## Sat Nov 16 04:17:49 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin10/HSJS_2_bin.7.fa -m mmseqs --itype genome -o HSJS_2_bin.7 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HSJS_2_bin.7 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HSJS2_k127_1019649_1	1122947.FR7_4024	2.616e-74	261.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4H32Z@909932|Negativicutes	909932|Negativicutes	P	oligopeptide transport system permease protein OppB	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
HSJS2_k127_1019649_2	255470.cbdbA1037	9.225e-71	252.0	COG1173@1|root,COG1173@2|Bacteria,2G9WH@200795|Chloroflexi,34DKE@301297|Dehalococcoidia	301297|Dehalococcoidia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
HSJS2_k127_1019649_0	314285.KT71_03092	5.742e-94	319.0	COG3246@1|root,COG3246@2|Bacteria,1R4YF@1224|Proteobacteria,1SK8Q@1236|Gammaproteobacteria,1J82J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam:Kce	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
HSJS2_k127_1023391_2	1380390.JIAT01000010_gene3560	5.625e-108	363.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CSIF@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
HSJS2_k127_1023391_0	469383.Cwoe_4214	6.429e-161	517.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	-	-	6.2.1.18	ko:K15232	ko00720,ko01100,ko01120,ko01200,map00720,map01100,map01120,map01200	M00173	R01322	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2
HSJS2_k127_1023391_1	1380390.JIAT01000010_gene3563	3.85e-156	500.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CPSD@84995|Rubrobacteria	84995|Rubrobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
HSJS2_k127_1023391_4	926550.CLDAP_24450	1.36e-48	195.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1023391_5	926550.CLDAP_14690	2.116e-09	66.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
HSJS2_k127_1023391_3	1255043.TVNIR_3070	2.145e-72	248.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1WZYG@135613|Chromatiales	135613|Chromatiales	G	Fructose-bisphosphate aldolase class-I	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
HSJS2_k127_1024586_0	1382306.JNIM01000001_gene1910	4.02e-58	209.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HSJS2_k127_1024586_1	537013.CLOSTMETH_03198	6.588e-52	196.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3WG7D@541000|Ruminococcaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HSJS2_k127_1024586_2	324602.Caur_2015	9.503e-42	169.0	COG0617@1|root,COG0617@2|Bacteria,2G8YQ@200795|Chloroflexi,375MA@32061|Chloroflexia	32061|Chloroflexia	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
HSJS2_k127_1024684_0	479434.Sthe_0907	8.033e-138	447.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HSJS2_k127_1024684_7	937777.Deipe_2486	1.777e-11	76.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	APH,Abhydrolase_6,Hydrolase_4,Peptidase_S9
HSJS2_k127_1024684_2	452637.Oter_3529	7.007e-53	193.0	COG0546@1|root,COG0546@2|Bacteria,46YH3@74201|Verrucomicrobia,3K9K2@414999|Opitutae	414999|Opitutae	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HSJS2_k127_1024684_3	258533.BN977_04337	4.634e-35	141.0	COG3871@1|root,COG3871@2|Bacteria,2IFC3@201174|Actinobacteria,238T2@1762|Mycobacteriaceae	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_1024684_1	1121946.AUAX01000027_gene7984	5.08e-79	283.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DB58@85008|Micromonosporales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS2_k127_1024684_4	1380394.JADL01000005_gene5603	1.136e-30	128.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2U5AR@28211|Alphaproteobacteria,2JTW8@204441|Rhodospirillales	204441|Rhodospirillales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
HSJS2_k127_1024684_5	1173027.Mic7113_1716	4.49e-27	120.0	COG1853@1|root,COG1853@2|Bacteria,1G2RV@1117|Cyanobacteria,1H7U3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HSJS2_k127_1024684_6	1205680.CAKO01000002_gene2376	3.791e-19	90.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2TTR7@28211|Alphaproteobacteria,2JQ54@204441|Rhodospirillales	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_1030424_0	1134413.ANNK01000141_gene2985	5.589e-39	149.0	COG1028@1|root,COG1028@2|Bacteria,1UXZ5@1239|Firmicutes,4HBJV@91061|Bacilli,1ZDW8@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_1043712_0	247490.KSU1_B0257	0.0	1453.0	COG0243@1|root,COG0243@2|Bacteria,2J2QN@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin
HSJS2_k127_1043712_2	595537.Varpa_5318	5.615e-28	126.0	COG1247@1|root,COG1247@2|Bacteria,1R6UW@1224|Proteobacteria,2W2QC@28216|Betaproteobacteria,4AHQC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_1043712_1	448385.sce3269	2.482e-87	300.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2WINT@28221|Deltaproteobacteria,2YUPM@29|Myxococcales	28221|Deltaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
HSJS2_k127_1052024_2	8479.XP_005313973.1	3.547e-22	102.0	COG0237@1|root,COG1019@1|root,KOG3220@2759|Eukaryota,KOG3351@2759|Eukaryota,38H33@33154|Opisthokonta,3BCJW@33208|Metazoa,3CSPG@33213|Bilateria,483JW@7711|Chordata,4918F@7742|Vertebrata,4CG0A@8459|Testudines	33208|Metazoa	H	Dephospho-CoA kinase	COASY	GO:0000003,GO:0001667,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0003006,GO:0003674,GO:0003824,GO:0004140,GO:0004595,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005759,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007300,GO:0007303,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0010631,GO:0015936,GO:0015937,GO:0016020,GO:0016301,GO:0016310,GO:0016477,GO:0016482,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019867,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030707,GO:0030855,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040011,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046390,GO:0046483,GO:0046907,GO:0048468,GO:0048477,GO:0048513,GO:0048563,GO:0048569,GO:0048609,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0055086,GO:0055088,GO:0055090,GO:0060429,GO:0060562,GO:0065007,GO:0065008,GO:0070013,GO:0070328,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090130,GO:0090132,GO:0090407,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,2.7.7.3	ko:K02318	ko00770,ko01100,map00770,map01100	M00120	R00130,R03035	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,CoaE
HSJS2_k127_1052024_0	1121106.JQKB01000054_gene4466	1.94e-146	496.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2JPKU@204441|Rhodospirillales	204441|Rhodospirillales	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HSJS2_k127_1052024_1	479434.Sthe_1797	5.389e-78	272.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
HSJS2_k127_1066030_4	909663.KI867149_gene3397	6.585e-16	82.0	COG4274@1|root,COG4274@2|Bacteria,1PUJQ@1224|Proteobacteria,42XN6@68525|delta/epsilon subdivisions,2WTHH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
HSJS2_k127_1066030_1	1043493.BBLU01000014_gene1312	1.091e-76	269.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HSJS2_k127_1066030_3	1123389.ATXJ01000047_gene435	9.187e-19	96.0	COG1277@1|root,COG1277@2|Bacteria,1WN4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HSJS2_k127_1066030_0	479434.Sthe_2695	4.902e-126	434.0	COG5001@1|root,COG5001@2|Bacteria,2G7UT@200795|Chloroflexi,27Y1B@189775|Thermomicrobia	189775|Thermomicrobia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
HSJS2_k127_1066030_2	585531.HMPREF0063_10436	3.767e-47	173.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4DN46@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_107076_0	1382356.JQMP01000003_gene2108	1.166e-93	330.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
HSJS2_k127_1070940_0	330214.NIDE1937	0.0	1311.0	COG0209@1|root,COG0209@2|Bacteria,3J0MG@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
HSJS2_k127_1070940_1	667014.Thein_1281	1.082e-115	379.0	COG1350@1|root,COG1350@2|Bacteria,2GHCP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS2_k127_107341_0	113395.AXAI01000003_gene5746	1.412e-81	280.0	COG2050@1|root,COG2050@2|Bacteria,1R5RX@1224|Proteobacteria,2U1DZ@28211|Alphaproteobacteria,3JVKP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Thioesterase-like superfamily	MA20_24410	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
HSJS2_k127_107341_1	1121272.KB903249_gene1664	6.549e-62	243.0	COG3292@1|root,COG3292@2|Bacteria,2I71F@201174|Actinobacteria,4DKYH@85008|Micromonosporales	201174|Actinobacteria	T	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_107341_3	1206744.BAGL01000063_gene4727	1.353e-35	142.0	COG0662@1|root,COG0662@2|Bacteria,2IHU8@201174|Actinobacteria,4G2DP@85025|Nocardiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS2_k127_107341_2	1205680.CAKO01000002_gene2220	1.382e-40	153.0	2BRR9@1|root,32KR1@2|Bacteria,1P9A5@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_107341_4	1313172.YM304_12600	2.21e-14	74.0	2DBSD@1|root,2ZARI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1081893_2	1121272.KB903255_gene5840	3.567e-41	155.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4D8JJ@85008|Micromonosporales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HSJS2_k127_1081893_1	383372.Rcas_0200	3.349e-88	307.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi,37543@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS2_k127_1081893_0	479434.Sthe_1676	3.666e-126	428.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi,27XKM@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HSJS2_k127_1091560_1	1380394.JADL01000009_gene3144	1.586e-84	292.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,2JXDQ@204441|Rhodospirillales	204441|Rhodospirillales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
HSJS2_k127_1091560_0	926550.CLDAP_25840	8.038e-152	492.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yteT	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HSJS2_k127_1093246_3	762376.AXYL_04619	5.654e-43	164.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2W0TD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1093246_4	35754.JNYJ01000021_gene600	6.677e-43	169.0	COG0406@1|root,COG0406@2|Bacteria,2IJ7S@201174|Actinobacteria,4DDQU@85008|Micromonosporales	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HSJS2_k127_1093246_6	391625.PPSIR1_07588	6.11e-23	106.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HSJS2_k127_1093246_1	1068980.ARVW01000001_gene5807	7.193e-93	326.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,4E22C@85010|Pseudonocardiales	201174|Actinobacteria	I	lipid-transfer protein	ltp2	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
HSJS2_k127_1093246_5	517722.AEUE01000001_gene2844	2.442e-32	132.0	COG1545@1|root,COG1545@2|Bacteria,1R44D@1224|Proteobacteria,2U9D4@28211|Alphaproteobacteria,2K6V9@204457|Sphingomonadales	204457|Sphingomonadales	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_1093246_0	192875.XP_004342722.1	7.772e-154	503.0	COG0028@1|root,KOG1185@2759|Eukaryota,38EFU@33154|Opisthokonta	33154|Opisthokonta	EH	thiamine pyrophosphate binding	HACL1	GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681	-	ko:K12261	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS2_k127_1093246_2	1206732.BAGD01000054_gene1961	1.633e-76	266.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_1093661_1	765912.Thimo_2694	3.728e-71	254.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria,1WWMI@135613|Chromatiales	135613|Chromatiales	O	ADP-ribosyl-(Dinitrogen reductase) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HSJS2_k127_1093661_0	552811.Dehly_1197	1.284e-92	327.0	COG4826@1|root,COG4826@2|Bacteria,2GBWN@200795|Chloroflexi,34D50@301297|Dehalococcoidia	301297|Dehalococcoidia	M	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
HSJS2_k127_1098224_5	2074.JNYD01000024_gene2844	1.494e-47	190.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1098224_6	521098.Aaci_1851	1.393e-38	160.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_1098224_0	1040989.AWZU01000012_gene1389	3.844e-168	550.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,2U0T4@28211|Alphaproteobacteria,3JRE4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
HSJS2_k127_1098224_2	402881.Plav_2623	1.698e-75	274.0	COG2267@1|root,COG2267@2|Bacteria,1PFMC@1224|Proteobacteria,2UG1M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_1098224_1	1206737.BAGF01000070_gene4446	1.306e-125	420.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4G5VP@85025|Nocardiaceae	201174|Actinobacteria	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HSJS2_k127_1098224_4	1380394.JADL01000001_gene2358	7.342e-62	220.0	COG2128@1|root,COG2128@2|Bacteria,1PNA5@1224|Proteobacteria,2U0KT@28211|Alphaproteobacteria,2JWBA@204441|Rhodospirillales	204441|Rhodospirillales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HSJS2_k127_1098224_10	889378.Spiaf_0299	8.331e-20	95.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K09766,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	DUF2225,cNMP_binding
HSJS2_k127_1098224_8	1144275.COCOR_05742	3.391e-33	137.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria,2Z1HI@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HSJS2_k127_1098224_3	1445613.JALM01000003_gene5062	3.751e-65	237.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4E10C@85010|Pseudonocardiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4,Peptidase_S9
HSJS2_k127_1098224_7	264732.Moth_0909	1.705e-38	153.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,42EM8@68295|Thermoanaerobacterales	186801|Clostridia	T	protein phosphatase 2C domain protein	prpC	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
HSJS2_k127_1098224_9	290397.Adeh_2438	1.881e-20	99.0	COG1032@1|root,COG1032@2|Bacteria,1Q3ZA@1224|Proteobacteria,439T3@68525|delta/epsilon subdivisions,2X567@28221|Deltaproteobacteria,2Z064@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HSJS2_k127_1105381_1	1121926.AXWO01000001_gene3351	1.309e-24	105.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4EZJ4@85014|Glycomycetales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
HSJS2_k127_1105381_2	457429.ABJI02000832_gene2528	5.805e-20	100.0	2ATW3@1|root,31JFB@2|Bacteria,2IJBG@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HSJS2_k127_1105381_0	552811.Dehly_0746	3.2e-208	665.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,34CUX@301297|Dehalococcoidia	301297|Dehalococcoidia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HSJS2_k127_110544_3	1123504.JQKD01000040_gene2800	3.965e-09	63.0	COG0770@1|root,COG2843@1|root,COG4627@1|root,COG0770@2|Bacteria,COG2843@2|Bacteria,COG4627@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,4AEVE@80864|Comamonadaceae	28216|Betaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	Mur_ligase_M,PGA_cap
HSJS2_k127_110544_2	566461.SSFG_00713	1.443e-22	100.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
HSJS2_k127_110544_1	391625.PPSIR1_23474	1.723e-43	163.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HSJS2_k127_110544_0	1205680.CAKO01000037_gene1298	4.568e-290	908.0	COG0439@1|root,COG1038@1|root,COG4799@1|root,COG0439@2|Bacteria,COG1038@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria,2JZ2C@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
HSJS2_k127_1106200_6	867903.ThesuDRAFT_01449	1.32e-09	63.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3WCEI@538999|Clostridiales incertae sedis	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
HSJS2_k127_1106200_1	317619.ANKN01000117_gene1333	2.009e-83	293.0	COG0150@1|root,COG0150@2|Bacteria,1G1WY@1117|Cyanobacteria,1MKTW@1212|Prochloraceae	1117|Cyanobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HSJS2_k127_1106200_0	555088.DealDRAFT_1868	3.151e-147	482.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,42JNM@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HSJS2_k127_1106200_2	497321.C664_16008	1.787e-34	138.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,2KWFV@206389|Rhodocyclales	206389|Rhodocyclales	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
HSJS2_k127_1106200_5	1094980.Mpsy_2603	4.305e-21	94.0	COG2835@1|root,arCOG04124@2157|Archaea,2XZRS@28890|Euryarchaeota,2NA4S@224756|Methanomicrobia	224756|Methanomicrobia	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
HSJS2_k127_1106200_3	2754.EH55_08825	1.529e-32	133.0	COG0801@1|root,COG0801@2|Bacteria,3TB8E@508458|Synergistetes	508458|Synergistetes	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
HSJS2_k127_1106200_4	1382356.JQMP01000003_gene1503	1.323e-24	104.0	COG0294@1|root,COG0294@2|Bacteria,2G6A6@200795|Chloroflexi,27XJT@189775|Thermomicrobia	189775|Thermomicrobia	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HSJS2_k127_1109624_6	1458427.BAWN01000032_gene1770	5.011e-07	59.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,4ADHA@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
HSJS2_k127_1109624_5	661478.OP10G_3097	6.38e-21	101.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
HSJS2_k127_1109624_0	479434.Sthe_0989	1.777e-133	448.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	189775|Thermomicrobia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HSJS2_k127_1109624_4	1288963.ADIS_1091	5.638e-37	159.0	COG3836@1|root,COG3836@2|Bacteria,4NJ5Y@976|Bacteroidetes,47NC8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HSJS2_k127_1109624_1	1207063.P24_08459	2.782e-115	382.0	COG1680@1|root,COG1680@2|Bacteria,1MXHB@1224|Proteobacteria,2U4GK@28211|Alphaproteobacteria,2JRE5@204441|Rhodospirillales	204441|Rhodospirillales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS2_k127_1109624_3	1227488.C477_01530	7.615e-42	167.0	COG0596@1|root,arCOG01648@2157|Archaea,2XW5K@28890|Euryarchaeota,23TTR@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
HSJS2_k127_1109624_2	639283.Snov_2536	3.006e-55	208.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3EYS2@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1110987_2	196162.Noca_0045	4.545e-05	51.0	COG2030@1|root,COG2030@2|Bacteria,2GXE5@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS2_k127_1110987_0	68219.JNXI01000004_gene2564	2.332e-72	259.0	COG1752@1|root,COG1752@2|Bacteria,2I9XW@201174|Actinobacteria	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HSJS2_k127_1110987_1	235909.GK1954	4.988e-61	224.0	COG0111@1|root,COG0111@2|Bacteria,1TQ7W@1239|Firmicutes,4HDEC@91061|Bacilli,1WG92@129337|Geobacillus	91061|Bacilli	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS2_k127_1113155_2	1333998.M2A_1300	1.248e-83	290.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2U36X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
HSJS2_k127_1113155_1	1313172.YM304_24720	4.992e-103	347.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1113155_3	661478.OP10G_1632	1.723e-67	241.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
HSJS2_k127_1113155_0	1123073.KB899242_gene946	2.55e-116	392.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria,1X3QM@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA ligase	lig3	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
HSJS2_k127_112954_2	316274.Haur_4691	1.395e-06	61.0	COG0631@1|root,COG3204@1|root,COG0631@2|Bacteria,COG3204@2|Bacteria,2G72P@200795|Chloroflexi,374Z2@32061|Chloroflexia	32061|Chloroflexia	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_112954_1	357808.RoseRS_0543	1.505e-55	198.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi,375NJ@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
HSJS2_k127_112954_0	1469245.JFBG01000023_gene1282	5.724e-71	243.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
HSJS2_k127_1136927_6	58123.JOFJ01000007_gene627	9.313e-56	208.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4EG2C@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_1136927_4	1128421.JAGA01000003_gene3528	8.857e-90	314.0	COG0771@1|root,COG0771@2|Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
HSJS2_k127_1136927_7	479434.Sthe_0146	9.034e-54	214.0	COG3442@1|root,COG3442@2|Bacteria,2G6KU@200795|Chloroflexi,27XXH@189775|Thermomicrobia	189775|Thermomicrobia	H	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
HSJS2_k127_1136927_8	555088.DealDRAFT_1127	6.646e-37	155.0	COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HSJS2_k127_1136927_9	1382356.JQMP01000001_gene1199	9.122e-36	147.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia	189775|Thermomicrobia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HSJS2_k127_1136927_15	1411685.U062_00031	1.99e-09	63.0	2BQ7M@1|root,32J2C@2|Bacteria,1R32K@1224|Proteobacteria,1T61Z@1236|Gammaproteobacteria,1JBGM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
HSJS2_k127_1136927_0	1162668.LFE_1739	5.301e-160	516.0	COG0498@1|root,COG0498@2|Bacteria,3J0FZ@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	thrC1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS2_k127_1136927_14	330214.NIDE1817	4.762e-14	82.0	COG1135@1|root,COG1135@2|Bacteria,3J0VT@40117|Nitrospirae	40117|Nitrospirae	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
HSJS2_k127_1136927_11	314345.SPV1_14254	1.852e-29	119.0	COG1977@1|root,COG1977@2|Bacteria,1N4Z0@1224|Proteobacteria	1224|Proteobacteria	H	Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HSJS2_k127_1136927_5	1254432.SCE1572_02475	2.308e-73	266.0	COG4552@1|root,COG4552@2|Bacteria,1NBTH@1224|Proteobacteria,42W5G@68525|delta/epsilon subdivisions,2WXK2@28221|Deltaproteobacteria,2YW0Z@29|Myxococcales	28221|Deltaproteobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
HSJS2_k127_1136927_10	1128421.JAGA01000002_gene1873	1.108e-29	123.0	COG1959@1|root,COG1959@2|Bacteria,2NPZX@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HSJS2_k127_1136927_3	269799.Gmet_2988	2.102e-112	370.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,43S9J@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysK-1	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS2_k127_1136927_1	525904.Tter_1313	2.961e-130	428.0	COG0476@1|root,COG1977@1|root,COG0476@2|Bacteria,COG1977@2|Bacteria,2NPX3@2323|unclassified Bacteria	2|Bacteria	H	ThiF family	moeB	-	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
HSJS2_k127_1136927_13	436114.SYO3AOP1_0808	1.2e-23	107.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HSJS2_k127_1136927_2	671143.DAMO_1028	1.583e-118	391.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47,6.1.1.16	ko:K01883,ko:K12339,ko:K21148	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859,R10610	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	PALP,tRNA-synt_1e
HSJS2_k127_1136927_12	1120971.AUCA01000021_gene1048	5.537e-24	103.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,278AM@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HSJS2_k127_1144518_4	1089546.AQUI01000002_gene4369	3.125e-05	52.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4095C@622450|Actinopolysporales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
HSJS2_k127_1144518_3	649638.Trad_1133	2.521e-14	79.0	COG2259@1|root,COG2259@2|Bacteria,1WMY1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HSJS2_k127_1144518_1	483219.LILAB_13530	1.784e-38	151.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
HSJS2_k127_1144518_0	298655.KI912266_gene277	1.909e-76	263.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4EWG8@85013|Frankiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HSJS2_k127_1144518_2	1150864.MILUP08_46685	1.824e-24	116.0	COG1960@1|root,COG1960@2|Bacteria,2H7DI@201174|Actinobacteria,4DC2X@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase type 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_1160197_1	255470.cbdbA1338	9.103e-17	85.0	COG0029@1|root,COG0029@2|Bacteria,2G5JM@200795|Chloroflexi,34D0E@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HSJS2_k127_1160197_0	1382306.JNIM01000001_gene1994	1.279e-153	497.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HSJS2_k127_1161737_5	926550.CLDAP_12770	1.597e-26	113.0	COG0778@1|root,COG0778@2|Bacteria,2G693@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HSJS2_k127_1161737_6	219305.MCAG_02356	2.01e-15	85.0	COG1011@1|root,COG1011@2|Bacteria,2HU2R@201174|Actinobacteria,4DAN7@85008|Micromonosporales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
HSJS2_k127_1161737_4	1120973.AQXL01000123_gene3059	1.346e-30	127.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,278W1@186823|Alicyclobacillaceae	91061|Bacilli	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
HSJS2_k127_1161737_1	1089550.ATTH01000001_gene791	1.331e-101	347.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,1FJ2B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HSJS2_k127_1161737_2	765420.OSCT_2842	1.759e-69	243.0	COG0106@1|root,COG0106@2|Bacteria,2G6EC@200795|Chloroflexi,376JE@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HSJS2_k127_1161737_3	552811.Dehly_0991	8.933e-66	231.0	COG0118@1|root,COG0118@2|Bacteria,2G6FD@200795|Chloroflexi,34D8Q@301297|Dehalococcoidia	301297|Dehalococcoidia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HSJS2_k127_1161737_0	357808.RoseRS_4515	7.377e-183	592.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi,3756T@32061|Chloroflexia	32061|Chloroflexia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HSJS2_k127_1168496_0	266117.Rxyl_1141	7.72e-58	211.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
HSJS2_k127_1168496_1	1382306.JNIM01000001_gene846	5.371e-18	88.0	COG3224@1|root,COG3224@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
HSJS2_k127_1168496_2	406124.ACPC01000010_gene2300	4.32e-12	70.0	COG5460@1|root,COG5460@2|Bacteria,1VNAE@1239|Firmicutes,4HRC9@91061|Bacilli,1ZIV1@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
HSJS2_k127_1169353_0	222534.KB893716_gene1868	9.499e-125	423.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4ESAG@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.6	-	-	MMPL
HSJS2_k127_1169353_1	1104324.P186_2705	1.949e-31	132.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	hadL	-	3.8.1.2,3.8.1.3	ko:K01560,ko:K01561,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
HSJS2_k127_1170512_1	1313172.YM304_17800	8.337e-33	139.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HSJS2_k127_1170512_0	926560.KE387023_gene1698	2.447e-193	621.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1WM1W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KOT	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Response_reg
HSJS2_k127_117117_0	697281.Mahau_0958	3.881e-53	206.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,42F4N@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HSJS2_k127_1177297_3	710685.MycrhN_0100	9.111e-75	269.0	COG1804@1|root,COG1804@2|Bacteria,2IB9E@201174|Actinobacteria,2374W@1762|Mycobacteriaceae	201174|Actinobacteria	C	carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1177297_1	298654.FraEuI1c_6402	5.813e-163	527.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EU7M@85013|Frankiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1177297_2	1121106.JQKB01000027_gene1883	2.914e-134	439.0	COG2141@1|root,COG2141@2|Bacteria,1NKS6@1224|Proteobacteria,2TT87@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_1177297_0	319795.Dgeo_2522	1.389e-188	605.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HSJS2_k127_1177297_4	1382356.JQMP01000003_gene2027	2.397e-62	222.0	COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia	189775|Thermomicrobia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
HSJS2_k127_1178604_2	1238182.C882_3798	2.746e-37	154.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria,2JZ9I@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
HSJS2_k127_1178604_0	1380386.JIAW01000014_gene2793	4.277e-41	168.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,23D0V@1762|Mycobacteriaceae	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
HSJS2_k127_1178604_1	32057.KB217478_gene3605	1.806e-39	160.0	COG0451@1|root,COG0451@2|Bacteria,1G14S@1117|Cyanobacteria,1HIG7@1161|Nostocales	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
HSJS2_k127_1179198_0	765420.OSCT_1624	6.693e-67	237.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,375AQ@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA repair protein RadC	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HSJS2_k127_1179198_1	1121940.AUDZ01000005_gene1675	4.033e-11	72.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XKNI@135619|Oceanospirillales	135619|Oceanospirillales	S	colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
HSJS2_k127_1192287_5	378806.STAUR_6595	4.305e-23	101.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,42S7E@68525|delta/epsilon subdivisions,2X62U@28221|Deltaproteobacteria,2Z38H@29|Myxococcales	28221|Deltaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
HSJS2_k127_1192287_4	1304875.JAFZ01000001_gene1571	2.606e-23	113.0	COG0388@1|root,COG0388@2|Bacteria,3TC5X@508458|Synergistetes	508458|Synergistetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
HSJS2_k127_1192287_2	1379270.AUXF01000001_gene1910	3.103e-62	223.0	COG0179@1|root,COG0179@2|Bacteria,1ZTIG@142182|Gemmatimonadetes	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
HSJS2_k127_1192287_1	525904.Tter_1829	3.439e-97	341.0	COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HSJS2_k127_1192287_0	485913.Krac_11674	1.799e-115	383.0	COG2141@1|root,COG2141@2|Bacteria,2G878@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_1192287_3	309801.trd_A0092	1.657e-31	139.0	COG2807@1|root,COG2807@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_119454_1	1440774.Y900_013065	3.741e-46	171.0	COG3467@1|root,COG3467@2|Bacteria,2H4HR@201174|Actinobacteria,23DFY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_119454_2	926550.CLDAP_21350	1.12e-05	53.0	299CS@1|root,2ZWFP@2|Bacteria,2G9JC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_119454_0	926550.CLDAP_35570	4.965e-65	234.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HSJS2_k127_1210026_3	1304865.JAGF01000001_gene2921	0.0006215	44.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4F0HN@85016|Cellulomonadaceae	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter ATPase subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
HSJS2_k127_1210026_1	1304865.JAGF01000001_gene2920	4.512e-57	210.0	COG0842@1|root,COG0842@2|Bacteria,2IITR@201174|Actinobacteria	201174|Actinobacteria	V	Abc-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
HSJS2_k127_1210026_2	1114959.SZMC14600_06812	7.535e-24	109.0	COG1247@1|root,COG1247@2|Bacteria,2GR9D@201174|Actinobacteria,4EF6Z@85010|Pseudonocardiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_1210026_0	1206741.BAFX01000201_gene25	2.484e-96	331.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FU5C@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HSJS2_k127_1211392_3	196367.JNFG01000015_gene3913	2.833e-29	126.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2WGHU@28216|Betaproteobacteria,1K427@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_1211392_0	1117379.BABA_03844	8.008e-147	483.0	COG4799@1|root,COG4799@2|Bacteria,1VTDE@1239|Firmicutes,4HU50@91061|Bacilli,1ZFG8@1386|Bacillus	91061|Bacilli	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HSJS2_k127_1211392_1	1381123.AYOD01000014_gene2266	1.889e-108	359.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria,43I2S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihA	GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008655,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009164,GO:0009165,GO:0009435,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0034356,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0045437,GO:0046135,GO:0046483,GO:0046496,GO:0046497,GO:0046700,GO:0050263,GO:0051186,GO:0051188,GO:0055086,GO:0070635,GO:0070636,GO:0071704,GO:0072521,GO:0072523,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
HSJS2_k127_1211392_2	485913.Krac_12204	1.933e-29	124.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
HSJS2_k127_1214308_2	309801.trd_0096	2.948e-25	110.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi,27Y9Y@189775|Thermomicrobia	189775|Thermomicrobia	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HSJS2_k127_1214308_1	633697.EubceDRAFT1_0224	6.872e-43	164.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,25WCF@186806|Eubacteriaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HSJS2_k127_1214308_3	926569.ANT_15290	4.038e-17	91.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1214308_4	1423807.BACO01000035_gene974	5.693e-12	78.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,4HA7V@91061|Bacilli,3FB9J@33958|Lactobacillaceae	91061|Bacilli	S	Serine hydrolase (FSH1)	yfhR3	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
HSJS2_k127_1214308_0	243164.DET0194	1.314e-211	672.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,34CK0@301297|Dehalococcoidia	301297|Dehalococcoidia	J	leucyl-tRNA aminoacylation	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
HSJS2_k127_1217547_1	555088.DealDRAFT_1973	7.884e-12	68.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,42JK9@68298|Syntrophomonadaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HSJS2_k127_1217547_0	383372.Rcas_0855	4.154e-76	285.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi,3758F@32061|Chloroflexia	32061|Chloroflexia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HSJS2_k127_1220580_1	383372.Rcas_4390	3.865e-66	239.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
HSJS2_k127_1220580_4	926569.ANT_20740	1.084e-31	134.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS2_k127_1220580_0	1128421.JAGA01000002_gene1728	1.049e-97	331.0	COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HSJS2_k127_1220580_2	1382356.JQMP01000003_gene2529	6.569e-66	242.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi,27XNR@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HSJS2_k127_1220580_3	357808.RoseRS_3116	1.222e-32	136.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,375G8@32061|Chloroflexia	32061|Chloroflexia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
HSJS2_k127_1224809_0	1382356.JQMP01000004_gene561	8.092e-77	270.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_1224809_1	485913.Krac_3076	1.558e-28	122.0	COG1670@1|root,COG1670@2|Bacteria,2G76C@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HSJS2_k127_1239623_1	1172180.KB911777_gene1741	2.845e-32	132.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1239623_3	706587.Desti_3193	1.387e-11	72.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
HSJS2_k127_1239623_0	56107.Cylst_2613	4.879e-74	263.0	COG1520@1|root,COG1520@2|Bacteria,1GDEQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
HSJS2_k127_1239623_4	96561.Dole_1550	0.0006014	51.0	COG1028@1|root,COG1545@1|root,COG3255@1|root,COG3425@1|root,COG1028@2|Bacteria,COG1545@2|Bacteria,COG3255@2|Bacteria,COG3425@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria,2MHRA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,MaoC_dehydrat_N,MaoC_dehydratas,OB_aCoA_assoc,SCP2,adh_short
HSJS2_k127_1239623_2	398720.MED217_02585	9.136e-30	121.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HYW2@117743|Flavobacteriia,2XJ20@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HSJS2_k127_1251305_5	243164.DET1375	5.898e-23	101.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,34D96@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HSJS2_k127_1251305_0	1382306.JNIM01000001_gene1396	4.926e-145	480.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HSJS2_k127_1251305_2	1313172.YM304_11550	6.082e-73	260.0	COG2035@1|root,COG2035@2|Bacteria,2I8HU@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
HSJS2_k127_1251305_1	101510.RHA1_ro11036	1.174e-81	289.0	COG1028@1|root,COG1028@2|Bacteria,2GIRG@201174|Actinobacteria,4FU04@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS2_k127_1251305_3	1306174.JODP01000002_gene5748	4.098e-53	198.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
HSJS2_k127_1251305_4	552811.Dehly_0243	1.055e-52	195.0	COG0062@1|root,COG0062@2|Bacteria,2G8T6@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	-	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
HSJS2_k127_1253718_4	1120973.AQXL01000122_gene191	7.559e-22	109.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,278QJ@186823|Alicyclobacillaceae	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	dppA_1	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HSJS2_k127_1253718_3	1382306.JNIM01000001_gene780	8.115e-33	134.0	2DN66@1|root,32VSD@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
HSJS2_k127_1253718_6	1123248.KB893327_gene770	4.941e-13	79.0	COG3832@1|root,COG3832@2|Bacteria,4NQXU@976|Bacteroidetes,1IXTD@117747|Sphingobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_1253718_1	593907.Celgi_2353	5.333e-85	298.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4F0PC@85016|Cellulomonadaceae	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
HSJS2_k127_1253718_2	345341.KUTG_07033	1.734e-66	239.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4EEIC@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_1253718_5	1380390.JIAT01000010_gene3397	8.48e-19	91.0	COG3631@1|root,COG3631@2|Bacteria,2IGEH@201174|Actinobacteria,4CR0V@84995|Rubrobacteria	84995|Rubrobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HSJS2_k127_1253718_0	525904.Tter_1474	1.598e-138	449.0	COG0667@1|root,COG0673@1|root,COG0667@2|Bacteria,COG0673@2|Bacteria,2NP86@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase family, NAD-binding Rossmann fold	strT	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,GFO_IDH_MocA
HSJS2_k127_126137_2	479434.Sthe_2425	8.529e-19	92.0	COG1565@1|root,COG1565@2|Bacteria,2G8NS@200795|Chloroflexi,27Y3B@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
HSJS2_k127_126137_1	42256.RradSPS_1124	7.252e-19	97.0	COG1225@1|root,COG1225@2|Bacteria,2HG0X@201174|Actinobacteria,4CTWJ@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS2_k127_126137_0	1121441.AUCX01000009_gene2552	2.605e-28	120.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2M82B@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
HSJS2_k127_126137_3	452637.Oter_0710	2.897e-18	95.0	COG2068@1|root,COG2068@2|Bacteria,46TBW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HSJS2_k127_126137_4	1211115.ALIQ01000026_gene703	4.27e-09	65.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria,3N9RX@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	MA20_22080	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HSJS2_k127_1273500_3	479434.Sthe_2445	1.209e-45	177.0	COG0697@1|root,COG0697@2|Bacteria,2G8R9@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS2_k127_1273500_2	525368.HMPREF0591_0025	2.054e-58	217.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria,23B3Y@1762|Mycobacteriaceae	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1273500_0	1128421.JAGA01000002_gene1133	1.979e-99	335.0	COG0709@1|root,COG0709@2|Bacteria,2NNUD@2323|unclassified Bacteria	2|Bacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
HSJS2_k127_1273500_4	1123371.ATXH01000010_gene705	1.883e-41	164.0	COG1056@1|root,COG1056@2|Bacteria,2GI84@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	cytidyltransferase-related domain	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	-
HSJS2_k127_1273500_1	1125863.JAFN01000001_gene1730	2.177e-63	235.0	COG3635@1|root,COG3635@2|Bacteria,1R2SD@1224|Proteobacteria,42NR6@68525|delta/epsilon subdivisions,2WJZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TIGRFAM phosphonopyruvate decarboxylase-related protein	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
HSJS2_k127_1277093_11	457429.ABJI02000033_gene5802	8.472e-08	55.0	COG1062@1|root,COG1062@2|Bacteria,2HDC7@201174|Actinobacteria	201174|Actinobacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1277093_5	981369.JQMJ01000004_gene3750	2.849e-33	138.0	COG0288@1|root,COG0288@2|Bacteria,2II5B@201174|Actinobacteria,2NIX3@228398|Streptacidiphilus	201174|Actinobacteria	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HSJS2_k127_1277093_9	1157640.AQWO01000001_gene6265	6.834e-11	71.0	COG1714@1|root,COG1714@2|Bacteria,2GZE9@201174|Actinobacteria	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HSJS2_k127_1277093_6	485914.Hmuk_3069	3.147e-26	113.0	COG1714@1|root,arCOG03633@2157|Archaea,2Y0FR@28890|Euryarchaeota,23XUM@183963|Halobacteria	183963|Halobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HSJS2_k127_1277093_7	485913.Krac_8885	3.259e-26	111.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HSJS2_k127_1277093_0	266117.Rxyl_0133	6.052e-223	717.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HSJS2_k127_1277093_2	316274.Haur_2844	4.941e-98	328.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia	200795|Chloroflexi	P	ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HSJS2_k127_1277093_3	1229780.BN381_130287	7.21e-77	271.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,3UXDF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.35	ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00243,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
HSJS2_k127_1277093_1	316274.Haur_2846	6.204e-109	367.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HSJS2_k127_1277093_8	1128421.JAGA01000003_gene3082	9.89e-19	92.0	COG0735@1|root,COG0735@2|Bacteria,2NQ2N@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS2_k127_1277093_4	867845.KI911784_gene1619	2.322e-65	243.0	COG0477@1|root,COG0477@2|Bacteria,2G856@200795|Chloroflexi,375QC@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_1277093_10	926560.KE387023_gene2288	4.992e-08	58.0	COG1960@1|root,COG1960@2|Bacteria,1WMGQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_1298818_11	1280953.HOC_13119	1.079e-30	135.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	GntR,HTH_18,LacI,Peripla_BP_1,Peripla_BP_3
HSJS2_k127_1298818_8	1469245.JFBG01000008_gene751	4.409e-53	196.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria,1SVTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HSJS2_k127_1298818_1	479434.Sthe_1801	2.953e-152	493.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS2_k127_1298818_3	1382356.JQMP01000001_gene828	8.938e-131	432.0	COG0113@1|root,COG0113@2|Bacteria,2G5QT@200795|Chloroflexi,27XTX@189775|Thermomicrobia	189775|Thermomicrobia	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HSJS2_k127_1298818_4	1128421.JAGA01000001_gene2427	4.993e-130	433.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2NPBQ@2323|unclassified Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	hemD	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K02303,ko:K13542,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755,iJN678.hemD	HEM4,TP_methylase
HSJS2_k127_1298818_6	1382356.JQMP01000001_gene830	3.464e-71	251.0	COG0181@1|root,COG0181@2|Bacteria,2G6JU@200795|Chloroflexi,27Y7G@189775|Thermomicrobia	189775|Thermomicrobia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	-	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
HSJS2_k127_1298818_7	469383.Cwoe_5878	2.661e-67	248.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CPKE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HSJS2_k127_1298818_10	552811.Dehly_0452	3.287e-37	151.0	COG1648@1|root,COG1648@2|Bacteria,2G753@200795|Chloroflexi	200795|Chloroflexi	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
HSJS2_k127_1298818_9	243233.MCA1802	5.377e-38	164.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,1XGDV@135618|Methylococcales	135618|Methylococcales	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
HSJS2_k127_1298818_0	469383.Cwoe_5531	5.666e-193	619.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HSJS2_k127_1298818_2	326424.FRAAL2108	5.348e-144	462.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4ERIE@85013|Frankiales	201174|Actinobacteria	EH	Sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HSJS2_k127_1298818_5	106370.Francci3_1342	4.025e-127	415.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4ERC4@85013|Frankiales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
HSJS2_k127_1299527_3	3827.XP_004511690.1	1.354e-06	59.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37PZP@33090|Viridiplantae,3GFZZ@35493|Streptophyta,4JFX1@91835|fabids	35493|Streptophyta	O	Belongs to the peptidase M10A family	-	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0043170,GO:0044238,GO:0044425,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
HSJS2_k127_1299527_1	671143.DAMO_1861	1.131e-115	383.0	COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HSJS2_k127_1299527_0	671143.DAMO_1857	9.847e-188	614.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2NNXI@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_2160,iPC815.YPO2428	B3_4,B5,FDX-ACB,tRNA_bind
HSJS2_k127_1299527_2	479434.Sthe_2516	1.855e-79	275.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HSJS2_k127_1302402_0	357808.RoseRS_3952	5.299e-28	131.0	COG0477@1|root,COG0477@2|Bacteria,2GA6R@200795|Chloroflexi,3782R@32061|Chloroflexia	32061|Chloroflexia	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_1302402_1	349161.Dred_3081	1.784e-25	121.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,2627P@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
HSJS2_k127_1302402_2	292459.STH124	4.259e-22	106.0	COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia	186801|Clostridia	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1313781_0	479434.Sthe_0585	1.873e-28	121.0	COG3764@1|root,COG3764@2|Bacteria,2G77W@200795|Chloroflexi,27YHD@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
HSJS2_k127_1313781_1	585531.HMPREF0063_11575	1.125e-24	111.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4DPVS@85009|Propionibacteriales	201174|Actinobacteria	K	ECF sigma factor	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS2_k127_1313781_2	187272.Mlg_2394	1.136e-10	74.0	COG2304@1|root,COG2304@2|Bacteria,1P8UT@1224|Proteobacteria	1224|Proteobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
HSJS2_k127_1317000_1	186497.PF1931	1.101e-15	87.0	COG0467@1|root,arCOG01171@2157|Archaea,2XTU3@28890|Euryarchaeota,242JC@183968|Thermococci	183968|Thermococci	T	Belongs to the UPF0273 family	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
HSJS2_k127_1317000_0	1540221.JQNI01000002_gene1131	8.484e-34	139.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HSJS2_k127_1317000_2	234267.Acid_2155	5.03e-10	66.0	2E65M@1|root,330UB@2|Bacteria	2|Bacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS2_k127_1329531_2	4529.ORUFI01G43170.1	6.391e-42	160.0	COG0216@1|root,KOG2726@2759|Eukaryota,37SSY@33090|Viridiplantae,3G9BB@35493|Streptophyta,3KTXR@4447|Liliopsida,3I9YQ@38820|Poales	35493|Streptophyta	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
HSJS2_k127_1329531_0	1121396.KB892935_gene3861	1.312e-51	203.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_1329531_4	203124.Tery_1121	1.39e-16	83.0	COG2127@1|root,COG2127@2|Bacteria,1G6M6@1117|Cyanobacteria,1HBNB@1150|Oscillatoriales	1117|Cyanobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
HSJS2_k127_1329531_3	1323361.JPOC01000036_gene4077	5.104e-26	115.0	COG3871@1|root,COG3871@2|Bacteria,2I2QZ@201174|Actinobacteria,4G9FN@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_1329531_1	83406.HDN1F_24210	2.585e-42	166.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1J5UZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HSJS2_k127_1335403_1	479434.Sthe_3385	2.394e-107	361.0	COG1062@1|root,COG1062@2|Bacteria,2G7KZ@200795|Chloroflexi,27XUS@189775|Thermomicrobia	189775|Thermomicrobia	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS2_k127_1335403_2	471853.Bcav_2761	3.438e-72	258.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
HSJS2_k127_1335403_0	479434.Sthe_0227	2.332e-175	565.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HSJS2_k127_1347571_2	584708.Apau_1789	1.681e-25	115.0	COG2045@1|root,COG2045@2|Bacteria,3TB1D@508458|Synergistetes	508458|Synergistetes	H	Belongs to the ComB family	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
HSJS2_k127_1347571_1	322710.Avin_41440	1.521e-52	195.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HSJS2_k127_1347571_0	552811.Dehly_0004	2.096e-55	199.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi,34CQ3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HSJS2_k127_1347958_1	446469.Sked_23610	8.976e-74	262.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HSJS2_k127_1347958_2	309801.trd_0999	4.767e-56	202.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi,27Y81@189775|Thermomicrobia	189775|Thermomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HSJS2_k127_1347958_3	1178540.BA70_07045	1.004e-50	190.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,1ZAZF@1386|Bacillus	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HSJS2_k127_1347958_0	324602.Caur_3569	7.734e-81	279.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi,375B7@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HSJS2_k127_1347958_5	1167006.UWK_02081	1.41e-32	137.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2WQ6V@28221|Deltaproteobacteria,2MIDG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HSJS2_k127_1347958_4	255470.cbdbA314	2.907e-33	136.0	COG0743@1|root,COG0743@2|Bacteria,2G5RB@200795|Chloroflexi,34CVA@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
HSJS2_k127_1362798_0	937777.Deipe_1727	3.886e-112	370.0	COG0667@1|root,COG0667@2|Bacteria,1WJFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS2_k127_1362798_2	1455608.JDTH01000011_gene2312	2.167e-49	188.0	COG0596@1|root,arCOG01648@2157|Archaea,2XVTE@28890|Euryarchaeota,23TCW@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS2_k127_1362798_1	479434.Sthe_2506	8.705e-58	220.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_1362798_3	1713.JOFV01000008_gene3203	1.475e-16	89.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria,4F2JQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HSJS2_k127_1367818_3	448385.sce7526	1.485e-11	65.0	COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,43BB8@68525|delta/epsilon subdivisions,2X6QE@28221|Deltaproteobacteria,2YVUR@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
HSJS2_k127_1367818_0	1260251.SPISAL_00250	3.476e-94	321.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
HSJS2_k127_1367818_1	1123024.AUII01000002_gene1084	3.077e-41	167.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2I75H@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_1367818_2	1123024.AUII01000002_gene1084	4.858e-38	156.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2I75H@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_1383165_0	926569.ANT_10740	1.966e-70	258.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
HSJS2_k127_1383165_1	1037409.BJ6T_56240	8.137e-61	228.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc,Hydrolase_4,Trans_reg_C
HSJS2_k127_1383165_2	1206731.BAGB01000047_gene5231	1.153e-17	88.0	COG0599@1|root,COG0599@2|Bacteria,2IM8G@201174|Actinobacteria,4G8MT@85025|Nocardiaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
HSJS2_k127_1385953_1	471853.Bcav_2258	7.56e-50	191.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	MA20_27720	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_1385953_0	485913.Krac_2496	6.56e-159	521.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS2_k127_1385953_2	1122247.C731_1921	8.167e-19	95.0	COG3178@1|root,COG3178@2|Bacteria,2GN8T@201174|Actinobacteria,23F8B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
HSJS2_k127_1406767_0	908337.HMPREF9257_1778	2.924e-52	187.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,27DRH@186827|Aerococcaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HSJS2_k127_1406767_1	1386089.N865_19290	1.181e-46	175.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria,4FIIB@85021|Intrasporangiaceae	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
HSJS2_k127_1406767_2	926560.KE387027_gene366	1.255e-38	156.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS2_k127_1406942_3	1429916.X566_16090	1.088e-07	56.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,3JUD7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS2_k127_1406942_0	1123023.JIAI01000003_gene2846	7.924e-67	239.0	COG1028@1|root,COG1028@2|Bacteria,2H8QY@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS2_k127_1406942_1	311424.DhcVS_464	1.717e-32	133.0	COG1670@1|root,COG1670@2|Bacteria,2GAMB@200795|Chloroflexi,34CRJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HSJS2_k127_1406942_2	485913.Krac_12558	1.661e-30	130.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
HSJS2_k127_1406942_4	926550.CLDAP_05610	0.0006068	47.0	COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
HSJS2_k127_142286_1	882083.SacmaDRAFT_2036	2.207e-68	244.0	COG1028@1|root,COG1028@2|Bacteria,2H0SM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100,1.1.1.401	ko:K00059,ko:K21883	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11339,R11671	RC00029,RC00089,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HSJS2_k127_142286_0	1382356.JQMP01000003_gene2001	8.297e-93	324.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi,27Y0D@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
HSJS2_k127_142286_2	1146883.BLASA_1529	2.709e-19	92.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4EUB2@85013|Frankiales	201174|Actinobacteria	J	Amidase	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
HSJS2_k127_1453167_1	398578.Daci_0143	2.14e-45	170.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VKM4@28216|Betaproteobacteria,4ACK9@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_1453167_2	118161.KB235922_gene3012	2.321e-32	143.0	COG0775@1|root,COG0775@2|Bacteria,1GAY9@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	pfs	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HSJS2_k127_1453167_0	479434.Sthe_3003	7.159e-73	262.0	COG1804@1|root,COG1804@2|Bacteria,2GABR@200795|Chloroflexi,27XHH@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_1455396_6	1437606.BBOH_0281	2.451e-12	70.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
HSJS2_k127_1455396_1	472759.Nhal_2851	2.096e-132	437.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXUS@135613|Chromatiales	135613|Chromatiales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HSJS2_k127_1455396_4	797114.C475_04009	3.184e-23	108.0	COG2259@1|root,arCOG02861@2157|Archaea,2XWFV@28890|Euryarchaeota,23UNF@183963|Halobacteria	183963|Halobacteria	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
HSJS2_k127_1455396_0	1410634.JHVD01000027_gene1655	3.754e-298	940.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
HSJS2_k127_1455396_2	1457250.BBMO01000001_gene1882	6.074e-63	232.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWGR@28890|Euryarchaeota,23VES@183963|Halobacteria	183963|Halobacteria	E	COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HSJS2_k127_1455396_5	1957.JODX01000007_gene2136	1.995e-18	94.0	28JCJ@1|root,2Z977@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
HSJS2_k127_1455396_3	1227453.C444_19092	1.208e-42	166.0	arCOG08999@1|root,arCOG08999@2157|Archaea,2XYVR@28890|Euryarchaeota,23X8E@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1470803_7	1158150.KB906241_gene506	1.46e-10	74.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1SDVD@1236|Gammaproteobacteria,1WZPY@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
HSJS2_k127_1470803_4	196367.JNFG01000214_gene1275	1.378e-50	189.0	COG0596@1|root,COG0596@2|Bacteria,1N3G3@1224|Proteobacteria,2WH3B@28216|Betaproteobacteria,1KIHJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_1470803_1	1303518.CCALI_01253	4.971e-68	249.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
HSJS2_k127_1470803_0	502025.Hoch_5408	1.017e-172	575.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YTZK@29|Myxococcales	28221|Deltaproteobacteria	CE	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
HSJS2_k127_1470803_3	479434.Sthe_0937	1.329e-53	197.0	COG0461@1|root,COG0461@2|Bacteria,2G6RG@200795|Chloroflexi,27YBT@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HSJS2_k127_1470803_6	1382356.JQMP01000003_gene2513	2.48e-26	118.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,27Y6Z@189775|Thermomicrobia	189775|Thermomicrobia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HSJS2_k127_1470803_2	370438.PTH_2838	1.884e-59	219.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,260W6@186807|Peptococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HSJS2_k127_1470803_5	765420.OSCT_2500	3.743e-48	183.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS2_k127_1470803_9	357808.RoseRS_4388	1.27e-05	51.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi,375WU@32061|Chloroflexia	32061|Chloroflexia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1474030_7	926554.KI912622_gene1031	2.049e-30	127.0	COG1253@1|root,COG1253@2|Bacteria,1WI7Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HSJS2_k127_1474030_2	561175.KB894094_gene1747	3.869e-61	223.0	COG1011@1|root,COG1011@2|Bacteria,2I3IU@201174|Actinobacteria,4EP7A@85012|Streptosporangiales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HSJS2_k127_1474030_3	1121377.KB906410_gene592	2.509e-49	186.0	COG2897@1|root,COG2897@2|Bacteria,1WI0D@1297|Deinococcus-Thermus	2|Bacteria	P	Sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HSJS2_k127_1474030_6	634497.HAH_1573	5.655e-37	156.0	COG0477@1|root,arCOG00130@2157|Archaea,2XT6G@28890|Euryarchaeota,23SC5@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_1474030_5	1449353.JQMQ01000004_gene6252	1.206e-44	172.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_1474030_4	391625.PPSIR1_20059	2.363e-45	174.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,2Z0S2@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
HSJS2_k127_1474030_0	1121423.JONT01000009_gene1507	4.408e-80	284.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,24EUD@186801|Clostridia,267G2@186807|Peptococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS2_k127_1474030_1	1366050.N234_25195	5.561e-76	262.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VN7W@28216|Betaproteobacteria,1K9NU@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HSJS2_k127_1477058_4	113395.AXAI01000002_gene5239	1.344e-30	141.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria	1224|Proteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HSJS2_k127_1477058_0	525904.Tter_1201	6.144e-167	551.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS2_k127_1477058_1	867845.KI911784_gene1197	1.195e-135	453.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,376DV@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS2_k127_1477058_3	1312959.KI914645_gene925	1.88e-40	157.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
HSJS2_k127_1477058_5	653733.Selin_2341	2.811e-08	63.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_3
HSJS2_k127_1477058_2	1333998.M2A_1717	1.389e-97	329.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2TTR7@28211|Alphaproteobacteria,4BRF4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_1479536_1	216594.MMAR_3505	9.758e-43	173.0	COG0596@1|root,COG2114@1|root,COG0596@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria,232FZ@1762|Mycobacteriaceae	201174|Actinobacteria	IT	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
HSJS2_k127_1479536_0	1366050.N234_21575	7.07e-96	321.0	COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,2W9FY@28216|Betaproteobacteria,1K7F7@119060|Burkholderiaceae	28216|Betaproteobacteria	S	alpha/beta hydrolase fold	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HSJS2_k127_1479536_2	314285.KT71_02522	1.265e-08	57.0	COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,1RSIP@1236|Gammaproteobacteria,1J4I2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
HSJS2_k127_1501199_2	1040989.AWZU01000065_gene6530	1.091e-59	214.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria,3JT1R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
HSJS2_k127_1501199_1	1380387.JADM01000002_gene2121	6.848e-69	244.0	COG0346@1|root,COG0346@2|Bacteria,1MW8Z@1224|Proteobacteria,1SPM3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
HSJS2_k127_1501199_3	1133849.O3I_016820	1.467e-43	171.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,4G938@85025|Nocardiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HSJS2_k127_1501199_4	1120965.AUBV01000016_gene94	1.023e-25	111.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
HSJS2_k127_1501199_0	1239962.C943_02139	1.659e-77	274.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HSJS2_k127_1504213_1	572544.Ilyop_1697	5.813e-28	115.0	COG1200@1|root,COG1200@2|Bacteria,378RT@32066|Fusobacteria	32066|Fusobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HSJS2_k127_1504213_2	657322.FPR_17740	8.923e-21	99.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HSJS2_k127_1504213_3	525904.Tter_1653	6.612e-14	76.0	COG0227@1|root,COG0227@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HSJS2_k127_1504213_0	1235279.C772_00573	1.354e-100	348.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,26D3P@186818|Planococcaceae	91061|Bacilli	S	Dak1_2	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
HSJS2_k127_1514874_1	1123504.JQKD01000012_gene1257	2.819e-61	229.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria,4AH2J@80864|Comamonadaceae	28216|Betaproteobacteria	C	CoA-transferase family III	bbsE	-	2.8.3.15	ko:K07543	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_1514874_0	1429916.X566_22120	3.721e-110	368.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria,3JX5E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HSJS2_k127_1514874_2	392499.Swit_3652	9.293e-20	101.0	COG1545@1|root,COG1545@2|Bacteria,1N7HH@1224|Proteobacteria,2UFFB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_1540199_3	158189.SpiBuddy_2517	3.963e-25	121.0	COG0747@1|root,COG0747@2|Bacteria,2J86R@203691|Spirochaetes	203691|Spirochaetes	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HSJS2_k127_1540199_0	502025.Hoch_5710	2.626e-143	484.0	COG0490@1|root,COG1226@1|root,COG4651@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,2YX01@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
HSJS2_k127_1540199_4	391589.RGAI101_2409	1.628e-13	85.0	COG1359@1|root,COG1359@2|Bacteria,1NBVY@1224|Proteobacteria,2UM51@28211|Alphaproteobacteria,2P3MG@2433|Roseobacter	28211|Alphaproteobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HSJS2_k127_1540199_2	1232683.ADIMK_3343	5.087e-36	140.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057	-	ko:K03406,ko:K06886	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Bac_globin
HSJS2_k127_1540199_1	1232683.ADIMK_3344	2.057e-116	386.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,1S3UK@1236|Gammaproteobacteria,468QZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
HSJS2_k127_1541104_4	1434325.AZQN01000001_gene2	0.0002559	44.0	COG0639@1|root,COG0639@2|Bacteria,4NFPU@976|Bacteroidetes,47MX3@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
HSJS2_k127_1541104_1	1089548.KI783301_gene2787	5.015e-64	241.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,3WG2H@539002|Bacillales incertae sedis	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HSJS2_k127_1541104_2	886293.Sinac_2964	4.965e-59	228.0	COG3622@1|root,COG3622@2|Bacteria,2J4Z5@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HSJS2_k127_1541104_0	552811.Dehly_0973	8.208e-182	591.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi,34CP1@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
HSJS2_k127_1541104_3	1394178.AWOO02000015_gene7055	2.21e-06	49.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EHHR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1575373_1	1457250.BBMO01000002_gene2682	3.139e-24	120.0	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,23SV0@183963|Halobacteria	183963|Halobacteria	L	exporters of the RND superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
HSJS2_k127_1575373_2	1298863.AUEP01000020_gene3609	2.189e-14	78.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4DSW5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1575373_0	329726.AM1_6085	1.044e-26	113.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria	1117|Cyanobacteria	K	ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
HSJS2_k127_1577336_4	1532557.JL37_09570	7.846e-27	119.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria	1224|Proteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1577336_2	42256.RradSPS_2237	1.724e-53	198.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CQAE@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_1577336_8	62977.ACIAD1223	5.419e-05	51.0	COG3324@1|root,COG3324@2|Bacteria,1N3R0@1224|Proteobacteria	1224|Proteobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_1577336_3	879212.DespoDRAFT_01339	4.344e-42	159.0	COG2461@1|root,COG2461@2|Bacteria,1QX14@1224|Proteobacteria,43EIT@68525|delta/epsilon subdivisions,2X8HQ@28221|Deltaproteobacteria	1224|Proteobacteria	S	TIGRFAM PAS domain S-box	-	-	-	-	-	-	-	-	-	-	-	-	PAS
HSJS2_k127_1577336_1	665577.JH993790_gene5212	6.506e-73	276.0	COG1804@1|root,COG1804@2|Bacteria,2IB9E@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1577336_0	566461.SSFG_06732	1.683e-95	327.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1577336_6	395963.Bind_2065	1.659e-11	71.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,2U8HG@28211|Alphaproteobacteria,3NBEH@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	DinB family	dinB	-	-	-	-	-	-	-	-	-	-	-	DinB
HSJS2_k127_1577336_7	530564.Psta_0758	1.572e-10	72.0	COG2318@1|root,COG2318@2|Bacteria,2J1JI@203682|Planctomycetes	203682|Planctomycetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
HSJS2_k127_1577336_5	479434.Sthe_1630	4.519e-20	93.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
HSJS2_k127_1602987_0	1128421.JAGA01000003_gene2751	1.521e-178	567.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HSJS2_k127_1602987_1	1285586.H131_07773	1.544e-14	79.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3IX0A@400634|Lysinibacillus	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HSJS2_k127_1620569_4	1127134.NOCYR_1573	4.118e-12	71.0	2EQM1@1|root,33I6Z@2|Bacteria,2GXMH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HSJS2_k127_1620569_1	324602.Caur_1278	7.016e-45	182.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	ntcA	-	-	ko:K01420,ko:K10716,ko:K10914,ko:K16922	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko01002,ko02000,ko03000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	HTH_Crp_2,cNMP_binding
HSJS2_k127_1620569_3	710686.Mycsm_01705	8.222e-20	98.0	COG1309@1|root,COG1309@2|Bacteria,2IGXP@201174|Actinobacteria,238UJ@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	-	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K22295	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
HSJS2_k127_1620569_2	1379698.RBG1_1C00001G1780	2.763e-21	97.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HSJS2_k127_1620569_0	670307.HYPDE_23323	1.492e-270	853.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TU9X@28211|Alphaproteobacteria,3N6DP@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
HSJS2_k127_1625179_2	1121945.ATXS01000001_gene2504	2.652e-37	162.0	COG4948@1|root,arCOG01168@2157|Archaea,2XU6X@28890|Euryarchaeota,23SAR@183963|Halobacteria	183963|Halobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
HSJS2_k127_1625179_1	926550.CLDAP_30590	1.619e-81	284.0	COG1575@1|root,COG1575@2|Bacteria,2G5ZC@200795|Chloroflexi	200795|Chloroflexi	H	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HSJS2_k127_1625179_0	1356854.N007_20610	3e-127	417.0	COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli	91061|Bacilli	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_1625179_3	479434.Sthe_3023	2.482e-15	79.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
HSJS2_k127_1630572_0	323097.Nham_0662	3.924e-170	552.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,3JVEU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Reductase C-terminal	-	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C,Rieske
HSJS2_k127_1630572_1	880073.Calab_3022	4.697e-154	501.0	COG1012@1|root,COG1012@2|Bacteria,2NQRG@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	gabD1	GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009060,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044464,GO:0045333,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79	ko:K00135,ko:K08324	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.gabD,iECUMN_1333.ECUMN_1793,iJN678.gabD	Aldedh
HSJS2_k127_1630572_6	1227497.C491_12005	0.000241	51.0	COG0589@1|root,COG0633@1|root,arCOG00449@2157|Archaea,arCOG02844@2157|Archaea,2XU1P@28890|Euryarchaeota,23SZU@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Usp
HSJS2_k127_1630572_3	867845.KI911784_gene79	2.888e-23	105.0	COG0783@1|root,COG0783@2|Bacteria,2G9YH@200795|Chloroflexi,3779J@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
HSJS2_k127_1630572_2	344747.PM8797T_15536	9.537e-67	243.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C
HSJS2_k127_1630572_4	420324.KI911952_gene3302	3.861e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,1JT9M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_1630572_5	1120949.KB903294_gene3786	3.174e-13	70.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4D9MN@85008|Micromonosporales	201174|Actinobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
HSJS2_k127_1644135_2	1121927.GOHSU_02_01800	6.261e-29	129.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4GH8E@85026|Gordoniaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_1644135_0	1207063.P24_05209	2.113e-179	572.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TU67@28211|Alphaproteobacteria,2JRJM@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HSJS2_k127_1644135_1	861299.J421_0542	2.057e-71	250.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
HSJS2_k127_1644135_4	1245475.ANAE01000208_gene2235	3.674e-06	58.0	COG2030@1|root,COG2030@2|Bacteria,2GXE5@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS2_k127_1644135_3	485913.Krac_11356	2.365e-20	94.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HSJS2_k127_1653347_4	195105.CN97_16755	1.952e-23	107.0	28HWH@1|root,2Z82E@2|Bacteria,1MUF7@1224|Proteobacteria,2TV8Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1653347_6	56780.SYN_02900	2.044e-10	71.0	COG5553@1|root,COG5553@2|Bacteria,1NI0U@1224|Proteobacteria,43160@68525|delta/epsilon subdivisions,2WWEA@28221|Deltaproteobacteria,2MS6U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1653347_0	1101190.ARWB01000001_gene3908	2.918e-76	271.0	COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,2TTIQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the desulfonation of aliphatic sulfonates	ssuD	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HSJS2_k127_1653347_1	1380390.JIAT01000013_gene299	3.504e-29	124.0	COG1403@1|root,COG1403@2|Bacteria,2GV0W@201174|Actinobacteria,4CQF2@84995|Rubrobacteria	84995|Rubrobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
HSJS2_k127_1653347_2	387092.NIS_0278	2.169e-26	111.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,43B6G@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HSJS2_k127_1653347_3	1288484.APCS01000013_gene914	3.745e-25	110.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
HSJS2_k127_1653347_5	525904.Tter_1943	4.688e-13	81.0	2DBT9@1|root,32TY2@2|Bacteria,2NRI3@2323|unclassified Bacteria	2|Bacteria	S	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	-
HSJS2_k127_1654860_0	1507.HMPREF0262_03516	4.102e-60	224.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,36DC9@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HSJS2_k127_1654860_1	1303518.CCALI_00819	6.905e-14	77.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HSJS2_k127_1654860_2	290397.Adeh_2440	5.78e-07	54.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
HSJS2_k127_1655995_2	1121087.AUCK01000007_gene1740	2.149e-10	65.0	2E175@1|root,32WMX@2|Bacteria,1V5R3@1239|Firmicutes,4HI53@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1655995_1	546414.Deide_21420	3.443e-31	130.0	COG1158@1|root,COG1158@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HSJS2_k127_1655995_0	208444.JNYY01000015_gene3841	0.0	1217.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4E1A0@85010|Pseudonocardiales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB2	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HSJS2_k127_166527_0	644966.Tmar_1056	1.507e-200	642.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,25EG8@186801|Clostridia,3WDQS@538999|Clostridiales incertae sedis	186801|Clostridia	KL	PFAM Helicase conserved C-terminal domain	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
HSJS2_k127_166527_2	479434.Sthe_1663	2.451e-38	160.0	COG3359@1|root,COG3359@2|Bacteria	2|Bacteria	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
HSJS2_k127_166527_1	472759.Nhal_3623	1.562e-54	213.0	COG1404@1|root,COG1404@2|Bacteria,1RDZC@1224|Proteobacteria,1S91S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HSJS2_k127_166527_3	479431.Namu_1211	4.241e-07	55.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4EX79@85013|Frankiales	201174|Actinobacteria	K	Sigma-70, region 4	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HSJS2_k127_166662_1	316274.Haur_1194	8.595e-62	222.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,376AI@32061|Chloroflexia	32061|Chloroflexia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HSJS2_k127_166662_0	1382356.JQMP01000004_gene63	5.026e-152	499.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia	189775|Thermomicrobia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HSJS2_k127_1667094_2	247490.KSU1_D0327	4.509e-29	124.0	COG0852@1|root,COG0852@2|Bacteria,2IZCK@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HSJS2_k127_1667094_0	243164.DET0926	3.636e-108	364.0	COG0649@1|root,COG0649@2|Bacteria,2G5JF@200795|Chloroflexi,34D5Q@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
HSJS2_k127_1667094_1	768704.Desmer_3720	2.983e-85	297.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,25E6Z@186801|Clostridia,260SW@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HSJS2_k127_1667094_3	1386089.N865_18435	8.128e-20	96.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria,4FG07@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
HSJS2_k127_1667094_4	1403313.AXBR01000026_gene5204	2.904e-17	91.0	COG0839@1|root,COG0839@2|Bacteria,1V48R@1239|Firmicutes,4HJAV@91061|Bacilli,1ZFW1@1386|Bacillus	91061|Bacilli	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HSJS2_k127_1704328_1	1238182.C882_3798	7.206e-35	137.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria,2JZ9I@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
HSJS2_k127_1704328_0	1408224.SAMCCGM7_c6619	4.652e-66	243.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,4BAPG@82115|Rhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Guanylate_cyc,Hydrolase_4,Trans_reg_C
HSJS2_k127_1704328_3	710696.Intca_0369	5.203e-13	81.0	COG0596@1|root,COG1506@1|root,COG3710@1|root,COG0596@2|Bacteria,COG1506@2|Bacteria,COG3710@2|Bacteria,2HASC@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HSJS2_k127_1704328_2	1238182.C882_3798	2.777e-31	139.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria,2JZ9I@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
HSJS2_k127_1708471_1	1116369.KB890026_gene5380	1.817e-29	135.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TS14@28211|Alphaproteobacteria,43NWH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	nikA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
HSJS2_k127_1708471_0	1108045.GORHZ_060_00170	5.72e-64	237.0	COG2197@1|root,COG2197@2|Bacteria,2I9YV@201174|Actinobacteria,4GGYC@85026|Gordoniaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
HSJS2_k127_1708471_2	1502851.FG93_03414	6.992e-18	91.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	bacB	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CDO_I,Cupin_2
HSJS2_k127_1708471_3	477641.MODMU_2525	4.932e-15	78.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS2_k127_1722164_0	1136417.AZWE01000005_gene4658	1.006e-69	248.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,4DGHU@85008|Micromonosporales	201174|Actinobacteria	M	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HSJS2_k127_1722164_2	1313172.YM304_21910	1.835e-34	141.0	COG1296@1|root,COG1296@2|Bacteria	2|Bacteria	E	L-valine transmembrane transporter activity	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
HSJS2_k127_1722164_3	2074.JNYD01000023_gene1342	0.0001707	49.0	COG4392@1|root,COG4392@2|Bacteria	2|Bacteria	E	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
HSJS2_k127_1722164_1	1366050.N234_07115	4.239e-36	140.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,2VZ5F@28216|Betaproteobacteria,1KHHE@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
HSJS2_k127_1748526_0	720554.Clocl_3574	3.227e-49	189.0	COG2159@1|root,COG2159@2|Bacteria,1US2K@1239|Firmicutes,25A0W@186801|Clostridia,3WR01@541000|Ruminococcaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
HSJS2_k127_1748526_2	572478.Vdis_0835	2.982e-05	53.0	COG0454@1|root,arCOG00826@2157|Archaea,2XR3W@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_1748526_1	479434.Sthe_3505	6.095e-18	93.0	COG1011@1|root,COG1011@2|Bacteria,2G78N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HSJS2_k127_1757359_2	1089548.KI783301_gene352	8.478e-67	238.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HBTP@91061|Bacilli	91061|Bacilli	I	acyl-CoA dehydrogenase	ydbM	-	-	-	-	-	-	-	-	-	-	iYO844.BSU04520	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_1757359_3	1004149.AFOE01000020_gene3123	2.041e-05	59.0	COG1404@1|root,COG4386@1|root,COG1404@2|Bacteria,COG4386@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	bhp	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	B_lectin,CHU_C,Calx-beta
HSJS2_k127_1757359_1	479434.Sthe_2033	2.637e-75	269.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_1757359_0	1206732.BAGD01000054_gene1961	7.237e-80	276.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_1759610_1	1203554.HMPREF1476_00052	4.446e-23	102.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2VHAB@28216|Betaproteobacteria,4PQ68@995019|Sutterellaceae	28216|Betaproteobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HSJS2_k127_1759610_2	479434.Sthe_0412	6.696e-17	85.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
HSJS2_k127_1759610_0	311424.DhcVS_495	3.818e-43	165.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,34DAC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
HSJS2_k127_1759610_4	1476973.JMMB01000007_gene3215	1.27e-05	51.0	2DR0U@1|root,339Q9@2|Bacteria,1VN9R@1239|Firmicutes,24VGB@186801|Clostridia,25RU2@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HSJS2_k127_1759610_3	552811.Dehly_0545	1.633e-16	87.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,34D35@301297|Dehalococcoidia	301297|Dehalococcoidia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HSJS2_k127_1789369_3	1121428.DESHY_160029___1	1.317e-17	90.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,2624C@186807|Peptococcaceae	186801|Clostridia	H	HD superfamily hydrolase of NAD metabolism	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
HSJS2_k127_1789369_2	518766.Rmar_1819	4.642e-80	275.0	COG0501@1|root,COG0501@2|Bacteria,4PEI7@976|Bacteroidetes,1FJ5Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
HSJS2_k127_1789369_1	439235.Dalk_2665	7.204e-101	341.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_1789369_0	1394178.AWOO02000006_gene3291	1.654e-139	454.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4EH92@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_1837429_0	404589.Anae109_0474	3.304e-82	281.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
HSJS2_k127_1837429_1	439235.Dalk_5191	5.298e-72	264.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	1224|Proteobacteria	C	PFAM CoA-binding domain protein	MA20_15065	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
HSJS2_k127_1837429_3	591001.Acfer_1850	3.309e-05	55.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4H2GR@909932|Negativicutes	909932|Negativicutes	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
HSJS2_k127_1837429_2	926569.ANT_12970	1.344e-18	89.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HSJS2_k127_18502_5	1002339.HMPREF9373_1215	0.0001318	46.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,3NJ15@468|Moraxellaceae	1236|Gammaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02464,ko:K02654	ko03070,map03070	M00331	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HSJS2_k127_18502_3	42256.RradSPS_0998	2.902e-11	75.0	2DPU0@1|root,333DA@2|Bacteria,2HPPH@201174|Actinobacteria,4CR26@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_18502_4	1429046.RR21198_5528	6.079e-09	64.0	COG3467@1|root,COG3467@2|Bacteria,2IIWQ@201174|Actinobacteria,4G1S6@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_18502_2	1283299.AUKG01000002_gene4592	4.531e-21	104.0	COG1983@1|root,COG1983@2|Bacteria,2HP86@201174|Actinobacteria,4CQKI@84995|Rubrobacteria	84995|Rubrobacteria	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
HSJS2_k127_18502_0	314230.DSM3645_02368	5.892e-73	258.0	COG1319@1|root,COG1319@2|Bacteria,2IYV7@203682|Planctomycetes	203682|Planctomycetes	C	COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
HSJS2_k127_18502_1	926550.CLDAP_06500	1.225e-40	152.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HSJS2_k127_1854531_4	999415.HMPREF9943_00416	2.289e-20	100.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,3VQZY@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HSJS2_k127_1854531_0	1121920.AUAU01000004_gene898	2.119e-75	265.0	COG1131@1|root,COG1131@2|Bacteria,3Y4CW@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS2_k127_1854531_2	479434.Sthe_2670	2.114e-46	184.0	COG0842@1|root,COG0842@2|Bacteria,2G6II@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HSJS2_k127_1854531_1	469383.Cwoe_1908	9.37e-71	259.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4CS5J@84995|Rubrobacteria	84995|Rubrobacteria	O	UbiA prenyltransferase family	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
HSJS2_k127_1854531_3	1382306.JNIM01000001_gene4039	2.486e-38	156.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
HSJS2_k127_1860877_3	51337.XP_004668891.1	0.0002378	45.0	COG1804@1|root,KOG3957@2759|Eukaryota,38CWZ@33154|Opisthokonta,3BB7M@33208|Metazoa,3D0JC@33213|Bilateria,4838Z@7711|Chordata,48ZTZ@7742|Vertebrata,3JBNC@40674|Mammalia,35AGG@314146|Euarchontoglires,4Q38P@9989|Rodentia	33208|Metazoa	I	succinate-hydroxymethylglutarate CoA-transferase activity	SUGCT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008410,GO:0016740,GO:0016782,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047369	2.8.3.13	ko:K18703	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_1860877_0	331869.BAL199_08893	2.336e-164	537.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,4BQ0U@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
HSJS2_k127_1860877_1	1429916.X566_15995	2.754e-90	307.0	COG1024@1|root,COG1024@2|Bacteria,1R3U7@1224|Proteobacteria,2TV9G@28211|Alphaproteobacteria,3JU2F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS2_k127_1860877_2	631454.N177_0505	2.891e-14	75.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TTM5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate	frc	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_1867989_2	566466.NOR53_3097	5.099e-55	196.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1J8WR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793	ELFV_dehydrog,ELFV_dehydrog_N
HSJS2_k127_1867989_0	1502850.FG91_02597	6.235e-87	296.0	COG1335@1|root,COG1335@2|Bacteria,1N48X@1224|Proteobacteria,2U17G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG1335 Amidases related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HSJS2_k127_1867989_1	1071073.KI530539_gene17	3.014e-60	221.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZC1H@1386|Bacillus	91061|Bacilli	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HSJS2_k127_1867989_3	926560.KE387023_gene2318	3.148e-53	196.0	COG0601@1|root,COG0601@2|Bacteria,1WMC0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HSJS2_k127_1903917_0	1265503.KB905160_gene2777	1.725e-158	513.0	COG3119@1|root,COG3119@2|Bacteria,1NSDS@1224|Proteobacteria,1SJX8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
HSJS2_k127_1907603_3	1128421.JAGA01000002_gene1051	3.06e-40	161.0	COG0037@1|root,COG0037@2|Bacteria,2NPAZ@2323|unclassified Bacteria	2|Bacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
HSJS2_k127_1907603_8	498761.HM1_0712	7.341e-05	54.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
HSJS2_k127_1907603_7	525903.Taci_0911	8.666e-25	112.0	COG0406@1|root,COG0406@2|Bacteria,3TAZ5@508458|Synergistetes	508458|Synergistetes	G	phosphoglycerate mutase family	-	-	3.1.3.3	ko:K22305	ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130	-	R00582	RC00017	ko00000,ko00001,ko01000	-	-	-	His_Phos_1
HSJS2_k127_1907603_4	552811.Dehly_1416	4.202e-36	145.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi,34CJ6@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
HSJS2_k127_1907603_1	383372.Rcas_2999	2.072e-77	271.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi,3751X@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HSJS2_k127_1907603_2	525904.Tter_1673	4.394e-52	187.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
HSJS2_k127_1907603_5	469383.Cwoe_5865	9.569e-32	135.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HSJS2_k127_1907603_9	485913.Krac_2206	0.0004367	49.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
HSJS2_k127_1907603_0	986075.CathTA2_1034	1.845e-226	714.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HSJS2_k127_1907603_6	2074.JNYD01000022_gene1462	1.676e-30	127.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS2_k127_1911343_4	31964.CMS0126	2.544e-16	87.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria,4FMEI@85023|Microbacteriaceae	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
HSJS2_k127_1911343_3	523841.HFX_1715	3.561e-38	148.0	COG1611@1|root,arCOG02431@2157|Archaea,2XXTK@28890|Euryarchaeota,23W2P@183963|Halobacteria	183963|Halobacteria	K	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HSJS2_k127_1911343_0	1205680.CAKO01000038_gene1646	1.721e-98	335.0	COG0596@1|root,COG0596@2|Bacteria,1Q4C8@1224|Proteobacteria,2TTW5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	MA20_23630	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_1911343_2	1146883.BLASA_1617	1e-57	210.0	COG2128@1|root,COG2128@2|Bacteria,2IFER@201174|Actinobacteria,4ETKV@85013|Frankiales	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HSJS2_k127_1911343_1	1382315.JPOI01000001_gene81	4.074e-84	290.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1WEQC@129337|Geobacillus	91061|Bacilli	EU	Acetyl xylan esterase (AXE1)	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
HSJS2_k127_1917618_2	1394178.AWOO02000042_gene8755	1.301e-29	121.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4EGJ5@85012|Streptosporangiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3,Sugar_tr
HSJS2_k127_1917618_0	1056816.JAFQ01000004_gene1597	3.456e-41	161.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4FZ9I@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
HSJS2_k127_1917618_1	1464048.JNZS01000007_gene4600	1.154e-38	152.0	COG0748@1|root,COG0748@2|Bacteria,2I2TX@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Hemerythrin
HSJS2_k127_1917618_3	485913.Krac_8820	1.531e-22	102.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
HSJS2_k127_1917618_4	37919.EP51_01940	3.755e-15	78.0	COG2124@1|root,COG2124@2|Bacteria,2I2QQ@201174|Actinobacteria,4G9GV@85025|Nocardiaceae	201174|Actinobacteria	Q	Belongs to the cytochrome P450 family	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_192489_0	309801.trd_1049	2.329e-139	460.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi,27Z2G@189775|Thermomicrobia	189775|Thermomicrobia	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
HSJS2_k127_192489_1	883126.HMPREF9710_03144	3.68e-22	102.0	COG0454@1|root,COG0456@2|Bacteria,1RKFU@1224|Proteobacteria,2VUBE@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_192489_2	1336208.JADY01000024_gene3821	1.844e-11	77.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2TV0X@28211|Alphaproteobacteria,2JPU1@204441|Rhodospirillales	204441|Rhodospirillales	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HSJS2_k127_192489_4	479434.Sthe_3074	0.0004464	51.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS2_k127_192489_3	1346791.M529_17320	7.86e-08	59.0	COG0346@1|root,COG0346@2|Bacteria,1RF1Z@1224|Proteobacteria,2U7I9@28211|Alphaproteobacteria,2K6PI@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_1938207_0	399795.CtesDRAFT_PD5441	4.398e-159	510.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VNG0@28216|Betaproteobacteria,4ADU9@80864|Comamonadaceae	28216|Betaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_1938207_6	1429916.X566_07835	1.862e-35	140.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HSJS2_k127_1938207_2	1289387.AUKW01000003_gene2221	3.179e-96	322.0	COG1028@1|root,COG1028@2|Bacteria,2GWHQ@201174|Actinobacteria	201174|Actinobacteria	IQ	short-chain dehydrogenase reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HSJS2_k127_1938207_7	876269.ARWA01000001_gene2973	1.971e-32	129.0	COG5507@1|root,COG5507@2|Bacteria,1RH3Q@1224|Proteobacteria,2U9SM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM NIPSNAP family containing protein	MA20_41850	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
HSJS2_k127_1938207_1	1313172.YM304_01170	8.344e-129	425.0	COG1804@1|root,COG1804@2|Bacteria,2GKDI@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_1938207_3	1206720.BAFQ01000281_gene5906	1.58e-69	247.0	COG2220@1|root,COG2220@2|Bacteria,2IT2Z@201174|Actinobacteria,4FXF0@85025|Nocardiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_3
HSJS2_k127_1938207_8	1282360.ABAC460_10305	1.068e-14	78.0	COG0346@1|root,COG0346@2|Bacteria,1RHRF@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_1938207_5	446470.Snas_0301	3.361e-42	169.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS2_k127_1938207_4	1111728.ATYS01000001_gene2413	9.331e-61	225.0	COG2227@1|root,COG2227@2|Bacteria,1QYHT@1224|Proteobacteria,1T3QK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS2_k127_19467_2	1283299.AUKG01000001_gene1470	1.11e-16	92.0	COG0640@1|root,COG3177@1|root,COG0640@2|Bacteria,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_20,HTH_5
HSJS2_k127_19467_0	309801.trd_0085	3.459e-33	139.0	COG1853@1|root,COG1853@2|Bacteria,2G9RE@200795|Chloroflexi,27Y9A@189775|Thermomicrobia	189775|Thermomicrobia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HSJS2_k127_19467_1	479434.Sthe_3319	1.461e-25	120.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	blaB	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HSJS2_k127_2019711_3	1382306.JNIM01000001_gene3517	3.833e-08	54.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HSJS2_k127_2019711_1	552811.Dehly_1064	5.027e-63	234.0	COG2222@1|root,COG2222@2|Bacteria,2G8HU@200795|Chloroflexi,34D2X@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
HSJS2_k127_2019711_0	1128421.JAGA01000004_gene2629	8.771e-150	495.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HSJS2_k127_2019711_2	562970.Btus_0689	2.119e-57	211.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,4HB6D@91061|Bacilli,279DF@186823|Alicyclobacillaceae	91061|Bacilli	JM	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I
HSJS2_k127_2025745_1	1385518.N798_05890	3.182e-21	106.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4FF5I@85021|Intrasporangiaceae	201174|Actinobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HSJS2_k127_2025745_0	118163.Ple7327_4428	1.98e-25	111.0	2BG65@1|root,32A2Y@2|Bacteria,1G6VZ@1117|Cyanobacteria,3VJZ3@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2025745_2	1179773.BN6_34140	2.117e-08	61.0	COG2124@1|root,COG2124@2|Bacteria,2ICUT@201174|Actinobacteria,4E9ZR@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_2030863_7	1196323.ALKF01000168_gene506	3.1e-13	83.0	COG0577@1|root,COG0577@2|Bacteria,1TSP8@1239|Firmicutes,4HDWQ@91061|Bacilli,26UWM@186822|Paenibacillaceae	91061|Bacilli	V	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HSJS2_k127_2030863_2	1122919.KB905558_gene1238	2.968e-91	309.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HC59@91061|Bacilli,26SC2@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS2_k127_2030863_3	105422.BBPM01000004_gene5423	6.953e-66	241.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,2NF4I@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS2_k127_2030863_0	926550.CLDAP_34700	1.776e-104	351.0	COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	gly1	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HSJS2_k127_2030863_5	710696.Intca_1875	7.626e-24	111.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4FJ07@85021|Intrasporangiaceae	201174|Actinobacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
HSJS2_k127_2030863_6	1485545.JQLW01000005_gene1242	3.577e-16	88.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria	1224|Proteobacteria	O	Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
HSJS2_k127_2030863_1	1313172.YM304_32630	7.214e-101	334.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
HSJS2_k127_2030863_4	1157708.KB907457_gene2794	9.38e-41	166.0	COG1247@1|root,COG1247@2|Bacteria,1R6UW@1224|Proteobacteria,2W2QC@28216|Betaproteobacteria,4AHQC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_2069463_3	1333998.M2A_0722	1.755e-06	60.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HSJS2_k127_2069463_1	926550.CLDAP_35260	6.267e-145	481.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS2_k127_2069463_0	926569.ANT_02600	9.601e-150	495.0	COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS2_k127_2069463_2	311424.DhcVS_293	8.281e-115	380.0	COG3567@1|root,COG3567@2|Bacteria,2G7F0@200795|Chloroflexi,34DDN@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
HSJS2_k127_2073740_0	1040989.AWZU01000035_gene1775	3.599e-216	677.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2U10C@28211|Alphaproteobacteria,3JR02@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
HSJS2_k127_2073740_2	469383.Cwoe_2104	8.915e-40	164.0	COG1028@1|root,COG1028@2|Bacteria,2GNM4@201174|Actinobacteria,4CR6G@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_2073740_1	331869.BAL199_29295	2.798e-147	472.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TT4C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HSJS2_k127_2074244_0	1394178.AWOO02000002_gene1608	7.621e-125	431.0	COG1804@1|root,COG1804@2|Bacteria,2GMGE@201174|Actinobacteria,4EPCX@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2074244_2	502025.Hoch_4836	1.292e-94	325.0	COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria	1224|Proteobacteria	P	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_2074244_5	443255.SCLAV_5085	3.237e-12	78.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
HSJS2_k127_2074244_4	1429916.X566_10475	2.104e-63	220.0	COG2030@1|root,COG2030@2|Bacteria,1RD6F@1224|Proteobacteria,2UC91@28211|Alphaproteobacteria,3JZ3D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS2_k127_2074244_3	247633.GP2143_12134	2.991e-67	233.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
HSJS2_k127_2074244_1	42256.RradSPS_1165	2.823e-121	398.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
HSJS2_k127_2078813_1	867903.ThesuDRAFT_02064	1.779e-76	265.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCDT@538999|Clostridiales incertae sedis	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
HSJS2_k127_2078813_5	1210884.HG799468_gene13642	2.806e-28	117.0	COG2127@1|root,COG2127@2|Bacteria,2J06R@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the ClpS family	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
HSJS2_k127_2078813_3	1283283.ATXA01000016_gene59	6.835e-43	165.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HSJS2_k127_2078813_2	1469245.JFBG01000008_gene751	2.537e-45	177.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria,1SVTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HSJS2_k127_2078813_8	644966.Tmar_1742	3.042e-07	58.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_2078813_0	1123023.JIAI01000003_gene2850	1.402e-151	489.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2078813_4	1123023.JIAI01000003_gene2851	1.819e-29	126.0	COG1545@1|root,COG1545@2|Bacteria,2GS5U@201174|Actinobacteria	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_2078813_6	384765.SIAM614_17609	9.75e-12	75.0	COG1051@1|root,COG1051@2|Bacteria,1N3D8@1224|Proteobacteria,2U6GG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HSJS2_k127_2078813_7	1461580.CCAS010000001_gene44	8.682e-09	65.0	2AEM9@1|root,314H6@2|Bacteria,1VQ8R@1239|Firmicutes,4IIM3@91061|Bacilli,1ZPC1@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
HSJS2_k127_2083570_6	1133849.O3I_027875	5.313e-30	122.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FX0N@85025|Nocardiaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
HSJS2_k127_2083570_7	362242.MUL_2265	7.056e-11	69.0	COG0451@1|root,COG3848@1|root,COG0451@2|Bacteria,COG3848@2|Bacteria,2H2J1@201174|Actinobacteria,232PK@1762|Mycobacteriaceae	201174|Actinobacteria	GMT	PEP-utilising enzyme, mobile domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Epimerase,PEP-utilizers
HSJS2_k127_2083570_1	1121091.AUMP01000024_gene3029	1.171e-65	245.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HDHF@91061|Bacilli	91061|Bacilli	GT	Phosphotransferase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
HSJS2_k127_2083570_3	1133849.O3I_027875	2.344e-54	201.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FX0N@85025|Nocardiaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
HSJS2_k127_2083570_2	1048339.KB913029_gene4512	5.231e-56	214.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HSJS2_k127_2083570_0	285535.JOEY01000075_gene5963	2.21e-111	375.0	COG2141@1|root,COG2141@2|Bacteria,2GITK@201174|Actinobacteria	201174|Actinobacteria	C	Monooxygenase	limB	-	1.14.13.107	ko:K14733	ko00903,map00903	-	R06398,R09385,R09389,R09393	RC01506	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HSJS2_k127_2083570_4	235985.BBPN01000006_gene3693	3.874e-46	175.0	COG3393@1|root,COG3393@2|Bacteria,2GMQC@201174|Actinobacteria,2NEHN@228398|Streptacidiphilus	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
HSJS2_k127_2083570_5	247156.NFA_27860	4.818e-41	156.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria,4FVQI@85025|Nocardiaceae	201174|Actinobacteria	Q	amine oxidase	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
HSJS2_k127_2089259_3	1027371.GOALK_063_00050	2.557e-08	59.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4GCPK@85026|Gordoniaceae	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
HSJS2_k127_2089259_2	383372.Rcas_4391	2.697e-32	134.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi,375MV@32061|Chloroflexia	32061|Chloroflexia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HSJS2_k127_2089259_0	525904.Tter_1750	3.266e-261	819.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HSJS2_k127_2089259_1	269800.Tfu_1451	1.953e-32	140.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4EG3R@85012|Streptosporangiales	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
HSJS2_k127_2092525_4	883078.HMPREF9695_02692	4.354e-20	94.0	COG2128@1|root,COG2128@2|Bacteria,1QW8V@1224|Proteobacteria,2TWTB@28211|Alphaproteobacteria,3JZDW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2092525_0	1206732.BAGD01000054_gene1961	4.312e-107	360.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_2092525_1	1123023.JIAI01000019_gene2183	4.814e-99	330.0	COG1024@1|root,COG1024@2|Bacteria,2I9DY@201174|Actinobacteria	201174|Actinobacteria	I	enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS2_k127_2092525_3	1415780.JPOG01000001_gene64	3.393e-33	137.0	COG2258@1|root,COG2258@2|Bacteria,1RE2Q@1224|Proteobacteria,1SEFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2092525_2	316274.Haur_3402	4.554e-58	211.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
HSJS2_k127_2092525_5	1202768.JROF01000034_gene2215	1.414e-07	62.0	arCOG13343@1|root,arCOG13343@2157|Archaea,2XW0J@28890|Euryarchaeota,23TZ4@183963|Halobacteria	183963|Halobacteria	S	Halocarboxylic acid dehydrogenase DehI	-	-	-	-	-	-	-	-	-	-	-	-	DehI
HSJS2_k127_2099434_3	365046.Rta_06880	2.538e-79	274.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,2W01H@28216|Betaproteobacteria,4AGE3@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
HSJS2_k127_2099434_0	1146883.BLASA_3642	7.905e-142	473.0	COG1215@1|root,COG1215@2|Bacteria,2GKFI@201174|Actinobacteria,4ESRY@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	bcsA	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,PilZ
HSJS2_k127_2099434_4	1282876.BAOK01000001_gene2226	5.416e-24	109.0	2BYHJ@1|root,33QGK@2|Bacteria,1NTWN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2099434_2	247633.GP2143_17291	8.372e-93	319.0	COG1960@1|root,COG1960@2|Bacteria,1R6EH@1224|Proteobacteria,1RMXW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_2099434_1	264198.Reut_B3680	5.908e-99	334.0	COG4257@1|root,COG4257@2|Bacteria,1R448@1224|Proteobacteria,2W139@28216|Betaproteobacteria,1KEAH@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Carboxypeptidase regulatory-like domain	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg
HSJS2_k127_2102176_4	1121106.JQKB01000023_gene3571	2.118e-90	308.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSMN@28211|Alphaproteobacteria,2JVSH@204441|Rhodospirillales	204441|Rhodospirillales	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS2_k127_2102176_2	1313172.YM304_36000	4.894e-115	378.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
HSJS2_k127_2102176_3	682795.AciX8_3740	2.625e-92	326.0	COG2124@1|root,COG2124@2|Bacteria,3Y4Y2@57723|Acidobacteria,2JMFM@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_2102176_1	367299.JOEE01000004_gene1056	2.641e-156	498.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4FG5R@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HSJS2_k127_2102176_0	926550.CLDAP_06490	1.029e-162	528.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HSJS2_k127_2108044_0	525904.Tter_1789	3.94e-216	699.0	COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria	2|Bacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HSJS2_k127_2108044_1	555088.DealDRAFT_1545	1.304e-59	218.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,42JTN@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HSJS2_k127_212430_5	1449346.JQMO01000003_gene5928	5.043e-07	60.0	COG4948@1|root,COG4948@2|Bacteria,2HG8S@201174|Actinobacteria,2M4IG@2063|Kitasatospora	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
HSJS2_k127_212430_1	350054.Mflv_4597	1.148e-66	235.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria,233IA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Wyosine base formation	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
HSJS2_k127_212430_3	1211115.ALIQ01000076_gene3905	1.458e-30	126.0	COG3801@1|root,COG3801@2|Bacteria,1RGZ3@1224|Proteobacteria,2U95Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
HSJS2_k127_212430_2	1035308.AQYY01000002_gene514	8.429e-63	245.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,260AR@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HSJS2_k127_212430_4	106370.Francci3_3486	2.827e-30	135.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4EXBW@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_212430_0	1449049.JONW01000012_gene6	5.76e-72	247.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2U14P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS2_k127_2132241_2	479434.Sthe_1051	2.442e-62	218.0	COG0097@1|root,COG0097@2|Bacteria,2G6HZ@200795|Chloroflexi,27Y65@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
HSJS2_k127_2132241_5	2325.TKV_c20430	2.966e-43	162.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,42G9H@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
HSJS2_k127_2132241_7	161156.JQKW01000006_gene1046	2.394e-22	98.0	COG0199@1|root,COG0199@2|Bacteria,2GI3J@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
HSJS2_k127_2132241_0	309801.trd_0972	1.342e-69	240.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi,27XMS@189775|Thermomicrobia	189775|Thermomicrobia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
HSJS2_k127_2132241_6	381764.Fnod_1127	9.399e-27	121.0	COG0198@1|root,COG0198@2|Bacteria,2GD31@200918|Thermotogae	200918|Thermotogae	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
HSJS2_k127_2132241_4	479434.Sthe_1046	4.292e-50	188.0	COG0093@1|root,COG0093@2|Bacteria,2G6MZ@200795|Chloroflexi,27YG0@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
HSJS2_k127_2132241_8	555088.DealDRAFT_1514	7.573e-21	98.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42K48@68298|Syntrophomonadaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
HSJS2_k127_2132241_9	1449355.JQNR01000005_gene3712	1.147e-07	61.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
HSJS2_k127_2132241_3	644966.Tmar_2288	3.658e-52	187.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WCGY@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HSJS2_k127_2132241_1	1382306.JNIM01000001_gene3543	2.743e-64	226.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi	200795|Chloroflexi	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HSJS2_k127_2134813_0	393283.XP_007835630.1	2.265e-13	78.0	COG0666@1|root,KOG4177@2759|Eukaryota,39PZA@33154|Opisthokonta,3P1UY@4751|Fungi,3QU8R@4890|Ascomycota	4751|Fungi	M	Heterokaryon incompatibility protein (HET)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,HET
HSJS2_k127_2135090_2	925775.XVE_2604	9.535e-55	201.0	COG2755@1|root,COG2755@2|Bacteria,1P3T8@1224|Proteobacteria,1T09G@1236|Gammaproteobacteria,1XCZI@135614|Xanthomonadales	135614|Xanthomonadales	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HSJS2_k127_2135090_1	551789.ATVJ01000001_gene2146	1.365e-109	368.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha beta hydrolase	-	-	2.7.10.2,3.3.2.9	ko:K01253,ko:K08253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HSJS2_k127_2135090_0	338963.Pcar_2038	1.265e-127	425.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,43S8W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HSJS2_k127_2135090_3	479434.Sthe_0401	9.543e-46	174.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi,27Y4G@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
HSJS2_k127_214923_4	8479.XP_008171586.1	0.0006429	45.0	COG2030@1|root,KOG1206@2759|Eukaryota,3A1K8@33154|Opisthokonta,3BQUF@33208|Metazoa,3D5NN@33213|Bilateria,488TZ@7711|Chordata,499EP@7742|Vertebrata,4CM54@8459|Testudines	33208|Metazoa	I	Hydroxyacyl-thioester dehydratase type 2	HTD2	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0018812,GO:0019438,GO:0019637,GO:0019693,GO:0031974,GO:0031981,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035337,GO:0035383,GO:0035384,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0046949,GO:0051186,GO:0051188,GO:0055086,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576	3.1.26.5,4.2.1.55	ko:K14529,ko:K17865	ko00630,ko00650,ko01120,ko01200,ko03013,map00630,map00650,map01120,map01200,map03013	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	MaoC_dehydratas
HSJS2_k127_214923_3	106370.Francci3_1659	3.328e-19	98.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4ESM6@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
HSJS2_k127_214923_1	526227.Mesil_1007	1.431e-87	298.0	COG0396@1|root,COG0396@2|Bacteria,1WIF0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HSJS2_k127_214923_0	1283299.AUKG01000002_gene3709	2.129e-215	693.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
HSJS2_k127_214923_2	479434.Sthe_1524	8.623e-46	182.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HSJS2_k127_2159556_3	525904.Tter_1356	1.209e-77	272.0	COG1193@1|root,COG1193@2|Bacteria,2NNS1@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HSJS2_k127_2159556_1	404589.Anae109_4157	6.192e-134	443.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
HSJS2_k127_2159556_2	243164.DET0600	1.727e-115	383.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi,34CWR@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS2_k127_2159556_0	552811.Dehly_0744	5.016e-135	449.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi,34CNE@301297|Dehalococcoidia	301297|Dehalococcoidia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS2_k127_2160612_3	68260.JOAY01000033_gene2472	2.278e-05	48.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_2160612_1	671143.DAMO_1992	2.186e-106	351.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
HSJS2_k127_2160612_0	298655.KI912266_gene6519	3.332e-269	841.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HSJS2_k127_2160612_2	298655.KI912266_gene6518	5.162e-23	101.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria,4ES2J@85013|Frankiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2160671_0	552811.Dehly_1367	2.828e-244	784.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi,34CVN@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HSJS2_k127_2160671_5	1009370.ALO_09484	1.141e-32	136.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H30V@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
HSJS2_k127_2160671_4	1382356.JQMP01000003_gene2109	6.575e-72	260.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi,27Y0S@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
HSJS2_k127_2160671_3	1382306.JNIM01000001_gene2574	5.786e-72	259.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi	200795|Chloroflexi	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HSJS2_k127_2160671_2	1128421.JAGA01000003_gene3142	6.068e-103	348.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
HSJS2_k127_2160671_1	326424.FRAAL6579	6.484e-227	719.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4ES4C@85013|Frankiales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
HSJS2_k127_2161918_1	596153.Alide_1191	6.724e-23	103.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2VQ52@28216|Betaproteobacteria,4ADVB@80864|Comamonadaceae	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF488,UDG
HSJS2_k127_2161918_2	1265845.PWEIH_16918	7.948e-11	67.0	COG3708@1|root,COG3708@2|Bacteria,1VJT1@1239|Firmicutes,4HREN@91061|Bacilli	91061|Bacilli	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
HSJS2_k127_2161918_0	1283283.ATXA01000001_gene561	1.377e-52	195.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4EVPG@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS2_k127_2164892_0	326427.Cagg_2331	1.793e-151	501.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,37520@32061|Chloroflexia	32061|Chloroflexia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HSJS2_k127_2164892_2	552811.Dehly_1128	1.297e-45	183.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi,34CMT@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HSJS2_k127_2164892_3	512565.AMIS_6680	5.759e-29	123.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4DDER@85008|Micromonosporales	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HSJS2_k127_2164892_4	243164.DET0395	2.356e-20	100.0	COG0637@1|root,COG1214@1|root,COG0637@2|Bacteria,COG1214@2|Bacteria,2G6ZZ@200795|Chloroflexi,34D2B@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Glycoprotease family	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Peptidase_M22
HSJS2_k127_2164892_1	1121422.AUMW01000011_gene119	1.959e-49	185.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,24JM5@186801|Clostridia,261SD@186807|Peptococcaceae	186801|Clostridia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HSJS2_k127_2167163_1	285514.JNWO01000001_gene4293	8.357e-99	347.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2167163_4	290512.Paes_0062	2.205e-57	208.0	COG3440@1|root,COG3440@2|Bacteria	2|Bacteria	V	regulation of methylation-dependent chromatin silencing	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
HSJS2_k127_2167163_2	675635.Psed_4123	1.35e-88	308.0	COG0778@1|root,COG0778@2|Bacteria,2I6AB@201174|Actinobacteria,4E92W@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HSJS2_k127_2167163_5	1131813.AQVT01000001_gene1378	1.36e-44	169.0	2DMXW@1|root,32UAS@2|Bacteria,1PP5A@1224|Proteobacteria,2V1NG@28211|Alphaproteobacteria,1JXC5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2167163_8	748247.AZKH_4269	2.114e-34	140.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KV0G@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HSJS2_k127_2167163_6	326424.FRAAL1590	1.107e-43	164.0	COG2764@1|root,COG2764@2|Bacteria,2GMZD@201174|Actinobacteria,4EVHP@85013|Frankiales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
HSJS2_k127_2167163_3	83332.Rv1190	1.897e-63	228.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,23610@1762|Mycobacteriaceae	201174|Actinobacteria	S	Haloalkane dehalogenase	dhmA2	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS2_k127_2167163_0	402881.Plav_2009	9.103e-144	466.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria,1JPBG@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	MA20_16305	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
HSJS2_k127_2167163_7	1122611.KB903950_gene6424	7.222e-38	148.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria,4EK85@85012|Streptosporangiales	201174|Actinobacteria	EGP	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_2167163_9	1293048.CBMB010000004_gene2567	1.235e-05	55.0	COG2050@1|root,arCOG00777@2157|Archaea,2XXD0@28890|Euryarchaeota,23VME@183963|Halobacteria	183963|Halobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HSJS2_k127_2177166_0	159450.NH14_20430	1.125e-98	334.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2VZAM@28216|Betaproteobacteria,1K5X3@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Flavin-binding monooxygenase-like	-	-	1.14.13.84	ko:K14520	ko00363,ko01100,ko01120,map00363,map01100,map01120	-	R06892	RC01644	ko00000,ko00001,ko01000	-	-	-	FMO-like
HSJS2_k127_2177166_4	471223.GWCH70_0587	3.666e-05	56.0	2E30A@1|root,32Y0V@2|Bacteria,1VBWT@1239|Firmicutes,4HMCW@91061|Bacilli,1WF7D@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2177166_3	438753.AZC_1569	3.965e-33	139.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,3EYZ3@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	Response regulator receiver	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_2177166_1	882378.RBRH_02495	7.658e-46	177.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_2177166_2	408672.NBCG_05188	3.184e-43	169.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DNTM@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_2188940_0	479434.Sthe_2126	9.587e-118	389.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,27YUB@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS2_k127_2188940_1	479434.Sthe_2125	1.148e-72	261.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27YYN@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS2_k127_2191484_1	479434.Sthe_0156	7.804e-66	243.0	COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
HSJS2_k127_2191484_2	309801.trd_1551	8.921e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi,27XKP@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_2191484_0	42256.RradSPS_0358	2.017e-184	609.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
HSJS2_k127_2207328_0	1158606.I579_00783	1.86e-56	208.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,4AZ64@81852|Enterococcaceae	91061|Bacilli	D	Cellulose biosynthesis protein BcsQ	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HSJS2_k127_2207328_2	248742.XP_005647707.1	4.377e-36	149.0	2ECHE@1|root,2SICA@2759|Eukaryota,37ZF4@33090|Viridiplantae,34JHP@3041|Chlorophyta	3041|Chlorophyta	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
HSJS2_k127_2207328_4	479434.Sthe_0167	8.273e-25	117.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi,27XWI@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative single-stranded nucleic acids-binding domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,R3H
HSJS2_k127_2207328_1	311424.DhcVS_910	1.167e-45	177.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi,34D1I@301297|Dehalococcoidia	301297|Dehalococcoidia	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HSJS2_k127_2207328_6	547559.Nmag_0609	4.474e-13	82.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria	183963|Halobacteria	C	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
HSJS2_k127_2207328_5	526225.Gobs_3060	1.622e-19	98.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4ETJI@85013|Frankiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HSJS2_k127_2207328_8	867845.KI911784_gene2749	1.069e-07	61.0	COG0230@1|root,COG0230@2|Bacteria,2G7BX@200795|Chloroflexi,3760E@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HSJS2_k127_2207328_3	357808.RoseRS_2641	3.874e-35	155.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,374VP@32061|Chloroflexia	32061|Chloroflexia	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
HSJS2_k127_2207328_9	933801.Ahos_0200	0.0001209	45.0	COG1225@1|root,arCOG00310@2157|Archaea,2XQPI@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS2_k127_2207328_7	1206733.BAGC01000026_gene4814	2.034e-12	71.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4G0FN@85025|Nocardiaceae	201174|Actinobacteria	O	Redoxin	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS2_k127_2214123_0	518766.Rmar_1739	3.096e-71	246.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HSJS2_k127_2214123_1	1242864.D187_007980	6.421e-60	225.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,438PG@68525|delta/epsilon subdivisions,2X3X6@28221|Deltaproteobacteria,2YXF3@29|Myxococcales	28221|Deltaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_221640_1	485913.Krac_0161	9.453e-11	63.0	COG3316@1|root,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
HSJS2_k127_221640_2	682795.AciX8_1778	1.1e-08	66.0	COG0392@1|root,COG0392@2|Bacteria,3Y4Q3@57723|Acidobacteria,2JJ7R@204432|Acidobacteriia	204432|Acidobacteriia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HSJS2_k127_221640_0	1056816.JAFQ01000004_gene1633	6.814e-16	85.0	COG1547@1|root,COG1547@2|Bacteria,2IHUS@201174|Actinobacteria,4G0ZQ@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
HSJS2_k127_221640_3	298653.Franean1_6717	7.574e-05	48.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve_3
HSJS2_k127_2220794_1	693661.Arcve_0284	7.747e-51	196.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVR7@28890|Euryarchaeota,245V0@183980|Archaeoglobi	183980|Archaeoglobi	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_2220794_0	243164.DET0364	2.303e-70	254.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi,34D77@301297|Dehalococcoidia	301297|Dehalococcoidia	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HSJS2_k127_2231579_4	867903.ThesuDRAFT_02320	7.053e-18	95.0	COG3634@1|root,COG3634@2|Bacteria,1V40Z@1239|Firmicutes,24JKA@186801|Clostridia	186801|Clostridia	O	TIGRFAM Glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
HSJS2_k127_2231579_2	552811.Dehly_0528	1.412e-36	154.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi,34D5W@301297|Dehalococcoidia	301297|Dehalococcoidia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HSJS2_k127_2231579_0	552811.Dehly_0527	5.348e-95	329.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,34CIQ@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HSJS2_k127_2231579_1	1382306.JNIM01000001_gene4122	2.137e-41	165.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
HSJS2_k127_2231579_3	1382306.JNIM01000001_gene4124	2.418e-34	140.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HSJS2_k127_2242540_5	1304876.AZVC01000016_gene280	7.146e-06	49.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,1W859@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA8	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_2242540_2	1077974.GOEFS_044_00250	3.904e-75	263.0	COG2141@1|root,COG2141@2|Bacteria,2H62W@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_2242540_1	1128421.JAGA01000004_gene2704	3.119e-95	328.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_2242540_0	1033743.CAES01000098_gene2690	1.149e-103	353.0	COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,26V2H@186822|Paenibacillaceae	91061|Bacilli	Q	cytochrome P450	bioI	GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.14.14.46	ko:K16593	ko00780,ko01100,map00780,map01100	M00573	R10123	-	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
HSJS2_k127_2242540_3	68223.JNZY01000002_gene4926	2.998e-12	73.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
HSJS2_k127_2242540_4	5762.XP_002676727.1	2.436e-09	59.0	COG0339@1|root,KOG2089@2759|Eukaryota	2759|Eukaryota	E	metalloendopeptidase activity	THOP1	GO:0000209,GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005759,GO:0005773,GO:0005794,GO:0005829,GO:0005886,GO:0006109,GO:0006111,GO:0006464,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010467,GO:0010675,GO:0010830,GO:0010906,GO:0012505,GO:0016020,GO:0016202,GO:0016485,GO:0016567,GO:0016787,GO:0019222,GO:0019538,GO:0023052,GO:0031323,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031976,GO:0031984,GO:0032446,GO:0033218,GO:0034641,GO:0035556,GO:0036211,GO:0042221,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0046686,GO:0048046,GO:0048634,GO:0048641,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051147,GO:0051153,GO:0051239,GO:0051604,GO:0051716,GO:0062012,GO:0065007,GO:0070011,GO:0070012,GO:0070013,GO:0070647,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1901861,GO:1902809,GO:2000026,GO:2001014	3.4.15.5,3.4.24.15,3.4.24.16,3.4.24.37,3.4.24.70	ko:K01284,ko:K01392,ko:K01393,ko:K01405,ko:K01414,ko:K05752,ko:K08202,ko:K13726	ko04614,ko04810,ko05143,ko05231,map04614,map04810,map05143,map05231	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	2.A.1.19.2,2.A.1.19.3	-	-	Peptidase_M3
HSJS2_k127_2248742_0	463191.SSEG_05795	5.601e-67	240.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
HSJS2_k127_2248742_1	222534.KB893725_gene298	1.486e-24	119.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4ESAF@85013|Frankiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
HSJS2_k127_2248742_2	479434.Sthe_2114	4.035e-10	64.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi,27YHT@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2248817_2	1128421.JAGA01000002_gene723	4.625e-69	240.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HSJS2_k127_2248817_4	1382304.JNIL01000001_gene1939	5.119e-55	201.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,2782H@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HSJS2_k127_2248817_5	383372.Rcas_4001	3.442e-50	181.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi,375IQ@32061|Chloroflexia	32061|Chloroflexia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HSJS2_k127_2248817_6	1120972.AUMH01000017_gene741	4.291e-46	169.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,278EH@186823|Alicyclobacillaceae	91061|Bacilli	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HSJS2_k127_2248817_8	742742.HMPREF9452_01443	9.172e-12	66.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4CWQV@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HSJS2_k127_2248817_7	357808.RoseRS_1163	7.826e-29	117.0	COG0361@1|root,COG0361@2|Bacteria,2G70W@200795|Chloroflexi,375UY@32061|Chloroflexia	32061|Chloroflexia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HSJS2_k127_2248817_1	1120973.AQXL01000112_gene1094	2.612e-75	264.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HSJS2_k127_2248817_3	693661.Arcve_1092	2.636e-66	239.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
HSJS2_k127_2248817_0	552811.Dehly_1077	1.827e-148	482.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,34CNS@301297|Dehalococcoidia	301297|Dehalococcoidia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HSJS2_k127_2257551_3	1255043.TVNIR_1705	1.964e-21	99.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HSJS2_k127_2257551_2	749222.Nitsa_1829	1.14e-25	113.0	COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,42SBR@68525|delta/epsilon subdivisions,2YPGJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM DsrE family protein	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
HSJS2_k127_2257551_4	443143.GM18_1826	4.982e-21	96.0	COG0640@1|root,COG0640@2|Bacteria,1RGYC@1224|Proteobacteria,42X86@68525|delta/epsilon subdivisions,2WSJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HSJS2_k127_2257551_0	1123288.SOV_3c01310	2.825e-33	138.0	COG1571@1|root,COG1571@2|Bacteria,1V2YE@1239|Firmicutes	1239|Firmicutes	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2257551_1	266117.Rxyl_1027	2.4e-28	120.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4CQ0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
HSJS2_k127_2268211_3	1382306.JNIM01000001_gene2377	3.024e-73	257.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi	200795|Chloroflexi	EQ	Hydantoinaseoxoprolinase domain protein	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
HSJS2_k127_2268211_2	926550.CLDAP_11550	5.269e-174	562.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
HSJS2_k127_2268211_4	221288.JH992901_gene612	1.198e-42	173.0	COG2234@1|root,COG2234@2|Bacteria,1G4A2@1117|Cyanobacteria,1JI76@1189|Stigonemataceae	1117|Cyanobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HSJS2_k127_2268211_5	483219.LILAB_09475	5.449e-11	75.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
HSJS2_k127_2268211_1	797209.ZOD2009_19363	2.603e-191	611.0	COG4799@1|root,arCOG02705@2157|Archaea,2XSVM@28890|Euryarchaeota,23T6H@183963|Halobacteria	183963|Halobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB2	GO:0003674,GO:0003824,GO:0004658,GO:0016421,GO:0016874,GO:0016885	2.1.3.15,6.4.1.2,6.4.1.3	ko:K19312	ko00280,ko00630,ko00640,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01120,map01130,map01200	M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HSJS2_k127_2268211_0	1177928.TH2_10099	1.967e-209	657.0	COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria,2JQ2K@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HSJS2_k127_2270024_2	1172186.KB911462_gene681	2.451e-12	70.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,232VJ@1762|Mycobacteriaceae	201174|Actinobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HSJS2_k127_2270024_1	397278.JOJN01000001_gene2790	1.297e-17	94.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,4DN0W@85009|Propionibacteriales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
HSJS2_k127_2270024_0	1157708.KB907454_gene3109	2.859e-40	162.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria	1224|Proteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	ybfF	-	-	ko:K01175,ko:K06049	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS2_k127_2283938_2	479434.Sthe_0414	4.33e-19	99.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,27XKY@189775|Thermomicrobia	189775|Thermomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
HSJS2_k127_2283938_0	243164.DET0551	2.858e-138	456.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,34D2Y@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS2_k127_2283938_1	552811.Dehly_1579	1.744e-35	145.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi,34CJ2@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
HSJS2_k127_229058_0	383372.Rcas_3710	2.369e-89	298.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,37547@32061|Chloroflexia	32061|Chloroflexia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HSJS2_k127_229058_1	292459.STH2132	2.887e-38	159.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia	186801|Clostridia	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
HSJS2_k127_229099_6	1397696.KK211189_gene2556	9.758e-09	59.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_229099_5	485913.Krac_2143	1.62e-13	75.0	COG5485@1|root,COG5485@2|Bacteria,2G7DA@200795|Chloroflexi	200795|Chloroflexi	P	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
HSJS2_k127_229099_7	1123284.KB899043_gene413	0.0001207	47.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_229099_3	1121406.JAEX01000021_gene1458	4.641e-26	111.0	COG1917@1|root,COG1917@2|Bacteria,1N13F@1224|Proteobacteria,43BFG@68525|delta/epsilon subdivisions,2X6TV@28221|Deltaproteobacteria,2MH6T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS2_k127_229099_0	1380390.JIAT01000009_gene522	2.655e-267	835.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
HSJS2_k127_229099_4	926569.ANT_10990	6.785e-16	83.0	COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi	200795|Chloroflexi	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HSJS2_k127_229099_2	1121445.ATUZ01000020_gene2118	2.024e-66	245.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42PEC@68525|delta/epsilon subdivisions,2X5JG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HSJS2_k127_229099_1	1121472.AQWN01000007_gene1130	3.736e-77	263.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,249UD@186801|Clostridia,25ZZC@186807|Peptococcaceae	186801|Clostridia	C	PFAM Transketolase	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
HSJS2_k127_2298095_3	1206730.BAGA01000070_gene1683	2.748e-27	116.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,4FW2K@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_2298095_0	1429916.X566_19625	1.439e-80	295.0	COG0300@1|root,COG0300@2|Bacteria,1R25N@1224|Proteobacteria,2TZB2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_2298095_2	479434.Sthe_2989	7.496e-40	167.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_2298095_1	485913.Krac_4715	7.555e-69	246.0	COG2272@1|root,COG2272@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
HSJS2_k127_2302773_2	1123322.KB904687_gene4987	1.824e-36	145.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
HSJS2_k127_2302773_1	512565.AMIS_45030	1.65e-80	277.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS2_k127_2302773_0	1306174.JODP01000012_gene6242	2.335e-116	389.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HSJS2_k127_2302773_3	311424.DhcVS_640	4.78e-09	62.0	COG2331@1|root,COG2331@2|Bacteria,2GATM@200795|Chloroflexi,34DB9@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
HSJS2_k127_2312491_1	585531.HMPREF0063_12549	2.844e-64	232.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,4DN26@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	fadE29	GO:0000166,GO:0003674,GO:0005488,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016125,GO:0016127,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0046164,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0051704,GO:0055114,GO:0071704,GO:0071949,GO:0072329,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_2312491_2	479434.Sthe_3003	1.022e-57	217.0	COG1804@1|root,COG1804@2|Bacteria,2GABR@200795|Chloroflexi,27XHH@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_2312491_3	272558.10173085	2.946e-41	168.0	COG0477@1|root,COG2814@2|Bacteria,1TQF3@1239|Firmicutes,4HDR6@91061|Bacilli,1ZANN@1386|Bacillus	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_2312491_0	511062.GU3_05375	1.018e-67	239.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1Y59G@135624|Aeromonadales	135624|Aeromonadales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
HSJS2_k127_2312491_4	3067.XP_002958724.1	3.303e-37	152.0	COG0225@1|root,COG0545@1|root,KOG0544@2759|Eukaryota,KOG1635@2759|Eukaryota,37JIQ@33090|Viridiplantae,34ID2@3041|Chlorophyta	3041|Chlorophyta	O	Peptide methionine sulfoxide reductase	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C,PMSR
HSJS2_k127_2312491_5	264198.Reut_B4912	0.000786	45.0	2EMYS@1|root,30IIY@2|Bacteria,1PXCT@1224|Proteobacteria,2WCU0@28216|Betaproteobacteria,1KBD6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
HSJS2_k127_2333352_0	935863.AWZR01000014_gene2987	2.884e-59	222.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,PilZ
HSJS2_k127_2333352_1	381666.H16_A0147	1.256e-21	104.0	COG2021@1|root,COG2021@2|Bacteria,1QU84@1224|Proteobacteria,2VRYJ@28216|Betaproteobacteria,1K0JE@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM alpha beta hydrolase fold	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
HSJS2_k127_2333352_2	1463881.KL591025_gene4204	7.697e-15	85.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_4,Trans_reg_C
HSJS2_k127_233998_0	460265.Mnod_3429	2.962e-222	701.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,1JRH7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3
HSJS2_k127_233998_1	264198.Reut_C6079	7.11e-148	482.0	COG2015@1|root,COG2015@2|Bacteria,1R9IE@1224|Proteobacteria,2VKAR@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Alkyl sulfatase and related hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
HSJS2_k127_233998_3	479434.Sthe_2506	4.28e-55	214.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_233998_4	582515.KR51_00022190	1.711e-24	115.0	COG0420@1|root,COG0420@2|Bacteria,1FZXM@1117|Cyanobacteria	1117|Cyanobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
HSJS2_k127_233998_5	452471.Aasi_0859	3.938e-15	85.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,47JXP@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HSJS2_k127_233998_2	479431.Namu_4273	1.124e-66	239.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_2344233_3	1397528.Q671_01515	5.898e-07	53.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	hadL	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
HSJS2_k127_2344233_2	110663.KI911558_gene108	2.388e-10	71.0	COG0857@1|root,COG0857@2|Bacteria,1G0QB@1117|Cyanobacteria,1GZVA@1129|Synechococcus	1117|Cyanobacteria	C	BioD-like N-terminal domain of phosphotransacetylase	pta	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
HSJS2_k127_2344233_1	479434.Sthe_0724	2.345e-77	274.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
HSJS2_k127_2344233_0	255470.cbdbA1111	6.959e-134	443.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HSJS2_k127_2346952_2	1121468.AUBR01000005_gene35	0.0001654	53.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,42H0N@68295|Thermoanaerobacterales	186801|Clostridia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
HSJS2_k127_2346952_3	1385515.N791_01885	0.0003077	53.0	COG1716@1|root,COG1716@2|Bacteria,1PCDM@1224|Proteobacteria,1SXCY@1236|Gammaproteobacteria,1X63E@135614|Xanthomonadales	135614|Xanthomonadales	T	FHA domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
HSJS2_k127_2346952_1	644966.Tmar_1212	2.227e-07	61.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
HSJS2_k127_2346952_0	635013.TherJR_2811	1.255e-21	106.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,262WB@186807|Peptococcaceae	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
HSJS2_k127_2349763_4	1454010.JEOE01000004_gene42	1.98e-36	145.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
HSJS2_k127_2349763_0	59538.XP_005968778.1	8.263e-129	423.0	COG1062@1|root,KOG0022@2759|Eukaryota,397PJ@33154|Opisthokonta,3BIQH@33208|Metazoa,3CYWE@33213|Bilateria,4871P@7711|Chordata,491PB@7742|Vertebrata,3J1Y5@40674|Mammalia	2759|Eukaryota	Q	alcohol dehydrogenase (NAD) activity	ADH1	GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121,ko:K02267,ko:K13980,ko:K18857	ko00010,ko00071,ko00190,ko00350,ko00592,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,ko05204,map00010,map00071,map00190,map00350,map00592,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map04260,map04714,map04932,map05010,map05012,map05016,map05204	M00154	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310,R10783	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	3.D.4.11,3.D.4.8	-	-	ADH_N,ADH_zinc_N
HSJS2_k127_2349763_7	643648.Slip_1922	6.68e-09	68.0	COG4961@1|root,COG4961@2|Bacteria,1UJS8@1239|Firmicutes,25F8K@186801|Clostridia	186801|Clostridia	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
HSJS2_k127_2349763_6	479434.Sthe_1080	7.463e-23	113.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_4
HSJS2_k127_2349763_1	479434.Sthe_1081	1.08e-88	310.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS2_k127_2349763_5	512565.AMIS_7420	4.663e-24	117.0	COG1277@1|root,COG1277@2|Bacteria,2GKKP@201174|Actinobacteria,4D8U0@85008|Micromonosporales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HSJS2_k127_2349763_2	211114.JOEF01000019_gene646	5.586e-88	302.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4E8PM@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS2_k127_2349763_3	867845.KI911784_gene433	4.237e-53	201.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HSJS2_k127_2361463_4	546414.Deide_20960	1.873e-08	58.0	COG4872@1|root,COG4872@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157,GDYXXLXY
HSJS2_k127_2361463_1	1333998.M2A_2531	2.34e-13	77.0	COG4929@1|root,COG4929@2|Bacteria,1NURJ@1224|Proteobacteria,2TV9N@28211|Alphaproteobacteria,4BSWW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
HSJS2_k127_2361463_5	35754.JNYJ01000021_gene421	1.574e-05	53.0	291S1@1|root,2ZPBY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2361463_3	67332.FM21_23265	2.8e-09	63.0	COG3871@1|root,COG3871@2|Bacteria,2I31R@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_2361463_2	314230.DSM3645_11122	2.669e-13	75.0	COG1917@1|root,COG1917@2|Bacteria,2J1N5@203682|Planctomycetes	203682|Planctomycetes	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2361463_0	1231391.AMZF01000052_gene1170	8.149e-25	108.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2VWVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_2370206_2	1382356.JQMP01000003_gene1530	3.161e-28	119.0	COG0624@1|root,COG0624@2|Bacteria,2GB9S@200795|Chloroflexi,27YDU@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HSJS2_k127_2370206_3	1415755.JQLV01000001_gene1689	1.385e-24	115.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1XMBN@135619|Oceanospirillales	135619|Oceanospirillales	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HSJS2_k127_2370206_6	1286106.MPL1_08422	7.508e-20	99.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS,PAS_3,PAS_4,PAS_9
HSJS2_k127_2370206_1	8496.XP_006274203.1	1.018e-31	139.0	COG0491@1|root,KOG0813@2759|Eukaryota,38BZ4@33154|Opisthokonta,3BES6@33208|Metazoa,3CSY3@33213|Bilateria,4893A@7711|Chordata,494N7@7742|Vertebrata	33208|Metazoa	S	endoribonuclease activity	LACTB2	GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_2370206_8	118161.KB235922_gene5337	4.158e-11	72.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1GC8T@1117|Cyanobacteria	1117|Cyanobacteria	Q	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase
HSJS2_k127_2370206_0	266779.Meso_0803	7.492e-34	145.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2U67Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
HSJS2_k127_2370206_4	1219045.BV98_002630	6.653e-24	108.0	COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria,2U2R8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_N
HSJS2_k127_2370206_7	979556.MTES_1380	8.665e-16	87.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria,4FQF6@85023|Microbacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,MarR_2
HSJS2_k127_2370206_5	641524.ADICYQ_1920	2.101e-21	98.0	COG2267@1|root,COG2267@2|Bacteria,4NK80@976|Bacteroidetes,47NWA@768503|Cytophagia	976|Bacteroidetes	I	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_2375641_0	871968.DESME_08930	2.515e-08	67.0	2E2CM@1|root,32XHK@2|Bacteria,1VCFP@1239|Firmicutes,24Q3M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2380547_4	1306406.ASHX01000002_gene4663	6.251e-15	86.0	COG1672@1|root,COG1672@2|Bacteria,2IGAA@201174|Actinobacteria	201174|Actinobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
HSJS2_k127_2380547_5	29540.C481_04386	1.908e-13	75.0	COG3478@1|root,arCOG05073@2157|Archaea,2Y03G@28890|Euryarchaeota,23XMS@183963|Halobacteria	183963|Halobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon domain	-	-	-	ko:K07069	-	-	-	-	ko00000	-	-	-	zinc_ribbon_13
HSJS2_k127_2380547_6	47763.JNZA01000012_gene6470	7.268e-12	72.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
HSJS2_k127_2380547_2	1382306.JNIM01000001_gene3677	9.999e-53	199.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
HSJS2_k127_2380547_1	714961.BFZC1_01212	2.004e-81	279.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,3IX9R@400634|Lysinibacillus	91061|Bacilli	IQ	Short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_2380547_3	1120949.KB903336_gene9641	3.183e-22	105.0	2BWWR@1|root,2ZG0F@2|Bacteria,2IJ2X@201174|Actinobacteria,4DDGM@85008|Micromonosporales	201174|Actinobacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_2382423_0	1210884.HG799466_gene12809	1.706e-160	518.0	COG2308@1|root,COG2308@2|Bacteria,2IXE6@203682|Planctomycetes	203682|Planctomycetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
HSJS2_k127_2382423_1	1123261.AXDW01000017_gene3143	1.013e-17	87.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1X4EN@135614|Xanthomonadales	135614|Xanthomonadales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HSJS2_k127_2386009_1	1150469.RSPPHO_00932	5.03e-20	106.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria,2JUSX@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HSJS2_k127_2386009_0	1128421.JAGA01000003_gene3678	4.496e-107	381.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
HSJS2_k127_2386009_2	555088.DealDRAFT_1223	1.145e-13	85.0	COG2909@1|root,COG2909@2|Bacteria,1VKHN@1239|Firmicutes	1239|Firmicutes	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
HSJS2_k127_2386009_3	1218075.BAYA01000031_gene5999	0.0002986	49.0	COG5485@1|root,COG5485@2|Bacteria,1NG9D@1224|Proteobacteria,2WG67@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
HSJS2_k127_2396072_0	234267.Acid_5780	5.478e-87	324.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
HSJS2_k127_2396072_1	525368.HMPREF0591_5036	6.811e-35	156.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,234SY@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HSJS2_k127_2396072_3	1121861.KB899910_gene724	5.494e-05	51.0	COG5349@1|root,COG5349@2|Bacteria,1N0WU@1224|Proteobacteria,2UCE7@28211|Alphaproteobacteria,2JTDR@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
HSJS2_k127_2396072_2	113395.AXAI01000012_gene6974	4.844e-16	79.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2UFVV@28211|Alphaproteobacteria,3JYW1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS2_k127_2398276_7	1305735.JAFT01000005_gene3572	7.661e-28	115.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,2PDVK@252301|Oceanicola	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	MA20_32335	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HSJS2_k127_2398276_3	515635.Dtur_1137	3.275e-52	200.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
HSJS2_k127_2398276_2	525904.Tter_1430	1.661e-63	237.0	COG0544@1|root,COG0544@2|Bacteria,2NPBN@2323|unclassified Bacteria	2|Bacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
HSJS2_k127_2398276_1	255470.cbdbA666	8.246e-84	284.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi,34D07@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HSJS2_k127_2398276_0	485913.Krac_0006	8.387e-175	561.0	COG1219@1|root,COG1219@2|Bacteria,2G661@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HSJS2_k127_2398276_4	926550.CLDAP_14750	4.638e-46	179.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HSJS2_k127_2398276_6	926569.ANT_04780	2.046e-35	145.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HSJS2_k127_2398276_5	204669.Acid345_1383	2.564e-39	152.0	2CEY7@1|root,2Z8CG@2|Bacteria,3Y70V@57723|Acidobacteria,2JKPR@204432|Acidobacteriia	204432|Acidobacteriia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2402537_2	1449355.JQNR01000003_gene356	4.255e-74	264.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_2402537_1	1382306.JNIM01000001_gene623	3.105e-97	331.0	COG2124@1|root,COG2124@2|Bacteria,2G7SX@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_2402537_0	390989.JOEG01000041_gene2934	7.866e-109	388.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4DBG8@85008|Micromonosporales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
HSJS2_k127_2402537_3	380358.XALC_0615	1.051e-33	134.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1X72T@135614|Xanthomonadales	135614|Xanthomonadales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HSJS2_k127_2402537_4	215803.DB30_8135	3.309e-29	125.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42UEE@68525|delta/epsilon subdivisions,2WQHS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HSJS2_k127_2402537_5	365046.Rta_07180	1.859e-19	97.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,4A9S9@80864|Comamonadaceae	28216|Betaproteobacteria	G	phosphoglycerate mutase	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HSJS2_k127_2402537_6	387092.NIS_1261	0.0001147	45.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HSJS2_k127_2410788_0	404589.Anae109_3011	4.245e-182	596.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
HSJS2_k127_2416464_0	290397.Adeh_2438	1.919e-116	389.0	COG1032@1|root,COG1032@2|Bacteria,1Q3ZA@1224|Proteobacteria,439T3@68525|delta/epsilon subdivisions,2X567@28221|Deltaproteobacteria,2Z064@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HSJS2_k127_2418357_2	298654.FraEuI1c_2849	1.504e-27	125.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	ysnB	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HSJS2_k127_2418357_0	243164.DET0380	5.627e-126	410.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi,34D6P@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
HSJS2_k127_2418357_1	656024.FsymDg_2554	5.981e-63	226.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4ESCW@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
HSJS2_k127_2418357_3	1128421.JAGA01000002_gene685	6.026e-05	50.0	COG3854@1|root,COG3854@2|Bacteria,2NQEN@2323|unclassified Bacteria	2|Bacteria	S	R3H domain	ycf45	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
HSJS2_k127_2425448_3	1120972.AUMH01000010_gene329	1.33e-57	213.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,278I2@186823|Alicyclobacillaceae	91061|Bacilli	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HSJS2_k127_2425448_4	548477.HMPREF0294_2148	1.876e-43	168.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,22JQT@1653|Corynebacteriaceae	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HSJS2_k127_2425448_5	1382356.JQMP01000003_gene2415	3.035e-37	150.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi,27Y83@189775|Thermomicrobia	189775|Thermomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HSJS2_k127_2425448_1	448385.sce7407	4.757e-176	572.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2YU49@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
HSJS2_k127_2425448_0	880073.Calab_2574	0.0	1125.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HSJS2_k127_2425448_2	243164.DET0553	4.332e-106	361.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi,34CSV@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
HSJS2_k127_2425448_6	926550.CLDAP_37420	0.0004725	51.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	-	ko:K03642,ko:K07184	-	-	-	-	ko00000	-	-	-	CHAP,SH3_3,SH3_5
HSJS2_k127_2427525_1	926560.KE387027_gene366	1.301e-58	213.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS2_k127_2427525_0	926560.KE387027_gene366	2.989e-103	352.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS2_k127_2427525_3	926560.KE387023_gene3658	7.233e-11	73.0	COG0500@1|root,COG2226@2|Bacteria,1WMEJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2427525_2	552811.Dehly_1340	1.163e-32	133.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,34D3W@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HSJS2_k127_2429402_4	1121861.KB899912_gene987	6.908e-14	72.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSMN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	MA20_03535	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS2_k127_2429402_1	1096546.WYO_5033	5.417e-119	396.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,1JTBT@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	NADP oxidoreductase coenzyme F420-dependent	MA20_25935	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
HSJS2_k127_2429402_0	1123229.AUBC01000003_gene2054	5.14e-317	985.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria,3JQN2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
HSJS2_k127_2429402_2	1305737.JAFX01000001_gene2017	5.448e-78	274.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47KBZ@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
HSJS2_k127_2429402_3	1175306.GWL_41430	3.843e-51	188.0	COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472RR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM EAL domain, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
HSJS2_k127_2436789_2	298655.KI912266_gene2095	9.013e-32	135.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4EUVY@85013|Frankiales	201174|Actinobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HSJS2_k127_2436789_0	263358.VAB18032_12905	1.6e-164	547.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria,4D9TP@85008|Micromonosporales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
HSJS2_k127_2436789_3	926560.KE387028_gene210	5.441e-24	115.0	COG2380@1|root,COG2380@2|Bacteria,1WJ40@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2380 conserved	-	-	-	ko:K09785	-	-	-	-	ko00000	-	-	-	NurA
HSJS2_k127_2436789_1	479434.Sthe_2942	1.698e-44	171.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi,27YB5@189775|Thermomicrobia	189775|Thermomicrobia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HSJS2_k127_2437306_0	1120950.KB892769_gene5401	1.33e-107	357.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DNW9@85009|Propionibacteriales	201174|Actinobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HSJS2_k127_2437306_1	1229780.BN381_150106	9.552e-42	156.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,3UWT8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HSJS2_k127_2437306_2	351607.Acel_1564	2.326e-26	124.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4ERG2@85013|Frankiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
HSJS2_k127_2438124_2	483219.LILAB_19080	6.47e-58	211.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2WIZC@28221|Deltaproteobacteria,2YWY9@29|Myxococcales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
HSJS2_k127_2438124_1	266117.Rxyl_2393	5.478e-80	275.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria	201174|Actinobacteria	IQ	reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_2438124_0	292459.STH1186	1.18e-207	660.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia	186801|Clostridia	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HSJS2_k127_2438124_3	742738.HMPREF9460_00296	3.706e-31	130.0	COG2030@1|root,COG2030@2|Bacteria,1V6MY@1239|Firmicutes,24NB6@186801|Clostridia,26B2Z@186813|unclassified Clostridiales	186801|Clostridia	I	N-terminal half of MaoC dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
HSJS2_k127_2450642_3	1298863.AUEP01000008_gene1150	1.715e-24	109.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4DN00@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE30	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_2450642_5	1123388.AQWU01000053_gene1547	4.694e-05	49.0	COG2329@1|root,COG2329@2|Bacteria,1WNCW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HSJS2_k127_2450642_1	1415780.JPOG01000001_gene3309	6.614e-29	125.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales	135614|Xanthomonadales	S	Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
HSJS2_k127_2450642_0	1282876.BAOK01000001_gene1747	2.707e-54	205.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,2TWIW@28211|Alphaproteobacteria,4BTDE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS2_k127_2450642_4	469383.Cwoe_4525	1.803e-20	97.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4CQGU@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
HSJS2_k127_2450642_2	319003.Bra1253DRAFT_00172	1.255e-26	112.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria,3K512@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2455186_1	42256.RradSPS_1262	1.718e-104	348.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily. LDH family	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HSJS2_k127_2455186_0	414684.RC1_1865	3.083e-211	664.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2JP9U@204441|Rhodospirillales	204441|Rhodospirillales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
HSJS2_k127_2456229_4	272134.KB731324_gene6059	8.27e-51	192.0	COG1028@1|root,COG1028@2|Bacteria,1G4S8@1117|Cyanobacteria,1HC0U@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K19550	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572,M00787	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11067,R11671	RC00029,RC00117,RC03342	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_2456229_0	880072.Desac_2549	3.283e-77	266.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS2_k127_2456229_6	1009370.ALO_07618	1.535e-21	106.0	COG0614@1|root,COG0614@2|Bacteria,1UIJ9@1239|Firmicutes,4H2DE@909932|Negativicutes	909932|Negativicutes	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HSJS2_k127_2456229_2	1232428.CAVO010000014_gene752	1.736e-64	233.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4H33N@909932|Negativicutes	909932|Negativicutes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuG	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HSJS2_k127_2456229_1	1137271.AZUM01000002_gene2642	1.878e-69	244.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,4DZQ8@85010|Pseudonocardiales	201174|Actinobacteria	HP	ABC-type cobalamin Fe3 -siderophore transport system, ATPase component	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HSJS2_k127_2456229_8	224911.27354608	7.552e-09	67.0	2E474@1|root,32Z30@2|Bacteria,1NDQE@1224|Proteobacteria,2VFXZ@28211|Alphaproteobacteria,3K6HD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2456229_7	869210.Marky_0195	4.239e-09	68.0	COG1011@1|root,COG1011@2|Bacteria,1WK4M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
HSJS2_k127_2456229_5	383372.Rcas_1653	3.03e-23	107.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HSJS2_k127_2469583_3	1121481.AUAS01000002_gene3195	4.976e-14	74.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
HSJS2_k127_2469583_0	1150626.PHAMO_10089	5.081e-169	547.0	COG0702@1|root,COG0702@2|Bacteria,1PT91@1224|Proteobacteria,2U4IU@28211|Alphaproteobacteria,2JW5D@204441|Rhodospirillales	204441|Rhodospirillales	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
HSJS2_k127_2469583_1	543632.JOJL01000035_gene5071	1.477e-95	319.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2469583_2	448385.sce0600	7.951e-61	225.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,43F2R@68525|delta/epsilon subdivisions,2X35T@28221|Deltaproteobacteria,2YUDS@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
HSJS2_k127_2472663_1	1232410.KI421428_gene1178	4.493e-39	154.0	COG0596@1|root,COG0596@2|Bacteria,1RGAP@1224|Proteobacteria,42XWU@68525|delta/epsilon subdivisions,2WSMY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_2472663_0	309801.trd_A0786	3.292e-55	209.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,27YUJ@189775|Thermomicrobia	189775|Thermomicrobia	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HSJS2_k127_248749_6	1073999.BN137_3212	0.0007191	49.0	COG0454@1|root,COG0456@2|Bacteria,1N3P0@1224|Proteobacteria,1SB3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_248749_1	1303518.CCALI_00114	1.638e-116	390.0	COG0505@1|root,COG0505@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
HSJS2_k127_248749_0	552811.Dehly_0913	1.394e-135	445.0	COG0044@1|root,COG0044@2|Bacteria,2G640@200795|Chloroflexi,34CTM@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HSJS2_k127_248749_2	552811.Dehly_0912	1.35e-107	364.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi,34D9H@301297|Dehalococcoidia	301297|Dehalococcoidia	F	amino acid binding	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HSJS2_k127_248749_4	553204.CORAM0001_2150	2.425e-57	206.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,22KSE@1653|Corynebacteriaceae	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HSJS2_k127_248749_3	469383.Cwoe_5826	1.715e-62	226.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
HSJS2_k127_248749_5	1122603.ATVI01000009_gene2678	1.241e-29	128.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria	1224|Proteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
HSJS2_k127_2505726_2	1123504.JQKD01000040_gene2800	3.913e-17	93.0	COG0770@1|root,COG2843@1|root,COG4627@1|root,COG0770@2|Bacteria,COG2843@2|Bacteria,COG4627@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,4AEVE@80864|Comamonadaceae	28216|Betaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	Mur_ligase_M,PGA_cap
HSJS2_k127_2505726_0	861299.J421_0723	1.359e-49	188.0	COG2606@1|root,COG2606@2|Bacteria,1ZTSP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HSJS2_k127_2505726_1	399795.CtesDRAFT_PD5442	3.666e-36	143.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_2516289_3	479434.Sthe_1550	1.619e-10	71.0	COG0392@1|root,COG0392@2|Bacteria,2G6EN@200795|Chloroflexi,27Y9Q@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
HSJS2_k127_2516289_1	477974.Daud_2077	2.87e-84	299.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HSJS2_k127_2516289_0	1089553.Tph_c06510	2.806e-86	294.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,42EYC@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HSJS2_k127_2516289_4	644968.DFW101_2482	4.611e-05	49.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2M7VB@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
HSJS2_k127_2516289_2	1382306.JNIM01000001_gene1299	1.673e-76	274.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
HSJS2_k127_2535663_2	181119.XP_005531601.1	3.911e-47	181.0	COG0237@1|root,COG1019@1|root,KOG3220@2759|Eukaryota,KOG3351@2759|Eukaryota,38H33@33154|Opisthokonta,3BCJW@33208|Metazoa,3CSPG@33213|Bilateria,483JW@7711|Chordata,4918F@7742|Vertebrata,4GHJ6@8782|Aves	33208|Metazoa	H	Bifunctional coenzyme A synthase	COASY	GO:0000003,GO:0001667,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0003006,GO:0003674,GO:0003824,GO:0004140,GO:0004595,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005759,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007300,GO:0007303,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0010631,GO:0015936,GO:0015937,GO:0016020,GO:0016301,GO:0016310,GO:0016477,GO:0016482,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019867,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030707,GO:0030855,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040011,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046390,GO:0046483,GO:0046907,GO:0048468,GO:0048477,GO:0048513,GO:0048563,GO:0048569,GO:0048609,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0055086,GO:0055088,GO:0055090,GO:0060429,GO:0060562,GO:0065007,GO:0065008,GO:0070013,GO:0070328,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090130,GO:0090132,GO:0090407,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,2.7.7.3	ko:K02318	ko00770,ko01100,map00770,map01100	M00120	R00130,R03035	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,CoaE
HSJS2_k127_2535663_0	706587.Desti_0889	1.144e-106	354.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,42MX4@68525|delta/epsilon subdivisions,2WKVB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
HSJS2_k127_2535663_1	330214.NIDE3564	1.682e-47	196.0	COG4548@1|root,COG4548@2|Bacteria	2|Bacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
HSJS2_k127_2546105_2	469383.Cwoe_1902	1.792e-32	130.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HSJS2_k127_2546105_1	926569.ANT_05280	4.745e-41	161.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
HSJS2_k127_2546105_4	713586.KB900536_gene2264	4.78e-10	66.0	COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF302
HSJS2_k127_2546105_0	1122918.KB907249_gene3893	3.118e-49	184.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,26WSQ@186822|Paenibacillaceae	91061|Bacilli	C	CoA-transferase family III	frc	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_2547159_1	312284.A20C1_03353	1.87e-75	265.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2547159_3	749927.AMED_7853	9.156e-45	179.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DYSZ@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2547159_0	96561.Dole_0933	4.495e-88	305.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,42NUM@68525|delta/epsilon subdivisions,2WKR2@28221|Deltaproteobacteria,2MN4P@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 2-nitropropane dioxygenase NPD	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HSJS2_k127_2547159_2	479434.Sthe_2506	2.157e-65	244.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_2565182_2	392499.Swit_0205	1.779e-37	149.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2UFSH@28211|Alphaproteobacteria,2KBHV@204457|Sphingomonadales	204457|Sphingomonadales	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS2_k127_2565182_0	1280952.HJA_01920	4.765e-43	164.0	COG4308@1|root,COG4308@2|Bacteria,1RJ3T@1224|Proteobacteria,2UAH6@28211|Alphaproteobacteria,440IB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	Limonene-1,2-epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LEH
HSJS2_k127_2565182_5	357808.RoseRS_3658	2.619e-18	93.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8VB@200795|Chloroflexi,375FX@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trans_reg_C
HSJS2_k127_2565182_1	1463821.JOGR01000004_gene2451	7.709e-38	166.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4EZAK@85014|Glycomycetales	201174|Actinobacteria	KLT	PFAM Serine threonine protein kinase-related	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HSJS2_k127_2565182_4	1163408.UU9_04422	3.107e-28	124.0	COG3832@1|root,COG3832@2|Bacteria,1PH86@1224|Proteobacteria,1T8WT@1236|Gammaproteobacteria,1XBC8@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_2565182_3	1385518.N798_06590	1.505e-29	121.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4FHDK@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HSJS2_k127_2567641_0	1121396.KB892935_gene3861	2.526e-64	237.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_2567641_4	66874.JOFS01000025_gene1284	6.574e-16	85.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
HSJS2_k127_2567641_3	709986.Deima_2679	1.466e-19	96.0	COG0344@1|root,COG0344@2|Bacteria,1WJ35@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HSJS2_k127_2567641_1	290397.Adeh_1215	8.998e-47	186.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,43824@68525|delta/epsilon subdivisions,2X3C7@28221|Deltaproteobacteria,2YVD2@29|Myxococcales	28221|Deltaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
HSJS2_k127_2567641_2	479434.Sthe_2006	6.199e-36	150.0	COG0432@1|root,COG1304@1|root,COG0432@2|Bacteria,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
HSJS2_k127_2567641_5	1306174.JODP01000003_gene1860	0.0001641	52.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
HSJS2_k127_256782_1	357808.RoseRS_2027	2.121e-64	232.0	COG1167@1|root,COG1167@2|Bacteria,2G81Z@200795|Chloroflexi,376VD@32061|Chloroflexia	32061|Chloroflexia	EK	PFAM aminotransferase, class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HSJS2_k127_256782_2	926550.CLDAP_16180	4.509e-58	205.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
HSJS2_k127_256782_0	572477.Alvin_2800	3.644e-77	265.0	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1WW4H@135613|Chromatiales	135613|Chromatiales	J	PFAM methyltransferase small	-	-	-	-	-	-	-	-	-	-	-	-	MTS,MTS_N
HSJS2_k127_256782_3	28444.JODQ01000001_gene1945	3.295e-08	64.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4EHNT@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	phbB	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_2596456_0	314230.DSM3645_20632	8.912e-66	232.0	COG1201@1|root,COG1201@2|Bacteria,2IX0G@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
HSJS2_k127_2596456_4	58123.JOFJ01000018_gene4338	4.154e-22	104.0	COG1695@1|root,COG1695@2|Bacteria,2H1J3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS2_k127_2596456_2	1347369.CCAD010000086_gene1738	8.655e-50	183.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus	91061|Bacilli	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
HSJS2_k127_2596456_3	1411685.U062_01975	1.203e-27	115.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,1RNNH@1236|Gammaproteobacteria,1J607@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Esterase lipase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
HSJS2_k127_2596456_1	1205680.CAKO01000029_gene5115	7.512e-52	192.0	COG2141@1|root,COG2141@2|Bacteria,1R7GC@1224|Proteobacteria,2U0DW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_2605683_2	644966.Tmar_1857	2.148e-37	154.0	COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,25F1Y@186801|Clostridia,3WDUE@538999|Clostridiales incertae sedis	186801|Clostridia	E	PFAM FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
HSJS2_k127_2605683_8	1033806.HTIA_0933	1.209e-06	58.0	COG0589@1|root,arCOG03050@2157|Archaea,2XX2R@28890|Euryarchaeota,23VPA@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HSJS2_k127_2605683_5	1120949.KB903294_gene3809	6.574e-17	93.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2GN4Z@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
HSJS2_k127_2605683_6	118161.KB235922_gene5337	1.37e-13	81.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1GC8T@1117|Cyanobacteria	1117|Cyanobacteria	Q	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase
HSJS2_k127_2605683_1	1146883.BLASA_0805	2.232e-48	183.0	2F7BB@1|root,342EN@2|Bacteria	2|Bacteria	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
HSJS2_k127_2605683_4	1206720.BAFQ01000298_gene6852	1.733e-21	104.0	COG2267@1|root,COG2267@2|Bacteria,2I94I@201174|Actinobacteria,4FYKH@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
HSJS2_k127_2605683_3	443218.AS9A_4442	5.354e-36	160.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,234SY@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HSJS2_k127_2605683_0	234267.Acid_5780	2.809e-172	593.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
HSJS2_k127_2605683_7	339670.Bamb_4745	1.922e-11	65.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2VIMU@28216|Betaproteobacteria,1JZUC@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
HSJS2_k127_2612518_0	604331.AUHY01000007_gene691	2.206e-86	296.0	COG0492@1|root,COG0492@2|Bacteria,1WI0B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HSJS2_k127_2612518_1	1380356.JNIK01000002_gene4784	1.633e-72	263.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,4EUN0@85013|Frankiales	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2612518_2	485913.Krac_8091	3.784e-47	181.0	COG3393@1|root,COG3393@2|Bacteria,2G8JB@200795|Chloroflexi	200795|Chloroflexi	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
HSJS2_k127_2612518_3	1125863.JAFN01000001_gene1858	8.971e-22	99.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HSJS2_k127_2618227_4	479434.Sthe_1923	1.553e-68	240.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	DUF3500
HSJS2_k127_2618227_0	311424.DhcVS_740	1.496e-220	699.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi,34CZX@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HSJS2_k127_2618227_2	562970.Btus_0823	1.125e-128	424.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,2797K@186823|Alicyclobacillaceae	91061|Bacilli	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
HSJS2_k127_2618227_8	1267535.KB906767_gene2201	5.043e-44	165.0	COG0041@1|root,COG0041@2|Bacteria,3Y4MB@57723|Acidobacteria,2JJ9S@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HSJS2_k127_2618227_10	1120985.AUMI01000011_gene218	2.903e-15	83.0	COG1917@1|root,COG1917@2|Bacteria,1V7FN@1239|Firmicutes,4H6C3@909932|Negativicutes	909932|Negativicutes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS2_k127_2618227_1	479434.Sthe_1293	9.757e-150	485.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,27XJC@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HSJS2_k127_2618227_3	243164.DET0841	7.607e-95	321.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,34CSI@301297|Dehalococcoidia	301297|Dehalococcoidia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HSJS2_k127_2618227_9	555079.Toce_1504	2.703e-21	97.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,24R3W@186801|Clostridia,42H8G@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
HSJS2_k127_2618227_6	298655.KI912266_gene2037	8.071e-59	219.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4ERCV@85013|Frankiales	201174|Actinobacteria	G	PFAM Inositol monophosphatase	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HSJS2_k127_2618227_7	1128421.JAGA01000002_gene1394	1.224e-46	175.0	COG2039@1|root,COG2039@2|Bacteria,2NR9V@2323|unclassified Bacteria	2|Bacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
HSJS2_k127_2618227_5	1121861.KB899919_gene2798	3.653e-64	227.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2JPDI@204441|Rhodospirillales	204441|Rhodospirillales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HSJS2_k127_2618227_11	926550.CLDAP_22110	7.789e-06	49.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS2_k127_263537_1	1464048.JNZS01000021_gene2741	2.305e-40	155.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,4DA3T@85008|Micromonosporales	201174|Actinobacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
HSJS2_k127_263537_2	935948.KE386494_gene221	9.342e-11	69.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,42G6R@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00334,ko:K18330,ko:K22340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HSJS2_k127_263537_0	671143.DAMO_0854	1.73e-84	298.0	COG1894@1|root,COG1905@1|root,COG3411@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,COG3411@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoEF	-	1.12.1.3,1.17.1.9,1.6.5.3	ko:K00122,ko:K00335,ko:K17992	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
HSJS2_k127_2641584_6	1379698.RBG1_1C00001G0008	5.404e-11	69.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
HSJS2_k127_2641584_2	926550.CLDAP_18150	3.083e-48	186.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
HSJS2_k127_2641584_5	429009.Adeg_0654	5.333e-12	74.0	COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,42GTS@68295|Thermoanaerobacterales	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HSJS2_k127_2641584_0	357804.Ping_0949	3.574e-125	436.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QIXR@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
HSJS2_k127_2641584_1	479434.Sthe_1010	9.133e-51	200.0	COG0226@1|root,COG2843@1|root,COG0226@2|Bacteria,COG2843@2|Bacteria,2G78I@200795|Chloroflexi,27Z2P@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
HSJS2_k127_2641584_3	1123508.JH636442_gene4226	2.706e-28	117.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,RyR,TrkA_N
HSJS2_k127_2641584_4	543632.JOJL01000012_gene6673	1.531e-22	102.0	COG1917@1|root,COG1917@2|Bacteria,2IRRU@201174|Actinobacteria,4DJUR@85008|Micromonosporales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2648233_1	1416759.AYMR01000011_gene312	1.445e-68	238.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4FKGB@85023|Microbacteriaceae	201174|Actinobacteria	F	dCTP deaminase activity	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
HSJS2_k127_2648233_0	309801.trd_0502	1.007e-91	314.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2G5SW@200795|Chloroflexi,27XN2@189775|Thermomicrobia	189775|Thermomicrobia	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HSJS2_k127_2648233_2	500635.MITSMUL_03492	4.31e-51	187.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4H4M4@909932|Negativicutes	909932|Negativicutes	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HSJS2_k127_2648233_3	401053.AciPR4_1968	6.367e-38	146.0	COG0108@1|root,COG0108@2|Bacteria,3Y339@57723|Acidobacteria,2JIM0@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HSJS2_k127_2657427_1	926550.CLDAP_07190	6.588e-52	196.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
HSJS2_k127_2657427_0	479434.Sthe_0737	2.138e-165	546.0	COG1131@1|root,COG3420@1|root,COG1131@2|Bacteria,COG3420@2|Bacteria,2G7PN@200795|Chloroflexi,27Z0E@189775|Thermomicrobia	189775|Thermomicrobia	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	ABC_tran,NosD
HSJS2_k127_2657427_2	479434.Sthe_0736	1.611e-45	175.0	COG4314@1|root,COG4314@2|Bacteria,2G8NV@200795|Chloroflexi,27Z7G@189775|Thermomicrobia	189775|Thermomicrobia	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2670707_2	1037409.BJ6T_73470	2.296e-40	162.0	COG1011@1|root,COG1011@2|Bacteria,1PUN6@1224|Proteobacteria,2TY0G@28211|Alphaproteobacteria,3JU2Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HSJS2_k127_2670707_1	1304880.JAGB01000002_gene2026	3.637e-123	404.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HSJS2_k127_2670707_0	324602.Caur_3808	2.519e-126	411.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi,375C2@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HSJS2_k127_2688770_1	196162.Noca_2547	5.28e-55	204.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
HSJS2_k127_2688770_3	756883.Halar_2241	0.0003502	49.0	COG1977@1|root,arCOG06308@1|root,arCOG00536@2157|Archaea,arCOG06308@2157|Archaea	2157|Archaea	H	Mo-molybdopterin cofactor metabolic process	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HSJS2_k127_2688770_2	1464048.JNZS01000019_gene2354	2.995e-13	73.0	COG1977@1|root,COG1977@2|Bacteria,2I5HS@201174|Actinobacteria,4DE22@85008|Micromonosporales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HSJS2_k127_2688770_0	383372.Rcas_1863	3.528e-257	803.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi,376PZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
HSJS2_k127_2691169_2	1206741.BAFX01000064_gene5089	8.253e-64	233.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4FVHF@85025|Nocardiaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HSJS2_k127_2691169_1	502025.Hoch_6686	8.285e-82	287.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	HRDC domain protein	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
HSJS2_k127_2691169_0	1322246.BN4_12067	6.147e-139	465.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HSJS2_k127_2693878_4	1451261.AS96_04820	1.112e-62	233.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4FKT0@85023|Microbacteriaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
HSJS2_k127_2693878_7	1123322.KB904735_gene1530	4.759e-16	87.0	COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
HSJS2_k127_2693878_2	1043493.BBLU01000016_gene1503	6.05e-140	472.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HSJS2_k127_2693878_5	1392838.AWNM01000032_gene238	3.281e-44	173.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,3T48G@506|Alcaligenaceae	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_2693878_0	479434.Sthe_2041	3.664e-194	625.0	COG2936@1|root,COG2936@2|Bacteria,2G86S@200795|Chloroflexi	200795|Chloroflexi	S	X-Pro dipeptidyl-peptidase domain protein	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HSJS2_k127_2693878_1	1306990.BARG01000031_gene3438	5.636e-148	482.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS2_k127_2693878_6	861299.J421_2147	8.909e-29	126.0	COG3795@1|root,COG3795@2|Bacteria,1ZV0M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS2_k127_2693878_3	357808.RoseRS_3858	1.816e-86	298.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
HSJS2_k127_269473_2	760568.Desku_1070	7.899e-51	186.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,260R2@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
HSJS2_k127_269473_0	368407.Memar_1826	1.428e-106	360.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,2N9VR@224756|Methanomicrobia	224756|Methanomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HSJS2_k127_269473_1	1259795.ARJK01000002_gene31	3.623e-51	198.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_269473_3	1121377.KB906403_gene3068	2.753e-27	117.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS2_k127_2707485_1	1207063.P24_09626	5.696e-28	125.0	COG3346@1|root,COG3346@2|Bacteria,1MWWG@1224|Proteobacteria,2U0N5@28211|Alphaproteobacteria,2JSD9@204441|Rhodospirillales	204441|Rhodospirillales	S	SURF1-like protein	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
HSJS2_k127_2707485_0	1068978.AMETH_4561	9.872e-126	415.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4E0QR@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
HSJS2_k127_2707485_2	1123320.KB889669_gene3270	0.000176	44.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	fdxD	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
HSJS2_k127_2712954_6	661478.OP10G_0131	4.704e-06	52.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HSJS2_k127_2712954_3	292459.STH2458	3.506e-27	120.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
HSJS2_k127_2712954_0	266117.Rxyl_1110	4.381e-174	559.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
HSJS2_k127_2712954_5	1294143.H681_17225	4.826e-09	59.0	COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	protein conserved in bacteria	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
HSJS2_k127_2712954_1	1157490.EL26_00610	8.702e-88	293.0	COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,278B0@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase molybdopterin binding domain	yuiH	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
HSJS2_k127_2712954_4	1089548.KI783301_gene1156	1.005e-23	107.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3WETW@539002|Bacillales incertae sedis	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HSJS2_k127_2712954_2	243164.DET1375	2.637e-69	246.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,34D96@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HSJS2_k127_2718722_2	1242864.D187_008947	7.014e-16	91.0	COG3055@1|root,COG3055@2|Bacteria,1N3U2@1224|Proteobacteria,43AYV@68525|delta/epsilon subdivisions,2X6D5@28221|Deltaproteobacteria,2YYUW@29|Myxococcales	2|Bacteria	C	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4
HSJS2_k127_2718722_0	247490.KSU1_D0742	1.086e-209	667.0	COG0365@1|root,COG0365@2|Bacteria,2IX5P@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HSJS2_k127_2718722_1	400682.PAC_15710330	2.932e-162	544.0	COG0372@1|root,KOG2617@2759|Eukaryota,38E3U@33154|Opisthokonta,3BNEP@33208|Metazoa	33208|Metazoa	C	Citrate synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Citrate_synt
HSJS2_k127_2718722_3	1340493.JNIF01000003_gene2641	5.335e-09	63.0	2AYX9@1|root,31R2Z@2|Bacteria,3Y4ZH@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS2_k127_2724111_1	357808.RoseRS_0404	5.795e-69	245.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi,376DU@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HSJS2_k127_2724111_0	1128421.JAGA01000002_gene1414	2.433e-116	395.0	COG0769@1|root,COG0769@2|Bacteria,2NNZM@2323|unclassified Bacteria	2|Bacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS2_k127_2724111_8	675635.Psed_2486	2.941e-20	101.0	COG3871@1|root,COG3871@2|Bacteria,2HDER@201174|Actinobacteria	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2724111_2	926550.CLDAP_05980	1.471e-64	244.0	COG3842@1|root,COG3842@2|Bacteria,2G6S3@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE_2
HSJS2_k127_2724111_3	1121946.AUAX01000036_gene1878	8.851e-59	213.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4DAIP@85008|Micromonosporales	201174|Actinobacteria	P	molybdate ABC transporter, inner membrane subunit	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
HSJS2_k127_2724111_5	457429.ABJI02000129_gene2782	1.331e-33	139.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
HSJS2_k127_2724111_7	243164.DET0155	3.579e-22	111.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HSJS2_k127_2724111_6	1382306.JNIM01000001_gene3739	1.062e-30	127.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HSJS2_k127_2724111_10	1179226.AJXO01000056_gene1227	1.76e-12	69.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,4GZWG@90964|Staphylococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HSJS2_k127_2724111_4	717605.Theco_2138	1.227e-46	176.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,26QJX@186822|Paenibacillaceae	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HSJS2_k127_2728088_3	390989.JOEG01000011_gene200	1.891e-31	129.0	COG0748@1|root,COG0748@2|Bacteria,2IFHD@201174|Actinobacteria,4DDQ3@85008|Micromonosporales	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_2728088_0	634956.Geoth_1585	3.597e-75	269.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1WEA8@129337|Geobacillus	91061|Bacilli	I	Belongs to the thiolase family	pcaF	-	2.3.1.174,2.3.1.223	ko:K02615	ko00360,ko01120,map00360,map01120	-	R00829,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko01000	-	-	-	Thiolase_C,Thiolase_N
HSJS2_k127_2728088_4	439235.Dalk_3909	1.72e-24	110.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QX@1224|Proteobacteria,431N8@68525|delta/epsilon subdivisions,2WWXI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
HSJS2_k127_2728088_2	439235.Dalk_3908	7.483e-39	149.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QU@1224|Proteobacteria,431N3@68525|delta/epsilon subdivisions,2WWWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS2_k127_2728088_1	1123023.JIAI01000003_gene2846	4.539e-74	258.0	COG1028@1|root,COG1028@2|Bacteria,2H8QY@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS2_k127_2731437_2	710686.Mycsm_02651	2.264e-53	203.0	COG3178@1|root,COG3178@2|Bacteria,2GN8T@201174|Actinobacteria,23F8B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
HSJS2_k127_2731437_1	402881.Plav_1367	7.102e-62	228.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2U0CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
HSJS2_k127_2731437_4	710687.KI912270_gene5555	1.327e-06	61.0	2EHX5@1|root,33BNR@2|Bacteria,2GPW7@201174|Actinobacteria,23ARP@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2731437_0	1123024.AUII01000025_gene2125	1.133e-62	221.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
HSJS2_k127_2731437_3	253839.SSNG_05995	5.787e-07	59.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
HSJS2_k127_2745389_0	309801.trd_0459	4.862e-123	405.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G5QP@200795|Chloroflexi,27YNR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
HSJS2_k127_2745389_1	479433.Caci_4687	4.62e-08	64.0	COG1940@1|root,COG1940@2|Bacteria,2GNFJ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,MarR_2,ROK
HSJS2_k127_2745404_1	1211817.CCAT010000039_gene14	6.117e-37	150.0	COG0500@1|root,COG2226@2|Bacteria,1UJDM@1239|Firmicutes,24D7B@186801|Clostridia,36F5U@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS2_k127_2745404_0	926550.CLDAP_37620	6.248e-198	637.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HSJS2_k127_2766317_1	1121104.AQXH01000001_gene1475	3.394e-65	227.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
HSJS2_k127_2766317_4	1122138.AQUZ01000078_gene6116	6.451e-37	144.0	COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_2766317_0	309801.trd_0354	9.39e-124	412.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HSJS2_k127_2766317_2	1382306.JNIM01000001_gene527	8.89e-51	188.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HSJS2_k127_2766317_3	1146883.BLASA_2550	1.461e-46	186.0	COG2141@1|root,COG2141@2|Bacteria,2ICP1@201174|Actinobacteria,4EUVG@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_2771175_2	526225.Gobs_4662	2.266e-23	101.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4ERC4@85013|Frankiales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
HSJS2_k127_2771175_1	487316.BBNM01000006_gene2110	6.159e-104	343.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,3NII6@468|Moraxellaceae	1236|Gammaproteobacteria	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_2328	PAPS_reduct
HSJS2_k127_2771175_0	266117.Rxyl_0748	3.829e-115	381.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS2_k127_2773254_6	1303518.CCALI_01734	7.859e-10	65.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HSJS2_k127_2773254_2	656024.FsymDg_0299	1.31e-74	257.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EUES@85013|Frankiales	201174|Actinobacteria	T	response regulator	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_2773254_4	321327.CYA_0801	5.755e-33	144.0	COG0569@1|root,COG0569@2|Bacteria,1G0ZA@1117|Cyanobacteria,1GZ6I@1129|Synechococcus	1117|Cyanobacteria	P	COG0569 K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HSJS2_k127_2773254_3	1347392.CCEZ01000074_gene1908	2.716e-68	250.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,36DPR@31979|Clostridiaceae	186801|Clostridia	P	potassium uptake protein, TrkH family	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HSJS2_k127_2773254_1	1303518.CCALI_00857	1.873e-102	342.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
HSJS2_k127_2773254_5	1395587.P364_0100810	2.846e-16	81.0	COG3393@1|root,COG3393@2|Bacteria,1V9KV@1239|Firmicutes,4HJ79@91061|Bacilli,26YGF@186822|Paenibacillaceae	91061|Bacilli	S	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
HSJS2_k127_2773254_0	479434.Sthe_2294	4.02e-193	620.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
HSJS2_k127_2779896_2	671143.DAMO_0754	4.15e-103	344.0	COG0260@1|root,COG0260@2|Bacteria,2NNKH@2323|unclassified Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1,3.4.11.5	ko:K01255,ko:K01259	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00135,R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HSJS2_k127_2779896_5	1207058.L53_11265	7.862e-29	131.0	2E1KM@1|root,32WY3@2|Bacteria,1N5IW@1224|Proteobacteria,2UDKY@28211|Alphaproteobacteria,43ZXA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Methylmuconolactone methyl-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	EthD
HSJS2_k127_2779896_6	911045.PSE_4752	2.517e-09	66.0	COG0346@1|root,COG0346@2|Bacteria,1N810@1224|Proteobacteria,2UNCM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_2779896_7	360911.EAT1b_0572	5.855e-09	66.0	COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,4HG86@91061|Bacilli	91061|Bacilli	S	Belongs to the 5'(3')-deoxyribonucleotidase family	yqfW	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
HSJS2_k127_2779896_1	926569.ANT_11930	1.318e-103	350.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HSJS2_k127_2779896_4	484770.UFO1_0505	1.096e-78	275.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H2ZZ@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HSJS2_k127_2779896_0	1382356.JQMP01000003_gene1536	5.513e-119	398.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,27XP6@189775|Thermomicrobia	189775|Thermomicrobia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HSJS2_k127_2779896_3	1128421.JAGA01000002_gene1661	3.387e-95	322.0	COG0536@1|root,COG0536@2|Bacteria,2NNS6@2323|unclassified Bacteria	2|Bacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HSJS2_k127_2781297_0	1382306.JNIM01000001_gene3478	2.897e-122	416.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short
HSJS2_k127_2781297_1	485913.Krac_3768	4.963e-103	342.0	COG3316@1|root,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
HSJS2_k127_2785886_1	279238.Saro_3621	1.801e-38	160.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2K0PV@204457|Sphingomonadales	204457|Sphingomonadales	C	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2785886_3	247633.GP2143_02804	2.905e-12	78.0	COG2030@1|root,COG2030@2|Bacteria,1NYEM@1224|Proteobacteria	1224|Proteobacteria	I	dehydratase	MA20_27475	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2785886_2	1121106.JQKB01000065_gene5227	3.861e-31	139.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	28211|Alphaproteobacteria	C	III protein, CoA-transferase family	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2785886_0	931627.MycrhDRAFT_0691	5.405e-51	198.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,23518@1762|Mycobacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_2786801_3	1120934.KB894444_gene2480	9.598e-06	50.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria,4E5HN@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
HSJS2_k127_2786801_0	247633.GP2143_17211	4.277e-44	164.0	COG0346@1|root,COG0346@2|Bacteria,1Q6YP@1224|Proteobacteria,1SHXX@1236|Gammaproteobacteria,1JBPZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_2786801_1	1380390.JIAT01000011_gene2847	1.133e-40	159.0	COG1309@1|root,COG1309@2|Bacteria,2GNR9@201174|Actinobacteria,4CQDU@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HSJS2_k127_2786801_2	1206726.BAFV01000033_gene2328	1.211e-40	166.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,4G981@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
HSJS2_k127_2788069_0	1121033.AUCF01000001_gene2566	1.571e-132	428.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HSJS2_k127_2788069_2	479433.Caci_0426	8.553e-38	149.0	COG3871@1|root,COG3871@2|Bacteria,2GWY2@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_2788069_1	1380390.JIAT01000012_gene3177	2.364e-64	237.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,4CT1M@84995|Rubrobacteria	84995|Rubrobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
HSJS2_k127_2792810_5	237368.SCABRO_01193	1.928e-20	98.0	COG0674@1|root,COG0674@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HSJS2_k127_2792810_2	1382306.JNIM01000001_gene2603	7.271e-59	217.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi	200795|Chloroflexi	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
HSJS2_k127_2792810_4	1382306.JNIM01000001_gene2680	3.789e-34	137.0	COG0720@1|root,COG0720@2|Bacteria,2G919@200795|Chloroflexi	200795|Chloroflexi	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HSJS2_k127_2792810_3	326427.Cagg_1270	6.273e-41	166.0	COG0655@1|root,COG0655@2|Bacteria,2G9H8@200795|Chloroflexi,37812@32061|Chloroflexia	32061|Chloroflexia	S	NADPH-dependent FMN reductase	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
HSJS2_k127_2792810_1	765420.OSCT_2911	5.325e-109	379.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,375D2@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HSJS2_k127_2792810_0	909663.KI867150_gene1212	2.259e-118	387.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2MSIE@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS2_k127_2796611_1	405948.SACE_1347	2.057e-32	135.0	COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria,4E2QR@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	blaB3	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_2796611_3	1121861.KB899910_gene796	8.754e-16	86.0	COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,2UCBB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HSJS2_k127_2796611_0	710421.Mycch_0097	2.124e-56	206.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,2341D@1762|Mycobacteriaceae	201174|Actinobacteria	S	haloacid dehalogenase	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
HSJS2_k127_2796611_2	118173.KB235914_gene1178	1.999e-24	111.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HSJS2_k127_2797475_0	1157640.AQWO01000005_gene2159	4.88e-106	357.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS2_k127_2797475_1	1405296.Q499_0656	2.597e-45	172.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
HSJS2_k127_2797475_2	1220551.SCHR_02360	2.125e-15	83.0	COG1011@1|root,COG1011@2|Bacteria,1TPBK@1239|Firmicutes,4HS7S@91061|Bacilli,4GYCV@90964|Staphylococcaceae	91061|Bacilli	S	Hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HSJS2_k127_2797522_3	326297.Sama_3404	2.681e-17	97.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,2Q9Y9@267890|Shewanellaceae	1236|Gammaproteobacteria	S	UPF0761 membrane protein	rbn	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HSJS2_k127_2797522_1	552811.Dehly_0308	2.539e-108	362.0	COG0263@1|root,COG0263@2|Bacteria,2G67X@200795|Chloroflexi,34CYZ@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
HSJS2_k127_2797522_5	1449346.JQMO01000003_gene2557	7.146e-09	64.0	COG0645@1|root,COG0645@2|Bacteria,2IGXB@201174|Actinobacteria	201174|Actinobacteria	Q	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
HSJS2_k127_2797522_0	552811.Dehly_0299	9.573e-123	410.0	COG0014@1|root,COG0014@2|Bacteria,2G5TY@200795|Chloroflexi,34CYU@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HSJS2_k127_2797522_4	485913.Krac_6670	1.792e-14	78.0	2CJPB@1|root,33JM7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2797522_2	383372.Rcas_3992	2.908e-24	113.0	COG1011@1|root,COG1011@2|Bacteria,2G73G@200795|Chloroflexi,3760J@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HSJS2_k127_2801506_1	479434.Sthe_2682	6.945e-100	337.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HSJS2_k127_2801506_5	479434.Sthe_2681	2.248e-51	188.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi,27YA3@189775|Thermomicrobia	189775|Thermomicrobia	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HSJS2_k127_2801506_4	390989.JOEG01000001_gene5001	1.638e-63	228.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DEE4@85008|Micromonosporales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
HSJS2_k127_2801506_6	1121033.AUCF01000033_gene3628	3.571e-23	104.0	COG1695@1|root,COG1695@2|Bacteria,1N0PH@1224|Proteobacteria,2UBD4@28211|Alphaproteobacteria,2JT64@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS2_k127_2801506_7	1408424.JHYI01000013_gene1008	1.35e-11	72.0	COG4758@1|root,COG4758@2|Bacteria,1V9PN@1239|Firmicutes,4HMCU@91061|Bacilli,1ZQ0N@1386|Bacillus	91061|Bacilli	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
HSJS2_k127_2801506_8	1185876.BN8_01476	4.131e-05	49.0	COG1983@1|root,COG1983@2|Bacteria,4NRBJ@976|Bacteroidetes,47QNK@768503|Cytophagia	976|Bacteroidetes	KT	Phage shock protein C, PspC	-	-	-	-	-	-	-	-	-	-	-	-	PspC
HSJS2_k127_2801506_2	479434.Sthe_1775	4.296e-97	322.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS2_k127_2801506_0	479434.Sthe_1776	9.248e-185	626.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HSJS2_k127_2801506_3	869210.Marky_1283	1.418e-92	313.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1WIA7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HSJS2_k127_2810983_0	1038866.KB902791_gene3357	3.542e-165	531.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
HSJS2_k127_2810983_1	1123242.JH636436_gene718	1.368e-64	229.0	COG0566@1|root,COG0566@2|Bacteria,2J2FS@203682|Planctomycetes	203682|Planctomycetes	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
HSJS2_k127_2810983_2	1183438.GKIL_4161	3.463e-16	79.0	COG0488@1|root,COG0488@2|Bacteria,1G14R@1117|Cyanobacteria	1117|Cyanobacteria	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
HSJS2_k127_2827989_0	710111.FraQA3DRAFT_3338	3.107e-92	309.0	COG0604@1|root,COG0604@2|Bacteria,2GRJM@201174|Actinobacteria,4ETQB@85013|Frankiales	201174|Actinobacteria	C	Zn-dependent oxidoreductase, NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
HSJS2_k127_2827989_1	1137269.AZWL01000006_gene6755	1.179e-71	250.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_283051_0	379066.GAU_1314	0.0	1237.0	COG3696@1|root,COG3696@2|Bacteria,1ZUB0@142182|Gemmatimonadetes	2|Bacteria	P	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
HSJS2_k127_283051_2	497965.Cyan7822_1967	6.997e-05	49.0	COG2217@1|root,COG2217@2|Bacteria,1G0JR@1117|Cyanobacteria,3KFN4@43988|Cyanothece	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacS	GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HSJS2_k127_283051_1	1411123.JQNH01000001_gene3830	1.048e-78	271.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,2TZ7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
HSJS2_k127_2839622_3	1121946.AUAX01000017_gene5029	1.479e-05	50.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2GN4Z@201174|Actinobacteria,4DIF8@85008|Micromonosporales	201174|Actinobacteria	K	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
HSJS2_k127_2839622_0	1463853.JOHW01000015_gene169	2.131e-32	134.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria	201174|Actinobacteria	S	Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_2839622_1	388399.SSE37_09273	2.737e-20	99.0	COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,2TTR8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	3-methyladenine DNA glycosylase	MA20_23545	-	-	-	-	-	-	-	-	-	-	-	Adenine_glyco
HSJS2_k127_2839622_2	1123248.KB893321_gene567	7.509e-10	70.0	COG3291@1|root,COG3291@2|Bacteria,4P401@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_284084_6	977880.RALTA_A2273	0.0004293	44.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VNZF@28216|Betaproteobacteria,1K34S@119060|Burkholderiaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	caiB	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_284084_2	1229172.JQFA01000002_gene2209	3.104e-60	222.0	COG0524@1|root,COG0524@2|Bacteria,1G2YU@1117|Cyanobacteria,1H8FK@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HSJS2_k127_284084_4	439235.Dalk_2436	1.375e-23	108.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K22295	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
HSJS2_k127_284084_1	426117.M446_3426	1.773e-62	235.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,1JTCM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_284084_0	1206732.BAGD01000054_gene1961	1.012e-124	411.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_284084_3	512565.AMIS_24220	7.042e-45	179.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2GN4Z@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
HSJS2_k127_284084_5	485913.Krac_0871	5.992e-19	96.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_2853102_3	697284.ERIC2_c28870	2.157e-13	81.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,26QAN@186822|Paenibacillaceae	91061|Bacilli	S	Zn-dependent hydrolases, including glyoxylases	yqjP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_2853102_2	304371.MCP_2958	2.153e-20	102.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HSJS2_k127_2853102_4	1382356.JQMP01000003_gene2510	1.821e-08	61.0	COG1826@1|root,COG1826@2|Bacteria,2GAXB@200795|Chloroflexi,27YQN@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HSJS2_k127_2853102_5	1121373.KB903626_gene3248	0.0007536	51.0	COG3391@1|root,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
HSJS2_k127_2853102_1	926550.CLDAP_39560	4.037e-21	96.0	COG1975@1|root,COG1975@2|Bacteria	2|Bacteria	O	molybdopterin cofactor binding	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HSJS2_k127_2853102_0	1286171.EAL2_808p07250	1.563e-44	171.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,25WXN@186806|Eubacteriaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HSJS2_k127_285570_4	1504319.GM45_3185	9.456e-24	109.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,3UWRV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
HSJS2_k127_285570_0	635013.TherJR_2731	3.131e-181	586.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,260I5@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HSJS2_k127_285570_3	926569.ANT_19060	4.402e-53	198.0	COG2518@1|root,COG2518@2|Bacteria,2G6NG@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
HSJS2_k127_285570_1	311424.DhcVS_998	1.782e-85	296.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,34D04@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HSJS2_k127_285570_2	760568.Desku_3291	1.946e-54	196.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HSJS2_k127_2870979_3	388467.A19Y_3175	1.135e-36	146.0	COG2307@1|root,COG2307@2|Bacteria,1G05F@1117|Cyanobacteria,1H8SU@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial domain of	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
HSJS2_k127_2870979_2	517417.Cpar_0769	6.363e-37	155.0	COG1305@1|root,COG1305@2|Bacteria,1FEB8@1090|Chlorobi	1090|Chlorobi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
HSJS2_k127_2870979_1	761193.Runsl_5032	2.364e-73	256.0	COG3484@1|root,COG3484@2|Bacteria,4NGR7@976|Bacteroidetes,47MX7@768503|Cytophagia	976|Bacteroidetes	O	Proteasome subunit	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
HSJS2_k127_2870979_0	314230.DSM3645_19883	2.026e-211	668.0	COG0069@1|root,COG0069@2|Bacteria,2J28V@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the glutamate synthase family	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
HSJS2_k127_2877033_0	2074.JNYD01000003_gene3841	1.795e-81	274.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,4E22C@85010|Pseudonocardiales	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
HSJS2_k127_2877033_1	1121106.JQKB01000070_gene840	1.547e-53	196.0	COG1545@1|root,COG1545@2|Bacteria,1REY1@1224|Proteobacteria,2U8AE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_2877033_2	1089551.KE386572_gene2875	1.772e-52	197.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HSJS2_k127_2877033_3	861299.J421_5977	6.092e-43	165.0	COG0665@1|root,COG0665@2|Bacteria,1ZUQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
HSJS2_k127_2878906_0	552811.Dehly_0682	1.725e-191	618.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,34CSB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HSJS2_k127_2878906_9	469382.Hbor_16090	4.941e-29	125.0	arCOG09395@1|root,arCOG09395@2157|Archaea,2XTUR@28890|Euryarchaeota,23S6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS2_k127_2878906_10	869210.Marky_0620	6.667e-09	63.0	COG2128@1|root,COG2128@2|Bacteria,1WJ8T@1297|Deinococcus-Thermus	2|Bacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	CMD,DUF3179
HSJS2_k127_2878906_4	1382306.JNIM01000001_gene3511	3.897e-98	334.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HSJS2_k127_2878906_1	309801.trd_0508	4.051e-163	533.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
HSJS2_k127_2878906_6	525904.Tter_0080	4.427e-50	195.0	COG0341@1|root,COG0341@2|Bacteria,2NP4P@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HSJS2_k127_2878906_3	255470.cbdbA274	1.208e-100	344.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,34CQF@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
HSJS2_k127_2878906_11	887929.HMP0721_0235	1.919e-07	57.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,25WYU@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HSJS2_k127_2878906_7	552811.Dehly_0643	4.915e-44	167.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi,34CVZ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HSJS2_k127_2878906_2	552811.Dehly_1471	1.351e-155	525.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi,34D0F@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Helicase_C,ResIII
HSJS2_k127_2878906_8	639282.DEFDS_0250	7.627e-34	136.0	COG0335@1|root,COG0335@2|Bacteria,2GFPU@200930|Deferribacteres	200930|Deferribacteres	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HSJS2_k127_2878906_5	997346.HMPREF9374_0878	3.952e-60	212.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,27BNR@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA (Guanine-1)-methyltransferase	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HSJS2_k127_2880347_0	156889.Mmc1_2864	2.254e-20	95.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
HSJS2_k127_2885059_1	644283.Micau_0115	1.173e-24	111.0	COG0748@1|root,COG0748@2|Bacteria,2I6WT@201174|Actinobacteria,4DMTT@85008|Micromonosporales	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_2885059_0	477974.Daud_0835	8.595e-62	222.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,260XY@186807|Peptococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HSJS2_k127_2885059_2	1382358.JHVN01000002_gene2339	6.439e-08	56.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,21W76@150247|Anoxybacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS2_k127_2887094_2	479434.Sthe_1588	4.21e-05	53.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,27XNH@189775|Thermomicrobia	189775|Thermomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
HSJS2_k127_2887094_1	479434.Sthe_1589	3.485e-83	294.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,27XZ3@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS2_k127_2887094_0	357808.RoseRS_0692	2.028e-123	419.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS2_k127_2891844_0	552811.Dehly_1020	1.773e-194	622.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,34CN0@301297|Dehalococcoidia	301297|Dehalococcoidia	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HSJS2_k127_291322_1	1089553.Tph_c27030	6.027e-41	158.0	COG3653@1|root,COG3653@2|Bacteria,1TSGD@1239|Firmicutes,2482F@186801|Clostridia,42FYT@68295|Thermoanaerobacterales	186801|Clostridia	Q	Amidohydrolase family	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
HSJS2_k127_291322_3	1223523.H340_25402	9.301e-11	63.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
HSJS2_k127_291322_0	448385.sce3486	8.643e-109	368.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,42N4C@68525|delta/epsilon subdivisions,2WJIH@28221|Deltaproteobacteria,2YZWU@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
HSJS2_k127_291322_2	67267.JNXT01000011_gene975	9.448e-20	100.0	COG0526@1|root,COG0526@2|Bacteria,2HZTZ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS2_k127_292069_0	383372.Rcas_1109	2.912e-82	284.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_2930987_4	1118054.CAGW01000108_gene3625	9.542e-36	146.0	COG2227@1|root,COG2227@2|Bacteria,1UHU9@1239|Firmicutes,4HFRY@91061|Bacilli,277EV@186822|Paenibacillaceae	91061|Bacilli	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS2_k127_2930987_2	1128421.JAGA01000002_gene10	3.097e-57	214.0	COG0614@1|root,COG0614@2|Bacteria,2NPHH@2323|unclassified Bacteria	2|Bacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HSJS2_k127_2930987_0	552811.Dehly_0716	2.415e-88	304.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi,34CYV@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HSJS2_k127_2930987_1	1454010.JEOE01000009_gene3062	3.365e-61	221.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,4F1V6@85016|Cellulomonadaceae	201174|Actinobacteria	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HSJS2_k127_2930987_3	485913.Krac_2076	1.354e-44	169.0	COG2109@1|root,COG2109@2|Bacteria,2G6Q6@200795|Chloroflexi	200795|Chloroflexi	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
HSJS2_k127_2964620_4	525909.Afer_0375	2.574e-10	64.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CMUB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Protein synonym NADH dehydrogenase I subunit M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HSJS2_k127_2964620_1	485913.Krac_8280	1.82e-97	338.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HSJS2_k127_2964620_3	370438.PTH_0892	6.43e-28	119.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
HSJS2_k127_2964620_0	383372.Rcas_2293	1.121e-97	340.0	COG2812@1|root,COG3266@1|root,COG2812@2|Bacteria,COG3266@2|Bacteria,2G5PK@200795|Chloroflexi,37532@32061|Chloroflexia	32061|Chloroflexia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HSJS2_k127_2964620_2	479434.Sthe_0945	2.45e-64	225.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HSJS2_k127_2969839_5	381764.Fnod_0532	4.165e-05	46.0	COG0427@1|root,COG0427@2|Bacteria,2GCMB@200918|Thermotogae	200918|Thermotogae	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HSJS2_k127_2969839_1	1313172.YM304_29130	5.922e-92	316.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
HSJS2_k127_2969839_3	696747.NIES39_J03120	2.422e-76	270.0	COG4597@1|root,COG4597@2|Bacteria,1FZWE@1117|Cyanobacteria,1H6XP@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	bgtB	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
HSJS2_k127_2969839_2	1034347.CAHJ01000048_gene195	8.445e-77	284.0	COG0765@1|root,COG0765@2|Bacteria,1TRX4@1239|Firmicutes,4HEAH@91061|Bacilli,1ZQ16@1386|Bacillus	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
HSJS2_k127_2969839_0	926550.CLDAP_08240	1.612e-111	364.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
HSJS2_k127_2969839_4	1210046.B277_04747	4.237e-19	91.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,4FJJR@85021|Intrasporangiaceae	201174|Actinobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
HSJS2_k127_2995686_1	1111479.AXAR01000003_gene1515	2.232e-36	143.0	COG1853@1|root,COG1853@2|Bacteria,1V5M1@1239|Firmicutes,4HJWQ@91061|Bacilli	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
HSJS2_k127_2995686_0	469381.Dpep_0384	2.576e-43	175.0	COG0388@1|root,COG0388@2|Bacteria,3TC5X@508458|Synergistetes	508458|Synergistetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
HSJS2_k127_3001230_4	935948.KE386494_gene841	1.661e-24	110.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,24N37@186801|Clostridia,42GU4@68295|Thermoanaerobacterales	186801|Clostridia	S	Cyclic-di-AMP receptor	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
HSJS2_k127_3001230_3	1101192.KB910516_gene1764	5.468e-29	133.0	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,2TWW9@28211|Alphaproteobacteria,1JTEU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
HSJS2_k127_3001230_1	1125863.JAFN01000001_gene1846	3.465e-55	201.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_3001230_0	941824.TCEL_00696	5.98e-211	676.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,36G29@31979|Clostridiaceae	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
HSJS2_k127_3001230_6	330214.NIDE1088	1.51e-08	61.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
HSJS2_k127_3001230_5	1283299.AUKG01000002_gene4755	3.629e-22	100.0	COG0792@1|root,COG0792@2|Bacteria,2HP2Y@201174|Actinobacteria,4CQE0@84995|Rubrobacteria	84995|Rubrobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HSJS2_k127_3001230_2	290397.Adeh_0278	1.42e-47	179.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
HSJS2_k127_30041_1	525904.Tter_0301	2.047e-54	210.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
HSJS2_k127_30041_0	525904.Tter_0300	4.317e-70	244.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_30041_2	616991.JPOO01000001_gene4133	2.168e-29	127.0	COG3595@1|root,COG3595@2|Bacteria,4NNN5@976|Bacteroidetes,1I27D@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HSJS2_k127_3004147_0	485913.Krac_2996	2.365e-114	383.0	COG0667@1|root,COG0673@1|root,COG0667@2|Bacteria,COG0673@2|Bacteria,2G6AM@200795|Chloroflexi	200795|Chloroflexi	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS2_k127_3004147_5	394.NGR_a00350	0.0001938	48.0	COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria,4BDYZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional	QU41_21520	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HSJS2_k127_3004147_2	479434.Sthe_0535	1.482e-78	274.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,27XUY@189775|Thermomicrobia	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_3004147_3	1214101.BN159_4987	1.522e-53	198.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS2_k127_3004147_4	1123024.AUII01000006_gene4641	5.956e-12	71.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
HSJS2_k127_3004147_1	1122138.AQUZ01000056_gene6929	5.703e-87	293.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DPH5@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_3004524_3	187272.Mlg_2542	3.614e-28	121.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HSJS2_k127_3004524_2	596152.DesU5LDRAFT_0469	8.32e-30	129.0	COG0730@1|root,COG0730@2|Bacteria,1Q59Y@1224|Proteobacteria,430VR@68525|delta/epsilon subdivisions,2WVKN@28221|Deltaproteobacteria,2M8GD@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HSJS2_k127_3004524_0	882083.SacmaDRAFT_2041	2.109e-75	270.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EAD8@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3004524_1	882083.SacmaDRAFT_2041	2.737e-61	230.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EAD8@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3004524_5	29908.U7Q560	0.0001335	49.0	KOG4498@1|root,KOG4498@2759|Eukaryota,39UNE@33154|Opisthokonta,3NYQS@4751|Fungi,3QNUG@4890|Ascomycota,211AM@147550|Sordariomycetes,3USSQ@5151|Ophiostomatales	4751|Fungi	S	AhpC/TSA antioxidant enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
HSJS2_k127_3004524_4	1449353.JQMQ01000005_gene5424	3.205e-06	51.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria,2NGAN@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HSJS2_k127_3034768_2	1123269.NX02_06290	1.106e-07	56.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2TSTP@28211|Alphaproteobacteria,2K254@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_3034768_0	1282876.BAOK01000001_gene3210	3.265e-88	304.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2TUVX@28211|Alphaproteobacteria,4BT8D@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
HSJS2_k127_3034768_1	1449126.JQKL01000016_gene2873	1.016e-81	286.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia	186801|Clostridia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3034768_3	272943.RSP_3091	0.0008302	46.0	2E7ZW@1|root,332E8@2|Bacteria,1ND2G@1224|Proteobacteria,2UMS1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
HSJS2_k127_3044940_7	224308.BSU31030	8.974e-05	52.0	COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli,1ZR7U@1386|Bacillus	91061|Bacilli	S	DinB superfamily	yuaE	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS2_k127_3044940_1	456442.Mboo_2078	5.178e-34	143.0	COG2410@1|root,arCOG04409@2157|Archaea,2Y1Y7@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF429)	-	-	-	ko:K09147	-	-	-	-	ko00000	-	-	-	DUF429
HSJS2_k127_3044940_4	1449357.JQLK01000001_gene1307	1.604e-19	92.0	COG0607@1|root,COG0607@2|Bacteria,1WJ03@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HSJS2_k127_3044940_5	867845.KI911784_gene1328	6.207e-10	72.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
HSJS2_k127_3044940_2	1128421.JAGA01000002_gene1544	1.479e-25	114.0	COG2802@1|root,COG2802@2|Bacteria,2NPRK@2323|unclassified Bacteria	2|Bacteria	S	ATP-dependent protease La (LON) substrate-binding domain	lonD	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
HSJS2_k127_3044940_0	1110502.TMO_1021	1.102e-74	282.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,2JQ15@204441|Rhodospirillales	204441|Rhodospirillales	C	Formate dehydrogenase subunit alpha	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
HSJS2_k127_3044940_3	488538.SAR116_0149	1.197e-22	107.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,4BPG3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3,1.6.99.3	ko:K00338,ko:K03941	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	Fer4
HSJS2_k127_3044940_6	1094980.Mpsy_0196	7.76e-07	55.0	COG1234@1|root,arCOG00500@2157|Archaea,2XTUD@28890|Euryarchaeota,2NAES@224756|Methanomicrobia	224756|Methanomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HSJS2_k127_3049162_5	1424334.W822_21145	3.645e-50	187.0	COG0477@1|root,COG2814@2|Bacteria,1R8QG@1224|Proteobacteria,2VIBD@28216|Betaproteobacteria,3T2YU@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_3049162_3	404589.Anae109_0082	4.675e-99	339.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	peptidase, M16	MA20_05660	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS2_k127_3049162_0	313596.RB2501_15644	4.132e-147	479.0	COG0612@1|root,COG0612@2|Bacteria,4NE0K@976|Bacteroidetes,1HZQH@117743|Flavobacteriia	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS2_k127_3049162_2	479434.Sthe_3126	2.352e-109	377.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,27XTU@189775|Thermomicrobia	2|Bacteria	P	TrkA-C domain	nhaP	-	-	-	-	-	-	-	-	-	-	iJN678.sll0556	Na_H_Exchanger,TrkA_N
HSJS2_k127_3049162_7	485913.Krac_9334	1.685e-28	128.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
HSJS2_k127_3049162_6	1128421.JAGA01000001_gene2460	1.682e-36	151.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
HSJS2_k127_3049162_4	391600.ABRU01000041_gene2513	4.955e-60	224.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TS0V@28211|Alphaproteobacteria,2KHV5@204458|Caulobacterales	204458|Caulobacterales	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
HSJS2_k127_3049162_1	402881.Plav_1026	1.685e-111	372.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria,1JPBG@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HSJS2_k127_3057241_6	298654.FraEuI1c_2849	2.534e-25	113.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	ysnB	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HSJS2_k127_3057241_5	1454010.JEOE01000005_gene1702	6.544e-51	187.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
HSJS2_k127_3057241_2	1128421.JAGA01000002_gene1253	1.134e-102	352.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
HSJS2_k127_3057241_4	1449044.JMLE01000021_gene1964	1.771e-67	240.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria,1WADX@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
HSJS2_k127_3057241_1	1120950.KB892790_gene2100	4.961e-126	419.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4DMZ8@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HSJS2_k127_3057241_7	1122182.KB903835_gene4292	1.065e-10	74.0	COG0727@1|root,COG0727@2|Bacteria,2GZBY@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HSJS2_k127_3057241_3	1306990.BARG01000024_gene2646	3.819e-96	348.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3057241_0	1429916.X566_14870	6.638e-143	463.0	COG1024@1|root,COG1024@2|Bacteria	1429916.X566_14870|-	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3057241_8	316056.RPC_3084	1.926e-10	72.0	COG2030@1|root,COG2030@2|Bacteria,1NYEM@1224|Proteobacteria,2U0F4@28211|Alphaproteobacteria,3JVIY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	dehydratase	MA20_27475	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3057241_9	933115.GPDM_12691	2.01e-05	55.0	COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,26EWM@186818|Planococcaceae	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase family	ypmR	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HSJS2_k127_3066206_1	1382356.JQMP01000003_gene2367	1.114e-71	256.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi,27Y1X@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HSJS2_k127_3066206_0	1380394.JADL01000002_gene1116	1.13e-106	357.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,2JR0D@204441|Rhodospirillales	204441|Rhodospirillales	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS2_k127_3079028_2	1121934.AUDX01000022_gene2990	1.106e-11	66.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4FNNI@85023|Microbacteriaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	hrrA2	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_3079028_1	66874.JOFS01000043_gene128	2.399e-18	94.0	COG1595@1|root,COG2340@1|root,COG1595@2|Bacteria,COG2340@2|Bacteria,2GJ21@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Sigma70_r2
HSJS2_k127_3079028_4	797210.Halxa_0933	8.612e-07	61.0	COG2304@1|root,COG4801@1|root,arCOG02911@1|root,arCOG02471@2157|Archaea,arCOG02902@2157|Archaea,arCOG02911@2157|Archaea,2XUNN@28890|Euryarchaeota,23U32@183963|Halobacteria	183963|Halobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
HSJS2_k127_3079028_3	1267533.KB906742_gene685	2.501e-07	62.0	COG1361@1|root,COG3391@1|root,COG4409@1|root,COG1361@2|Bacteria,COG3391@2|Bacteria,COG4409@2|Bacteria,3Y768@57723|Acidobacteria,2JMB2@204432|Acidobacteriia	204432|Acidobacteriia	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573,SBBP
HSJS2_k127_3079028_0	1173026.Glo7428_2690	1.016e-81	282.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_3088248_4	1265502.KB905969_gene1230	1.682e-30	131.0	2C73B@1|root,330Z7@2|Bacteria,1N4FW@1224|Proteobacteria,2W6GV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3088248_5	1276756.AUEX01000002_gene449	1.152e-22	111.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VKM4@28216|Betaproteobacteria,4ACK9@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_3088248_3	1123504.JQKD01000012_gene1285	8.176e-55	209.0	COG1804@1|root,COG1804@2|Bacteria,1NSWZ@1224|Proteobacteria,2VPQF@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3088248_8	1121428.DESHY_160082___1	0.0001431	54.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,260BF@186807|Peptococcaceae	186801|Clostridia	M	Cell Wall	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,CW_binding_2,Cu_amine_oxidN1,SH3_3
HSJS2_k127_3088248_7	1121933.AUHH01000037_gene1498	2.727e-09	68.0	COG1102@1|root,COG1102@2|Bacteria,2I8J3@201174|Actinobacteria	201174|Actinobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HSJS2_k127_3088248_1	909663.KI867150_gene2380	1.762e-81	282.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
HSJS2_k127_3088248_2	479434.Sthe_3281	2.14e-62	228.0	COG0726@1|root,COG0726@2|Bacteria,2GB8A@200795|Chloroflexi,27XZW@189775|Thermomicrobia	189775|Thermomicrobia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HSJS2_k127_3088248_6	246197.MXAN_7387	8.08e-20	104.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
HSJS2_k127_3088248_0	926550.CLDAP_00380	3.996e-94	316.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HSJS2_k127_3095255_3	1297865.APJD01000009_gene2849	2.179e-42	158.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR0N@28211|Alphaproteobacteria,3JUIB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HSJS2_k127_3095255_1	634500.EbC_14490	8.014e-68	241.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,1RNBC@1236|Gammaproteobacteria,3X50A@551|Erwinia	1236|Gammaproteobacteria	P	permease	gsiD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	iECABU_c1320.ECABU_c08730,iECP_1309.ECP_0846,ic_1306.c0917	BPD_transp_1,OppC_N
HSJS2_k127_3095255_0	1297865.APJD01000009_gene2849	4.884e-84	291.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR0N@28211|Alphaproteobacteria,3JUIB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HSJS2_k127_3095255_2	1076550.LH22_15855	9.194e-60	217.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,1RNBC@1236|Gammaproteobacteria,3VY86@53335|Pantoea	1236|Gammaproteobacteria	EP	With GsiABD is involved in the transport of glutathione into the cell	gsiD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K13891	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	iECABU_c1320.ECABU_c08730,iECP_1309.ECP_0846,ic_1306.c0917	BPD_transp_1,OppC_N
HSJS2_k127_3110731_5	795359.TOPB45_1257	1.875e-12	70.0	COG0174@1|root,COG0174@2|Bacteria,2GH5N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HSJS2_k127_3110731_2	391625.PPSIR1_09715	3.225e-35	149.0	COG3386@1|root,COG3386@2|Bacteria,1P3IB@1224|Proteobacteria,43CN0@68525|delta/epsilon subdivisions,2X7V7@28221|Deltaproteobacteria,2Z22T@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3110731_3	1120934.KB894443_gene4248	1.074e-32	133.0	COG3832@1|root,COG3832@2|Bacteria,2I4FM@201174|Actinobacteria,4EDRA@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HSJS2_k127_3110731_6	255470.cbdbA489	2.767e-12	74.0	COG2030@1|root,COG2030@2|Bacteria,2G97V@200795|Chloroflexi,34DB1@301297|Dehalococcoidia	301297|Dehalococcoidia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS2_k127_3110731_4	439235.Dalk_3909	8.018e-25	111.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QX@1224|Proteobacteria,431N8@68525|delta/epsilon subdivisions,2WWXI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
HSJS2_k127_3110731_0	1385517.N800_12715	1.679e-41	163.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,1SE7M@1236|Gammaproteobacteria,1XC6D@135614|Xanthomonadales	135614|Xanthomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3110731_1	1131462.DCF50_p2293	7.723e-37	146.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HSJS2_k127_3127777_1	525904.Tter_1654	1.226e-104	347.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835,ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HSJS2_k127_3127777_0	552811.Dehly_1372	1.472e-115	386.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi,34CWB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	histidyl-tRNA aminoacylation	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HSJS2_k127_3127777_2	552811.Dehly_1359	2.918e-96	332.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,34CRS@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HSJS2_k127_3129661_0	469382.Hbor_06670	2.315e-101	338.0	COG2146@1|root,arCOG02852@2157|Archaea,2XUZH@28890|Euryarchaeota,23SZ3@183963|Halobacteria	183963|Halobacteria	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
HSJS2_k127_3129661_5	195250.CM001776_gene2883	1.813e-19	103.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1GYHE@1129|Synechococcus	1117|Cyanobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
HSJS2_k127_3129661_1	1040986.ATYO01000005_gene6122	6.797e-71	246.0	COG3896@1|root,COG3896@2|Bacteria,1NTZF@1224|Proteobacteria,2UQ7C@28211|Alphaproteobacteria,43PTV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
HSJS2_k127_3129661_8	1449346.JQMO01000002_gene631	1.38e-12	74.0	COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria,2M3AE@2063|Kitasatospora	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	ypeA	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HSJS2_k127_3129661_2	1089551.KE386572_gene2572	7.635e-39	154.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria,4BQIC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
HSJS2_k127_3129661_3	10228.TriadP20381	2.037e-34	138.0	KOG4059@1|root,KOG4059@2759|Eukaryota,3A621@33154|Opisthokonta,3BSXB@33208|Metazoa	33208|Metazoa	S	gamma-glutamylcyclotransferase activity	-	GO:0002376,GO:0003674,GO:0003824,GO:0003839,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007599,GO:0008150,GO:0009611,GO:0016829,GO:0016840,GO:0016842,GO:0032501,GO:0042060,GO:0042381,GO:0045087,GO:0050817,GO:0050878,GO:0050896,GO:0065007,GO:0065008	4.3.2.9	ko:K00682	ko00480,map00480	-	R02743,R03749	RC00064,RC00777	ko00000,ko00001,ko01000	-	-	-	AIG2_2
HSJS2_k127_3129661_4	1227453.C444_10259	1.692e-29	135.0	COG1653@1|root,arCOG00151@2157|Archaea,2Y2AY@28890|Euryarchaeota,23Z4Y@183963|Halobacteria	183963|Halobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3129661_6	1121017.AUFG01000031_gene371	3.103e-15	84.0	COG0454@1|root,COG0456@2|Bacteria,2IQC8@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_3129661_9	1121324.CLIT_4c02260	0.0005311	42.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,25R3D@186804|Peptostreptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HSJS2_k127_3133287_1	530564.Psta_4054	1.594e-62	224.0	COG2876@1|root,COG2876@2|Bacteria,2IWU9@203682|Planctomycetes	203682|Planctomycetes	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
HSJS2_k127_3133287_2	326427.Cagg_2934	2.597e-39	149.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi,375RY@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
HSJS2_k127_3133287_0	1128421.JAGA01000002_gene1341	1.129e-76	265.0	COG0159@1|root,COG0159@2|Bacteria,2NP9W@2323|unclassified Bacteria	2|Bacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HSJS2_k127_3133287_3	1396418.BATQ01000166_gene1904	9.781e-11	71.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,2IUVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HSJS2_k127_3136184_1	1268072.PSAB_16730	8.801e-70	244.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,26QP9@186822|Paenibacillaceae	91061|Bacilli	E	Xaa-Pro dipeptidase	yqhT	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HSJS2_k127_3136184_2	525904.Tter_1660	7.667e-57	204.0	COG0231@1|root,COG0231@2|Bacteria,2NPID@2323|unclassified Bacteria	2|Bacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HSJS2_k127_3136184_0	479434.Sthe_0789	4.266e-89	309.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi,27XEW@189775|Thermomicrobia	189775|Thermomicrobia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HSJS2_k127_3136184_4	1449063.JMLS01000004_gene2694	0.000119	54.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,27010@186822|Paenibacillaceae	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HSJS2_k127_3136184_3	311424.DhcVS_619	1.687e-56	206.0	COG0299@1|root,COG0299@2|Bacteria,2GANQ@200795|Chloroflexi,34CW6@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
HSJS2_k127_3142554_1	313612.L8106_12435	7.253e-87	300.0	COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria,1H9TR@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
HSJS2_k127_3142554_0	1382356.JQMP01000001_gene1198	3.983e-139	460.0	COG0028@1|root,COG0028@2|Bacteria,2GA3W@200795|Chloroflexi,27Z3I@189775|Thermomicrobia	189775|Thermomicrobia	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS2_k127_3142554_3	298655.KI912267_gene7788	8.879e-71	249.0	COG1028@1|root,COG1028@2|Bacteria	298655.KI912267_gene7788|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3142554_2	402881.Plav_0474	3.866e-76	265.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,1JNH3@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_3142554_5	561175.KB894094_gene1489	1.493e-27	125.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4EKKP@85012|Streptosporangiales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PAP2_3
HSJS2_k127_3142554_4	1313172.YM304_14770	2.356e-58	220.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
HSJS2_k127_3153422_1	1429916.X566_10260	1.552e-38	156.0	COG1024@1|root,COG1024@2|Bacteria,1NZ0X@1224|Proteobacteria	1224|Proteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS2_k127_3153422_0	1304865.JAGF01000001_gene2921	5.081e-94	316.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4F0HN@85016|Cellulomonadaceae	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter ATPase subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
HSJS2_k127_316611_2	931627.MycrhDRAFT_3102	2.496e-41	164.0	COG1024@1|root,COG1024@2|Bacteria,2HDTB@201174|Actinobacteria,2334H@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA2	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_316611_0	1333998.M2A_2255	2.262e-272	846.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,2TV2E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Flavoprotein involved in K transport	MA20_23085	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_2
HSJS2_k127_316611_1	1380390.JIAT01000013_gene145	3.767e-181	602.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
HSJS2_k127_3169613_1	1123023.JIAI01000001_gene7295	2.45e-64	225.0	COG0028@1|root,COG0028@2|Bacteria,2H36Z@201174|Actinobacteria	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS2_k127_3169613_4	1121931.AUHG01000019_gene3069	8.636e-07	54.0	2EPAC@1|root,33GX3@2|Bacteria,4P7SY@976|Bacteroidetes,1IBCN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3169613_0	1229780.BN381_300027	7.435e-215	692.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
HSJS2_k127_3169613_2	309801.trd_A0730	1.92e-32	135.0	COG1525@1|root,COG1525@2|Bacteria,2GBHE@200795|Chloroflexi,27YTT@189775|Thermomicrobia	189775|Thermomicrobia	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3169613_3	1283283.ATXA01000002_gene2776	1.354e-27	124.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4ERRT@85013|Frankiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_3170481_0	591158.SSMG_03458	1.298e-71	251.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria	201174|Actinobacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HSJS2_k127_3170481_2	273068.TTE2458	7.128e-51	198.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,42HX6@68295|Thermoanaerobacterales	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
HSJS2_k127_3170481_1	1380390.JIAT01000010_gene3531	8.655e-56	197.0	COG5649@1|root,COG5649@2|Bacteria,2HR6R@201174|Actinobacteria,4CT2N@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HSJS2_k127_3170481_3	1297742.A176_06526	5.057e-41	157.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42T8W@68525|delta/epsilon subdivisions,2WPDG@28221|Deltaproteobacteria,2YWUZ@29|Myxococcales	28221|Deltaproteobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS2_k127_3174498_4	204669.Acid345_0627	4.708e-05	49.0	COG2267@1|root,COG2267@2|Bacteria,3Y4Q6@57723|Acidobacteria,2JJ7I@204432|Acidobacteriia	204432|Acidobacteriia	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_3174498_2	370438.PTH_1335	3.976e-11	75.0	COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,24AIH@186801|Clostridia,260C4@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HSJS2_k127_3174498_1	1173028.ANKO01000197_gene6103	3.151e-12	78.0	COG2931@1|root,COG2931@2|Bacteria,1GQ5N@1117|Cyanobacteria,1HHU5@1150|Oscillatoriales	1117|Cyanobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3174498_0	1123309.AQYB01000030_gene1832	8.224e-144	468.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli	91061|Bacilli	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HSJS2_k127_3174498_3	80637.XP_007775460.1	2.845e-09	59.0	COG3663@1|root,KOG4120@2759|Eukaryota,38C6W@33154|Opisthokonta,3NUH6@4751|Fungi,3V23K@5204|Basidiomycota,229RS@155619|Agaricomycetes	4751|Fungi	L	DNA glycosylase	thp1	GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097507,GO:0097508,GO:0097509,GO:0140097,GO:1901360	3.2.2.29	ko:K20813	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HSJS2_k127_3176606_4	1173024.KI912148_gene3523	3.547e-35	137.0	COG2403@1|root,COG2403@2|Bacteria,1G1FF@1117|Cyanobacteria	1117|Cyanobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	cobW
HSJS2_k127_3176606_2	1148.1653943	1.58e-71	252.0	COG0549@1|root,COG0549@2|Bacteria,1GAQG@1117|Cyanobacteria	1117|Cyanobacteria	F	Belongs to the carbamate kinase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HSJS2_k127_3176606_1	926550.CLDAP_37300	2.329e-111	369.0	COG1064@1|root,COG1064@2|Bacteria,2G829@200795|Chloroflexi	200795|Chloroflexi	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
HSJS2_k127_3176606_7	926690.KE386573_gene1768	1.048e-11	72.0	COG0589@1|root,arCOG02053@2157|Archaea,2XX8Y@28890|Euryarchaeota,23VQJ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HSJS2_k127_3176606_3	640510.BC1001_2064	7.152e-62	232.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2VPBZ@28216|Betaproteobacteria,1K3AW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3176606_5	404380.Gbem_3170	4.413e-30	136.0	COG0500@1|root,COG2226@2|Bacteria,1NDFZ@1224|Proteobacteria,42R89@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	UbiE COQ5 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HSJS2_k127_3176606_0	1297865.APJD01000003_gene6063	1.049e-129	425.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TRM9@28211|Alphaproteobacteria,3K2PH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HSJS2_k127_3176606_6	644548.SCNU_09346	7.986e-22	102.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4GAIJ@85026|Gordoniaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
HSJS2_k127_3202652_2	243231.GSU3071	1.088e-10	74.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
HSJS2_k127_3202652_0	525904.Tter_1612	1.072e-94	325.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
HSJS2_k127_3202652_1	760568.Desku_1151	2.987e-83	291.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS2_k127_3203145_1	685727.REQ_07080	4.301e-07	62.0	COG0596@1|root,COG2197@1|root,COG0596@2|Bacteria,COG2197@2|Bacteria,2GN4Z@201174|Actinobacteria,4FW5A@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
HSJS2_k127_3203145_0	255470.cbdbA1441	2.147e-166	536.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,34CJD@301297|Dehalococcoidia	301297|Dehalococcoidia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HSJS2_k127_3203145_2	1408419.JHYG01000007_gene2969	3.175e-05	51.0	COG0494@1|root,COG1670@1|root,COG0494@2|Bacteria,COG1670@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria,2JS44@204441|Rhodospirillales	204441|Rhodospirillales	JL	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Acetyltransf_3,NUDIX,NUDIX_4
HSJS2_k127_3214258_2	324602.Caur_2333	1.395e-68	251.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,375DK@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HSJS2_k127_3214258_3	485913.Krac_8434	1.096e-05	50.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HSJS2_k127_3214258_1	251221.35214738	4.625e-112	377.0	COG0391@1|root,COG0391@2|Bacteria,1G0R0@1117|Cyanobacteria	1117|Cyanobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
HSJS2_k127_3214258_0	552811.Dehly_1476	4.225e-134	439.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi,34CT7@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HSJS2_k127_3229625_1	869210.Marky_1973	4.243e-24	110.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
HSJS2_k127_3229625_4	1263831.F543_6500	2.26e-05	53.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1Y8F5@135625|Pasteurellales	135625|Pasteurellales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
HSJS2_k127_3229625_0	479434.Sthe_1415	2.356e-151	502.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi,27Y17@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
HSJS2_k127_3229625_3	1238182.C882_3281	7.464e-09	69.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria,2JSQ1@204441|Rhodospirillales	204441|Rhodospirillales	P	subunit of a heme lyase	cycL	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
HSJS2_k127_3229625_2	309801.trd_0263	2.323e-15	88.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi,27XRI@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
HSJS2_k127_3239137_1	411154.GFO_2536	7.144e-29	116.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
HSJS2_k127_3239137_0	1283300.ATXB01000001_gene1800	6.088e-181	578.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XDMT@135618|Methylococcales	1236|Gammaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_3239137_3	37919.EP51_12550	2.694e-12	79.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,4G0VQ@85025|Nocardiaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
HSJS2_k127_3239137_2	304371.MCP_2201	2.67e-12	72.0	arCOG09612@1|root,arCOG09612@2157|Archaea,2Y4EU@28890|Euryarchaeota	28890|Euryarchaeota	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
HSJS2_k127_3269208_1	1120971.AUCA01000025_gene736	8.822e-20	94.0	COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli	91061|Bacilli	F	topology modulation protein	flaR	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HSJS2_k127_3269208_0	1457250.BBMO01000001_gene1129	2.734e-20	94.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HSJS2_k127_3273463_3	1370121.AUWS01000006_gene5137	5.978e-10	72.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,234SY@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HSJS2_k127_3273463_2	1125971.ASJB01000062_gene4429	8.141e-12	72.0	COG4758@1|root,COG4758@2|Bacteria,2HQN6@201174|Actinobacteria,4E9G5@85010|Pseudonocardiales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
HSJS2_k127_3273463_1	110319.CF8_1768	9.371e-79	280.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria,4DWK2@85009|Propionibacteriales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
HSJS2_k127_3273463_0	105422.BBPM01000001_gene4828	6.409e-151	497.0	COG0339@1|root,COG0339@2|Bacteria,2GM2Z@201174|Actinobacteria,2NF2Z@228398|Streptacidiphilus	201174|Actinobacteria	E	Peptidase family M3	-	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
HSJS2_k127_3280219_0	1120973.AQXL01000128_gene2869	2.327e-108	370.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,277XS@186823|Alicyclobacillaceae	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HSJS2_k127_3280219_2	867903.ThesuDRAFT_02262	4.045e-23	106.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3WCPZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HSJS2_k127_3280219_1	1205680.CAKO01000007_gene4412	3.249e-71	256.0	COG2141@1|root,COG2141@2|Bacteria,1NX0H@1224|Proteobacteria,2U42F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_3280219_3	479434.Sthe_1230	6.392e-23	99.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
HSJS2_k127_328279_1	767029.HMPREF9154_1169	1.02e-21	109.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4DR37@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4
HSJS2_k127_328279_2	105422.BBPM01000040_gene849	6.97e-15	79.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,2NJZ6@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
HSJS2_k127_328279_3	926550.CLDAP_09500	3.749e-05	53.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS2_k127_328279_0	237368.SCABRO_02061	4.524e-34	132.0	COG0172@1|root,COG0172@2|Bacteria,2IXGP@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HSJS2_k127_3288716_1	926550.CLDAP_15340	1.019e-61	230.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS2_k127_3288716_2	552811.Dehly_1038	8.034e-24	104.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,34DF5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HSJS2_k127_3288716_0	1232410.KI421420_gene3153	1.399e-171	554.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,43TFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HSJS2_k127_3293320_1	1035308.AQYY01000001_gene1561	1.864e-73	261.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,25E7R@186801|Clostridia,261MQ@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HSJS2_k127_3293320_0	243164.DET1417	6.127e-139	456.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,34CRG@301297|Dehalococcoidia	301297|Dehalococcoidia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HSJS2_k127_332612_1	101510.RHA1_ro11036	1.272e-33	143.0	COG1028@1|root,COG1028@2|Bacteria,2GIRG@201174|Actinobacteria,4FU04@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS2_k127_332612_0	196162.Noca_1184	4.374e-54	210.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4DVNT@85009|Propionibacteriales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
HSJS2_k127_3326322_0	269799.Gmet_1174	1.784e-160	549.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HSJS2_k127_332945_0	234267.Acid_5780	1.207e-94	347.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
HSJS2_k127_332945_1	1313172.YM304_07200	1.138e-40	175.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria	201174|Actinobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HSJS2_k127_332945_2	1463856.JOHY01000069_gene3542	1.28e-06	54.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
HSJS2_k127_3332579_2	485913.Krac_12392	1.815e-07	53.0	COG3316@1|root,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
HSJS2_k127_3332579_1	743525.TSC_c11650	8.576e-30	126.0	COG1765@1|root,COG1765@2|Bacteria,1WM1H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
HSJS2_k127_3332579_0	479431.Namu_0321	6.164e-93	324.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4ETB2@85013|Frankiales	201174|Actinobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
HSJS2_k127_3339628_0	1280949.HAD_06140	3.046e-104	350.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TQVS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HSJS2_k127_3339628_1	596152.DesU5LDRAFT_2535	4.568e-20	104.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42SAM@68525|delta/epsilon subdivisions,2WPCJ@28221|Deltaproteobacteria,2MD41@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HSJS2_k127_3339628_2	1192868.CAIU01000022_gene3198	4.259e-08	63.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp
HSJS2_k127_334173_1	555088.DealDRAFT_2906	2.845e-25	110.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes	1239|Firmicutes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
HSJS2_k127_334173_4	339670.Bamb_1317	1.07e-07	65.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,1K26R@119060|Burkholderiaceae	28216|Betaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
HSJS2_k127_334173_0	926569.ANT_25600	5.726e-26	119.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HSJS2_k127_334173_5	1122138.AQUZ01000014_gene7108	2.505e-05	57.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,4DQD5@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_334173_2	383372.Rcas_2498	2.689e-21	99.0	COG0748@1|root,COG0748@2|Bacteria,2GBMI@200795|Chloroflexi,3782F@32061|Chloroflexia	32061|Chloroflexia	P	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
HSJS2_k127_334173_3	1408473.JHXO01000009_gene3456	5.453e-21	95.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,2FMWZ@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HSJS2_k127_3342492_1	1128421.JAGA01000002_gene690	5.952e-64	221.0	COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria	2|Bacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HSJS2_k127_3342492_2	883078.HMPREF9695_02354	2.838e-55	197.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,3JS8U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HSJS2_k127_3342492_0	243231.GSU2860	2.721e-276	866.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HSJS2_k127_335281_3	479434.Sthe_3029	1.973e-36	144.0	COG0461@1|root,COG0461@2|Bacteria,2G7HB@200795|Chloroflexi,27XKH@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HSJS2_k127_335281_0	316274.Haur_3884	1.699e-119	396.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,3751V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HSJS2_k127_335281_1	439235.Dalk_5191	4.363e-65	247.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	1224|Proteobacteria	C	PFAM CoA-binding domain protein	MA20_15065	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
HSJS2_k127_335281_2	765177.Desmu_0132	4.483e-63	228.0	COG1042@1|root,arCOG01338@2157|Archaea,2XQ9M@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM ATP-grasp domain	-	-	6.2.1.13	ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5
HSJS2_k127_3361181_1	1174528.JH992898_gene733	1.443e-88	302.0	COG2146@1|root,COG2146@2|Bacteria,1G2KG@1117|Cyanobacteria,1JK9R@1189|Stigonemataceae	1117|Cyanobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
HSJS2_k127_3361181_0	479432.Sros_4171	1.39e-116	391.0	COG0654@1|root,COG0654@2|Bacteria,2I901@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,NAD_binding_8,Trp_halogenase
HSJS2_k127_3369070_2	479434.Sthe_1073	1.47e-61	219.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HSJS2_k127_3369070_0	479434.Sthe_0838	9.208e-101	338.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi,27XGA@189775|Thermomicrobia	189775|Thermomicrobia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HSJS2_k127_3369070_1	1380390.JIAT01000009_gene671	1.469e-87	309.0	COG0477@1|root,COG2814@2|Bacteria,2I2DZ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HSJS2_k127_3369070_3	316274.Haur_2160	2.071e-27	121.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
HSJS2_k127_3373799_1	311424.DhcVS_989	3.671e-69	244.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi,34D8M@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
HSJS2_k127_3373799_0	358681.BBR47_18550	2.449e-121	409.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,26RAH@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06615,iYO844.BSU32250	PALP
HSJS2_k127_3404646_3	937774.TEQUI_0378	2.12e-25	120.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2VIGP@28216|Betaproteobacteria,3T2YV@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	gsiD	-	-	ko:K13891	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1,OppC_N
HSJS2_k127_3404646_1	1297617.JPJD01000007_gene68	1.142e-70	250.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,268J5@186813|unclassified Clostridiales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HSJS2_k127_3404646_4	1123229.AUBC01000007_gene155	2.009e-22	113.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TS14@28211|Alphaproteobacteria,3JQM3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	MA20_19540	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HSJS2_k127_3404646_5	1279017.AQYJ01000026_gene73	1.43e-15	85.0	2DXTJ@1|root,346GW@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3404646_2	287986.DV20_02125	4.516e-28	119.0	COG0346@1|root,COG0346@2|Bacteria,2H5Y5@201174|Actinobacteria,4EBMJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_3404646_0	485913.Krac_2859	9.076e-75	265.0	COG2141@1|root,COG2141@2|Bacteria,2G869@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_3418984_0	439235.Dalk_4476	2.477e-114	388.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42PUP@68525|delta/epsilon subdivisions,2WMAH@28221|Deltaproteobacteria,2MN7Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
HSJS2_k127_3418984_1	309801.trd_1505	8.49e-95	326.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS2_k127_3434021_4	357808.RoseRS_3756	1.526e-49	181.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HSJS2_k127_3434021_1	926550.CLDAP_22390	9.527e-120	397.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HSJS2_k127_3434021_2	926569.ANT_13120	1.202e-117	400.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HSJS2_k127_3434021_0	202752.JL53_12175	3.989e-139	453.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26IT7@186820|Listeriaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
HSJS2_k127_3434021_3	1449126.JQKL01000022_gene140	4.059e-75	257.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,267N3@186813|unclassified Clostridiales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HSJS2_k127_3441645_1	1232683.ADIMK_3584	1.683e-126	417.0	COG0025@1|root,COG0664@1|root,COG0025@2|Bacteria,COG0664@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,467E9@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0025 NhaP-type Na H and K H antiporters	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
HSJS2_k127_3442706_2	1229203.KI301992_gene138	3.505e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,2HG2Z@201174|Actinobacteria,3UXS2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
HSJS2_k127_3442706_4	1463825.JNXC01000047_gene6739	4.897e-15	79.0	COG0346@1|root,COG0346@2|Bacteria,2INT0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3442706_3	1206720.BAFQ01000141_gene3559	6.473e-18	91.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,4G35H@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
HSJS2_k127_3442706_1	221288.JH992901_gene3818	3.905e-28	128.0	COG3386@1|root,COG3386@2|Bacteria,1GBCW@1117|Cyanobacteria	1117|Cyanobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3442706_0	1054860.KB913030_gene3513	3.003e-35	146.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp20	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
HSJS2_k127_3446021_3	1229172.JQFA01000002_gene4566	7.349e-25	106.0	COG1610@1|root,COG1610@2|Bacteria,1G607@1117|Cyanobacteria,1HB1I@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HSJS2_k127_3446021_1	264732.Moth_0594	2.053e-93	335.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,42EY4@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
HSJS2_k127_3446021_2	1121428.DESHY_70012___1	2.755e-74	267.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,260V1@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HSJS2_k127_3446021_0	1232449.BAHV02000014_gene2025	1.896e-94	319.0	COG0069@1|root,COG0069@2|Bacteria,1TPVM@1239|Firmicutes,2487M@186801|Clostridia	186801|Clostridia	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rubredoxin
HSJS2_k127_3447625_0	935839.JAGJ01000023_gene2460	4.324e-83	283.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4F40W@85017|Promicromonosporaceae	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
HSJS2_k127_3447625_6	1128421.JAGA01000002_gene980	3.962e-10	66.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	thiX	-	1.8.1.8	ko:K02199,ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
HSJS2_k127_3447625_2	1128421.JAGA01000002_gene979	7.828e-34	135.0	2DMUR@1|root,32TTD@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
HSJS2_k127_3447625_1	479434.Sthe_0899	1.301e-71	252.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi,27XQ4@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
HSJS2_k127_3447625_5	411471.SUBVAR_05136	1.963e-26	112.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HSJS2_k127_3447625_3	1117647.M5M_08730	1.604e-31	125.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1J6MX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HSJS2_k127_3447625_4	926550.CLDAP_20650	4.814e-27	114.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi	200795|Chloroflexi	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HSJS2_k127_3447625_7	573.JG24_17205	2.609e-09	68.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1S274@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	yohD	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HSJS2_k127_3458152_6	1380347.JNII01000005_gene2882	3.77e-06	59.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,2GPF1@201174|Actinobacteria	201174|Actinobacteria	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
HSJS2_k127_3458152_4	1500893.JQNB01000001_gene227	4.941e-11	71.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1X3RK@135614|Xanthomonadales	135614|Xanthomonadales	L	ADP-ribose diphosphatase	nudE	-	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HSJS2_k127_3458152_1	1030157.AFMP01000040_gene1551	4.425e-114	387.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSZ8@28211|Alphaproteobacteria,2K8YM@204457|Sphingomonadales	204457|Sphingomonadales	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS2_k127_3458152_2	1206732.BAGD01000054_gene1961	1.922e-105	355.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_3458152_3	118166.JH976537_gene4259	1.295e-43	168.0	COG3217@1|root,COG3217@2|Bacteria,1G2HY@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain containing protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
HSJS2_k127_3458152_0	9031.ENSGALP00000026689	4.154e-117	386.0	COG0596@1|root,COG1011@1|root,KOG3085@2759|Eukaryota,KOG4178@2759|Eukaryota,39WAD@33154|Opisthokonta,3BACN@33208|Metazoa,3CVBC@33213|Bilateria,482KF@7711|Chordata,48X7C@7742|Vertebrata,4GKMZ@8782|Aves	33208|Metazoa	I	Epoxide hydrolase 2	EPHX2	GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006633,GO:0006690,GO:0006725,GO:0006793,GO:0006796,GO:0006805,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007031,GO:0007600,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008217,GO:0008610,GO:0009056,GO:0009058,GO:0009410,GO:0009636,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015031,GO:0015643,GO:0015833,GO:0016043,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0017144,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019369,GO:0019373,GO:0019439,GO:0019725,GO:0019752,GO:0030003,GO:0030258,GO:0031907,GO:0031974,GO:0032501,GO:0032787,GO:0033036,GO:0033365,GO:0033559,GO:0034613,GO:0035150,GO:0035296,GO:0042221,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042759,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045777,GO:0046272,GO:0046394,GO:0046483,GO:0046839,GO:0046872,GO:0046907,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050801,GO:0050877,GO:0050880,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070887,GO:0071466,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072330,GO:0072503,GO:0072507,GO:0072593,GO:0072594,GO:0072662,GO:0072663,GO:0080090,GO:0090066,GO:0090181,GO:0097176,GO:0097746,GO:0097755,GO:0098771,GO:1900673,GO:1901360,GO:1901361,GO:1901568,GO:1901575,GO:1901576	3.1.3.76,3.3.2.10	ko:K08726,ko:K10089	ko00590,ko00625,ko01100,ko01120,ko04142,ko04145,ko04146,map00590,map00625,map01100,map01120,map04142,map04145,map04146	-	R05842,R07108,R07109,R07110,R07111	RC01477,RC01757	ko00000,ko00001,ko01000,ko01002,ko01009,ko04091,ko04147	-	-	-	Abhydrolase_1,HAD_2
HSJS2_k127_3458152_5	234831.PSM_B0538	1.7e-06	50.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,2Q2Q4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HSJS2_k127_3468516_2	1235279.C772_00536	2.715e-75	259.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26D04@186818|Planococcaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
HSJS2_k127_3468516_1	255470.cbdbA313	2.025e-87	303.0	COG0750@1|root,COG0750@2|Bacteria,2G6HV@200795|Chloroflexi,34D8H@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
HSJS2_k127_3468516_0	472759.Nhal_1234	1.068e-155	507.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1WW8H@135613|Chromatiales	135613|Chromatiales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
HSJS2_k127_3468516_4	237368.SCABRO_00336	3.444e-25	118.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
HSJS2_k127_3468516_3	243164.DET0368	1.011e-56	201.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi,34CJ8@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
HSJS2_k127_3481103_0	479434.Sthe_1429	1.621e-132	432.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,27XSS@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HSJS2_k127_3481103_1	195250.CM001776_gene3808	1.806e-09	60.0	COG0019@1|root,COG0019@2|Bacteria,1G1S7@1117|Cyanobacteria,1GYGU@1129|Synechococcus	1117|Cyanobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HSJS2_k127_3487153_2	1293054.HSACCH_00450	2.529e-13	74.0	COG2128@1|root,COG2128@2|Bacteria,1UVG3@1239|Firmicutes	1239|Firmicutes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HSJS2_k127_3487153_4	1033810.HLPCO_002949	8.066e-08	61.0	COG2128@1|root,COG2128@2|Bacteria,2NS09@2323|unclassified Bacteria	2|Bacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HSJS2_k127_3487153_1	1122247.C731_1921	3.677e-43	175.0	COG3178@1|root,COG3178@2|Bacteria,2GN8T@201174|Actinobacteria,23F8B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
HSJS2_k127_3487153_0	795797.C497_05402	5.331e-53	194.0	COG0154@1|root,arCOG01717@2157|Archaea,2XV02@28890|Euryarchaeota,23TIC@183963|Halobacteria	183963|Halobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HSJS2_k127_3487153_3	1449126.JQKL01000004_gene620	2.503e-11	63.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2689E@186813|unclassified Clostridiales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
HSJS2_k127_3498628_1	557598.LHK_02557	1.438e-98	342.0	COG2905@1|root,COG5001@1|root,COG2905@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQJ6@206351|Neisseriales	206351|Neisseriales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
HSJS2_k127_3498628_5	34007.IT40_22225	2.355e-11	73.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2PVBQ@265|Paracoccus	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HSJS2_k127_3498628_2	388413.ALPR1_14479	1.476e-78	276.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47K2Q@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
HSJS2_k127_3498628_0	67275.JOAP01000002_gene7084	1.783e-144	479.0	COG3391@1|root,COG3391@2|Bacteria,2IBCA@201174|Actinobacteria	201174|Actinobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
HSJS2_k127_3498628_3	1111479.AXAR01000001_gene21	3.223e-32	131.0	COG1853@1|root,COG1853@2|Bacteria,1V1X6@1239|Firmicutes,4HGJ2@91061|Bacilli,279EA@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HSJS2_k127_3498628_4	709986.Deima_0684	7.18e-15	76.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1WMTI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	FL	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
HSJS2_k127_3499800_0	1380394.JADL01000007_gene4673	2.006e-105	347.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	28211|Alphaproteobacteria	C	III protein, CoA-transferase family	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3499800_2	1214101.BN159_1370	1.386e-78	270.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	MA20_13990	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	Lactamase_B
HSJS2_k127_3499800_3	767817.Desgi_3217	2.267e-78	271.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,25EG6@186801|Clostridia,265GT@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_3499800_4	1267534.KB906755_gene4315	6.738e-51	197.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria,2JK6X@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
HSJS2_k127_3499800_1	42256.RradSPS_2515	6.268e-99	333.0	COG1522@1|root,COG1522@2|Bacteria,2IIXK@201174|Actinobacteria,4CPCF@84995|Rubrobacteria	84995|Rubrobacteria	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
HSJS2_k127_3502018_2	1122622.ATWJ01000014_gene301	3.189e-31	127.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4FE3B@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
HSJS2_k127_3502018_1	1128421.JAGA01000001_gene2435	1.875e-106	364.0	COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
HSJS2_k127_3502018_0	926550.CLDAP_08170	3.291e-117	385.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HSJS2_k127_3520393_3	443144.GM21_0509	1.544e-15	90.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS2_k127_3520393_2	324602.Caur_0755	3.757e-63	243.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi,374ZS@32061|Chloroflexia	32061|Chloroflexia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HSJS2_k127_3520393_0	1089553.Tph_c12630	1.61e-91	317.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,42EPV@68295|Thermoanaerobacterales	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HSJS2_k127_3520393_1	926569.ANT_23360	1.353e-83	292.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HSJS2_k127_3525602_3	1122927.KB895414_gene4927	2.228e-49	190.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,4HE5R@91061|Bacilli,274YW@186822|Paenibacillaceae	91061|Bacilli	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
HSJS2_k127_3525602_4	247639.MGP2080_08529	6.204e-46	184.0	2DBU1@1|root,2ZB3C@2|Bacteria,1NB4B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3525602_5	176946.XP_007434795.1	5.843e-06	59.0	KOG1565@1|root,KOG1565@2759|Eukaryota,39HBF@33154|Opisthokonta,3BKAC@33208|Metazoa,3D46B@33213|Bilateria,482MG@7711|Chordata,498XQ@7742|Vertebrata	33208|Metazoa	OW	Matrixin	MMP27	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0012505,GO:0016020,GO:0019898,GO:0031090,GO:0031312,GO:0031984,GO:0042175,GO:0042406,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0098827	3.4.24.34	ko:K01402,ko:K07994,ko:K08005	ko04657,ko04926,map04657,map04926	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
HSJS2_k127_3525602_1	867845.KI911784_gene3297	2.843e-83	293.0	COG1169@1|root,COG1169@2|Bacteria,2G5RQ@200795|Chloroflexi,375P4@32061|Chloroflexia	32061|Chloroflexia	HQ	TIGRFAM isochorismate synthase	-	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
HSJS2_k127_3525602_0	309801.trd_A0261	1.041e-157	521.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
HSJS2_k127_3525602_2	479434.Sthe_3023	3.689e-80	274.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
HSJS2_k127_3534528_0	479431.Namu_1612	8.059e-72	248.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4EVC6@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
HSJS2_k127_3534528_2	1168059.KB899087_gene1061	6.944e-10	63.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HSJS2_k127_3534528_1	644283.Micau_2845	1.101e-38	152.0	COG2242@1|root,COG2242@2|Bacteria,2IAR0@201174|Actinobacteria,4D9FM@85008|Micromonosporales	201174|Actinobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3536083_2	1260251.SPISAL_07725	1.339e-17	89.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
HSJS2_k127_3536083_1	574966.KB898647_gene2566	8.814e-35	143.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC,ZnuA
HSJS2_k127_3536083_0	518766.Rmar_2012	1.514e-278	871.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HSJS2_k127_3536999_3	479434.Sthe_2975	1.303e-27	118.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,27XKB@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC 3 transport family	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
HSJS2_k127_3536999_6	556269.ACDQ01000003_gene1382	6.496e-07	60.0	COG2050@1|root,COG2050@2|Bacteria,1RDVV@1224|Proteobacteria,2WCGG@28216|Betaproteobacteria,477JP@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HSJS2_k127_3536999_4	1121382.JQKG01000005_gene3326	1.354e-22	102.0	COG1733@1|root,COG1733@2|Bacteria,1WJYB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HSJS2_k127_3536999_5	862751.SACTE_1140	4.817e-07	59.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS2_k127_3536999_2	309801.trd_1308	3.923e-29	128.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi,27Z8E@189775|Thermomicrobia	189775|Thermomicrobia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HSJS2_k127_3536999_0	248742.XP_005644623.1	2.611e-80	287.0	2CWGT@1|root,2S4IK@2759|Eukaryota,37ZNN@33090|Viridiplantae,34KHX@3041|Chlorophyta	3041|Chlorophyta	S	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HSJS2_k127_3536999_1	309801.trd_1056	2.686e-33	131.0	COG0686@1|root,COG0686@2|Bacteria,2G68X@200795|Chloroflexi,27YU4@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HSJS2_k127_3550454_0	552811.Dehly_0915	7.803e-313	974.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,34D66@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HSJS2_k127_3550454_3	1121430.JMLG01000008_gene1543	9.927e-24	116.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,24GK6@186801|Clostridia,261XX@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	ppaX	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HSJS2_k127_3550454_1	243164.DET1203	6.777e-53	197.0	COG0543@1|root,COG0543@2|Bacteria,2G75X@200795|Chloroflexi,34D0J@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
HSJS2_k127_3550454_4	1173023.KE650771_gene5107	1.659e-18	98.0	COG1432@1|root,COG1432@2|Bacteria,1G3J6@1117|Cyanobacteria,1JHFM@1189|Stigonemataceae	1117|Cyanobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
HSJS2_k127_3550454_2	1303518.CCALI_01386	6.34e-30	122.0	COG0489@1|root,COG0489@2|Bacteria	2|Bacteria	D	protein tyrosine kinase activity	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HSJS2_k127_355352_4	590998.Celf_0512	1.587e-27	117.0	COG0346@1|root,COG0346@2|Bacteria,2IPGW@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HSJS2_k127_355352_5	1122604.JONR01000003_gene1384	1.87e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,1NIQA@1224|Proteobacteria,1SSAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HSJS2_k127_355352_7	751944.HALDL1_01735	3.922e-23	115.0	COG0477@1|root,arCOG00132@2157|Archaea,2XVCP@28890|Euryarchaeota,23UPN@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_355352_1	479434.Sthe_2035	1.536e-42	176.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HSJS2_k127_355352_6	479434.Sthe_2034	6.484e-24	107.0	COG4243@1|root,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,27YHV@189775|Thermomicrobia	189775|Thermomicrobia	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
HSJS2_k127_355352_8	1237500.ANBA01000030_gene701	5.564e-12	75.0	COG1102@1|root,COG1102@2|Bacteria,2I8J3@201174|Actinobacteria,4EJ4B@85012|Streptosporangiales	201174|Actinobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HSJS2_k127_355352_2	1347086.CCBA010000022_gene2854	2.417e-31	140.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HSJS2_k127_355352_3	1230341.MJ3_09056	8.137e-30	125.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
HSJS2_k127_355352_0	195250.CM001776_gene3771	2.424e-55	201.0	COG0730@1|root,COG0730@2|Bacteria,1GPKA@1117|Cyanobacteria,1H3F4@1129|Synechococcus	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
HSJS2_k127_3562877_0	1333998.M2A_0706	1.214e-90	308.0	COG0667@1|root,COG0667@2|Bacteria,1R7AM@1224|Proteobacteria,2U0JN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS2_k127_3562877_1	309801.trd_A0669	2.397e-87	304.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi,27Y3J@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
HSJS2_k127_3562877_2	675635.Psed_3729	3.942e-87	296.0	COG1028@1|root,COG1028@2|Bacteria,2GIVT@201174|Actinobacteria,4EAEQ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.385	ko:K19548	ko01130,map01130	M00787	R10917	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
HSJS2_k127_357120_5	1172185.KB911533_gene37	2.048e-18	91.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,4FWNP@85025|Nocardiaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_357120_2	926569.ANT_29010	5.215e-75	264.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HSJS2_k127_357120_3	309801.trd_1267	3.378e-58	220.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
HSJS2_k127_357120_0	1248760.ANFZ01000002_gene2983	8.14e-171	554.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,2K0UH@204457|Sphingomonadales	204457|Sphingomonadales	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HSJS2_k127_357120_4	1120936.KB907222_gene2318	3.866e-29	125.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria,4EJRF@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_357120_1	375286.mma_2347	2.296e-82	288.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,476TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	CoA-transferase family III	-	-	2.8.3.16,2.8.3.22	ko:K07749,ko:K14471,ko:K14472	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R00406,R03154	RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
HSJS2_k127_357120_6	1293054.HSACCH_00450	1.918e-13	73.0	COG2128@1|root,COG2128@2|Bacteria,1UVG3@1239|Firmicutes	1239|Firmicutes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HSJS2_k127_3571402_0	426114.THI_0947	8.956e-43	166.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2VR7A@28216|Betaproteobacteria,1KNN0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HSJS2_k127_3571402_3	926569.ANT_30450	1.346e-14	80.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3571402_2	357808.RoseRS_4493	8.059e-23	112.0	COG0741@1|root,COG0741@2|Bacteria	357808.RoseRS_4493|-	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3571402_4	357808.RoseRS_4494	0.0001423	54.0	COG0823@1|root,COG0823@2|Bacteria,2GB27@200795|Chloroflexi,377SI@32061|Chloroflexia	32061|Chloroflexia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3571402_1	269799.Gmet_1961	8.526e-39	159.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,43SZ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HSJS2_k127_3586600_1	1437824.BN940_11566	3.739e-90	300.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2VIMU@28216|Betaproteobacteria,3T37A@506|Alcaligenaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
HSJS2_k127_3586600_0	926560.KE387023_gene2289	4.408e-96	330.0	COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HSJS2_k127_3591145_2	1157640.AQWO01000031_gene2744	6.082e-17	93.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	strS	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HSJS2_k127_3591145_1	321327.CYA_0022	9.49e-47	183.0	COG0294@1|root,COG0294@2|Bacteria,1G050@1117|Cyanobacteria,1GZAI@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796,ko:K18824	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Pterin_bind
HSJS2_k127_3591145_0	981384.AEYW01000018_gene3160	1.312e-54	199.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,2TQXY@28211|Alphaproteobacteria,4NDRU@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS2_k127_3603995_0	479434.Sthe_1301	2.41e-267	855.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi,27XEX@189775|Thermomicrobia	189775|Thermomicrobia	L	Bacterial DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HSJS2_k127_3603995_1	518766.Rmar_2551	2.369e-113	376.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1FITR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS2_k127_3603995_2	518766.Rmar_2321	2.136e-77	269.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1FIVV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS2_k127_3603995_5	626522.GCWU000325_00300	0.000478	52.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia,1WDEE@1283313|Alloprevotella	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3603995_3	1089550.ATTH01000001_gene1008	9.449e-62	225.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1FIMW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
HSJS2_k127_3603995_4	1379698.RBG1_1C00001G1774	2.276e-34	152.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
HSJS2_k127_3611091_5	1382305.AZUC01000056_gene2115	2.994e-27	119.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,26DDK@186818|Planococcaceae	91061|Bacilli	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HSJS2_k127_3611091_3	1121272.KB903249_gene1495	8.741e-36	141.0	COG1051@1|root,COG1051@2|Bacteria,2IFB9@201174|Actinobacteria,4DETN@85008|Micromonosporales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HSJS2_k127_3611091_1	1379701.JPJC01000161_gene983	1.13e-53	196.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2K0J3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
HSJS2_k127_3611091_2	1449126.JQKL01000005_gene860	5.85e-44	174.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,268XB@186813|unclassified Clostridiales	186801|Clostridia	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HSJS2_k127_3611091_0	357808.RoseRS_1297	4.902e-126	434.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HSJS2_k127_3611091_4	479434.Sthe_1387	2.614e-32	130.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi,27XX1@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HSJS2_k127_3620434_1	867903.ThesuDRAFT_01386	2.515e-29	134.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WCXU@538999|Clostridiales incertae sedis	186801|Clostridia	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HSJS2_k127_3620434_2	439235.Dalk_4916	9.544e-11	70.0	COG1102@1|root,COG1102@2|Bacteria,1N69V@1224|Proteobacteria,42VW2@68525|delta/epsilon subdivisions,2X5RD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
HSJS2_k127_3620434_3	1122214.AQWH01000033_gene3687	2.134e-09	71.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,HemolysinCabind,Sulfatase
HSJS2_k127_3620434_0	266779.Meso_0156	5.179e-55	203.0	COG2242@1|root,COG2242@2|Bacteria,1PEB4@1224|Proteobacteria,2TXFJ@28211|Alphaproteobacteria,43NPC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3623605_0	349102.Rsph17025_0017	2.525e-47	180.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,1FAW7@1060|Rhodobacter	28211|Alphaproteobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
HSJS2_k127_3625188_8	929558.SMGD1_1332	9.636e-10	63.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2YNA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HSJS2_k127_3625188_7	710421.Mycch_1621	2.329e-18	89.0	2956B@1|root,2ZSIU@2|Bacteria,2ISPI@201174|Actinobacteria,23B2N@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3625188_9	1267533.KB906738_gene2292	2.919e-08	59.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
HSJS2_k127_3625188_2	1449126.JQKL01000009_gene344	2.723e-148	481.0	COG2059@1|root,COG2059@2|Bacteria,1TSKA@1239|Firmicutes,24EVY@186801|Clostridia,26BXE@186813|unclassified Clostridiales	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HSJS2_k127_3625188_6	1028800.RG540_PA07520	1.183e-26	121.0	COG2755@1|root,COG2755@2|Bacteria,1QM85@1224|Proteobacteria,2U34V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3625188_3	1229780.BN381_70002	5.824e-131	432.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HSJS2_k127_3625188_4	2074.JNYD01000024_gene2844	6.46e-99	352.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3625188_0	1243664.CAVL020000045_gene2115	3.137e-161	525.0	COG4799@1|root,COG4799@2|Bacteria,1VTDE@1239|Firmicutes,4HU50@91061|Bacilli,1ZFG8@1386|Bacillus	91061|Bacilli	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HSJS2_k127_3625188_1	1347369.CCAD010000043_gene993	4.39e-151	494.0	COG4799@1|root,COG4799@2|Bacteria,1VTDE@1239|Firmicutes,4HU50@91061|Bacilli,1ZFG8@1386|Bacillus	91061|Bacilli	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HSJS2_k127_3625188_5	2074.JNYD01000003_gene3804	3.904e-29	123.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DZ1Z@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3631316_5	983917.RGE_34210	9.973e-26	113.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,1KISX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HSJS2_k127_3631316_1	1480694.DC28_05120	4.649e-77	263.0	COG0180@1|root,COG0180@2|Bacteria,2J68U@203691|Spirochaetes	203691|Spirochaetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HSJS2_k127_3631316_2	1476876.JOJO01000054_gene8250	1.569e-59	224.0	COG2211@1|root,COG2211@2|Bacteria,2I3WF@201174|Actinobacteria	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_3631316_0	105559.Nwat_0489	1.4e-84	295.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1WWHU@135613|Chromatiales	135613|Chromatiales	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HSJS2_k127_3631316_3	1540221.JQNI01000002_gene2897	1.588e-36	147.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
HSJS2_k127_3639407_1	463191.SSEG_10582	9.722e-96	330.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS2_k127_3639407_0	522306.CAP2UW1_2497	2.263e-124	417.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH1N@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_3639407_2	1122135.KB893157_gene211	1.444e-57	205.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2TQQ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	dehydratase	mch	GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
HSJS2_k127_3640885_3	697284.ERIC2_c31570	1.171e-09	63.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HAAC@91061|Bacilli,275NN@186822|Paenibacillaceae	91061|Bacilli	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
HSJS2_k127_3640885_2	1133849.O3I_025710	1.96e-25	119.0	COG0030@1|root,COG0030@2|Bacteria,2H1TK@201174|Actinobacteria,4FUTS@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	-	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
HSJS2_k127_3640885_1	330084.JNYZ01000046_gene1933	7.236e-59	216.0	COG0491@1|root,COG0491@2|Bacteria,2GMSA@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase	ytnP_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_3640885_0	1123504.JQKD01000004_gene5111	1.986e-59	217.0	COG1028@1|root,COG1028@2|Bacteria,1MU3W@1224|Proteobacteria,2VMK1@28216|Betaproteobacteria,4AEM7@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_3644548_2	765123.HMPREF9621_02530	9.811e-19	90.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4DNYP@85009|Propionibacteriales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HSJS2_k127_3644548_0	68223.JNZY01000062_gene1108	7.18e-82	294.0	COG3848@1|root,COG3848@2|Bacteria,2IE61@201174|Actinobacteria	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
HSJS2_k127_3644548_1	290340.AAur_pTC20182	4.854e-42	158.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,1W96K@1268|Micrococcaceae	201174|Actinobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HSJS2_k127_3645967_3	390989.JOEG01000018_gene3684	5.847e-11	67.0	COG0477@1|root,COG2814@2|Bacteria,2GKTH@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_3645967_0	369723.Strop_3985	2.996e-36	155.0	COG0730@1|root,COG0730@2|Bacteria,2IEJQ@201174|Actinobacteria	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
HSJS2_k127_3645967_2	1128421.JAGA01000001_gene2168	1.618e-24	113.0	COG2005@1|root,COG2005@2|Bacteria,2NRCV@2323|unclassified Bacteria	2|Bacteria	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1,PBP_like_2
HSJS2_k127_3645967_1	656519.Halsa_2175	6.337e-32	128.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,3WB8W@53433|Halanaerobiales	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
HSJS2_k127_3658383_0	479434.Sthe_1230	1.184e-147	476.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
HSJS2_k127_3658383_1	479434.Sthe_1229	4.192e-67	237.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
HSJS2_k127_3661351_1	1380387.JADM01000007_gene565	9.14e-56	203.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,1S1RM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_3661351_2	981369.JQMJ01000004_gene6277	3.102e-31	133.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,2NGK5@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS2_k127_3661351_0	1205680.CAKO01000037_gene1298	2.414e-123	400.0	COG0439@1|root,COG1038@1|root,COG4799@1|root,COG0439@2|Bacteria,COG1038@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria,2JZ2C@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
HSJS2_k127_368349_1	439292.Bsel_2736	4.453e-61	219.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,26N9U@186821|Sporolactobacillaceae	91061|Bacilli	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HSJS2_k127_368349_4	1121468.AUBR01000026_gene2914	5.842e-35	143.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42EVN@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS2_k127_368349_2	1243664.CAVL020000025_gene1259	2.276e-54	199.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZMKF@1386|Bacillus	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS2_k127_368349_0	1499680.CCFE01000023_gene2582	3.172e-129	430.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4IN2H@91061|Bacilli,1ZMNA@1386|Bacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
HSJS2_k127_368349_3	646529.Desaci_2311	4.276e-36	149.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia,260K6@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
HSJS2_k127_3690363_1	331869.BAL199_24329	1.134e-127	432.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
HSJS2_k127_3690363_8	445972.ANACOL_00435	6.574e-16	85.0	COG2137@1|root,COG2137@2|Bacteria,1VJ1E@1239|Firmicutes,24QUU@186801|Clostridia,3WIJN@541000|Ruminococcaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	-	-	-	-	-	-	-	-	-	RecX
HSJS2_k127_3690363_0	1128421.JAGA01000002_gene472	1.84e-136	445.0	COG0468@1|root,COG0468@2|Bacteria,2NNYW@2323|unclassified Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HSJS2_k127_3690363_7	265729.GS18_0201935	3.614e-44	172.0	COG1670@1|root,COG1670@2|Bacteria,1UUXI@1239|Firmicutes,4I685@91061|Bacilli,1ZHU0@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HSJS2_k127_3690363_12	1470591.BW41_03019	9.865e-08	63.0	COG1872@1|root,COG1872@2|Bacteria,1NGWG@1224|Proteobacteria,2V55P@28211|Alphaproteobacteria,2K6B7@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
HSJS2_k127_3690363_9	1304888.ATWF01000001_gene735	3.315e-13	72.0	COG0762@1|root,COG0762@2|Bacteria,2GFIV@200930|Deferribacteres	200930|Deferribacteres	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
HSJS2_k127_3690363_6	383372.Rcas_1154	1.751e-49	191.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,375AU@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HSJS2_k127_3690363_4	867903.ThesuDRAFT_01649	3.086e-58	213.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WCI6@538999|Clostridiales incertae sedis	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HSJS2_k127_3690363_2	926550.CLDAP_31490	6.595e-126	427.0	COG1032@1|root,COG1032@2|Bacteria,2G7YA@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HSJS2_k127_3690363_11	1463920.JOGB01000056_gene4567	6.3e-08	60.0	COG3576@1|root,COG3576@2|Bacteria,2IKU6@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_3690363_3	994479.GL877878_gene2878	4.337e-81	281.0	COG0491@1|root,COG0491@2|Bacteria,2GMSA@201174|Actinobacteria,4E24F@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_3690363_5	1396418.BATQ01000091_gene5817	7.847e-53	201.0	COG0500@1|root,COG2226@2|Bacteria,46TDK@74201|Verrucomicrobia,2IUIX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS2_k127_3690363_10	367299.JOEE01000003_gene3069	5.035e-09	63.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4FGKF@85021|Intrasporangiaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HSJS2_k127_3696170_5	933262.AXAM01000015_gene86	5.742e-32	136.0	COG0632@1|root,COG0632@2|Bacteria,1Q5HB@1224|Proteobacteria,42R4Y@68525|delta/epsilon subdivisions,2WMRB@28221|Deltaproteobacteria,2MJPI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_N
HSJS2_k127_3696170_4	926550.CLDAP_12560	1.535e-34	138.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HSJS2_k127_3696170_3	311424.DhcVS_386	1.055e-74	259.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi,34CQY@301297|Dehalococcoidia	301297|Dehalococcoidia	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HSJS2_k127_3696170_0	1128421.JAGA01000002_gene351	1.919e-96	336.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HSJS2_k127_3696170_1	255470.cbdbA781	2.347e-93	317.0	COG0413@1|root,COG0413@2|Bacteria,2G5TQ@200795|Chloroflexi,34CNK@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HSJS2_k127_3696170_2	1111479.AXAR01000001_gene132	3.483e-84	290.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,4HD7F@91061|Bacilli,2794M@186823|Alicyclobacillaceae	91061|Bacilli	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
HSJS2_k127_3696170_7	767029.HMPREF9154_1014	3.286e-22	109.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,4DSUU@85009|Propionibacteriales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HSJS2_k127_3696170_6	1356854.N007_05870	5.829e-30	121.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,278SZ@186823|Alicyclobacillaceae	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HSJS2_k127_3700696_0	1382356.JQMP01000001_gene875	8.747e-107	356.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,27Z35@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_3702289_3	33898.JRHJ01000078_gene942	3.499e-53	192.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
HSJS2_k127_3702289_1	696369.KI912183_gene1187	2.014e-103	348.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia,2602A@186807|Peptococcaceae	186801|Clostridia	C	Dehydrogenase E1 component	pdhA	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
HSJS2_k127_3702289_5	40571.JOEA01000014_gene1833	5.311e-12	74.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4DZ0E@85010|Pseudonocardiales	201174|Actinobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
HSJS2_k127_3702289_0	1424334.W822_02615	8.271e-118	394.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2W9AM@28216|Betaproteobacteria,3T71C@506|Alcaligenaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HSJS2_k127_3702289_2	935866.JAER01000002_gene1938	8.851e-87	305.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4DPU1@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HSJS2_k127_3702289_4	935866.JAER01000002_gene1939	1.28e-14	73.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DPH5@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_370593_2	671143.DAMO_2924	4.396e-11	68.0	2CBGA@1|root,33A66@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_370593_0	521674.Plim_1852	6.94e-109	362.0	COG0614@1|root,COG0614@2|Bacteria,2IXWX@203682|Planctomycetes	203682|Planctomycetes	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HSJS2_k127_370593_1	1192034.CAP_5682	8.728e-26	112.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,42SFZ@68525|delta/epsilon subdivisions,2WPY5@28221|Deltaproteobacteria,2Z0Z7@29|Myxococcales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HSJS2_k127_3713742_2	1042163.BRLA_c001770	6.452e-25	112.0	COG2346@1|root,COG2346@2|Bacteria,1V6JN@1239|Firmicutes,4HHQG@91061|Bacilli,26YFH@186822|Paenibacillaceae	91061|Bacilli	S	Bacterial-like globin	yjbI	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HSJS2_k127_3713742_4	469383.Cwoe_2923	4.006e-10	64.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3713742_0	745014.OMB55_00013700	1.766e-42	166.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
HSJS2_k127_3713742_3	526225.Gobs_3667	2.815e-19	99.0	2DR8X@1|root,33AQM@2|Bacteria,2GXTC@201174|Actinobacteria,4EWM3@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3713742_1	1120948.KB903218_gene1718	6.925e-34	134.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria,4E7I2@85010|Pseudonocardiales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
HSJS2_k127_3731589_2	1278073.MYSTI_02931	5.739e-48	183.0	COG0697@1|root,COG0697@2|Bacteria,1Q24K@1224|Proteobacteria,437RU@68525|delta/epsilon subdivisions,2X30K@28221|Deltaproteobacteria,2Z2P4@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS2_k127_3731589_0	262316.MAP_0128c	8.497e-100	334.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,236R5@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_3731589_1	478741.JAFS01000001_gene1646	5.166e-91	315.0	COG0624@1|root,COG0624@2|Bacteria,46SJS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HSJS2_k127_3731589_3	224325.AF_1190	1.694e-42	165.0	COG1250@1|root,arCOG00250@2157|Archaea,2XTMV@28890|Euryarchaeota	28890|Euryarchaeota	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HSJS2_k127_3734138_6	1536775.H70737_17665	1.837e-05	53.0	COG3832@1|root,COG3832@2|Bacteria,1V4V8@1239|Firmicutes,4HH3Z@91061|Bacilli,26XDJ@186822|Paenibacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_3734138_3	1125863.JAFN01000001_gene2762	6.329e-15	87.0	COG0235@1|root,COG0235@2|Bacteria,1N84G@1224|Proteobacteria,42RVW@68525|delta/epsilon subdivisions,2WSI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Class II aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
HSJS2_k127_3734138_0	468556.AQYG01000047_gene1456	5.433e-74	257.0	COG1028@1|root,COG1028@2|Bacteria,2IEID@201174|Actinobacteria,4GG77@85026|Gordoniaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_3734138_1	1123023.JIAI01000007_gene1912	1.652e-69	244.0	COG1028@1|root,COG1028@2|Bacteria,2IEID@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_3734138_2	1205680.CAKO01000002_gene2488	1.528e-61	230.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_3734138_5	717605.Theco_0046	8.738e-06	57.0	COG1388@1|root,COG1388@2|Bacteria,1V2ND@1239|Firmicutes,4HGIW@91061|Bacilli,26T28@186822|Paenibacillaceae	91061|Bacilli	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	Gmad2,LysM
HSJS2_k127_3734138_4	1174528.JH992898_gene4023	1.653e-10	72.0	COG2940@1|root,COG2940@2|Bacteria,1GKRA@1117|Cyanobacteria,1JMKT@1189|Stigonemataceae	1117|Cyanobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
HSJS2_k127_3740616_5	411483.FAEPRAA2165_01592	3.837e-05	49.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3740616_2	1382356.JQMP01000003_gene1897	1.906e-44	170.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
HSJS2_k127_3740616_0	562970.Btus_0515	4.875e-166	541.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,2781B@186823|Alicyclobacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS2_k127_3740616_4	652103.Rpdx1_3362	3.043e-09	64.0	COG3620@1|root,COG3620@2|Bacteria,1N84U@1224|Proteobacteria,2TWPS@28211|Alphaproteobacteria,3JZE2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HSJS2_k127_3740616_3	797209.ZOD2009_03962	1.941e-18	96.0	COG0596@1|root,arCOG01648@2157|Archaea,2XUNG@28890|Euryarchaeota,23SVU@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	catD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
HSJS2_k127_3740616_1	1247963.JPHU01000008_gene2802	2.631e-58	231.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Mg2 and Co2 transporter CorB	corB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HSJS2_k127_3747256_1	591159.ACEZ01000099_gene5690	2.102e-63	230.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	NHL,SGL
HSJS2_k127_3747256_4	1210908.HSB1_42480	0.0004015	52.0	COG2304@1|root,arCOG07561@1|root,arCOG02902@2157|Archaea,arCOG07561@2157|Archaea,2XUQK@28890|Euryarchaeota,23TQB@183963|Halobacteria	183963|Halobacteria	K	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3747256_2	765912.Thimo_1834	1.741e-52	200.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HhH-GPD	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
HSJS2_k127_3747256_3	43759.JNWK01000001_gene5618	1.992e-20	98.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
HSJS2_k127_3747256_0	66692.ABC0006	6.056e-212	673.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HSJS2_k127_3754340_0	595460.RRSWK_01271	3.656e-54	195.0	COG1225@1|root,COG1225@2|Bacteria,2IZIQ@203682|Planctomycetes	203682|Planctomycetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS2_k127_3754340_4	679926.Mpet_2793	2.378e-12	79.0	arCOG01632@1|root,arCOG01632@2157|Archaea,2XWWZ@28890|Euryarchaeota,2NAN2@224756|Methanomicrobia	224756|Methanomicrobia	Q	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
HSJS2_k127_3754340_5	365046.Rta_20790	3.026e-08	59.0	COG3795@1|root,COG3795@2|Bacteria,1MZ5E@1224|Proteobacteria,2VWY5@28216|Betaproteobacteria,4AFP1@80864|Comamonadaceae	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS2_k127_3754340_3	1316927.ATKI01000034_gene4765	2.289e-27	128.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria,1T371@1236|Gammaproteobacteria,1YNAZ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
HSJS2_k127_3754340_1	357808.RoseRS_3952	1.815e-42	171.0	COG0477@1|root,COG0477@2|Bacteria,2GA6R@200795|Chloroflexi,3782R@32061|Chloroflexia	32061|Chloroflexia	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_3754340_6	161156.JQKW01000006_gene1143	6.807e-07	54.0	COG1522@1|root,COG1522@2|Bacteria,2GI4U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
HSJS2_k127_3754340_2	485913.Krac_6794	1.436e-27	115.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HSJS2_k127_3763574_2	398767.Glov_1385	4.486e-23	104.0	COG4276@1|root,COG4276@2|Bacteria,1N2Z3@1224|Proteobacteria,42THP@68525|delta/epsilon subdivisions,2WQJH@28221|Deltaproteobacteria,43UVI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3763574_3	945713.IALB_0032	1.08e-17	86.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
HSJS2_k127_3763574_0	1242864.D187_010288	9.764e-82	282.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
HSJS2_k127_3763574_4	404589.Anae109_3526	5.817e-15	80.0	COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,43BB8@68525|delta/epsilon subdivisions,2X6QE@28221|Deltaproteobacteria,2YVUR@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
HSJS2_k127_3763574_1	1328313.DS2_11868	2.026e-30	125.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria,46AF1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
HSJS2_k127_3765501_0	1206732.BAGD01000054_gene1961	3.239e-131	430.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_3765501_4	246194.CHY_0035	2.644e-16	89.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,42GZP@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HSJS2_k127_3765501_1	552811.Dehly_0754	3.041e-50	181.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,34DBK@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HSJS2_k127_3765501_3	525904.Tter_0780	2.309e-21	98.0	COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400	-	-	-	Ribosomal_S18
HSJS2_k127_3765501_5	479434.Sthe_1448	7.133e-05	55.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi,27XG1@189775|Thermomicrobia	189775|Thermomicrobia	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_3
HSJS2_k127_3765501_2	1392501.JIAC01000001_gene1801	1.114e-49	183.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4H2NA@909932|Negativicutes	909932|Negativicutes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
HSJS2_k127_3770296_14	936053.I1CQD8	1.018e-05	53.0	COG0028@1|root,KOG1185@2759|Eukaryota,38EFU@33154|Opisthokonta,3NU41@4751|Fungi,1GV7W@112252|Fungi incertae sedis	4751|Fungi	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	GO:0001561,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	ko:K12261	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS2_k127_3770296_10	875328.JDM601_2174	4.125e-43	168.0	COG1024@1|root,COG1024@2|Bacteria,2H2U8@201174|Actinobacteria,23AUU@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_3770296_5	247633.GP2143_12286	1.015e-68	243.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,1SZ1J@1236|Gammaproteobacteria,1JATZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_3770296_9	298655.KI912267_gene7609	3.338e-56	212.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4EUBY@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_3770296_7	314278.NB231_13791	4.797e-67	236.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1WYGC@135613|Chromatiales	135613|Chromatiales	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	-
HSJS2_k127_3770296_6	87626.PTD2_11689	1.315e-68	240.0	COG0652@1|root,COG0652@2|Bacteria,1RBX1@1224|Proteobacteria,1SYJW@1236|Gammaproteobacteria,2Q28R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HSJS2_k127_3770296_3	518766.Rmar_1742	1.154e-70	250.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1FJG8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HSJS2_k127_3770296_8	279714.FuraDRAFT_3510	9.506e-66	242.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2VUT6@28216|Betaproteobacteria,2KTQX@206351|Neisseriales	206351|Neisseriales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HSJS2_k127_3770296_4	767817.Desgi_3217	1.945e-69	246.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,25EG6@186801|Clostridia,265GT@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_3770296_11	29306.JOBE01000024_gene307	5.361e-33	135.0	COG0125@1|root,COG0125@2|Bacteria,2I3EK@201174|Actinobacteria	201174|Actinobacteria	F	Chloramphenicol phosphotransferase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,CPT
HSJS2_k127_3770296_0	1160137.KB907308_gene7463	5.437e-134	449.0	28JZQ@1|root,2Z9PN@2|Bacteria,2I9HT@201174|Actinobacteria,4G6HD@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3770296_1	953739.SVEN_0524	1.529e-99	337.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS2_k127_3770296_12	235985.BBPN01000017_gene5677	1.067e-23	107.0	COG0789@1|root,COG0789@2|Bacteria,2IC98@201174|Actinobacteria,2NGH2@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HSJS2_k127_3770296_2	1122614.JHZF01000014_gene2718	1.906e-90	307.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria	1224|Proteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS2_k127_3774313_3	2074.JNYD01000001_gene5857	2.285e-16	89.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,4E60J@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
HSJS2_k127_3774313_2	1128421.JAGA01000002_gene1930	2.411e-60	226.0	COG0111@1|root,COG0111@2|Bacteria,2NQUW@2323|unclassified Bacteria	2|Bacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS2_k127_3774313_1	525904.Tter_2256	5.39e-194	630.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2NQQF@2323|unclassified Bacteria	2|Bacteria	C	LUD domain	lutB	-	-	ko:K00782,ko:K18929	-	-	-	-	ko00000	-	-	-	CCG,DUF3390,Fer4_8,LUD_dom
HSJS2_k127_3774313_4	1382306.JNIM01000001_gene2927	8.647e-14	83.0	COG1556@1|root,COG1556@2|Bacteria	2|Bacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
HSJS2_k127_3774313_0	1038859.AXAU01000003_gene6016	0.0	1118.0	COG0439@1|root,COG4770@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria,3JUPC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Biotin carboxylase C-terminal domain	MA20_04765	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
HSJS2_k127_3774475_0	382464.ABSI01000013_gene1799	2.344e-89	314.0	COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,2IU82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Divalent cation transporter	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
HSJS2_k127_3774475_1	390235.PputW619_2292	6.97e-23	110.0	COG2267@1|root,COG2267@2|Bacteria,1PFKT@1224|Proteobacteria,1TKK5@1236|Gammaproteobacteria,1YWZ3@136845|Pseudomonas putida group	1236|Gammaproteobacteria	I	PFAM Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_3774475_2	1121090.KB894689_gene409	1.369e-17	85.0	COG1853@1|root,COG1853@2|Bacteria,1V7DF@1239|Firmicutes,4HISF@91061|Bacilli,1ZFPB@1386|Bacillus	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HSJS2_k127_3779497_4	330214.NIDE0852	9.256e-08	58.0	COG0644@1|root,COG0644@2|Bacteria,3J0UE@40117|Nitrospirae	40117|Nitrospirae	C	oxidoreductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
HSJS2_k127_3779497_2	768671.ThimaDRAFT_4622	1.044e-50	202.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria,1X0YI@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS2_k127_3779497_3	1463853.JOHW01000004_gene2393	1.024e-23	104.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
HSJS2_k127_3779497_0	311424.DhcVS_737	1.23e-211	673.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,34CWN@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS2_k127_3779497_1	264732.Moth_2257	6.981e-55	199.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,42GAW@68295|Thermoanaerobacterales	186801|Clostridia	E	Acetolactate synthase, small subunit	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
HSJS2_k127_3811422_2	1343740.M271_45150	7.243e-31	126.0	COG1359@1|root,COG1359@2|Bacteria,2I72N@201174|Actinobacteria	201174|Actinobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
HSJS2_k127_3811422_4	756883.Halar_1291	5.207e-14	78.0	arCOG09395@1|root,arCOG09395@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS2_k127_3811422_1	1197130.BAFM01000006_gene1198	4.142e-44	169.0	arCOG09395@1|root,arCOG09395@2157|Archaea,2XTUR@28890|Euryarchaeota,23S6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS2_k127_3811422_0	1342301.JASD01000008_gene2693	1.197e-189	606.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,3ZWPH@60136|Sulfitobacter	28211|Alphaproteobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS2_k127_3811422_3	1342302.JASC01000013_gene2938	1.726e-28	117.0	2E6FA@1|root,3312Q@2|Bacteria,1NCPQ@1224|Proteobacteria,2UKWD@28211|Alphaproteobacteria,3ZXTE@60136|Sulfitobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3858206_4	479434.Sthe_0078	9.697e-24	106.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_3858206_1	1313172.YM304_11160	3.227e-60	224.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CCP_MauG,Copper-bind,Cu-oxidase_3,Cupredoxin_1
HSJS2_k127_3858206_3	1128421.JAGA01000002_gene1937	4.284e-30	136.0	COG0477@1|root,COG2814@2|Bacteria,2NS3M@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_3858206_0	1133849.O3I_017965	3.32e-71	251.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4FZ9I@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
HSJS2_k127_3858206_2	2074.JNYD01000001_gene6177	2.422e-51	194.0	COG1960@1|root,COG1960@2|Bacteria,2H7DI@201174|Actinobacteria,4DZXM@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_3860404_0	502025.Hoch_4973	8.577e-162	519.0	COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2YUE6@29|Myxococcales	28221|Deltaproteobacteria	L	Deoxyribodipyrimidine photo-lyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
HSJS2_k127_3860404_1	926569.ANT_25430	7.871e-72	255.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HSJS2_k127_3860404_2	1032480.MLP_17740	2.237e-14	76.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2I8T8@201174|Actinobacteria,4DS8V@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
HSJS2_k127_3861151_4	324602.Caur_2578	2.018e-49	180.0	COG2038@1|root,COG2038@2|Bacteria,2G5R3@200795|Chloroflexi,376BT@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
HSJS2_k127_3861151_8	42256.RradSPS_0826	1.006e-30	132.0	COG0368@1|root,COG0368@2|Bacteria,2HP52@201174|Actinobacteria,4CQGW@84995|Rubrobacteria	84995|Rubrobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
HSJS2_k127_3861151_3	693977.Deipr_2602	1.713e-50	184.0	COG2087@1|root,COG2087@2|Bacteria,1WMP8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
HSJS2_k127_3861151_2	1118060.CAGZ01000012_gene41	3.346e-59	222.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CV2A@84998|Coriobacteriia	84998|Coriobacteriia	O	PDZ DHR GLGF domain protein	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
HSJS2_k127_3861151_1	1217718.ALOU01000047_gene3762	6.832e-67	246.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2VJSH@28216|Betaproteobacteria,1KGDI@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	echA8_4	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS2_k127_3861151_6	1394178.AWOO02000006_gene3291	2.479e-45	182.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4EH92@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_3861151_7	1137269.AZWL01000001_gene5347	3.342e-41	159.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_3861151_9	1121380.JNIW01000071_gene3552	1.741e-07	64.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K04772,ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FHA,Trypsin_2
HSJS2_k127_3861151_0	1382356.JQMP01000003_gene2203	6.561e-87	302.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi,27XYI@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS2_k127_3861151_5	926550.CLDAP_22950	6.232e-48	179.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
HSJS2_k127_3869733_1	1121930.AQXG01000001_gene1415	1.503e-15	83.0	COG0749@1|root,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HSJS2_k127_3869733_0	479434.Sthe_0322	1.107e-100	341.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia	189775|Thermomicrobia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HSJS2_k127_3885923_1	762966.HMPREF9439_00692	2.981e-10	64.0	COG0044@1|root,COG0044@2|Bacteria,1PXW5@1224|Proteobacteria,2W04P@28216|Betaproteobacteria,4PQVF@995019|Sutterellaceae	28216|Betaproteobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS2_k127_3885923_2	1487923.DP73_09300	3.135e-07	63.0	COG4655@1|root,COG4655@2|Bacteria,1V25X@1239|Firmicutes,24GGW@186801|Clostridia,267CD@186807|Peptococcaceae	186801|Clostridia	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
HSJS2_k127_3885923_0	1244869.H261_02431	2.098e-94	326.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TT4A@28211|Alphaproteobacteria,2JRFR@204441|Rhodospirillales	204441|Rhodospirillales	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3886659_1	1340493.JNIF01000003_gene2232	7.64e-102	343.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HSJS2_k127_3886659_2	656024.FsymDg_2568	2.45e-62	231.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4ET2V@85013|Frankiales	201174|Actinobacteria	Q	PFAM isochorismatase hydrolase	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
HSJS2_k127_3886659_0	246197.MXAN_7166	9.702e-114	381.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2YU8U@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
HSJS2_k127_3891861_6	1121365.AQXB01000001_gene978	1.056e-10	71.0	2AU69@1|root,31JT7@2|Bacteria,2IFP7@201174|Actinobacteria,22P0H@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3891861_3	861299.J421_0662	7.773e-40	153.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS2_k127_3891861_4	977880.RALTA_A0472	7.204e-26	121.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2VNEM@28216|Betaproteobacteria,1K5AJ@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS2_k127_3891861_7	1385510.N781_07005	4.169e-07	60.0	COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,4HHXX@91061|Bacilli,2Y8U6@289201|Pontibacillus	91061|Bacilli	S	Alkaline phosphatase	ytxB	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HSJS2_k127_3891861_2	58123.JOFJ01000014_gene4980	1.583e-63	243.0	COG1028@1|root,COG1028@2|Bacteria,2IEID@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_3891861_0	1429916.X566_06480	3.885e-153	493.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TT8C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_3891861_1	298655.KI912266_gene5821	1.121e-66	237.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_3891861_5	1248917.ANFX01000019_gene2321	1.181e-12	74.0	COG3828@1|root,COG3828@2|Bacteria,1QWCA@1224|Proteobacteria,2U1GQ@28211|Alphaproteobacteria,2K19I@204457|Sphingomonadales	204457|Sphingomonadales	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
HSJS2_k127_3896393_1	357808.RoseRS_2190	1.034e-15	87.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
HSJS2_k127_3896393_0	926550.CLDAP_29080	6.196e-137	465.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
HSJS2_k127_3896393_2	215803.DB30_6557	1.947e-09	70.0	COG1520@1|root,COG3055@1|root,COG4676@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,COG4676@2|Bacteria,1NZI5@1224|Proteobacteria,43AH4@68525|delta/epsilon subdivisions,2X5X4@28221|Deltaproteobacteria,2Z37E@29|Myxococcales	1224|Proteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1,Kelch_4,PKD,UPF0560
HSJS2_k127_3900263_3	864702.OsccyDRAFT_1898	7.369e-11	67.0	COG2944@1|root,COG2944@2|Bacteria,1G6V7@1117|Cyanobacteria,1HBR9@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HSJS2_k127_3900263_2	31964.CMS0526	6.579e-24	105.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4FP1U@85023|Microbacteriaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HSJS2_k127_3900263_0	309801.trd_1300	1.744e-200	637.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,27Y1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HSJS2_k127_3900263_1	552811.Dehly_1402	5.596e-32	131.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,34CMZ@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS2_k127_390071_0	1380390.JIAT01000010_gene4861	5.722e-23	106.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4CQN1@84995|Rubrobacteria	84995|Rubrobacteria	M	Large-conductance mechanosensitive channel, MscL	-	-	-	-	-	-	-	-	-	-	-	-	MscL
HSJS2_k127_390071_1	525904.Tter_1026	0.0004207	45.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
HSJS2_k127_3903982_4	1224163.B841_09440	1.843e-11	69.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria,22RMV@1653|Corynebacteriaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_3903982_2	649831.L083_3664	8.026e-46	178.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	yflN	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_3903982_0	439235.Dalk_1981	2.388e-91	319.0	COG1028@1|root,COG1028@2|Bacteria,1MXNY@1224|Proteobacteria,43AI2@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K18335	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10690,R11671	RC00029,RC00089,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_3909174_0	479434.Sthe_2325	2.048e-72	255.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HSJS2_k127_3909174_3	1968.JOEV01000045_gene2277	3.476e-16	93.0	2BWWR@1|root,2ZG0F@2|Bacteria,2GXC8@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3909174_2	318996.AXAZ01000001_gene4814	8.888e-38	149.0	COG1247@1|root,COG1247@2|Bacteria,1R6UW@1224|Proteobacteria,2U09H@28211|Alphaproteobacteria,3JQVX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_3909174_1	595537.Varpa_5318	3.675e-41	161.0	COG1247@1|root,COG1247@2|Bacteria,1R6UW@1224|Proteobacteria,2W2QC@28216|Betaproteobacteria,4AHQC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_3909174_4	298653.Franean1_0517	5.898e-07	53.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_3921818_5	1333523.L593_09185	1.482e-14	85.0	arCOG10180@1|root,arCOG10180@2157|Archaea,2XUY5@28890|Euryarchaeota,23U72@183963|Halobacteria	183963|Halobacteria	S	membrane-bound metal-dependent	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
HSJS2_k127_3921818_6	1530186.JQEY01000022_gene506	3.511e-10	69.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
HSJS2_k127_3921818_1	1463864.JOGO01000033_gene1489	2.018e-42	175.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp20	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
HSJS2_k127_3921818_3	585530.HMPREF0183_1990	6.133e-20	96.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
HSJS2_k127_3921818_2	204773.HEAR1712	3.459e-30	125.0	COG2461@1|root,COG2461@2|Bacteria,1QX14@1224|Proteobacteria,2WH3M@28216|Betaproteobacteria,478DM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS
HSJS2_k127_3921818_4	1193181.BN10_540010	1.377e-18	86.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,4FF8K@85021|Intrasporangiaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HSJS2_k127_3923560_2	525368.HMPREF0591_0025	9.684e-07	56.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria,23B3Y@1762|Mycobacteriaceae	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3923560_3	1121015.N789_11125	7.738e-05	50.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1X86G@135614|Xanthomonadales	135614|Xanthomonadales	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
HSJS2_k127_3923560_1	525368.HMPREF0591_0024	3.607e-16	85.0	2BZG6@1|root,2ZH9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3923560_0	882083.SacmaDRAFT_2041	4.109e-98	350.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EAD8@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_3945798_0	926550.CLDAP_27640	1.153e-67	239.0	COG0745@1|root,COG0745@2|Bacteria,2G8CC@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_3945798_4	580327.Tthe_2191	5.474e-08	59.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia,42HB6@68295|Thermoanaerobacterales	186801|Clostridia	T	Carbon storage regulator	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
HSJS2_k127_3945798_2	479434.Sthe_0569	3.424e-57	210.0	COG1191@1|root,COG1191@2|Bacteria,2G8JZ@200795|Chloroflexi,27Y01@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS2_k127_3945798_3	264198.Reut_B5599	1.346e-15	87.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSDT@28216|Betaproteobacteria,1KH7T@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	cheY2	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
HSJS2_k127_3945798_1	1382306.JNIM01000001_gene1045	4.076e-59	215.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_3984538_0	391625.PPSIR1_29725	9.393e-178	563.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YU3W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
HSJS2_k127_3984538_2	266117.Rxyl_0279	2.899e-58	214.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CQ8R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HSJS2_k127_3984538_6	1206720.BAFQ01000066_gene1798	1.866e-15	89.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4FXKE@85025|Nocardiaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
HSJS2_k127_3984538_1	316274.Haur_4439	9.689e-127	415.0	COG0473@1|root,COG0473@2|Bacteria,2G63C@200795|Chloroflexi,3755M@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HSJS2_k127_3984538_3	1120950.KB892831_gene5056	2.203e-44	175.0	COG3173@1|root,COG3173@2|Bacteria,2H16C@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.163	ko:K18817	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
HSJS2_k127_3984538_5	1123322.KB904735_gene1470	2.486e-19	101.0	COG1051@1|root,COG1051@2|Bacteria,2INBQ@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HSJS2_k127_3984538_4	765420.OSCT_0356	2.305e-40	155.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi,3758Q@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
HSJS2_k127_3985828_0	316274.Haur_0244	5.209e-148	480.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi,374ZB@32061|Chloroflexia	32061|Chloroflexia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HSJS2_k127_3985828_1	1090320.KB900605_gene3394	7.97e-11	71.0	COG2940@1|root,COG2940@2|Bacteria,1Q9DE@1224|Proteobacteria,2VDKT@28211|Alphaproteobacteria,2K32C@204457|Sphingomonadales	204457|Sphingomonadales	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HSJS2_k127_3989390_0	1173022.Cri9333_4368	6.85e-17	87.0	COG1943@1|root,COG1943@2|Bacteria,1G603@1117|Cyanobacteria,1HC8N@1150|Oscillatoriales	1117|Cyanobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
HSJS2_k127_3993045_2	439235.Dalk_3095	8.862e-20	89.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HSJS2_k127_3993045_3	1120956.JHZK01000017_gene2664	2.863e-09	65.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VCGZ@28211|Alphaproteobacteria,1JPIV@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
HSJS2_k127_3993045_0	479434.Sthe_0100	2.988e-98	332.0	COG2141@1|root,COG2141@2|Bacteria,2GB6V@200795|Chloroflexi,27XHN@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_3993045_1	234267.Acid_5780	2.027e-45	174.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
HSJS2_k127_3994376_3	426368.MmarC7_1110	0.0005947	49.0	arCOG06590@1|root,arCOG06590@2157|Archaea,2XXEI@28890|Euryarchaeota,23QWZ@183939|Methanococci	183939|Methanococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_3994376_0	243164.DET0845	1.231e-85	302.0	COG0040@1|root,COG0040@2|Bacteria,2G6DD@200795|Chloroflexi,34CWY@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
HSJS2_k127_3994376_1	243164.DET0846	8.707e-62	229.0	COG0124@1|root,COG0124@2|Bacteria,2G962@200795|Chloroflexi,34CX8@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
HSJS2_k127_3994376_2	644966.Tmar_1289	1.105e-35	147.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WCNE@538999|Clostridiales incertae sedis	186801|Clostridia	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HSJS2_k127_3998428_1	1380393.JHVP01000003_gene1268	4.121e-129	424.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
HSJS2_k127_3998428_3	526225.Gobs_3758	2.055e-69	247.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria,4EX7F@85013|Frankiales	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HSJS2_k127_3998428_0	1298867.AUES01000038_gene864	1.109e-217	692.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQU2@28211|Alphaproteobacteria,3JS7A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
HSJS2_k127_3998428_2	880073.Calab_1751	2.778e-93	314.0	COG3264@1|root,COG3264@2|Bacteria,2NPZR@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	kefA	-	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel
HSJS2_k127_3998428_4	670487.Ocepr_1976	6.691e-66	229.0	COG0174@1|root,COG0174@2|Bacteria,1WM8G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
HSJS2_k127_4008703_7	335541.Swol_0468	5.044e-11	64.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,42JKC@68298|Syntrophomonadaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HSJS2_k127_4008703_6	1336208.JADY01000008_gene2100	1.24e-15	89.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,2JSP7@204441|Rhodospirillales	204441|Rhodospirillales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HSJS2_k127_4008703_4	926550.CLDAP_39240	2.706e-54	205.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HSJS2_k127_4008703_3	1382356.JQMP01000001_gene1048	2.315e-59	215.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi,27XST@189775|Thermomicrobia	189775|Thermomicrobia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HSJS2_k127_4008703_1	525904.Tter_0109	4.284e-118	395.0	COG0082@1|root,COG0082@2|Bacteria,2NNQ8@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976,iNJ661.Rv2540c	Chorismate_synt
HSJS2_k127_4008703_0	1382306.JNIM01000001_gene1342	3.055e-122	413.0	COG0337@1|root,COG0337@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
HSJS2_k127_4008703_5	670487.Ocepr_0936	2.87e-19	97.0	COG1254@1|root,COG1254@2|Bacteria,1WK7T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
HSJS2_k127_4008703_8	395963.Bind_1966	1.679e-07	64.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,3NB49@45404|Beijerinckiaceae	28211|Alphaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
HSJS2_k127_4008703_2	525904.Tter_1452	1.217e-78	271.0	COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria	2|Bacteria	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HSJS2_k127_400996_2	711393.AYRX01000086_gene5239	1.406e-06	57.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria	201174|Actinobacteria	K	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
HSJS2_k127_400996_1	1299327.I546_4511	1.541e-29	127.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,23BEX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS2_k127_4020086_0	552811.Dehly_0932	1.158e-141	460.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi,34CSW@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HSJS2_k127_4020086_1	243164.DET1258	9.068e-124	416.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi,34D4B@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS2_k127_4020086_2	1128427.KB904821_gene4030	2.279e-98	330.0	COG1615@1|root,COG1615@2|Bacteria,1G05D@1117|Cyanobacteria,1H8E1@1150|Oscillatoriales	1117|Cyanobacteria	S	UPF0182 protein	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
HSJS2_k127_4022889_1	1292034.OR37_02704	2.514e-70	241.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2U14P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS2_k127_4022889_0	926566.Terro_4363	1.632e-102	341.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
HSJS2_k127_4022889_3	266117.Rxyl_1184	3.027e-16	84.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
HSJS2_k127_4022889_2	211114.JOEF01000020_gene785	1.025e-37	161.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4E2DC@85010|Pseudonocardiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
HSJS2_k127_4022889_4	362242.MUL_2265	5.945e-06	49.0	COG0451@1|root,COG3848@1|root,COG0451@2|Bacteria,COG3848@2|Bacteria,2H2J1@201174|Actinobacteria,232PK@1762|Mycobacteriaceae	201174|Actinobacteria	GMT	PEP-utilising enzyme, mobile domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Epimerase,PEP-utilizers
HSJS2_k127_4030431_3	864069.MicloDRAFT_00051340	9.115e-47	179.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,1JTCM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_4030431_5	1105367.CG50_12735	7.275e-12	78.0	COG1011@1|root,COG1011@2|Bacteria,1RHAB@1224|Proteobacteria,2U7PV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolase (HAD superfamily)	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
HSJS2_k127_4030431_2	1146883.BLASA_1289	4.04e-54	211.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4EXI6@85013|Frankiales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
HSJS2_k127_4030431_0	1117379.BABA_03844	5.736e-185	593.0	COG4799@1|root,COG4799@2|Bacteria,1VTDE@1239|Firmicutes,4HU50@91061|Bacilli,1ZFG8@1386|Bacillus	91061|Bacilli	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HSJS2_k127_4030431_6	631454.N177_1475	2.553e-09	63.0	COG4770@1|root,COG4770@2|Bacteria,1PU81@1224|Proteobacteria,2VCYP@28211|Alphaproteobacteria,1JQK3@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
HSJS2_k127_4030431_4	1123239.KB898625_gene340	1.984e-34	139.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli	91061|Bacilli	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS2_k127_4030431_1	324602.Caur_0549	9.562e-55	198.0	COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS2_k127_4037725_1	585531.HMPREF0063_10436	1.501e-64	230.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4DN46@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_4037725_2	101510.RHA1_ro00049	5.386e-50	198.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4FV4F@85025|Nocardiaceae	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	devS	-	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA_3
HSJS2_k127_4037725_0	1206731.BAGB01000054_gene3893	3.546e-99	344.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
HSJS2_k127_4037725_3	1499967.BAYZ01000139_gene119	3.219e-22	102.0	COG0346@1|root,COG0346@2|Bacteria,2NPRH@2323|unclassified Bacteria	2|Bacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HSJS2_k127_4065875_1	331869.BAL199_27206	1.109e-86	296.0	COG0412@1|root,COG0412@2|Bacteria,1R9JT@1224|Proteobacteria,2U4J1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
HSJS2_k127_4065875_2	1306990.BARG01000086_gene8534	6.204e-17	93.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_4065875_4	247633.GP2143_02804	9.311e-09	66.0	COG2030@1|root,COG2030@2|Bacteria,1NYEM@1224|Proteobacteria	1224|Proteobacteria	I	dehydratase	MA20_27475	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_4065875_5	1429046.RR21198_4974	2.33e-06	58.0	COG4689@1|root,COG4689@2|Bacteria	2|Bacteria	Q	acetoacetate decarboxylase activity	adc	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
HSJS2_k127_4065875_3	1112204.GPOL_c29660	2.929e-13	80.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4GAKX@85026|Gordoniaceae	201174|Actinobacteria	S	Uncharacterised protein, DegV family COG1307	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DegV
HSJS2_k127_4065875_0	1205680.CAKO01000035_gene257	2.116e-112	375.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TV8M@28211|Alphaproteobacteria,2JXBR@204441|Rhodospirillales	204441|Rhodospirillales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_4067839_1	448385.sce8911	9.657e-69	238.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS2_k127_4067839_3	1121033.AUCF01000008_gene5747	1.137e-49	183.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,2TW76@28211|Alphaproteobacteria,2JT9T@204441|Rhodospirillales	204441|Rhodospirillales	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HSJS2_k127_4067839_0	937777.Deipe_0108	5.873e-240	766.0	COG1331@1|root,COG1331@2|Bacteria,1WI7F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HSJS2_k127_4067839_2	227086.JGI_V11_86592	1.426e-54	208.0	COG0477@1|root,2T0TA@2759|Eukaryota	2759|Eukaryota	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_4070716_1	1248916.ANFY01000011_gene1083	7.202e-52	186.0	COG0251@1|root,COG0251@2|Bacteria,1RDFC@1224|Proteobacteria,2U8PR@28211|Alphaproteobacteria,2K6NW@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HSJS2_k127_4070716_0	234267.Acid_5780	1.059e-91	317.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
HSJS2_k127_4073675_0	509190.Cseg_2255	1.833e-123	414.0	COG0183@1|root,COG0183@2|Bacteria,1MVPC@1224|Proteobacteria,2VEVD@28211|Alphaproteobacteria,2KF3X@204458|Caulobacterales	204458|Caulobacterales	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
HSJS2_k127_4074789_0	1161401.ASJA01000006_gene2008	1.54e-12	76.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2TTN7@28211|Alphaproteobacteria,43XM8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	phosphoribosyltransferase	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HSJS2_k127_4074789_1	1150621.SMUL_2745	7.644e-08	64.0	COG1102@1|root,COG1102@2|Bacteria,1N69V@1224|Proteobacteria,42VW2@68525|delta/epsilon subdivisions,2YQM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HSJS2_k127_4074789_2	1033730.CAHG01000014_gene1573	2.731e-05	55.0	COG3087@1|root,COG3087@2|Bacteria,2GNX9@201174|Actinobacteria,4DQMG@85009|Propionibacteriales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_4086734_3	930171.Asphe3_09460	1.515e-20	102.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_4086734_1	1463895.JODA01000046_gene2011	2.932e-23	107.0	COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_4086734_2	43759.JNWK01000016_gene259	4.936e-22	101.0	COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_4086734_4	1123248.KB893327_gene770	1.536e-13	76.0	COG3832@1|root,COG3832@2|Bacteria,4NQXU@976|Bacteroidetes,1IXTD@117747|Sphingobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_4086734_0	749927.AMED_4721	5.635e-24	113.0	COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria,4E7G8@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_4104838_3	1089549.AZUQ01000001_gene1585	7.114e-14	78.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4EYMK@85014|Glycomycetales	201174|Actinobacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HSJS2_k127_4104838_2	749414.SBI_06014	2.041e-84	293.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HSJS2_k127_4104838_0	1089544.KB912942_gene4161	9.086e-147	495.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_4104838_1	113395.AXAI01000002_gene5237	6.245e-143	460.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,2VF18@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_412990_1	485913.Krac_8372	9.913e-19	100.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
HSJS2_k127_412990_0	926569.ANT_16650	5.296e-108	357.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HSJS2_k127_421365_4	1206732.BAGD01000054_gene1961	2.949e-72	257.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_421365_2	1246626.BleG1_0541	1.666e-118	396.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli,1ZE8W@1386|Bacillus	91061|Bacilli	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS2_k127_421365_1	479434.Sthe_0784	2.79e-131	432.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi,27Y4R@189775|Thermomicrobia	189775|Thermomicrobia	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS2_k127_421365_3	1382356.JQMP01000004_gene319	3.44e-112	379.0	COG3653@1|root,COG3653@2|Bacteria,2G86A@200795|Chloroflexi,27ZD5@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HSJS2_k127_421365_5	1206101.AZXC01000001_gene4560	4.013e-42	173.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
HSJS2_k127_421365_6	1382306.JNIM01000001_gene3012	1.318e-33	147.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_421365_0	1382306.JNIM01000001_gene3014	4.069e-137	446.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HSJS2_k127_425338_3	378806.STAUR_4942	0.0001958	47.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	NHL,SGL
HSJS2_k127_425338_0	795359.TOPB45_1257	2.945e-170	547.0	COG0174@1|root,COG0174@2|Bacteria,2GH5N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HSJS2_k127_425338_1	105420.BBPO01000014_gene6045	1.689e-27	116.0	COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria,2NIUF@228398|Streptacidiphilus	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS2_k127_425338_2	385682.AFSL01000035_gene2913	1.563e-26	115.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,2FNEC@200643|Bacteroidia,3XJJF@558415|Marinilabiliaceae	976|Bacteroidetes	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HSJS2_k127_447123_0	1348657.M622_02910	6.321e-59	214.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	ygcR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HSJS2_k127_447123_2	644966.Tmar_0477	1.81e-47	185.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WCFX@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HSJS2_k127_447123_4	439235.Dalk_4877	1.256e-28	124.0	COG0613@1|root,COG0613@2|Bacteria,1NFVB@1224|Proteobacteria,43BBY@68525|delta/epsilon subdivisions,2X6R1@28221|Deltaproteobacteria,2MPIB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	APH,DUF2889,PHP_C
HSJS2_k127_447123_3	1040989.AWZU01000011_gene4018	6.497e-47	183.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,3JTHE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	MA20_35840	-	1.1.1.264	ko:K00098	-	-	R05684	RC00089	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS2_k127_447123_1	1120948.KB903229_gene5150	1.068e-55	203.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4E0A8@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
HSJS2_k127_450329_0	1120973.AQXL01000123_gene3026	9.036e-92	313.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,277V7@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HSJS2_k127_450329_2	485913.Krac_9969	4.854e-52	199.0	COG0548@1|root,COG0548@2|Bacteria,2G6ZG@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HSJS2_k127_450329_1	381666.H16_A1615	3.111e-88	309.0	COG1615@1|root,COG1615@2|Bacteria,1MZ5A@1224|Proteobacteria,2W1FV@28216|Betaproteobacteria,1K502@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
HSJS2_k127_45795_4	309801.trd_A0504	4.219e-08	60.0	COG0630@1|root,COG0630@2|Bacteria,2G943@200795|Chloroflexi,27YBM@189775|Thermomicrobia	189775|Thermomicrobia	NU	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_45795_6	1532557.JL37_20240	3.361e-05	54.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,2VRMX@28216|Betaproteobacteria,3T3SK@506|Alcaligenaceae	28216|Betaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_45795_0	1382356.JQMP01000004_gene366	0.0	1193.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
HSJS2_k127_45795_3	1224163.B841_05230	1.437e-28	117.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,22N7C@1653|Corynebacteriaceae	201174|Actinobacteria	C	ferredoxin	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fer4
HSJS2_k127_45795_5	266835.14022619	4.234e-06	51.0	COG2206@1|root,COG2771@1|root,COG2206@2|Bacteria,COG2771@2|Bacteria,1QUHF@1224|Proteobacteria,2U2XM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
HSJS2_k127_45795_2	1120949.KB903357_gene5007	1.183e-33	145.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HSJS2_k127_45795_1	1121353.H924_09580	1.169e-46	171.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,22KFN@1653|Corynebacteriaceae	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
HSJS2_k127_4581_2	1382356.JQMP01000004_gene351	3.874e-55	199.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,27Y20@189775|Thermomicrobia	189775|Thermomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HSJS2_k127_4581_3	237368.SCABRO_02834	1.657e-21	103.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS2_k127_4581_1	1157943.KB892705_gene4012	1.244e-63	222.0	COG3871@1|root,COG3871@2|Bacteria,2IFC3@201174|Actinobacteria,238T2@1762|Mycobacteriaceae	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HSJS2_k127_4581_0	1463934.JOCF01000079_gene6602	2.444e-66	235.0	COG0596@1|root,COG0596@2|Bacteria,2IACG@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
HSJS2_k127_458925_2	1232429.CBLL010000136_gene1206	5.408e-97	330.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,1W82Y@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS2_k127_458925_1	760568.Desku_1351	8.656e-111	373.0	COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,24BFZ@186801|Clostridia,260NH@186807|Peptococcaceae	186801|Clostridia	S	PFAM MmgE PrpD	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
HSJS2_k127_458925_0	479434.Sthe_2669	1.352e-166	545.0	COG1067@1|root,COG1067@2|Bacteria,2G64R@200795|Chloroflexi,27XSI@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
HSJS2_k127_472962_0	1121396.KB892935_gene3861	1.954e-47	194.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_472962_1	1288298.rosmuc_03541	6.856e-20	91.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,46PEX@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HSJS2_k127_48190_1	479434.Sthe_1582	1.029e-88	305.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
HSJS2_k127_48190_0	479434.Sthe_1583	2.532e-240	756.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,27XSC@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HSJS2_k127_48190_2	1379270.AUXF01000002_gene1827	1.964e-53	196.0	COG1845@1|root,COG1845@2|Bacteria,1ZT8Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
HSJS2_k127_497236_1	324602.Caur_3417	6.612e-46	175.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi,375NQ@32061|Chloroflexia	32061|Chloroflexia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HSJS2_k127_497236_5	1111732.AZOD01000005_gene837	1.632e-06	57.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria	1224|Proteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HSJS2_k127_497236_4	552811.Dehly_0305	1.228e-22	104.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi,34DGE@301297|Dehalococcoidia	301297|Dehalococcoidia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HSJS2_k127_497236_2	1382356.JQMP01000003_gene1311	1.845e-31	128.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi,27YFI@189775|Thermomicrobia	189775|Thermomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HSJS2_k127_497236_0	326427.Cagg_0281	2.073e-75	267.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,3759E@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_497236_3	1131730.BAVI_20199	7.38e-27	114.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HSJS2_k127_505218_7	1519464.HY22_11880	0.0001088	45.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS2_k127_505218_4	684949.ATTJ01000001_gene2105	2.086e-25	122.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HSJS2_k127_505218_2	1110502.TMO_3297	2.444e-66	235.0	COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,2TV4E@28211|Alphaproteobacteria,2JWBD@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_505218_0	485913.Krac_10287	5.258e-153	499.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
HSJS2_k127_505218_3	324602.Caur_1144	3.218e-50	199.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
HSJS2_k127_505218_1	562970.Btus_2619	1.138e-105	357.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,278U1@186823|Alicyclobacillaceae	91061|Bacilli	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
HSJS2_k127_505218_5	1122128.AUEE01000002_gene1092	1.898e-24	110.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,4GZFP@90964|Staphylococcaceae	91061|Bacilli	S	Iron-sulfur cluster assembly protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
HSJS2_k127_505218_6	1158609.I586_01843	2.32e-19	91.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,4B2CY@81852|Enterococcaceae	91061|Bacilli	C	NifU-like N terminal domain	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HSJS2_k127_521537_2	1122614.JHZF01000001_gene357	6.512e-73	257.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,2PENX@252301|Oceanicola	28211|Alphaproteobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HSJS2_k127_521537_1	1089544.KB912942_gene2678	1.438e-107	355.0	COG3959@1|root,COG3959@2|Bacteria,2GJ6M@201174|Actinobacteria,4DYR6@85010|Pseudonocardiales	201174|Actinobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HSJS2_k127_521537_4	1077974.GOEFS_015_00560	5.024e-11	73.0	COG1309@1|root,COG1309@2|Bacteria,2GP59@201174|Actinobacteria,4GFWK@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
HSJS2_k127_521537_0	1122611.KB903945_gene1394	2.961e-130	428.0	COG0001@1|root,COG0001@2|Bacteria,2GKJV@201174|Actinobacteria,4EI3K@85012|Streptosporangiales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS2_k127_521537_3	710685.MycrhN_1776	1.114e-24	104.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
HSJS2_k127_522431_2	221288.JH992901_gene2456	1.721e-62	224.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria,1JIE9@1189|Stigonemataceae	1117|Cyanobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
HSJS2_k127_522431_4	1111069.TCCBUS3UF1_6890	4.267e-27	126.0	COG0477@1|root,COG2814@2|Bacteria,1WJC5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS2_k127_522431_5	272560.BPSS2332	5.088e-22	102.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2VV05@28216|Betaproteobacteria,1K1RQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
HSJS2_k127_522431_3	479434.Sthe_3043	1.972e-54	203.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS2_k127_522431_1	196162.Noca_2581	2.924e-67	257.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,4DSF9@85009|Propionibacteriales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HSJS2_k127_522431_0	479434.Sthe_2199	3.617e-175	580.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	200795|Chloroflexi	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
HSJS2_k127_522431_6	1267533.KB906742_gene675	5.114e-05	50.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y6UN@57723|Acidobacteria	57723|Acidobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_52509_2	1071073.KI530534_gene841	3.014e-06	53.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,1ZHEA@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
HSJS2_k127_52509_1	861299.J421_1645	9.888e-36	142.0	2A4CF@1|root,30SY3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
HSJS2_k127_52509_0	102129.Lepto7375DRAFT_1220	6.099e-130	427.0	COG1960@1|root,COG1960@2|Bacteria,1G4UB@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_52875_4	1123377.AUIV01000020_gene2486	6.245e-06	49.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1RPWM@1236|Gammaproteobacteria,1X3IU@135614|Xanthomonadales	135614|Xanthomonadales	S	phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
HSJS2_k127_52875_3	1128421.JAGA01000001_gene2460	1.958e-40	164.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
HSJS2_k127_52875_2	479432.Sros_7585	1.309e-40	168.0	COG0491@1|root,COG0491@2|Bacteria,2GMSA@201174|Actinobacteria,4EKII@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_52875_0	479434.Sthe_2637	1.78e-50	192.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi,27Z2V@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS2_k127_52875_1	321327.CYA_0798	1.615e-43	164.0	COG0328@1|root,COG0328@2|Bacteria,1G12J@1117|Cyanobacteria,1GYK3@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
HSJS2_k127_533882_0	1125863.JAFN01000001_gene580	2.721e-63	229.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HSJS2_k127_533882_1	1429916.X566_23700	1.42e-55	206.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	rutD	GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.1.1.24,3.4.11.5,4.1.1.44	ko:K01055,ko:K01259,ko:K09023,ko:K14727,ko:K16434	ko00240,ko00330,ko00362,ko01055,ko01100,ko01120,ko01220,map00240,map00330,map00362,map01055,map01100,map01120,map01220	M00568	R00135,R02991,R03470,R09983	RC00825,RC00938,RC02769	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iEC55989_1330.EC55989_1120,iECO26_1355.ECO26_1247,iECUMN_1333.ECUMN_1192,iSF_1195.SF1012,iSFxv_1172.SFxv_1098,iSSON_1240.SSON_1027,iS_1188.S1082,ic_1306.c1146	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,CMD
HSJS2_k127_533882_2	471853.Bcav_0657	7.316e-47	177.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
HSJS2_k127_542838_1	1211815.CBYP010000073_gene3651	1.377e-84	299.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4ESAG@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.6	-	-	MMPL
HSJS2_k127_542838_0	324602.Caur_1931	2.885e-125	413.0	COG0304@1|root,COG0304@2|Bacteria,2G7RK@200795|Chloroflexi,376IR@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HSJS2_k127_542838_4	1528106.JRJE01000001_gene2142	4.787e-05	56.0	COG0664@1|root,COG0664@2|Bacteria,1R2E1@1224|Proteobacteria	1224|Proteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
HSJS2_k127_542838_3	1121121.KB894290_gene1855	6.029e-32	143.0	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,26WHE@186822|Paenibacillaceae	91061|Bacilli	S	Patatin-like phospholipase	ylbK	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HSJS2_k127_542838_2	1530186.JQEY01000005_gene3554	3.487e-34	141.0	COG0189@1|root,COG2843@1|root,COG0189@2|Bacteria,COG2843@2|Bacteria,1MVN2@1224|Proteobacteria,2TUT9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	HJ	Cyanophycin synthetase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	CPSase_L_D2,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,PGA_cap,RimK
HSJS2_k127_54841_0	472759.Nhal_2900	0.0	1154.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HSJS2_k127_54841_3	1303518.CCALI_02179	1.48e-46	179.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HSJS2_k127_54841_4	326427.Cagg_1130	1.867e-40	166.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HSJS2_k127_54841_1	266117.Rxyl_2548	1.326e-103	357.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HSJS2_k127_54841_2	1306990.BARG01000084_gene8465	5.459e-63	228.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria	201174|Actinobacteria	P	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
HSJS2_k127_554729_0	383372.Rcas_2575	2.479e-45	182.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G8ES@200795|Chloroflexi,3759V@32061|Chloroflexia	32061|Chloroflexia	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
HSJS2_k127_55594_1	1382306.JNIM01000001_gene3871	1.769e-30	130.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HSJS2_k127_55594_0	436308.Nmar_1385	6.272e-85	289.0	COG0731@1|root,arCOG00953@2157|Archaea	2157|Archaea	C	Radical SAM domain protein	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HSJS2_k127_556875_4	1210045.ALNP01000018_gene2223	1.818e-05	50.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HSJS2_k127_556875_1	1118054.CAGW01000046_gene1567	9.024e-128	422.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,26R6P@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
HSJS2_k127_556875_0	344747.PM8797T_10544	1.498e-131	430.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
HSJS2_k127_556875_2	479434.Sthe_1251	1.343e-71	251.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi,27Y7X@189775|Thermomicrobia	189775|Thermomicrobia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HSJS2_k127_556875_3	324602.Caur_0351	1.273e-68	244.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HSJS2_k127_561524_2	929712.KI912613_gene4284	1.085e-36	144.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CPKV@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HSJS2_k127_561524_0	1128421.JAGA01000002_gene1561	1.031e-67	242.0	COG0077@1|root,COG0077@2|Bacteria,2NR2C@2323|unclassified Bacteria	2|Bacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
HSJS2_k127_561524_1	373903.Hore_04870	8.691e-44	170.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,3WAJM@53433|Halanaerobiales	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HSJS2_k127_566607_2	1051632.TPY_3474	6.469e-63	227.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WCHN@538999|Clostridiales incertae sedis	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
HSJS2_k127_566607_1	1128421.JAGA01000003_gene2990	2.029e-105	357.0	COG0155@1|root,COG0155@2|Bacteria,2NPHB@2323|unclassified Bacteria	2|Bacteria	P	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1	ko:K00366	ko00910,ko01120,map00910,map01120	M00531	R00790	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HSJS2_k127_566607_3	2903.EOD24873	3.907e-26	115.0	COG0155@1|root,KOG0560@2759|Eukaryota	2759|Eukaryota	P	sulfite reductase (ferredoxin) activity	NIR	GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0010035,GO:0010167,GO:0016020,GO:0016491,GO:0016661,GO:0016662,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0050421,GO:0050896,GO:0055114,GO:0098809,GO:1901698,GO:1901700	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
HSJS2_k127_566607_0	1122939.ATUD01000001_gene392	3.385e-218	701.0	COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,2GJCK@201174|Actinobacteria,4CPIT@84995|Rubrobacteria	84995|Rubrobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
HSJS2_k127_566607_4	641524.ADICYQ_5497	2.13e-20	92.0	COG2223@1|root,COG2223@2|Bacteria,4NETE@976|Bacteroidetes,47MEV@768503|Cytophagia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
HSJS2_k127_56940_0	378806.STAUR_3903	2.65e-101	368.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6,2.3.3.15	ko:K01652,ko:K03852	ko00290,ko00430,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00430,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R05651,R08648	RC00027,RC00106,RC01192,RC02744,RC02893,RC02903,RC02909	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS2_k127_56940_1	1415780.JPOG01000001_gene2733	3.029e-65	243.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
HSJS2_k127_56940_2	680198.SCAB_71461	3.375e-50	189.0	COG0300@1|root,COG0300@2|Bacteria,2I2ZU@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_57905_0	1382306.JNIM01000001_gene3473	5.734e-106	348.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HSJS2_k127_57905_2	1329516.JPST01000005_gene1264	7.083e-18	88.0	2CIA1@1|root,3413B@2|Bacteria,1VXTX@1239|Firmicutes,4HXI2@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_57905_1	867903.ThesuDRAFT_00144	1.389e-18	92.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
HSJS2_k127_58846_10	572547.Amico_1203	7.264e-07	58.0	COG4655@1|root,COG4655@2|Bacteria	2|Bacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
HSJS2_k127_58846_7	1121472.AQWN01000010_gene596	6.154e-16	88.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,262WB@186807|Peptococcaceae	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
HSJS2_k127_58846_3	509191.AEDB02000063_gene453	5.972e-40	164.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,3WKMS@541000|Ruminococcaceae	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
HSJS2_k127_58846_0	58123.JOFJ01000025_gene3389	2.713e-138	459.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system protein e	flpF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
HSJS2_k127_58846_6	1123288.SOV_2c07710	2.586e-31	138.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,4H3YR@909932|Negativicutes	909932|Negativicutes	U	Type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HSJS2_k127_58846_4	574087.Acear_0238	2.494e-36	149.0	COG2064@1|root,COG2064@2|Bacteria,1V2T1@1239|Firmicutes,24GQ4@186801|Clostridia	186801|Clostridia	NU	PFAM type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HSJS2_k127_58846_9	926550.CLDAP_35680	2.552e-10	69.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pppA	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HSJS2_k127_58846_8	926566.Terro_3228	2.088e-13	84.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
HSJS2_k127_58846_12	1454010.JEOE01000034_gene1816	0.0001271	55.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4F17R@85016|Cellulomonadaceae	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
HSJS2_k127_58846_11	1297742.A176_07647	1.215e-06	61.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
HSJS2_k127_58846_5	298653.Franean1_5465	4.483e-33	140.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria,4EWVP@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
HSJS2_k127_58846_2	1313172.YM304_07760	6.553e-47	177.0	COG0704@1|root,COG0704@2|Bacteria,2H63V@201174|Actinobacteria	201174|Actinobacteria	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
HSJS2_k127_58846_1	1313172.YM304_07770	6.223e-104	349.0	COG1283@1|root,COG1283@2|Bacteria,2IAMX@201174|Actinobacteria	201174|Actinobacteria	P	Na+/Pi-cotransporter	nptA	-	-	ko:K03324,ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1,2.A.58.2	-	-	Na_Pi_cotrans
HSJS2_k127_596635_1	1122609.AUGT01000032_gene449	4.201e-70	251.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4DUGI@85009|Propionibacteriales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_596635_2	118005.AWNK01000008_gene470	6.888e-29	117.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HSJS2_k127_596635_0	525904.Tter_0396	1.033e-79	277.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_597956_9	1123504.JQKD01000012_gene1259	8.255e-17	80.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VNG0@28216|Betaproteobacteria,4ADU9@80864|Comamonadaceae	28216|Betaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_597956_5	312284.A20C1_03378	1.033e-43	164.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_597956_3	1126627.BAWE01000004_gene2380	3.564e-68	241.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,2TUPH@28211|Alphaproteobacteria,3JRRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_597956_7	1500894.JQNN01000001_gene4052	1.742e-25	113.0	COG0431@1|root,COG0431@2|Bacteria,1MX40@1224|Proteobacteria,2VQFT@28216|Betaproteobacteria,4746N@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	NAD(P)H-dependent FMN reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
HSJS2_k127_597956_12	158500.BV97_00011	5.736e-05	46.0	COG2141@1|root,COG2141@2|Bacteria,1MX4E@1224|Proteobacteria,2TSGA@28211|Alphaproteobacteria,2KD53@204457|Sphingomonadales	204457|Sphingomonadales	C	Flavin-dependent oxidoreductase, methylene-tetrahydromethanopterin reductase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HSJS2_k127_597956_1	765913.ThidrDRAFT_3335	2.196e-96	324.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1WW2T@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
HSJS2_k127_597956_10	1445613.JALM01000036_gene2839	1.373e-13	76.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4E0MG@85010|Pseudonocardiales	201174|Actinobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_597956_6	1313172.YM304_11520	6.524e-26	118.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CN4A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
HSJS2_k127_597956_0	1123279.ATUS01000001_gene1182	1.792e-132	438.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1J5HJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HSJS2_k127_597956_2	1246995.AFR_08180	5.283e-94	317.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DAC8@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
HSJS2_k127_597956_4	42256.RradSPS_1108	3.416e-52	196.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4CPJK@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
HSJS2_k127_597956_11	1055815.AYYA01000055_gene1093	1.059e-11	70.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1NR3M@1224|Proteobacteria,1RY7C@1236|Gammaproteobacteria,3NT26@468|Moraxellaceae	1236|Gammaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	hcaD	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C,Rieske
HSJS2_k127_597956_8	319003.Bra1253DRAFT_00382	5.727e-20	93.0	COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
HSJS2_k127_601908_3	1313172.YM304_03500	4.713e-35	142.0	COG1162@1|root,COG1162@2|Bacteria,2GMDX@201174|Actinobacteria	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
HSJS2_k127_601908_1	91464.S7335_3783	1.324e-43	166.0	COG0563@1|root,COG0563@2|Bacteria,1G696@1117|Cyanobacteria	1117|Cyanobacteria	F	COG0563 Adenylate kinase and related	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,PduV-EutP,SKI
HSJS2_k127_601908_0	1459636.NTE_03049	9.397e-52	190.0	COG0122@1|root,arCOG00464@2157|Archaea	2157|Archaea	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HSJS2_k127_601908_2	880072.Desac_1681	2.568e-37	144.0	COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria	1224|Proteobacteria	J	Methionyl-tRNA formyltransferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HSJS2_k127_611646_1	1382356.JQMP01000004_gene65	7.257e-122	405.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,27XK6@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HSJS2_k127_611646_0	479434.Sthe_1611	1.828e-206	648.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HSJS2_k127_611646_2	767029.HMPREF9154_2318	3.81e-18	84.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4DS40@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HSJS2_k127_611646_3	243164.DET0995	2.43e-08	59.0	COG0690@1|root,COG0690@2|Bacteria,2G9VX@200795|Chloroflexi,34DH3@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HSJS2_k127_611646_4	525903.Taci_1512	3.161e-07	54.0	COG0250@1|root,COG0250@2|Bacteria,3TA7Y@508458|Synergistetes	508458|Synergistetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HSJS2_k127_619092_0	1169161.KB897716_gene5818	4.673e-49	183.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS2_k127_619092_1	926554.KI912671_gene390	9.525e-33	145.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1WM3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_4,PAS_8
HSJS2_k127_619092_4	1121123.AUAO01000003_gene2520	1.555e-05	56.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,2KFQK@204458|Caulobacterales	204458|Caulobacterales	KQ	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
HSJS2_k127_619092_2	1496688.ER33_00560	5.519e-24	109.0	COG0558@1|root,COG0558@2|Bacteria,1GD9W@1117|Cyanobacteria	1117|Cyanobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HSJS2_k127_619092_3	909943.HIMB100_00010870	2.63e-08	64.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,2TZY0@28211|Alphaproteobacteria,4BQUY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HSJS2_k127_628985_4	1089546.AQUI01000002_gene4369	1.694e-05	53.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4095C@622450|Actinopolysporales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
HSJS2_k127_628985_3	562970.Btus_0372	4.776e-13	81.0	COG2030@1|root,COG2030@2|Bacteria,1V4PQ@1239|Firmicutes,4HGYW@91061|Bacilli,278N3@186823|Alicyclobacillaceae	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
HSJS2_k127_628985_2	76114.ebA5293	7.532e-21	106.0	COG0613@1|root,COG0613@2|Bacteria,1RF04@1224|Proteobacteria,2W16S@28216|Betaproteobacteria,2KYJS@206389|Rhodocyclales	206389|Rhodocyclales	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
HSJS2_k127_628985_1	1382356.JQMP01000003_gene1363	1.386e-52	202.0	COG0491@1|root,COG0491@2|Bacteria,2GBAB@200795|Chloroflexi,27YH3@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_628985_0	479434.Sthe_3015	6.844e-117	395.0	COG0318@1|root,COG0318@2|Bacteria,2G7PF@200795|Chloroflexi,27XJD@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
HSJS2_k127_643175_2	1282876.BAOK01000002_gene343	3.103e-18	85.0	COG0667@1|root,COG0667@2|Bacteria,1R7AM@1224|Proteobacteria,2U0JN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS2_k127_643175_0	1345697.M493_15880	5.63e-112	379.0	COG2272@1|root,COG2272@2|Bacteria,1UXY5@1239|Firmicutes,4HCKV@91061|Bacilli,1WEY8@129337|Geobacillus	91061|Bacilli	I	Carboxylesterase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
HSJS2_k127_643175_1	102129.Lepto7375DRAFT_2009	4.579e-86	301.0	COG1231@1|root,COG1231@2|Bacteria,1GCEZ@1117|Cyanobacteria,1HH89@1150|Oscillatoriales	1117|Cyanobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
HSJS2_k127_664408_1	31234.CRE00589	7.668e-83	292.0	COG2030@1|root,2QPX4@2759|Eukaryota,39K2N@33154|Opisthokonta,3BD1Y@33208|Metazoa,3CX6W@33213|Bilateria,40AXE@6231|Nematoda,1KU33@119089|Chromadorea,40ZMD@6236|Rhabditida	33208|Metazoa	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	HSD17B4	GO:0000003,GO:0000038,GO:0002064,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003824,GO:0003857,GO:0004303,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007548,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008209,GO:0008210,GO:0008406,GO:0008584,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009888,GO:0009987,GO:0010033,GO:0010817,GO:0010883,GO:0010888,GO:0014070,GO:0016042,GO:0016054,GO:0016125,GO:0016137,GO:0016138,GO:0016229,GO:0016491,GO:0016508,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019752,GO:0022414,GO:0022611,GO:0030154,GO:0030258,GO:0030283,GO:0030855,GO:0031907,GO:0031974,GO:0032501,GO:0032502,GO:0032787,GO:0032879,GO:0033764,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034641,GO:0034754,GO:0035337,GO:0035383,GO:0036111,GO:0036112,GO:0040008,GO:0040024,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0043053,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044550,GO:0044594,GO:0045137,GO:0045927,GO:0046395,GO:0046483,GO:0046546,GO:0046661,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048545,GO:0048580,GO:0048582,GO:0048608,GO:0048638,GO:0048639,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060008,GO:0060009,GO:0060429,GO:0061062,GO:0061063,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901568,GO:1901575,GO:1901576,GO:1901615,GO:1901657,GO:1901659,GO:1902652,GO:1904069,GO:1904070,GO:1905952,GO:1905953,GO:2000026	1.1.1.35,4.2.1.107,4.2.1.119	ko:K12405	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R04809,R04810,R04812,R04813,R09698	RC00089,RC00770,RC01217	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas,SCP2,adh_short
HSJS2_k127_664408_3	1336235.JAEG01000009_gene2723	8.078e-26	112.0	COG0454@1|root,COG0456@2|Bacteria,1N1SU@1224|Proteobacteria,2UA9R@28211|Alphaproteobacteria,4BEMV@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HSJS2_k127_664408_2	1957.JODX01000012_gene368	5.626e-48	181.0	COG0346@1|root,COG0346@2|Bacteria,2GRGB@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
HSJS2_k127_664408_4	1283287.KB822577_gene3431	8.232e-18	87.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,4DSBC@85009|Propionibacteriales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HSJS2_k127_664408_0	317936.Nos7107_5285	1.095e-101	335.0	COG0667@1|root,COG0667@2|Bacteria,1G3WV@1117|Cyanobacteria,1HMPK@1161|Nostocales	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
HSJS2_k127_677364_1	43759.JNWK01000016_gene322	1.157e-15	91.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_677364_0	525904.Tter_1709	1.325e-133	447.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NQNK@2323|unclassified Bacteria	2|Bacteria	EU	Peptidase S9 prolyl oligopeptidase active site	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
HSJS2_k127_688662_1	1382356.JQMP01000003_gene1295	9.187e-134	438.0	COG0001@1|root,COG0001@2|Bacteria,2G7UK@200795|Chloroflexi,27XN6@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS2_k127_688662_4	697281.Mahau_2933	5.62e-06	55.0	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,25EYA@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HSJS2_k127_688662_2	1122611.KB903987_gene3955	1.792e-45	178.0	COG1670@1|root,COG1670@2|Bacteria,2H4AD@201174|Actinobacteria,4EJIU@85012|Streptosporangiales	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_688662_0	479434.Sthe_3485	3.922e-186	592.0	COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
HSJS2_k127_688662_3	1382306.JNIM01000001_gene1827	3.004e-24	108.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi	200795|Chloroflexi	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_68994_5	166318.Syn8016DRAFT_0120	4.046e-16	78.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1H0EV@1129|Synechococcus	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HSJS2_k127_68994_6	875328.JDM601_0158	3.256e-14	77.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,23A0Q@1762|Mycobacteriaceae	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HSJS2_k127_68994_1	102129.Lepto7375DRAFT_2096	6.078e-77	274.0	COG4292@1|root,COG4292@2|Bacteria,1G40Y@1117|Cyanobacteria,1HA5V@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
HSJS2_k127_68994_0	1123389.ATXJ01000016_gene54	8.564e-93	316.0	COG0416@1|root,COG0416@2|Bacteria,1WJ6C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HSJS2_k127_68994_4	479434.Sthe_0981	4.766e-27	121.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,27Y5W@189775|Thermomicrobia	189775|Thermomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS2_k127_68994_3	102129.Lepto7375DRAFT_2915	3.442e-53	194.0	COG0503@1|root,COG0503@2|Bacteria,1G508@1117|Cyanobacteria,1HAKH@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HSJS2_k127_68994_2	1382356.JQMP01000001_gene977	1.22e-60	220.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi,27XYC@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
HSJS2_k127_690221_0	1358423.N180_00950	5.814e-65	225.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IV63@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009986,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HSJS2_k127_690221_1	1167006.UWK_03033	3.668e-53	206.0	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1QW3X@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheR,CheR_N,PAS,PAS_3,PAS_4,PAS_9
HSJS2_k127_690221_2	251221.35212227	1.509e-48	192.0	COG0664@1|root,COG3852@1|root,COG0664@2|Bacteria,COG3852@2|Bacteria,1GQDB@1117|Cyanobacteria	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
HSJS2_k127_691207_4	517722.AEUE01000001_gene2842	2.657e-20	95.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,2KCNC@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HSJS2_k127_691207_0	479434.Sthe_0537	6.898e-66	237.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,27XUY@189775|Thermomicrobia	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS2_k127_691207_3	1229172.JQFA01000004_gene1000	1.849e-29	126.0	COG2320@1|root,COG2320@2|Bacteria,1G553@1117|Cyanobacteria,1HBA5@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0157	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
HSJS2_k127_691207_1	1121481.AUAS01000002_gene3527	2.179e-54	210.0	COG1524@1|root,COG1524@2|Bacteria,4PAJU@976|Bacteroidetes,47TWN@768503|Cytophagia	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HSJS2_k127_691207_2	477641.MODMU_1794	1.792e-30	134.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
HSJS2_k127_69543_4	935948.KE386495_gene1477	4.648e-33	131.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,42G8M@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HSJS2_k127_69543_2	373903.Hore_02460	5.819e-47	180.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WAPJ@53433|Halanaerobiales	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HSJS2_k127_69543_1	765420.OSCT_0173	5.494e-48	182.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi,375JX@32061|Chloroflexia	32061|Chloroflexia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HSJS2_k127_69543_3	935948.KE386495_gene1483	1.32e-41	156.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,42GJW@68295|Thermoanaerobacterales	186801|Clostridia	J	ribosomal protein l17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HSJS2_k127_69543_0	1382306.JNIM01000001_gene3521	3.921e-62	223.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HSJS2_k127_696645_1	448385.sce2331	5.418e-241	760.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YXS9@29|Myxococcales	28221|Deltaproteobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1
HSJS2_k127_696645_2	1100720.ALKN01000052_gene507	1.016e-108	367.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS2_k127_696645_5	1382306.JNIM01000001_gene846	7.69e-24	104.0	COG3224@1|root,COG3224@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
HSJS2_k127_696645_0	867845.KI911784_gene3323	0.0	1152.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,374T1@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HSJS2_k127_696645_3	588596.U9T1R7	9.778e-100	339.0	COG1473@1|root,2QQPD@2759|Eukaryota,38CZV@33154|Opisthokonta,3NUFT@4751|Fungi	4751|Fungi	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HSJS2_k127_696645_4	1382306.JNIM01000001_gene3374	9.558e-47	187.0	COG2133@1|root,COG2133@2|Bacteria,2G7VF@200795|Chloroflexi	200795|Chloroflexi	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
HSJS2_k127_696645_6	305700.B447_05608	1.156e-21	96.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,2KWA8@206389|Rhodocyclales	206389|Rhodocyclales	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HSJS2_k127_697189_4	1049564.TevJSym_ac02040	4.381e-16	83.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1J67Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Yqey-like protein	lporfX	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HSJS2_k127_697189_5	316274.Haur_2659	8.214e-13	71.0	COG0828@1|root,COG0828@2|Bacteria,2G7EY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HSJS2_k127_697189_7	1206731.BAGB01000167_gene915	2.238e-07	53.0	2ECT0@1|root,336QK@2|Bacteria,2IKM4@201174|Actinobacteria,4G54K@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_697189_8	686340.Metal_2267	2.337e-07	63.0	COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,1SFGZ@1236|Gammaproteobacteria,1XFNP@135618|Methylococcales	135618|Methylococcales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K19344	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
HSJS2_k127_697189_6	867903.ThesuDRAFT_02246	1.119e-09	70.0	COG2010@1|root,COG2010@2|Bacteria,1VX6C@1239|Firmicutes,251IR@186801|Clostridia	186801|Clostridia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HSJS2_k127_697189_3	644966.Tmar_0323	1.689e-25	115.0	COG0723@1|root,COG0723@2|Bacteria,1VM4K@1239|Firmicutes,24X5X@186801|Clostridia	186801|Clostridia	C	PFAM Rieske 2Fe-2S domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
HSJS2_k127_697189_2	292459.STH3147	1.095e-34	145.0	COG1290@1|root,COG1290@2|Bacteria,1USWS@1239|Firmicutes,2501X@186801|Clostridia	186801|Clostridia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
HSJS2_k127_697189_0	485913.Krac_6667	7.434e-99	328.0	COG1290@1|root,COG1290@2|Bacteria,2G8QQ@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
HSJS2_k127_697189_1	640132.Srot_2555	2.87e-48	177.0	COG1215@1|root,COG2246@1|root,COG1215@2|Bacteria,COG2246@2|Bacteria,2GJTE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
HSJS2_k127_70368_2	552811.Dehly_1577	6.672e-86	292.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi,34CSK@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HSJS2_k127_70368_0	552811.Dehly_0042	3.569e-148	481.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,34CW8@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
HSJS2_k127_70368_5	591001.Acfer_1232	2.473e-45	178.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4H272@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HSJS2_k127_70368_1	1123239.KB898638_gene196	2.477e-143	464.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli	91061|Bacilli	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
HSJS2_k127_70368_6	1463857.JOFZ01000016_gene1070	1.341e-08	63.0	COG1246@1|root,COG1246@2|Bacteria,2IP00@201174|Actinobacteria	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS2_k127_70368_4	693977.Deipr_1689	3.892e-55	201.0	COG0125@1|root,COG0125@2|Bacteria,1WK3U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
HSJS2_k127_70368_3	357808.RoseRS_3233	1.205e-58	213.0	COG1847@1|root,COG3854@1|root,COG1847@2|Bacteria,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi,375BX@32061|Chloroflexia	32061|Chloroflexia	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,R3H
HSJS2_k127_711695_0	1278078.G419_25964	5.625e-132	451.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4FW1X@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_712775_0	1382306.JNIM01000001_gene2563	6.385e-112	376.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
HSJS2_k127_712775_3	1274374.CBLK010000026_gene2931	2.907e-06	56.0	COG1713@1|root,COG2318@1|root,COG1713@2|Bacteria,COG2318@2|Bacteria,1V44H@1239|Firmicutes,4HH8H@91061|Bacilli,26VP4@186822|Paenibacillaceae	91061|Bacilli	H	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HSJS2_k127_712775_2	33876.JNXY01000005_gene8701	2.646e-71	256.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria,4DDQV@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HSJS2_k127_712775_1	1125863.JAFN01000001_gene3450	2.896e-87	299.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HSJS2_k127_714589_3	637390.AFOH01000158_gene304	3.716e-10	68.0	2E48M@1|root,32Z4G@2|Bacteria,1N6NZ@1224|Proteobacteria,1T8S2@1236|Gammaproteobacteria,2NDBV@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_714589_1	247156.NFA_30970	6.177e-17	87.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
HSJS2_k127_714589_0	309801.trd_1644	1.407e-53	193.0	2DBIJ@1|root,2Z9G2@2|Bacteria,2G896@200795|Chloroflexi,27XN4@189775|Thermomicrobia	189775|Thermomicrobia	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
HSJS2_k127_715153_2	1123023.JIAI01000003_gene2846	3.736e-88	301.0	COG1028@1|root,COG1028@2|Bacteria,2H8QY@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS2_k127_715153_3	1122611.KB903948_gene6718	1.133e-42	181.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
HSJS2_k127_715153_4	1146883.BLASA_3642	0.0006113	50.0	COG1215@1|root,COG1215@2|Bacteria,2GKFI@201174|Actinobacteria,4ESRY@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	bcsA	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,PilZ
HSJS2_k127_715153_0	1205680.CAKO01000035_gene318	7.468e-192	610.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,2JZBX@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
HSJS2_k127_715153_1	272943.RSP_1558	2.917e-94	316.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,2TVRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HSJS2_k127_720513_0	103733.JNYO01000001_gene222	1.734e-119	397.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4E0JB@85010|Pseudonocardiales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HSJS2_k127_720513_3	1077974.GOEFS_132_00180	0.0002418	49.0	COG0425@1|root,COG0425@2|Bacteria,2GSNH@201174|Actinobacteria	201174|Actinobacteria	O	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HSJS2_k127_720513_1	1121377.KB906405_gene135	3.194e-106	360.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HSJS2_k127_720513_2	1254432.SCE1572_30260	2.244e-17	85.0	COG0300@1|root,COG0300@2|Bacteria,1QUNR@1224|Proteobacteria,43CVE@68525|delta/epsilon subdivisions,2X83C@28221|Deltaproteobacteria,2Z3K2@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS2_k127_726452_0	1288826.MSNKSG1_14177	1.33e-93	324.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	CorA-like Mg2+ transporter protein	zntB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
HSJS2_k127_726452_1	315749.Bcer98_4017	6.914e-31	133.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus	91061|Bacilli	M	Mechanosensitive ion channel	ykuT	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HSJS2_k127_726452_2	543632.JOJL01000015_gene8687	1.998e-23	102.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4DDYY@85008|Micromonosporales	201174|Actinobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HSJS2_k127_729392_3	552811.Dehly_1327	2.273e-08	56.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,34DAV@301297|Dehalococcoidia	301297|Dehalococcoidia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HSJS2_k127_729392_2	953739.SVEN_2545	1.625e-10	70.0	COG0125@1|root,COG0125@2|Bacteria,2I3EK@201174|Actinobacteria	201174|Actinobacteria	F	Chloramphenicol phosphotransferase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,CPT
HSJS2_k127_729392_0	765420.OSCT_1304	9.786e-76	269.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HSJS2_k127_729392_1	429009.Adeg_1873	9.389e-11	66.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,42ESA@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HSJS2_k127_735440_1	177437.HRM2_35240	2.062e-87	312.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
HSJS2_k127_735440_4	1382356.JQMP01000003_gene1998	7.645e-52	199.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi,27XZP@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HSJS2_k127_735440_2	1121033.AUCF01000015_gene1442	1.363e-82	284.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2TVMG@28211|Alphaproteobacteria,2JPY6@204441|Rhodospirillales	204441|Rhodospirillales	L	COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
HSJS2_k127_735440_0	552811.Dehly_1200	0.0	1050.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi,34CMC@301297|Dehalococcoidia	301297|Dehalococcoidia	O	C-terminal, D2-small domain, of ClpB protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HSJS2_k127_735440_3	479434.Sthe_0495	3.099e-65	237.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,27XFV@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HSJS2_k127_757047_1	1382306.JNIM01000001_gene1327	2.075e-64	227.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HSJS2_k127_757047_4	649831.L083_7773	3.155e-16	85.0	COG3557@1|root,COG3557@2|Bacteria,2IQ8M@201174|Actinobacteria,4DCQR@85008|Micromonosporales	201174|Actinobacteria	J	domain protein associated with RNAses G and E	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
HSJS2_k127_757047_0	552811.Dehly_0351	1.047e-144	473.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,34CVS@301297|Dehalococcoidia	301297|Dehalococcoidia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
HSJS2_k127_757047_5	1173021.ALWA01000008_gene1517	2.967e-12	75.0	COG4454@1|root,COG4454@2|Bacteria,1G83X@1117|Cyanobacteria	1117|Cyanobacteria	P	Sulfocyanin (SoxE) domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,SoxE
HSJS2_k127_757047_2	1463857.JOFZ01000004_gene2679	5.751e-62	231.0	COG1878@1|root,COG1878@2|Bacteria,2GK9Y@201174|Actinobacteria	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
HSJS2_k127_757047_3	42256.RradSPS_3026	3.732e-25	117.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4CT57@84995|Rubrobacteria	84995|Rubrobacteria	G	COG COG1070 Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism	-	-	2.7.1.53	ko:K00880	ko00040,ko00053,map00040,map00053	-	R01901,R07127	RC00002,RC00017,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
HSJS2_k127_778131_5	65497.JODV01000010_gene2651	1.881e-09	68.0	COG3386@1|root,COG3386@2|Bacteria,2GNM1@201174|Actinobacteria,4E2FT@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SGL
HSJS2_k127_778131_0	552811.Dehly_0378	9.746e-117	388.0	COG2524@1|root,COG4175@1|root,COG2524@2|Bacteria,COG4175@2|Bacteria	2|Bacteria	E	quaternary-ammonium-compound-transporting ATPase activity	opuAA	-	3.6.1.1,3.6.3.32	ko:K02000,ko:K15986	ko00190,ko02010,map00190,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS,DHH,DHHA2,DRTGG
HSJS2_k127_778131_2	522772.Dacet_2037	4.044e-92	310.0	COG4176@1|root,COG4176@2|Bacteria,2GG9Y@200930|Deferribacteres	200930|Deferribacteres	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
HSJS2_k127_778131_1	552811.Dehly_0376	9.895e-116	395.0	COG2113@1|root,COG2113@2|Bacteria,2G9P4@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
HSJS2_k127_778131_6	1069534.LRC_05890	0.0002033	49.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae	91061|Bacilli	S	Cyclic-di-AMP receptor	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
HSJS2_k127_778131_4	394221.Mmar10_2330	4.89e-16	89.0	2CDDX@1|root,3058G@2|Bacteria,1QYT0@1224|Proteobacteria,2UETN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Alkylmercury lyase	-	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	MerB
HSJS2_k127_778131_3	314275.MADE_1005595	1.069e-22	107.0	2CDDX@1|root,3058G@2|Bacteria,1QYT0@1224|Proteobacteria	1224|Proteobacteria	E	Helix-turn-helix domain of alkylmercury lyase	-	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	HTH_15,MerB
HSJS2_k127_786350_1	1232410.KI421428_gene1178	6.992e-43	163.0	COG0596@1|root,COG0596@2|Bacteria,1RGAP@1224|Proteobacteria,42XWU@68525|delta/epsilon subdivisions,2WSMY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS2_k127_786350_0	290512.Paes_2232	8.637e-85	298.0	COG1073@1|root,COG1073@2|Bacteria,1FF06@1090|Chlorobi	1090|Chlorobi	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_786350_4	1454004.AW11_03959	3.962e-11	75.0	COG2154@1|root,COG2154@2|Bacteria	2|Bacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a,TIR_2
HSJS2_k127_786350_2	2002.JOEQ01000005_gene3252	4.618e-22	110.0	COG4995@1|root,COG4995@2|Bacteria,2IJMG@201174|Actinobacteria,4ENBK@85012|Streptosporangiales	201174|Actinobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
HSJS2_k127_786350_3	765420.OSCT_3185	4.914e-13	81.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2G86V@200795|Chloroflexi,374S2@32061|Chloroflexia	32061|Chloroflexia	KLT	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
HSJS2_k127_797473_0	1120936.KB907216_gene3740	3.673e-65	228.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4EGKE@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_797473_1	1211815.CBYP010000063_gene1857	5.324e-38	157.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,4EXAK@85013|Frankiales	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
HSJS2_k127_797473_2	1125863.JAFN01000001_gene2040	5.489e-28	125.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,42QER@68525|delta/epsilon subdivisions,2WM9B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS2_k127_816743_0	1231241.Mc24_08644	7.371e-86	294.0	COG0552@1|root,COG0552@2|Bacteria,2GBXG@200918|Thermotogae	200918|Thermotogae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HSJS2_k127_816743_1	324602.Caur_1339	2.698e-57	225.0	COG0457@1|root,COG5427@1|root,COG0457@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,37551@32061|Chloroflexia	32061|Chloroflexia	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
HSJS2_k127_816743_2	1382356.JQMP01000004_gene288	1.28e-38	153.0	COG4745@1|root,COG4745@2|Bacteria,2G6HI@200795|Chloroflexi,27XK8@189775|Thermomicrobia	189775|Thermomicrobia	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HSJS2_k127_820091_3	103733.JNYO01000003_gene8083	1.398e-17	86.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4E1VY@85010|Pseudonocardiales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HSJS2_k127_820091_2	552811.Dehly_0084	1.075e-20	94.0	COG2052@1|root,COG2052@2|Bacteria,2GAV2@200795|Chloroflexi,34DEP@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF370)	-	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HSJS2_k127_820091_0	316274.Haur_0970	1.397e-133	440.0	COG0128@1|root,COG0128@2|Bacteria,2G5TT@200795|Chloroflexi,375C6@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HSJS2_k127_820091_1	324602.Caur_2517	9.014e-58	214.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,3750B@32061|Chloroflexia	32061|Chloroflexia	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
HSJS2_k127_820091_5	926550.CLDAP_06120	1.018e-10	69.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi	200795|Chloroflexi	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_820091_4	555778.Hneap_1456	3.407e-15	78.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,1WWRR@135613|Chromatiales	135613|Chromatiales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HSJS2_k127_821523_0	867903.ThesuDRAFT_01077	1.805e-78	273.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WCYH@538999|Clostridiales incertae sedis	186801|Clostridia	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HSJS2_k127_821523_1	479434.Sthe_1705	1.189e-63	230.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia	189775|Thermomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HSJS2_k127_821523_2	479434.Sthe_2201	8.499e-55	201.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HSJS2_k127_821523_3	479434.Sthe_1406	1.604e-40	157.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi,27YGM@189775|Thermomicrobia	189775|Thermomicrobia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HSJS2_k127_821523_4	1463917.JODC01000004_gene6276	0.0002551	49.0	COG3339@1|root,COG3339@2|Bacteria,2GZ4K@201174|Actinobacteria	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_860432_0	926569.ANT_03800	8.673e-60	218.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HSJS2_k127_860432_1	311424.DhcVS_348	1.101e-44	182.0	COG1947@1|root,COG1947@2|Bacteria,2G71D@200795|Chloroflexi,34CZT@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HSJS2_k127_863525_2	65672.G4TB02	1.138e-48	184.0	COG0134@1|root,COG0135@1|root,COG0512@1|root,KOG0026@2759|Eukaryota,KOG4201@2759|Eukaryota,KOG4202@2759|Eukaryota,38FIR@33154|Opisthokonta,3NU49@4751|Fungi,3UZN9@5204|Basidiomycota,224SV@155619|Agaricomycetes,3H2VM@355688|Agaricomycetes incertae sedis	4751|Fungi	E	Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities	TRP3	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0004425,GO:0004640,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0033984,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.1.48,4.1.3.27,5.3.1.24	ko:K01656,ko:K13501	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R03508,R03509	RC00010,RC00944,RC00945,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,IGPS,PRAI
HSJS2_k127_863525_0	1303518.CCALI_02665	1.211e-169	550.0	COG0133@1|root,COG0133@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS2_k127_863525_3	326427.Cagg_1931	1.413e-26	118.0	COG3222@1|root,COG3222@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
HSJS2_k127_863525_4	235985.BBPN01000014_gene5516	7.27e-26	116.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria,2NJNR@228398|Streptacidiphilus	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS2_k127_863525_5	1192034.CAP_0198	2.7e-24	109.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS2_k127_863525_1	1166018.FAES_4584	7.062e-66	235.0	COG0535@1|root,COG0535@2|Bacteria,4NIZI@976|Bacteroidetes,47K2I@768503|Cytophagia	976|Bacteroidetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
HSJS2_k127_868696_4	479434.Sthe_1422	1.088e-68	241.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi,27XXK@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HSJS2_k127_868696_0	1321786.HMPREF1992_01868	1.193e-201	650.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4H2IA@909932|Negativicutes	909932|Negativicutes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HSJS2_k127_868696_7	246194.CHY_2544	1.055e-20	100.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,42GKC@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
HSJS2_k127_868696_3	525368.HMPREF0591_3300	2.402e-86	296.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,2360H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phosphotriesterase	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
HSJS2_k127_868696_2	246194.CHY_2542	6.757e-106	359.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,42EZC@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HSJS2_k127_868696_1	1382356.JQMP01000003_gene1994	1.916e-128	419.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,27Y3P@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HSJS2_k127_868696_5	525904.Tter_1040	8.6e-60	213.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HSJS2_k127_868696_6	391625.PPSIR1_00410	1.906e-25	111.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,431IQ@68525|delta/epsilon subdivisions,2WX18@28221|Deltaproteobacteria,2YZ2U@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NACHT,TIR_2,WD40
HSJS2_k127_877837_7	1121123.AUAO01000003_gene2330	6.954e-22	104.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,2KGBQ@204458|Caulobacterales	204458|Caulobacterales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HSJS2_k127_877837_0	357808.RoseRS_2146	2.677e-136	449.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,375A1@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HSJS2_k127_877837_6	767817.Desgi_0603	1.506e-25	120.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,2612S@186807|Peptococcaceae	186801|Clostridia	S	PFAM YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
HSJS2_k127_877837_4	309801.trd_0688	1.026e-62	226.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi,27XJ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
HSJS2_k127_877837_2	879310.HMPREF9162_1483	2.705e-86	296.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H278@909932|Negativicutes	909932|Negativicutes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HSJS2_k127_877837_8	1304284.L21TH_2106	1.445e-21	101.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,36KSY@31979|Clostridiaceae	186801|Clostridia	L	Competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HSJS2_k127_877837_3	292459.STH473	8.893e-64	245.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HSJS2_k127_877837_1	767434.Fraau_0411	4.932e-88	298.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1X3QU@135614|Xanthomonadales	135614|Xanthomonadales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
HSJS2_k127_877837_9	375286.mma_3280	6.136e-13	74.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,474C2@75682|Oxalobacteraceae	28216|Betaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
HSJS2_k127_877837_5	477974.Daud_1638	1.521e-33	138.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HSJS2_k127_883654_0	479434.Sthe_2785	3.984e-55	206.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.8.1.7,4.4.1.16	ko:K03980,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000,ko01011,ko02000	2.A.66.4	-	-	Peptidase_M28,SLH
HSJS2_k127_891935_3	645991.Sgly_2441	4.263e-82	277.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,260S7@186807|Peptococcaceae	186801|Clostridia	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
HSJS2_k127_891935_1	324602.Caur_2260	2.923e-147	476.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HSJS2_k127_891935_2	1469245.JFBG01000027_gene1472	1.365e-131	428.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1X2WV@135613|Chromatiales	1236|Gammaproteobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	3.6.3.24	ko:K02031,ko:K15583,ko:K15587	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HSJS2_k127_891935_0	1123371.ATXH01000013_gene1505	4.286e-220	701.0	COG0441@1|root,COG0441@2|Bacteria,2GH53@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
HSJS2_k127_891935_4	1121481.AUAS01000003_gene3777	7.246e-41	153.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HSJS2_k127_899733_6	269084.syc1663_d	4.742e-25	106.0	COG0573@1|root,COG0573@2|Bacteria,1G1JR@1117|Cyanobacteria,1H466@1129|Synechococcus	1117|Cyanobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HSJS2_k127_899733_1	926550.CLDAP_00820	4.722e-107	355.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HSJS2_k127_899733_0	1246445.ANAY01000030_gene4437	3.572e-117	383.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EM3I@85012|Streptosporangiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HSJS2_k127_899733_4	926569.ANT_01750	3.823e-47	190.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
HSJS2_k127_899733_3	552811.Dehly_1189	6.618e-74	256.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,34D9D@301297|Dehalococcoidia	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS2_k127_899733_5	1280953.HOC_01641	5.251e-37	148.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
HSJS2_k127_899733_2	344747.PM8797T_17307	1.034e-95	321.0	COG1529@1|root,COG1529@2|Bacteria,2IYIN@203682|Planctomycetes	203682|Planctomycetes	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HSJS2_k127_903739_1	290397.Adeh_2484	3.486e-41	157.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
HSJS2_k127_903739_2	1121422.AUMW01000005_gene639	7.803e-39	157.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,261UI@186807|Peptococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HSJS2_k127_903739_0	292459.STH1219	4.033e-123	404.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HSJS2_k127_908079_3	1392838.AWNM01000031_gene13	1.914e-07	53.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJJD@28216|Betaproteobacteria,3T701@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_908079_1	629773.AORY01000012_gene1073	9.726e-91	313.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2K0TN@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS2_k127_908079_2	767817.Desgi_0671	2.364e-74	269.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149,5.3.3.18	ko:K07546,ko:K08299,ko:K15866	ko00360,ko00623,ko01100,ko01120,ko01220,map00360,map00623,map01100,map01120,map01220	M00418	R05599,R09837,R09839,R10675	RC00004,RC00326,RC01095,RC01435,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS2_k127_908079_0	312284.A20C1_03383	1.761e-139	458.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,3UXHJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HSJS2_k127_908079_4	1394178.AWOO02000001_gene1218	0.0002274	44.0	COG1545@1|root,COG1545@2|Bacteria,2IHZR@201174|Actinobacteria	2|Bacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
HSJS2_k127_921387_0	1245471.PCA10_33530	1.663e-45	170.0	COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,1S480@1236|Gammaproteobacteria,1YG26@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
HSJS2_k127_921387_1	479434.Sthe_2009	2.36e-16	83.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi,27YM9@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HSJS2_k127_921387_2	694430.Natoc_4024	1.175e-10	72.0	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,23WU7@183963|Halobacteria	183963|Halobacteria	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
HSJS2_k127_932122_4	1304865.JAGF01000001_gene3018	3.318e-42	160.0	COG0237@1|root,COG0237@2|Bacteria,2IIS6@201174|Actinobacteria	201174|Actinobacteria	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
HSJS2_k127_932122_2	936136.ARRT01000006_gene3849	2.268e-47	187.0	COG0030@1|root,COG0030@2|Bacteria,1R0K7@1224|Proteobacteria,2U8JF@28211|Alphaproteobacteria,4BHK0@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS2_k127_932122_9	497964.CfE428DRAFT_0420	6.266e-22	101.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_932122_8	349163.Acry_1553	4.09e-27	130.0	COG2199@1|root,COG3852@1|root,COG2199@2|Bacteria,COG3852@2|Bacteria,1RGCV@1224|Proteobacteria,2TV94@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
HSJS2_k127_932122_5	1089550.ATTH01000001_gene1576	4.846e-42	160.0	COG0652@1|root,COG0652@2|Bacteria,4PM5K@976|Bacteroidetes,1FJNB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
HSJS2_k127_932122_3	485913.Krac_12126	3.489e-43	173.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi	200795|Chloroflexi	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HSJS2_k127_932122_1	285535.JOEY01000043_gene1195	1.789e-99	339.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria	201174|Actinobacteria	K	epoxide hydrolase	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
HSJS2_k127_932122_0	309801.trd_A0017	4.021e-178	572.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HSJS2_k127_932122_7	1157632.AQWQ01000016_gene3323	1.379e-39	160.0	COG0617@1|root,COG0617@2|Bacteria,2IFKR@201174|Actinobacteria	201174|Actinobacteria	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit
HSJS2_k127_932122_6	243164.DET0005	1.407e-41	158.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,34CRS@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HSJS2_k127_933044_2	448385.sce6421	4.989e-49	182.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
HSJS2_k127_933044_0	398525.KB900701_gene298	2.388e-91	319.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,3JTNQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HSJS2_k127_933044_1	1297742.A176_03357	6.118e-59	217.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YUG7@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD/H associated	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
HSJS2_k127_945408_3	1056816.JAFQ01000004_gene5463	2.015e-06	55.0	COG0183@1|root,COG1024@1|root,COG0183@2|Bacteria,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4FU2F@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	2.3.1.9,4.2.1.149	ko:K00626,ko:K08299	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177,R10675	RC00004,RC00326,RC01095	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ECH_1,Polyketide_cyc2
HSJS2_k127_945408_2	926550.CLDAP_09500	2.338e-11	72.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS2_k127_945408_1	67356.KL575586_gene442	9.416e-14	76.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria	201174|Actinobacteria	IQ	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS2_k127_945408_0	639283.Snov_0285	2.303e-18	86.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TR6T@28211|Alphaproteobacteria,3EYQ5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	MA20_26560	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HSJS2_k127_957323_5	164757.Mjls_4322	1.181e-21	99.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,234SY@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
HSJS2_k127_957323_0	314230.DSM3645_16895	2.413e-137	451.0	COG0189@1|root,COG0189@2|Bacteria,2IYT1@203682|Planctomycetes	203682|Planctomycetes	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification	rimK	-	-	-	-	-	-	-	-	-	-	-	RimK
HSJS2_k127_957323_2	1229172.JQFA01000005_gene119	3.928e-47	177.0	COG4067@1|root,COG4067@2|Bacteria,1G6KI@1117|Cyanobacteria,1HBYC@1150|Oscillatoriales	1117|Cyanobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
HSJS2_k127_957323_6	196162.Noca_2546	2.257e-20	102.0	COG0584@1|root,COG0584@2|Bacteria,2GVYH@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS2_k127_957323_3	349161.Dred_2052	2.474e-28	122.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,261QE@186807|Peptococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HSJS2_k127_957323_8	243164.DET0567	1.015e-13	77.0	COG1837@1|root,COG1837@2|Bacteria,2G7DU@200795|Chloroflexi,34DG8@301297|Dehalococcoidia	301297|Dehalococcoidia	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
HSJS2_k127_957323_4	926569.ANT_16040	1.17e-23	106.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HSJS2_k127_957323_1	986075.CathTA2_1874	1.72e-133	438.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HSJS2_k127_957323_7	172088.AUGA01000048_gene923	3.44e-20	92.0	COG1011@1|root,COG1011@2|Bacteria,1PUN6@1224|Proteobacteria,2TY0G@28211|Alphaproteobacteria,3JU2Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HSJS2_k127_973373_7	288000.BBta_4998	0.0001698	50.0	COG0346@1|root,COG0346@2|Bacteria,1RB65@1224|Proteobacteria,2U7DP@28211|Alphaproteobacteria,3JYA1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	MA20_35640	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
HSJS2_k127_973373_2	1131269.AQVV01000001_gene1432	1.005e-28	123.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung2	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HSJS2_k127_973373_1	479434.Sthe_3197	8.363e-42	163.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YAV@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS2_k127_973373_6	1173027.Mic7113_1823	5.556e-05	55.0	COG5343@1|root,COG5343@2|Bacteria,1G59C@1117|Cyanobacteria,1HAZH@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
HSJS2_k127_973373_0	479434.Sthe_1109	1.477e-60	229.0	COG0628@1|root,COG0628@2|Bacteria,2G712@200795|Chloroflexi,27Z3Y@189775|Thermomicrobia	189775|Thermomicrobia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HSJS2_k127_973373_3	309801.trd_A0182	5.395e-24	109.0	COG0735@1|root,COG0735@2|Bacteria,2G74Y@200795|Chloroflexi,27YIH@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS2_k127_973373_5	262724.TT_C0420	8.467e-11	65.0	COG1116@1|root,COG1116@2|Bacteria,1WJMK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HSJS2_k127_980568_1	1449126.JQKL01000022_gene110	2.011e-131	436.0	COG1008@1|root,COG1008@2|Bacteria,1UHSH@1239|Firmicutes,24AAH@186801|Clostridia	186801|Clostridia	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HSJS2_k127_980568_0	266117.Rxyl_1627	1.828e-142	476.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CPCM@84995|Rubrobacteria	84995|Rubrobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
HSJS2_k127_980568_2	696281.Desru_1815	5.642e-23	101.0	COG0713@1|root,COG0713@2|Bacteria,1V9Z8@1239|Firmicutes,24NKG@186801|Clostridia,262H1@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HSJS2_k127_984251_7	1293054.HSACCH_00068	8.197e-18	85.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WAKN@53433|Halanaerobiales	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HSJS2_k127_984251_1	765420.OSCT_0193	1.107e-77	265.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi,3757R@32061|Chloroflexia	32061|Chloroflexia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HSJS2_k127_984251_6	555079.Toce_0124	4.82e-22	110.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,42GWK@68295|Thermoanaerobacterales	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
HSJS2_k127_984251_4	575605.ACQN01000026_gene822	6.77e-33	129.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae	91061|Bacilli	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
HSJS2_k127_984251_0	552811.Dehly_1094	1.875e-114	374.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi,34CKM@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
HSJS2_k127_984251_5	316274.Haur_4917	5.625e-25	107.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi,375Y1@32061|Chloroflexia	32061|Chloroflexia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
HSJS2_k127_984251_2	643648.Slip_2236	5.511e-54	197.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42JTY@68298|Syntrophomonadaceae	186801|Clostridia	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HSJS2_k127_984251_3	765420.OSCT_0199	1.585e-48	183.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,375C3@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HSJS2_k127_99955_1	1463900.JOIX01000035_gene3787	6.41e-141	457.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HSJS2_k127_99955_0	398525.KB900701_gene2635	8.706e-185	588.0	COG2141@1|root,COG2141@2|Bacteria,1MUVN@1224|Proteobacteria,2TR26@28211|Alphaproteobacteria,3JSBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	MA20_06115	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS2_k127_99955_2	1122237.AUGQ01000002_gene1785	8.299e-51	202.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FM14@85023|Microbacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS2_k127_99955_3	391735.Veis_4965	1.186e-49	183.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2W02P@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
## 2167 queries scanned
## Total time (seconds): 120.78667879104614
## Rate: 17.94 q/s