response_reg HSJS1_k127_3326759_3 1122185.N792_09675 1.182e-20 103.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1X7Y9@135614|Xanthomonadales 135614|Xanthomonadales M Glycosyl transferases group 1 - - - ko:K21001 ko02025,map02025 - - - ko00000,ko00001,ko01003 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 HSJS1_k127_3326759_0 1009370.ALO_00360 2.609e-181 576.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H2FI@909932|Negativicutes 909932|Negativicutes J PFAM tRNA synthetase class II (D K and N), nucleic acid binding OB-fold tRNA helicase-type asnS - 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon HSJS1_k127_3326759_2 589865.DaAHT2_0952 3.433e-50 198.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2MJYR@213118|Desulfobacterales 28221|Deltaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm HSJS1_k127_3326759_1 290397.Adeh_1659 1.431e-158 515.0 COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria 28221|Deltaproteobacteria C NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - - - - - - - - - - Cytochrom_NNT HSJS1_k127_3334208_0 331869.BAL199_19733 7.378e-175 562.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,4BPA9@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 HSJS1_k127_3334208_1 880073.Calab_2261 4.924e-137 459.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2NNZ0@2323|unclassified Bacteria 2|Bacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N HSJS1_k127_3334208_2 204669.Acid345_1684 1.313e-78 274.0 COG0457@1|root,COG0457@2|Bacteria,3Y2M9@57723|Acidobacteria,2JMD8@204432|Acidobacteriia 204432|Acidobacteriia S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_333475_0 1247963.JPHU01000004_gene548 1.281e-165 544.0 COG3227@1|root,COG3227@2|Bacteria,1QXPY@1224|Proteobacteria 1224|Proteobacteria E Fungalysin metallopeptidase (M36) - - - ko:K01417 - - - - ko00000,ko01000,ko01002 - - - CARDB,FTP,PA,Peptidase_M36 HSJS1_k127_3340116_10 478741.JAFS01000001_gene1389 2.149e-10 65.0 COG2856@1|root,COG2856@2|Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - HTH_19,HTH_3,HTH_31,Peptidase_M78 HSJS1_k127_3340116_9 316273.XCV3105 1.116e-14 81.0 2EHW5@1|root,33BMQ@2|Bacteria,1P29Q@1224|Proteobacteria,1T710@1236|Gammaproteobacteria,1X8K7@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - HSJS1_k127_3340116_6 483219.LILAB_03395 1.637e-19 103.0 COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales 28221|Deltaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - HYR,Kelch_4,VCBS HSJS1_k127_3340116_7 251221.35211689 1.239e-17 88.0 2C16Q@1|root,330H3@2|Bacteria,1G90Z@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - HicB,RHH_1 HSJS1_k127_3340116_4 65093.PCC7418_0320 2.299e-46 171.0 COG1569@1|root,COG1569@2|Bacteria,1G5T4@1117|Cyanobacteria 1117|Cyanobacteria S Toxin-antitoxin system, toxin component, PIN family - - - - - - - - - - - - PIN_3 HSJS1_k127_3340116_5 1173024.KI912149_gene6039 8.841e-29 130.0 COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria 1117|Cyanobacteria S SPTR CopG domain protein DNA-binding domain protein - - - - - - - - - - - - BrnA_antitoxin HSJS1_k127_3340116_3 886293.Sinac_5380 1.504e-72 266.0 28PTH@1|root,2ZCER@2|Bacteria,2IZHG@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_3340116_2 886293.Sinac_5379 1.295e-78 276.0 28K3C@1|root,2Z9SH@2|Bacteria,2IXIK@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_3340116_8 83406.HDN1F_17130 1.916e-17 91.0 COG2402@1|root,COG2402@2|Bacteria,1NCFK@1224|Proteobacteria,1SRQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PIN domain - - - ko:K07065 - - - - ko00000 - - - PIN HSJS1_k127_3340116_11 743836.AYNA01000077_gene2820 2.683e-08 62.0 COG4319@1|root,COG4319@2|Bacteria,1RII1@1224|Proteobacteria,2UDKT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440 HSJS1_k127_3340116_1 1121430.JMLG01000002_gene1059 3.736e-104 355.0 COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia,263EX@186807|Peptococcaceae 186801|Clostridia C B12 binding domain - - - - - - - - - - - - B12-binding,Radical_SAM HSJS1_k127_3340116_0 1123366.TH3_02475 0.0 1564.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2JPCA@204441|Rhodospirillales 204441|Rhodospirillales E NAD-specific glutamate dehydrogenase gdhA - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH HSJS1_k127_3340602_0 1328313.DS2_09847 6.683e-163 554.0 COG2372@1|root,COG5276@1|root,COG2372@2|Bacteria,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria,46D9Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S LVIVD repeat - - - - - - - - - - - - Big_5,LVIVD HSJS1_k127_3340602_1 28072.Nos7524_1372 2.036e-11 78.0 COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G1WI@1117|Cyanobacteria 1117|Cyanobacteria Q PFAM Bacterial pre-peptidase C-terminal domain - - - - - - - - - - - - CARDB,Cadherin,Calx-beta,PPC HSJS1_k127_3343930_5 1234364.AMSF01000065_gene2287 0.0007236 47.0 COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,1RRUD@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl Transferase - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_2 HSJS1_k127_3343930_4 234267.Acid_7441 4.238e-20 104.0 COG1216@1|root,COG1216@2|Bacteria,3Y7JI@57723|Acidobacteria 57723|Acidobacteria S Glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 HSJS1_k127_3343930_2 1267535.KB906767_gene3847 3.809e-57 213.0 COG1216@1|root,COG1216@2|Bacteria,3Y7CJ@57723|Acidobacteria 57723|Acidobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_3343930_1 760568.Desku_2097 5.784e-98 347.0 COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,265TC@186807|Peptococcaceae 186801|Clostridia M Domain of unknown function (DUF1972) - - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_3343930_0 404589.Anae109_1412 7.965e-116 389.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 HSJS1_k127_3343930_3 1479235.KK366039_gene1839 4.738e-42 160.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XP6Q@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) - - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA HSJS1_k127_3348527_2 1288494.EBAPG3_10170 9.735e-60 211.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,371UZ@32003|Nitrosomonadales 28216|Betaproteobacteria H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2,5.3.1.9 ko:K00616,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA HSJS1_k127_3348527_1 1242864.D187_009241 9.031e-158 547.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions,2WVIT@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase HSJS1_k127_3348527_0 502025.Hoch_6045 1.289e-251 805.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1Q53R@1224|Proteobacteria,430W1@68525|delta/epsilon subdivisions,2WVP7@28221|Deltaproteobacteria,2YWDG@29|Myxococcales 28221|Deltaproteobacteria KLT Sulfatase-modifying factor enzyme 1 - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - FGE-sulfatase,Pkinase HSJS1_k127_3353837_0 1123253.AUBD01000002_gene1392 1.484e-89 311.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1X48D@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N HSJS1_k127_3353837_1 215803.DB30_5112 1.481e-31 125.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales 28221|Deltaproteobacteria K Transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Sigma54_activat,V4R,XylR_N HSJS1_k127_3355330_0 768671.ThimaDRAFT_3574 3.195e-30 126.0 COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,1S6XI@1236|Gammaproteobacteria,1WYMU@135613|Chromatiales 135613|Chromatiales S Regulatory protein, FmdB - - - - - - - - - - - - Zn-ribbon_8 HSJS1_k127_3355330_1 1396141.BATP01000006_gene5422 1.399e-11 75.0 2EQPS@1|root,33I9Q@2|Bacteria,46X0R@74201|Verrucomicrobia,2IWFG@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - HSJS1_k127_3355330_2 1144275.COCOR_02387 3.312e-06 54.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales 28221|Deltaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1,NUDIX HSJS1_k127_3357997_2 313596.RB2501_05340 1.2e-23 107.0 COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,1I1J9@117743|Flavobacteriia 976|Bacteroidetes J endoribonuclease L-PSP - - - - - - - - - - - - YjgF_endoribonc HSJS1_k127_3357997_1 1121935.AQXX01000049_gene5331 1.063e-23 108.0 COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,1SRB5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - - HSJS1_k127_3357997_0 1121918.ARWE01000001_gene746 2.365e-111 386.0 COG0457@1|root,COG0457@2|Bacteria,1R1JQ@1224|Proteobacteria,4377S@68525|delta/epsilon subdivisions,2WTFW@28221|Deltaproteobacteria,43U9G@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 HSJS1_k127_3358143_3 215803.DB30_2498 1.842e-07 62.0 COG4796@1|root,COG4796@2|Bacteria,1QX5J@1224|Proteobacteria,4310N@68525|delta/epsilon subdivisions,2WWI7@28221|Deltaproteobacteria,2YVID@29|Myxococcales 28221|Deltaproteobacteria U Type ii and iii secretion system protein - - - - - - - - - - - - - HSJS1_k127_3358143_1 204669.Acid345_4328 2.467e-116 381.0 COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria,2JI6S@204432|Acidobacteriia 204432|Acidobacteriia I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N HSJS1_k127_3358143_2 1121939.L861_00295 7.976e-10 72.0 COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1XI7D@135619|Oceanospirillales 135619|Oceanospirillales H COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_6,TPR_8 HSJS1_k127_3358143_0 269799.Gmet_1354 2.057e-162 524.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit HSJS1_k127_3362396_4 1313172.YM304_23620 3.123e-50 195.0 COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria 201174|Actinobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase HSJS1_k127_3362396_0 1382306.JNIM01000001_gene1966 3.257e-160 519.0 COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi 200795|Chloroflexi E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.105,4.1.1.28,4.1.2.27 ko:K01593,ko:K01634 ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034 M00037,M00042,M00100 R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516 RC00264,RC00299,RC00721,RC01266 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC HSJS1_k127_3362396_1 1144275.COCOR_02487 2.041e-84 293.0 COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Thioredoxin - - - - - - - - - - - - SurA_N_3,Thioredoxin_4 HSJS1_k127_3362396_6 1120973.AQXL01000119_gene591 4.971e-15 89.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,278DM@186823|Alicyclobacillaceae 91061|Bacilli L DNA polymerase III, delta subunit holB GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C HSJS1_k127_3362396_3 1232683.ADIMK_4038 1.086e-52 195.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,466N6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin HSJS1_k127_3362396_8 999141.GME_08319 1.39e-05 52.0 COG1396@1|root,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,1XJVH@135619|Oceanospirillales 135619|Oceanospirillales K XRE family transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_3 HSJS1_k127_3362396_10 7994.ENSAMXP00000000402 6.189e-05 54.0 COG0457@1|root,KOG1124@2759|Eukaryota,38C8T@33154|Opisthokonta,3B9HT@33208|Metazoa,3D0W1@33213|Bilateria,489RM@7711|Chordata,490SX@7742|Vertebrata,49RMC@7898|Actinopterygii 33208|Metazoa S Tetratricopeptide repeat domain 25 TTC25 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0007275,GO:0007368,GO:0007389,GO:0007423,GO:0007507,GO:0008150,GO:0009653,GO:0009790,GO:0009799,GO:0009855,GO:0009887,GO:0009987,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032474,GO:0032501,GO:0032502,GO:0042471,GO:0042472,GO:0043583,GO:0044085,GO:0044424,GO:0044464,GO:0044782,GO:0048513,GO:0048562,GO:0048568,GO:0048598,GO:0048731,GO:0048839,GO:0048840,GO:0048856,GO:0060271,GO:0061371,GO:0070925,GO:0071840,GO:0072359,GO:0090596,GO:0120031,GO:0120036 - - - - - - - - - - TPR_12,TPR_2,TPR_7,TPR_8 HSJS1_k127_3362396_9 471854.Dfer_4302 4.554e-05 52.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 HSJS1_k127_3362396_7 1121272.KB903289_gene4164 1.401e-06 59.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4D9E2@85008|Micromonosporales 201174|Actinobacteria T Bacterial transcriptional activator domain - - - - - - - - - - - - BTAD,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C HSJS1_k127_3362396_5 204669.Acid345_2431 2.494e-43 174.0 COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria,2JP24@204432|Acidobacteriia 204432|Acidobacteriia S GHMP kinases C terminal - - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N HSJS1_k127_3362396_2 1047013.AQSP01000140_gene2489 2.945e-81 288.0 COG0739@1|root,COG0739@2|Bacteria,2NPTX@2323|unclassified Bacteria 2|Bacteria M Peptidase family M23 yebA - - - - - - - - - - - OapA,Peptidase_M23 HSJS1_k127_3366657_1 1504319.GM45_0630 3.378e-11 70.0 COG1233@1|root,COG1233@2|Bacteria 2|Bacteria Q all-trans-retinol 13,14-reductase activity - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 HSJS1_k127_3366657_0 1124780.ANNU01000044_gene525 1.944e-290 912.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia 976|Bacteroidetes C Dehydrogenase E1 component pdhB - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C HSJS1_k127_3367700_1 234267.Acid_0687 3.741e-07 62.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria 2|Bacteria S Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_2 HSJS1_k127_3367700_0 1121481.AUAS01000002_gene3510 2.746e-11 76.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,47PE8@768503|Cytophagia 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_3374714_3 521674.Plim_3458 3.393e-30 134.0 COG0824@1|root,COG0824@2|Bacteria,2J02N@203682|Planctomycetes 203682|Planctomycetes S Thioesterase superfamily - - 3.1.2.23 ko:K01075,ko:K07107 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - - 4HBT HSJS1_k127_3374714_4 237368.SCABRO_02153 5.292e-19 93.0 COG0848@1|root,COG0848@2|Bacteria 2|Bacteria U biopolymer transport protein - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD HSJS1_k127_3374714_1 237368.SCABRO_02154 2.917e-43 167.0 COG0811@1|root,COG0811@2|Bacteria,2IZ3U@203682|Planctomycetes 203682|Planctomycetes U MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB HSJS1_k127_3374714_0 573370.DMR_38040 9.381e-209 679.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria 28221|Deltaproteobacteria G K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - Sortilin-Vps10 HSJS1_k127_3374714_2 1394178.AWOO02000027_gene5210 3.367e-31 129.0 COG4976@1|root,COG4976@2|Bacteria,2I4J5@201174|Actinobacteria 201174|Actinobacteria S Methyltransferase - - - - - - - - - - - - - HSJS1_k127_3389804_4 502025.Hoch_2727 0.0002429 45.0 COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales 28221|Deltaproteobacteria L Smr domain - - - - - - - - - - - - Smr HSJS1_k127_3389804_1 1128421.JAGA01000002_gene21 1.518e-19 101.0 COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria 2|Bacteria O heat shock protein binding - - - - - - - - - - - - DUF4388 HSJS1_k127_3389804_3 335543.Sfum_2596 5.314e-15 79.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,42VNC@68525|delta/epsilon subdivisions,2WRIM@28221|Deltaproteobacteria,2MSES@213462|Syntrophobacterales 28221|Deltaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic HSJS1_k127_3389804_2 1463934.JOCF01000017_gene4029 1.538e-19 89.0 2DN2S@1|root,32UI6@2|Bacteria,2IK00@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - HSJS1_k127_3400668_1 1165096.ARWF01000001_gene1808 2.19e-57 213.0 COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,2VTTP@28216|Betaproteobacteria,2KKD2@206350|Nitrosomonadales 206350|Nitrosomonadales M Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 HSJS1_k127_3400668_2 290317.Cpha266_2535 2.564e-36 152.0 COG0400@1|root,COG0400@2|Bacteria,1FF1R@1090|Chlorobi 1090|Chlorobi S PFAM phospholipase Carboxylesterase - - - - - - - - - - - - Abhydrolase_2 HSJS1_k127_3400668_0 880073.Calab_1414 3.508e-66 228.0 COG0388@1|root,COG0388@2|Bacteria,2NPKU@2323|unclassified Bacteria 2|Bacteria S Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase HSJS1_k127_3402887_1 1209984.BN978_03842 1.226e-33 138.0 COG1487@1|root,COG1487@2|Bacteria,2IP2H@201174|Actinobacteria,23AFN@1762|Mycobacteriaceae 201174|Actinobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN HSJS1_k127_3402887_0 1123508.JH636443_gene4835 2.897e-137 443.0 COG0451@1|root,COG0451@2|Bacteria,2IZ0M@203682|Planctomycetes 203682|Planctomycetes GM Polysaccharide biosynthesis protein - - 1.1.1.203 ko:K18981 ko00053,map00053 - R10841 RC00066 ko00000,ko00001,ko01000 - - - Epimerase HSJS1_k127_3402887_3 1125863.JAFN01000001_gene2098 2.196e-05 47.0 COG5573@1|root,COG5573@2|Bacteria,1RKHC@1224|Proteobacteria,43AC4@68525|delta/epsilon subdivisions,2X5S0@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PIN domain - - - - - - - - - - - - PIN HSJS1_k127_3404737_1 1279009.ADICEAN_00953 4.649e-17 83.0 COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,47JX5@768503|Cytophagia 976|Bacteroidetes IQ Short-chain dehydrogenase reductase SDR ykuF - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 HSJS1_k127_3404737_0 1515746.HR45_11315 1.493e-80 298.0 COG3303@1|root,COG3303@2|Bacteria,1NNDS@1224|Proteobacteria 1224|Proteobacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - - HSJS1_k127_3405779_0 1380370.JIBA01000015_gene279 5.477e-27 125.0 COG2132@1|root,COG2132@2|Bacteria,2IDP7@201174|Actinobacteria,4FIUQ@85021|Intrasporangiaceae 201174|Actinobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_3 HSJS1_k127_3410683_0 1198114.AciX9_2492 2.518e-237 810.0 COG4932@1|root,COG4932@2|Bacteria,3Y8E2@57723|Acidobacteria 57723|Acidobacteria M Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg HSJS1_k127_341114_0 748658.KB907313_gene2363 2.273e-84 304.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X2AG@135613|Chromatiales 135613|Chromatiales T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc,PilZ HSJS1_k127_3414655_3 1238182.C882_1291 1.718e-110 374.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2TS0E@28211|Alphaproteobacteria,2JPUG@204441|Rhodospirillales 204441|Rhodospirillales H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C HSJS1_k127_3414655_1 1282876.BAOK01000001_gene2861 4.5e-147 477.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,4BPDK@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA HSJS1_k127_3414655_2 523791.Kkor_0971 1.709e-140 460.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,1XR14@135619|Oceanospirillales 135619|Oceanospirillales E Peptidase M19 - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 HSJS1_k127_3414655_5 583355.Caka_1306 2.302e-24 113.0 2EQTX@1|root,2ZQNF@2|Bacteria,46WYR@74201|Verrucomicrobia,3K8FD@414999|Opitutae 414999|Opitutae - - - - - - - - - - - - - - - HSJS1_k127_3414655_4 313612.L8106_20730 5.383e-57 228.0 COG1401@1|root,COG1401@2|Bacteria,1G2I9@1117|Cyanobacteria,1H8Z9@1150|Oscillatoriales 1117|Cyanobacteria V ATPase associated with various cellular activities, AAA_5 - - - ko:K07452 - - - - ko00000,ko01000,ko02048 - - - AAA_5 HSJS1_k127_3414655_0 448385.sce2299 1.854e-165 533.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWKI@29|Myxococcales 28221|Deltaproteobacteria H Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC HSJS1_k127_3415522_0 1502852.FG94_04531 6.023e-13 83.0 COG2931@1|root,COG2931@2|Bacteria,1PGUW@1224|Proteobacteria,2VY3D@28216|Betaproteobacteria,477AP@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Domain of unknown function (DUF4214) - - - - - - - - - - - - DUF4214 HSJS1_k127_3419908_0 1183438.GKIL_4354 3.002e-157 525.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_3419908_6 330214.NIDE0652 5.384e-19 92.0 2EC1X@1|root,33GB5@2|Bacteria 2|Bacteria - - - - - ko:K21495 - - - - ko00000,ko02048 - - - - HSJS1_k127_3419908_5 671143.DAMO_0814 2.173e-34 136.0 COG1487@1|root,COG1487@2|Bacteria 2|Bacteria S nuclease activity - - - ko:K18828 - - - - ko00000,ko01000,ko02048,ko03016 - - - PIN HSJS1_k127_3419908_4 1356852.N008_12450 1.257e-38 168.0 COG1033@1|root,COG1033@2|Bacteria,4NKTD@976|Bacteroidetes,47UF5@768503|Cytophagia 976|Bacteroidetes S Patched family - - - ko:K07003 - - - - ko00000 - - - MMPL HSJS1_k127_3419908_3 234267.Acid_1354 1.966e-46 175.0 COG2353@1|root,COG2353@2|Bacteria,3Y5DX@57723|Acidobacteria 57723|Acidobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI HSJS1_k127_3419908_2 1265505.ATUG01000001_gene4600 8.051e-101 344.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42NUP@68525|delta/epsilon subdivisions,2WKSD@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM MscS Mechanosensitive ion channel mscS-1 - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel HSJS1_k127_3419908_1 195250.CM001776_gene1918 9.306e-147 487.0 COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1GCX6@1117|Cyanobacteria,1GZFG@1129|Synechococcus 1117|Cyanobacteria EH COG0147 Anthranilate para-aminobenzoate synthases component I - - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind HSJS1_k127_3419908_7 316067.Geob_1385 5.197e-08 55.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales 28221|Deltaproteobacteria S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC HSJS1_k127_3422666_2 204669.Acid345_0553 9.844e-35 142.0 COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia 204432|Acidobacteriia K CarD-like/TRCF domain - - - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF HSJS1_k127_3422666_3 1121920.AUAU01000011_gene207 7.568e-16 88.0 COG4235@1|root,COG4235@2|Bacteria,3Y8SD@57723|Acidobacteria 57723|Acidobacteria O Tetratricopeptide repeat - - - - - - - - - - - - - HSJS1_k127_3422666_4 1156919.QWC_02404 1.225e-05 51.0 2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,3T4XJ@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - ko:K06950 - - - - ko00000 - - - - HSJS1_k127_3422666_1 1232410.KI421412_gene129 1.019e-85 296.0 COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,43TZW@69541|Desulfuromonadales 28221|Deltaproteobacteria S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 HSJS1_k127_3422666_0 1089550.ATTH01000001_gene773 5.406e-184 588.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1FIX7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_3425120_0 1123242.JH636435_gene1474 1.068e-132 437.0 COG2204@1|root,COG2204@2|Bacteria,2IWUX@203682|Planctomycetes 203682|Planctomycetes T CheY-like receiver AAA-type ATPase and DNA-binding domains - - - ko:K11384 ko02020,map02020 M00505 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_3425120_1 909663.KI867150_gene530 1.57e-129 436.0 COG5002@1|root,COG5002@2|Bacteria,1R6WE@1224|Proteobacteria,42P99@68525|delta/epsilon subdivisions,2WK5E@28221|Deltaproteobacteria,2MQ9Q@213462|Syntrophobacterales 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K11383 ko02020,map02020 M00505 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8 HSJS1_k127_3425178_1 1121033.AUCF01000003_gene3411 3.005e-125 413.0 COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,2JQA2@204441|Rhodospirillales 204441|Rhodospirillales M membrane-bound lytic murein transglycosylase mltA - - ko:K08304 - - - - ko00000,ko01000,ko01011 - GH102 - 3D,MltA HSJS1_k127_3425178_0 1000565.METUNv1_04052 4.618e-138 449.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM HSJS1_k127_3425178_3 713586.KB900536_gene2555 8.331e-29 121.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1WYH1@135613|Chromatiales 135613|Chromatiales S PFAM FxsA cytoplasmic membrane protein - - - ko:K07113 - - - - ko00000 - - - FxsA HSJS1_k127_3425178_2 744979.R2A130_3241 2.461e-73 250.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0226 ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 HSJS1_k127_3434539_8 1125863.JAFN01000001_gene996 3.796e-22 107.0 COG1341@1|root,COG1341@2|Bacteria,1NBYH@1224|Proteobacteria,42THE@68525|delta/epsilon subdivisions,2WR2N@28221|Deltaproteobacteria 28221|Deltaproteobacteria S mRNA cleavage and polyadenylation factor CLP1 P-loop - - - ko:K06947 - - - - ko00000,ko01000,ko03009 - - - CLP1_P HSJS1_k127_3434539_7 671143.DAMO_0107 8.225e-23 102.0 COG1487@1|root,COG1487@2|Bacteria,2NRS4@2323|unclassified Bacteria 2|Bacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN HSJS1_k127_3434539_6 929556.Solca_2852 1.248e-24 105.0 COG0791@1|root,COG0791@2|Bacteria,4NM7I@976|Bacteroidetes,1IRW1@117747|Sphingobacteriia 976|Bacteroidetes M Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - - - - - - - - - - Peptidase_C92 HSJS1_k127_3434539_4 926560.KE387023_gene2407 4.106e-49 180.0 COG1832@1|root,COG1832@2|Bacteria 2|Bacteria S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 HSJS1_k127_3434539_2 1287276.X752_11730 3.306e-86 294.0 COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria 28211|Alphaproteobacteria O methyltransferase activity - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT HSJS1_k127_3434539_1 639030.JHVA01000001_gene389 2.38e-101 355.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process cya3 - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - TPR_16,TPR_2,TPR_8,Trans_reg_C HSJS1_k127_3434539_0 518766.Rmar_1842 1.878e-162 529.0 COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1FJQB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S MFS/sugar transport protein - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 HSJS1_k127_3434539_3 1242864.D187_006584 8.08e-50 203.0 COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria 1224|Proteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - - - - - - - - - - Acyltransferase HSJS1_k127_3434539_5 370438.PTH_0927 2.203e-40 154.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae 186801|Clostridia J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C HSJS1_k127_3439229_1 562970.Btus_1602 5.797e-62 226.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,2782Z@186823|Alicyclobacillaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth HSJS1_k127_3439229_3 671143.DAMO_2617 3.242e-22 111.0 COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria 2|Bacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase HSJS1_k127_3439229_0 639030.JHVA01000001_gene3539 2.02e-79 283.0 COG0240@1|root,COG0240@2|Bacteria,3Y3ZH@57723|Acidobacteria,2JINS@204432|Acidobacteriia 204432|Acidobacteriia I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N HSJS1_k127_3439229_2 1121468.AUBR01000039_gene1951 1.035e-52 190.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,42EXT@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans HSJS1_k127_3443385_2 1123288.SOV_1c02290 4.037e-38 145.0 COG1462@1|root,COG1462@2|Bacteria 2|Bacteria M curli production assembly transport component CsgG - - - - - - - - - - - - CsgG HSJS1_k127_3443385_6 543728.Vapar_5432 4.958e-07 55.0 COG5207@1|root,COG5207@2|Bacteria,1RHKT@1224|Proteobacteria,2W3ZK@28216|Betaproteobacteria 28216|Betaproteobacteria O Zn-finger in ubiquitin-hydrolases and other protein - - - - - - - - - - - - zf-UBP HSJS1_k127_3443385_4 926550.CLDAP_28280 1.579e-31 132.0 COG0801@1|root,COG0801@2|Bacteria,2G6YT@200795|Chloroflexi 200795|Chloroflexi H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK HSJS1_k127_3443385_5 344747.PM8797T_30012 9.07e-29 131.0 COG1539@1|root,COG1539@2|Bacteria 2|Bacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 ko:K01633,ko:K07589 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073,R11082 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB HSJS1_k127_3443385_0 671143.DAMO_0882 3.818e-51 194.0 COG1028@1|root,COG1028@2|Bacteria,2NQVU@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 HSJS1_k127_3443385_3 479434.Sthe_2176 5.435e-34 137.0 COG2322@1|root,COG2322@2|Bacteria,2GAA1@200795|Chloroflexi,27YKU@189775|Thermomicrobia 189775|Thermomicrobia S Protein of unknown function (DUF420) - - - ko:K08976 - - - - ko00000 - - - DUF420 HSJS1_k127_3443385_1 573413.Spirs_0268 5.899e-46 173.0 COG0252@1|root,COG0252@2|Bacteria 2|Bacteria EJ asparaginase activity aspG - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase HSJS1_k127_3446625_1 439235.Dalk_1994 1.154e-151 501.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales 28221|Deltaproteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM HSJS1_k127_3446625_3 987059.RBXJA2T_11308 3.195e-14 86.0 COG0526@1|root,COG0526@2|Bacteria,1RHMS@1224|Proteobacteria,2VUYK@28216|Betaproteobacteria,1KMFJ@119065|unclassified Burkholderiales 28216|Betaproteobacteria CO Thioredoxin-like - - 5.3.4.1 ko:K01829 - - - - ko00000,ko01000 - - - Thioredoxin_7 HSJS1_k127_3446625_0 644283.Micau_2110 8.413e-159 520.0 COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4DC9X@85008|Micromonosporales 201174|Actinobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase HSJS1_k127_3446625_2 379066.GAU_0517 1.723e-39 157.0 COG1446@1|root,COG1446@2|Bacteria,1ZTAQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Asparaginase - - 3.5.1.26 ko:K01444 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Asparaginase_2 HSJS1_k127_3452615_1 1123237.Salmuc_04672 5.646e-09 68.0 COG2165@1|root,COG5295@1|root,COG2165@2|Bacteria,COG5295@2|Bacteria,1NDSM@1224|Proteobacteria,2UK7X@28211|Alphaproteobacteria 28211|Alphaproteobacteria UW Chaperone of endosialidase - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Peptidase_S74 HSJS1_k127_3452615_0 1166948.JPZL01000002_gene1858 1.267e-12 81.0 COG0454@1|root,COG0503@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG3087@2|Bacteria,1R2FE@1224|Proteobacteria 1224|Proteobacteria K acetyltransferase - - - - - - - - - - - - - HSJS1_k127_3459828_2 1144275.COCOR_00991 6.362e-11 76.0 COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2YVDU@29|Myxococcales 28221|Deltaproteobacteria M O-antigen ligase like membrane protein - - - ko:K18814 - - - - ko00000,ko02000 9.B.67.1 - - TPR_14,TPR_16,TPR_8,Wzy_C HSJS1_k127_3459828_0 429009.Adeg_0517 1.969e-60 228.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1TP49@1239|Firmicutes,249F1@186801|Clostridia,42G39@68295|Thermoanaerobacterales 186801|Clostridia M PFAM sugar transferase epsL - - ko:K13012 - - - - ko00000,ko01005 - - - Bac_transf HSJS1_k127_3462030_1 448385.sce4361 1.208e-58 214.0 COG4912@1|root,COG4912@2|Bacteria,1RGNQ@1224|Proteobacteria,434G0@68525|delta/epsilon subdivisions,2X8VJ@28221|Deltaproteobacteria,2Z0JW@29|Myxococcales 28221|Deltaproteobacteria L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation HSJS1_k127_3462030_2 448385.sce1083 1.376e-15 79.0 2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales 28221|Deltaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin HSJS1_k127_3462030_0 986075.CathTA2_2223 2.069e-266 837.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C HSJS1_k127_3462030_3 682795.AciX8_2406 3.977e-09 66.0 COG2027@1|root,COG2027@2|Bacteria 2|Bacteria M serine-type D-Ala-D-Ala carboxypeptidase activity - - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - DUF3738,Peptidase_S13 HSJS1_k127_3462543_1 469383.Cwoe_3355 2.955e-44 172.0 COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria 201174|Actinobacteria J glyoxalase III activity - - - - - - - - - - - - AHSA1 HSJS1_k127_3462543_0 1267535.KB906767_gene5241 3.473e-86 301.0 COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria 57723|Acidobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest HSJS1_k127_3464702_2 1121904.ARBP01000002_gene7127 2.423e-29 129.0 COG3386@1|root,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - - - - - - - - - - - SGL HSJS1_k127_3464702_1 471870.BACINT_03487 2.274e-41 164.0 COG2207@1|root,COG2207@2|Bacteria,4NMPG@976|Bacteroidetes,2G2TB@200643|Bacteroidia,4AW45@815|Bacteroidaceae 976|Bacteroidetes K methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) - - - - - - - - - - - - AraC_binding,HTH_18 HSJS1_k127_3464702_0 595460.RRSWK_07231 5.013e-42 159.0 COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_3466454_0 1379270.AUXF01000001_gene2467 2.118e-147 488.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1ZT1A@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Enoyl-CoA hydratase/isomerase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 HSJS1_k127_3469683_0 903818.KI912269_gene113 2.199e-219 698.0 COG0058@1|root,COG0058@2|Bacteria,3Y65H@57723|Acidobacteria 57723|Acidobacteria G PFAM glycosyl transferase, family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase HSJS1_k127_3469683_1 1123242.JH636435_gene2634 3.775e-95 327.0 COG0656@1|root,COG0656@2|Bacteria,2IWVI@203682|Planctomycetes 203682|Planctomycetes S PFAM Aldo keto reductase family - - - - - - - - - - - - Aldo_ket_red HSJS1_k127_3469683_2 388413.ALPR1_20843 1.708e-08 60.0 2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,47N0C@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Phenol_MetA_deg HSJS1_k127_3473582_1 1172186.KB911472_gene5369 9.551e-76 273.0 COG3751@1|root,COG3751@2|Bacteria,2HN62@201174|Actinobacteria 201174|Actinobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 HSJS1_k127_3473582_2 572477.Alvin_3111 5.326e-64 249.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales 135613|Chromatiales G PFAM Fructosamine - - - - - - - - - - - - Fructosamin_kin HSJS1_k127_3473582_3 1142394.PSMK_25770 3.785e-44 171.0 COG0394@1|root,COG0394@2|Bacteria,2J4NI@203682|Planctomycetes 203682|Planctomycetes T Low molecular weight phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc HSJS1_k127_3473582_0 400668.Mmwyl1_4235 6.395e-84 294.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1XI4K@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA HSJS1_k127_3473582_4 81824.XP_001742818.1 5.153e-05 47.0 COG0014@1|root,COG0263@1|root,KOG1154@2759|Eukaryota,KOG4165@2759|Eukaryota,38GA1@33154|Opisthokonta 33154|Opisthokonta E glutamate-5-semialdehyde dehydrogenase activity ALDH18A1 GO:0000052,GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006560,GO:0006561,GO:0006591,GO:0006592,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009266,GO:0009628,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0017084,GO:0018130,GO:0019202,GO:0019240,GO:0019752,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41,2.7.2.11 ko:K00147,ko:K12657 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R00239,R03313 RC00002,RC00043,RC00684 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Aldedh HSJS1_k127_3474354_2 1144275.COCOR_07852 1.423e-38 148.0 arCOG06916@1|root,30456@2|Bacteria,1R83C@1224|Proteobacteria,42UQB@68525|delta/epsilon subdivisions,2WQE5@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF4276) - - - - - - - - - - - - DUF4276 HSJS1_k127_3474354_3 1382356.JQMP01000003_gene1698 1.549e-26 123.0 COG1680@1|root,COG1680@2|Bacteria,2GAJ8@200795|Chloroflexi,27YVH@189775|Thermomicrobia 189775|Thermomicrobia V Beta-lactamase - - - - - - - - - - - - Beta-lactamase HSJS1_k127_3474354_1 671143.DAMO_0002 1.248e-119 393.0 COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria 2|Bacteria M Male sterility protein dfrA - 1.1.1.219,5.1.3.26 ko:K00091,ko:K19997 - - - - ko00000,ko01000 - - - Epimerase HSJS1_k127_3474354_0 1303518.CCALI_00063 3.839e-142 457.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein hpnH - - - - - - - - - - - DUF3463,Fer4_12,Fer4_14,Radical_SAM HSJS1_k127_3478705_1 251221.35210998 3.605e-11 67.0 COG0842@1|root,COG0842@2|Bacteria 2|Bacteria V Transport permease protein - - - - - - - - - - - - - HSJS1_k127_3478705_0 926562.Oweho_2843 1.067e-74 266.0 COG5285@1|root,COG5285@2|Bacteria,4NMHK@976|Bacteroidetes,1IAQP@117743|Flavobacteriia 976|Bacteroidetes Q Phytanoyl-CoA dioxygenase - - - - - - - - - - - - PhyH HSJS1_k127_3487972_1 502025.Hoch_2530 6.344e-44 175.0 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42MPE@68525|delta/epsilon subdivisions,2X630@28221|Deltaproteobacteria,2Z38I@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 HSJS1_k127_3487972_0 1121930.AQXG01000001_gene1203 4.107e-291 930.0 COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_3487972_2 1129794.C427_2778 3.452e-41 162.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,463YW@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_3489883_1 1288484.APCS01000099_gene1357 1.127e-50 183.0 COG0174@1|root,COG0174@2|Bacteria,1WJ0A@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E PFAM Glutamine synthetase, catalytic - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N HSJS1_k127_3489883_0 247490.KSU1_D0506 1.017e-157 513.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cytochrom_D1 HSJS1_k127_349027_4 1123073.KB899242_gene1325 9.016e-09 66.0 COG2133@1|root,COG2133@2|Bacteria 2|Bacteria G pyrroloquinoline quinone binding - - - ko:K12287 - - - - ko00000,ko02044 - - - Big_2,Calx-beta,Laminin_G_3,PA14,VPEP HSJS1_k127_349027_1 234267.Acid_4937 4.285e-125 410.0 COG0387@1|root,COG0387@2|Bacteria,3Y66M@57723|Acidobacteria 57723|Acidobacteria P Sodium/calcium exchanger protein - - - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex HSJS1_k127_349027_0 1469245.JFBG01000019_gene1141 7.139e-130 429.0 COG0665@1|root,COG0665@2|Bacteria,1R49W@1224|Proteobacteria,1SMI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO HSJS1_k127_349027_3 1173028.ANKO01000041_gene3226 6.959e-49 190.0 COG2085@1|root,COG2085@2|Bacteria,1G8DX@1117|Cyanobacteria,1HHG6@1150|Oscillatoriales 1117|Cyanobacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored HSJS1_k127_349027_2 765912.Thimo_2580 5.717e-52 188.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept HSJS1_k127_3499807_1 903818.KI912268_gene2476 5.111e-19 93.0 COG0436@1|root,COG0436@2|Bacteria 2|Bacteria E Aminotransferase bamJ - - - - - - - - - - iSB619.SA_RS10050 Aminotran_1_2 HSJS1_k127_3499807_0 1173028.ANKO01000058_gene3036 1.836e-169 565.0 COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales 1117|Cyanobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_7,PAS_8,PAS_9,Response_reg HSJS1_k127_3499813_2 504472.Slin_5436 1.311e-67 244.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,47KCU@768503|Cytophagia 976|Bacteroidetes H Domain of unknown function (DUF4301) - - - - - - - - - - - - DUF4301 HSJS1_k127_3499813_3 329726.AM1_0403 6.007e-65 246.0 COG1898@1|root,COG1898@2|Bacteria,1G0QA@1117|Cyanobacteria 1117|Cyanobacteria G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom HSJS1_k127_3499813_0 765910.MARPU_12350 8.485e-151 486.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1WX1W@135613|Chromatiales 135613|Chromatiales M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd HSJS1_k127_3499813_1 156889.Mmc1_2096 6.951e-72 252.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA HSJS1_k127_3499813_4 159087.Daro_3430 5.785e-46 172.0 COG0760@1|root,COG0760@2|Bacteria 2|Bacteria O peptidyl-prolyl cis-trans isomerase activity - - 5.2.1.8 ko:K02597,ko:K03770,ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Cu_amine_oxidN1,NPCBM,NifZ,Rotamase,Rotamase_2,SurA_N_3 HSJS1_k127_3505186_1 1382306.JNIM01000001_gene4229 2.027e-116 385.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi 200795|Chloroflexi C FAD linked oxidase domain protein - - - - - - - - - - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8 HSJS1_k127_3505186_2 69395.JQLZ01000001_gene2691 5.17e-05 55.0 2E5IZ@1|root,330AA@2|Bacteria,1N9JX@1224|Proteobacteria,2UVCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3505186_0 935567.JAES01000001_gene2288 0.0 1094.0 COG0308@1|root,COG0308@2|Bacteria,1PTWJ@1224|Proteobacteria,1RZH5@1236|Gammaproteobacteria,1X55X@135614|Xanthomonadales 135614|Xanthomonadales E Peptidase family M1 domain - - - - - - - - - - - - ABC2_membrane_2,Peptidase_M1 HSJS1_k127_351227_3 797302.Halru_1497 6.256e-18 87.0 COG0589@1|root,arCOG02053@2157|Archaea,2XX8Y@28890|Euryarchaeota,23VQJ@183963|Halobacteria 183963|Halobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp HSJS1_k127_351227_0 309807.SRU_0275 1.465e-254 803.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1FIXF@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes G Transketolase, thiamine diphosphate binding domain tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N HSJS1_k127_351227_2 1123073.KB899241_gene2400 2.149e-23 105.0 2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_351227_1 1499967.BAYZ01000163_gene6577 1.2e-47 177.0 COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB HSJS1_k127_3515542_0 756272.Plabr_1286 1.593e-138 463.0 COG1520@1|root,COG1520@2|Bacteria,2IX37@203682|Planctomycetes 203682|Planctomycetes S protein kinase related protein - - - - - - - - - - - - PQQ_2 HSJS1_k127_3515542_1 886293.Sinac_7080 1.331e-48 184.0 COG3832@1|root,COG3832@2|Bacteria,2J0ET@203682|Planctomycetes 203682|Planctomycetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 HSJS1_k127_3515542_2 886293.Sinac_7081 1.053e-39 151.0 COG0640@1|root,COG0640@2|Bacteria,2J3R2@203682|Planctomycetes 203682|Planctomycetes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 HSJS1_k127_3522783_1 445972.ANACOL_02278 2.349e-69 257.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia 186801|Clostridia F Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease HSJS1_k127_3522783_3 1499967.BAYZ01000190_gene3823 1.261e-46 181.0 COG0398@1|root,COG0398@2|Bacteria 2|Bacteria M Pfam SNARE associated Golgi protein - - - - - - - - - - - - DUF547 HSJS1_k127_3522783_0 414996.IL38_11015 4.215e-128 416.0 COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria,407X9@622450|Actinopolysporales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K15975 - - - - ko00000 - - - Glyoxalase HSJS1_k127_3522783_2 696281.Desru_1739 2.299e-55 200.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae 186801|Clostridia S CBS domain-containing protein - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 HSJS1_k127_3522802_0 1038859.AXAU01000002_gene255 6.029e-154 500.0 COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2TYCG@28211|Alphaproteobacteria,3JTS9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Beta-lactamase HSJS1_k127_3522802_1 1121920.AUAU01000006_gene301 4.132e-46 170.0 2BYAB@1|root,32R2Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_3522805_1 485917.Phep_1592 5.134e-21 108.0 COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1INPT@117747|Sphingobacteriia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core HSJS1_k127_3522805_0 204669.Acid345_0539 8.674e-27 126.0 COG1305@1|root,COG1305@2|Bacteria,3Y3A2@57723|Acidobacteria,2JHZ8@204432|Acidobacteriia 204432|Acidobacteriia E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,Transglut_core HSJS1_k127_3529316_0 690850.Desaf_3621 9.045e-159 516.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_3530022_0 1121935.AQXX01000140_gene976 8.228e-56 205.0 COG0300@1|root,COG0300@2|Bacteria 2|Bacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short HSJS1_k127_3530022_1 1123274.KB899406_gene1223 2.241e-29 136.0 COG1033@1|root,COG1033@2|Bacteria,2J5SQ@203691|Spirochaetes 203691|Spirochaetes S COGs COG1033 exporter of the RND superfamily protein - - - ko:K07003 - - - - ko00000 - - - MMPL HSJS1_k127_3530627_1 483219.LILAB_28760 2.674e-29 129.0 COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43CJR@68525|delta/epsilon subdivisions,2X7U3@28221|Deltaproteobacteria,2Z3HT@29|Myxococcales 28221|Deltaproteobacteria M domain protein - - - - - - - - - - - - - HSJS1_k127_3530627_0 314230.DSM3645_05755 1.902e-123 407.0 COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes 203682|Planctomycetes S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_3535087_3 215803.DB30_1942 1.884e-95 333.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2YV42@29|Myxococcales 28221|Deltaproteobacteria E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT HSJS1_k127_3535087_1 521674.Plim_0292 8.138e-199 629.0 COG0044@1|root,COG0044@2|Bacteria,2IWWW@203682|Planctomycetes 203682|Planctomycetes F dihydroorotase - - 3.5.2.2,3.5.2.3,3.5.2.5 ko:K01464,ko:K01465,ko:K01466 ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120 M00046,M00051,M00546 R01993,R02269,R02425,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 HSJS1_k127_3535087_0 477974.Daud_0168 3.744e-238 750.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae 186801|Clostridia H Belongs to the UbiD family - - 4.1.1.61,4.1.1.98 ko:K03182,ko:K16239 ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120 M00117 R01238,R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD HSJS1_k127_3535087_2 408672.NBCG_01888 1.841e-95 324.0 COG0265@1|root,COG0265@2|Bacteria,2ICC4@201174|Actinobacteria 201174|Actinobacteria O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - - HSJS1_k127_3535087_6 1121918.ARWE01000001_gene2210 0.0001963 51.0 COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria 2|Bacteria M chlorophyll binding oprF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03286,ko:K07275 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OprF HSJS1_k127_3535087_4 861299.J421_2417 5.021e-63 219.0 COG1446@1|root,COG1446@2|Bacteria,1ZTAQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Asparaginase - - 3.5.1.26 ko:K01444 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Asparaginase_2 HSJS1_k127_3535544_2 396588.Tgr7_3246 2.863e-25 121.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WX2G@135613|Chromatiales 135613|Chromatiales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran HSJS1_k127_3535544_1 330214.NIDE3755 3.799e-26 124.0 COG3696@1|root,COG3696@2|Bacteria 2|Bacteria P silver ion transport - - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran HSJS1_k127_3535544_4 66429.JOFL01000001_gene4555 9.747e-08 57.0 COG0236@1|root,COG0236@2|Bacteria,2GQS4@201174|Actinobacteria 201174|Actinobacteria IQ Phosphopantetheine attachment site - - - - - - - - - - - - PP-binding HSJS1_k127_3535544_0 44251.PDUR_25675 1.533e-55 218.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,26TIV@186822|Paenibacillaceae 91061|Bacilli S ABC transporter ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH,Pkinase HSJS1_k127_3541041_0 1499967.BAYZ01000009_gene5298 1.161e-280 883.0 COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria 2|Bacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon HSJS1_k127_3541041_3 933262.AXAM01000003_gene2818 7.175e-28 126.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,42TIF@68525|delta/epsilon subdivisions,2WQC4@28221|Deltaproteobacteria,2MKMF@213118|Desulfobacterales 28221|Deltaproteobacteria I CDP-alcohol phosphatidyltransferase pgsA-2 - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf HSJS1_k127_3541041_4 1034347.CAHJ01000010_gene1972 1.931e-09 60.0 COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4HKN1@91061|Bacilli,1ZQS1@1386|Bacillus 91061|Bacilli S RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq HSJS1_k127_3541041_1 335543.Sfum_1920 3.384e-73 280.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MQEE@213462|Syntrophobacterales 28221|Deltaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT HSJS1_k127_3541041_2 338966.Ppro_1379 1.23e-55 221.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,43TMI@69541|Desulfuromonadales 28221|Deltaproteobacteria S TIGRFAM DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B HSJS1_k127_3541807_3 240015.ACP_2301 1.572e-81 274.0 COG1233@1|root,COG1233@2|Bacteria,3Y3RD@57723|Acidobacteria,2JHVY@204432|Acidobacteriia 204432|Acidobacteriia Q Phytoene desaturase - - - - - - - - - - - - Amino_oxidase HSJS1_k127_3541807_1 1238182.C882_1170 2.948e-114 396.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,2TR9T@28211|Alphaproteobacteria,2JVAH@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh HSJS1_k127_3541807_0 1210884.HG799464_gene10819 2.557e-216 688.0 COG1233@1|root,COG1233@2|Bacteria,2IYJC@203682|Planctomycetes 203682|Planctomycetes Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase HSJS1_k127_3541807_2 344747.PM8797T_03414 1.152e-85 294.0 COG5012@1|root,COG5012@2|Bacteria,2IZ1E@203682|Planctomycetes 203682|Planctomycetes L TIGRFAM DNA binding domain protein, excisionase family - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding_2,HTH_17 HSJS1_k127_3544978_3 1158182.KB905021_gene571 7.863e-13 71.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1WVY3@135613|Chromatiales 135613|Chromatiales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_3544978_1 1120966.AUBU01000002_gene2243 9.539e-104 353.0 COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,47N44@768503|Cytophagia 976|Bacteroidetes O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 HSJS1_k127_3544978_0 880073.Calab_1323 3.132e-111 367.0 COG0330@1|root,COG0330@2|Bacteria,2NP2X@2323|unclassified Bacteria 2|Bacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 HSJS1_k127_3544978_4 448385.sce4318 2.047e-11 74.0 COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales 28221|Deltaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding HSJS1_k127_3544978_2 521045.Kole_0092 6.019e-63 220.0 COG0137@1|root,COG0137@2|Bacteria 2|Bacteria E argininosuccinate synthase activity argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.argG,iSB619.SA_RS04675 Arginosuc_synth HSJS1_k127_3546193_2 66429.JOFL01000016_gene132 4.009e-06 57.0 COG2319@1|root,COG4995@1|root,COG2319@2|Bacteria,COG4995@2|Bacteria,2ICQB@201174|Actinobacteria 201174|Actinobacteria E CHAT domain - - - - - - - - - - - - CBM9_1,CHAT,Peptidase_S8,WD40 HSJS1_k127_3546193_0 243090.RB11142 6.976e-128 437.0 COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes 203682|Planctomycetes S beta-propeller repeat - - - - - - - - - - - - PQQ_2 HSJS1_k127_3546193_1 290397.Adeh_1565 3.445e-34 140.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2YYYV@29|Myxococcales 28221|Deltaproteobacteria P transporter of a GTP-driven Fe(2 ) uptake system - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate HSJS1_k127_356807_1 1254432.SCE1572_01620 1.558e-32 140.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2Z144@29|Myxococcales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_356807_0 351160.LRC548 2.184e-50 192.0 COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia 224756|Methanomicrobia M Glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3 HSJS1_k127_3576172_0 1463887.KL589996_gene7840 2.658e-13 80.0 COG4932@1|root,COG4932@2|Bacteria,2GJ4T@201174|Actinobacteria 201174|Actinobacteria M Protein of unknown function (DUF3494) - - - - - - - - - - - - Collagen,DUF3494,TIG HSJS1_k127_3584909_4 1142394.PSMK_26800 1.374e-29 120.0 COG1502@1|root,COG1502@2|Bacteria,2IYFI@203682|Planctomycetes 203682|Planctomycetes I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N HSJS1_k127_3584909_1 309807.SRU_1933 5.251e-154 496.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1FJRD@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 HSJS1_k127_3584909_0 378806.STAUR_1298 2.143e-187 600.0 COG2234@1|root,COG2234@2|Bacteria,1R77P@1224|Proteobacteria,438J4@68525|delta/epsilon subdivisions,2X8TJ@28221|Deltaproteobacteria,2YX3Q@29|Myxococcales 28221|Deltaproteobacteria S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 HSJS1_k127_3584909_3 251221.35213170 5.173e-120 400.0 COG0520@1|root,COG0520@2|Bacteria,1G30B@1117|Cyanobacteria 1117|Cyanobacteria E Cysteine desulfurase family protein - - - - - - - - - - - - Aminotran_5 HSJS1_k127_3584909_2 1499967.BAYZ01000102_gene3561 8.086e-124 431.0 COG4262@1|root,COG4262@2|Bacteria,2NS3W@2323|unclassified Bacteria 2|Bacteria S Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,Spermine_synth HSJS1_k127_3592500_0 357808.RoseRS_1116 5.887e-132 430.0 COG0530@1|root,COG0530@2|Bacteria,2G6GV@200795|Chloroflexi,376V8@32061|Chloroflexia 32061|Chloroflexia P PFAM sodium calcium exchanger membrane region - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex HSJS1_k127_3592500_2 1125863.JAFN01000001_gene957 3.329e-11 65.0 COG2445@1|root,COG2445@2|Bacteria,1NX6S@1224|Proteobacteria,430RY@68525|delta/epsilon subdivisions,2WVSE@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 HSJS1_k127_3592500_1 555779.Dthio_PD0769 9.469e-12 71.0 29MUB@1|root,32NQ5@2|Bacteria,1P1HV@1224|Proteobacteria,43108@68525|delta/epsilon subdivisions,2WWMY@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3594896_3 316274.Haur_2154 5.488e-07 59.0 COG0745@1|root,COG3903@1|root,COG0745@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, LuxR family - - - - - - - - - - - - AAA_22,GerE,NB-ARC,TPR_12,Trans_reg_C HSJS1_k127_3594896_2 314264.ROS217_02565 6.258e-22 108.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,46QK0@74030|Roseovarius 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - BTAD,Trans_reg_C HSJS1_k127_3594896_1 1318628.MARLIPOL_15879 6.924e-37 148.0 2C945@1|root,32W5M@2|Bacteria,1RFGX@1224|Proteobacteria 1224|Proteobacteria - - - - 5.4.4.1 ko:K01865 ko00627,ko01120,map00627,map01120 - - - ko00000,ko00001,ko01000 - - - - HSJS1_k127_3594896_0 715226.ABI_28870 1.342e-44 170.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2KI46@204458|Caulobacterales 204458|Caulobacterales T Histidine kinase - - - - - - - - - - - - His_kinase HSJS1_k127_3607791_2 591001.Acfer_0659 1.656e-24 114.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4H1XM@909932|Negativicutes 909932|Negativicutes D Peptidase M23 envC_1 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 HSJS1_k127_3607791_1 177437.HRM2_11490 2.218e-30 135.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2MJ79@213118|Desulfobacterales 28221|Deltaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 HSJS1_k127_3607791_0 1121033.AUCF01000006_gene4367 3.599e-46 179.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,2TUFD@28211|Alphaproteobacteria,2JRXP@204441|Rhodospirillales 204441|Rhodospirillales S protein conserved in bacteria - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 HSJS1_k127_3607791_3 886293.Sinac_1397 1.011e-18 101.0 COG4485@1|root,COG4485@2|Bacteria,2J25S@203682|Planctomycetes 203682|Planctomycetes S Bacterial membrane protein, YfhO - - - - - - - - - - - - - HSJS1_k127_3616506_0 215803.DB30_6258 1.236e-66 244.0 COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,430H4@68525|delta/epsilon subdivisions,2WVV3@28221|Deltaproteobacteria,2Z01J@29|Myxococcales 28221|Deltaproteobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest HSJS1_k127_3616506_1 1193181.BN10_490002 2.136e-12 80.0 COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4FGBE@85021|Intrasporangiaceae 201174|Actinobacteria K binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase sigM GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_3631112_2 502025.Hoch_0154 9.867e-36 155.0 29XG3@1|root,30J6J@2|Bacteria,1QSSU@1224|Proteobacteria,4355H@68525|delta/epsilon subdivisions,2X95V@28221|Deltaproteobacteria,2Z23G@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3631112_1 756272.Plabr_2694 6.914e-67 236.0 COG2833@1|root,COG2833@2|Bacteria,2J217@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF455) - - - - - - - - - - - - DUF455 HSJS1_k127_3631112_0 1123242.JH636435_gene2360 1.487e-74 267.0 COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes 203682|Planctomycetes S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_3631112_3 266264.Rmet_4697 1.119e-22 111.0 COG2834@1|root,COG2834@2|Bacteria,1RES3@1224|Proteobacteria,2VR9E@28216|Betaproteobacteria,1K73S@119060|Burkholderiaceae 28216|Betaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - - HSJS1_k127_3632571_1 765912.Thimo_0917 1.703e-58 208.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1WX4B@135613|Chromatiales 135613|Chromatiales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 HSJS1_k127_3632571_2 586413.CCDL010000004_gene3374 2.547e-38 158.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,23K7X@182709|Oceanobacillus 91061|Bacilli S Virulence factor BrkB - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB HSJS1_k127_3632571_0 56780.SYN_00323 2.722e-122 404.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42R1V@68525|delta/epsilon subdivisions,2WN7S@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Belongs to the peptidase M50B family - - - - - - - - - - - - CBS,Peptidase_M50,Peptidase_M50B HSJS1_k127_3633379_5 1267533.KB906734_gene4076 1.639e-51 191.0 COG0491@1|root,COG0491@2|Bacteria,3Y3M4@57723|Acidobacteria,2JI7X@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B HSJS1_k127_3633379_6 94624.Bpet3212 2.564e-26 115.0 COG2010@1|root,COG3474@1|root,COG2010@2|Bacteria,COG3474@2|Bacteria,1MW1W@1224|Proteobacteria,2VQSF@28216|Betaproteobacteria,3T721@506|Alcaligenaceae 28216|Betaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 HSJS1_k127_3633379_2 1121918.ARWE01000001_gene3122 3.178e-126 417.0 COG1752@1|root,COG1752@2|Bacteria,1Q4S1@1224|Proteobacteria,42S86@68525|delta/epsilon subdivisions,2WNJA@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin HSJS1_k127_3633379_1 402881.Plav_2105 3.151e-126 417.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TSIV@28211|Alphaproteobacteria,1JMZZ@119043|Rhodobiaceae 28211|Alphaproteobacteria G Fructose-bisphosphate aldolase class-I fbaB - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic HSJS1_k127_3633379_4 869210.Marky_0140 9.112e-72 252.0 COG0566@1|root,COG0566@2|Bacteria,1WID3@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylas_C,SpoU_methylase HSJS1_k127_3633379_3 111780.Sta7437_2615 1.532e-122 416.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1G0FA@1117|Cyanobacteria,3VIK0@52604|Pleurocapsales 1117|Cyanobacteria P TrkA-C domain citT - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C HSJS1_k127_3633379_0 518766.Rmar_2008 4.033e-203 641.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1FJ1P@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HSJS1_k127_3637295_0 656519.Halsa_2097 1.24e-72 255.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WACG@53433|Halanaerobiales 186801|Clostridia S PFAM Permease family - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease HSJS1_k127_3637295_1 869210.Marky_1021 9.82e-24 104.0 COG1324@1|root,COG1324@2|Bacteria,1WKG6@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P PFAM CutA1 divalent ion tolerance protein cutA - - ko:K03926 - - - - ko00000 - - - CutA1 HSJS1_k127_3637295_2 1121934.AUDX01000014_gene1530 3.191e-13 76.0 COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4FPAM@85023|Microbacteriaceae 201174|Actinobacteria L SLBB domain comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB HSJS1_k127_363953_0 671143.DAMO_0158 1.214e-81 292.0 COG4409@1|root,COG4409@2|Bacteria,2NQRQ@2323|unclassified Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity nanA GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal HSJS1_k127_363953_3 742767.HMPREF9456_02987 4.18e-06 49.0 2DPHZ@1|root,3325A@2|Bacteria,4P47G@976|Bacteroidetes,2FS2X@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - HSJS1_k127_363953_1 459495.SPLC1_S540100 2.036e-09 61.0 2E6Q0@1|root,331A9@2|Bacteria,1G8HW@1117|Cyanobacteria,1HCCA@1150|Oscillatoriales 1117|Cyanobacteria S Domain of unknown function (DUF4926) - - - - - - - - - - - - DUF4926 HSJS1_k127_363953_2 32057.KB217478_gene6407 8.969e-07 51.0 2E953@1|root,333DW@2|Bacteria,1G8VT@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_3640161_4 518766.Rmar_0951 9.184e-45 178.0 COG3264@1|root,COG3264@2|Bacteria,4PKDP@976|Bacteroidetes 976|Bacteroidetes M mechanosensitive ion channel mscS - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix HSJS1_k127_3640161_6 1198114.AciX9_0172 4.325e-09 70.0 COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia 204432|Acidobacteriia T Belongs to the anti-sigma-factor antagonist family - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS HSJS1_k127_3640161_3 1111479.AXAR01000021_gene1072 2.561e-66 244.0 COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,27A7C@186823|Alicyclobacillaceae 91061|Bacilli E L-asparaginase II - - - - - - - - - - - - Asparaginase_II HSJS1_k127_3640161_5 1231185.BAMP01000062_gene165 5.973e-10 69.0 COG0607@1|root,COG0607@2|Bacteria,1PFDA@1224|Proteobacteria,2UKXF@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese HSJS1_k127_3640161_0 270374.MELB17_12917 5.752e-305 949.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,469UF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aconitase C-terminal domain - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C HSJS1_k127_3640161_2 313612.L8106_21167 2.27e-138 460.0 COG2823@1|root,COG2823@2|Bacteria,1G9YH@1117|Cyanobacteria 1117|Cyanobacteria S BON domain - - - - - - - - - - - - BON HSJS1_k127_3640161_1 861299.J421_4032 1.427e-146 499.0 COG0457@1|root,COG0457@2|Bacteria 861299.J421_4032|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_364257_0 247490.KSU1_D0506 3.177e-171 558.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cytochrom_D1 HSJS1_k127_3647339_1 1134474.O59_002554 5.455e-60 234.0 COG3642@1|root,COG3642@2|Bacteria,1R7MU@1224|Proteobacteria,1RRK2@1236|Gammaproteobacteria,1FGXR@10|Cellvibrio 1236|Gammaproteobacteria T Lipopolysaccharide kinase (Kdo/WaaP) family - - - - - - - - - - - - Kdo HSJS1_k127_3647339_0 404380.Gbem_0159 3.68e-74 257.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales 28221|Deltaproteobacteria J TIGRFAM ribonuclease, Rne Rng family cafA - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 HSJS1_k127_3648820_2 886293.Sinac_1633 1.788e-58 226.0 COG3386@1|root,COG3386@2|Bacteria,2J56X@203682|Planctomycetes 203682|Planctomycetes G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - HSJS1_k127_3648820_3 1267534.KB906759_gene2022 1.027e-52 192.0 COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia 204432|Acidobacteriia H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like HSJS1_k127_3648820_1 661478.OP10G_1351 5.077e-83 296.0 COG1816@1|root,COG1816@2|Bacteria 2|Bacteria F deaminase activity add2 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 ko:K01488,ko:K18286 ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340 - R01560,R02556,R10695 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase HSJS1_k127_3648820_4 521098.Aaci_0861 7.205e-49 182.0 COG2353@1|root,COG2353@2|Bacteria,1V1NX@1239|Firmicutes,4HFXF@91061|Bacilli 91061|Bacilli S Belongs to the UPF0312 family - - - - - - - - - - - - YceI HSJS1_k127_3648820_0 1144275.COCOR_05413 5.078e-212 679.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria 1224|Proteobacteria U Peptidase m28 - - - - - - - - - - - - PA,Peptidase_M28 HSJS1_k127_3653411_0 1278073.MYSTI_05434 1.436e-147 482.0 COG3227@1|root,COG3227@2|Bacteria,1QXPY@1224|Proteobacteria,43E6J@68525|delta/epsilon subdivisions,2X7H9@28221|Deltaproteobacteria,2Z3GG@29|Myxococcales 28221|Deltaproteobacteria E Fungalysin metallopeptidase (M36) - - - ko:K01417 - - - - ko00000,ko01000,ko01002 - - - FTP,Peptidase_M36 HSJS1_k127_3653411_1 1267533.KB906733_gene3501 4.574e-62 228.0 COG3481@1|root,COG3481@2|Bacteria,3Y38F@57723|Acidobacteria,2JITD@204432|Acidobacteriia 204432|Acidobacteriia S Nucleic acid binding - - - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon HSJS1_k127_3653411_2 1267535.KB906767_gene624 3.949e-23 117.0 COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia 204432|Acidobacteriia S von Willebrand factor, type A - - - - - - - - - - - - VWA,VWA_2 HSJS1_k127_3658536_1 1121920.AUAU01000022_gene2467 1.626e-29 136.0 COG3266@1|root,COG3266@2|Bacteria,3Y4N4@57723|Acidobacteria 57723|Acidobacteria S FecR protein - - - - - - - - - - - - FecR HSJS1_k127_3658536_2 246197.MXAN_7041 8.638e-08 64.0 COG0457@1|root,COG0664@1|root,COG0457@2|Bacteria,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - cNMP_binding HSJS1_k127_3658536_0 1382359.JIAL01000001_gene476 1.996e-46 173.0 COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia 204432|Acidobacteriia J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase HSJS1_k127_3658759_3 596152.DesU5LDRAFT_2631 2.704e-40 172.0 COG5617@1|root,COG5617@2|Bacteria 2|Bacteria M Psort location CytoplasmicMembrane, score - - - - - - - - - - - - YfhO HSJS1_k127_3658759_2 215803.DB30_5543 7.19e-47 183.0 COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2YWS7@29|Myxococcales 28221|Deltaproteobacteria S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans HSJS1_k127_3658759_4 1209989.TepiRe1_0432 9.514e-34 145.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,42EPW@68295|Thermoanaerobacterales 186801|Clostridia E PFAM Extracellular ligand-binding receptor - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 HSJS1_k127_3658759_0 1089550.ATTH01000001_gene276 9.815e-145 472.0 COG0477@1|root,COG2814@2|Bacteria,4PF2D@976|Bacteroidetes,1FK1C@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EGP Transmembrane secretion effector - - - - - - - - - - - - - HSJS1_k127_3658759_1 1499967.BAYZ01000102_gene3561 3.086e-88 304.0 COG4262@1|root,COG4262@2|Bacteria,2NS3W@2323|unclassified Bacteria 2|Bacteria S Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,Spermine_synth HSJS1_k127_3678315_1 649747.HMPREF0083_04814 6.488e-25 109.0 COG1807@1|root,COG1807@2|Bacteria,1TTJ7@1239|Firmicutes 1239|Firmicutes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - ko:K13687 - - - - ko00000,ko01000,ko01003 - GT89 - - HSJS1_k127_3678315_0 391625.PPSIR1_18342 4.07e-41 170.0 2DSXQ@1|root,33HVC@2|Bacteria,1N9KU@1224|Proteobacteria,43CND@68525|delta/epsilon subdivisions,2X7VP@28221|Deltaproteobacteria,2Z3IK@29|Myxococcales 28221|Deltaproteobacteria S Kazal type serine protease inhibitors - - - - - - - - - - - - Kazal_1 HSJS1_k127_3678315_2 1183377.Py04_0995 1.45e-11 69.0 COG1361@1|root,COG1470@1|root,COG1572@1|root,COG3291@1|root,arCOG03439@1|root,arCOG04500@1|root,arCOG07560@1|root,arCOG02079@2157|Archaea,arCOG02087@2157|Archaea,arCOG02532@2157|Archaea,arCOG02546@2157|Archaea,arCOG03439@2157|Archaea,arCOG04500@2157|Archaea,arCOG07560@2157|Archaea 2157|Archaea Q Archaeal Type IV pilin, N-terminal - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CARDB,PKD HSJS1_k127_368259_2 1122176.KB903565_gene3280 3.384e-67 235.0 COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia 976|Bacteroidetes Q amidohydrolase - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 HSJS1_k127_368259_0 1183438.GKIL_2152 2.577e-104 356.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - - - - - - - - - - Amidohydro_1 HSJS1_k127_368259_1 1123242.JH636438_gene5879 1.411e-67 242.0 COG1657@1|root,COG1657@2|Bacteria,2IXWT@203682|Planctomycetes 203682|Planctomycetes I COG1657 Squalene cyclase - - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N HSJS1_k127_3685904_1 483219.LILAB_10130 1.41e-33 146.0 COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1PEJF@1224|Proteobacteria,433Y5@68525|delta/epsilon subdivisions,2X2KM@28221|Deltaproteobacteria,2YXZ5@29|Myxococcales 28221|Deltaproteobacteria KLT AAA ATPase domain - - - - - - - - - - - - AAA_16,Pkinase HSJS1_k127_3685904_0 880073.Calab_0853 1.048e-90 312.0 COG2262@1|root,COG2262@2|Bacteria,2NNWI@2323|unclassified Bacteria 2|Bacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 HSJS1_k127_3685904_2 1479238.JQMZ01000001_gene150 2.825e-09 65.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,43Y5N@69657|Hyphomonadaceae 28211|Alphaproteobacteria CO Thiol disulfide interchange protein tlpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - AhpC-TSA,Redoxin HSJS1_k127_3696185_2 397945.Aave_3452 8.219e-08 62.0 2EJ4N@1|root,33CVW@2|Bacteria,1NJ3Q@1224|Proteobacteria,2W4MZ@28216|Betaproteobacteria 28216|Betaproteobacteria S type III effector - - - - - - - - - - - - - HSJS1_k127_3696185_1 1207063.P24_11797 1.238e-31 141.0 COG1652@1|root,COG1652@2|Bacteria 2|Bacteria S positive regulation of growth rate - - - - - - - - - - - - DUF4157 HSJS1_k127_3696185_0 502025.Hoch_2921 8.168e-58 213.0 COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X39N@28221|Deltaproteobacteria,2Z0CB@29|Myxococcales 28221|Deltaproteobacteria L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp HSJS1_k127_3697537_4 234267.Acid_7688 3.207e-27 116.0 COG1277@1|root,COG1277@2|Bacteria,3Y839@57723|Acidobacteria 57723|Acidobacteria S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - HSJS1_k127_3697537_1 1340493.JNIF01000003_gene1504 9.681e-119 397.0 COG1131@1|root,COG1131@2|Bacteria,3Y4YH@57723|Acidobacteria 57723|Acidobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_3697537_3 1267534.KB906759_gene1820 2.414e-30 139.0 2F2X8@1|root,33VSU@2|Bacteria,3Y7XB@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - HSJS1_k127_3697537_0 1122179.KB890431_gene4241 3.587e-242 761.0 COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - HSJS1_k127_3697537_2 1109445.AGSX01000046_gene3610 3.801e-47 175.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S72R@1236|Gammaproteobacteria,1Z24N@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria I COG2030 Acyl dehydratase - - - - - - - - - - - - MaoC_dehydratas HSJS1_k127_370262_2 1168034.FH5T_14775 1.35e-13 72.0 2EFWM@1|root,339NX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_370262_1 1238182.C882_2377 7.951e-25 113.0 COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2UCCK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG2010 Cytochrome c, mono- and diheme variants - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 HSJS1_k127_370262_0 452662.SJA_C1-12040 7.224e-57 220.0 COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2TW3X@28211|Alphaproteobacteria,2KEME@204457|Sphingomonadales 204457|Sphingomonadales K transcriptional regulator containing an AAA-type ATPase domain and a DNA-binding domain - - - - - - - - - - - - HTH_8,Sigma54_activat,V4R,XylR_N HSJS1_k127_3709747_0 1283284.AZUK01000001_gene579 1.265e-180 571.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1Y3KK@135624|Aeromonadales 135624|Aeromonadales E asparagine synthase (glutamine-hydrolyzing) asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 HSJS1_k127_3709747_1 653733.Selin_0242 2.949e-27 114.0 COG1669@1|root,COG1669@2|Bacteria 2|Bacteria S nucleotidyltransferase activity - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 HSJS1_k127_371241_2 90813.JQMT01000001_gene2143 6.916e-14 85.0 2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,1SBZ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_371241_0 690850.Desaf_0251 2.125e-150 509.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2M86M@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 51 mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iAF987.Gmet_0354 PCB_OB,Transgly,Transpeptidase HSJS1_k127_371241_1 309801.trd_1549 4.86e-121 409.0 COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia 189775|Thermomicrobia L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB HSJS1_k127_3715673_1 1238182.C882_0401 1.675e-71 255.0 COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VFY5@28211|Alphaproteobacteria,2JRKP@204441|Rhodospirillales 204441|Rhodospirillales E Putative serine dehydratase domain - - - - - - - - - - - - Ala_racemase_N,D-ser_dehydrat HSJS1_k127_3715673_2 330214.NIDE0511 2.729e-58 212.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase pmtA - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 HSJS1_k127_3715673_3 1123278.KB893418_gene4052 2.715e-52 192.0 COG2128@1|root,COG2128@2|Bacteria,4NNYF@976|Bacteroidetes,47US0@768503|Cytophagia 976|Bacteroidetes S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD HSJS1_k127_3715673_4 1286093.C266_11785 1.052e-20 102.0 COG1075@1|root,COG1075@2|Bacteria,1N3FV@1224|Proteobacteria,2WFKG@28216|Betaproteobacteria,1K0BZ@119060|Burkholderiaceae 28216|Betaproteobacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4,PGAP1 HSJS1_k127_3715673_0 713587.THITH_07385 1.054e-137 447.0 COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria 1224|Proteobacteria S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_3718040_2 1229780.BN381_330005 5.139e-16 83.0 2B3ZZ@1|root,31WQ4@2|Bacteria,2GXQG@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - HSJS1_k127_3718040_0 204669.Acid345_0030 5.152e-84 289.0 COG0042@1|root,COG0042@2|Bacteria,3Y3XE@57723|Acidobacteria,2JI1U@204432|Acidobacteriia 204432|Acidobacteriia J synthase - - - - - - - - - - - - Dus HSJS1_k127_3718040_1 1329516.JPST01000005_gene1396 4.48e-38 151.0 COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,27BS9@186824|Thermoactinomycetaceae 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25 HSJS1_k127_373188_1 1121920.AUAU01000028_gene1372 5.582e-32 143.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_373188_0 266117.Rxyl_3138 1.262e-85 289.0 COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria 84995|Rubrobacteria L Radical SAM - - - - - - - - - - - - Radical_SAM HSJS1_k127_3734009_1 1283300.ATXB01000001_gene738 1.533e-19 91.0 COG1833@1|root,COG1833@2|Bacteria,1N8Y1@1224|Proteobacteria,1SDIB@1236|Gammaproteobacteria,1XGWK@135618|Methylococcales 135618|Methylococcales S Domain of unknown function DUF123 - - - - - - - - - - - - DUF123 HSJS1_k127_3734009_0 1196323.ALKF01000197_gene2234 1.657e-50 189.0 COG4099@1|root,COG4099@2|Bacteria,1V9NT@1239|Firmicutes,4IPZS@91061|Bacilli,276CT@186822|Paenibacillaceae 91061|Bacilli S Esterase PHB depolymerase - - - - - - - - - - - - Peptidase_S9 HSJS1_k127_3734009_2 234267.Acid_1402 4.938e-05 56.0 COG2304@1|root,COG2304@2|Bacteria,3Y99W@57723|Acidobacteria 57723|Acidobacteria S von Willebrand factor type A domain - - - - - - - - - - - - VWA,VWA_2 HSJS1_k127_3735313_4 253839.SSNG_07496 2.26e-05 53.0 COG3321@1|root,COG3321@2|Bacteria 2|Bacteria Q synthase - - - - - - - - - - - - Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HSJS1_k127_3735313_1 1267535.KB906767_gene4734 1.94e-138 456.0 COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria,2JHIQ@204432|Acidobacteriia 204432|Acidobacteriia J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e HSJS1_k127_3735313_3 502025.Hoch_2488 1.778e-20 107.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria,2YVUJ@29|Myxococcales 28221|Deltaproteobacteria L Uncharacterised protein family UPF0102 - - - ko:K07460 - - - - ko00000 - - - UPF0102 HSJS1_k127_3735313_0 215803.DB30_5064 2.731e-232 769.0 COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1Q712@1224|Proteobacteria,433SV@68525|delta/epsilon subdivisions,2WYAY@28221|Deltaproteobacteria,2YXT0@29|Myxococcales 28221|Deltaproteobacteria E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,Transglut_core HSJS1_k127_3735313_2 861299.J421_4031 2.561e-39 166.0 COG4658@1|root,COG4658@2|Bacteria 2|Bacteria C electron transport chain - - 1.6.5.8 ko:K00347,ko:K03614 - - - - ko00000,ko01000 - - - Complex1_51K,NQR2_RnfD_RnfE,RnfC_N HSJS1_k127_3735467_6 1121920.AUAU01000004_gene627 5.295e-08 57.0 COG1538@1|root,COG1538@2|Bacteria,3Y3BF@57723|Acidobacteria 57723|Acidobacteria MU outer membrane efflux protein - - - - - - - - - - - - OEP HSJS1_k127_3735467_3 1047013.AQSP01000042_gene408 1.155e-61 235.0 COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family macA - - ko:K02005,ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP HSJS1_k127_3735467_1 1121920.AUAU01000004_gene795 1.613e-93 312.0 COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria 57723|Acidobacteria V ABC transporter - - - - - - - - - - - - ABC_tran HSJS1_k127_3735467_2 1384056.N787_08305 5.087e-91 313.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1X4UK@135614|Xanthomonadales 135614|Xanthomonadales V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_3735467_7 59894.ENSFALP00000009487 0.0002856 53.0 KOG1127@1|root,KOG1127@2759|Eukaryota,38B8M@33154|Opisthokonta,3BCFI@33208|Metazoa,3CZ85@33213|Bilateria,486QB@7711|Chordata,48VXY@7742|Vertebrata,4GTHG@8782|Aves 33208|Metazoa A Tetratricopeptide repeat protein 37 TTC37 GO:0000288,GO:0000291,GO:0000785,GO:0000956,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0034655,GO:0035327,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043928,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0055087,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - ko:K12600 ko03018,map03018 M00392 - - ko00000,ko00001,ko00002,ko03019 - - - TPR_16,TPR_2,TPR_8 HSJS1_k127_3735467_4 234267.Acid_7677 1.889e-56 203.0 COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria 57723|Acidobacteria K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_3735467_0 1379698.RBG1_1C00001G0607 2.595e-102 363.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_2,TPR_8 HSJS1_k127_3737409_3 1379270.AUXF01000004_gene3009 2.241e-29 126.0 COG2318@1|root,COG2318@2|Bacteria,1ZU3G@142182|Gemmatimonadetes 142182|Gemmatimonadetes S DinB superfamily - - - - - - - - - - - - DinB_2 HSJS1_k127_3737409_1 498761.HM1_2174 6.74e-86 299.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia 186801|Clostridia U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N HSJS1_k127_3737409_0 264732.Moth_0915 1.197e-105 355.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales 186801|Clostridia H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 HSJS1_k127_3737409_2 644966.Tmar_1416 5.321e-48 179.0 COG0108@1|root,COG0307@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0307@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WCXY@538999|Clostridiales incertae sedis 186801|Clostridia H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS10830 DHBP_synthase,GTP_cyclohydro2 HSJS1_k127_3738176_0 861299.J421_1457 2.366e-201 644.0 COG2274@1|root,COG2274@2|Bacteria,1ZSX6@142182|Gemmatimonadetes 142182|Gemmatimonadetes V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran HSJS1_k127_3738176_2 246197.MXAN_3625 1.122e-47 189.0 COG2308@1|root,COG2308@2|Bacteria 2|Bacteria S glutamate-cysteine ligase activity - - - - - - - - - - - - CP_ATPgrasp_2,GSP_synth HSJS1_k127_3738176_1 1297865.APJD01000015_gene3469 7.709e-58 215.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_6,DLH,Thioesterase HSJS1_k127_374254_1 378806.STAUR_4830 1.565e-46 183.0 COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2YUBN@29|Myxococcales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM HSJS1_k127_374254_0 694427.Palpr_2132 6.984e-68 250.0 COG0641@1|root,COG0641@2|Bacteria 2|Bacteria C radical SAM - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM HSJS1_k127_3742701_1 1179773.BN6_76360 6.495e-37 151.0 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales 201174|Actinobacteria M glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2 HSJS1_k127_3742701_0 1128421.JAGA01000002_gene1117 5.075e-61 231.0 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria 2|Bacteria L Glycosyltransferase like family 2 gumK - 2.4.1.264 ko:K07011,ko:K13659 - - R09732 RC00005,RC00049 ko00000,ko01000,ko01003 - GT70 - Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2 HSJS1_k127_3742701_2 1480694.DC28_03280 7.108e-36 145.0 COG0393@1|root,COG0393@2|Bacteria 2|Bacteria S Putative heavy-metal-binding - - - - - - - - - - - - YbjQ_1 HSJS1_k127_3742701_5 1122134.KB893650_gene13 2.368e-11 72.0 COG5660@1|root,COG5660@2|Bacteria,1NCWT@1224|Proteobacteria,1SDFE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative zinc-finger - - - - - - - - - - - - zf-HC2 HSJS1_k127_3742701_3 1226322.HMPREF1545_01785 1.795e-23 108.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,2N772@216572|Oscillospiraceae 186801|Clostridia K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_3742701_4 1223521.BBJX01000001_gene924 4.734e-13 73.0 COG2227@1|root,COG2227@2|Bacteria,1NBIU@1224|Proteobacteria,2WHYX@28216|Betaproteobacteria 28216|Betaproteobacteria H Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_23 HSJS1_k127_3745237_2 1229172.JQFA01000002_gene2579 1.274e-44 165.0 COG1853@1|root,COG1853@2|Bacteria,1G4QZ@1117|Cyanobacteria 1117|Cyanobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct HSJS1_k127_3745237_0 41431.PCC8801_0038 2.82e-112 382.0 COG0624@1|root,COG0624@2|Bacteria,1G3WM@1117|Cyanobacteria,3KG7E@43988|Cyanothece 1117|Cyanobacteria E peptidase dimerisation domain protein - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 HSJS1_k127_3745237_3 1173028.ANKO01000030_gene3327 1.04e-31 126.0 COG2442@1|root,COG2442@2|Bacteria,1G7T6@1117|Cyanobacteria,1HC34@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 HSJS1_k127_3745237_4 1499967.BAYZ01000141_gene6156 8.767e-28 115.0 COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - Mut7-C HSJS1_k127_3745237_1 1121930.AQXG01000003_gene2590 5.658e-68 235.0 COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,1IRYN@117747|Sphingobacteriia 976|Bacteroidetes P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,TrkA_C HSJS1_k127_3746292_1 1089550.ATTH01000001_gene773 9.062e-113 373.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1FIX7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HSJS1_k127_3746292_2 1089550.ATTH01000001_gene772 4.04e-99 344.0 COG0845@1|root,COG0845@2|Bacteria,4PEYA@976|Bacteroidetes,1FJUQ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 HSJS1_k127_3746292_3 1499967.BAYZ01000194_gene3127 1.843e-78 269.0 COG1994@1|root,COG1994@2|Bacteria 2|Bacteria S metallopeptidase activity ywhC - - - - - - - - - - - Peptidase_M50 HSJS1_k127_3746292_0 414684.RC1_1181 1.661e-137 470.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,2TRVE@28211|Alphaproteobacteria,2JTK9@204441|Rhodospirillales 204441|Rhodospirillales EU Dipeptidyl peptidase IV (DPP IV) N-terminal region - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 HSJS1_k127_3746292_5 886293.Sinac_4351 2.251e-27 126.0 COG3595@1|root,COG4219@1|root,COG3595@2|Bacteria,COG4219@2|Bacteria,2J24Z@203682|Planctomycetes 203682|Planctomycetes KT Antirepressor regulating drug resistance - - - - - - - - - - - - Peptidase_M56 HSJS1_k127_3746292_4 204669.Acid345_3065 1.817e-60 214.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO HSJS1_k127_3751085_4 1384054.N790_12820 3.914e-61 224.0 COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 HSJS1_k127_3751085_0 504728.K649_03245 1.659e-157 514.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) - - 1.14.15.7 ko:K00499 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A HSJS1_k127_3751085_7 56780.SYN_00229 3.329e-05 51.0 COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,42V4W@68525|delta/epsilon subdivisions,2WR6H@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM Sulfate transporter antisigma-factor antagonist STAS rsbV - - ko:K04749 - - - - ko00000,ko03021 - - - STAS HSJS1_k127_3751085_3 671143.DAMO_1345 4.919e-75 266.0 COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria 2|Bacteria O Thioredoxin - - - - - - - - - - - - SurA_N_3,Thioredoxin_4 HSJS1_k127_3751085_6 768671.ThimaDRAFT_3191 5.757e-28 125.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8,Trans_reg_C HSJS1_k127_3751085_1 309807.SRU_0883 4.01e-112 382.0 COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1FK5M@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 HSJS1_k127_3751085_5 1128421.JAGA01000002_gene84 2.981e-38 153.0 COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria 2|Bacteria S 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 HSJS1_k127_3751085_2 335543.Sfum_0290 1.88e-93 325.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MSIQ@213462|Syntrophobacterales 28221|Deltaproteobacteria M Transglycosylase mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H HSJS1_k127_3756523_1 1283299.AUKG01000005_gene166 2.333e-20 96.0 COG0346@1|root,COG0346@2|Bacteria,2I5X0@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 HSJS1_k127_3756523_0 309807.SRU_2034 8.384e-129 426.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EU Prolyl oligopeptidase family - - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 HSJS1_k127_3762194_1 1144275.COCOR_01889 2.487e-130 431.0 COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,42P2M@68525|delta/epsilon subdivisions,2WJIM@28221|Deltaproteobacteria 28221|Deltaproteobacteria S homolog of phage Mu protein gp47 - - - - - - - - - - - - Baseplate_J HSJS1_k127_3762194_2 269799.Gmet_1142 2.587e-111 380.0 COG3292@1|root,COG3292@2|Bacteria,1QMJ4@1224|Proteobacteria,42RQF@68525|delta/epsilon subdivisions,2WNII@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Two component regulator propeller - - - - - - - - - - - - Tail_P2_I HSJS1_k127_3762194_0 269799.Gmet_1144 1.956e-145 493.0 COG3391@1|root,COG3391@2|Bacteria,1QWR8@1224|Proteobacteria,43CAC@68525|delta/epsilon subdivisions,2X7KW@28221|Deltaproteobacteria 28221|Deltaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - HSJS1_k127_3762194_3 690850.Desaf_3555 3.028e-36 159.0 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1N0FZ@1224|Proteobacteria,42TXS@68525|delta/epsilon subdivisions 1224|Proteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar HSJS1_k127_3768206_1 1313421.JHBV01000027_gene1726 3.642e-52 195.0 COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1IU82@117747|Sphingobacteriia 976|Bacteroidetes M involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_3768206_3 743525.TSC_c16700 4.082e-39 151.0 COG3255@1|root,COG3255@2|Bacteria,1WMIK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K SCP-2 sterol transfer family - - - - - - - - - - - - SCP2 HSJS1_k127_3768206_0 383372.Rcas_3780 3.083e-103 353.0 COG0208@1|root,COG0208@2|Bacteria,2G610@200795|Chloroflexi,3761D@32061|Chloroflexia 32061|Chloroflexia F PFAM ribonucleotide reductase - - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm HSJS1_k127_3768206_5 1123242.JH636435_gene1547 1.171e-06 54.0 COG0457@1|root,COG0457@2|Bacteria,2IYMF@203682|Planctomycetes 203682|Planctomycetes M Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 HSJS1_k127_3769313_0 573370.DMR_08620 5.406e-88 314.0 COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria,2MA00@213115|Desulfovibrionales 28221|Deltaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_6 HSJS1_k127_3779376_0 204669.Acid345_1995 5.372e-233 743.0 COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia 204432|Acidobacteriia J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 HSJS1_k127_3779376_4 1232410.KI421413_gene522 1.134e-31 130.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,43SNS@69541|Desulfuromonadales 28221|Deltaproteobacteria J Ribosomal_S15 rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 HSJS1_k127_3779376_3 555088.DealDRAFT_2421 8.306e-50 197.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,42JUU@68298|Syntrophomonadaceae 186801|Clostridia J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N HSJS1_k127_3779376_2 867903.ThesuDRAFT_00231 6.754e-66 238.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WCIW@538999|Clostridiales incertae sedis 186801|Clostridia S DHH family nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 HSJS1_k127_3779376_5 290398.Csal_3073 3.787e-18 93.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XKKG@135619|Oceanospirillales 135619|Oceanospirillales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA HSJS1_k127_3779376_6 1157637.KB892125_gene535 4.15e-12 70.0 COG1550@1|root,COG1550@2|Bacteria,2IQW4@201174|Actinobacteria 201174|Actinobacteria S protein conserved in bacteria - - - ko:K09764 - - - - ko00000 - - - DUF503 HSJS1_k127_3779376_1 234267.Acid_5181 3.515e-113 372.0 COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,3Y3UG@57723|Acidobacteria 57723|Acidobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N HSJS1_k127_378063_3 518766.Rmar_1486 2.683e-85 310.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FINA@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Transketolase, pyrimidine binding domain bfmBA - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C HSJS1_k127_378063_8 56107.Cylst_1286 2.131e-20 96.0 COG1017@1|root,COG2114@1|root,COG5000@1|root,COG1017@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria,1G2WP@1117|Cyanobacteria,1HKCN@1161|Nostocales 1117|Cyanobacteria CT Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Globin,Guanylate_cyc,HAMP,dCache_1 HSJS1_k127_378063_2 7739.XP_002596423.1 1.682e-88 298.0 COG3340@1|root,2QR7X@2759|Eukaryota,39DGA@33154|Opisthokonta,3BC18@33208|Metazoa,3CWYN@33213|Bilateria,484TW@7711|Chordata 33208|Metazoa E Peptidase family S51 - GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 HSJS1_k127_378063_1 329726.AM1_4986 3.902e-106 364.0 COG2357@1|root,COG2357@2|Bacteria 2|Bacteria S guanosine tetraphosphate metabolic process relA - 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT HSJS1_k127_378063_6 1502850.FG91_01185 2.82e-38 158.0 COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,2UBFR@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 HSJS1_k127_378063_10 263358.VAB18032_06985 1.757e-10 72.0 COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria,4DBWS@85008|Micromonosporales 201174|Actinobacteria F P-aminobenzoate N-oxygenase AurF - - - - - - - - - - - - AurF HSJS1_k127_378063_4 522306.CAP2UW1_3910 1.495e-84 305.0 COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria 28216|Betaproteobacteria IQ amp-dependent synthetase and ligase - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding HSJS1_k127_378063_11 1382304.JNIL01000001_gene649 1.611e-09 61.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding HSJS1_k127_378063_7 1304275.C41B8_14900 2.79e-36 147.0 COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SEZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF374) - - - ko:K09778 - - - - ko00000 - - - DUF374 HSJS1_k127_378063_0 344747.PM8797T_19106 7.151e-144 470.0 COG1520@1|root,COG1520@2|Bacteria,2IWWY@203682|Planctomycetes 203682|Planctomycetes S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_378063_9 717605.Theco_1585 2.261e-19 93.0 2E9CG@1|root,333K5@2|Bacteria,1VJEP@1239|Firmicutes,4HQ44@91061|Bacilli,275YM@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - HSJS1_k127_378063_5 243090.RB12562 7.196e-58 218.0 COG1520@1|root,COG1520@2|Bacteria,2J2RN@203682|Planctomycetes 203682|Planctomycetes S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_378769_0 1297742.A176_03040 2.917e-228 737.0 COG3227@1|root,COG3227@2|Bacteria,1QXPY@1224|Proteobacteria,43E6J@68525|delta/epsilon subdivisions,2X7H9@28221|Deltaproteobacteria,2Z3GG@29|Myxococcales 28221|Deltaproteobacteria E Fungalysin metallopeptidase (M36) - - - ko:K01417 - - - - ko00000,ko01000,ko01002 - - - FTP,Peptidase_M36 HSJS1_k127_378769_1 717606.PaecuDRAFT_4345 6.786e-12 79.0 COG4124@1|root,COG5297@1|root,COG4124@2|Bacteria,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase family 6 guxA - 3.2.1.91 ko:K19668 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6 - CBM_3,Glyco_hydro_6,fn3 HSJS1_k127_3793143_1 187303.BN69_2999 4.996e-61 219.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,36ZVX@31993|Methylocystaceae 28211|Alphaproteobacteria C Domain of unknown function (DUF4070) - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM HSJS1_k127_3793143_2 502025.Hoch_6617 3.086e-51 190.0 COG1994@1|root,COG1994@2|Bacteria,1QXF3@1224|Proteobacteria,43C6H@68525|delta/epsilon subdivisions,2X7GR@28221|Deltaproteobacteria,2Z2N5@29|Myxococcales 28221|Deltaproteobacteria S Peptidase M50B-like - - - - - - - - - - - - Peptidase_M50B HSJS1_k127_3793143_3 1144275.COCOR_06998 4.198e-32 147.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,42P9S@68525|delta/epsilon subdivisions,2WJI7@28221|Deltaproteobacteria,2YTSQ@29|Myxococcales 28221|Deltaproteobacteria H CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_7,TPR_8 HSJS1_k127_3793143_4 10141.ENSCPOP00000010381 7.73e-19 96.0 COG5640@1|root,KOG3627@2759|Eukaryota,38CGF@33154|Opisthokonta,3BGUI@33208|Metazoa,3CRKT@33213|Bilateria,480CJ@7711|Chordata,48XYZ@7742|Vertebrata,3JCE1@40674|Mammalia,35F58@314146|Euarchontoglires,4Q9JD@9989|Rodentia 33208|Metazoa O Belongs to the peptidase S1 family KLK13 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0008544,GO:0009888,GO:0009913,GO:0009987,GO:0012501,GO:0012505,GO:0016787,GO:0017171,GO:0019538,GO:0030141,GO:0030154,GO:0030216,GO:0030855,GO:0031410,GO:0031424,GO:0031982,GO:0032501,GO:0032502,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043588,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048513,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050803,GO:0050807,GO:0051128,GO:0060429,GO:0065007,GO:0065008,GO:0070011,GO:0070268,GO:0071704,GO:0097708,GO:0099174,GO:0099503,GO:0140096,GO:1901564,GO:2000331 3.4.21.119,3.4.21.4 ko:K01312,ko:K09463,ko:K09640,ko:K17495,ko:K20676 ko04080,ko04624,ko04972,ko04974,ko05164,map04080,map04624,map04972,map04974,map05164 - - - ko00000,ko00001,ko01000,ko01002,ko01009,ko04147 - - - Trypsin HSJS1_k127_3793143_0 243090.RB11673 2.844e-168 537.0 COG0481@1|root,COG0481@2|Bacteria,2J23Y@203682|Planctomycetes 203682|Planctomycetes J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner - - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,LepA_C HSJS1_k127_3796305_1 309803.CTN_1664 5.822e-73 255.0 COG0182@1|root,COG0182@2|Bacteria,2GCAP@200918|Thermotogae 200918|Thermotogae J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B HSJS1_k127_3796305_0 240015.ACP_1006 2.652e-143 479.0 COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia 204432|Acidobacteriia E Cys/Met metabolism PLP-dependent enzyme - - 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP HSJS1_k127_3796305_2 465515.Mlut_04340 1.725e-05 53.0 COG1396@1|root,COG1396@2|Bacteria,2INQP@201174|Actinobacteria,1W9BT@1268|Micrococcaceae 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 HSJS1_k127_3797024_1 1121033.AUCF01000019_gene3730 2.611e-42 162.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2U7NP@28211|Alphaproteobacteria,2JS9M@204441|Rhodospirillales 204441|Rhodospirillales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase HSJS1_k127_3797024_0 926569.ANT_22850 1.98e-308 982.0 COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi 200795|Chloroflexi J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 HSJS1_k127_3799531_5 1192034.CAP_6447 1.568e-13 81.0 COG3518@1|root,COG3518@2|Bacteria,1Q2KF@1224|Proteobacteria,433UA@68525|delta/epsilon subdivisions,2X3H1@28221|Deltaproteobacteria,2YW24@29|Myxococcales 28221|Deltaproteobacteria S Gene 25-like lysozyme - - - ko:K11897 - M00334 - - ko00000,ko00002,ko02044 - - - GPW_gp25 HSJS1_k127_3799531_3 1550073.JROH01000002_gene741 4.428e-55 197.0 COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2U1NF@28211|Alphaproteobacteria,2K4XV@204457|Sphingomonadales 204457|Sphingomonadales S Type VI secretion system effector, Hcp - - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP HSJS1_k127_3799531_0 205922.Pfl01_3407 1.263e-185 592.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1YT09@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S type VI secretion protein evpB - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB HSJS1_k127_3799531_4 448385.sce9342 4.213e-41 158.0 COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,42UQR@68525|delta/epsilon subdivisions,2WQYW@28221|Deltaproteobacteria,2YV8B@29|Myxococcales 28221|Deltaproteobacteria S Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - ko:K11901 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VipA HSJS1_k127_3799531_1 1242864.D187_000575 1.365e-69 250.0 COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,42VE0@68525|delta/epsilon subdivisions,2WSAE@28221|Deltaproteobacteria,2YV27@29|Myxococcales 28221|Deltaproteobacteria S ImpA, N-terminal, type VI secretion system - - - ko:K11902 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - ImpA_N,T6SS_VasJ HSJS1_k127_3799531_2 1192034.CAP_6442 2.276e-67 258.0 COG3515@1|root,COG3523@1|root,COG3515@2|Bacteria,COG3523@2|Bacteria,1PMHX@1224|Proteobacteria,4346U@68525|delta/epsilon subdivisions,2X3C8@28221|Deltaproteobacteria,2YVD4@29|Myxococcales 28221|Deltaproteobacteria S ImcF-related N-terminal domain - - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - ImcF-related_N HSJS1_k127_3803656_0 378806.STAUR_4830 1.206e-143 470.0 COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2YUBN@29|Myxococcales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM HSJS1_k127_380909_1 290397.Adeh_0623 1.258e-148 475.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales 28221|Deltaproteobacteria NU twitching motility protein pilT-4 - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE HSJS1_k127_380909_2 903818.KI912268_gene3152 2.682e-137 448.0 COG1459@1|root,COG1459@2|Bacteria,3Y48Z@57723|Acidobacteria 57723|Acidobacteria NU Type II secretion system (T2SS), protein F - - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF HSJS1_k127_380909_3 1499967.BAYZ01000027_gene1787 1.132e-78 287.0 COG5000@1|root,COG5000@2|Bacteria,2NP6K@2323|unclassified Bacteria 2|Bacteria T His Kinase A (phosphoacceptor) domain pilS - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 HSJS1_k127_380909_0 269799.Gmet_1397 2.994e-150 492.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales 28221|Deltaproteobacteria T response regulator pilR - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_381112_3 1173029.JH980292_gene2347 4.458e-20 102.0 COG1232@1|root,COG3349@1|root,COG1232@2|Bacteria,COG3349@2|Bacteria,1G2DK@1117|Cyanobacteria 1117|Cyanobacteria H NAD(P)-binding Rossmann-like domain - - - - - - - - - - - - NAD_binding_8 HSJS1_k127_381112_1 1379270.AUXF01000002_gene1363 3.346e-109 386.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec HSJS1_k127_381112_0 240015.ACP_2612 1.87e-142 462.0 COG0045@1|root,COG0045@2|Bacteria,3Y36X@57723|Acidobacteria,2JHR1@204432|Acidobacteriia 204432|Acidobacteriia C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA HSJS1_k127_381112_2 335543.Sfum_1702 1.311e-20 101.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2MQUB@213462|Syntrophobacterales 28221|Deltaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,CoA_binding,Ligase_CoA HSJS1_k127_381141_0 309807.SRU_1701 4.242e-223 708.0 COG1960@1|root,COG3793@1|root,COG1960@2|Bacteria,COG3793@2|Bacteria,4NF87@976|Bacteroidetes,1FJZY@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes IP Acyl-CoA oxidase - - 1.3.3.6 ko:K00232 ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146 M00087,M00113 R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HSJS1_k127_381141_1 240015.ACP_2489 3.269e-182 612.0 28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria,2JMX9@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - HSJS1_k127_381141_2 1124780.ANNU01000066_gene378 1.104e-165 531.0 COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MXD@768503|Cytophagia 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH HSJS1_k127_381141_3 65393.PCC7424_4823 3.397e-102 337.0 COG0452@1|root,COG0452@2|Bacteria,1G2DG@1117|Cyanobacteria,3KG6V@43988|Cyanothece 1117|Cyanobacteria H TIGRFAM phosphopantothenoylcysteine decarboxylase phosphopantothenate cysteine ligase - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein HSJS1_k127_3815571_0 1242864.D187_006633 2.363e-19 103.0 COG2333@1|root,COG4733@1|root,COG4932@1|root,COG2333@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - 3.2.1.4 ko:K01179,ko:K02238,ko:K20276 ko00500,ko01100,ko02024,map00500,map01100,map02024 M00429 R06200,R11307,R11308 - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.11.1,3.A.11.2 GH5,GH9 - Lactamase_B HSJS1_k127_382001_4 649747.HMPREF0083_00832 2.089e-23 102.0 COG1073@1|root,COG1073@2|Bacteria,1V1RV@1239|Firmicutes,4HGDR@91061|Bacilli,26QPZ@186822|Paenibacillaceae 91061|Bacilli S Lysophospholipase M1-904 - - - - - - - - - - - Abhydrolase_1,DLH,Hydrolase_4 HSJS1_k127_382001_6 391625.PPSIR1_20349 9.669e-06 59.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CarboxypepD_reg,PDZ_2 HSJS1_k127_382001_3 1121013.P873_03340 1.028e-27 118.0 COG2373@1|root,COG2373@2|Bacteria,1NAB9@1224|Proteobacteria,1T1NJ@1236|Gammaproteobacteria,1X86W@135614|Xanthomonadales 135614|Xanthomonadales KLT Cytochrome oxidase complex assembly protein 1 - - - - - - - - - - - - Coa1 HSJS1_k127_382001_0 378806.STAUR_1528 2.228e-52 198.0 COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales 28221|Deltaproteobacteria E Glycine cleavage T-protein C-terminal barrel domain - - 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 - - - GCV_T,GCV_T_C HSJS1_k127_382001_2 404589.Anae109_3589 6.578e-36 140.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,431E6@68525|delta/epsilon subdivisions,2WWGA@28221|Deltaproteobacteria,2YVXB@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the HesB IscA family - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn HSJS1_k127_382001_1 886293.Sinac_3837 1.866e-45 181.0 COG0637@1|root,COG0637@2|Bacteria,2J0A7@203682|Planctomycetes 203682|Planctomycetes S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 HSJS1_k127_382001_5 667015.Bacsa_3106 7.324e-07 60.0 COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia,4AK73@815|Bacteroidaceae 976|Bacteroidetes F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK HSJS1_k127_382782_1 251229.Chro_3847 9.037e-97 324.0 COG3000@1|root,COG3000@2|Bacteria,1G7RK@1117|Cyanobacteria,3VKS3@52604|Pleurocapsales 1117|Cyanobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase HSJS1_k127_382782_0 1123508.JH636439_gene519 5.479e-123 409.0 COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes 203682|Planctomycetes S beta-propeller repeat - - - - - - - - - - - - PQQ_2 HSJS1_k127_3831845_2 649638.Trad_1823 1.541e-104 347.0 28HGI@1|root,2Z7SC@2|Bacteria,1WMFP@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - HSJS1_k127_3831845_1 1125863.JAFN01000001_gene2253 4.804e-131 433.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_3831845_5 321327.CYA_2272 8.285e-67 235.0 COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,1GZKF@1129|Synechococcus 1117|Cyanobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ HSJS1_k127_3831845_3 682795.AciX8_1037 5.395e-102 359.0 COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia 204432|Acidobacteriia G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV HSJS1_k127_3831845_9 563192.HMPREF0179_00900 2.717e-16 91.0 COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MC38@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM YbbR family protein - - - - - - - - - - - - YbbR HSJS1_k127_3831845_6 589865.DaAHT2_0445 9.508e-63 230.0 COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2MIQR@213118|Desulfobacterales 28221|Deltaproteobacteria S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N,YbbR HSJS1_k127_3831845_4 404589.Anae109_2337 2.369e-83 287.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind HSJS1_k127_3831845_0 1267535.KB906767_gene3168 3.515e-252 794.0 COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia 204432|Acidobacteriia O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 HSJS1_k127_3831845_7 555088.DealDRAFT_2465 4.107e-41 170.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42JX4@68298|Syntrophomonadaceae 186801|Clostridia D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C HSJS1_k127_3831845_8 1121472.AQWN01000004_gene793 1.791e-18 90.0 COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,24NEC@186801|Clostridia,262PB@186807|Peptococcaceae 186801|Clostridia K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 HSJS1_k127_3832500_1 926566.Terro_0752 1.403e-05 58.0 COG1629@1|root,COG1629@2|Bacteria,3Y2FQ@57723|Acidobacteria,2JIDJ@204432|Acidobacteriia 204432|Acidobacteriia P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarboxypepD_reg,Plug HSJS1_k127_3832500_0 1396141.BATP01000007_gene5788 1.246e-07 64.0 2DBSP@1|root,2ZAT9@2|Bacteria,46Z78@74201|Verrucomicrobia,2IWQF@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - HSJS1_k127_3833045_2 1254432.SCE1572_49405 9.812e-47 179.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2YVC1@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N HSJS1_k127_3833045_1 401053.AciPR4_0505 1.271e-108 364.0 COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia 204432|Acidobacteriia F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C HSJS1_k127_3833045_0 247490.KSU1_D0507 9.997e-199 644.0 COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes 203682|Planctomycetes Q Multicopper oxidase - - - - - - - - - - - - - HSJS1_k127_3836010_1 644966.Tmar_0500 2.202e-69 244.0 COG4637@1|root,COG4637@2|Bacteria,1VIP4@1239|Firmicutes,24SCT@186801|Clostridia 186801|Clostridia S PFAM SMC domain protein - - - - - - - - - - - - AAA_15,AAA_21 HSJS1_k127_3836010_2 502025.Hoch_2284 2.234e-37 164.0 COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,43AH9@68525|delta/epsilon subdivisions,2X5XB@28221|Deltaproteobacteria,2Z37F@29|Myxococcales 28221|Deltaproteobacteria P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Sulfatase HSJS1_k127_3836010_0 1232410.KI421413_gene842 9.691e-86 301.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans HSJS1_k127_3836010_3 266117.Rxyl_1353 0.0001682 46.0 COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria 201174|Actinobacteria E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 HSJS1_k127_3836090_13 1499967.BAYZ01000088_gene5097 1.378e-19 93.0 COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria 2|Bacteria M ABC-type transport system involved in lipoprotein release permease component lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 - - FtsX,MacB_PCD HSJS1_k127_3836090_7 243231.GSU2269 1.962e-70 251.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales 28221|Deltaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran HSJS1_k127_3836090_0 1382359.JIAL01000001_gene2740 7.291e-276 871.0 COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia 204432|Acidobacteriia O Belongs to the ClpA ClpB family - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N HSJS1_k127_3836090_4 1267535.KB906767_gene913 6.021e-79 293.0 COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria,2JHYD@204432|Acidobacteriia 204432|Acidobacteriia M TIGRFAM outer membrane protein assembly complex, YaeT protein - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA HSJS1_k127_3836090_15 768670.Calni_0301 7.622e-11 71.0 COG2825@1|root,COG2825@2|Bacteria,2GFRM@200930|Deferribacteres 200930|Deferribacteres M Outer membrane protein (OmpH-like) - - - ko:K06142 - - - - ko00000 - - - OmpH HSJS1_k127_3836090_3 1278073.MYSTI_05183 1.601e-79 279.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD HSJS1_k127_3836090_11 639030.JHVA01000001_gene2942 6.112e-50 187.0 COG0764@1|root,COG0764@2|Bacteria,3Y4CG@57723|Acidobacteria,2JJ97@204432|Acidobacteriia 204432|Acidobacteriia I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA HSJS1_k127_3836090_6 338963.Pcar_1255 1.985e-75 262.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria,43RXH@69541|Desulfuromonadales 28221|Deltaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep HSJS1_k127_3836090_8 1340493.JNIF01000003_gene3598 3.668e-69 263.0 COG0673@1|root,COG0673@2|Bacteria,3Y3ET@57723|Acidobacteria 57723|Acidobacteria S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA HSJS1_k127_3836090_2 671143.DAMO_1214 7.371e-110 362.0 COG0005@1|root,COG0005@2|Bacteria,2NNYQ@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates mtnP GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2684 PNP_UDP_1 HSJS1_k127_3836090_5 1278073.MYSTI_04936 3.166e-78 270.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2YVC8@29|Myxococcales 28221|Deltaproteobacteria F Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE HSJS1_k127_3836090_10 880072.Desac_1175 1.591e-60 227.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales 28221|Deltaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT HSJS1_k127_3836090_12 585394.RHOM_07150 1.688e-22 113.0 COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - ko:K08974 - - - - ko00000 - - - DUF368 HSJS1_k127_3836090_14 485915.Dret_1283 4.921e-16 81.0 COG1254@1|root,COG1254@2|Bacteria,1QUKD@1224|Proteobacteria,42XEI@68525|delta/epsilon subdivisions,2WTAI@28221|Deltaproteobacteria,2MD53@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM acylphosphatase acyP - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase HSJS1_k127_3836090_9 639030.JHVA01000001_gene3325 5.507e-63 220.0 COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria,2JHP2@204432|Acidobacteriia 204432|Acidobacteriia F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran HSJS1_k127_3836090_1 1144275.COCOR_01877 3.9e-185 599.0 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WKMQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage tail sheath protein - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C HSJS1_k127_3859390_1 1121104.AQXH01000002_gene673 9.792e-30 123.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IPQT@117747|Sphingobacteriia 976|Bacteroidetes I PFAM AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding HSJS1_k127_3859390_0 1232410.KI421415_gene3026 4.878e-165 543.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2X28Y@28221|Deltaproteobacteria,43U5A@69541|Desulfuromonadales 28221|Deltaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - 3HCDH,3HCDH_N,ECH_1 HSJS1_k127_3863464_2 880073.Calab_1414 8.032e-36 141.0 COG0388@1|root,COG0388@2|Bacteria,2NPKU@2323|unclassified Bacteria 2|Bacteria S Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase HSJS1_k127_3863464_0 211165.AJLN01000100_gene4246 6.352e-208 670.0 COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae 1117|Cyanobacteria S Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8 HSJS1_k127_3863464_1 1217720.ALOX01000079_gene3239 2.507e-94 326.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - - - - - - - - - - SIR2 HSJS1_k127_3863464_3 1122915.AUGY01000079_gene3338 1.291e-34 145.0 COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,4HTDM@91061|Bacilli,26S52@186822|Paenibacillaceae 91061|Bacilli P Sulfatase - - - - - - - - - - - - Sulfatase HSJS1_k127_3867822_1 1198114.AciX9_2492 3.979e-22 115.0 COG4932@1|root,COG4932@2|Bacteria,3Y8E2@57723|Acidobacteria 57723|Acidobacteria M Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg HSJS1_k127_3867822_2 641112.ACOK01000001_gene3542 2.221e-14 89.0 COG1800@1|root,COG1800@2|Bacteria,1W0TW@1239|Firmicutes,25ESS@186801|Clostridia 186801|Clostridia O Belongs to the peptidase S8 family - - - - - - - - - - - - - HSJS1_k127_3867822_0 1249975.JQLP01000003_gene76 1.258e-101 378.0 COG1361@1|root,COG3266@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1HZAG@117743|Flavobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,DUF11 HSJS1_k127_3875653_1 1454004.AW11_03331 7.296e-146 481.0 COG1226@1|root,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria 1224|Proteobacteria P Ion transport 2 domain protein - - - - - - - - - - - - Ion_trans_2,TrkA_C,TrkA_N HSJS1_k127_3875653_6 330214.NIDE4157 2.026e-30 125.0 COG3824@1|root,COG3824@2|Bacteria 2|Bacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_1 HSJS1_k127_3875653_5 215803.DB30_7450 6.981e-38 159.0 COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,438TC@68525|delta/epsilon subdivisions,2X45R@28221|Deltaproteobacteria,2YXQM@29|Myxococcales 28221|Deltaproteobacteria GM NmrA-like family - - - - - - - - - - - - Epimerase HSJS1_k127_3875653_12 1278073.MYSTI_03705 7.613e-20 97.0 COG2823@1|root,COG5637@1|root,COG2823@2|Bacteria,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,437A8@68525|delta/epsilon subdivisions,2X2EK@28221|Deltaproteobacteria,2YVIY@29|Myxococcales 28221|Deltaproteobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc HSJS1_k127_3875653_2 502025.Hoch_2064 5.378e-131 430.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,42PQ6@68525|delta/epsilon subdivisions,2WJHR@28221|Deltaproteobacteria,2YV9V@29|Myxococcales 28221|Deltaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH HSJS1_k127_3875653_10 338966.Ppro_2030 9.725e-22 111.0 COG1846@1|root,COG1846@2|Bacteria,1NRG9@1224|Proteobacteria,42YC6@68525|delta/epsilon subdivisions,2WTKJ@28221|Deltaproteobacteria,43TP5@69541|Desulfuromonadales 28221|Deltaproteobacteria K Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388 HSJS1_k127_3875653_8 338963.Pcar_1410 2.599e-23 112.0 COG2203@1|root,COG2203@2|Bacteria,1RJ35@1224|Proteobacteria,42T0K@68525|delta/epsilon subdivisions,2WPIM@28221|Deltaproteobacteria,43T60@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - - HSJS1_k127_3875653_7 316067.Geob_3387 3.625e-29 128.0 COG0745@1|root,COG0745@2|Bacteria,1R9AR@1224|Proteobacteria,42YHD@68525|delta/epsilon subdivisions,2WU58@28221|Deltaproteobacteria 28221|Deltaproteobacteria T cheY-homologous receiver domain - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg HSJS1_k127_3875653_11 502025.Hoch_5363 6.776e-21 95.0 COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions,2WQGU@28221|Deltaproteobacteria,2YVQK@29|Myxococcales 28221|Deltaproteobacteria C Ferredoxin - - - - - - - - - - - - - HSJS1_k127_3875653_13 1125863.JAFN01000001_gene3090 9.196e-15 79.0 COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria 28221|Deltaproteobacteria T RNA polymerase-binding protein DksA dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR HSJS1_k127_3875653_3 1128421.JAGA01000002_gene1138 3.113e-83 288.0 COG0119@1|root,COG0119@2|Bacteria 2|Bacteria E Belongs to the alpha-IPM synthase homocitrate synthase family mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like HSJS1_k127_3875653_9 1046724.KB889881_gene1783 2.884e-23 109.0 COG0346@1|root,COG0346@2|Bacteria,1NBWY@1224|Proteobacteria,1SCXS@1236|Gammaproteobacteria,46C3B@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 HSJS1_k127_3875653_4 266117.Rxyl_2747 6.903e-71 246.0 COG1335@1|root,COG1335@2|Bacteria 2|Bacteria Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - 3.5.1.107 ko:K13995 ko00760,ko01120,map00760,map01120 M00622 R03540 RC00950 ko00000,ko00001,ko00002,ko01000 - - - Isochorismatase HSJS1_k127_3875653_0 1122194.AUHU01000004_gene1633 1.14e-175 558.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,464AG@72275|Alteromonadaceae 1236|Gammaproteobacteria C CoA-transferase family III frc - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 HSJS1_k127_38795_1 644966.Tmar_1637 4.642e-45 173.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,24H71@186801|Clostridia 186801|Clostridia C PFAM FAD dependent oxidoreductase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C HSJS1_k127_38795_0 66897.DJ64_34180 2.796e-49 183.0 COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria 201174|Actinobacteria C FAD linked eapA - 2.5.1.26 ko:K00803 ko00565,ko01100,ko04146,map00565,map01100,map04146 - R04311 RC00020,RC02886 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 HSJS1_k127_3881200_4 1131269.AQVV01000008_gene963 1.939e-07 60.0 COG1108@1|root,COG1108@2|Bacteria 2|Bacteria P ABC-type Mn2 Zn2 transport systems permease components znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 HSJS1_k127_3881200_1 880073.Calab_1818 5.497e-99 347.0 COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria 2|Bacteria P Belongs to the bacterial solute-binding protein 9 family znuA - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA HSJS1_k127_3881200_2 880073.Calab_1819 1.36e-56 216.0 COG3170@1|root,COG3170@2|Bacteria,2NPXD@2323|unclassified Bacteria 2|Bacteria NU Tfp pilus assembly protein FimV - - 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - DUF4157,Pkinase HSJS1_k127_3881200_3 760192.Halhy_4054 2.249e-55 202.0 COG4845@1|root,COG4845@2|Bacteria,4NPDG@976|Bacteroidetes,1IS3J@117747|Sphingobacteriia 976|Bacteroidetes V Chloramphenicol acetyltransferase cat - 2.3.1.28 ko:K19271 - - - - br01600,ko00000,ko01000,ko01504 - - - CAT HSJS1_k127_3881200_0 391625.PPSIR1_35712 1.481e-265 835.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria 28221|Deltaproteobacteria G K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - Sortilin-Vps10 HSJS1_k127_3883880_19 1238182.C882_0599 6.934e-06 53.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria,2JPVU@204441|Rhodospirillales 204441|Rhodospirillales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C HSJS1_k127_3883880_11 246194.CHY_2293 2.233e-37 152.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,42GIE@68295|Thermoanaerobacterales 186801|Clostridia J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p HSJS1_k127_3883880_5 671143.DAMO_0554 4.937e-56 201.0 COG0097@1|root,COG0097@2|Bacteria,2NPAS@2323|unclassified Bacteria 2|Bacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 HSJS1_k127_3883880_9 665571.STHERM_c05100 4.066e-43 162.0 COG0096@1|root,COG0096@2|Bacteria,2J7SM@203691|Spirochaetes 203691|Spirochaetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 HSJS1_k127_3883880_17 1340493.JNIF01000003_gene3220 3.84e-19 92.0 COG0199@1|root,COG0199@2|Bacteria,3Y5HM@57723|Acidobacteria 57723|Acidobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 HSJS1_k127_3883880_2 1123371.ATXH01000034_gene783 1.94e-71 248.0 COG0094@1|root,COG0094@2|Bacteria,2GHJW@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C HSJS1_k127_3883880_12 717605.Theco_0292 1.153e-32 131.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,26XQC@186822|Paenibacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 HSJS1_k127_3883880_6 240015.ACP_1441 4.697e-52 186.0 COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia 204432|Acidobacteriia J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN - - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 HSJS1_k127_3883880_15 309803.CTN_1002 8.683e-23 105.0 COG0186@1|root,COG0186@2|Bacteria,2GD97@200918|Thermotogae 200918|Thermotogae J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 HSJS1_k127_3883880_18 123214.PERMA_1204 1.082e-11 68.0 COG0255@1|root,COG0255@2|Bacteria,2G4E0@200783|Aquificae 200783|Aquificae J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 HSJS1_k127_3883880_4 880073.Calab_2133 3.952e-60 212.0 COG0197@1|root,COG0197@2|Bacteria,2NPC6@2323|unclassified Bacteria 2|Bacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 HSJS1_k127_3883880_1 1267535.KB906767_gene2698 4.701e-84 284.0 COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria,2JIRU@204432|Acidobacteriia 204432|Acidobacteriia J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C HSJS1_k127_3883880_13 1168067.JAGP01000001_gene261 3.535e-26 111.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales 72273|Thiotrichales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 HSJS1_k127_3883880_10 768670.Calni_1503 1.686e-37 143.0 COG0185@1|root,COG0185@2|Bacteria,2GFND@200930|Deferribacteres 200930|Deferribacteres J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS - - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 HSJS1_k127_3883880_0 1121405.dsmv_3586 6.3e-119 392.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2MIFY@213118|Desulfobacterales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C HSJS1_k127_3883880_14 644282.Deba_2936 3.663e-23 114.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria 28221|Deltaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 HSJS1_k127_3883880_7 1274524.BSONL12_21994 6.832e-49 181.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,1ZBG9@1386|Bacillus 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 HSJS1_k127_3883880_3 742722.HMPREF9463_00925 5.623e-70 242.0 COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CUQE@84998|Coriobacteriia 84998|Coriobacteriia J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 HSJS1_k127_3883880_8 1340493.JNIF01000003_gene3206 8.237e-47 170.0 COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria 57723|Acidobacteria J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 HSJS1_k127_3883880_16 1000565.METUNv1_02248 9.177e-23 97.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,2KVV4@206389|Rhodocyclales 206389|Rhodocyclales J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 HSJS1_k127_3885828_3 1266925.JHVX01000011_gene1488 1.533e-65 232.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,372MM@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM HSJS1_k127_3885828_8 290397.Adeh_2514 4.387e-33 133.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2Z24M@29|Myxococcales 28221|Deltaproteobacteria H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS HSJS1_k127_3885828_9 1121472.AQWN01000004_gene659 5.586e-11 67.0 COG4636@1|root,COG4636@2|Bacteria,1VEA1@1239|Firmicutes,250SS@186801|Clostridia,265AQ@186807|Peptococcaceae 186801|Clostridia S Putative restriction endonuclease - - - - - - - - - - - - Uma2 HSJS1_k127_3885828_0 1232410.KI421415_gene2975 1.301e-181 582.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales 28221|Deltaproteobacteria HJ RimK-like ATPgrasp N-terminal domain - - - - - - - - - - - - Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK HSJS1_k127_3885828_1 1232410.KI421415_gene2974 4.082e-135 448.0 COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales 28221|Deltaproteobacteria S Glutamate-cysteine ligase family 2(GCS2) - - - - - - - - - - - - GCS2 HSJS1_k127_3885828_4 502025.Hoch_5424 1.152e-45 177.0 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,43513@68525|delta/epsilon subdivisions,2X944@28221|Deltaproteobacteria,2Z1T3@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function (DUF1223) - - - - - - - - - - - - DUF1223 HSJS1_k127_3885828_5 443144.GM21_1290 1.351e-44 175.0 COG3012@1|root,COG3012@2|Bacteria,1NV40@1224|Proteobacteria 1224|Proteobacteria S SEC-C Motif Domain Protein - - - - - - - - - - - - DUF2384,SEC-C HSJS1_k127_3885828_10 1304880.JAGB01000002_gene1579 2.383e-06 59.0 COG3012@1|root,COG3012@2|Bacteria 2|Bacteria - - - - - ko:K07039,ko:K09858 - - - - ko00000 - - - PRiA4_ORF3,SEC-C HSJS1_k127_3885828_6 1122179.KB890417_gene3237 1.026e-35 151.0 COG3710@1|root,COG3710@2|Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - Trans_reg_C HSJS1_k127_3885828_2 1122179.KB890417_gene3238 2.157e-118 397.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus - - - ko:K06867 - - - - ko00000 - - - Ank,Ank_2,Ank_4,Ank_5 HSJS1_k127_3885828_7 661478.OP10G_4489 1.712e-33 137.0 2A52F@1|root,30TQU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_3888268_1 247490.KSU1_B0203 1.606e-25 121.0 2EE39@1|root,337XU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_3888268_0 626887.J057_13596 1.514e-150 488.0 COG4399@1|root,COG4399@2|Bacteria,1R42C@1224|Proteobacteria,1RPWG@1236|Gammaproteobacteria,469GI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - - HSJS1_k127_3888268_2 195250.CM001776_gene339 6.972e-22 106.0 COG5611@1|root,COG5611@2|Bacteria,1G6XT@1117|Cyanobacteria 1117|Cyanobacteria S nucleic-acid-binding protein contains PIN domain - - - - - - - - - - - - PIN HSJS1_k127_3888268_3 63737.Npun_F4599 5.451e-14 74.0 COG2002@1|root,COG2002@2|Bacteria,1G8HV@1117|Cyanobacteria,1HPB3@1161|Nostocales 1117|Cyanobacteria K TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - - - - - - - - - - MazE_antitoxin,PrlF_antitoxin HSJS1_k127_3888268_4 395964.KE386496_gene580 1.08e-12 71.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,3NAFR@45404|Beijerinckiaceae 28211|Alphaproteobacteria M MacB-like periplasmic core domain lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD HSJS1_k127_3890434_0 1297863.APJF01000008_gene636 1.447e-130 434.0 COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,3JSXW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Cleaves the N-terminal amino acid of tripeptides pepT - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 HSJS1_k127_3893936_1 1210884.HG799469_gene14163 2.099e-142 477.0 COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes 203682|Planctomycetes S beta-propeller repeat - - - - - - - - - - - - PQQ_2,PQQ_3 HSJS1_k127_3893936_5 1487921.DP68_13115 2.563e-05 57.0 COG3012@1|root,COG3012@2|Bacteria,1V9F3@1239|Firmicutes,24MI8@186801|Clostridia,36RXR@31979|Clostridiaceae 186801|Clostridia S SEC-C motif - - - - - - - - - - - - SEC-C HSJS1_k127_3893936_0 518766.Rmar_0345 2.914e-194 625.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes 976|Bacteroidetes S TIGRFAM amidohydrolase - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 HSJS1_k127_3893936_4 713586.KB900536_gene1206 4.946e-08 55.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - - - - - - - - - - - MerC,Methyltransf_31 HSJS1_k127_3893936_2 713586.KB900536_gene1206 9.979e-70 243.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - - - - - - - - - - - MerC,Methyltransf_31 HSJS1_k127_3893936_3 195253.Syn6312_1425 2.443e-32 134.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H3W9@1129|Synechococcus 1117|Cyanobacteria S R COG0457 FOG TPR repeat - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_7,TPR_8 HSJS1_k127_3915242_2 748247.AZKH_4256 1.558e-32 127.0 COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2VIIC@28216|Betaproteobacteria,2KY5V@206389|Rhodocyclales 206389|Rhodocyclales C cytochrome C peroxidase - - - - - - - - - - - - - HSJS1_k127_3915242_0 85643.Tmz1t_2184 1.957e-298 936.0 COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,2VJWF@28216|Betaproteobacteria,2KY3E@206389|Rhodocyclales 206389|Rhodocyclales C Cytochrome c - - - - - - - - - - - - - HSJS1_k127_3915242_1 1123392.AQWL01000003_gene254 4.137e-80 290.0 29FX8@1|root,302UX@2|Bacteria,1P7W7@1224|Proteobacteria,2VM6V@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3915242_3 159087.Daro_2938 1.158e-05 53.0 28MTI@1|root,2ZB1Q@2|Bacteria,1R894@1224|Proteobacteria,2VMZB@28216|Betaproteobacteria,2KVD1@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - HSJS1_k127_391662_1 493475.GARC_3174 2.31e-33 138.0 COG3832@1|root,COG3832@2|Bacteria,1NJ23@1224|Proteobacteria,1SJB2@1236|Gammaproteobacteria,46C5V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 HSJS1_k127_391662_2 1173027.Mic7113_3655 3.713e-28 116.0 COG0640@1|root,COG0640@2|Bacteria,1G6T4@1117|Cyanobacteria 1117|Cyanobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 HSJS1_k127_391662_0 1254432.SCE1572_30705 9.141e-112 384.0 COG1193@1|root,COG1193@2|Bacteria 2|Bacteria L negative regulation of DNA recombination mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr HSJS1_k127_3917893_0 1499967.BAYZ01000103_gene3780 9.877e-27 128.0 COG0457@1|root,COG0457@2|Bacteria 1499967.BAYZ01000103_gene3780|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_3917893_1 886293.Sinac_5391 1.559e-16 95.0 COG1216@1|root,COG1216@2|Bacteria,2IZMW@203682|Planctomycetes 203682|Planctomycetes S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_3919507_1 1183438.GKIL_3356 5.333e-85 298.0 COG2866@1|root,COG2866@2|Bacteria 2|Bacteria E metallocarboxypeptidase activity - - - - - - - - - - - - Peptidase_M14 HSJS1_k127_3919507_2 348780.NP_4210A 1.938e-71 256.0 COG1804@1|root,arCOG02304@2157|Archaea,2XTNU@28890|Euryarchaeota,23TB7@183963|Halobacteria 183963|Halobacteria C L-carnitine dehydratase bile acid-inducible protein F - - - - - - - - - - - - CoA_transf_3 HSJS1_k127_3919507_3 497964.CfE428DRAFT_4946 6.466e-47 177.0 2EK8J@1|root,33DYX@2|Bacteria,46VTQ@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - HSJS1_k127_3919507_0 1122919.KB905557_gene1201 3.827e-118 391.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,26QTH@186822|Paenibacillaceae 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt HSJS1_k127_3928877_0 234267.Acid_2174 4.729e-41 163.0 COG2133@1|root,COG2133@2|Bacteria 2|Bacteria G pyrroloquinoline quinone binding - - - - - - - - - - - - CHRD,Calx-beta,F5_F8_type_C,PA14,RicinB_lectin_2,Ricin_B_lectin,SdrD_B HSJS1_k127_3928877_1 391603.FBALC1_07508 4.273e-39 156.0 COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NUCQ@976|Bacteroidetes 976|Bacteroidetes C ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_3928877_2 1296415.JACC01000002_gene3187 6.787e-06 57.0 COG2931@1|root,COG3227@1|root,COG3509@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3509@2|Bacteria,4NX38@976|Bacteroidetes,1IKNH@117743|Flavobacteriia,2YGKC@290174|Aquimarina 2|Bacteria EQ Trypsin-like serine protease - - - ko:K03932 - - - - ko00000 - CE1 - Esterase_phd HSJS1_k127_3936613_1 1217720.ALOX01000010_gene1990 1.292e-65 239.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2JPGN@204441|Rhodospirillales 204441|Rhodospirillales S MazG nucleotide pyrophosphohydrolase domain mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG HSJS1_k127_3936613_0 1183438.GKIL_4354 8.107e-145 488.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_3936613_2 518766.Rmar_0571 4.774e-13 78.0 COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria,4NEE5@976|Bacteroidetes,1FIQ3@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO HSJS1_k127_394074_3 1125863.JAFN01000001_gene1632 8.732e-26 110.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42Z38@68525|delta/epsilon subdivisions,2X5H0@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 HSJS1_k127_394074_1 234267.Acid_5898 2.755e-85 298.0 COG0665@1|root,COG0665@2|Bacteria,3Y6FQ@57723|Acidobacteria 57723|Acidobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO HSJS1_k127_394074_0 1121104.AQXH01000002_gene637 1.539e-105 353.0 COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia 976|Bacteroidetes E Cystathionine beta-synthase - - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP HSJS1_k127_394074_2 1304275.C41B8_02692 5.492e-45 171.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 AIRC HSJS1_k127_3943874_1 215803.DB30_7168 1.185e-28 126.0 COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales 28221|Deltaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding HSJS1_k127_3943874_0 1121448.DGI_1586 3.244e-58 216.0 COG1219@1|root,COG1219@2|Bacteria,1NS53@1224|Proteobacteria,42YDC@68525|delta/epsilon subdivisions,2WU6T@28221|Deltaproteobacteria,2MAA0@213115|Desulfovibrionales 28221|Deltaproteobacteria O AAA domain (Cdc48 subfamily) - - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2 HSJS1_k127_3949753_1 1089550.ATTH01000001_gene1715 7.794e-141 483.0 COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1FJEM@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S ABC1 family - - - ko:K03688 - - - - ko00000 - - - ABC1 HSJS1_k127_3949753_0 926550.CLDAP_00280 1.299e-219 694.0 COG1257@1|root,COG1257@2|Bacteria 2|Bacteria I hydroxymethylglutaryl-CoA reductase (NADPH) activity hmgA - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red HSJS1_k127_3956718_1 887062.HGR_10520 1.342e-114 386.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,4ABG0@80864|Comamonadaceae 28216|Betaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 HSJS1_k127_3956718_0 1125863.JAFN01000001_gene893 4.349e-136 458.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria 28221|Deltaproteobacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.1.202,2.7.3.9 ko:K02768,ko:K08483,ko:K11183 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 - - EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr HSJS1_k127_3956718_15 1125863.JAFN01000001_gene894 2.524e-21 104.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,42V5C@68525|delta/epsilon subdivisions,2WRC4@28221|Deltaproteobacteria 28221|Deltaproteobacteria G TIGRFAM phosphocarrier, HPr family ptsH - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr HSJS1_k127_3956718_14 290397.Adeh_0148 1.563e-21 106.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria 28221|Deltaproteobacteria G PFAM PTS system fructose subfamily IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man HSJS1_k127_3956718_8 404589.Anae109_0152 1.305e-72 259.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2YV1E@29|Myxococcales 28221|Deltaproteobacteria S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 HSJS1_k127_3956718_6 290397.Adeh_0146 2.102e-88 302.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N HSJS1_k127_3956718_13 1242864.D187_002011 4.589e-27 116.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2YVHR@29|Myxococcales 28221|Deltaproteobacteria G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 HSJS1_k127_3956718_12 443144.GM21_3389 7.646e-29 130.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,43TY8@69541|Desulfuromonadales 28221|Deltaproteobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE HSJS1_k127_3956718_3 338963.Pcar_1938 9.34e-108 369.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales 28221|Deltaproteobacteria K Sigma-54 factor, Activator interacting domain (AID) rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD HSJS1_k127_3956718_5 1340493.JNIF01000003_gene2837 2.736e-94 320.0 COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria 57723|Acidobacteria S PFAM ABC transporter - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C HSJS1_k127_3956718_4 997346.HMPREF9374_0209 3.614e-105 367.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,27B5P@186824|Thermoactinomycetaceae 91061|Bacilli L Single-strand DNA-specific exonuclease, C terminal domain recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C HSJS1_k127_3956718_2 269799.Gmet_1216 6.152e-114 376.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,43UDE@69541|Desulfuromonadales 28221|Deltaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA HSJS1_k127_3956718_9 316274.Haur_4101 1.041e-53 204.0 COG5530@1|root,COG5530@2|Bacteria 2|Bacteria S Predicted integral membrane protein (DUF2270) - - - - - - - - - - - - DUF2270 HSJS1_k127_3956718_16 1120973.AQXL01000134_gene1564 7.93e-16 90.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,279CV@186823|Alicyclobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179,YitT_membrane HSJS1_k127_3956718_10 1313304.CALK_1690 7.491e-38 164.0 COG1033@1|root,COG1033@2|Bacteria 2|Bacteria S growth of symbiont in host cell mmpL2 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - ko:K06994,ko:K07003 - - - - ko00000 - - - MMPL HSJS1_k127_3956718_7 1382359.JIAL01000001_gene1740 2.14e-77 280.0 COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria,2JP3Y@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein FAD-binding domain - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha HSJS1_k127_3956718_11 1265505.ATUG01000001_gene3637 1.207e-32 133.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42PYM@68525|delta/epsilon subdivisions,2WJ37@28221|Deltaproteobacteria,2MIP8@213118|Desulfobacterales 28221|Deltaproteobacteria C Electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF HSJS1_k127_3960864_0 502025.Hoch_3323 8.577e-173 563.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,42YBA@68525|delta/epsilon subdivisions,2WUP5@28221|Deltaproteobacteria,2YX31@29|Myxococcales 28221|Deltaproteobacteria S Peptidase, M61 - - - - - - - - - - - - PDZ_2,Peptidase_M61 HSJS1_k127_3960864_1 1125863.JAFN01000001_gene2072 1.533e-46 171.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria 28221|Deltaproteobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase HSJS1_k127_3960864_2 265072.Mfla_2424 3.479e-43 164.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,2KMPH@206350|Nitrosomonadales 206350|Nitrosomonadales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB HSJS1_k127_396162_1 502025.Hoch_4681 3.066e-44 169.0 COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,43B8H@68525|delta/epsilon subdivisions,2X6MV@28221|Deltaproteobacteria,2Z3BS@29|Myxococcales 28221|Deltaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu HSJS1_k127_396162_0 309807.SRU_2467 2.623e-79 282.0 COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - HSJS1_k127_396162_2 477184.KYC_23183 4.104e-09 68.0 COG1437@1|root,COG1437@2|Bacteria,1RJYE@1224|Proteobacteria,2VT6N@28216|Betaproteobacteria,3T7NJ@506|Alcaligenaceae 28216|Betaproteobacteria F Adenylate cyclase - - - - - - - - - - - - CYTH HSJS1_k127_3962176_1 1125863.JAFN01000001_gene515 5.198e-17 91.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2X708@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Penicillin-binding protein 1A - - 2.4.1.129,3.4.16.4 ko:K05366,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase HSJS1_k127_3962176_3 452637.Oter_3373 1.971e-10 70.0 COG1520@1|root,COG4585@1|root,COG1520@2|Bacteria,COG4585@2|Bacteria,46V08@74201|Verrucomicrobia,3K8KR@414999|Opitutae 2|Bacteria T histidine kinase dimerisation and phosphoacceptor region - - 3.5.1.56 ko:K03418 ko00630,map00630 - R02509 RC00111,RC00731 ko00000,ko00001,ko01000 - - - HATPase_c,HisKA_3,PQQ_2 HSJS1_k127_3962176_2 443143.GM18_1027 1.077e-10 73.0 COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42SJA@68525|delta/epsilon subdivisions,2WPP4@28221|Deltaproteobacteria,43VIA@69541|Desulfuromonadales 28221|Deltaproteobacteria T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8,PAS_9,Response_reg HSJS1_k127_3962176_4 393595.ABO_2080 6.54e-10 62.0 28M46@1|root,2ZAI5@2|Bacteria,1R68K@1224|Proteobacteria,1SB6S@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3962176_0 518766.Rmar_2078 3.315e-76 261.0 COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1FJTN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P Sodium:sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp HSJS1_k127_3964527_5 1242864.D187_009330 1.271e-17 89.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - - - - - - - - - - - - HSJS1_k127_3964527_2 247633.GP2143_09320 2.638e-40 167.0 COG0624@1|root,COG0624@2|Bacteria,1R40H@1224|Proteobacteria,1SMXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Peptidase family M20/M25/M40 - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 HSJS1_k127_3964527_4 1047013.AQSP01000115_gene360 3.495e-19 94.0 COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl HSJS1_k127_3964527_0 314285.KT71_04350 1.379e-81 290.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 HSJS1_k127_3964527_6 1499967.BAYZ01000075_gene2072 1.301e-11 73.0 COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif pulG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG HSJS1_k127_3964527_3 309801.trd_1801 2.41e-23 117.0 COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia 189775|Thermomicrobia S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO HSJS1_k127_3964527_1 56780.SYN_00575 1.237e-56 206.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,2MQEJ@213462|Syntrophobacterales 28221|Deltaproteobacteria M Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 HSJS1_k127_397294_0 1267534.KB906754_gene2914 0.0001041 53.0 COG0457@1|root,COG0457@2|Bacteria 1267534.KB906754_gene2914|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_3978255_1 1267533.KB906738_gene2305 3.24e-12 71.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB HSJS1_k127_3978255_2 391625.PPSIR1_08012 3.281e-07 64.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - - HSJS1_k127_3978255_0 1449347.JQLN01000004_gene6453 2.349e-177 589.0 COG2132@1|root,COG2132@2|Bacteria,2IDP7@201174|Actinobacteria 201174|Actinobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_3 HSJS1_k127_3982778_3 290397.Adeh_1821 8.316e-32 129.0 COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WNRX@28221|Deltaproteobacteria,2Z30D@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB HSJS1_k127_3982778_1 861299.J421_4262 9.587e-80 277.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA HSJS1_k127_3982778_4 755178.Cyan10605_2040 6.871e-19 88.0 2E90H@1|root,3339X@2|Bacteria,1G9EW@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_3982778_5 706587.Desti_5217 2.428e-18 85.0 2C1SS@1|root,32YN6@2|Bacteria,1NNFV@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_3982778_0 1210884.HG799464_gene10754 5.614e-88 299.0 COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes 203682|Planctomycetes NOU Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox HSJS1_k127_3982778_2 1267535.KB906767_gene5244 5.946e-50 189.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase HSJS1_k127_3984515_1 344747.PM8797T_28839 2.135e-67 238.0 COG0224@1|root,COG0224@2|Bacteria,2IXDI@203682|Planctomycetes 203682|Planctomycetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt HSJS1_k127_3984515_0 521674.Plim_0176 3.846e-221 694.0 COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes 203682|Planctomycetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N HSJS1_k127_3984515_2 756499.Desde_4102 5.375e-15 83.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,2629N@186807|Peptococcaceae 186801|Clostridia C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iHN637.CLJU_RS01195 ATP-synt_DE,ATP-synt_DE_N HSJS1_k127_39846_1 1123242.JH636435_gene2917 1.895e-35 153.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes 203682|Planctomycetes P arylsulfatase A - - - - - - - - - - - - Sulfatase,TPR_16,TPR_19,TPR_2 HSJS1_k127_39846_0 1121930.AQXG01000011_gene1759 2.434e-112 367.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes 976|Bacteroidetes E Peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - DPPIV_N,Peptidase_S9 HSJS1_k127_3984613_1 63737.Npun_F2730 2.008e-12 76.0 COG3055@1|root,COG3055@2|Bacteria,1G2B7@1117|Cyanobacteria,1HJHZ@1161|Nostocales 1117|Cyanobacteria S Domain of unknown function (DUF1929) - - - - - - - - - - - - DUF1929 HSJS1_k127_3984613_0 1122239.AULS01000001_gene2066 1.005e-31 128.0 COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4FS1J@85023|Microbacteriaceae 201174|Actinobacteria S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep HSJS1_k127_3991467_0 1385517.N800_09900 1.348e-94 323.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XDAY@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_3991467_1 379066.GAU_0378 2.801e-25 121.0 COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes 142182|Gemmatimonadetes U ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 HSJS1_k127_4007190_0 472759.Nhal_2074 9.885e-200 640.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,1X213@135613|Chromatiales 135613|Chromatiales C Acetyl-CoA hydrolase/transferase C-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro HSJS1_k127_4007190_2 1123053.AUDG01000001_gene2384 1.768e-20 93.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria,1X1RW@135613|Chromatiales 135613|Chromatiales S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc HSJS1_k127_4007190_1 1184267.A11Q_1872 8.557e-48 175.0 COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,42P0E@68525|delta/epsilon subdivisions,2MTS0@213481|Bdellovibrionales,2WISM@28221|Deltaproteobacteria 213481|Bdellovibrionales M mechanosensitive ion channel - - - ko:K16053 - - - - ko00000,ko02000 1.A.23.4.5 - - MS_channel HSJS1_k127_4008841_0 1089550.ATTH01000001_gene1831 6.877e-153 519.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_4008841_1 234267.Acid_7677 4.978e-48 186.0 COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria 57723|Acidobacteria K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_4010587_0 518766.Rmar_0337 1.168e-177 573.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1FIWT@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Pyruvate:ferredoxin oxidoreductase core domain II porA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N HSJS1_k127_4010587_1 479431.Namu_5377 3.969e-86 290.0 COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4ERDE@85013|Frankiales 201174|Actinobacteria C PFAM Thiamine pyrophosphate korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C HSJS1_k127_4014232_0 1128427.KB904821_gene174 1.631e-72 254.0 COG0705@1|root,COG0705@2|Bacteria,1G5IY@1117|Cyanobacteria,1HF1W@1150|Oscillatoriales 1117|Cyanobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid HSJS1_k127_4014232_2 502025.Hoch_2113 1.331e-28 121.0 COG1327@1|root,COG1327@2|Bacteria 502025.Hoch_2113|- K negative regulation of transcription, DNA-templated - - - - - - - - - - - - - HSJS1_k127_4014232_1 1267535.KB906767_gene5244 1.188e-34 152.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase HSJS1_k127_4014232_3 1336243.JAEA01000020_gene1588 5.38e-21 94.0 COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VG84@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NAD(P)H-dependent FMN reductase - - - - - - - - - - - - FMN_red HSJS1_k127_401791_3 1123371.ATXH01000022_gene990 6.248e-17 82.0 COG3654@1|root,COG3654@2|Bacteria 2|Bacteria - - doc - - ko:K07341 - - - - ko00000,ko02048 - - - Fic HSJS1_k127_401791_1 1499967.BAYZ01000139_gene160 1.308e-54 197.0 COG4636@1|root,COG4636@2|Bacteria 2|Bacteria D protein conserved in cyanobacteria - - - - - - - - - - - - Uma2 HSJS1_k127_401791_0 391625.PPSIR1_00802 1.243e-187 601.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF-2 - 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB HSJS1_k127_401791_2 861299.J421_0283 4.735e-53 205.0 COG0577@1|root,COG0577@2|Bacteria 861299.J421_0283|- V efflux transmembrane transporter activity - - - - - - - - - - - - - HSJS1_k127_4018669_0 290317.Cpha266_0557 1.224e-22 109.0 COG3074@1|root,COG3074@2|Bacteria,1FFHR@1090|Chlorobi 1090|Chlorobi D FtsZ-dependent cytokinesis - - - - - - - - - - - - - HSJS1_k127_4027095_1 234267.Acid_0372 6.571e-149 489.0 COG3104@1|root,COG3104@2|Bacteria,3Y6W5@57723|Acidobacteria 57723|Acidobacteria E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 HSJS1_k127_4027095_0 1047013.AQSP01000134_gene1354 9.997e-189 600.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process - - - - - - - - - - - - Esterase HSJS1_k127_4029228_3 215803.DB30_6858 1.258e-43 179.0 COG3055@1|root,COG5563@1|root,COG3055@2|Bacteria,COG5563@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Glyoxal oxidase N-terminus - - - - - - - - - - - - DUF1929,Glyoxal_oxid_N,Kelch_1,Kelch_4 HSJS1_k127_4029228_2 1313421.JHBV01000005_gene4608 3.624e-143 472.0 COG3204@1|root,COG3204@2|Bacteria,4P0KA@976|Bacteroidetes 976|Bacteroidetes P Parallel beta-helix repeats - - - - - - - - - - - - SdiA-regulated HSJS1_k127_4029228_5 1125701.HMPREF1221_00282 3.463e-25 109.0 2EDEG@1|root,337AV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_4029228_0 251221.35211765 2.204e-183 613.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_4029228_1 1278073.MYSTI_01766 4.364e-177 588.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria 1224|Proteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_4030115_6 443144.GM21_3549 0.0004289 53.0 COG0577@1|root,COG0577@2|Bacteria,1PU2M@1224|Proteobacteria,43AD5@68525|delta/epsilon subdivisions,2X65F@28221|Deltaproteobacteria 28221|Deltaproteobacteria V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX HSJS1_k127_4030115_2 443144.GM21_3550 4.519e-51 198.0 COG0577@1|root,COG0577@2|Bacteria,1PU2M@1224|Proteobacteria,43AD5@68525|delta/epsilon subdivisions 1224|Proteobacteria V ABC transporter, permease protein - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_4030115_1 204669.Acid345_1870 1.354e-79 282.0 COG0672@1|root,COG0672@2|Bacteria,3Y3XB@57723|Acidobacteria,2JI3D@204432|Acidobacteriia 204432|Acidobacteriia P PFAM Iron permease FTR1 - - - - - - - - - - - - DUF2318,FTR1 HSJS1_k127_4030115_3 247490.KSU1_D0967 4.714e-34 138.0 COG0735@1|root,COG0735@2|Bacteria,2IZJY@203682|Planctomycetes 203682|Planctomycetes P Belongs to the Fur family - - - ko:K03711 - - - - ko00000,ko03000 - - - FUR HSJS1_k127_4030115_5 997346.HMPREF9374_1278 0.0001618 50.0 2DRFR@1|root,33BIP@2|Bacteria,1UBQS@1239|Firmicutes,4IN5S@91061|Bacilli,27CBE@186824|Thermoactinomycetaceae 91061|Bacilli S Putative transmembrane protein (PGPGW) - - - - - - - - - - - - DUF454,PGPGW HSJS1_k127_4030115_0 518766.Rmar_2224 1.784e-194 621.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt HSJS1_k127_4030115_4 667014.Thein_0895 5.903e-16 78.0 COG0602@1|root,COG0602@2|Bacteria,2GHSM@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM HSJS1_k127_4045734_5 1267535.KB906767_gene5244 7.886e-24 109.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase HSJS1_k127_4045734_3 1125863.JAFN01000001_gene2374 3.114e-53 194.0 COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,42SKP@68525|delta/epsilon subdivisions,2WNEV@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit HSJS1_k127_4045734_0 1089547.KB913013_gene2103 2.045e-91 313.0 COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,47MQ3@768503|Cytophagia 976|Bacteroidetes O Pyridine nucleotide-disulphide oxidoreductase ypdA - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_3 HSJS1_k127_4045734_1 114615.BRADO5133 1.494e-66 249.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,3JRSS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin HSJS1_k127_4045734_4 861299.J421_2559 9.115e-47 179.0 COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes 142182|Gemmatimonadetes M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT HSJS1_k127_4045734_2 443144.GM21_1931 3.757e-64 244.0 COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,43SCM@69541|Desulfuromonadales 28221|Deltaproteobacteria S DHH family - - - - - - - - - - - - DHH,DHHA1 HSJS1_k127_4045734_6 1168034.FH5T_14775 6.695e-10 65.0 2EFWM@1|root,339NX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_4047509_3 485913.Krac_4861 7.438e-40 160.0 COG1878@1|root,COG1878@2|Bacteria,2G6WM@200795|Chloroflexi 200795|Chloroflexi S PFAM cyclase family protein - - - - - - - - - - - - Cyclase HSJS1_k127_4047509_0 861299.J421_0533 3.375e-83 282.0 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family - - 4.1.1.79 ko:K13039 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C HSJS1_k127_4047509_1 861299.J421_0534 1.047e-81 275.0 COG4032@1|root,COG4032@2|Bacteria 2|Bacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 4.1.1.79 ko:K06034 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_N HSJS1_k127_4047509_4 981384.AEYW01000013_gene517 3.217e-06 59.0 2EH77@1|root,33AZ1@2|Bacteria,1NMNZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4047509_2 290315.Clim_0381 6.062e-40 153.0 COG0394@1|root,COG0394@2|Bacteria,1FF6H@1090|Chlorobi 1090|Chlorobi T PFAM low molecular weight phosphotyrosine protein phosphatase - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc HSJS1_k127_4048729_0 204669.Acid345_0001 8.12e-134 441.0 COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria,2JHN7@204432|Acidobacteriia 204432|Acidobacteriia L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N HSJS1_k127_4048729_2 234267.Acid_0002 1.375e-79 278.0 COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria 57723|Acidobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria - - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 HSJS1_k127_4048729_3 566466.NOR53_3004 6.22e-36 150.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1J8RM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N HSJS1_k127_4048729_1 380703.AHA_0004 8.072e-105 349.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1Y43E@135624|Aeromonadales 135624|Aeromonadales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim HSJS1_k127_4049238_0 1123035.ARLA01000026_gene67 3e-96 331.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia,4C3KK@83612|Psychroflexus 976|Bacteroidetes M Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer HSJS1_k127_4049238_1 1121904.ARBP01000032_gene2005 1.591e-42 177.0 COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 HSJS1_k127_4052726_4 290397.Adeh_1631 2.556e-31 126.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YURZ@29|Myxococcales 28221|Deltaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM HSJS1_k127_4052726_5 1071679.BG57_15475 2.418e-30 136.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,1K3K8@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the multicopper oxidase YfiH RL5 family yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 HSJS1_k127_4052726_3 489653.NLA_6070 1.326e-31 142.0 COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,2WEFV@28216|Betaproteobacteria,2KQY6@206351|Neisseriales 206351|Neisseriales E Psort location Periplasmic, score 9.44 - - - - - - - - - - - - Lipase_GDSL_2 HSJS1_k127_4052726_0 1125863.JAFN01000001_gene1605 1.255e-132 457.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey HSJS1_k127_4052726_1 903818.KI912268_gene2501 1.171e-75 262.0 COG2884@1|root,COG2884@2|Bacteria 2|Bacteria D Cell division ATP-binding protein ftsE ftsE GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - ko:K09811,ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran HSJS1_k127_4052726_2 338963.Pcar_1675 1.556e-38 160.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,43SGA@69541|Desulfuromonadales 28221|Deltaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX HSJS1_k127_4052726_7 748280.NH8B_3466 1.365e-14 82.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,2KPN9@206351|Neisseriales 206351|Neisseriales M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA HSJS1_k127_4052726_6 1499967.BAYZ01000030_gene1167 1.173e-15 85.0 COG1520@1|root,COG1572@1|root,COG3210@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3210@2|Bacteria,2NRGG@2323|unclassified Bacteria 2|Bacteria U Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - 1.1.2.6 ko:K05889,ko:K12678 - - R03136 - ko00000,ko01000,ko02000,ko02044 1.B.12.1.1,1.B.12.1.3 - - CARDB,Cadherin-like,Calx-beta,Chlam_PMP,Flg_new,Lectin_legB,PQQ_2,SLH HSJS1_k127_4057401_0 1297742.A176_06444 1.325e-112 393.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales 28221|Deltaproteobacteria V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_4057401_1 671143.DAMO_0822 4.48e-68 255.0 COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria 2|Bacteria C Cytochrome c554 and c-prime - - - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB HSJS1_k127_4065876_5 1267535.KB906767_gene623 1.181e-32 136.0 COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia 204432|Acidobacteriia S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 HSJS1_k127_4065876_1 234267.Acid_3868 3.095e-69 240.0 COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria 57723|Acidobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux HSJS1_k127_4065876_9 686340.Metal_3696 1.994e-06 54.0 2ED2F@1|root,336ZC@2|Bacteria,1N758@1224|Proteobacteria,1SE5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 HSJS1_k127_4065876_3 883126.HMPREF9710_04137 2.035e-52 211.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2W1RC@28216|Betaproteobacteria 28216|Betaproteobacteria S Kelch motif - - - - - - - - - - - - Kelch_1,Kelch_6 HSJS1_k127_4065876_7 529818.AMSG_00194T0 4.549e-12 80.0 KOG1306@1|root,KOG1306@2759|Eukaryota 2759|Eukaryota P calcium:sodium antiporter activity - - - - - - - - - - - - Calx-beta,fn3 HSJS1_k127_4065876_6 215803.DB30_7638 2.121e-16 87.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales 28221|Deltaproteobacteria S Smr domain - - - - - - - - - - - - Smr HSJS1_k127_4065876_0 317619.ANKN01000071_gene2928 5.939e-81 289.0 COG3011@1|root,COG3011@2|Bacteria,1FZYP@1117|Cyanobacteria 1117|Cyanobacteria S HTTM domain protein - - - - - - - - - - - - DUF393,VKG_Carbox HSJS1_k127_4065876_2 349124.Hhal_0101 4.191e-66 231.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WXZK@135613|Chromatiales 135613|Chromatiales O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA HSJS1_k127_4065876_4 234267.Acid_5856 1.794e-44 180.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase HSJS1_k127_4071599_3 502025.Hoch_1712 6.036e-25 112.0 COG2312@1|root,COG2312@2|Bacteria,1ND2M@1224|Proteobacteria,43DU1@68525|delta/epsilon subdivisions,2WYVB@28221|Deltaproteobacteria,2Z0QG@29|Myxococcales 28221|Deltaproteobacteria S Erythromycin esterase - - - - - - - - - - - - Erythro_esteras HSJS1_k127_4071599_0 1300345.LF41_1080 9.607e-149 491.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1XA6G@135614|Xanthomonadales 135614|Xanthomonadales S COG0457 FOG TPR repeat - - - - - - - - - - - - - HSJS1_k127_4071599_2 1379281.AVAG01000027_gene1689 1.302e-28 119.0 COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WP5S@28221|Deltaproteobacteria,2MC10@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM CBS domain containing protein - - - ko:K07168 - - - - ko00000 - - - CBS HSJS1_k127_4071599_1 1121920.AUAU01000008_gene1590 9.069e-93 321.0 COG0167@1|root,COG0167@2|Bacteria,3Y464@57723|Acidobacteria 57723|Acidobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh HSJS1_k127_4078587_0 319795.Dgeo_0333 2.732e-48 186.0 COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H PFAM Mur ligase family, glutamate ligase domain - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M HSJS1_k127_4078587_1 243090.RB13330 7.2e-07 59.0 COG0457@1|root,COG5305@1|root,COG0457@2|Bacteria,COG5305@2|Bacteria 2|Bacteria S peptidyl-tyrosine sulfation - - - - - - - - - - - - PMT_2 HSJS1_k127_4086533_2 246197.MXAN_1145 6.926e-34 140.0 COG4235@1|root,COG4235@2|Bacteria 2|Bacteria O cytochrome complex assembly - - - ko:K02200,ko:K04018 - - - - ko00000 - - - DUF4388,TPR_16,TPR_19,TPR_2 HSJS1_k127_4086533_1 1094980.Mpsy_2165 1.714e-41 157.0 COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia 224756|Methanomicrobia S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 HSJS1_k127_4086533_0 575540.Isop_1210 1.819e-228 719.0 COG4447@1|root,COG4447@2|Bacteria,2J1J5@203682|Planctomycetes 203682|Planctomycetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 HSJS1_k127_4088627_2 667014.Thein_1267 2.528e-21 94.0 COG1418@1|root,COG3064@1|root,COG1418@2|Bacteria,COG3064@2|Bacteria,2GGRQ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 HSJS1_k127_4088627_0 1232410.KI421425_gene1520 1.003e-86 297.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales 28221|Deltaproteobacteria S YmdB-like protein - - - ko:K09769 - - - - ko00000 - - - YmdB HSJS1_k127_4088627_1 1125863.JAFN01000001_gene685 2.097e-57 207.0 COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_4095705_0 882378.RBRH_00456 2.988e-118 397.0 COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,2VMZS@28216|Betaproteobacteria,1K35W@119060|Burkholderiaceae 28216|Betaproteobacteria L Evidence 2b Function of strongly homologous gene - - - - - - - - - - - - rve HSJS1_k127_4095705_1 1121438.JNJA01000061_gene3336 4.532e-72 261.0 COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2MGH2@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM IstB domain protein ATP-binding protein - - - - - - - - - - - - IstB_IS21 HSJS1_k127_4095705_2 1316936.K678_11970 7.967e-08 62.0 COG0433@1|root,COG0433@2|Bacteria,1R4SG@1224|Proteobacteria,2U2HY@28211|Alphaproteobacteria,2JVDA@204441|Rhodospirillales 204441|Rhodospirillales S AAA-like domain - - - - - - - - - - - - TraG-D_C HSJS1_k127_4103126_1 1267535.KB906767_gene3985 4.792e-07 57.0 COG0526@1|root,COG0526@2|Bacteria,3Y4UN@57723|Acidobacteria 57723|Acidobacteria CO PFAM Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin HSJS1_k127_4103126_0 935567.JAES01000059_gene546 4.267e-32 136.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1X691@135614|Xanthomonadales 135614|Xanthomonadales S competence protein comF - - - - - - - - - - - Pribosyltran HSJS1_k127_4106348_3 1125863.JAFN01000001_gene2986 2.486e-18 88.0 COG1611@1|root,COG1611@2|Bacteria,1RJ91@1224|Proteobacteria,42TR7@68525|delta/epsilon subdivisions,2WQUE@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM conserved - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DNA_processg_A,Lysine_decarbox HSJS1_k127_4106348_2 42256.RradSPS_2525 1.012e-36 149.0 COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigK - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 HSJS1_k127_4106348_1 234267.Acid_2708 1.667e-56 208.0 COG4221@1|root,COG4221@2|Bacteria,3Y4DX@57723|Acidobacteria 57723|Acidobacteria S KR domain - - - - - - - - - - - - adh_short HSJS1_k127_4106348_0 1123242.JH636434_gene4022 2.452e-80 274.0 COG2738@1|root,COG2738@2|Bacteria,2IZDM@203682|Planctomycetes 203682|Planctomycetes S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 HSJS1_k127_4106348_4 146922.JOFU01000045_gene5585 2.372e-14 74.0 COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria 201174|Actinobacteria G the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells manB - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV HSJS1_k127_4110178_0 1279019.ARQK01000049_gene41 1.815e-198 629.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim HSJS1_k127_4110178_2 1121920.AUAU01000011_gene189 5.47e-68 253.0 COG1716@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria 57723|Acidobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,GAF_3,SpoIIE HSJS1_k127_4110178_3 511051.CSE_09940 6.319e-23 106.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis resA - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Thioredoxin_8 HSJS1_k127_4110178_4 290397.Adeh_1537 1.039e-09 66.0 COG2210@1|root,COG2210@2|Bacteria 2|Bacteria P Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - DrsE,DrsE_2 HSJS1_k127_4110178_1 298655.KI912266_gene3140 2.746e-79 282.0 COG0457@1|root,COG0457@2|Bacteria,2GIWN@201174|Actinobacteria,4ETW8@85013|Frankiales 201174|Actinobacteria K PFAM NB-ARC domain - - - - - - - - - - - - NB-ARC,TIR_2,TPR_10,TPR_12,TPR_4,TPR_7,TPR_8 HSJS1_k127_4117270_2 1173028.ANKO01000014_gene1070 2.457e-09 70.0 COG2931@1|root,COG2931@2|Bacteria,1GFGD@1117|Cyanobacteria 1117|Cyanobacteria Q domain, Protein - - - - - - - - - - - - - HSJS1_k127_4117270_0 1125863.JAFN01000001_gene3134 2.774e-49 198.0 COG2050@1|root,COG3303@1|root,COG2050@2|Bacteria,COG3303@2|Bacteria,1R0AE@1224|Proteobacteria,43CSS@68525|delta/epsilon subdivisions,2WU2I@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554 HSJS1_k127_4117270_1 234267.Acid_7896 2.449e-41 173.0 COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria 57723|Acidobacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 HSJS1_k127_4128508_0 1128421.JAGA01000002_gene1149 1.827e-45 173.0 COG4770@1|root,COG4770@2|Bacteria 2|Bacteria I CoA carboxylase activity - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 HSJS1_k127_4134955_1 867903.ThesuDRAFT_00284 1.575e-123 422.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,3WDT5@538999|Clostridiales incertae sedis 186801|Clostridia J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO - 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA HSJS1_k127_4134955_0 246197.MXAN_1695 6.491e-200 650.0 COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria 1224|Proteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_4134955_2 243090.RB7957 4.526e-82 279.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2IY53@203682|Planctomycetes 203682|Planctomycetes L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom HSJS1_k127_4135001_0 215803.DB30_8925 1.064e-18 98.0 2BR3U@1|root,32K1T@2|Bacteria,1Q2KE@1224|Proteobacteria,433U9@68525|delta/epsilon subdivisions,2X3H0@28221|Deltaproteobacteria,2YW23@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4143790_3 671143.DAMO_2726 2.61e-14 74.0 COG3654@1|root,COG3654@2|Bacteria,2NRTS@2323|unclassified Bacteria 2|Bacteria S Fic/DOC family doc - - ko:K07341 - - - - ko00000,ko02048 - - - Fic HSJS1_k127_4143790_2 671143.DAMO_2725 2.415e-18 86.0 COG2336@1|root,COG2336@2|Bacteria 2|Bacteria T PFAM SpoVT AbrB - - - ko:K07172,ko:K18842 - - - - ko00000,ko02048 - - - MazE_antitoxin HSJS1_k127_4143790_0 391625.PPSIR1_00807 1.295e-131 430.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43BP2@68525|delta/epsilon subdivisions,2WK8X@28221|Deltaproteobacteria 28221|Deltaproteobacteria C molybdopterin oxidoreductase Fe4S4 region sfrA - 1.17.1.10 ko:K05299 ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200 M00377 R00134 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer2_4,Fer4_10,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 HSJS1_k127_4143790_1 391625.PPSIR1_00812 4.657e-89 297.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 HSJS1_k127_4149215_1 1121035.AUCH01000007_gene473 6.702e-19 97.0 COG0589@1|root,COG0589@2|Bacteria,1PE08@1224|Proteobacteria,2VNHV@28216|Betaproteobacteria,2KVV6@206389|Rhodocyclales 206389|Rhodocyclales T Universal stress protein family uspA - - - - - - - - - - - Usp HSJS1_k127_4149215_0 1382306.JNIM01000001_gene1023 4.445e-57 211.0 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrA - 1.3.7.9 ko:K04108 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 HSJS1_k127_4152014_2 1121403.AUCV01000018_gene3212 1.369e-100 336.0 COG2116@1|root,COG2116@2|Bacteria,1N8YM@1224|Proteobacteria 1224|Proteobacteria P Formate nitrite yfdC GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015318,GO:0015499,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K21990 - - - - ko00000 1.A.16.4 - - Form_Nir_trans HSJS1_k127_4152014_0 335543.Sfum_0872 1.635e-192 616.0 COG1847@1|root,COG3854@1|root,COG1847@2|Bacteria,COG3854@2|Bacteria,1MWTB@1224|Proteobacteria,42P75@68525|delta/epsilon subdivisions,2WJX3@28221|Deltaproteobacteria 28221|Deltaproteobacteria S R3H domain - - - - - - - - - - - - R3H HSJS1_k127_4152014_3 1232410.KI421426_gene1437 3.545e-65 230.0 arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria,43UQJ@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4152014_4 1121405.dsmv_0256 7.305e-55 208.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales 28221|Deltaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport HSJS1_k127_4152014_1 1121930.AQXG01000001_gene1099 4.265e-112 371.0 COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1IUV5@117747|Sphingobacteriia 976|Bacteroidetes E Pyridoxal-phosphate dependent enzyme ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP HSJS1_k127_4152014_5 215803.DB30_0854 2.028e-34 141.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales 28221|Deltaproteobacteria E Aminotransferase class I and II - - 2.6.1.17 ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HSJS1_k127_4153592_1 1121456.ATVA01000011_gene1678 5.051e-98 331.0 COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,42Q4Z@68525|delta/epsilon subdivisions,2WM28@28221|Deltaproteobacteria,2M9SQ@213115|Desulfovibrionales 28221|Deltaproteobacteria G PFAM Glycoside hydrolase family 65, central catalytic - - - - - - - - - - - - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase HSJS1_k127_4153592_2 880073.Calab_2976 3.993e-58 208.0 COG0572@1|root,COG0572@2|Bacteria,2NRHW@2323|unclassified Bacteria 2|Bacteria F Phosphoribulokinase / Uridine kinase family - - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - AAA_18,AAA_33,Hydrolase_like,NTP_transferase,PRK,RNA_lig_T4_1 HSJS1_k127_4153592_0 1238182.C882_4345 3.631e-175 562.0 COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,2TXK8@28211|Alphaproteobacteria,2JVHU@204441|Rhodospirillales 204441|Rhodospirillales E Sodium:solute symporter family - - - - - - - - - - - - SSF HSJS1_k127_416618_3 171693.BN988_02662 5.997e-34 141.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,23K62@182709|Oceanobacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N HSJS1_k127_416618_2 1304880.JAGB01000002_gene2311 1.944e-120 401.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C HSJS1_k127_416618_0 1027273.GZ77_19935 5.634e-198 628.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1XIGE@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N HSJS1_k127_416618_1 1121271.AUCM01000005_gene597 1.83e-129 429.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS HSJS1_k127_4166915_3 517418.Ctha_2584 1.255e-17 98.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - 3.4.21.62 ko:K01342,ko:K12287,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko02044,ko03110 - - - FG-GAP,Peptidase_S8,VCBS HSJS1_k127_4166915_1 644282.Deba_1484 1.007e-19 97.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 HSJS1_k127_4166915_2 404589.Anae109_1863 4.277e-18 95.0 COG0745@1|root,COG0745@2|Bacteria 404589.Anae109_1863|- T phosphorelay signal transduction system - - - - - - - - - - - - - HSJS1_k127_4166915_0 1385519.N801_03125 7.17e-32 133.0 COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4FF2H@85021|Intrasporangiaceae 201174|Actinobacteria H molybdopterin moeA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 ko:K00963,ko:K03750 ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130 M00129,M00361,M00362,M00549 R00289,R09735 RC00002,RC03462 ko00000,ko00001,ko00002,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N HSJS1_k127_4172051_8 316055.RPE_4100 4.674e-40 152.0 COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2U8GF@28211|Alphaproteobacteria,3JYGY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Fic/DOC family doc - - ko:K07341 - - - - ko00000,ko02048 - - - Fic HSJS1_k127_4172051_9 309807.SRU_2815 2.09e-22 100.0 COG2336@1|root,COG2336@2|Bacteria 2|Bacteria T PFAM SpoVT AbrB - - - ko:K07172,ko:K18842 - - - - ko00000,ko02048 - - - MazE_antitoxin HSJS1_k127_4172051_4 1458427.BAWN01000018_gene1129 1.175e-55 201.0 COG4636@1|root,COG4636@2|Bacteria,1RDIC@1224|Proteobacteria,2VS19@28216|Betaproteobacteria,4AF70@80864|Comamonadaceae 28216|Betaproteobacteria S Putative restriction endonuclease - - - - - - - - - - - - Uma2 HSJS1_k127_4172051_10 391603.FBALC1_09537 3.43e-06 53.0 COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia 976|Bacteroidetes V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase,DUF3471,TPR_2,TPR_8 HSJS1_k127_4172051_7 861299.J421_0735 2.413e-44 171.0 COG0457@1|root,COG0457@2|Bacteria 861299.J421_0735|- S peptidyl-tyrosine sulfation - - - ko:K13992 - - - - ko00000,ko00194 - - - - HSJS1_k127_4172051_3 1366050.N234_18565 8.648e-77 284.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,1KCC6@119060|Burkholderiaceae 28216|Betaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep HSJS1_k127_4172051_11 1173024.KI912150_gene1478 0.0001383 51.0 COG4319@1|root,COG4319@2|Bacteria,1GDN0@1117|Cyanobacteria,1JJGB@1189|Stigonemataceae 1117|Cyanobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 HSJS1_k127_4172051_12 382464.ABSI01000006_gene839 0.0001842 55.0 COG0607@1|root,315D1@2|Bacteria,46TC5@74201|Verrucomicrobia 74201|Verrucomicrobia P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 HSJS1_k127_4172051_1 926550.CLDAP_29660 1.006e-116 388.0 COG1748@1|root,COG1748@2|Bacteria 2|Bacteria E saccharopine dehydrogenase activity - - - - - - - - - - - - ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP HSJS1_k127_4172051_6 591157.SSLG_02165 9.061e-46 192.0 COG1579@1|root,COG2128@1|root,COG1579@2|Bacteria,COG2128@2|Bacteria,2ICI6@201174|Actinobacteria 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD HSJS1_k127_4172051_0 886293.Sinac_2122 9.306e-143 470.0 COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes 203682|Planctomycetes E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 HSJS1_k127_4172051_2 502025.Hoch_0696 6.764e-81 284.0 28IKZ@1|root,2Z8MJ@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1702) - - - ko:K21161 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002 - - - DUF1702 HSJS1_k127_4172051_5 502025.Hoch_0695 5.36e-54 199.0 COG4658@1|root,COG4658@2|Bacteria,1QX8H@1224|Proteobacteria,43C1J@68525|delta/epsilon subdivisions,2X7C7@28221|Deltaproteobacteria,2YXH2@29|Myxococcales 2|Bacteria C ASPIC and UnbV - - 1.6.5.8 ko:K00347,ko:K03614,ko:K21162,ko:K21163 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002,ko01000 - - - NQR2_RnfD_RnfE,UnbV_ASPIC,VCBS HSJS1_k127_4175337_2 880071.Fleli_1862 2.339e-67 250.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47X9F@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - Sulfatase HSJS1_k127_4175337_1 330214.NIDE1393 1.765e-165 534.0 COG0034@1|root,COG0034@2|Bacteria,3J0C5@40117|Nitrospirae 40117|Nitrospirae F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_7,Pribosyltran HSJS1_k127_4175337_3 234267.Acid_6173 1.657e-06 51.0 COG1741@1|root,COG1741@2|Bacteria,3Y367@57723|Acidobacteria 57723|Acidobacteria S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C HSJS1_k127_4175337_0 861299.J421_0838 5.866e-190 606.0 COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1ZV6A@142182|Gemmatimonadetes 142182|Gemmatimonadetes P Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 HSJS1_k127_4181303_6 1499967.BAYZ01000157_gene585 1.108e-52 191.0 COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria 2|Bacteria S Bifunctional nuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03617,ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR HSJS1_k127_4181303_3 1047013.AQSP01000134_gene1378 9.005e-86 290.0 COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria 2|Bacteria D Cobyrinic acid ac-diamide synthase parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 HSJS1_k127_4181303_5 1047013.AQSP01000134_gene1379 2.765e-54 201.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc HSJS1_k127_4181303_2 1047013.AQSP01000132_gene1731 8.503e-118 409.0 COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria 2|Bacteria S Permease YjgP YjgQ family protein lptF - - ko:K07091,ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ HSJS1_k127_4181303_8 1089545.KB913037_gene661 1.097e-10 70.0 COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4E333@85010|Pseudonocardiales 201174|Actinobacteria K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4 HSJS1_k127_4181303_10 1157637.KB892102_gene1509 5.982e-06 59.0 COG1396@1|root,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,HTH_31,TPR_12,TPR_16,TPR_8 HSJS1_k127_4181303_9 1282360.ABAC460_23240 2.354e-07 59.0 COG1595@1|root,COG1595@2|Bacteria,1N0F6@1224|Proteobacteria,2UDCB@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 HSJS1_k127_4181303_0 234267.Acid_5274 2.769e-166 531.0 COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria 57723|Acidobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N HSJS1_k127_4181303_7 429009.Adeg_0537 9.567e-37 150.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,42GJG@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind HSJS1_k127_4181303_4 1185876.BN8_03503 5.579e-62 222.0 COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,47PQK@768503|Cytophagia 976|Bacteroidetes G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB HSJS1_k127_4181303_1 309807.SRU_2184 2.612e-129 419.0 COG0812@1|root,COG0812@2|Bacteria,4PEBS@976|Bacteroidetes,1FISG@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C HSJS1_k127_418190_0 394.NGR_c22070 2.028e-106 352.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2U2JT@28211|Alphaproteobacteria,4BB5D@82115|Rhizobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF2 - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB HSJS1_k127_418190_1 395493.BegalDRAFT_1882 9.904e-39 151.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,460R3@72273|Thiotrichales 72273|Thiotrichales C NADH dehydrogenase nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx HSJS1_k127_418190_2 1502850.FG91_03969 9.4e-23 104.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,2K4KM@204457|Sphingomonadales 204457|Sphingomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 HSJS1_k127_418190_3 1446473.JHWH01000003_gene3326 4.748e-09 63.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,2TSY6@28211|Alphaproteobacteria,2PVXA@265|Paracoccus 28211|Alphaproteobacteria K AraC-like ligand binding domain pobR - - ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 HSJS1_k127_4184967_3 869210.Marky_0500 5.137e-75 266.0 COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH HSJS1_k127_4184967_2 502025.Hoch_5756 7.022e-81 301.0 COG2133@1|root,COG2133@2|Bacteria,1PG5V@1224|Proteobacteria,4389W@68525|delta/epsilon subdivisions,2XA3Y@28221|Deltaproteobacteria,2YWB0@29|Myxococcales 28221|Deltaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH HSJS1_k127_4184967_1 869210.Marky_0500 1.981e-100 361.0 COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH HSJS1_k127_4184967_4 266117.Rxyl_2043 9.648e-42 157.0 COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria 84995|Rubrobacteria H Transcriptional coactivator pterin dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a HSJS1_k127_4184967_0 1121920.AUAU01000021_gene2510 1.963e-204 646.0 COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,3Y3G3@57723|Acidobacteria 57723|Acidobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.7 ko:K00187 ko00280,ko01100,map00280,map01100 - R07160,R08566,R08567 RC00004,RC02833,RC02856 br01601,ko00000,ko00001,ko01000 - - - POR,TPP_enzyme_C HSJS1_k127_4184967_5 1121920.AUAU01000021_gene2509 5.044e-09 61.0 COG0674@1|root,COG0674@2|Bacteria,3Y3NB@57723|Acidobacteria 57723|Acidobacteria C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.7 ko:K00186 ko00280,ko01100,map00280,map01100 - R07160,R08566,R08567 RC00004,RC02833,RC02856 br01601,ko00000,ko00001,ko01000 - - - PFOR_II,POR_N HSJS1_k127_4187328_2 1379270.AUXF01000002_gene1363 2.918e-66 244.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec HSJS1_k127_4187328_1 1121472.AQWN01000009_gene340 6.715e-71 260.0 COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,260K8@186807|Peptococcaceae 186801|Clostridia P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N HSJS1_k127_4187328_0 1449126.JQKL01000039_gene1064 5.712e-125 419.0 COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,268EF@186813|unclassified Clostridiales 186801|Clostridia P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH HSJS1_k127_4187328_3 526225.Gobs_3656 5.626e-07 62.0 COG2050@1|root,COG2050@2|Bacteria,2H1IE@201174|Actinobacteria 201174|Actinobacteria Q Thioesterase superfamily - - - - - - - - - - - - 4HBT HSJS1_k127_4194948_0 867845.KI911784_gene820 1.53e-75 268.0 COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi,3752D@32061|Chloroflexia 32061|Chloroflexia C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding HSJS1_k127_419571_5 1122138.AQUZ01000056_gene6944 3.033e-75 259.0 COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4DPP6@85009|Propionibacteriales 201174|Actinobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB HSJS1_k127_419571_2 1191523.MROS_2032 4.662e-104 360.0 COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria 2|Bacteria C formate dehydrogenase (NAD+) activity nuoG - 1.12.1.2,1.6.5.3 ko:K00336,ko:K18006 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 HSJS1_k127_419571_4 945713.IALB_0894 1.655e-89 322.0 COG1005@1|root,COG1005@2|Bacteria 2|Bacteria C quinone binding nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh HSJS1_k127_419571_10 1121930.AQXG01000002_gene2034 1.91e-16 93.0 COG0839@1|root,COG0839@2|Bacteria,4NNMC@976|Bacteroidetes,1ISZK@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 HSJS1_k127_419571_8 639030.JHVA01000001_gene776 1.474e-28 119.0 COG0713@1|root,COG0713@2|Bacteria,3Y4XI@57723|Acidobacteria,2JJIM@204432|Acidobacteriia 204432|Acidobacteriia C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 HSJS1_k127_419571_0 1125863.JAFN01000001_gene2410 2.474e-171 559.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria 28221|Deltaproteobacteria CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein nuoL-1 - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N HSJS1_k127_419571_1 1379698.RBG1_1C00001G1061 4.805e-145 479.0 COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria 2|Bacteria C NADH-quinone oxidoreductase, chain M nuoM-1 - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M HSJS1_k127_419571_3 443144.GM21_3997 1.817e-97 335.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M HSJS1_k127_419571_6 1121468.AUBR01000020_gene2849 9.176e-46 175.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,42FJD@68295|Thermoanaerobacterales 186801|Clostridia K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N HSJS1_k127_419571_7 479434.Sthe_1779 4.702e-38 162.0 COG1807@1|root,COG1807@2|Bacteria,2GBE9@200795|Chloroflexi,27Z44@189775|Thermomicrobia 189775|Thermomicrobia M Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 HSJS1_k127_419571_9 869210.Marky_1233 7.881e-27 117.0 COG1086@1|root,COG1086@2|Bacteria 2|Bacteria GM Polysaccharide biosynthesis protein - - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD HSJS1_k127_4205178_4 1121104.AQXH01000003_gene325 2.7e-79 281.0 COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1IRKN@117747|Sphingobacteriia 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 HSJS1_k127_4205178_0 483219.LILAB_26520 1.123e-229 745.0 COG3227@1|root,COG3227@2|Bacteria,1QXPY@1224|Proteobacteria,43E6J@68525|delta/epsilon subdivisions,2X7H9@28221|Deltaproteobacteria,2Z3GG@29|Myxococcales 28221|Deltaproteobacteria E Fungalysin metallopeptidase (M36) - - - ko:K01417 - - - - ko00000,ko01000,ko01002 - - - FTP,Peptidase_M36 HSJS1_k127_4205178_8 204669.Acid345_3922 8.143e-21 96.0 COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria,2JJNQ@204432|Acidobacteriia 204432|Acidobacteriia K Regulatory protein - - - - - - - - - - - - MerR_1 HSJS1_k127_4205178_10 1122218.KB893654_gene2315 3.527e-15 89.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria,1JVC8@119045|Methylobacteriaceae 28211|Alphaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA - - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding HSJS1_k127_4205178_3 1050202.KB913024_gene1558 1.335e-105 357.0 COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,407NU@622450|Actinopolysporales 201174|Actinobacteria S AIG1 family der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K03977 - - - - ko00000,ko03009 - - - Cytidylate_kin,KH_dom-like,MMR_HSR1 HSJS1_k127_4205178_2 635013.TherJR_2693 8.795e-137 463.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,2634J@186807|Peptococcaceae 186801|Clostridia J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 HSJS1_k127_4205178_6 1343740.M271_25185 1.383e-38 149.0 COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria 201174|Actinobacteria O belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin HSJS1_k127_4205178_9 118005.AWNK01000001_gene1960 5.97e-20 93.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 HSJS1_k127_4205178_5 1121943.KB899994_gene991 4.602e-64 233.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales 135619|Oceanospirillales L TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase HSJS1_k127_4205178_1 198467.NP92_14260 2.998e-183 593.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,21W9P@150247|Anoxybacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind HSJS1_k127_4205178_7 1125863.JAFN01000001_gene1992 3.129e-21 97.0 COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria 28221|Deltaproteobacteria N Putative transposase, YhgA-like - - - - - - - - - - - - DUF4351,Transposase_31 HSJS1_k127_421059_0 443144.GM21_3259 1.858e-67 249.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales 28221|Deltaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase HSJS1_k127_4219992_5 1485545.JQLW01000007_gene799 3.543e-54 216.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria 1224|Proteobacteria V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HSJS1_k127_4219992_4 1144275.COCOR_02677 5.019e-88 305.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB HSJS1_k127_4219992_8 682795.AciX8_0672 2.338e-15 85.0 2DTIS@1|root,33KJ1@2|Bacteria,3Y5U4@57723|Acidobacteria,2JN6V@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - HSJS1_k127_4219992_7 204669.Acid345_4105 3.617e-33 132.0 COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia 204432|Acidobacteriia L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding HSJS1_k127_4219992_0 1499967.BAYZ01000095_gene4092 1.331e-185 610.0 COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S1 rpsA - 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - Cytidylate_kin,LYTB,S1 HSJS1_k127_4219992_3 1121104.AQXH01000008_gene2418 7.121e-132 434.0 COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IWYY@117747|Sphingobacteriia 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 HSJS1_k127_4219992_1 234267.Acid_3515 2.423e-169 591.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_4219992_2 1254432.SCE1572_21885 1.218e-143 503.0 COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,439ZZ@68525|delta/epsilon subdivisions,2X4EZ@28221|Deltaproteobacteria,2YYW8@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.77,1.2.1.91,3.3.2.12 ko:K02618,ko:K15514 ko00360,ko00362,ko01120,map00360,map00362,map01120 - R09554,R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - - Aldedh HSJS1_k127_4219992_6 468059.AUHA01000004_gene2375 1.901e-52 197.0 2BXBG@1|root,33WQF@2|Bacteria,4P3CB@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - HSJS1_k127_4222551_3 235985.BBPN01000009_gene3723 1.961e-10 75.0 2E2EJ@1|root,32XJ3@2|Bacteria,2ISI6@201174|Actinobacteria,2NKMK@228398|Streptacidiphilus 201174|Actinobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH HSJS1_k127_4222551_1 316274.Haur_3580 2.705e-56 217.0 COG2244@1|root,COG2244@2|Bacteria,2G7NK@200795|Chloroflexi,3761V@32061|Chloroflexia 32061|Chloroflexia S PFAM polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt_3,Polysacc_synt_C HSJS1_k127_4222551_0 357808.RoseRS_2371 5.416e-87 318.0 COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi,376I5@32061|Chloroflexia 32061|Chloroflexia H PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_4222551_2 383372.Rcas_3103 1.238e-11 70.0 COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia 32061|Chloroflexia M PFAM O-antigen polymerase - - - - - - - - - - - - Wzy_C HSJS1_k127_422393_2 1330700.JQNC01000003_gene1398 0.000459 53.0 COG0457@1|root,COG0457@2|Bacteria,1WJ9W@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Tetratricopeptide repeat - - - - - - - - - - - - ANAPC3,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8 HSJS1_k127_422393_1 682795.AciX8_3382 2.97e-08 67.0 COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia 204432|Acidobacteriia S oxidoreductase activity - - - - - - - - - - - - - HSJS1_k127_422393_0 631454.N177_3468 5.581e-51 181.0 28NR0@1|root,2ZBQD@2|Bacteria,1RA2I@1224|Proteobacteria,2U5BA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Nucleoside 2-deoxyribosyltransferase YtoQ ytoQ - - - - - - - - - - - Nuc_deoxyri_tr3 HSJS1_k127_4226142_2 502025.Hoch_2002 1.107e-43 164.0 COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales 28221|Deltaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 HSJS1_k127_4226142_1 502025.Hoch_2001 1.837e-72 246.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z3A1@29|Myxococcales 28221|Deltaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518,ko:K13483 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Fer2_2 HSJS1_k127_4226142_0 502025.Hoch_2000 5.327e-214 687.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2 HSJS1_k127_4226216_8 1121481.AUAS01000017_gene2506 2.388e-05 49.0 COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes,47TM3@768503|Cytophagia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - HSJS1_k127_4226216_2 243233.MCA0444 2.831e-89 320.0 COG1858@1|root,COG1858@2|Bacteria,1RC4D@1224|Proteobacteria,1SJKT@1236|Gammaproteobacteria,1XFYK@135618|Methylococcales 135618|Methylococcales C cytochrome C peroxidase - - - - - - - - - - - - - HSJS1_k127_4226216_7 1123376.AUIU01000002_gene1666 6.202e-06 54.0 2DRP0@1|root,33CFM@2|Bacteria,3J1BN@40117|Nitrospirae 40117|Nitrospirae S Protein of unknown function (DUF465) - - - ko:K09794 - - - - ko00000 - - - DUF465 HSJS1_k127_4226216_3 1238190.AMQY01000001_gene598 5.896e-64 229.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1XIQ5@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf HSJS1_k127_4226216_6 1280390.CBQR020000024_gene510 5.643e-08 64.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,26RSN@186822|Paenibacillaceae 91061|Bacilli E Belongs to the aspartate-semialdehyde dehydrogenase family asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC HSJS1_k127_4226216_5 314278.NB231_00999 1.048e-30 124.0 COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,1SE9N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional - - - - - - - - - - - - AsnC_trans_reg HSJS1_k127_4226216_4 886293.Sinac_7157 2.929e-44 167.0 COG1528@1|root,COG1528@2|Bacteria 2|Bacteria P ferric iron binding ftn GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771 1.16.3.1,1.16.3.2 ko:K02217,ko:K22336 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin HSJS1_k127_4226216_0 518766.Rmar_0181 1.056e-126 418.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1FIUF@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 HSJS1_k127_4226216_1 1089550.ATTH01000001_gene1592 1.326e-108 361.0 COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1FIU1@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H magnesium chelatase chlI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - AAA_5,Sigma54_activat HSJS1_k127_423549_0 383372.Rcas_2386 6.192e-115 387.0 COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi 200795|Chloroflexi Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf HSJS1_k127_423549_1 649638.Trad_0575 1.094e-72 260.0 COG3823@1|root,COG3823@2|Bacteria,1WM89@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 HSJS1_k127_423549_2 502025.Hoch_6444 2.631e-07 55.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales 28221|Deltaproteobacteria S oligopeptide transporter, OPT family - - - - - - - - - - - - OPT HSJS1_k127_4238997_3 377629.TERTU_2775 7.518e-12 74.0 2C1UX@1|root,33FGU@2|Bacteria,1NQE8@1224|Proteobacteria,1SJFD@1236|Gammaproteobacteria,2PQ86@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4238997_2 1089550.ATTH01000001_gene506 2.853e-57 210.0 COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1FJ0J@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes D Cellulose biosynthesis protein BcsQ - - - - - - - - - - - - AAA_31 HSJS1_k127_4238997_0 1242864.D187_003597 2.979e-120 400.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales 28221|Deltaproteobacteria E Threonine dehydratase ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT,PALP,Thr_dehydrat_C HSJS1_k127_4238997_1 575540.Isop_2836 9.792e-87 300.0 COG3342@1|root,COG3409@1|root,COG3342@2|Bacteria,COG3409@2|Bacteria,2J3RN@203682|Planctomycetes 203682|Planctomycetes M Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028 HSJS1_k127_4247416_3 682795.AciX8_1275 1.799e-14 87.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - AhpC-TSA,Redoxin,Thioredoxin,Thioredoxin_9 HSJS1_k127_4247416_1 661478.OP10G_0994 3.01e-153 499.0 COG0076@1|root,COG0076@2|Bacteria 2|Bacteria E glutamate decarboxylase activity - - - - - - - - - - - - Pyridoxal_deC HSJS1_k127_4247416_0 1123377.AUIV01000003_gene1795 3.267e-275 882.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales 135614|Xanthomonadales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase HSJS1_k127_4247416_2 574966.KB898647_gene2429 2.498e-34 151.0 COG2911@1|root,COG2911@2|Bacteria,1N4HK@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - HSJS1_k127_4255506_0 1125863.JAFN01000001_gene1632 1.672e-98 344.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42Z38@68525|delta/epsilon subdivisions,2X5H0@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 HSJS1_k127_4255506_1 247634.GPB2148_1338 1.581e-52 209.0 COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,1RSAD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest HSJS1_k127_4257581_1 1121468.AUBR01000005_gene22 3.13e-49 183.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales 186801|Clostridia E PFAM aminotransferase, class I aspB - 2.6.1.1 ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - iHN637.CLJU_RS06550 Aminotran_1_2 HSJS1_k127_4257581_0 1117319.PSPO_20566 1.416e-255 803.0 COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,1RS2Q@1236|Gammaproteobacteria,2PZKK@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 HSJS1_k127_4271297_4 344747.PM8797T_21393 1.665e-23 102.0 COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes 203682|Planctomycetes C COG0644 Dehydrogenases (flavoproteins) - - - - - - - - - - - - Trp_halogenase HSJS1_k127_4271297_3 103690.17134062 3.495e-73 273.0 COG4774@1|root,COG4774@2|Bacteria 2|Bacteria P siderophore transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - AMIN,Plug,TonB_dep_Rec HSJS1_k127_4271297_2 240016.ABIZ01000001_gene1539 1.346e-74 282.0 COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia 74201|Verrucomicrobia S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_4271297_0 530564.Psta_4503 1.745e-156 506.0 COG0635@1|root,COG0635@2|Bacteria,2IY84@203682|Planctomycetes 203682|Planctomycetes H COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - - - - - - - - - - Radical_SAM HSJS1_k127_4271297_1 344747.PM8797T_21408 1.011e-76 269.0 COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes 203682|Planctomycetes S protein kinase related protein - - - - - - - - - - - - PQQ_2,PQQ_3 HSJS1_k127_4275243_1 1047013.AQSP01000138_gene1053 1.054e-33 150.0 COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria 2|Bacteria MU Outer membrane efflux protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP HSJS1_k127_4275243_0 215803.DB30_0768 2.934e-116 385.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU5K@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY HSJS1_k127_4281849_0 1121033.AUCF01000001_gene2006 4.929e-64 233.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2U1W8@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the folylpolyglutamate synthase family - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M HSJS1_k127_4281849_1 555779.Dthio_PD3795 7.306e-45 165.0 COG2337@1|root,COG2337@2|Bacteria,1MYU1@1224|Proteobacteria,42UNN@68525|delta/epsilon subdivisions,2WQA2@28221|Deltaproteobacteria,2MFFM@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toxic component of a toxin-antitoxin (TA) module - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin HSJS1_k127_4300253_1 373994.Riv7116_6035 3.586e-60 232.0 2DUPP@1|root,33RMC@2|Bacteria,1GEBD@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_4300253_2 1379270.AUXF01000003_gene3552 0.0005001 53.0 COG3055@1|root,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - Collagen_bind_2,DUF5060,Kelch_1,Kelch_6,Malectin,NPCBM HSJS1_k127_4300253_0 396595.TK90_1645 3.473e-171 556.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WZW1@135613|Chromatiales 135613|Chromatiales P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C HSJS1_k127_4303553_0 344747.PM8797T_03069 1.2e-63 241.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - DUF1501,Sulfatase HSJS1_k127_4307748_2 1134912.AJTV01000020_gene3146 1.251e-110 368.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,36ZVX@31993|Methylocystaceae 28211|Alphaproteobacteria C Domain of unknown function (DUF4070) - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM HSJS1_k127_4307748_4 394221.Mmar10_1241 3.788e-22 111.0 COG0457@1|root,COG3710@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,1PF3H@1224|Proteobacteria,2V7F9@28211|Alphaproteobacteria,43YSF@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - TPR_16,Trans_reg_C HSJS1_k127_4307748_3 483219.LILAB_22265 1.185e-73 266.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - - - - - - - - - - - HSJS1_k127_4307748_0 326427.Cagg_3834 8.447e-162 534.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,3756Y@32061|Chloroflexia 32061|Chloroflexia C TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig HSJS1_k127_4307748_1 935863.AWZR01000014_gene2987 1.272e-128 457.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235,PilZ HSJS1_k127_4311731_4 448385.sce0381 4.683e-32 137.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4311731_0 240015.ACP_3026 2.164e-149 502.0 COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria,2JIK6@204432|Acidobacteriia 204432|Acidobacteriia E Aromatic amino acid lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic HSJS1_k127_4311731_2 925409.KI911562_gene1433 2.101e-98 355.0 COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1INQH@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D HSJS1_k127_4311731_1 1229172.JQFA01000002_gene2473 1.458e-120 412.0 COG0534@1|root,COG0534@2|Bacteria,1G0XS@1117|Cyanobacteria,1H77K@1150|Oscillatoriales 1117|Cyanobacteria V efflux protein, MATE family - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE HSJS1_k127_4311731_6 1121396.KB893064_gene1156 1.576e-22 107.0 COG1102@1|root,COG1102@2|Bacteria,1R9XZ@1224|Proteobacteria,42R78@68525|delta/epsilon subdivisions,2WN7X@28221|Deltaproteobacteria,2MJR4@213118|Desulfobacterales 28221|Deltaproteobacteria F Cytidylate kinase-like family - - - - - - - - - - - - Cytidylate_kin2 HSJS1_k127_4311731_3 204669.Acid345_3335 2.454e-77 281.0 COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia 204432|Acidobacteriia T HD domain - - - - - - - - - - - - HD HSJS1_k127_4311731_5 1442599.JAAN01000014_gene3524 3.351e-28 118.0 COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1X42C@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase HSJS1_k127_4329257_1 1521187.JPIM01000158_gene1703 5.335e-89 298.0 COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,3769V@32061|Chloroflexia 32061|Chloroflexia S SMART von Willebrand factor, type A - - - ko:K07161 - - - - ko00000 - - - VWA_CoxE HSJS1_k127_4329257_2 1304275.C41B8_10605 8.858e-46 174.0 COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,1RQQB@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator ybiH GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141 - - - - - - - - - - DUF1956,TetR_N HSJS1_k127_4329257_0 1163408.UU9_03867 3.006e-102 346.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,1X5W0@135614|Xanthomonadales 135614|Xanthomonadales M Biotin-lipoyl like - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 HSJS1_k127_4329257_3 411464.DESPIG_03101 1.245e-08 58.0 COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,43BJ5@68525|delta/epsilon subdivisions,2X713@28221|Deltaproteobacteria,2MHB4@213115|Desulfovibrionales 28221|Deltaproteobacteria G PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_4330516_7 1396858.Q666_14175 1.354e-10 61.0 COG4115@1|root,COG4115@2|Bacteria,1N0WH@1224|Proteobacteria,1S8ZF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Addiction module toxin, Txe YoeB - - - - - - - - - - - - YoeB_toxin HSJS1_k127_4330516_2 290397.Adeh_0279 1.867e-87 304.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales 28221|Deltaproteobacteria H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C HSJS1_k127_4330516_3 1128421.JAGA01000003_gene2924 1.695e-67 237.0 2CAZH@1|root,2Z7RU@2|Bacteria,2NRIS@2323|unclassified Bacteria 2|Bacteria - - sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt HSJS1_k127_4330516_0 383372.Rcas_3080 6.104e-316 978.0 COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia 32061|Chloroflexia C TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C HSJS1_k127_4330516_1 28444.JODQ01000003_gene4777 3.925e-109 375.0 COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4EH4D@85012|Streptosporangiales 201174|Actinobacteria C 2Fe-2S iron-sulfur cluster binding domain sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_7,Fer4_8 HSJS1_k127_4330516_5 383372.Rcas_1675 2.547e-52 187.0 COG1487@1|root,COG1487@2|Bacteria 2|Bacteria S nuclease activity vapC - - ko:K18828 - - - - ko00000,ko01000,ko02048,ko03016 - - - PIN HSJS1_k127_4330516_4 351160.RRC173 1.204e-66 236.0 COG1896@1|root,arCOG04311@2157|Archaea 2157|Archaea S HD superfamily - - - ko:K07023 - - - - ko00000 - - - HD_3 HSJS1_k127_435863_1 338963.Pcar_0004 6.662e-128 421.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales 28221|Deltaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim HSJS1_k127_435863_0 671143.DAMO_2945 1.656e-312 978.0 COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria 2|Bacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV HSJS1_k127_435863_2 1121875.KB907546_gene2610 3.715e-29 119.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 HSJS1_k127_4358780_2 290397.Adeh_2405 1.629e-34 136.0 COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions 1224|Proteobacteria C PFAM Rieske 2Fe-2S domain pcmE - 1.10.9.1 ko:K02636,ko:K03886 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00151,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske HSJS1_k127_4358780_0 404589.Anae109_0242 4.027e-170 547.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,2Z31Y@29|Myxococcales 28221|Deltaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - - - - - - - - - - Cytochrom_B_C,Cytochrome_B HSJS1_k127_4358780_1 404589.Anae109_0243 7.457e-114 377.0 COG2010@1|root,COG2010@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Cytochrome c pcmF - - - - - - - - - - - Cytochrom_C HSJS1_k127_4360923_2 469371.Tbis_1618 6.187e-20 91.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4E0CI@85010|Pseudonocardiales 201174|Actinobacteria EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.13,5.4.99.2 ko:K01848,ko:K11942 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase HSJS1_k127_4360923_1 1210884.HG799463_gene9356 2.273e-61 243.0 COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,2J2QP@203682|Planctomycetes 203682|Planctomycetes T Y_Y_Y domain - - - - - - - - - - - - HATPase_c,Reg_prop,Y_Y_Y HSJS1_k127_4360923_0 756272.Plabr_2852 4.051e-90 302.0 COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes 203682|Planctomycetes C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C HSJS1_k127_4361393_0 575540.Isop_1210 2.572e-241 764.0 COG4447@1|root,COG4447@2|Bacteria,2J1J5@203682|Planctomycetes 203682|Planctomycetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 HSJS1_k127_4361393_1 1122939.ATUD01000001_gene334 2.055e-130 434.0 COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria 201174|Actinobacteria S cellulose binding - - - - - - - - - - - - BNR HSJS1_k127_4361393_3 1122939.ATUD01000001_gene333 5.681e-15 88.0 COG1977@1|root,COG1977@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process - - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS HSJS1_k127_4361393_2 56110.Oscil6304_0344 2.607e-59 208.0 COG0395@1|root,COG0395@2|Bacteria,1G0JV@1117|Cyanobacteria,1H7WS@1150|Oscillatoriales 2|Bacteria G PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 HSJS1_k127_4361796_0 237368.SCABRO_00535 6e-37 157.0 COG3637@1|root,COG3637@2|Bacteria,2J46X@203682|Planctomycetes 203682|Planctomycetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - HSJS1_k127_4361796_1 330214.NIDE3836 5.101e-30 132.0 COG2197@1|root,COG3290@1|root,COG2197@2|Bacteria,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity prhJ - - ko:K06375 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000 - - - GerE,HATPase_c,PAS,PAS_4,PAS_8,PAS_9,Response_reg HSJS1_k127_4366332_1 338963.Pcar_1232 6.92e-61 235.0 COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,43SCT@69541|Desulfuromonadales 28221|Deltaproteobacteria S 7TM-HD extracellular - - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD HSJS1_k127_4366332_0 1499967.BAYZ01000057_gene4687 7.804e-104 353.0 COG1702@1|root,COG1702@2|Bacteria,2NNZF@2323|unclassified Bacteria 2|Bacteria T PhoH-like protein phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06217 - - - - ko00000 - - - PhoH HSJS1_k127_4366332_2 204669.Acid345_1212 3.046e-50 180.0 COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria,2JI6S@204432|Acidobacteriia 57723|Acidobacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N HSJS1_k127_4376212_0 251221.35211765 1.07e-82 288.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HSJS1_k127_4376212_1 999541.bgla_2g18880 6.721e-45 177.0 COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VJF0@28216|Betaproteobacteria,1K43E@119060|Burkholderiaceae 28216|Betaproteobacteria CO cytochrome c biogenesis protein - - - - - - - - - - - - AhpC-TSA,DsbD,Redoxin HSJS1_k127_4378459_0 309807.SRU_1289 1.345e-161 531.0 COG1757@1|root,COG1757@2|Bacteria,4NHP9@976|Bacteroidetes,1FIXG@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Na H antiporter - - - - - - - - - - - - Na_H_antiporter HSJS1_k127_4378459_1 1048339.KB913029_gene3604 2.817e-147 479.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4ERDP@85013|Frankiales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA HSJS1_k127_4378459_2 1382356.JQMP01000004_gene670 1.344e-35 141.0 COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_4380026_2 1068980.ARVW01000001_gene3281 3.927e-24 108.0 COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DYZC@85010|Pseudonocardiales 201174|Actinobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_4380026_1 204669.Acid345_4313 4.831e-26 112.0 COG3795@1|root,COG3795@2|Bacteria,3Y5P2@57723|Acidobacteria,2JNPR@204432|Acidobacteriia 204432|Acidobacteriia S YCII-related domain - - - - - - - - - - - - YCII HSJS1_k127_4380026_3 661478.OP10G_4489 2.715e-23 109.0 2A52F@1|root,30TQU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_4380026_0 1444711.CCJF01000004_gene2462 2.715e-26 111.0 COG0322@1|root,COG0322@2|Bacteria,2JFUB@204428|Chlamydiae 204428|Chlamydiae L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_5,UVR,UvrC_HhH_N HSJS1_k127_4381734_1 889378.Spiaf_2110 2.141e-36 140.0 COG5405@1|root,COG5405@2|Bacteria,2J608@203691|Spirochaetes 203691|Spirochaetes O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome HSJS1_k127_4381734_0 1267535.KB906767_gene4424 2.285e-174 559.0 COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia 204432|Acidobacteriia O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small HSJS1_k127_4381734_2 278963.ATWD01000001_gene3043 1.667e-30 134.0 COG4733@1|root,COG4733@2|Bacteria,3Y53H@57723|Acidobacteria,2JJMD@204432|Acidobacteriia 204432|Acidobacteriia S Fibronectin type 3 domain - - - - - - - - - - - - - HSJS1_k127_4386965_3 204669.Acid345_4065 1.009e-07 62.0 COG2823@1|root,COG2823@2|Bacteria,3Y7Q9@57723|Acidobacteria,2JMV8@204432|Acidobacteriia 204432|Acidobacteriia S Periplasmic or secreted lipoprotein - - - - - - - - - - - - BON HSJS1_k127_4386965_1 1267533.KB906735_gene5073 8.087e-50 200.0 COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia 204432|Acidobacteriia S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 HSJS1_k127_4386965_0 1123376.AUIU01000015_gene432 1.237e-80 297.0 COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae 40117|Nitrospirae M Transglycosylase - - 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase HSJS1_k127_4386965_2 344747.PM8797T_15596 2.607e-23 102.0 2BZBR@1|root,32YH6@2|Bacteria,2J41E@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_4392220_2 1122931.AUAE01000001_gene774 1.785e-18 96.0 COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22XN2@171551|Porphyromonadaceae 976|Bacteroidetes T Tetratricopeptide repeat batE - - - - - - - - - - - SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2 HSJS1_k127_4392220_1 1125863.JAFN01000001_gene282 3.183e-119 399.0 COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA HSJS1_k127_4392220_0 1449350.OCH239_11710 6.741e-229 729.0 COG5184@1|root,COG5184@2|Bacteria,1R0N0@1224|Proteobacteria 1224|Proteobacteria DZ Uncharacterised protein family UPF0560 - - - - - - - - - - - - CarboxypepD_reg,UPF0560 HSJS1_k127_4393664_2 926554.KI912674_gene2576 7.426e-05 52.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB,DinB_2 HSJS1_k127_4393664_0 523791.Kkor_2400 2.198e-34 144.0 COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,1SAKR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - HSJS1_k127_4393664_1 1305737.JAFX01000001_gene2306 6.695e-20 91.0 COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia 976|Bacteroidetes V ABC-type multidrug transport system ATPase component - - - - - - - - - - - - ABC_tran HSJS1_k127_4395757_1 1117318.PRUB_22486 2.403e-30 134.0 2ET0D@1|root,33KIK@2|Bacteria,1NZGV@1224|Proteobacteria,1SQ9F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4395757_0 1121930.AQXG01000002_gene2106 7.306e-49 184.0 COG0464@1|root,COG0464@2|Bacteria,4P1Y0@976|Bacteroidetes 976|Bacteroidetes O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA HSJS1_k127_4401057_0 1198114.AciX9_2616 9.562e-96 318.0 COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria,2JI79@204432|Acidobacteriia 204432|Acidobacteriia V ABC transporter - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran HSJS1_k127_4401057_3 429009.Adeg_0838 2.003e-41 167.0 COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,42EU9@68295|Thermoanaerobacterales 186801|Clostridia S domain protein yicC - - - - - - - - - - - DUF1732,YicC_N HSJS1_k127_4401057_2 868864.Dester_0178 3.414e-49 183.0 COG0194@1|root,COG0194@2|Bacteria,2G3ZQ@200783|Aquificae 200783|Aquificae F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin HSJS1_k127_4401057_6 1382359.JIAL01000001_gene2780 0.0009015 46.0 COG1758@1|root,COG1758@2|Bacteria,3Y5Z6@57723|Acidobacteria,2JK65@204432|Acidobacteriia 204432|Acidobacteriia K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 HSJS1_k127_4401057_1 215803.DB30_7969 1.652e-61 227.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales 28221|Deltaproteobacteria L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG HSJS1_k127_4401057_4 251221.35211658 3.599e-21 109.0 COG3629@1|root,COG3629@2|Bacteria 2|Bacteria K phosphorelay signal transduction system - - - - - - - - - - - - AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,Trans_reg_C HSJS1_k127_4401057_5 1122927.KB895415_gene4795 0.000228 46.0 COG1231@1|root,COG1231@2|Bacteria,1VM1Q@1239|Firmicutes,4HS2U@91061|Bacilli,26WD3@186822|Paenibacillaceae 91061|Bacilli E Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase HSJS1_k127_4403463_1 1500894.JQNN01000001_gene1607 8.425e-40 149.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,473HQ@75682|Oxalobacteraceae 28216|Betaproteobacteria F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase HSJS1_k127_4403463_2 685727.REQ_16170 2.468e-16 88.0 COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4G25I@85025|Nocardiaceae 201174|Actinobacteria S GCN5-related N-acetyl-transferase - - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG HSJS1_k127_4403463_0 373903.Hore_14590 4.215e-194 619.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WA6Y@53433|Halanaerobiales 186801|Clostridia J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 HSJS1_k127_4413933_2 713587.THITH_10295 7.246e-11 66.0 COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,1RMG2@1236|Gammaproteobacteria,1WXDI@135613|Chromatiales 135613|Chromatiales KT PFAM Stage II sporulation E family protein - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - SpoIIE HSJS1_k127_4413933_0 290397.Adeh_3892 1.326e-314 996.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2YUEP@29|Myxococcales 28221|Deltaproteobacteria S Penicillin amidase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase HSJS1_k127_4413933_1 118166.JH976537_gene3002 2.41e-67 246.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales 1117|Cyanobacteria NU TPR repeat - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_7,TPR_8 HSJS1_k127_4426933_1 1125863.JAFN01000001_gene3028 1.607e-105 347.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD HSJS1_k127_4426933_2 235985.BBPN01000001_gene1376 6.833e-16 89.0 COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,2NFF5@228398|Streptacidiphilus 201174|Actinobacteria S RecX family recX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03565 - - - - ko00000,ko03400 - - - RecX HSJS1_k127_4426933_0 903818.KI912268_gene1402 2.728e-161 518.0 COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria 57723|Acidobacteria NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE HSJS1_k127_4436681_2 485916.Dtox_4155 4.211e-16 88.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae 186801|Clostridia K Belongs to the sigma-70 factor family. ECF subfamily algU - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_4436681_0 29581.BW37_00870 0.0 1329.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,2WBDI@28216|Betaproteobacteria,475K6@75682|Oxalobacteraceae 28216|Betaproteobacteria M Tricorn protease homolog - - - - - - - - - - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ HSJS1_k127_4436681_3 1300345.LF41_947 1.16e-11 69.0 2ANYG@1|root,2ZGFF@2|Bacteria,1QEQI@1224|Proteobacteria,1TBIU@1236|Gammaproteobacteria,1X94U@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - HSJS1_k127_4436681_4 479433.Caci_1944 5.475e-08 61.0 2DG6U@1|root,2ZURF@2|Bacteria,2HCGM@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - HSJS1_k127_4436681_1 861299.J421_6141 7.687e-67 246.0 COG0577@1|root,COG0577@2|Bacteria 861299.J421_6141|- V efflux transmembrane transporter activity - - - - - - - - - - - - - HSJS1_k127_444560_0 179408.Osc7112_1433 3.204e-162 522.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1H6Y0@1150|Oscillatoriales 1117|Cyanobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P HSJS1_k127_444560_2 1123073.KB899241_gene1744 5.325e-54 195.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales 135614|Xanthomonadales S FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P HSJS1_k127_444560_1 1168065.DOK_18955 2.28e-158 507.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,Lipase_2 HSJS1_k127_44976_2 391595.RLO149_c016650 4.205e-14 77.0 COG1506@1|root,COG1506@2|Bacteria,1QZ1F@1224|Proteobacteria 1224|Proteobacteria E peptidase - - - - - - - - - - - - - HSJS1_k127_44976_3 323261.Noc_0292 1.303e-07 64.0 COG1538@1|root,COG1538@2|Bacteria,1RDVP@1224|Proteobacteria,1S9NY@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP HSJS1_k127_44976_1 404589.Anae109_4095 1.481e-52 206.0 COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,42SFA@68525|delta/epsilon subdivisions,2WUV2@28221|Deltaproteobacteria,2YVKJ@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 HSJS1_k127_44976_0 768671.ThimaDRAFT_4574 1.056e-223 715.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,1WX26@135613|Chromatiales 135613|Chromatiales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran HSJS1_k127_4503_2 331869.BAL199_05309 1.534e-61 214.0 COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2TUD4@28211|Alphaproteobacteria,4BSTC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red HSJS1_k127_4503_0 1538295.JY96_00940 1.458e-86 314.0 28JTH@1|root,2Z9IS@2|Bacteria,1N22P@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4503_4 1298863.AUEP01000016_gene4269 9.907e-09 69.0 COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4DSSN@85009|Propionibacteriales 201174|Actinobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - HSJS1_k127_4503_1 396588.Tgr7_0594 4.112e-66 244.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_4503_3 690850.Desaf_2363 8.335e-30 125.0 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria 1224|Proteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - HSJS1_k127_465820_4 1382306.JNIM01000001_gene268 4.544e-07 55.0 COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi 200795|Chloroflexi I Belongs to the enoyl-CoA hydratase isomerase family - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 HSJS1_k127_465820_2 1121920.AUAU01000025_gene2317 1.731e-30 131.0 2ET40@1|root,33KN7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_465820_3 1149133.ppKF707_3310 9.377e-13 80.0 COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria 1236|Gammaproteobacteria H COG2104 Sulfur transfer protein involved in thiamine biosynthesis thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS HSJS1_k127_465820_1 472759.Nhal_3942 5.202e-85 291.0 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1WXVN@135613|Chromatiales 135613|Chromatiales G PfkB domain protein - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB HSJS1_k127_465820_0 1283300.ATXB01000001_gene479 9.115e-266 837.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1XDS7@135618|Methylococcales 135618|Methylococcales M Sucrose phosphate synthase, sucrose phosphatase-like - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1,S6PP HSJS1_k127_467937_0 1254432.SCE1572_44230 1.777e-93 311.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria,2YWY0@29|Myxococcales 28221|Deltaproteobacteria I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N HSJS1_k127_476256_2 1128421.JAGA01000002_gene758 7.898e-26 125.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF2974,DUF4214,FKBP_C,HCBP_related,HemolysinCabind,Lipase_3,Peptidase_M10,Peptidase_M10_C HSJS1_k127_476256_1 290340.AAur_3853 1.045e-48 199.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - CHU_C,DUF11,DUF4347,Gram_pos_anchor,SdrD_B HSJS1_k127_476256_0 234267.Acid_2212 5.039e-125 413.0 COG2304@1|root,COG2304@2|Bacteria,3Y33Z@57723|Acidobacteria 57723|Acidobacteria S Peptidase M64 N-terminus - - - - - - - - - - - - M64_N,Peptidase_M64 HSJS1_k127_479038_0 1167006.UWK_00893 2.844e-105 355.0 COG0628@1|root,COG0628@2|Bacteria,1NG06@1224|Proteobacteria,42RH3@68525|delta/epsilon subdivisions 1224|Proteobacteria S Transmembrane protein 43 - - - - - - - - - - - - TMEM43 HSJS1_k127_479038_1 1300345.LF41_1611 6.963e-37 147.0 COG1231@1|root,COG1231@2|Bacteria,1RA9M@1224|Proteobacteria,1S3DF@1236|Gammaproteobacteria,1XCPQ@135614|Xanthomonadales 135614|Xanthomonadales E Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase HSJS1_k127_479464_3 243233.MCA0317 2.372e-61 213.0 COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,1S012@1236|Gammaproteobacteria,1XDJS@135618|Methylococcales 135618|Methylococcales S 56kDa selenium binding protein (SBP56) - - - ko:K17285 - - - - ko00000,ko04147 - - - SBP56 HSJS1_k127_479464_4 1121878.AUGL01000009_gene3360 6.986e-56 205.0 COG1999@1|root,COG1999@2|Bacteria 2|Bacteria M signal sequence binding hyaE GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - ko:K03619 - - - - ko00000 - - - HyaE,SCO1-SenC HSJS1_k127_479464_0 765913.ThidrDRAFT_0544 9.182e-127 430.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1X14I@135613|Chromatiales 135613|Chromatiales C PFAM Di-heme cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C HSJS1_k127_479464_1 768671.ThimaDRAFT_3101 8.272e-120 396.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1WXRI@135613|Chromatiales 135613|Chromatiales E Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 HSJS1_k127_479464_2 671143.DAMO_1877 7.834e-105 365.0 COG5000@1|root,COG5000@2|Bacteria,2NQZA@2323|unclassified Bacteria 2|Bacteria T Multi-sensor signal transduction histidine kinase ntrB - 2.7.13.3 ko:K07710 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8 HSJS1_k127_479615_0 1267534.KB906755_gene4832 6.885e-46 188.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia 204432|Acidobacteriia KLT Tetratricopeptide repeats - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_2,Trans_reg_C HSJS1_k127_482393_1 1536772.R70723_13750 1.204e-06 58.0 COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli,26WR0@186822|Paenibacillaceae 91061|Bacilli S DinB superfamily yuaE - - - - - - - - - - - DinB_2 HSJS1_k127_482393_0 1192034.CAP_7107 2.967e-12 78.0 COG1807@1|root,COG1807@2|Bacteria,1QX93@1224|Proteobacteria,43C25@68525|delta/epsilon subdivisions,2X7CQ@28221|Deltaproteobacteria,2YUUE@29|Myxococcales 28221|Deltaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 HSJS1_k127_482748_0 32057.KB217478_gene7131 1.536e-55 220.0 COG0845@1|root,COG3670@1|root,COG0845@2|Bacteria,COG3670@2|Bacteria,1G0AF@1117|Cyanobacteria,1HJWV@1161|Nostocales 1117|Cyanobacteria Q PFAM Retinal pigment epithelial membrane protein - - - - - - - - - - - - RPE65 HSJS1_k127_482748_1 1500890.JQNL01000001_gene1692 2.862e-19 98.0 COG0644@1|root,COG0644@2|Bacteria,1MZ3Z@1224|Proteobacteria,1S47W@1236|Gammaproteobacteria,1X4IT@135614|Xanthomonadales 135614|Xanthomonadales C Halogenase - - - - - - - - - - - - Trp_halogenase HSJS1_k127_487088_0 1049564.TevJSym_au00220 2.548e-123 406.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1J4FT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV HSJS1_k127_487088_2 498761.HM1_2791 6.464e-93 319.0 COG0008@1|root,COG0008@2|Bacteria,1TVW7@1239|Firmicutes,24BG2@186801|Clostridia 186801|Clostridia J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c HSJS1_k127_487088_1 472759.Nhal_2426 9.831e-96 316.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim HSJS1_k127_493551_5 502025.Hoch_4038 9.998e-72 255.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2YV2N@29|Myxococcales 28221|Deltaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE,MFS_1 HSJS1_k127_493551_3 1049564.TevJSym_aq00670 3.542e-76 276.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfA - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr HSJS1_k127_493551_4 1049564.TevJSym_aq00680 3.195e-73 258.0 COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfE2 - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr HSJS1_k127_493551_6 1049564.TevJSym_aq00690 4.756e-55 216.0 COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport - - - - - - - - - - - - FMN_bind HSJS1_k127_493551_2 1049564.TevJSym_aq00700 2.941e-99 357.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE HSJS1_k127_493551_0 1049564.TevJSym_aq00710 5.003e-169 545.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB HSJS1_k127_493551_1 1049564.TevJSym_aq00810 4.038e-110 385.0 COG0674@1|root,COG1013@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria 2|Bacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin forE - 1.2.7.1 ko:K00171,ko:K00172,ko:K02573,ko:K03737,ko:K13795,ko:K18930 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - CCG,Fer4,Fer4_4,Fer4_6,Fer4_9,Nitroreductase,PFOR_II,POR,POR_N,TPP_enzyme_C HSJS1_k127_498274_3 449447.MAE_14020 7.71e-14 76.0 COG2337@1|root,COG2337@2|Bacteria,1G7HN@1117|Cyanobacteria 1117|Cyanobacteria L Toxic component of a toxin-antitoxin (TA) module - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin HSJS1_k127_498274_2 357804.Ping_2355 1.536e-21 96.0 2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,1S9KD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_498274_0 926549.KI421517_gene1535 2.926e-62 221.0 COG1670@1|root,COG1670@2|Bacteria,4NMRH@976|Bacteroidetes,47QKT@768503|Cytophagia 976|Bacteroidetes J Domain of unknown function (DUF4202) - - - - - - - - - - - - DUF4202 HSJS1_k127_498274_1 1232443.BAIA02000155_gene1758 2.691e-28 119.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia 186801|Clostridia F Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease HSJS1_k127_499292_0 596154.Alide2_4309 3.652e-124 409.0 COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,2VPAP@28216|Betaproteobacteria,4AFM7@80864|Comamonadaceae 28216|Betaproteobacteria L Insertion element 4 transposase N-terminal - - - - - - - - - - - - DDE_Tnp_1,Nterm_IS4 HSJS1_k127_499292_1 113395.AXAI01000001_gene3403 0.0001112 51.0 COG3620@1|root,COG3620@2|Bacteria,1N84U@1224|Proteobacteria,2TWPS@28211|Alphaproteobacteria,3JZE2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_3,HTH_31 HSJS1_k127_504700_1 156889.Mmc1_3231 2.883e-74 269.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race HSJS1_k127_504700_3 1121430.JMLG01000002_gene1042 2.862e-09 68.0 COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,266Z7@186807|Peptococcaceae 186801|Clostridia S Sporulation and spore germination - - - ko:K06298 - - - - ko00000 - - - Germane HSJS1_k127_504700_2 671143.DAMO_1836 2.915e-46 192.0 COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria 2|Bacteria M Ami_3 amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 HSJS1_k127_504700_4 591157.SSLG_03355 8.445e-05 55.0 COG0346@1|root,COG0346@2|Bacteria,2IHZH@201174|Actinobacteria 201174|Actinobacteria E glyoxalase bleomycin resistance protein dioxygenase gloA - - - - - - - - - - - Glyoxalase HSJS1_k127_504700_0 1123508.JH636446_gene6264 8.897e-132 451.0 COG0823@1|root,COG1262@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity dap2 - 2.7.11.1,3.4.19.1 ko:K01303,ko:K12132 - - - - ko00000,ko01000,ko01001,ko01002 - - - DUF1566,FGE-sulfatase,PD40,Peptidase_S9 HSJS1_k127_506732_1 573370.DMR_06370 7.913e-36 140.0 COG2050@1|root,COG2050@2|Bacteria,1N1PP@1224|Proteobacteria,42TRH@68525|delta/epsilon subdivisions,2WQF9@28221|Deltaproteobacteria,2MC68@213115|Desulfovibrionales 28221|Deltaproteobacteria Q PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT HSJS1_k127_506732_0 926550.CLDAP_37030 3.39e-165 533.0 COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi 200795|Chloroflexi EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HSJS1_k127_507150_2 448385.sce0381 2.589e-08 64.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_507150_1 1121920.AUAU01000004_gene809 1.407e-115 390.0 COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria 57723|Acidobacteria E peptidase M24B X-Pro dipeptidase aminopeptidase domain protein - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 HSJS1_k127_507150_0 391625.PPSIR1_39705 1.092e-151 501.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42V54@68525|delta/epsilon subdivisions,2WSDI@28221|Deltaproteobacteria,2Z0J9@29|Myxococcales 28221|Deltaproteobacteria BQ Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl HSJS1_k127_508369_0 1267535.KB906767_gene5001 4.759e-49 198.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Cu-binding_MopE,Sulfatase HSJS1_k127_508369_1 1131814.JAFO01000001_gene1847 5.67e-36 151.0 COG1216@1|root,COG2120@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2120@2|Bacteria,COG2227@2|Bacteria,1PHP0@1224|Proteobacteria,2VDUQ@28211|Alphaproteobacteria,3F23E@335928|Xanthobacteraceae 28211|Alphaproteobacteria H GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L HSJS1_k127_518352_5 452637.Oter_2932 9.953e-05 48.0 COG3118@1|root,COG3118@2|Bacteria 2|Bacteria O belongs to the thioredoxin family ybbN GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin HSJS1_k127_518352_2 1340493.JNIF01000004_gene177 7.065e-13 83.0 COG1657@1|root,COG3391@1|root,COG1657@2|Bacteria,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K14647,ko:K21449 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko02000,ko03110 1.B.40.2 - - - HSJS1_k127_518352_3 111780.Sta7437_4231 4.885e-12 80.0 COG0823@1|root,COG0823@2|Bacteria,1GJ0J@1117|Cyanobacteria,3VIZ2@52604|Pleurocapsales 1117|Cyanobacteria QU calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - CBM_6,SdrD_B HSJS1_k127_518352_1 1120953.AUBH01000004_gene2977 1.791e-29 137.0 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_518352_6 1120953.AUBH01000004_gene2976 0.0004732 49.0 2BN4A@1|root,32GR8@2|Bacteria,1RHQ4@1224|Proteobacteria,1S86P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_518352_0 67352.JODS01000002_gene1609 1.087e-75 261.0 COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria 201174|Actinobacteria S Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine egtD - 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 HSJS1_k127_523544_4 713586.KB900536_gene2501 1.542e-24 107.0 COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,1RNUW@1236|Gammaproteobacteria,1WVWK@135613|Chromatiales 135613|Chromatiales S Putative transposase, YhgA-like - - - - - - - - - - - - DUF4351,Transposase_31 HSJS1_k127_523544_5 1255043.TVNIR_0026 8.97e-24 105.0 COG1669@1|root,COG1669@2|Bacteria,1NMHI@1224|Proteobacteria 1224|Proteobacteria S Nucleotidyltransferase domain - - - - - - - - - - - - NTP_transf_2 HSJS1_k127_523544_1 227086.JGI_V11_49680 8.723e-93 336.0 COG0402@1|root,KOG3968@2759|Eukaryota 2759|Eukaryota F imidazolonepropionase activity - - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1,M20_dimer,Peptidase_M20 HSJS1_k127_523544_2 1510531.JQJJ01000009_gene1097 7.787e-70 252.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,3JTX1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Peptidase dimerisation domain - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 HSJS1_k127_523544_0 743836.AYNA01000056_gene170 3.835e-178 574.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,36ZVX@31993|Methylocystaceae 28211|Alphaproteobacteria C Domain of unknown function (DUF4070) - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM HSJS1_k127_523544_3 215803.DB30_3073 4.651e-36 140.0 COG0726@1|root,COG4319@1|root,COG0726@2|Bacteria,COG4319@2|Bacteria,1RFCG@1224|Proteobacteria,43BYQ@68525|delta/epsilon subdivisions,2X79K@28221|Deltaproteobacteria,2Z21H@29|Myxococcales 28221|Deltaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 HSJS1_k127_525303_2 1122143.AUEG01000002_gene685 5.384e-10 63.0 COG0653@1|root,COG0653@2|Bacteria,1UNSI@1239|Firmicutes,4IUNT@91061|Bacilli,27GE9@186828|Carnobacteriaceae 91061|Bacilli U SEC-C motif - - - - - - - - - - - - SEC-C HSJS1_k127_525303_0 530564.Psta_2542 9.455e-99 356.0 COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes 203682|Planctomycetes S PQQ-like domain - - - - - - - - - - - - PQQ_2 HSJS1_k127_525303_1 857087.Metme_2701 5.478e-87 324.0 COG1858@1|root,COG1858@2|Bacteria,1RC4D@1224|Proteobacteria,1SJKT@1236|Gammaproteobacteria,1XFYK@135618|Methylococcales 135618|Methylococcales C cytochrome C peroxidase - - - - - - - - - - - - - HSJS1_k127_528245_2 1499967.BAYZ01000115_gene2923 1.904e-27 119.0 COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria 2|Bacteria GM ATPases associated with a variety of cellular activities rfbB - 3.6.3.38,3.6.3.40 ko:K01990,ko:K09689,ko:K09691,ko:K09693 ko02010,map02010 M00249,M00250,M00251,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103,3.A.1.104 - - ABC_tran,Wzt_C HSJS1_k127_528245_3 1047013.AQSP01000124_gene2660 1.166e-09 68.0 COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NR7I@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - ko:K20543 - - - - ko00000,ko02000 1.B.55.3 - - BCSC_C,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 HSJS1_k127_528245_0 306281.AJLK01000019_gene3719 1.008e-49 186.0 COG2947@1|root,COG2947@2|Bacteria,1G5R2@1117|Cyanobacteria,1JIMG@1189|Stigonemataceae 1117|Cyanobacteria S EVE domain - - - - - - - - - - - - EVE HSJS1_k127_528245_1 1227484.C471_01985 6.756e-30 130.0 COG3119@1|root,arCOG02788@2157|Archaea,2Y8G6@28890|Euryarchaeota,23TA6@183963|Halobacteria 183963|Halobacteria P COG3119 Arylsulfatase A and related enzymes - - - ko:K01138 - - - - ko00000,ko01000 - - - Sulfatase HSJS1_k127_529142_2 1123368.AUIS01000024_gene971 7.56e-10 68.0 COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria 2|Bacteria DZ guanyl-nucleotide exchange factor activity - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CarboxypepD_reg,PKD,PQQ_2,RCC1_2,SBBP HSJS1_k127_529142_1 671143.DAMO_1513 3.45e-23 117.0 COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria 2|Bacteria L Protein of unknown function (DUF3105) - - - - - - - - - - - - DDE_Tnp_ISAZ013,DUF3105,HTH_Tnp_IS630 HSJS1_k127_529142_0 1379270.AUXF01000007_gene1056 9.315e-86 299.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes 142182|Gemmatimonadetes KQ helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5,Methyltransf_11 HSJS1_k127_531050_2 1125863.JAFN01000001_gene1826 1.331e-67 233.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG HSJS1_k127_531050_3 1161902.HMPREF0378_1568 1.184e-65 226.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WCHH@538999|Clostridiales incertae sedis 186801|Clostridia J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N HSJS1_k127_531050_1 1121920.AUAU01000017_gene1254 1.003e-95 318.0 COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria 57723|Acidobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA - - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 HSJS1_k127_531050_5 632335.Calkr_1559 2.47e-30 129.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,42GM6@68295|Thermoanaerobacterales 186801|Clostridia J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 HSJS1_k127_531050_4 891968.Anamo_0206 7.227e-40 152.0 COG0222@1|root,COG0222@2|Bacteria,3TB80@508458|Synergistetes 508458|Synergistetes J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N HSJS1_k127_531050_0 204669.Acid345_4676 0.0 1221.0 COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia 204432|Acidobacteriia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 HSJS1_k127_535630_1 694427.Palpr_2132 1.707e-18 87.0 COG0641@1|root,COG0641@2|Bacteria 2|Bacteria C radical SAM - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM HSJS1_k127_535630_0 1278073.MYSTI_06006 1.149e-183 597.0 COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2YUBN@29|Myxococcales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM HSJS1_k127_535985_2 620914.JH621248_gene3091 1.474e-65 244.0 COG2866@1|root,COG2866@2|Bacteria,4NPSD@976|Bacteroidetes,1I880@117743|Flavobacteriia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 HSJS1_k127_535985_0 869210.Marky_1959 2.983e-92 314.0 COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - COX15-CtaA,UbiA HSJS1_k127_535985_1 903818.KI912269_gene113 3.58e-90 301.0 COG0058@1|root,COG0058@2|Bacteria,3Y65H@57723|Acidobacteria 57723|Acidobacteria G PFAM glycosyl transferase, family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase HSJS1_k127_538811_1 234267.Acid_7036 1.251e-55 216.0 COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria 57723|Acidobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - ko:K14161 - - - - ko00000,ko03400 - - - IMS HSJS1_k127_538811_4 1254432.SCE1572_38050 3.319e-13 74.0 COG3357@1|root,COG3357@2|Bacteria,1N7JG@1224|Proteobacteria,42VEP@68525|delta/epsilon subdivisions,2WRD7@28221|Deltaproteobacteria,2Z28M@29|Myxococcales 28221|Deltaproteobacteria K transcriptional regulator containing an HTH domain fused to a Zn-ribbon - - - ko:K07743 - - - - ko00000 - - - HTH_5 HSJS1_k127_538811_0 1499967.BAYZ01000195_gene3091 2.774e-63 242.0 COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria 2|Bacteria S Por secretion system C-terminal sorting domain-containing protein - - - - - - - - - - - - Peptidase_S8,Sortilin-Vps10 HSJS1_k127_538811_2 313596.RB2501_11072 4.777e-26 115.0 COG0457@1|root,COG0457@2|Bacteria,4NNWA@976|Bacteroidetes,1I350@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - HSJS1_k127_538811_3 1089550.ATTH01000001_gene463 5.738e-14 73.0 COG0390@1|root,COG0390@2|Bacteria,4PF9U@976|Bacteroidetes,1FKC8@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Uncharacterised protein family (UPF0014) - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 HSJS1_k127_541613_0 1303518.CCALI_01943 7.439e-27 123.0 COG2333@1|root,COG2333@2|Bacteria 2|Bacteria N competence protein COMEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B HSJS1_k127_541613_1 1267533.KB906733_gene3438 1.507e-07 59.0 COG1595@1|root,COG1595@2|Bacteria,3Y8V2@57723|Acidobacteria 57723|Acidobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HSJS1_k127_543015_0 118168.MC7420_2811 4.268e-75 281.0 COG2133@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1G3EW@1117|Cyanobacteria,1HBBU@1150|Oscillatoriales 1117|Cyanobacteria Q G8 - - - - - - - - - - - - G8,HemolysinCabind,Laminin_G_3,PKD HSJS1_k127_543015_1 1122604.JONR01000067_gene4217 2.837e-08 57.0 COG2207@1|root,COG2207@2|Bacteria,1QVRF@1224|Proteobacteria,1SMB9@1236|Gammaproteobacteria,1X4Y8@135614|Xanthomonadales 135614|Xanthomonadales K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 HSJS1_k127_543852_2 945713.IALB_1464 5.532e-09 59.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity luxD - 3.2.1.4,4.2.99.18 ko:K01179,ko:K06889,ko:K10773,ko:K15853 ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko03400 - GH5,GH9 - Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9 HSJS1_k127_543852_1 1408473.JHXO01000005_gene1511 4.365e-34 140.0 COG1335@1|root,COG1335@2|Bacteria 2|Bacteria Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase,MerR_1 HSJS1_k127_543852_0 1519464.HY22_02720 2.168e-38 154.0 COG0546@1|root,COG0546@2|Bacteria,1FDVN@1090|Chlorobi 1090|Chlorobi S PFAM Haloacid dehalogenase domain protein hydrolase - - - - - - - - - - - - HAD_2 HSJS1_k127_558737_8 478741.JAFS01000002_gene474 4.96e-07 55.0 COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia,37FVR@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia J Probable RNA and SrmB- binding site of polymerase A pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 HSJS1_k127_558737_1 1278073.MYSTI_02283 1.497e-99 342.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales 28221|Deltaproteobacteria NU Type II/IV secretion system protein pilT-1 - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE HSJS1_k127_558737_4 1121918.ARWE01000001_gene2297 4.088e-47 177.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria,43SE6@69541|Desulfuromonadales 28221|Deltaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response) lexA - 3.4.21.88 ko:K01356,ko:K03503 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 HSJS1_k127_558737_2 1131269.AQVV01000001_gene1399 3.162e-89 300.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid pksB GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B HSJS1_k127_558737_7 1125863.JAFN01000001_gene1816 3.418e-08 66.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria 28221|Deltaproteobacteria M AsmA-like C-terminal region - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2,DUF748 HSJS1_k127_558737_5 1173028.ANKO01000086_gene4 6.027e-45 174.0 COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales 1117|Cyanobacteria H Belongs to the P-Pant transferase superfamily hetI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS HSJS1_k127_558737_0 926550.CLDAP_39790 1.188e-249 783.0 COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M3A and M3B, thimet oligopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N HSJS1_k127_558737_3 1125971.ASJB01000069_gene384 1.013e-60 218.0 COG1024@1|root,COG1024@2|Bacteria,2IEXB@201174|Actinobacteria,4E3W4@85010|Pseudonocardiales 201174|Actinobacteria I Enoyl-CoA hydratase/isomerase echA3_1 - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 HSJS1_k127_558737_6 1125863.JAFN01000001_gene1108 1.319e-39 150.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WMFY@28221|Deltaproteobacteria 28221|Deltaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE HSJS1_k127_563603_0 1167006.UWK_00877 1.89e-46 191.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL HSJS1_k127_563603_1 1230476.C207_01268 4.779e-22 112.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3JS0Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Asn_synthase,GATase_7 HSJS1_k127_569645_0 1114959.SZMC14600_17555 3.312e-51 184.0 COG3324@1|root,COG3324@2|Bacteria,2IM88@201174|Actinobacteria,4EAPN@85010|Pseudonocardiales 201174|Actinobacteria EGP glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase HSJS1_k127_569645_4 1396141.BATP01000028_gene2329 3.77e-13 80.0 COG1763@1|root,COG1763@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process - - - ko:K03753,ko:K07588 - - - - ko00000,ko01000 - - - - HSJS1_k127_569645_1 1437425.CSEC_2361 2.984e-24 113.0 COG3832@1|root,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity - - - - - - - - - - - - AHSA1 HSJS1_k127_569645_2 749927.AMED_4721 4.167e-24 108.0 COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria,4E7G8@85010|Pseudonocardiales 201174|Actinobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 HSJS1_k127_569645_5 1278073.MYSTI_04964 7.085e-08 64.0 COG3291@1|root,COG3291@2|Bacteria,1ND6P@1224|Proteobacteria,42VGA@68525|delta/epsilon subdivisions,2WRAP@28221|Deltaproteobacteria,2YXV9@29|Myxococcales 28221|Deltaproteobacteria S PKD domain - - - - - - - - - - - - F5_F8_type_C,PKD HSJS1_k127_569645_3 290400.Jann_3635 2.164e-19 89.0 2AEE0@1|root,3148S@2|Bacteria,1PTR9@1224|Proteobacteria,2UY1I@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mannan-binding protein - - - - - - - - - - - - MVL HSJS1_k127_574607_0 313596.RB2501_08740 3.364e-74 259.0 COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,1HWNT@117743|Flavobacteriia 976|Bacteroidetes S RelA SpoT domain protein - - - - - - - - - - - - GTA_TIM HSJS1_k127_574607_1 1532558.JL39_22070 6.149e-19 91.0 2E32Y@1|root,32Y36@2|Bacteria,1N7G2@1224|Proteobacteria,2UH2J@28211|Alphaproteobacteria,4BGF8@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_577415_0 234267.Acid_5749 5.694e-163 545.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 HSJS1_k127_577415_3 395492.Rleg2_0220 1.337e-05 54.0 COG4319@1|root,COG4319@2|Bacteria,1NZK9@1224|Proteobacteria,2UEHY@28211|Alphaproteobacteria,4BEA8@82115|Rhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_3 HSJS1_k127_577415_2 234267.Acid_5749 2.119e-82 308.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 HSJS1_k127_577415_1 234267.Acid_4535 1.139e-117 415.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria 57723|Acidobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - PD40,Pkinase HSJS1_k127_581044_1 1089550.ATTH01000001_gene1831 1.412e-08 60.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_581044_3 1184251.TCELL_0919 0.0004353 51.0 COG5440@1|root,arCOG01713@2157|Archaea,2XQN2@28889|Crenarchaeota 28889|Crenarchaeota S conserved protein (DUF2299) - - - - - - - - - - - - DUF2299 HSJS1_k127_581044_0 338963.Pcar_1901 1.427e-54 210.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,43T8Y@69541|Desulfuromonadales 28221|Deltaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 HSJS1_k127_581044_2 1121405.dsmv_1823 5.153e-06 56.0 COG0463@1|root,COG1215@1|root,COG0463@2|Bacteria,COG1215@2|Bacteria,1RKWQ@1224|Proteobacteria,42SQ4@68525|delta/epsilon subdivisions,2WPWA@28221|Deltaproteobacteria,2MK96@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 HSJS1_k127_581619_0 314285.KT71_12790 1.653e-268 838.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria,1J9EJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 HSJS1_k127_581619_3 1148.1652800 4.832e-12 71.0 2E16Z@1|root,31VE4@2|Bacteria,1G7HJ@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_581619_1 163908.KB235896_gene2675 6.445e-40 153.0 COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HNNT@1161|Nostocales 1117|Cyanobacteria L PFAM HNH endonuclease - - - - - - - - - - - - HNH HSJS1_k127_581619_5 113355.CM001775_gene1250 0.0005623 44.0 2C2YU@1|root,33M8J@2|Bacteria,1GGAY@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - HSJS1_k127_581619_2 1122135.KB893146_gene1589 2.062e-36 141.0 COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,2TS6Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily MA20_39610 - - - - - - - - - - - EamA HSJS1_k127_58489_2 452637.Oter_2321 2.427e-12 81.0 COG0457@1|root,COG0457@2|Bacteria,46U59@74201|Verrucomicrobia 74201|Verrucomicrobia S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 HSJS1_k127_58489_1 1255043.TVNIR_1305 6.567e-33 147.0 COG0457@1|root,COG0457@2|Bacteria 1255043.TVNIR_1305|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - HSJS1_k127_58489_0 335543.Sfum_1617 1.589e-171 557.0 COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_58489_3 1047013.AQSP01000131_gene1841 1.22e-05 50.0 COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria 2|Bacteria P COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_585224_0 926569.ANT_10660 1.064e-302 938.0 COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi 200795|Chloroflexi J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 HSJS1_k127_585224_1 251221.35211933 9.304e-48 177.0 COG1959@1|root,COG1959@2|Bacteria 2|Bacteria K 2 iron, 2 sulfur cluster binding cymR - - - - - - - - - - - Rrf2 HSJS1_k127_586469_2 1125971.ASJB01000069_gene356 1.216e-16 89.0 2C4AD@1|root,337IV@2|Bacteria,2H86S@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - HSJS1_k127_586469_0 1242864.D187_002446 5.739e-64 235.0 2C4AC@1|root,30014@2|Bacteria,1NW5K@1224|Proteobacteria,43DT1@68525|delta/epsilon subdivisions,2X8VB@28221|Deltaproteobacteria,2Z0JE@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_586469_1 1535422.ND16A_3545 1.04e-62 235.0 COG0308@1|root,COG0308@2|Bacteria,1R30F@1224|Proteobacteria,1T60S@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminopeptidase N - - - - - - - - - - - - - HSJS1_k127_586928_0 1499967.BAYZ01000026_gene1569 1.452e-157 504.0 COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria 2|Bacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 HSJS1_k127_586928_7 649638.Trad_2953 1.431e-15 83.0 COG0071@1|root,COG0071@2|Bacteria,1WKFR@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 HSJS1_k127_586928_6 224324.aq_702 1.489e-30 130.0 COG0789@1|root,COG0789@2|Bacteria,2G4AP@200783|Aquificae 200783|Aquificae K helix_turn_helix, mercury resistance - - - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 HSJS1_k127_586928_8 697282.Mettu_3520 1.044e-11 67.0 2DPTZ@1|root,333CW@2|Bacteria,1NE58@1224|Proteobacteria,1SG82@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_586928_5 1047013.AQSP01000077_gene2270 5.849e-37 152.0 COG1484@1|root,COG1484@2|Bacteria,2NQ23@2323|unclassified Bacteria 2|Bacteria L IstB-like ATP binding protein dnaC - 3.4.21.53 ko:K02315,ko:K04076 - - - - ko00000,ko01000,ko01002,ko03032 - - - AAA,IstB_IS21,Lon_C HSJS1_k127_586928_3 1121920.AUAU01000015_gene1127 1.251e-54 220.0 COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria 57723|Acidobacteria D Stage II sporulation protein - - - ko:K06381 - - - - ko00000 - - - SPOR,SpoIID HSJS1_k127_586928_4 1121472.AQWN01000008_gene1990 7.66e-47 176.0 COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,261W1@186807|Peptococcaceae 186801|Clostridia G PFAM Ribose galactose isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB HSJS1_k127_586928_2 324602.Caur_0701 5.837e-74 259.0 COG0274@1|root,COG0274@2|Bacteria,2G7HC@200795|Chloroflexi,375WJ@32061|Chloroflexia 32061|Chloroflexia H Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC HSJS1_k127_586928_1 1173029.JH980292_gene4046 4.315e-87 293.0 COG4577@1|root,COG4577@2|Bacteria,1G0GA@1117|Cyanobacteria,1H73J@1150|Oscillatoriales 1117|Cyanobacteria CQ PFAM BMC domain - - - - - - - - - - - - BMC HSJS1_k127_587789_4 1108045.GORHZ_121_00120 7.298e-06 50.0 2BT89@1|root,32NDN@2|Bacteria,2HDWZ@201174|Actinobacteria 201174|Actinobacteria S Ribbon-helix-helix protein, copG family - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - - - - - - - - - - RHH_1 HSJS1_k127_587789_0 644282.Deba_3298 1.537e-155 529.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc HSJS1_k127_587789_1 335543.Sfum_2381 1.527e-52 205.0 COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria 1224|Proteobacteria S PFAM Peptidase M48 - - - - - - - - - - - - Peptidase_M48 HSJS1_k127_587789_3 1304872.JAGC01000009_gene116 1.687e-09 67.0 COG3807@1|root,COG3807@2|Bacteria,1N5AB@1224|Proteobacteria,42URU@68525|delta/epsilon subdivisions,2WQYJ@28221|Deltaproteobacteria,2MBA2@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacterial SH3 domain homologues - - - - - - - - - - - - SH3_3 HSJS1_k127_587789_2 102125.Xen7305DRAFT_00014460 6.486e-23 114.0 COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,3VKZ9@52604|Pleurocapsales 1117|Cyanobacteria Q Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - DUF4347,FG-GAP,HemolysinCabind HSJS1_k127_590875_2 378806.STAUR_7258 1.399e-46 194.0 297NQ@1|root,2ZUVN@2|Bacteria,1N1JM@1224|Proteobacteria,43EYZ@68525|delta/epsilon subdivisions,2X2P1@28221|Deltaproteobacteria,2YU8E@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_590875_3 631454.N177_1227 1.864e-20 108.0 COG2159@1|root,COG2159@2|Bacteria,1NAC7@1224|Proteobacteria 1224|Proteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 HSJS1_k127_590875_0 869210.Marky_1233 1.146e-185 595.0 COG1086@1|root,COG1086@2|Bacteria 2|Bacteria GM Polysaccharide biosynthesis protein - - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD HSJS1_k127_590875_1 471854.Dfer_2714 3.902e-54 196.0 COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase family M20 M25 M40 - - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 HSJS1_k127_592442_4 502025.Hoch_4147 3.379e-114 373.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 HSJS1_k127_592442_3 1187851.A33M_3733 1.196e-122 407.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TSZ0@28211|Alphaproteobacteria,3FDRD@34008|Rhodovulum 28211|Alphaproteobacteria F Amidohydrolase family - - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 HSJS1_k127_592442_8 1267533.KB906734_gene3814 1.379e-53 197.0 COG5649@1|root,COG5649@2|Bacteria,3Y4QH@57723|Acidobacteria 57723|Acidobacteria S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 HSJS1_k127_592442_1 1187851.A33M_3732 4.453e-211 668.0 COG0031@1|root,COG0031@2|Bacteria,1QQKZ@1224|Proteobacteria,2TUZQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme - - - - - - - - - - - - PALP HSJS1_k127_592442_2 196162.Noca_1628 5.134e-128 442.0 COG0498@1|root,COG0498@2|Bacteria,2IH7W@201174|Actinobacteria 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme - - - - - - - - - - - - PALP HSJS1_k127_592442_14 644966.Tmar_2017 2.326e-18 98.0 COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,25DGT@186801|Clostridia 186801|Clostridia H PFAM Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 HSJS1_k127_592442_9 1125863.JAFN01000001_gene527 1.341e-45 192.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Lipid A biosynthesis acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans HSJS1_k127_592442_11 290397.Adeh_2613 1.688e-41 167.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK HSJS1_k127_592442_7 1249627.D779_1008 2.209e-76 274.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales 135613|Chromatiales M PFAM Three-deoxy-D-manno-octulosonic-acid transferase - - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N,Kdo HSJS1_k127_592442_13 1379698.RBG1_1C00001G1702 1.326e-22 106.0 COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 HSJS1_k127_592442_6 338966.Ppro_2421 1.801e-81 287.0 COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,42SJG@68525|delta/epsilon subdivisions,2WP9K@28221|Deltaproteobacteria,43T1M@69541|Desulfuromonadales 28221|Deltaproteobacteria U Type II secretion system (T2SS), protein F pulF - - ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSF HSJS1_k127_592442_0 204669.Acid345_1576 7.487e-223 707.0 COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia 204432|Acidobacteriia NU PFAM Type II secretion system protein E - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N HSJS1_k127_592442_16 234267.Acid_0046 9.891e-05 54.0 COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria 57723|Acidobacteria NU Pilus assembly protein - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - - HSJS1_k127_592442_5 1047013.AQSP01000036_gene1385 8.086e-99 357.0 COG4796@1|root,COG4796@2|Bacteria 2|Bacteria U Type ii and iii secretion system protein pulQ - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Cohesin,STN,Secretin,Secretin_N HSJS1_k127_592442_10 1121920.AUAU01000023_gene2434 1.131e-43 165.0 COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria 57723|Acidobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl HSJS1_k127_592442_12 269799.Gmet_1857 3.038e-28 128.0 COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,42ZXF@68525|delta/epsilon subdivisions,2WV6V@28221|Deltaproteobacteria,43UYQ@69541|Desulfuromonadales 28221|Deltaproteobacteria U Pfam:N_methyl_2 oxpG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl HSJS1_k127_592442_15 1047013.AQSP01000085_gene1984 2.896e-17 93.0 COG2165@1|root,COG2165@2|Bacteria 2|Bacteria NU general secretion pathway protein - - - ko:K02456,ko:K02650 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - N_methyl,Pilin_GH,Pilin_PilA HSJS1_k127_596448_1 1196835.A458_02020 4.258e-33 138.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1Z1MG@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD HSJS1_k127_596448_0 1089547.KB913013_gene2262 1.899e-130 449.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 HSJS1_k127_597435_1 234267.Acid_4169 4.407e-145 482.0 COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria 57723|Acidobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c HSJS1_k127_597435_0 1340493.JNIF01000003_gene4408 2.254e-193 614.0 COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria 57723|Acidobacteria T Response regulator receiver - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_597435_5 234267.Acid_6478 1.377e-105 354.0 COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria 57723|Acidobacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran HSJS1_k127_597435_4 1267535.KB906767_gene632 8.767e-109 357.0 COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia 204432|Acidobacteriia V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_597435_2 452637.Oter_1901 2.485e-127 420.0 COG0845@1|root,COG0845@2|Bacteria,46UK7@74201|Verrucomicrobia 74201|Verrucomicrobia M HlyD family secretion protein - - - - - - - - - - - - - HSJS1_k127_597435_3 1123371.ATXH01000001_gene1200 1.132e-124 422.0 COG3276@1|root,COG3276@2|Bacteria,2GH20@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Elongation factor SelB, winged helix - - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 HSJS1_k127_597435_6 3055.EDP07571 0.0003189 45.0 COG1610@1|root,2S76A@2759|Eukaryota,382HE@33090|Viridiplantae 33090|Viridiplantae S Yqey-like protein - - - - - - - - - - - - YqeY HSJS1_k127_601409_1 1232410.KI421412_gene109 5.885e-89 316.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,43TD6@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase HSJS1_k127_601409_2 1267533.KB906741_gene637 2.216e-51 196.0 COG2890@1|root,COG2890@2|Bacteria,3Y4KU@57723|Acidobacteria,2JJCF@204432|Acidobacteriia 204432|Acidobacteriia J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC - 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS HSJS1_k127_601409_3 404589.Anae109_0398 3.133e-31 144.0 COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales 28221|Deltaproteobacteria M Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg HSJS1_k127_601409_0 204669.Acid345_4472 1.031e-136 447.0 COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria,2JHYH@204432|Acidobacteriia 204432|Acidobacteriia J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 HSJS1_k127_601409_4 1209989.TepiRe1_2280 3.15e-14 72.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,42H2T@68295|Thermoanaerobacterales 186801|Clostridia J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 HSJS1_k127_605097_3 1129374.AJE_07800 4.397e-18 86.0 2E5P1@1|root,330DP@2|Bacteria,1N794@1224|Proteobacteria,1SD5J@1236|Gammaproteobacteria,468RV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 HSJS1_k127_605097_2 880072.Desac_2480 2.902e-19 88.0 2BWKX@1|root,33G81@2|Bacteria,1NK6V@1224|Proteobacteria,42XE2@68525|delta/epsilon subdivisions,2WT0U@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_605097_1 1125863.JAFN01000001_gene1902 7.318e-29 118.0 COG2026@1|root,COG2026@2|Bacteria 2|Bacteria DJ nuclease activity - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin HSJS1_k127_605097_0 118163.Ple7327_3590 4.408e-79 270.0 COG0452@1|root,COG0452@2|Bacteria,1G2DG@1117|Cyanobacteria,3VJEM@52604|Pleurocapsales 1117|Cyanobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein HSJS1_k127_6060_2 903818.KI912268_gene709 1.037e-79 270.0 COG1100@1|root,COG1100@2|Bacteria 2|Bacteria S GTP binding - - - ko:K06883 - - - - ko00000 - - - DUF697,MMR_HSR1 HSJS1_k127_6060_10 367299.JOEE01000001_gene1988 2.636e-20 102.0 COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria,4FE81@85021|Intrasporangiaceae 201174|Actinobacteria S Coenzyme F420-dependent NADP oxidoreductase - - - - - - - - - - - - DUF2520,Rossmann-like HSJS1_k127_6060_3 935567.JAES01000027_gene1280 4.109e-74 262.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1X44P@135614|Xanthomonadales 135614|Xanthomonadales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg HSJS1_k127_6060_6 1267533.KB906733_gene3314 4.436e-31 131.0 COG0576@1|root,COG0576@2|Bacteria,3Y7HM@57723|Acidobacteria,2JMQ2@204432|Acidobacteriia 204432|Acidobacteriia O GrpE - - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE HSJS1_k127_6060_0 648757.Rvan_2314 1.632e-226 717.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,3N6KP@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 HSJS1_k127_6060_1 1121918.ARWE01000001_gene3463 7.693e-116 385.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales 28221|Deltaproteobacteria O DnaJ central domain dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG HSJS1_k127_6060_5 69042.WH5701_15021 3.722e-31 135.0 COG2264@1|root,COG2264@2|Bacteria,1G0G1@1117|Cyanobacteria,1GZDT@1129|Synechococcus 1117|Cyanobacteria J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA HSJS1_k127_6060_8 234267.Acid_0955 6.706e-25 113.0 COG1385@1|root,COG1385@2|Bacteria,3Y3XJ@57723|Acidobacteria 57723|Acidobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA HSJS1_k127_6060_9 351627.Csac_0182 6.985e-22 104.0 2E25X@1|root,32XCM@2|Bacteria,1UJJ7@1239|Firmicutes,25F48@186801|Clostridia,42J75@68295|Thermoanaerobacterales 186801|Clostridia S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii HSJS1_k127_6060_11 1347369.CCAD010000041_gene736 1.216e-12 80.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,1ZFNB@1386|Bacillus 91061|Bacilli D Cell division initiation protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA HSJS1_k127_6060_4 518766.Rmar_2168 1.571e-55 203.0 COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1FJ6H@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N HSJS1_k127_6060_7 204669.Acid345_0088 3.179e-29 121.0 COG0328@1|root,COG0328@2|Bacteria,3Y4EY@57723|Acidobacteria,2JJ1U@204432|Acidobacteriia 204432|Acidobacteriia L Reverse transcriptase-like - - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 HSJS1_k127_609721_0 1121456.ATVA01000013_gene1018 1.466e-182 593.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2M8X8@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 51 pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase HSJS1_k127_611301_1 318167.Sfri_0463 7.388e-16 87.0 COG0526@1|root,COG0526@2|Bacteria,1NAHI@1224|Proteobacteria,1SCND@1236|Gammaproteobacteria,2QB1H@267890|Shewanellaceae 1236|Gammaproteobacteria CO Thioredoxin - - - - - - - - - - - - Thioredoxin,Thioredoxin_9 HSJS1_k127_611301_0 867903.ThesuDRAFT_01401 1.097e-137 451.0 COG0348@1|root,COG0348@2|Bacteria,1U9JQ@1239|Firmicutes,24ADI@186801|Clostridia 186801|Clostridia C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_5 HSJS1_k127_613797_9 498761.HM1_2261 3.016e-10 63.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia 186801|Clostridia H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf HSJS1_k127_613797_4 278963.ATWD01000001_gene1951 9.69e-30 130.0 COG4589@1|root,COG4589@2|Bacteria,3Y4VA@57723|Acidobacteria,2JJIU@204432|Acidobacteriia 204432|Acidobacteriia S Belongs to the CDS family - - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 HSJS1_k127_613797_0 868864.Dester_1526 2.194e-84 295.0 COG0750@1|root,COG0750@2|Bacteria,2G3QY@200783|Aquificae 200783|Aquificae M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 HSJS1_k127_613797_7 644283.Micau_4509 5.371e-14 86.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4D8KT@85008|Micromonosporales 201174|Actinobacteria KLT serine threonine protein kinase pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase HSJS1_k127_613797_1 234267.Acid_3191 2.555e-60 227.0 COG0036@1|root,COG0036@2|Bacteria,3Y3YN@57723|Acidobacteria 57723|Acidobacteria G Belongs to the ribulose-phosphate 3-epimerase family - - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim HSJS1_k127_613797_6 1123376.AUIU01000012_gene1351 5.42e-20 105.0 COG4105@1|root,COG4105@2|Bacteria,3J0UU@40117|Nitrospirae 40117|Nitrospirae S Tetratricopeptide repeat - - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO HSJS1_k127_613797_5 1125863.JAFN01000001_gene3051 1.219e-23 111.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6 HSJS1_k127_613797_3 1121920.AUAU01000014_gene2832 6.099e-32 140.0 COG1652@1|root,COG1652@2|Bacteria 2|Bacteria S positive regulation of growth rate - - - - - - - - - - - - CW_binding_2,LysM HSJS1_k127_613797_10 266264.Rmet_0588 0.0008778 50.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K2CD@119060|Burkholderiaceae 28216|Betaproteobacteria T response regulator dctD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K10126,ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 M00504 - - ko00000,ko00001,ko00002,ko02022,ko03000 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_613797_2 1125863.JAFN01000001_gene3191 4.399e-34 141.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Lytic transglycosylase catalytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - DUF4124,SLT HSJS1_k127_613797_8 1158338.JNLJ01000001_gene932 3.123e-11 66.0 COG1826@1|root,COG1826@2|Bacteria,2G4BU@200783|Aquificae 200783|Aquificae U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 HSJS1_k127_615809_0 1183438.GKIL_4354 4.059e-112 391.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_615809_1 665942.HMPREF1022_02023 1.072e-86 303.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales 28221|Deltaproteobacteria E TIGRFAM asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 HSJS1_k127_618453_1 502025.Hoch_2041 2.06e-69 250.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria 68525|delta/epsilon subdivisions KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase HSJS1_k127_618453_0 756272.Plabr_2643 8.224e-164 524.0 COG0189@1|root,COG0490@1|root,COG0189@2|Bacteria,COG0490@2|Bacteria,2IYT1@203682|Planctomycetes 203682|Planctomycetes HJ COG0189 Glutathione synthase Ribosomal protein S6 modification - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK,TrkA_C HSJS1_k127_618453_2 1278073.MYSTI_05825 4.737e-26 116.0 COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - HSJS1_k127_619104_0 1283300.ATXB01000001_gene1787 2.362e-74 259.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XE1F@135618|Methylococcales 135618|Methylococcales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS HSJS1_k127_619104_1 1047013.AQSP01000131_gene1840 1.035e-36 157.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria 2|Bacteria T Tetratricopeptide repeat - - - - - - - - - - - - Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 HSJS1_k127_621589_1 314271.RB2654_06724 5.01e-31 138.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2 HSJS1_k127_621589_0 1267533.KB906733_gene3362 3.766e-81 293.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia 204432|Acidobacteriia K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Trans_reg_C HSJS1_k127_639537_0 880073.Calab_3321 0.0 1255.0 COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria 2|Bacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family czcA - - ko:K07787,ko:K15726 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 - iAF987.Gmet_1547 ACR_tran HSJS1_k127_639537_1 880073.Calab_3322 8.146e-116 401.0 COG0845@1|root,COG0845@2|Bacteria,2NP3Y@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HlyD_D23 HSJS1_k127_639537_2 382464.ABSI01000014_gene1483 1.703e-42 173.0 COG1538@1|root,COG1538@2|Bacteria,46WHQ@74201|Verrucomicrobia,2IW13@203494|Verrucomicrobiae 203494|Verrucomicrobiae MU Outer membrane efflux protein - - - - - - - - - - - - OEP HSJS1_k127_639537_3 247490.KSU1_B0440 3.35e-06 59.0 2AVTU@1|root,31MME@2|Bacteria,2J2ZG@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - HSJS1_k127_644695_1 1254432.SCE1572_18585 2.257e-11 67.0 COG4118@1|root,COG4118@2|Bacteria 2|Bacteria D positive regulation of growth - - - ko:K18829 - - - - ko00000,ko02048 - - - PhdYeFM_antitox HSJS1_k127_644695_0 1125863.JAFN01000001_gene2889 7.423e-142 464.0 COG1373@1|root,COG1373@2|Bacteria,1R3UA@1224|Proteobacteria,42N3U@68525|delta/epsilon subdivisions,2WJ04@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 HSJS1_k127_645313_1 1132509.C447_10620 7.569e-19 94.0 arCOG08948@1|root,arCOG11838@1|root,arCOG08948@2157|Archaea,arCOG11838@2157|Archaea,2Y03W@28890|Euryarchaeota 28890|Euryarchaeota S CHRD domain - - - - - - - - - - - - CHRD,Ferritin_2 HSJS1_k127_645313_0 215803.DB30_7235 4.377e-177 586.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales 1224|Proteobacteria V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD HSJS1_k127_645313_2 742726.HMPREF9448_01901 0.000838 46.0 28TKX@1|root,2ZFUJ@2|Bacteria,4NM89@976|Bacteroidetes,2FN5Z@200643|Bacteroidia,231JD@171551|Porphyromonadaceae 976|Bacteroidetes S Psort location Cytoplasmic, score - - - - - - - - - - - - - HSJS1_k127_648934_1 1254432.SCE1572_00290 2.258e-35 138.0 COG0517@1|root,COG0517@2|Bacteria,1QZT1@1224|Proteobacteria,43CN4@68525|delta/epsilon subdivisions,2X7VC@28221|Deltaproteobacteria,2Z3IG@29|Myxococcales 28221|Deltaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS HSJS1_k127_648934_0 935836.JAEL01000119_gene5435 1.869e-40 151.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus 91061|Bacilli E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans HSJS1_k127_651123_3 345341.KUTG_08700 1.465e-29 118.0 COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria,4E08E@85010|Pseudonocardiales 201174|Actinobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase HSJS1_k127_651123_0 1449357.JQLK01000001_gene890 5.491e-52 192.0 COG4636@1|root,COG4636@2|Bacteria,1WJWU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Putative restriction endonuclease - - - - - - - - - - - - Uma2 HSJS1_k127_651123_2 1242864.D187_009621 4.659e-44 173.0 COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales 28221|Deltaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin HSJS1_k127_651123_1 1120953.AUBH01000006_gene2643 5.643e-49 186.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,46AI8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 HSJS1_k127_659041_0 391625.PPSIR1_35412 1.312e-74 259.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2WN0R@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA HSJS1_k127_659041_2 439235.Dalk_1867 2.076e-12 81.0 COG0784@1|root,COG2202@1|root,COG4191@1|root,COG4936@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2MIC0@213118|Desulfobacterales 28221|Deltaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg HSJS1_k127_659041_1 1173025.GEI7407_1780 2.259e-51 208.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales 1117|Cyanobacteria U Tetratricopeptide repeat - - - - - - - - - - - - CHAT,TPR_12,TPR_7 HSJS1_k127_667236_1 1047013.AQSP01000106_gene1771 1.044e-12 73.0 COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA2 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SecA_DEAD,SecA_PP_bind,SecA_SW HSJS1_k127_667236_0 502025.Hoch_5119 6.242e-231 731.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales 28221|Deltaproteobacteria C Sulfite reductase - - 1.7.7.1,1.8.1.2,1.8.7.1 ko:K00366,ko:K00381,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00531 R00790,R00858,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr HSJS1_k127_669448_0 1254432.SCE1572_34120 1.954e-121 419.0 COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,43823@68525|delta/epsilon subdivisions,2X3C5@28221|Deltaproteobacteria,2YVD0@29|Myxococcales 28221|Deltaproteobacteria S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 HSJS1_k127_669448_1 211165.AJLN01000137_gene1503 1.375e-99 339.0 COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1JI27@1189|Stigonemataceae 1117|Cyanobacteria J translation release factor activity - - - - - - - - - - - - - HSJS1_k127_669448_2 584708.Apau_1022 3.81e-08 61.0 COG1610@1|root,COG1610@2|Bacteria,3TB54@508458|Synergistetes 508458|Synergistetes S YqeY-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY HSJS1_k127_673077_0 204669.Acid345_2676 1.871e-104 358.0 COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia 204432|Acidobacteriia M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 HSJS1_k127_673077_2 234267.Acid_2827 1.377e-13 78.0 COG1826@1|root,COG1826@2|Bacteria,3Y5TY@57723|Acidobacteria 57723|Acidobacteria U mttA/Hcf106 family - - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 HSJS1_k127_673077_1 204669.Acid345_2680 7.43e-65 233.0 COG0805@1|root,COG0805@2|Bacteria,3Y3UC@57723|Acidobacteria,2JISU@204432|Acidobacteriia 204432|Acidobacteriia U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC HSJS1_k127_675865_0 1337936.IJ00_01670 7.826e-84 302.0 COG1680@1|root,COG1680@2|Bacteria,1G5Z2@1117|Cyanobacteria,1HIVF@1161|Nostocales 1117|Cyanobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase HSJS1_k127_675865_1 105559.Nwat_1040 5.969e-58 209.0 COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,1X1P9@135613|Chromatiales 135613|Chromatiales K IclR helix-turn-helix domain - - - - - - - - - - - - HTH_24 HSJS1_k127_675865_2 1128421.JAGA01000003_gene3140 3.818e-23 99.0 COG5621@1|root,COG5621@2|Bacteria,2NPFN@2323|unclassified Bacteria 2|Bacteria S Lipocalin-like domain attH - - - - - - - - - - - CrtC,Lipocalin_9 HSJS1_k127_676767_1 1173027.Mic7113_6150 1.151e-28 123.0 COG4067@1|root,COG4067@2|Bacteria,1G6KI@1117|Cyanobacteria,1HBYC@1150|Oscillatoriales 1117|Cyanobacteria O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease HSJS1_k127_676767_0 1192034.CAP_7036 1.152e-80 286.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales 28221|Deltaproteobacteria L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 HSJS1_k127_676767_2 215803.DB30_7168 2.961e-20 104.0 COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales 28221|Deltaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding HSJS1_k127_676767_3 1121019.AUMN01000008_gene3247 1.781e-12 79.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1W7T9@1268|Micrococcaceae 201174|Actinobacteria K Crp Fnr family glxR GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding HSJS1_k127_677654_2 251221.35210648 6.256e-07 61.0 COG2823@1|root,COG2823@2|Bacteria 2|Bacteria S hyperosmotic response - - - ko:K04065 - - - - ko00000 - - - BON HSJS1_k127_677654_0 1120965.AUBV01000001_gene3486 7.969e-84 299.0 COG2866@1|root,COG2866@2|Bacteria,4NGIE@976|Bacteroidetes,47N2M@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 HSJS1_k127_683942_1 909663.KI867150_gene1401 1.311e-17 83.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2MQ52@213462|Syntrophobacterales 28221|Deltaproteobacteria F aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N HSJS1_k127_683942_0 1392501.JIAC01000001_gene1162 2.296e-59 211.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4H3ZG@909932|Negativicutes 909932|Negativicutes F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran HSJS1_k127_683942_2 1123401.JHYQ01000021_gene1062 1.497e-17 90.0 COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Transmembrane exosortase (Exosortase_EpsH) - - - - - - - - - - - - Exosortase_EpsH HSJS1_k127_684056_2 1123242.JH636434_gene5024 4.437e-112 374.0 COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes 203682|Planctomycetes C COG0644 Dehydrogenases (flavoproteins) - - - - - - - - - - - - Trp_halogenase HSJS1_k127_684056_0 314230.DSM3645_18936 8.153e-126 419.0 COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes 203682|Planctomycetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF HSJS1_k127_684056_1 1210884.HG799465_gene11439 1.326e-112 383.0 COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes 203682|Planctomycetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_684056_4 290317.Cpha266_0252 1.262e-25 109.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system - - - - - - - - - - - - ParE_toxin HSJS1_k127_684056_6 525897.Dbac_1114 5.806e-12 74.0 2EPQB@1|root,33HAX@2|Bacteria,1NGGD@1224|Proteobacteria,42XQZ@68525|delta/epsilon subdivisions,2WT07@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Putative addiction module component - - - - - - - - - - - - Unstab_antitox HSJS1_k127_684056_7 1123242.JH636435_gene1430 0.0001259 47.0 COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes 203682|Planctomycetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_684056_5 1156919.QWC_06409 6.981e-17 90.0 COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2VRM6@28216|Betaproteobacteria,3T806@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 HSJS1_k127_684985_1 1242864.D187_003099 6.069e-12 78.0 COG1506@1|root,COG2885@1|root,COG1506@2|Bacteria,COG2885@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales 28221|Deltaproteobacteria E Domain of unknown function (DUF4215) - - - - - - - - - - - - DUF4215 HSJS1_k127_684985_2 1210884.HG799477_gene15460 2.828e-05 54.0 COG2706@1|root,COG3209@1|root,COG2706@2|Bacteria,COG3209@2|Bacteria,2J4YJ@203682|Planctomycetes 203682|Planctomycetes G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS HSJS1_k127_689293_3 1121405.dsmv_3283 3.072e-17 93.0 COG5492@1|root,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - BACON,Big_2,LRR_5,SLH HSJS1_k127_689293_1 1121935.AQXX01000089_gene4656 2.593e-133 428.0 COG0655@1|root,COG0655@2|Bacteria,1N5Q7@1224|Proteobacteria,1RY1K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0655 Multimeric flavodoxin WrbA - - - - - - - - - - - - FMN_red HSJS1_k127_689293_0 1329516.JPST01000019_gene2740 3.604e-202 646.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,27AWD@186824|Thermoactinomycetaceae 91061|Bacilli J GAD domain aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon HSJS1_k127_689293_2 1120973.AQXL01000135_gene1385 4.222e-24 106.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,277Y8@186823|Alicyclobacillaceae 91061|Bacilli J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His HSJS1_k127_693310_0 1089550.ATTH01000001_gene1831 9.494e-133 448.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 HSJS1_k127_697472_0 756272.Plabr_3820 9.048e-135 442.0 COG2931@1|root,COG2931@2|Bacteria,2J53M@203682|Planctomycetes 203682|Planctomycetes C Animal haem peroxidase - - - - - - - - - - - - An_peroxidase HSJS1_k127_697843_1 1177179.A11A3_01717 3.481e-33 130.0 COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1XIAF@135619|Oceanospirillales 135619|Oceanospirillales M Cyclopropane fatty acid synthase and related - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS HSJS1_k127_697843_0 1458275.AZ34_07550 2.813e-85 295.0 COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2VQHY@28216|Betaproteobacteria,4ADH5@80864|Comamonadaceae 28216|Betaproteobacteria S 3-oxo-5-alpha-steroid 4-dehydrogenase - - - - - - - - - - - - DUF1295 HSJS1_k127_697843_2 1517416.IDAT_12800 8.602e-07 63.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,2QF2H@267893|Idiomarinaceae 1236|Gammaproteobacteria M rhs family - - - - - - - - - - - - RHS_repeat HSJS1_k127_708497_3 1242864.D187_001137 1.017e-25 112.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria 28221|Deltaproteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding HSJS1_k127_708497_4 1242864.D187_001136 1.883e-08 65.0 COG0236@1|root,COG0236@2|Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpM - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding,ketoacyl-synt HSJS1_k127_708497_2 68199.JNZO01000014_gene3890 7.379e-54 198.0 COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria 201174|Actinobacteria S Isoprenylcysteine carboxyl methyltransferase srsB - - ko:K16168 - - - - ko00000,ko01008 - - - ICMT HSJS1_k127_708497_0 1144275.COCOR_07209 1.981e-139 451.0 COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales 28221|Deltaproteobacteria Q Chalcone and stilbene synthases, C-terminal domain - - 2.3.1.233 ko:K16167,ko:K19580 - - R10965 RC00004 ko00000,ko01000,ko01008 - - - Chal_sti_synt_C,Chal_sti_synt_N HSJS1_k127_708497_1 391625.PPSIR1_37859 2.079e-55 203.0 COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,42UTP@68525|delta/epsilon subdivisions,2WQM6@28221|Deltaproteobacteria,2YY49@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short HSJS1_k127_718341_0 926550.CLDAP_23610 1.563e-09 70.0 COG1664@1|root,COG3743@1|root,COG1664@2|Bacteria,COG3743@2|Bacteria,2G7EZ@200795|Chloroflexi 200795|Chloroflexi M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin HSJS1_k127_72116_0 1296416.JACB01000042_gene1780 4.736e-25 121.0 COG2304@1|root,COG3591@1|root,COG2304@2|Bacteria,COG3591@2|Bacteria 2|Bacteria E Belongs to the peptidase S1B family - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - Big_2,NB-ARC,PKD,PPC,Sel1,Trypsin,Trypsin_2,VWA,VWA_2 HSJS1_k127_72116_1 1894.JOER01000015_gene7995 2.116e-07 62.0 COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria 201174|Actinobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran HSJS1_k127_724777_0 886293.Sinac_4372 2.054e-176 565.0 COG1861@1|root,COG1861@2|Bacteria,2J3F7@203682|Planctomycetes 203682|Planctomycetes M PFAM Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_4 HSJS1_k127_728084_10 1121439.dsat_1651 2.104e-14 74.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2X69T@28221|Deltaproteobacteria,2MH0A@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 HSJS1_k127_728084_6 754476.Q7A_751 1.512e-37 147.0 2AUKY@1|root,31K9Q@2|Bacteria,1RH1X@1224|Proteobacteria,1SD4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL HSJS1_k127_728084_11 525897.Dbac_3220 6.284e-07 61.0 COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2MD2I@213115|Desulfovibrionales 28221|Deltaproteobacteria S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p HSJS1_k127_728084_9 1340493.JNIF01000003_gene3926 4.776e-22 110.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - - - - - - - - - - Wzy_C HSJS1_k127_728084_2 330214.NIDE3719 4.255e-74 264.0 COG1189@1|root,COG1189@2|Bacteria,3J0MD@40117|Nitrospirae 40117|Nitrospirae J FtsJ-like methyltransferase - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 HSJS1_k127_728084_3 671143.DAMO_0325 3.639e-69 245.0 COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria 2|Bacteria G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 NAD_kinase HSJS1_k127_728084_5 1267533.KB906733_gene3573 4.689e-40 173.0 COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia 204432|Acidobacteriia M TamB, inner membrane protein subunit of TAM complex - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB HSJS1_k127_728084_4 1125863.JAFN01000001_gene506 1.923e-64 252.0 COG4775@1|root,COG4775@2|Bacteria,1RJPJ@1224|Proteobacteria,42TA2@68525|delta/epsilon subdivisions,2WP1H@28221|Deltaproteobacteria 28221|Deltaproteobacteria M surface antigen - - - - - - - - - - - - Bac_surface_Ag,POTRA HSJS1_k127_728084_12 469383.Cwoe_5333 0.000257 53.0 COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4CRCB@84995|Rubrobacteria 84995|Rubrobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - AAA_16,GerE HSJS1_k127_728084_1 289376.THEYE_A0208 2.764e-172 553.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3J0E0@40117|Nitrospirae 40117|Nitrospirae H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 HSJS1_k127_728084_8 357808.RoseRS_0401 3.617e-33 145.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K00786 - - - - ko00000,ko01000 - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 HSJS1_k127_728084_7 671143.DAMO_2458 6.087e-35 137.0 COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 HSJS1_k127_728084_0 234267.Acid_6747 7.773e-188 594.0 COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria 57723|Acidobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 HSJS1_k127_735483_1 1223543.GP2_032_00360 2.82e-38 147.0 2E7G3@1|root,331YZ@2|Bacteria,2IQJZ@201174|Actinobacteria,4GGGF@85026|Gordoniaceae 201174|Actinobacteria - - - - - - - - - - - - - - - HSJS1_k127_735483_2 1348657.M622_16095 7.804e-13 73.0 2EG90@1|root,33A0T@2|Bacteria,1NMR2@1224|Proteobacteria,2W49T@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_735483_0 575540.Isop_3282 1.634e-228 723.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes 203682|Planctomycetes M Tricorn protease C1 domain - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ HSJS1_k127_737979_1 1232410.KI421428_gene1011 7.358e-74 249.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,43S0T@69541|Desulfuromonadales 28221|Deltaproteobacteria F Anaerobic ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD HSJS1_k127_737979_3 1232410.KI421428_gene1012 1.387e-20 91.0 COG1328@1|root,COG1328@2|Bacteria,1NHSP@1224|Proteobacteria,42WV9@68525|delta/epsilon subdivisions,2WSX8@28221|Deltaproteobacteria,43STA@69541|Desulfuromonadales 28221|Deltaproteobacteria F Anaerobic ribonucleoside-triphosphate reductase - - - - - - - - - - - - NRDD HSJS1_k127_737979_0 1232410.KI421428_gene1013 3.961e-105 345.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42QX3@68525|delta/epsilon subdivisions,2WPC7@28221|Deltaproteobacteria,43SFR@69541|Desulfuromonadales 28221|Deltaproteobacteria O 4Fe-4S single cluster domain pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM HSJS1_k127_737979_2 1218074.BAXZ01000024_gene4363 1.604e-31 125.0 2CTS0@1|root,32SU1@2|Bacteria,1N10P@1224|Proteobacteria,2VVCE@28216|Betaproteobacteria,1K9SD@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_740366_1 1487953.JMKF01000025_gene2357 9.811e-85 287.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1H72I@1150|Oscillatoriales 1117|Cyanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR HSJS1_k127_740366_0 1333523.L593_06205 6.295e-168 558.0 COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria 183963|Halobacteria E COG0531 Amino acid transporters - - - - - - - - - - - - AA_permease,AA_permease_2,Usp HSJS1_k127_740366_4 1121943.KB899993_gene48 8.579e-25 118.0 COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C HSJS1_k127_740366_5 1038858.AXBA01000001_gene3390 2.332e-06 52.0 2F0F2@1|root,33TI4@2|Bacteria,1NU4V@1224|Proteobacteria,2UQKX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_740366_3 1047013.AQSP01000052_gene2599 5.207e-71 265.0 COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria 2|Bacteria CP ABC-2 family transporter protein natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 HSJS1_k127_740366_2 1047013.AQSP01000052_gene2600 5.193e-77 266.0 COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4162) natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 HSJS1_k127_746108_0 1382306.JNIM01000001_gene1023 3.932e-167 540.0 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrA - 1.3.7.9 ko:K04108 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 HSJS1_k127_748182_3 94624.Bpet0867 4.06e-15 83.0 COG2188@1|root,COG2188@2|Bacteria,1MVPT@1224|Proteobacteria,2VVFH@28216|Betaproteobacteria,3T4X2@506|Alcaligenaceae 28216|Betaproteobacteria K transcriptional - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA HSJS1_k127_748182_0 326427.Cagg_3090 1.9e-322 996.0 COG0146@1|root,COG0146@2|Bacteria,2GAKD@200795|Chloroflexi,376MX@32061|Chloroflexia 32061|Chloroflexia EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B HSJS1_k127_748182_1 867845.KI911784_gene411 8.186e-290 911.0 COG0145@1|root,COG0145@2|Bacteria 2|Bacteria EQ ligase activity hyuA - 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B HSJS1_k127_748182_2 1265313.HRUBRA_00839 7.049e-29 125.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria 1224|Proteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec HSJS1_k127_750188_0 935863.AWZR01000001_gene1664 4.537e-175 594.0 COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X52B@135614|Xanthomonadales 135614|Xanthomonadales S Patatin-like phospholipase - - - - - - - - - - - - Patatin HSJS1_k127_769036_2 290397.Adeh_1565 7.325e-157 518.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2YYYV@29|Myxococcales 28221|Deltaproteobacteria P transporter of a GTP-driven Fe(2 ) uptake system - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate HSJS1_k127_769036_9 1089553.Tph_c04540 5.556e-14 86.0 COG1918@1|root,COG1918@2|Bacteria,1VMJD@1239|Firmicutes,24VI7@186801|Clostridia,42HGN@68295|Thermoanaerobacterales 186801|Clostridia P FeoA - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA HSJS1_k127_769036_10 240016.ABIZ01000001_gene4131 3.029e-09 62.0 2DKHS@1|root,309HK@2|Bacteria,46WMT@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - HSJS1_k127_769036_4 370438.PTH_2352 1.468e-99 338.0 28JGA@1|root,2Z9A3@2|Bacteria,1VJ9Q@1239|Firmicutes,24SUJ@186801|Clostridia,264JT@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - HSJS1_k127_769036_8 1089547.KB913014_gene4874 2.89e-42 173.0 COG1538@1|root,COG1538@2|Bacteria,4NI8J@976|Bacteroidetes 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP HSJS1_k127_769036_5 1121035.AUCH01000004_gene327 1.506e-76 273.0 COG0845@1|root,COG0845@2|Bacteria,1QZQZ@1224|Proteobacteria 1224|Proteobacteria M HlyD family secretion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 HSJS1_k127_769036_0 370438.PTH_2380 1.296e-278 874.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,261EJ@186807|Peptococcaceae 186801|Clostridia V NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - - - - - - - - - - ABC_membrane,ABC_tran,Peptidase_C39 HSJS1_k127_769036_1 767817.Desgi_2846 3.119e-230 747.0 COG2274@1|root,COG2274@2|Bacteria,1TRMR@1239|Firmicutes,248Z2@186801|Clostridia,261E8@186807|Peptococcaceae 186801|Clostridia P NHLM bacteriocin system ABC transporter, ATP-binding protein - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran HSJS1_k127_769036_6 1173027.Mic7113_4412 5.476e-49 180.0 COG2905@1|root,COG2905@2|Bacteria,1GQ2G@1117|Cyanobacteria,1HI0B@1150|Oscillatoriales 1117|Cyanobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding HSJS1_k127_769036_7 391625.PPSIR1_29685 1.052e-48 185.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - ko:K08978 - - - - ko00000,ko02000 2.A.7.2 - - EamA HSJS1_k127_769036_3 439235.Dalk_1526 2.572e-151 519.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12 HSJS1_k127_775121_1 880073.Calab_1230 8.735e-124 409.0 COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria 2|Bacteria S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_775121_2 861299.J421_0915 6.354e-79 287.0 COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Insulinase (Peptidase family M16) - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C HSJS1_k127_775121_3 640081.Dsui_1522 8.027e-73 269.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales 28216|Betaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PEGA,Pkinase HSJS1_k127_775121_0 555088.DealDRAFT_2165 2.205e-203 655.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42JHA@68298|Syntrophomonadaceae 186801|Clostridia J elongation factor Tu domain 2 protein fusA2 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 HSJS1_k127_775121_4 765869.BDW_10830 2.17e-06 51.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2MT93@213481|Bdellovibrionales,2WP9P@28221|Deltaproteobacteria 213481|Bdellovibrionales J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 HSJS1_k127_786469_2 1242864.D187_007523 9.999e-39 147.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,4345U@68525|delta/epsilon subdivisions,2X20T@28221|Deltaproteobacteria,2YVEZ@29|Myxococcales 28221|Deltaproteobacteria T PAS domain - - - - - - - - - - - - HATPase_c,PAS HSJS1_k127_786469_1 502025.Hoch_5509 4.64e-64 250.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,43C0B@68525|delta/epsilon subdivisions,2X7B2@28221|Deltaproteobacteria,2Z3EU@29|Myxococcales 28221|Deltaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_786469_0 1123242.JH636435_gene833 7.944e-100 353.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes 203682|Planctomycetes P arylsulfatase A - - - - - - - - - - - - Sulfatase,TPR_16,TPR_19,TPR_2 HSJS1_k127_786811_3 1306174.JODP01000015_gene3987 4.131e-36 144.0 COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria 201174|Actinobacteria S YigZ family yigZ - - - - - - - - - - - DUF1949,UPF0029 HSJS1_k127_786811_0 682795.AciX8_1432 1.106e-117 389.0 COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia 204432|Acidobacteriia M glycosyl transferase group 1 - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 HSJS1_k127_786811_1 518766.Rmar_0672 5.97e-60 219.0 COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1FIXS@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L HSJS1_k127_786811_2 1268072.PSAB_17450 8.057e-50 198.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,26Q9F@186822|Paenibacillaceae 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC HSJS1_k127_786811_4 1341151.ASZU01000010_gene1884 1.756e-05 47.0 COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,27BS9@186824|Thermoactinomycetaceae 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25 HSJS1_k127_788128_3 1449355.JQNR01000004_gene1614 3.348e-17 81.0 COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria 201174|Actinobacteria Q polyketide synthase - - - ko:K13611,ko:K15314 ko01059,ko01130,map01059,map01130 M00824,M00825 R11435 - ko00000,ko00001,ko00002,ko01004,ko01008 - - - Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HSJS1_k127_788128_1 443255.SCLAV_p1350 5.827e-168 545.0 COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria 201174|Actinobacteria Q polyketide synthase - - - ko:K13611,ko:K15314 ko01059,ko01130,map01059,map01130 M00824,M00825 R11435 - ko00000,ko00001,ko00002,ko01004,ko01008 - - - Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HSJS1_k127_788128_2 449447.MAE_12850 1.356e-108 361.0 COG1805@1|root,COG1805@2|Bacteria 2|Bacteria C FMN binding nqrB GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 ko:K00347,ko:K21163 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002,ko01000 - - - NQR2_RnfD_RnfE HSJS1_k127_788128_0 497965.Cyan7822_0306 1.638e-207 658.0 COG4658@1|root,COG4658@2|Bacteria,1GBPJ@1117|Cyanobacteria 1117|Cyanobacteria C ASPIC and UnbV - - - ko:K21162 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002 - - - UnbV_ASPIC,VCBS HSJS1_k127_79069_1 379066.GAU_2186 2.832e-30 123.0 COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Cold shock protein domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD HSJS1_k127_79069_4 215803.DB30_2528 0.0002332 50.0 2BFCF@1|root,3295Q@2|Bacteria,1QNB9@1224|Proteobacteria,433TW@68525|delta/epsilon subdivisions,2X9YD@28221|Deltaproteobacteria,2YVW3@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_79069_2 502025.Hoch_5195 4.244e-16 90.0 2AGR1@1|root,316YS@2|Bacteria,1PY6N@1224|Proteobacteria,4354R@68525|delta/epsilon subdivisions,2WZFS@28221|Deltaproteobacteria,2Z21K@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_79069_3 688245.CtCNB1_0905 2.829e-05 53.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,4AEJH@80864|Comamonadaceae 28216|Betaproteobacteria H PFAM Transcriptional coactivator pterin dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a HSJS1_k127_79069_0 1267535.KB906767_gene1738 7.328e-90 317.0 COG3829@1|root,COG3829@2|Bacteria,3Y6K2@57723|Acidobacteria 57723|Acidobacteria KT Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - Sigma54_activat,Yop-YscD_cpl HSJS1_k127_801095_1 269084.syc2102_c 2.535e-66 233.0 COG4229@1|root,COG4229@2|Bacteria,1G59P@1117|Cyanobacteria,1H3Y4@1129|Synechococcus 1117|Cyanobacteria F Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) mtnC - 3.1.3.77 ko:K09880 ko00270,ko01100,map00270,map01100 M00034 R07395 RC02779 ko00000,ko00001,ko00002,ko01000 - - - HAD_2,Hydrolase HSJS1_k127_801095_0 530564.Psta_3140 4.988e-68 242.0 COG1791@1|root,COG1791@2|Bacteria,2J2NB@203682|Planctomycetes 203682|Planctomycetes H Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD - 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD HSJS1_k127_801095_2 1173264.KI913949_gene709 2.297e-55 203.0 COG0235@1|root,COG0235@2|Bacteria,1G2EA@1117|Cyanobacteria,1H8JN@1150|Oscillatoriales 1117|Cyanobacteria E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.2.1.109 ko:K08964 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II HSJS1_k127_808092_3 1894.JOER01000021_gene3977 1.16e-06 59.0 COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria 201174|Actinobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding HSJS1_k127_808092_0 237368.SCABRO_02229 5.394e-128 422.0 COG0304@1|root,COG0304@2|Bacteria,2J1Z9@203682|Planctomycetes 203682|Planctomycetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt HSJS1_k127_808092_2 562970.Btus_1445 1.632e-41 169.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF_1 - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt HSJS1_k127_808092_1 1500890.JQNL01000001_gene1692 6.755e-58 220.0 COG0644@1|root,COG0644@2|Bacteria,1MZ3Z@1224|Proteobacteria,1S47W@1236|Gammaproteobacteria,1X4IT@135614|Xanthomonadales 135614|Xanthomonadales C Halogenase - - - - - - - - - - - - Trp_halogenase HSJS1_k127_815523_3 1234364.AMSF01000068_gene2136 1.11e-43 172.0 COG2866@1|root,COG2866@2|Bacteria,1QHMD@1224|Proteobacteria,1RYUG@1236|Gammaproteobacteria,1X3DF@135614|Xanthomonadales 135614|Xanthomonadales E Carboxypeptidase - - - - - - - - - - - - Peptidase_M14 HSJS1_k127_815523_2 349521.HCH_00727 2.819e-45 175.0 292MS@1|root,2ZQ5N@2|Bacteria,1N3H9@1224|Proteobacteria,1SGA5@1236|Gammaproteobacteria,1XQTS@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - HSJS1_k127_815523_0 330214.NIDE1306 1.847e-61 213.0 COG0048@1|root,COG0048@2|Bacteria,3J0IU@40117|Nitrospirae 40117|Nitrospirae J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 HSJS1_k127_815523_1 644282.Deba_2942 4.754e-61 213.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 HSJS1_k127_817521_0 1283300.ATXB01000001_gene1189 6.454e-136 452.0 COG3211@1|root,COG3211@2|Bacteria,1R7E2@1224|Proteobacteria,1SCSQ@1236|Gammaproteobacteria,1XGF9@135618|Methylococcales 135618|Methylococcales S Bacterial protein of unknown function (DUF839) - - - - - - - - - - - - DUF839 HSJS1_k127_818638_1 1048339.KB913029_gene1452 2.438e-93 310.0 COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4ERY0@85013|Frankiales 201174|Actinobacteria J SpoU rRNA Methylase family trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase HSJS1_k127_818638_2 211114.JOEF01000008_gene1251 1.055e-41 168.0 COG2207@1|root,COG2207@2|Bacteria,2IBP1@201174|Actinobacteria,4E2SX@85010|Pseudonocardiales 201174|Actinobacteria K AraC-binding-like domain - - - - - - - - - - - - AraC_binding_2,HTH_18 HSJS1_k127_818638_0 32042.PstZobell_09567 9.831e-122 399.0 COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria,1Z2DE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Belongs to the carbamate kinase family arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - iE2348C_1286.E2348C_0454,iECED1_1282.ECED1_0540,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641 AA_kinase HSJS1_k127_818638_4 980584.AFPB01000085_gene2512 4.384e-22 107.0 28K2C@1|root,2ZC8E@2|Bacteria,4NN01@976|Bacteroidetes,1I411@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - Phenol_MetA_deg HSJS1_k127_818638_3 404589.Anae109_4457 1.561e-33 149.0 COG4191@1|root,COG4191@2|Bacteria,1R9SH@1224|Proteobacteria,42QAE@68525|delta/epsilon subdivisions,2WM61@28221|Deltaproteobacteria,2Z2WP@29|Myxococcales 28221|Deltaproteobacteria T PFAM ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,dCache_1 HSJS1_k127_818638_5 1125863.JAFN01000001_gene1446 3.966e-12 71.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_822284_2 861299.J421_6231 2.077e-36 151.0 COG0491@1|root,COG0491@2|Bacteria,1ZU73@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B HSJS1_k127_822284_0 335543.Sfum_0899 2.996e-214 682.0 COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2MRD0@213462|Syntrophobacterales 28221|Deltaproteobacteria P Ion channel - - - - - - - - - - - - Ion_trans_2,TrkA_C,TrkA_N HSJS1_k127_822284_3 1192034.CAP_6903 2.119e-24 117.0 COG0484@1|root,COG0484@2|Bacteria,1QXUZ@1224|Proteobacteria,43C7N@68525|delta/epsilon subdivisions,2X7HY@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388 HSJS1_k127_822284_1 378806.STAUR_3484 1.353e-61 216.0 COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales 28221|Deltaproteobacteria Q PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT HSJS1_k127_822284_4 765912.Thimo_2792 4.976e-18 89.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1NAY1@1224|Proteobacteria,1RP74@1236|Gammaproteobacteria,1WWDY@135613|Chromatiales 135613|Chromatiales J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N HSJS1_k127_823422_0 1232410.KI421415_gene2964 3.741e-54 199.0 COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,43T4G@69541|Desulfuromonadales 28221|Deltaproteobacteria L THUMP rlmL - 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 HSJS1_k127_823422_1 1384054.N790_09165 6.773e-30 135.0 COG1075@1|root,COG1075@2|Bacteria,1PHER@1224|Proteobacteria,1T7T0@1236|Gammaproteobacteria,1X9P7@135614|Xanthomonadales 135614|Xanthomonadales S Lecithin:cholesterol acyltransferase - - - - - - - - - - - - LCAT HSJS1_k127_823422_2 1379270.AUXF01000001_gene2602 2.442e-26 113.0 COG1278@1|root,COG1278@2|Bacteria,1ZV0Z@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Ribonuclease B OB domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD HSJS1_k127_845472_0 378806.STAUR_7745 2.202e-69 259.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria 1224|Proteobacteria U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - CHAT,PD40,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8 HSJS1_k127_848073_1 638303.Thal_1281 9.582e-16 79.0 COG1232@1|root,COG1232@2|Bacteria,2G3UP@200783|Aquificae 200783|Aquificae H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemG - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase HSJS1_k127_848073_0 344747.PM8797T_03935 3.738e-214 677.0 COG0457@1|root,COG0457@2|Bacteria,2IXP3@203682|Planctomycetes 203682|Planctomycetes C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,TPR_16 HSJS1_k127_85261_1 1395571.TMS3_0100225 1.663e-278 860.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 HSJS1_k127_85261_0 743720.Psefu_3960 1.303e-316 977.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1YXU8@136845|Pseudomonas putida group 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 HSJS1_k127_85261_2 187272.Mlg_2775 2.159e-102 344.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales 135613|Chromatiales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH HSJS1_k127_85261_3 340.xcc-b100_1373 1.873e-53 203.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1X45E@135614|Xanthomonadales 135614|Xanthomonadales S permease perM - - - - - - - - - - - AI-2E_transport HSJS1_k127_854947_1 1125863.JAFN01000001_gene3410 7.382e-84 294.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD HSJS1_k127_854947_0 338963.Pcar_3001 7.641e-308 967.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,43SE5@69541|Desulfuromonadales 28221|Deltaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran HSJS1_k127_869455_2 1148.1652047 1.954e-34 139.0 COG3296@1|root,COG3296@2|Bacteria,1G8MY@1117|Cyanobacteria,1H6JN@1142|Synechocystis 1117|Cyanobacteria S Domain of unknown function (DUF4870) - - - ko:K09940 - - - - ko00000 - - - DUF4870 HSJS1_k127_869455_1 644966.Tmar_1631 1.81e-81 283.0 COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,24B4B@186801|Clostridia 186801|Clostridia C Reduction of activated sulfate into sulfite - - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct HSJS1_k127_869455_0 1382306.JNIM01000001_gene2460 2.898e-82 284.0 COG0007@1|root,COG0007@2|Bacteria,2G6EG@200795|Chloroflexi 200795|Chloroflexi H Tetrapyrrole (Corrin/Porphyrin) Methylases - - 2.1.1.107,4.2.1.75 ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - - TP_methylase HSJS1_k127_869455_4 1156935.QWE_04198 8.568e-14 79.0 COG2227@1|root,COG2227@2|Bacteria,1N2VZ@1224|Proteobacteria,2TU4Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Magnesium-protoporphyrin IX methyltransferase domain protein bchM GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.11 ko:K03428 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R04237 RC00003,RC00460 ko00000,ko00001,ko01000 - - - MTS,Mg-por_mtran_C,PrmA HSJS1_k127_869455_3 1121923.GPUN_2299 9.124e-17 82.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,464NI@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124 Transketolase_N HSJS1_k127_890516_2 1121920.AUAU01000002_gene2039 4.803e-75 259.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,3Y6VT@57723|Acidobacteria 57723|Acidobacteria C Malic enzyme, NAD binding domain - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic HSJS1_k127_890516_3 926550.CLDAP_01340 9.444e-12 76.0 arCOG12117@1|root,2Z9N1@2|Bacteria,2G9RJ@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF3891) - - - - - - - - - - - - DUF3891 HSJS1_k127_890516_0 869210.Marky_1642 8.381e-177 567.0 COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E PFAM aromatic amino acid beta-eliminating lyase threonine aldolase tnaA - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase HSJS1_k127_890516_1 502025.Hoch_0089 1.875e-102 342.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42T5F@68525|delta/epsilon subdivisions,2WQVP@28221|Deltaproteobacteria,2YU42@29|Myxococcales 28221|Deltaproteobacteria C FMN-dependent dehydrogenase - - 1.1.3.46 ko:K16422 ko00261,ko01055,ko01130,map00261,map01055,map01130 - R06633 RC00240 ko00000,ko00001,ko01000 - - - FMN_dh HSJS1_k127_892747_1 525897.Dbac_2639 2.683e-72 250.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2M8X8@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 51 pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase HSJS1_k127_892747_0 621372.ACIH01000203_gene2390 2.56e-87 308.0 COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae 91061|Bacilli H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase HSJS1_k127_892747_3 1007103.AFHW01000151_gene957 2.185e-22 111.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae 91061|Bacilli K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 HSJS1_k127_892747_2 1293054.HSACCH_00630 2.008e-23 107.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WA6Y@53433|Halanaerobiales 186801|Clostridia J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 HSJS1_k127_898063_2 1121861.KB899923_gene3464 9.649e-20 95.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,2JSSI@204441|Rhodospirillales 204441|Rhodospirillales S Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C HSJS1_k127_898063_0 204669.Acid345_4218 1.126e-111 389.0 COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria,2JIAX@204432|Acidobacteriia 204432|Acidobacteriia K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 HSJS1_k127_898063_1 1340493.JNIF01000003_gene2109 2.614e-41 169.0 COG0532@1|root,COG0532@2|Bacteria,3Y3UG@57723|Acidobacteria 57723|Acidobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N HSJS1_k127_899313_1 1216976.AX27061_2220 0.0001011 44.0 COG0457@1|root,COG0457@2|Bacteria,1R8D4@1224|Proteobacteria,2W2VK@28216|Betaproteobacteria,3T834@506|Alcaligenaceae 28216|Betaproteobacteria S Protein of unknown function (DUF560) - - - - - - - - - - - - DUF560 HSJS1_k127_899313_0 1144275.COCOR_05366 3.772e-15 90.0 2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_899313_2 1201293.AKXQ01000006_gene265 0.0004039 54.0 COG3391@1|root,COG3391@2|Bacteria,1MX9P@1224|Proteobacteria,1RQU8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Domain of unknown function (DUF4842) VPA1172 - - - - - - - - - - - DUF4842 HSJS1_k127_913052_0 1122137.AQXF01000003_gene1948 1.127e-123 423.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2TRI9@28211|Alphaproteobacteria 28211|Alphaproteobacteria K exporters of the RND superfamily MA20_16090 - - ko:K07003 - - - - ko00000 - - - MMPL HSJS1_k127_913052_4 1122222.AXWR01000038_gene479 2.734e-59 214.0 COG0652@1|root,COG0652@2|Bacteria 2|Bacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase HSJS1_k127_913052_6 1380394.JADL01000011_gene4032 2.479e-51 187.0 COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,2U848@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phosphoesterase - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 HSJS1_k127_913052_1 1384056.N787_02590 4.931e-108 360.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XAD0@135614|Xanthomonadales 135614|Xanthomonadales S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B HSJS1_k127_913052_3 1134912.AJTV01000030_gene2088 1.382e-66 251.0 COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,1MYCW@1224|Proteobacteria 1224|Proteobacteria Q Belongs to the peptidase S8 family - - - - - - - - - - - - PA HSJS1_k127_913052_2 1166948.JPZL01000001_gene3158 4.662e-81 282.0 COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,1RSAG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 HSJS1_k127_913052_7 1203606.HMPREF1526_00052 2.153e-44 180.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,36DDB@31979|Clostridiaceae 186801|Clostridia F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin HSJS1_k127_913052_5 1140.Synpcc7942_1010 4.535e-56 208.0 COG1187@1|root,COG1187@2|Bacteria,1G1P4@1117|Cyanobacteria,1GYDB@1129|Synechococcus 1117|Cyanobacteria J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 HSJS1_k127_913052_9 330214.NIDE1418 3.982e-41 161.0 COG1386@1|root,COG1386@2|Bacteria,3J15Z@40117|Nitrospirae 40117|Nitrospirae D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB HSJS1_k127_913052_8 518766.Rmar_1317 1.103e-42 168.0 COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,1FJFB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA HSJS1_k127_915123_6 1047013.AQSP01000109_gene2438 2.912e-52 189.0 COG1327@1|root,COG1327@2|Bacteria,2NPEU@2323|unclassified Bacteria 2|Bacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone HSJS1_k127_915123_10 1121439.dsat_0652 9.225e-14 79.0 COG0071@1|root,COG0071@2|Bacteria,1PV70@1224|Proteobacteria,42WBT@68525|delta/epsilon subdivisions,2WRS1@28221|Deltaproteobacteria,2MC2E@213115|Desulfovibrionales 28221|Deltaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 HSJS1_k127_915123_0 1123376.AUIU01000002_gene1663 2.914e-288 910.0 COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae 40117|Nitrospirae O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C HSJS1_k127_915123_9 269799.Gmet_3213 1.387e-41 173.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43UHS@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C HSJS1_k127_915123_7 644966.Tmar_0094 4.535e-51 200.0 COG1225@1|root,COG1225@2|Bacteria,1UV64@1239|Firmicutes,24HTS@186801|Clostridia 186801|Clostridia O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA HSJS1_k127_915123_4 406552.NJ7G_1883 1.936e-79 284.0 COG1173@1|root,arCOG00748@2157|Archaea,2XUIX@28890|Euryarchaeota,23T5H@183963|Halobacteria 183963|Halobacteria P COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N HSJS1_k127_915123_8 861299.J421_1287 6.078e-45 169.0 COG1956@1|root,COG1956@2|Bacteria,1ZTQQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 HSJS1_k127_915123_1 1499967.BAYZ01000076_gene838 6.403e-114 374.0 COG0601@1|root,COG0601@2|Bacteria 2|Bacteria P nitrogen compound transport - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 HSJS1_k127_915123_5 1265502.KB905951_gene862 2.278e-77 293.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9V8@80864|Comamonadaceae 28216|Betaproteobacteria T response regulator - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_915123_3 1123242.JH636434_gene5049 1.002e-81 290.0 COG0128@1|root,COG0128@2|Bacteria,2IXRF@203682|Planctomycetes 203682|Planctomycetes E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase HSJS1_k127_915123_2 1232410.KI421412_gene446 6.136e-86 292.0 COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,42Q0E@68525|delta/epsilon subdivisions,2WITX@28221|Deltaproteobacteria,43SDK@69541|Desulfuromonadales 28221|Deltaproteobacteria S Metallo-beta-lactamase superfamily - - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 HSJS1_k127_917473_1 883126.HMPREF9710_03795 3.631e-120 400.0 COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,2WCZI@28216|Betaproteobacteria,476J7@75682|Oxalobacteraceae 28216|Betaproteobacteria S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 HSJS1_k127_917473_0 448385.sce3415 5.67e-205 662.0 COG0514@1|root,COG0550@1|root,COG0514@2|Bacteria,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42NQG@68525|delta/epsilon subdivisions,2WJXC@28221|Deltaproteobacteria,2YU8A@29|Myxococcales 28221|Deltaproteobacteria L ATP-dependent DNA helicase RecQ topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - DEAD,HRDC,Helicase_C,RecQ_Zn_bind,Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom HSJS1_k127_919445_1 391625.PPSIR1_25771 2.118e-36 139.0 COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,42VTI@68525|delta/epsilon subdivisions,2WW2V@28221|Deltaproteobacteria,2YYXY@29|Myxococcales 28221|Deltaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - GSH-S_ATP HSJS1_k127_919445_2 266117.Rxyl_1803 3.668e-36 147.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CPNY@84995|Rubrobacteria 84995|Rubrobacteria K helix_turn_helix, cAMP Regulatory protein - - - ko:K21564 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding HSJS1_k127_919445_0 1232410.KI421415_gene2947 0.0 1594.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,42P6X@68525|delta/epsilon subdivisions,2WK8U@28221|Deltaproteobacteria,43U3A@69541|Desulfuromonadales 28221|Deltaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain - - 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Molybdopterin,Molydop_binding HSJS1_k127_924094_0 1047013.AQSP01000121_gene2702 2.932e-122 410.0 COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria 2|Bacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 HSJS1_k127_924094_4 1122137.AQXF01000001_gene2693 2.415e-24 118.0 2EGX5@1|root,33APA@2|Bacteria,1NHMF@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - GGACT HSJS1_k127_924094_3 1349767.GJA_5209 3.612e-32 131.0 2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_924094_5 861299.J421_1409 9.243e-19 95.0 2EV6U@1|root,33NMK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_924094_2 861299.J421_1407 8.701e-33 144.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 HSJS1_k127_924094_1 391625.PPSIR1_37124 8.311e-44 171.0 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family - - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HSJS1_k127_928562_3 794903.OPIT5_07760 1.093e-05 57.0 COG3210@1|root,COG3210@2|Bacteria,46SVB@74201|Verrucomicrobia,3K920@414999|Opitutae 414999|Opitutae U Passenger-associated-transport-repeat - - - - - - - - - - - - PATR HSJS1_k127_928562_0 767817.Desgi_2766 5.357e-169 548.0 COG0671@1|root,COG0671@2|Bacteria,1USD9@1239|Firmicutes 1239|Firmicutes I PAP2 superfamily - - - - - - - - - - - - PAP2 HSJS1_k127_928562_1 768671.ThimaDRAFT_1379 4.947e-57 205.0 COG4636@1|root,COG4636@2|Bacteria,1RH5Y@1224|Proteobacteria,1S50V@1236|Gammaproteobacteria,1WY8M@135613|Chromatiales 135613|Chromatiales S Putative restriction endonuclease - - - - - - - - - - - - Uma2 HSJS1_k127_928562_2 1380358.JADJ01000001_gene1121 1.051e-39 150.0 COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,1S9PQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MarR family transcriptional regulator - - - - - - - - - - - - DUF488 HSJS1_k127_934254_2 1192034.CAP_6447 0.0003157 46.0 COG3518@1|root,COG3518@2|Bacteria,1Q2KF@1224|Proteobacteria,433UA@68525|delta/epsilon subdivisions,2X3H1@28221|Deltaproteobacteria,2YW24@29|Myxococcales 28221|Deltaproteobacteria S Gene 25-like lysozyme - - - ko:K11897 - M00334 - - ko00000,ko00002,ko02044 - - - GPW_gp25 HSJS1_k127_934254_0 448385.sce9338 9.388e-165 539.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,42PR4@68525|delta/epsilon subdivisions,2WJCN@28221|Deltaproteobacteria,2YU04@29|Myxococcales 28221|Deltaproteobacteria S Type VI secretion system, TssF - - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF HSJS1_k127_934254_1 448385.sce9337 5.628e-56 223.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,42VCI@68525|delta/epsilon subdivisions,2XA11@28221|Deltaproteobacteria,2YUXN@29|Myxococcales 28221|Deltaproteobacteria S Type VI secretion, TssG - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG HSJS1_k127_93470_4 215803.DB30_2933 1.719e-09 63.0 COG1470@1|root,COG1629@1|root,COG1470@2|Bacteria,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,439J0@68525|delta/epsilon subdivisions,2X4VG@28221|Deltaproteobacteria,2YZPG@29|Myxococcales 28221|Deltaproteobacteria P CarboxypepD_reg-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_93470_3 1122613.ATUP01000002_gene2540 1.343e-19 105.0 COG0457@1|root,COG3710@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,1PF3H@1224|Proteobacteria,2V7F9@28211|Alphaproteobacteria,43YSF@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - TPR_16,Trans_reg_C HSJS1_k127_93470_0 234267.Acid_0024 6.276e-161 545.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria 2|Bacteria KU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 HSJS1_k127_93470_2 1379698.RBG1_1C00001G1218 1.348e-93 342.0 COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria 2|Bacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase,TPR_8 HSJS1_k127_93470_5 760117.JN27_07500 8.635e-08 58.0 COG3507@1|root,COG3507@2|Bacteria,1R3V6@1224|Proteobacteria,2WBNZ@28216|Betaproteobacteria,4766P@75682|Oxalobacteraceae 28216|Betaproteobacteria G Glycosyl hydrolases family 43 - - - - - - - - - - - - Glyco_hydro_43 HSJS1_k127_93470_1 883126.HMPREF9710_03636 4.537e-159 511.0 COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,2VIS5@28216|Betaproteobacteria,476UZ@75682|Oxalobacteraceae 28216|Betaproteobacteria G Alpha-L-arabinofuranosidase C-terminus asdII - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C HSJS1_k127_944131_1 1185876.BN8_00646 6.569e-68 248.0 COG0739@1|root,COG0739@2|Bacteria,4NEBZ@976|Bacteroidetes,47JJ1@768503|Cytophagia 976|Bacteroidetes M Peptidase family M23 - - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23,SH3_3,SH3_4 HSJS1_k127_944131_3 1206720.BAFQ01000267_gene5633 1.145e-11 68.0 COG3462@1|root,COG3462@2|Bacteria,2GRGM@201174|Actinobacteria,4G49V@85025|Nocardiaceae 201174|Actinobacteria S membrane protein (DUF2078) - - - ko:K08982 - - - - ko00000 - - - SHOCT HSJS1_k127_944131_0 1089550.ATTH01000001_gene1182 5.326e-161 516.0 COG0701@1|root,COG0701@2|Bacteria,4NI2E@976|Bacteroidetes 976|Bacteroidetes S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 HSJS1_k127_944131_2 171693.BN988_02877 5.791e-23 99.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,23IKU@182709|Oceanobacillus 91061|Bacilli P E1-E2 ATPase copB - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase HSJS1_k127_95166_3 861299.J421_5896 6.723e-166 559.0 COG0577@1|root,COG0577@2|Bacteria 861299.J421_5896|- V efflux transmembrane transporter activity - - - - - - - - - - - - - HSJS1_k127_95166_9 861299.J421_0331 3.442e-38 151.0 COG1695@1|root,COG1695@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - PadR HSJS1_k127_95166_2 1123518.ARWI01000001_gene1948 2.543e-219 692.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales 72273|Thiotrichales EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HSJS1_k127_95166_10 452637.Oter_3730 3.435e-34 148.0 COG3509@1|root,COG3509@2|Bacteria 2|Bacteria Q xylan catabolic process - - - - - - - - - - - - CBM9_1,Esterase_phd HSJS1_k127_95166_0 518766.Rmar_0330 2.369e-231 756.0 COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1FIX1@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P CarboxypepD_reg-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_95166_13 566466.NOR53_259 6.271e-10 65.0 29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,1SB4D@1236|Gammaproteobacteria,1JC42@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 HSJS1_k127_95166_11 1121459.AQXE01000005_gene1545 8.814e-27 116.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2MBZF@213115|Desulfovibrionales 28221|Deltaproteobacteria J PFAM Class I peptide chain release factor - - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 HSJS1_k127_95166_5 1089552.KI911559_gene1597 1.075e-84 291.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2TV8D@28211|Alphaproteobacteria,2JRZ3@204441|Rhodospirillales 204441|Rhodospirillales S EamA-like transporter family - - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA HSJS1_k127_95166_8 1217718.ALOU01000046_gene4057 6.035e-51 192.0 COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2VI5K@28216|Betaproteobacteria,1K8C3@119060|Burkholderiaceae 28216|Betaproteobacteria P Eukaryotic-type carbonic anhydrase - - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase,VPEP HSJS1_k127_95166_1 861299.J421_1457 1.439e-225 722.0 COG2274@1|root,COG2274@2|Bacteria,1ZSX6@142182|Gemmatimonadetes 142182|Gemmatimonadetes V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran HSJS1_k127_95166_14 192952.MM_2233 7.222e-07 60.0 arCOG02538@1|root,arCOG02538@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - Big_2,He_PIG,PKD,Peptidase_S8,S-layer HSJS1_k127_95166_15 999141.GME_03617 2.53e-06 56.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 HSJS1_k127_95166_6 1267534.KB906755_gene4692 4.115e-69 256.0 COG0642@1|root,COG2205@2|Bacteria 1267534.KB906755_gene4692|- T PhoQ Sensor - - - - - - - - - - - - - HSJS1_k127_95166_7 1121904.ARBP01000002_gene6976 3.882e-60 231.0 COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes 976|Bacteroidetes T Two component transcriptional regulator, winged helix family - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HSJS1_k127_95166_4 251229.Chro_1886 2.127e-162 539.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3VIJ3@52604|Pleurocapsales 1117|Cyanobacteria T COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,FHA,GGDEF,PAS_3,Response_reg HSJS1_k127_95166_16 1192034.CAP_8621 1.68e-05 51.0 COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales 28221|Deltaproteobacteria P Sulfatase - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - Cu-binding_MopE,Sulfatase HSJS1_k127_95898_3 1122925.KB895382_gene3711 2.503e-19 98.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,26RNE@186822|Paenibacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N HSJS1_k127_95898_2 926566.Terro_1346 3.96e-77 262.0 COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria,2JHPB@204432|Acidobacteriia 204432|Acidobacteriia OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease HSJS1_k127_95898_1 671143.DAMO_2181 1.774e-177 565.0 COG1219@1|root,COG1219@2|Bacteria,2NNN2@2323|unclassified Bacteria 2|Bacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX HSJS1_k127_95898_0 1089553.Tph_c04670 7.627e-279 877.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales 186801|Clostridia O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C HSJS1_k127_963218_3 880073.Calab_3750 2.486e-08 56.0 COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria 2|Bacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972,ko:K10754 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 M00289,M00295 R00382 RC00005 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 HSJS1_k127_963218_5 383372.Rcas_1314 9.161e-06 49.0 2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - HSJS1_k127_963218_4 1499967.BAYZ01000119_gene3173 1.354e-07 54.0 28JE3@1|root,2Z98B@2|Bacteria,2NQ8M@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - AbiEii HSJS1_k127_963218_1 463191.SSEG_04592 2.123e-90 306.0 COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria 201174|Actinobacteria S Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - - - - - - - - - - GATase_4,GATase_6 HSJS1_k127_963218_0 1121930.AQXG01000009_gene258 1.168e-175 577.0 COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,1IVJC@117747|Sphingobacteriia 976|Bacteroidetes T PIN domain ybeZ_1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH HSJS1_k127_963218_2 391625.PPSIR1_11110 2.562e-63 229.0 COG2988@1|root,COG2988@2|Bacteria 2|Bacteria E succinylglutamate desuccinylase activity astE - 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - - AstE_AspA HSJS1_k127_96597_0 997346.HMPREF9374_2906 2.948e-35 154.0 COG0500@1|root,COG0500@2|Bacteria,1V1KE@1239|Firmicutes 1239|Firmicutes Q Methyltransferase tehB - 2.1.1.265 ko:K16868 - - - - ko00000,ko01000 - - - DUF1971,Methyltransf_25,TehB HSJS1_k127_96597_1 1282876.BAOK01000001_gene2353 3.443e-34 136.0 2DBIF@1|root,2Z9FG@2|Bacteria,1QYR5@1224|Proteobacteria,2TTVX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - HSJS1_k127_971712_0 335543.Sfum_1617 1.027e-156 518.0 COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS HSJS1_k127_971712_1 1047013.AQSP01000131_gene1841 7.017e-47 194.0 COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria 2|Bacteria P COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec HSJS1_k127_974036_0 765912.Thimo_2580 1.706e-152 498.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept HSJS1_k127_974036_1 502025.Hoch_2921 7.997e-29 125.0 COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X39N@28221|Deltaproteobacteria,2Z0CB@29|Myxococcales 28221|Deltaproteobacteria L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp HSJS1_k127_97551_2 1242864.D187_006518 5.591e-08 64.0 COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria 68525|delta/epsilon subdivisions S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO HSJS1_k127_97551_1 1499967.BAYZ01000193_gene3921 3.035e-76 267.0 COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria 2|Bacteria H UbiA prenyltransferase family ubiA - - - - - - - - - - - UbiA HSJS1_k127_97551_0 1278073.MYSTI_07079 5.084e-106 366.0 2AQ29@1|root,31F7C@2|Bacteria,1NHC1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - HSJS1_k127_977874_2 485918.Cpin_5924 6.982e-88 303.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IQWN@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Zinc carboxypeptidase - - - - - - - - - - - - ABC_transp_aux,Peptidase_M14 HSJS1_k127_977874_0 1047013.AQSP01000083_gene1192 1.454e-150 490.0 COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria 2|Bacteria T COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains nla19 - - ko:K07713,ko:K07714,ko:K19641 ko02020,map02020 M00499,M00500,M00772 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_977874_1 234267.Acid_1646 1.64e-94 346.0 COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria 57723|Acidobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4 HSJS1_k127_977874_3 1122239.AULS01000011_gene63 5.461e-07 53.0 COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,4FPDE@85023|Microbacteriaceae 201174|Actinobacteria S Phosphoribosyl transferase domain pyrE_1 - - - - - - - - - - - Pribosyltran HSJS1_k127_979412_11 1254432.SCE1572_33175 4.745e-57 205.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales 28221|Deltaproteobacteria S ABC transporter, ATP-binding protein ybiT - - - - - - - - - - - ABC_tran,ABC_tran_Xtn HSJS1_k127_979412_0 1242864.D187_001443 3.077e-280 899.0 COG0421@1|root,COG0457@1|root,COG0421@2|Bacteria,COG0457@2|Bacteria,1QXA2@1224|Proteobacteria,43C3D@68525|delta/epsilon subdivisions,2WUH2@28221|Deltaproteobacteria,2YYH4@29|Myxococcales 28221|Deltaproteobacteria E Spermine/spermidine synthase domain - - - - - - - - - - - - Spermine_synth HSJS1_k127_979412_12 861299.J421_0886 2.035e-54 197.0 COG1595@1|root,COG1595@2|Bacteria,1ZUWT@142182|Gemmatimonadetes 142182|Gemmatimonadetes K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF HSJS1_k127_979412_13 391615.ABSJ01000039_gene1814 8.851e-46 175.0 COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,1S9RI@1236|Gammaproteobacteria,1J728@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase HSJS1_k127_979412_3 1333998.M2A_2366 2.989e-162 541.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,2TV9Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 HSJS1_k127_979412_8 1122137.AQXF01000001_gene2972 7.248e-73 263.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K14981 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HSJS1_k127_979412_7 1150626.PHAMO_40112 6.631e-79 288.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria,2JYVY@204441|Rhodospirillales 204441|Rhodospirillales T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K14980 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1 HSJS1_k127_979412_17 521460.Athe_1856 1.563e-11 74.0 COG2207@1|root,COG2207@2|Bacteria,1UZQJ@1239|Firmicutes,24GN0@186801|Clostridia 186801|Clostridia K PFAM helix-turn-helix- domain containing protein, AraC type - - - - - - - - - - - - HTH_18,dCache_1 HSJS1_k127_979412_5 1235803.C825_05279 1.81e-81 283.0 COG1131@1|root,COG1131@2|Bacteria,4NE3Z@976|Bacteroidetes,2FR55@200643|Bacteroidia,22ZR5@171551|Porphyromonadaceae 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HSJS1_k127_979412_19 1236541.BALL01000002_gene359 0.0001347 54.0 COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria,2QB2S@267890|Shewanellaceae 1236|Gammaproteobacteria S ABC-2 family transporter protein nosY - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2 HSJS1_k127_979412_4 1254432.SCE1572_17585 2.649e-131 437.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales 28221|Deltaproteobacteria T response regulator - - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat HSJS1_k127_979412_9 1235788.C802_00425 9.639e-71 256.0 COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,2FR1C@200643|Bacteroidia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA HSJS1_k127_979412_6 404589.Anae109_3084 2.396e-79 287.0 2C6TZ@1|root,32RHS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_979412_10 861299.J421_4047 1.316e-59 228.0 COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes 2|Bacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,Cu_amine_oxidN1,DUF3471 HSJS1_k127_979412_1 56780.SYN_02261 1.198e-216 703.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MR18@213462|Syntrophobacterales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 HSJS1_k127_979412_16 717606.PaecuDRAFT_3972 4.074e-23 100.0 COG3251@1|root,COG3251@2|Bacteria,1VQAA@1239|Firmicutes,4HRE7@91061|Bacilli,26ZSC@186822|Paenibacillaceae 91061|Bacilli S MbtH-like protein mbtH - - ko:K05375 ko00261,ko01130,map00261,map01130 M00736 R10880 RC00064,RC00141,RC03296,RC03297,RC03298 ko00000,ko00001,ko00002 - - - MbtH HSJS1_k127_979412_2 391587.KAOT1_11447 5.681e-192 616.0 COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,1HZ9A@117743|Flavobacteriia 976|Bacteroidetes O Carbamoyltransferase C-terminus - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N HSJS1_k127_979412_15 291112.PAU_00483 9.149e-30 131.0 2A0ZJ@1|root,30P4V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HSJS1_k127_99964_0 1463854.JOHT01000002_gene2225 1.534e-92 319.0 COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 HSJS1_k127_99964_2 15368.BRADI3G59680.1 4.437e-08 63.0 KOG1565@1|root,KOG1565@2759|Eukaryota,37MGX@33090|Viridiplantae,3GE77@35493|Streptophyta,3KR4Q@4447|Liliopsida,3IBM5@38820|Poales 35493|Streptophyta O Belongs to the peptidase M10A family - GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - ko:K07761,ko:K07999 - - - - ko00000,ko01000,ko01002 - - - PG_binding_1,Peptidase_M10 ## 3651 queries scanned ## Total time (seconds): 267.9051547050476 ## Rate: 13.63 q/s