## Fri Nov 15 02:34:50 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin11/HSJS_3_bin.2.fa -m mmseqs --itype genome -o HSJS_3_bin.2 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HSJS_3_bin.2 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HSJS3_k127_1002021_0	861299.J421_0332	6.374e-90	328.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0332|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1002021_1	234267.Acid_2305	2.371e-24	106.0	COG1695@1|root,COG1695@2|Bacteria,3Y5ZC@57723|Acidobacteria	57723|Acidobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_10056155_12	382464.ABSI01000010_gene3668	8.313e-53	190.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,2ITKY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
HSJS3_k127_10056155_11	382464.ABSI01000010_gene3669	3.451e-74	256.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia,2IU8P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	COX2
HSJS3_k127_10056155_17	382464.ABSI01000010_gene3670	1.373e-40	166.0	COG2863@1|root,COG2863@2|Bacteria,46WZQ@74201|Verrucomicrobia,2IW1M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HSJS3_k127_10056155_22	1499967.BAYZ01000118_gene3298	5.342e-19	90.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
HSJS3_k127_10056155_21	396595.TK90_2294	3.746e-23	106.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1SDVD@1236|Gammaproteobacteria,1WZPY@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
HSJS3_k127_10056155_8	1185876.BN8_00937	1.632e-108	366.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_10056155_23	1346330.M472_21740	0.0003502	49.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1IUCU@117747|Sphingobacteriia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_2,TPR_8
HSJS3_k127_10056155_0	1121104.AQXH01000002_gene612	1.507e-176	587.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IQ09@117747|Sphingobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_10056155_14	926692.AZYG01000018_gene289	2.313e-48	199.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WB2R@53433|Halanaerobiales	186801|Clostridia	S	NMT1-like family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
HSJS3_k127_10056155_1	926561.KB900617_gene1873	9.081e-152	501.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,3WB2B@53433|Halanaerobiales	186801|Clostridia	S	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
HSJS3_k127_10056155_13	649638.Trad_1454	2.126e-50	193.0	COG0696@1|root,COG0696@2|Bacteria,1WIS3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Metalloenzyme	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
HSJS3_k127_10056155_4	340099.Teth39_1067	1.488e-123	422.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
HSJS3_k127_10056155_7	324602.Caur_0861	7.686e-114	385.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HSJS3_k127_10056155_15	861299.J421_6082	1.485e-47	189.0	COG3375@1|root,COG3375@2|Bacteria,1ZUBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_10056155_9	42256.RradSPS_2500	2.503e-79	277.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1611,DUF1611_N,Peptidase_S8
HSJS3_k127_10056155_3	42256.RradSPS_2501	3.132e-125	418.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria,4CQUX@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HSJS3_k127_10056155_10	118163.Ple7327_2337	3.287e-77	269.0	COG1853@1|root,COG1853@2|Bacteria,1G4QZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HSJS3_k127_10056155_6	861299.J421_2523	9.477e-115	400.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
HSJS3_k127_10056155_18	1122614.JHZF01000013_gene3330	2.087e-40	166.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria,2PCYI@252301|Oceanicola	28211|Alphaproteobacteria	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
HSJS3_k127_10056155_2	469371.Tbis_1138	2.182e-142	476.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4E05Y@85010|Pseudonocardiales	201174|Actinobacteria	C	Glycolate oxidase subunit GlcD	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
HSJS3_k127_10056155_16	1122963.AUHB01000001_gene369	2.406e-43	171.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,36Y4U@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	MA20_07390	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HSJS3_k127_10056155_20	580327.Tthe_2001	8.324e-31	126.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,24J9S@186801|Clostridia,42GF6@68295|Thermoanaerobacterales	186801|Clostridia	T	pfam gaf	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
HSJS3_k127_10056155_5	383372.Rcas_0232	1.98e-122	403.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HSJS3_k127_10056155_19	574087.Acear_1823	2.895e-31	128.0	COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,24NG5@186801|Clostridia,3WBVZ@53433|Halanaerobiales	186801|Clostridia	S	PFAM FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
HSJS3_k127_10135542_9	485915.Dret_1750	2.062e-27	113.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
HSJS3_k127_10135542_5	109760.SPPG_04804T0	9.267e-100	336.0	COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi	4751|Fungi	Q	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_10135542_10	1121930.AQXG01000006_gene821	0.0002724	53.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
HSJS3_k127_10135542_6	1379270.AUXF01000005_gene644	8.981e-68	250.0	28NKC@1|root,2ZBM7@2|Bacteria,1ZUHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_10135542_2	234267.Acid_3236	2.757e-198	638.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
HSJS3_k127_10135542_4	1156919.QWC_03453	4.811e-107	359.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria	28216|Betaproteobacteria	EQ	PFAM peptidase S58, DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
HSJS3_k127_10135542_0	765912.Thimo_0244	0.0	1103.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1WXBR@135613|Chromatiales	135613|Chromatiales	C	Isocitrate dehydrogenase NADP-dependent, monomeric type	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
HSJS3_k127_10135542_3	713586.KB900536_gene258	5.605e-177	566.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
HSJS3_k127_10135542_8	1121930.AQXG01000009_gene289	1.69e-55	206.0	COG3544@1|root,COG3544@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
HSJS3_k127_10135542_1	1121930.AQXG01000009_gene290	3.872e-289	905.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
HSJS3_k127_10135542_7	1089550.ATTH01000001_gene571	1.959e-66	234.0	COG1960@1|root,COG3793@1|root,COG1960@2|Bacteria,COG3793@2|Bacteria,4NF87@976|Bacteroidetes,1FJZY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IP	Acyl-CoA oxidase	-	-	1.3.3.6	ko:K00232	ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146	M00087,M00113	R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_10149240_6	517418.Ctha_0048	1.918e-144	485.0	COG1629@1|root,COG4771@2|Bacteria,1FFAD@1090|Chlorobi	1090|Chlorobi	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HSJS3_k127_10149240_15	518766.Rmar_2730	1.03e-26	114.0	COG4270@1|root,COG4270@2|Bacteria,4NVXH@976|Bacteroidetes	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HSJS3_k127_10149240_3	102232.GLO73106DRAFT_00000590	3.97e-172	561.0	COG1166@1|root,COG1166@2|Bacteria,1G1C4@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
HSJS3_k127_10149240_8	1379270.AUXF01000002_gene1163	1.349e-115	385.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	fimA	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
HSJS3_k127_10149240_14	1040989.AWZU01000005_gene177	7.685e-39	150.0	COG4430@1|root,COG4430@2|Bacteria,1QZAG@1224|Proteobacteria,2TZCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_10149240_0	1089550.ATTH01000001_gene1477	6.943e-198	643.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
HSJS3_k127_10149240_4	251221.35214831	3.08e-159	517.0	COG2141@1|root,COG2141@2|Bacteria,1G134@1117|Cyanobacteria	1117|Cyanobacteria	C	Luciferase-like monooxygenase	-	-	1.14.14.35,1.14.14.5	ko:K04091,ko:K17228	ko00920,map00920	-	R07210,R10203,R10206	RC01779,RC02556,RC03080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
HSJS3_k127_10149240_7	1210884.HG799465_gene11589	3.866e-124	407.0	COG0189@1|root,COG0189@2|Bacteria,2J20G@203682|Planctomycetes	203682|Planctomycetes	HJ	RimK-like ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
HSJS3_k127_10149240_9	1123508.JH636448_gene7625	2.805e-81	286.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_10149240_1	1122604.JONR01000015_gene114	4.034e-195	621.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1X4K6@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HSJS3_k127_10149240_17	543526.Htur_3342	1.17e-06	59.0	COG1305@1|root,COG1404@1|root,arCOG00702@2157|Archaea,arCOG02486@2157|Archaea,2XTGN@28890|Euryarchaeota,23TTV@183963|Halobacteria	183963|Halobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_S8
HSJS3_k127_10149240_5	263358.VAB18032_04695	2.151e-153	489.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4D8QA@85008|Micromonosporales	201174|Actinobacteria	P	Sulfurtransferase	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HSJS3_k127_10149240_13	649638.Trad_0782	6.376e-45	168.0	COG2166@1|root,COG2166@2|Bacteria,1WK00@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
HSJS3_k127_10149240_10	1121930.AQXG01000001_gene1299	2.685e-70	252.0	COG3391@1|root,COG3391@2|Bacteria,4PJH2@976|Bacteroidetes,1IZRD@117747|Sphingobacteriia	976|Bacteroidetes	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
HSJS3_k127_10149240_11	1496688.ER33_03045	1.803e-59	218.0	COG0500@1|root,COG2226@2|Bacteria,1G60J@1117|Cyanobacteria,22T7D@167375|Cyanobium	1117|Cyanobacteria	Q	SAM (And some other nucleotide) binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS3_k127_10149240_2	861299.J421_1447	6.433e-192	615.0	COG4108@1|root,COG4108@2|Bacteria,1ZSMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
HSJS3_k127_10149240_12	1122614.JHZF01000013_gene3781	3.192e-50	182.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2U79E@28211|Alphaproteobacteria,2PE7C@252301|Oceanicola	28211|Alphaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
HSJS3_k127_10354146_5	861299.J421_3595	1.222e-92	317.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HSJS3_k127_10354146_2	861299.J421_3597	1.943e-136	443.0	COG0022@1|root,COG0022@2|Bacteria,1ZT89@142182|Gemmatimonadetes	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HSJS3_k127_10354146_16	497964.CfE428DRAFT_6473	8.504e-20	102.0	COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HSJS3_k127_10354146_17	1379270.AUXF01000006_gene215	1.122e-19	93.0	COG1314@1|root,COG1314@2|Bacteria,1ZTZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HSJS3_k127_10354146_6	1267533.KB906737_gene1553	4.058e-74	258.0	COG0149@1|root,COG0149@2|Bacteria,3Y2YS@57723|Acidobacteria,2JIK9@204432|Acidobacteriia	204432|Acidobacteriia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HSJS3_k127_10354146_3	861299.J421_3309	1.501e-129	426.0	COG0126@1|root,COG0126@2|Bacteria,1ZT1B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HSJS3_k127_10354146_0	1121929.KB898663_gene888	1.194e-145	477.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,47059@74385|Gracilibacillus	91061|Bacilli	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HSJS3_k127_10354146_15	861299.J421_3311	7.208e-26	118.0	COG1040@1|root,COG1040@2|Bacteria,1ZTS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
HSJS3_k127_10354146_10	671143.DAMO_3014	1.872e-49	189.0	COG0169@1|root,COG0169@2|Bacteria,2NPR3@2323|unclassified Bacteria	2|Bacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HSJS3_k127_10354146_13	861299.J421_3313	2.05e-30	132.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HSJS3_k127_10354146_12	861299.J421_3314	1.417e-42	172.0	COG0009@1|root,COG0009@2|Bacteria,1ZT3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
HSJS3_k127_10354146_11	292459.STH3123	2.627e-45	174.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
HSJS3_k127_10354146_1	555079.Toce_2251	2.671e-145	475.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,42FJ3@68295|Thermoanaerobacterales	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HSJS3_k127_10354146_8	1366050.N234_11775	4.612e-57	213.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,1K1QM@119060|Burkholderiaceae	28216|Betaproteobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HSJS3_k127_10354146_4	861299.J421_3319	2.381e-119	398.0	COG0452@1|root,COG0452@2|Bacteria,1ZV19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HSJS3_k127_10354146_18	1379270.AUXF01000006_gene203	9.321e-15	76.0	28VAR@1|root,2ZHDJ@2|Bacteria,1ZU25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
HSJS3_k127_10354146_9	1121440.AUMA01000007_gene1250	2.211e-53	196.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2MB44@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HSJS3_k127_10354146_7	379066.GAU_1690	1.11e-64	232.0	COG1561@1|root,COG1561@2|Bacteria,1ZT99@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HSJS3_k127_10354146_19	1379270.AUXF01000006_gene200	1.673e-10	74.0	COG4206@1|root,COG4206@2|Bacteria,1ZT1E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
HSJS3_k127_10354146_14	1232410.KI421427_gene1286	6.214e-30	120.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HSJS3_k127_10447423_9	867902.Ornrh_1857	2.586e-44	163.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1HXVA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
HSJS3_k127_10447423_2	1379270.AUXF01000006_gene160	7.222e-105	358.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_10447423_4	1122180.Lokhon_01456	1.147e-78	271.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,2P8KN@245186|Loktanella	28211|Alphaproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HSJS3_k127_10447423_7	379066.GAU_1729	4.192e-67	237.0	COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HSJS3_k127_10447423_3	861299.J421_3367	5.566e-98	331.0	COG0547@1|root,COG0547@2|Bacteria,1ZTDS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
HSJS3_k127_10447423_5	379066.GAU_1726	8.34e-76	259.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HSJS3_k127_10447423_8	575540.Isop_3670	1.659e-65	243.0	COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HSJS3_k127_10447423_11	338966.Ppro_1292	5.951e-27	121.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HSJS3_k127_10447423_0	1266909.AUAG01000021_gene344	2.115e-170	543.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS3_k127_10447423_6	1379270.AUXF01000006_gene168	1.303e-71	263.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
HSJS3_k127_10447423_1	1379270.AUXF01000006_gene169	1.449e-116	396.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
HSJS3_k127_10447423_10	1121035.AUCH01000014_gene2426	1.201e-41	166.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,2KV5S@206389|Rhodocyclales	206389|Rhodocyclales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HSJS3_k127_1091019_0	713587.THITH_03495	3.173e-218	692.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1WX9G@135613|Chromatiales	135613|Chromatiales	C	PFAM Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
HSJS3_k127_1091019_1	1379270.AUXF01000001_gene2562	4.512e-109	370.0	COG0513@1|root,COG0513@2|Bacteria,1ZSX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JKL	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HSJS3_k127_1091019_5	502025.Hoch_3589	5.403e-48	177.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42RY9@68525|delta/epsilon subdivisions,2WW61@28221|Deltaproteobacteria,2Z2RX@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HSJS3_k127_1091019_4	1124780.ANNU01000058_gene888	2.167e-61	223.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,47K5K@768503|Cytophagia	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
HSJS3_k127_1091019_8	1121028.ARQE01000007_gene3916	4.218e-21	107.0	COG0454@1|root,COG0456@2|Bacteria,1N1SW@1224|Proteobacteria,2UE13@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HSJS3_k127_1091019_2	1121440.AUMA01000016_gene179	9.41e-89	308.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2M8HV@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_1091019_9	1112217.PPL19_22769	7.956e-17	91.0	COG2761@1|root,COG2761@2|Bacteria,1RIE0@1224|Proteobacteria	1224|Proteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
HSJS3_k127_1091019_6	1146883.BLASA_4949	2.456e-47	189.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HSJS3_k127_1091019_7	1118235.CAJH01000057_gene3243	1.276e-24	107.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HSJS3_k127_1091019_3	555088.DealDRAFT_2272	8.69e-70	249.0	COG1226@1|root,COG1226@2|Bacteria,1V2CY@1239|Firmicutes,24DT6@186801|Clostridia,42KNC@68298|Syntrophomonadaceae	186801|Clostridia	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
HSJS3_k127_1172337_8	497965.Cyan7822_1303	6.77e-33	129.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,3KI4G@43988|Cyanothece	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HSJS3_k127_1172337_7	1379270.AUXF01000003_gene3650	1.139e-57	214.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1ZSX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
HSJS3_k127_1172337_10	406327.Mevan_1451	0.0003464	51.0	COG1605@1|root,arCOG02098@2157|Archaea,2XYXR@28890|Euryarchaeota,23R8E@183939|Methanococci	183939|Methanococci	E	PFAM Chorismate mutase	aroQ	GO:0003674,GO:0003824,GO:0004664,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046983,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
HSJS3_k127_1172337_6	1210908.HSB1_00800	3.381e-68	243.0	COG1024@1|root,arCOG00239@2157|Archaea,2XTF0@28890|Euryarchaeota,23SMM@183963|Halobacteria	183963|Halobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS3_k127_1172337_4	391625.PPSIR1_25066	1.455e-102	344.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HSJS3_k127_1172337_1	485913.Krac_12473	5.644e-154	496.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
HSJS3_k127_1172337_3	1254432.SCE1572_35290	1.053e-109	360.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,43AB6@68525|delta/epsilon subdivisions,2X259@28221|Deltaproteobacteria,2YZEP@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS3_k127_1172337_5	937777.Deipe_2634	6.336e-90	313.0	COG1030@1|root,COG1030@2|Bacteria,1WIAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
HSJS3_k127_1172337_2	1121859.KB890741_gene3739	4.495e-131	425.0	COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia	976|Bacteroidetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
HSJS3_k127_1172337_0	1382304.JNIL01000001_gene3056	0.0	1192.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,2793N@186823|Alicyclobacillaceae	91061|Bacilli	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06730	Aconitase,Aconitase_C
HSJS3_k127_1213199_4	644282.Deba_1918	8.61e-51	184.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HSJS3_k127_1213199_7	861299.J421_2877	1.41e-24	108.0	COG4980@1|root,COG4980@2|Bacteria,1ZU46@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
HSJS3_k127_1213199_6	861299.J421_2878	3.241e-34	143.0	COG1295@1|root,COG1295@2|Bacteria,1ZTHX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HSJS3_k127_1213199_5	1303518.CCALI_02029	4.67e-46	182.0	COG0691@1|root,COG0691@2|Bacteria	2|Bacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HSJS3_k127_1213199_3	861299.J421_3583	2.641e-54	207.0	COG0860@1|root,COG0860@2|Bacteria,1ZSUX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HSJS3_k127_1213199_1	861299.J421_3582	1.801e-79	282.0	COG0167@1|root,COG0167@2|Bacteria,1ZT86@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HSJS3_k127_1213199_2	1111454.HMPREF1250_0237	3.062e-58	224.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4H1VK@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HSJS3_k127_1213199_0	861299.J421_2757	2.739e-153	497.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
HSJS3_k127_1213199_10	1121447.JONL01000001_gene735	2.231e-06	52.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1213199_8	631362.Thi970DRAFT_01941	5.392e-15	77.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1WWIK@135613|Chromatiales	135613|Chromatiales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HSJS3_k127_1370392_1	68223.JNZY01000001_gene5559	2.535e-38	152.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HSJS3_k127_1370392_0	861299.J421_2808	3.309e-98	330.0	COG0492@1|root,COG0492@2|Bacteria,1ZSW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
HSJS3_k127_1370392_6	1191523.MROS_1889	3.698e-05	55.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	porV	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1370392_5	1278073.MYSTI_00752	6.949e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1Q2MK@1224|Proteobacteria,43886@68525|delta/epsilon subdivisions,2X3HX@28221|Deltaproteobacteria,2YW6E@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1370392_4	1379270.AUXF01000007_gene972	9.189e-16	80.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_1370392_3	1379270.AUXF01000007_gene972	1.647e-26	112.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_1370392_2	234267.Acid_1951	3.604e-38	150.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
HSJS3_k127_1413487_3	861299.J421_3390	6.715e-64	226.0	COG0442@1|root,COG0442@2|Bacteria,1ZT48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HSJS3_k127_1413487_0	1161401.ASJA01000025_gene214	1.447e-207	657.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria,43X30@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HSJS3_k127_1413487_4	391625.PPSIR1_05718	1.668e-44	165.0	COG0251@1|root,COG0251@2|Bacteria,1RES6@1224|Proteobacteria,435VN@68525|delta/epsilon subdivisions,2X0B9@28221|Deltaproteobacteria,2Z1FV@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HSJS3_k127_1413487_1	756272.Plabr_0269	9.855e-108	365.0	COG1092@1|root,COG1092@2|Bacteria,2IWV1@203682|Planctomycetes	203682|Planctomycetes	J	(SAM)-dependent	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HSJS3_k127_1413487_2	290397.Adeh_0985	1.664e-65	239.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HSJS3_k127_1422235_14	861299.J421_2930	7.457e-59	211.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HSJS3_k127_1422235_3	861299.J421_2927	2.961e-138	458.0	COG0621@1|root,COG0621@2|Bacteria,1ZT70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
HSJS3_k127_1422235_27	861299.J421_2941	1.501e-23	117.0	COG2834@1|root,COG2834@2|Bacteria,1ZTXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
HSJS3_k127_1422235_1	1379270.AUXF01000006_gene38	1.563e-187	612.0	COG1674@1|root,COG1674@2|Bacteria,1ZSPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HSJS3_k127_1422235_20	1379698.RBG1_1C00001G0649	2.217e-39	158.0	COG2045@1|root,COG2045@2|Bacteria,2NPF1@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ComB family	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
HSJS3_k127_1422235_0	861299.J421_3533	8.19e-204	646.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HSJS3_k127_1422235_21	166314.Syncc8109_0034	1.56e-35	143.0	COG0511@1|root,COG0511@2|Bacteria,1G6MY@1117|Cyanobacteria,1GZ7K@1129|Synechococcus	1117|Cyanobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HSJS3_k127_1422235_11	518766.Rmar_0673	4.745e-61	216.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1FJ6E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HSJS3_k127_1422235_17	1125863.JAFN01000001_gene2274	4.643e-46	177.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
HSJS3_k127_1422235_37	443143.GM18_1392	2.175e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1NEMW@1224|Proteobacteria,42WBX@68525|delta/epsilon subdivisions,2WRAD@28221|Deltaproteobacteria,43VAR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_8
HSJS3_k127_1422235_7	379066.GAU_1929	6.255e-89	326.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
HSJS3_k127_1422235_31	1089550.ATTH01000001_gene142	4.499e-17	86.0	COG1826@1|root,COG1826@2|Bacteria,4PETH@976|Bacteroidetes,1FJKH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HSJS3_k127_1422235_35	379066.GAU_1931	4.871e-09	61.0	2FH8C@1|root,3492Q@2|Bacteria,1ZTXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
HSJS3_k127_1422235_4	379066.GAU_1932	1.356e-110	371.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HSJS3_k127_1422235_16	861299.J421_3542	7.694e-48	192.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
HSJS3_k127_1422235_13	1121468.AUBR01000045_gene1801	3.246e-59	217.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,42EU0@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
HSJS3_k127_1422235_38	1123326.JFBL01000014_gene259	7.605e-06	58.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
HSJS3_k127_1422235_8	861299.J421_3547	1.479e-69	268.0	COG1452@1|root,COG1452@2|Bacteria,1ZT14@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1422235_15	861299.J421_3548	4.004e-55	205.0	COG0805@1|root,COG0805@2|Bacteria,1ZTHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HSJS3_k127_1422235_18	429009.Adeg_1549	3.308e-42	160.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,42GHP@68295|Thermoanaerobacterales	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HSJS3_k127_1422235_33	1294143.H681_17770	1.923e-15	87.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
HSJS3_k127_1422235_23	1125863.JAFN01000001_gene3050	1.193e-31	134.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
HSJS3_k127_1422235_10	1379270.AUXF01000006_gene17	2.817e-65	243.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
HSJS3_k127_1422235_32	861299.J421_3552	5.819e-16	88.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
HSJS3_k127_1422235_26	1122613.ATUP01000001_gene943	1.766e-25	111.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,43YA5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	U	ExbD TolR family transport energizing protein	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
HSJS3_k127_1422235_24	1232410.KI421422_gene2007	2.826e-29	129.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,43S1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
HSJS3_k127_1422235_6	1121468.AUBR01000031_gene1289	4.822e-101	338.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,42F1C@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HSJS3_k127_1422235_36	1112217.PPL19_08926	1.251e-08	68.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	protein containing LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	LysM
HSJS3_k127_1422235_9	861299.J421_3564	7.957e-68	246.0	COG2003@1|root,COG2003@2|Bacteria,1ZTFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HSJS3_k127_1422235_22	273068.TTE0537	5.685e-32	135.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
HSJS3_k127_1422235_30	1232410.KI421418_gene2270	6.553e-18	93.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,43UNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HSJS3_k127_1422235_25	861299.J421_3560	1.703e-27	118.0	COG0802@1|root,COG0802@2|Bacteria,1ZTY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
HSJS3_k127_1422235_19	1120973.AQXL01000135_gene1478	8.096e-40	163.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,278EE@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HSJS3_k127_1422235_28	1089550.ATTH01000001_gene1767	4.814e-20	99.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1FITY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Outer membrane lipoprotein	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
HSJS3_k127_1422235_39	765910.MARPU_09170	0.0001656	53.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WXP6@135613|Chromatiales	135613|Chromatiales	O	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
HSJS3_k127_1422235_34	1040989.AWZU01000004_gene7073	7.233e-11	73.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,3K2NJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_2,TPR_8
HSJS3_k127_1422235_2	861299.J421_0145	2.883e-148	477.0	COG0451@1|root,COG0451@2|Bacteria,1ZUJJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HSJS3_k127_1422235_12	215803.DB30_3219	1.019e-60	214.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2YTZC@29|Myxococcales	28221|Deltaproteobacteria	C	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HSJS3_k127_1422235_5	861299.J421_0144	2.542e-107	356.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HSJS3_k127_1422235_40	316067.Geob_0430	0.0004317	43.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HSJS3_k127_1422856_1	379066.GAU_2314	1.694e-175	558.0	COG2960@1|root,COG2960@2|Bacteria,1ZURC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
HSJS3_k127_1422856_0	379066.GAU_2315	1.166e-278	880.0	COG0551@1|root,COG0551@2|Bacteria,1ZUEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
HSJS3_k127_1422856_5	379066.GAU_0126	3.018e-15	89.0	2EY2H@1|root,33RBE@2|Bacteria,1ZTHK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1422856_2	45151.EDU50588	1.009e-87	301.0	COG4242@1|root,2SDNU@2759|Eukaryota,39XTH@33154|Opisthokonta,3P089@4751|Fungi,3QN1Z@4890|Ascomycota,203QM@147541|Dothideomycetes,4KH07@92860|Pleosporales	4751|Fungi	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
HSJS3_k127_1422856_3	1460635.JCM19038_1757	6.936e-87	305.0	COG0591@1|root,COG0591@2|Bacteria,1TRYH@1239|Firmicutes,4HE2W@91061|Bacilli	91061|Bacilli	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HSJS3_k127_1422856_4	797304.Natgr_0212	1.347e-36	143.0	COG0318@1|root,arCOG00856@2157|Archaea,2XST5@28890|Euryarchaeota,23SBA@183963|Halobacteria	183963|Halobacteria	I	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
HSJS3_k127_1430244_11	1121946.AUAX01000023_gene4154	4.101e-11	66.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4DIDG@85008|Micromonosporales	201174|Actinobacteria	S	Homoserine dehydrogenase, NAD binding domain	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HSJS3_k127_1430244_9	196162.Noca_0078	4.395e-55	203.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4DPRR@85009|Propionibacteriales	201174|Actinobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K18009	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS3_k127_1430244_0	404589.Anae109_3076	2.582e-148	501.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,42NVR@68525|delta/epsilon subdivisions,2WM9A@28221|Deltaproteobacteria,2YU0T@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
HSJS3_k127_1430244_1	1173026.Glo7428_3203	2.749e-130	427.0	COG4608@1|root,COG4608@2|Bacteria,1G1Q0@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HSJS3_k127_1430244_2	489825.LYNGBM3L_32450	9.504e-119	390.0	COG0444@1|root,COG0444@2|Bacteria,1G1NU@1117|Cyanobacteria,1HA9I@1150|Oscillatoriales	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HSJS3_k127_1430244_7	1121378.KB899737_gene3941	6.588e-90	305.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	MA20_01210	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HSJS3_k127_1430244_5	1121378.KB899737_gene3940	1.24e-99	334.0	COG0601@1|root,COG0601@2|Bacteria,1WIUD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HSJS3_k127_1430244_10	1379270.AUXF01000004_gene2933	1.06e-45	175.0	COG2755@1|root,COG2755@2|Bacteria,1ZU6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1430244_6	1379270.AUXF01000005_gene754	5.77e-91	325.0	COG0747@1|root,COG0747@2|Bacteria,1ZUDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HSJS3_k127_1430244_3	1379270.AUXF01000005_gene755	8.686e-113	398.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
HSJS3_k127_1430244_4	566466.NOR53_1394	2.75e-110	366.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1JAP5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS3_k127_1481211_2	1379270.AUXF01000001_gene2140	1.592e-174	561.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
HSJS3_k127_1481211_5	1379270.AUXF01000001_gene2140	5.597e-93	311.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
HSJS3_k127_1481211_0	1121930.AQXG01000012_gene3213	0.0	1296.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,1IVI6@117747|Sphingobacteriia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
HSJS3_k127_1481211_3	1379270.AUXF01000002_gene1163	2.073e-110	368.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	fimA	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
HSJS3_k127_1481211_7	1379270.AUXF01000002_gene1802	2.145e-18	96.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1481211_4	319003.Bra1253DRAFT_06315	3.775e-103	351.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,2TUF8@28211|Alphaproteobacteria,3JS8B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HSJS3_k127_1481211_8	861299.J421_3049	7.24e-17	85.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
HSJS3_k127_1481211_10	864702.OsccyDRAFT_2787	6.648e-09	65.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1HB2G@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
HSJS3_k127_1481211_6	109871.XP_006677605.1	7.288e-22	106.0	COG0705@1|root,KOG2980@2759|Eukaryota,3A5ZS@33154|Opisthokonta	33154|Opisthokonta	T	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
HSJS3_k127_1481211_9	309807.SRU_1452	1.554e-12	78.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1481211_1	518766.Rmar_2667	1.52e-189	610.0	COG0475@1|root,COG0569@1|root,COG1762@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,4NFPE@976|Bacteroidetes	976|Bacteroidetes	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
HSJS3_k127_1486396_0	231434.JQJH01000001_gene1931	0.0	2045.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,3NAF8@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HSJS3_k127_1486396_2	243233.MCA2040	1.687e-225	708.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XE4Y@135618|Methylococcales	135618|Methylococcales	C	Glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HSJS3_k127_1486396_4	247633.GP2143_12761	7.398e-140	458.0	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,1RMWH@1236|Gammaproteobacteria,1J6IE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_1486396_5	1121875.KB907548_gene1381	9.835e-53	203.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_1486396_1	1089550.ATTH01000001_gene1477	8.045e-226	726.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
HSJS3_k127_1486396_3	1121930.AQXG01000001_gene1300	3.28e-188	608.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1IYME@117747|Sphingobacteriia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
HSJS3_k127_1486396_6	864073.HFRIS_000085	4.539e-49	188.0	COG5495@1|root,COG5495@2|Bacteria,1RDUW@1224|Proteobacteria,2VRC5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	nadp oxidoreductase, coenzyme f420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HSJS3_k127_1494085_7	861299.J421_3262	2.401e-93	314.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HSJS3_k127_1494085_11	1379270.AUXF01000002_gene1444	9.063e-79	284.0	COG0793@1|root,COG0793@2|Bacteria,1ZT92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HSJS3_k127_1494085_2	316274.Haur_4289	5.536e-179	608.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G7JV@200795|Chloroflexi,375WH@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
HSJS3_k127_1494085_16	1188256.BASI01000002_gene3684	6.371e-66	229.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,3FD26@34008|Rhodovulum	28211|Alphaproteobacteria	EH	Peptidase C26	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HSJS3_k127_1494085_15	861299.J421_3258	4.028e-67	237.0	COG1212@1|root,COG1212@2|Bacteria,1ZSRD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
HSJS3_k127_1494085_0	861299.J421_3257	5.688e-251	792.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HSJS3_k127_1494085_9	1379270.AUXF01000006_gene266	1.287e-89	304.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
HSJS3_k127_1494085_17	379066.GAU_1622	3.348e-48	189.0	COG1778@1|root,COG1778@2|Bacteria,1ZTTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
HSJS3_k127_1494085_6	861299.J421_3254	1.652e-98	338.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1ZT08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
HSJS3_k127_1494085_24	861299.J421_3253	2.908e-17	94.0	2DWX3@1|root,342B9@2|Bacteria,1ZTXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
HSJS3_k127_1494085_22	379066.GAU_1619	6.864e-27	126.0	2F01D@1|root,33T57@2|Bacteria,1ZTGK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1494085_4	1379270.AUXF01000006_gene271	2.417e-111	368.0	COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
HSJS3_k127_1494085_3	861299.J421_3250	9.376e-177	571.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HSJS3_k127_1494085_13	1379698.RBG1_1C00001G1315	2.515e-72	256.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HSJS3_k127_1494085_5	646529.Desaci_4634	8.122e-106	357.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,26040@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
HSJS3_k127_1494085_20	404589.Anae109_1425	7.779e-32	139.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2Z144@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_1494085_12	1379698.RBG1_1C00001G0995	1.335e-73	279.0	COG5617@1|root,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria	2|Bacteria	E	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HSJS3_k127_1494085_23	1379270.AUXF01000006_gene275	1.648e-20	105.0	COG0392@1|root,COG0392@2|Bacteria,1ZTX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HSJS3_k127_1494085_8	379066.GAU_1612	8.833e-91	307.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HSJS3_k127_1494085_25	69014.TK2241	1.751e-13	81.0	COG0500@1|root,arCOG01790@2157|Archaea,2XWZ1@28890|Euryarchaeota,24335@183968|Thermococci	183968|Thermococci	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS3_k127_1494085_27	1121106.JQKB01000045_gene2995	3.969e-10	71.0	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,2UD6M@28211|Alphaproteobacteria,2JXEU@204441|Rhodospirillales	204441|Rhodospirillales	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
HSJS3_k127_1494085_18	187272.Mlg_0175	6.482e-48	179.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales	135613|Chromatiales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
HSJS3_k127_1494085_28	1123392.AQWL01000004_gene2699	5.615e-05	53.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,1KRTK@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
HSJS3_k127_1494085_19	1128421.JAGA01000001_gene2006	4.344e-42	159.0	COG2363@1|root,COG2363@2|Bacteria,2NRMS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
HSJS3_k127_1494085_14	861299.J421_4497	6.125e-72	258.0	COG0846@1|root,COG0846@2|Bacteria,1ZTRK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HSJS3_k127_1494085_10	861299.J421_1115	2.126e-82	285.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1494085_1	379066.GAU_3235	2.554e-195	635.0	COG2091@1|root,COG2091@2|Bacteria,1ZUGF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1494085_21	756272.Plabr_1679	2.462e-27	113.0	2FJRH@1|root,34BEB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1496432_1	631454.N177_2186	5.746e-294	907.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2TSXP@28211|Alphaproteobacteria,1JPRD@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Urease alpha-subunit, N-terminal domain	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
HSJS3_k127_1496432_9	388399.SSE37_22075	7.222e-48	173.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2U9T4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
HSJS3_k127_1496432_7	1041139.KB902680_gene1522	1.363e-54	192.0	COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,2U947@28211|Alphaproteobacteria,4BF8W@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
HSJS3_k127_1496432_5	631454.N177_2184	2.742e-64	232.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2U57R@28211|Alphaproteobacteria,1JPRV@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	UreD urease accessory protein	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
HSJS3_k127_1496432_2	861299.J421_2989	1.073e-172	558.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HSJS3_k127_1496432_6	518766.Rmar_1872	1.276e-55	211.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1FITI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
HSJS3_k127_1496432_8	1121957.ATVL01000008_gene4703	3.062e-54	198.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_1496432_11	1379270.AUXF01000003_gene3855	7.309e-38	145.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
HSJS3_k127_1496432_10	861299.J421_2991	1.493e-46	175.0	COG0241@1|root,COG0241@2|Bacteria,1ZTT8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
HSJS3_k127_1496432_3	1121430.JMLG01000005_gene718	2.315e-117	399.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
HSJS3_k127_1496432_12	1379270.AUXF01000005_gene588	1.399e-29	134.0	COG2372@1|root,COG2372@2|Bacteria,1ZTUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
HSJS3_k127_1496432_0	861299.J421_2994	1.317e-295	934.0	COG0525@1|root,COG0525@2|Bacteria,1ZSXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HSJS3_k127_1496432_4	861299.J421_3701	5.89e-107	353.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_1503903_10	861299.J421_3337	8.357e-32	127.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HSJS3_k127_1503903_5	867903.ThesuDRAFT_00656	5.368e-111	377.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
HSJS3_k127_1503903_2	379066.GAU_1701	5.436e-172	548.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_1503903_6	1235279.C772_01362	1.136e-94	329.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,26DIU@186818|Planococcaceae	91061|Bacilli	L	DNA helicase	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HSJS3_k127_1503903_8	1313301.AUGC01000015_gene1856	1.2e-53	202.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS3_k127_1503903_9	880073.Calab_1746	1.352e-39	159.0	2CIU6@1|root,32S8H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1503903_1	861299.J421_3345	5.136e-197	637.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
HSJS3_k127_1503903_0	379066.GAU_1707	1.512e-231	729.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HSJS3_k127_1503903_7	861299.J421_3347	1.426e-59	216.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
HSJS3_k127_1503903_4	1379270.AUXF01000004_gene3298	1.104e-121	416.0	COG4206@1|root,COG4206@2|Bacteria,1ZUAE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
HSJS3_k127_1503903_3	861299.J421_3349	3.448e-156	499.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HSJS3_k127_1508911_5	1120965.AUBV01000008_gene1997	2.031e-17	83.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,47R71@768503|Cytophagia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
HSJS3_k127_1508911_7	1254432.SCE1572_38210	9.804e-14	78.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,4383R@68525|delta/epsilon subdivisions,2X3DQ@28221|Deltaproteobacteria,2YVM1@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_1508911_8	675635.Psed_5888	0.0001803	47.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria	675635.Psed_5888|-	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1508911_6	861299.J421_0958	4.548e-17	84.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_1508911_0	1297742.A176_04929	1.115e-123	433.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_1508911_4	1335757.SPICUR_00755	2.062e-18	96.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,1RNS3@1236|Gammaproteobacteria,1WY2Y@135613|Chromatiales	135613|Chromatiales	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HSJS3_k127_1508911_1	1192034.CAP_4260	5.008e-90	306.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
HSJS3_k127_1508911_3	1296415.JACC01000001_gene3451	2e-55	205.0	COG0657@1|root,COG0657@2|Bacteria,4NGAF@976|Bacteroidetes,1HZ5F@117743|Flavobacteriia,2YIAD@290174|Aquimarina	976|Bacteroidetes	I	Protein of unknown function (DUF1460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460
HSJS3_k127_1508911_2	391625.PPSIR1_18075	2.747e-58	206.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HSJS3_k127_1541482_2	268739.Nmlp_1471	3.568e-13	70.0	COG0604@1|root,arCOG01458@2157|Archaea,2XU0Q@28890|Euryarchaeota,23SPC@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_1541482_1	767817.Desgi_2508	2.794e-38	147.0	COG1694@1|root,COG4198@1|root,COG1694@2|Bacteria,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HSJS3_k127_1541482_0	1382306.JNIM01000001_gene1964	4.429e-100	337.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	ycbU	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_1565217_4	1047013.AQSP01000079_gene2041	1.986e-113	391.0	COG0841@1|root,COG0841@2|Bacteria,2NQI6@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	mdtC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HSJS3_k127_1565217_2	1047013.AQSP01000102_gene979	2.649e-151	520.0	COG0841@1|root,COG0841@2|Bacteria,2NQF8@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HSJS3_k127_1565217_6	861299.J421_1377	5.129e-40	162.0	2EQJ9@1|root,33I5A@2|Bacteria,1ZTSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1565217_7	861299.J421_1376	3.545e-39	166.0	2AER0@1|root,314MK@2|Bacteria,1ZTTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1565217_0	926550.CLDAP_17390	4.505e-266	842.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,2G827@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HSJS3_k127_1565217_3	644966.Tmar_0077	7.898e-124	418.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HSJS3_k127_1565217_9	861299.J421_2985	4.173e-30	128.0	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,LexA_DNA_bind,Peptidase_S24
HSJS3_k127_1565217_5	861299.J421_3139	1.569e-52	193.0	COG0590@1|root,COG0590@2|Bacteria,1ZTW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
HSJS3_k127_1565217_8	521045.Kole_1995	2.84e-37	160.0	COG1649@1|root,COG1649@2|Bacteria,2GCSB@200918|Thermotogae	200918|Thermotogae	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HSJS3_k127_1565217_1	1089550.ATTH01000001_gene2547	2.226e-157	518.0	COG1757@1|root,COG1757@2|Bacteria,4NHP9@976|Bacteroidetes,1FIXG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
HSJS3_k127_1572857_5	234267.Acid_7937	9.949e-96	323.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_1572857_4	215803.DB30_3562	2.509e-110	376.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42U6K@68525|delta/epsilon subdivisions,2WQ4K@28221|Deltaproteobacteria,2YZCG@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
HSJS3_k127_1572857_1	215803.DB30_3561	4.623e-141	461.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_1572857_7	1379270.AUXF01000001_gene2411	4.509e-14	83.0	COG0265@1|root,COG0265@2|Bacteria,1ZU1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2
HSJS3_k127_1572857_9	1379270.AUXF01000001_gene2410	6.779e-05	55.0	2F7PW@1|root,34048@2|Bacteria,1ZTZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1572857_6	379066.GAU_3014	2.63e-46	177.0	COG1595@1|root,COG1595@2|Bacteria,1ZTJF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_1572857_2	479434.Sthe_0784	7.314e-138	449.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi,27Y4R@189775|Thermomicrobia	189775|Thermomicrobia	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS3_k127_1572857_0	861299.J421_4260	1.768e-143	498.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HSJS3_k127_1572857_3	1442599.JAAN01000033_gene1697	3.433e-117	391.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1X34E@135614|Xanthomonadales	135614|Xanthomonadales	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HSJS3_k127_1572857_8	379066.GAU_0558	3.643e-13	71.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
HSJS3_k127_1573394_1	1265505.ATUG01000001_gene3682	1.504e-28	118.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HSJS3_k127_1573394_0	861299.J421_4163	2.683e-65	237.0	COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HSJS3_k127_1573394_2	861299.J421_4162	7.941e-26	115.0	COG0795@1|root,COG0795@2|Bacteria,1ZTJR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HSJS3_k127_1591823_3	1382356.JQMP01000004_gene234	5.276e-20	100.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi,27YGF@189775|Thermomicrobia	189775|Thermomicrobia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HSJS3_k127_1591823_0	1379698.RBG1_1C00001G0787	3.102e-149	501.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2NQNA@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid oxidation complex	fadJ	GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c26730,iETEC_1333.ETEC_2476,iEcE24377_1341.EcE24377A_2637,ic_1306.c2886	3HCDH,3HCDH_N,ECH_1
HSJS3_k127_1591823_2	1121413.JMKT01000010_gene824	4.116e-39	158.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HSJS3_k127_1591823_1	1125863.JAFN01000001_gene298	4.332e-86	296.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HSJS3_k127_1613001_4	379066.GAU_2313	6.13e-42	166.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1613001_2	1379270.AUXF01000004_gene3192	1.707e-199	631.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
HSJS3_k127_1613001_1	379066.GAU_2315	7.051e-278	878.0	COG0551@1|root,COG0551@2|Bacteria,1ZUEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
HSJS3_k127_1613001_3	1382306.JNIM01000001_gene1022	9.327e-56	205.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HSJS3_k127_1613001_0	391625.PPSIR1_18075	1.055e-285	892.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HSJS3_k127_1749813_4	867903.ThesuDRAFT_01182	9.022e-11	66.0	COG0843@1|root,COG0843@2|Bacteria,1TRC2@1239|Firmicutes	1239|Firmicutes	C	COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HSJS3_k127_1749813_1	1437824.BN940_02346	2.788e-54	196.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2VNRT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome c oxidase (Subunit II)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
HSJS3_k127_1749813_5	1071085.KK033114_gene895	0.0001546	46.0	arCOG11979@1|root,arCOG11979@2157|Archaea,2Y1FF@28890|Euryarchaeota,23YRK@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1749813_3	1382356.JQMP01000001_gene797	3.617e-27	116.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
HSJS3_k127_1749813_0	1123360.thalar_02888	1.248e-77	280.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2UQID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,FlpD
HSJS3_k127_1749813_6	1454004.AW11_01051	0.0004635	51.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1749813_2	1123368.AUIS01000035_gene81	4.451e-34	137.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
HSJS3_k127_1749836_3	177439.DP0686	4.308e-71	256.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,43BUE@68525|delta/epsilon subdivisions,2X75I@28221|Deltaproteobacteria,2MPKE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
HSJS3_k127_1749836_0	1343739.PAP_07985	1.699e-119	396.0	COG1883@1|root,arCOG04475@2157|Archaea,2XV43@28890|Euryarchaeota,24316@183968|Thermococci	183968|Thermococci	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
HSJS3_k127_1749836_8	1429046.RR21198_1894	1.025e-14	85.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4G0EH@85025|Nocardiaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HSJS3_k127_1749836_7	392499.Swit_3731	1.357e-20	96.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria,2K7CP@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HSJS3_k127_1749836_1	404589.Anae109_3873	7.805e-112	366.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,42YTV@68525|delta/epsilon subdivisions,2WTY1@28221|Deltaproteobacteria,2YYJ0@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
HSJS3_k127_1749836_5	1056820.KB900663_gene3810	1.25e-53	192.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,2PNX1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
HSJS3_k127_1749836_6	479434.Sthe_2046	1.282e-20	93.0	29U2R@1|root,30FC1@2|Bacteria,2G9M3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1749836_4	479434.Sthe_2045	2.314e-62	241.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	imuB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS
HSJS3_k127_1749836_2	631362.Thi970DRAFT_02146	8.23e-106	359.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1WW8I@135613|Chromatiales	135613|Chromatiales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HSJS3_k127_1823522_30	717605.Theco_2058	2.647e-09	64.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,26Y6Y@186822|Paenibacillaceae	91061|Bacilli	J	ribosomal protein	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
HSJS3_k127_1823522_3	1379270.AUXF01000005_gene820	5.989e-165	532.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
HSJS3_k127_1823522_29	379066.GAU_1553	1.019e-27	119.0	COG0779@1|root,COG0779@2|Bacteria,1ZTX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HSJS3_k127_1823522_2	861299.J421_3183	1.096e-168	540.0	COG0766@1|root,COG0766@2|Bacteria,1ZSZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HSJS3_k127_1823522_17	861299.J421_3181	2.864e-76	268.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
HSJS3_k127_1823522_4	644282.Deba_0849	1.847e-152	499.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HSJS3_k127_1823522_8	1382359.JIAL01000001_gene872	2.062e-147	484.0	COG0154@1|root,COG0154@2|Bacteria,3Y2PE@57723|Acidobacteria,2JIE0@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HSJS3_k127_1823522_31	1280953.HOC_09374	2.361e-06	58.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2UBSZ@28211|Alphaproteobacteria,43Y62@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HSJS3_k127_1823522_0	861299.J421_3177	1.139e-224	721.0	COG0210@1|root,COG0210@2|Bacteria,1ZTD5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HSJS3_k127_1823522_15	379066.GAU_1544	6.775e-79	278.0	COG5000@1|root,COG5000@2|Bacteria,1ZSKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HSJS3_k127_1823522_7	861299.J421_3175	6.542e-150	496.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HSJS3_k127_1823522_27	1219084.AP014508_gene1338	1.958e-31	130.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
HSJS3_k127_1823522_16	861299.J421_3170	6.298e-78	276.0	COG1208@1|root,COG1208@2|Bacteria,1ZSVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
HSJS3_k127_1823522_21	861299.J421_3169	7.714e-58	216.0	COG1235@1|root,COG1235@2|Bacteria,1ZTN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HSJS3_k127_1823522_18	868864.Dester_1526	2.114e-67	248.0	COG0750@1|root,COG0750@2|Bacteria,2G3QY@200783|Aquificae	200783|Aquificae	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HSJS3_k127_1823522_11	379066.GAU_1770	3.048e-113	382.0	COG0743@1|root,COG0743@2|Bacteria,1ZTFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
HSJS3_k127_1823522_25	861299.J421_3407	2.542e-37	153.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HSJS3_k127_1823522_22	880073.Calab_2293	9.413e-54	195.0	COG0233@1|root,COG0233@2|Bacteria,2NPEP@2323|unclassified Bacteria	2|Bacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HSJS3_k127_1823522_12	861299.J421_3410	7.532e-96	319.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HSJS3_k127_1823522_20	944479.JQLX01000015_gene80	3.672e-66	233.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2M6IY@213113|Desulfurellales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HSJS3_k127_1823522_13	1379270.AUXF01000006_gene119	6.756e-94	320.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HSJS3_k127_1823522_24	1120966.AUBU01000002_gene2027	2.671e-39	152.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,47Q9B@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HSJS3_k127_1823522_23	28258.KP05_04345	1.873e-53	192.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XJIQ@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HSJS3_k127_1823522_10	861299.J421_2922	8.478e-127	419.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS3_k127_1823522_19	861299.J421_2921	1.183e-66	238.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HSJS3_k127_1823522_1	379066.GAU_1166	3.93e-183	582.0	COG2204@1|root,COG2204@2|Bacteria,1ZT50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HSJS3_k127_1823522_26	335543.Sfum_2529	6.331e-33	136.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2MRXS@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
HSJS3_k127_1823522_6	479434.Sthe_2726	1.374e-151	499.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HSJS3_k127_1823522_9	1173029.JH980292_gene563	1.449e-127	421.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
HSJS3_k127_1823522_28	313612.L8106_29230	2.707e-30	123.0	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria,1HBSJ@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
HSJS3_k127_1823522_5	1173026.Glo7428_3013	8.514e-152	493.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
HSJS3_k127_1823522_14	945713.IALB_2412	2.283e-90	304.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	ddc	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
HSJS3_k127_1911838_1	330214.NIDE0760	1.06e-72	261.0	COG0772@1|root,COG0772@2|Bacteria,3J0M8@40117|Nitrospirae	40117|Nitrospirae	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HSJS3_k127_1911838_0	861299.J421_3074	1.289e-101	347.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HSJS3_k127_1911838_2	880073.Calab_2363	1.039e-47	173.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
HSJS3_k127_193697_1	1267211.KI669560_gene335	3.968e-195	628.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IX6D@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease C1 domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HSJS3_k127_193697_12	1123368.AUIS01000003_gene1811	1.934e-66	235.0	COG3931@1|root,COG3931@2|Bacteria,1QEPD@1224|Proteobacteria,1S4RU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
HSJS3_k127_193697_6	502025.Hoch_5783	3.249e-130	437.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glutamate-cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
HSJS3_k127_193697_2	502025.Hoch_5784	5.022e-173	557.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
HSJS3_k127_193697_11	502025.Hoch_5785	7.14e-76	262.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
HSJS3_k127_193697_10	869210.Marky_0140	3.894e-76	260.0	COG0566@1|root,COG0566@2|Bacteria,1WID3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
HSJS3_k127_193697_16	518766.Rmar_1602	2.509e-50	192.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,HTH_3
HSJS3_k127_193697_14	518766.Rmar_1601	2.973e-63	233.0	COG1562@1|root,COG2324@1|root,COG1562@2|Bacteria,COG2324@2|Bacteria,4PERW@976|Bacteroidetes,1FJHM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
HSJS3_k127_193697_21	1231241.Mc24_03488	6.937e-17	96.0	COG0142@1|root,COG0142@2|Bacteria	2|Bacteria	H	isoprenoid biosynthetic process	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HSJS3_k127_193697_15	861299.J421_1840	2.377e-53	215.0	COG1562@1|root,COG1562@2|Bacteria,1ZU4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
HSJS3_k127_193697_0	518766.Rmar_1598	2.04e-214	692.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1FIXT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HSJS3_k127_193697_7	378806.STAUR_2315	2.093e-129	430.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2YUBK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
HSJS3_k127_193697_8	391615.ABSJ01000055_gene1360	2.471e-103	375.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_7,Response_reg
HSJS3_k127_193697_20	927677.ALVU02000001_gene3793	2.219e-20	108.0	COG2199@1|root,COG2203@1|root,COG5278@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5278@2|Bacteria,1FZWU@1117|Cyanobacteria,1H61N@1142|Synechocystis	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_9
HSJS3_k127_193697_19	118005.AWNK01000013_gene904	1.473e-28	123.0	COG0745@1|root,COG0745@2|Bacteria	118005.AWNK01000013_gene904|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_193697_22	292415.Tbd_1268	7.195e-06	53.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG3850@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3850@2|Bacteria,1NWAF@1224|Proteobacteria,2WGYE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
HSJS3_k127_193697_9	215803.DB30_5887	1.484e-84	286.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HSJS3_k127_193697_13	1242864.D187_002005	2.156e-65	230.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,42ZK4@68525|delta/epsilon subdivisions,2WUTV@28221|Deltaproteobacteria,2YVBM@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
HSJS3_k127_193697_4	1379270.AUXF01000007_gene1043	4.946e-140	453.0	COG2876@1|root,COG2876@2|Bacteria,1ZSPH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
HSJS3_k127_193697_5	383372.Rcas_3075	4.411e-138	454.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi,375AG@32061|Chloroflexia	32061|Chloroflexia	E	PFAM fumarate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HSJS3_k127_193697_3	1128421.JAGA01000003_gene3441	1.005e-156	505.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
HSJS3_k127_193697_18	861299.J421_1325	2.696e-32	135.0	COG1438@1|root,COG1438@2|Bacteria,1ZU02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
HSJS3_k127_193697_17	861299.J421_3625	5.352e-40	151.0	COG3118@1|root,COG3118@2|Bacteria,1ZV4B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
HSJS3_k127_1947018_4	861299.J421_1716	4.447e-31	130.0	COG0526@1|root,COG0526@2|Bacteria,1ZTV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS3_k127_1947018_1	861299.J421_1717	4.56e-70	246.0	COG4232@1|root,COG4232@2|Bacteria,1ZSQP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Cytochrome C biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbD
HSJS3_k127_1947018_3	237368.SCABRO_02414	4.869e-35	144.0	COG2928@1|root,COG2928@2|Bacteria,2IZGR@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
HSJS3_k127_1947018_6	269799.Gmet_0815	3.274e-12	79.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
HSJS3_k127_1947018_2	1423144.Gal_02843	1.01e-37	154.0	29681@1|root,2ZTI1@2|Bacteria,1RA8W@1224|Proteobacteria,2U6CU@28211|Alphaproteobacteria,34E2V@302485|Phaeobacter	28211|Alphaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
HSJS3_k127_1947018_0	472759.Nhal_2971	3.967e-82	282.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS3_k127_1947018_5	649638.Trad_2233	7.85e-29	120.0	COG0614@1|root,COG0614@2|Bacteria,1WK02@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HSJS3_k127_1972734_0	861299.J421_0410	2.147e-66	239.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_1972734_1	1379270.AUXF01000004_gene2895	1.224e-48	184.0	COG1629@1|root,COG4771@2|Bacteria,1ZUM3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HSJS3_k127_2087117_10	861299.J421_1017	1.165e-49	189.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_1017|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2087117_12	861299.J421_1668	7.615e-34	134.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_2087117_7	1120983.KB894571_gene2277	1.399e-102	353.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,1JP1J@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
HSJS3_k127_2087117_5	1123229.AUBC01000006_gene1063	1.017e-121	419.0	COG1804@1|root,COG1804@2|Bacteria,1MU4A@1224|Proteobacteria,2TRSB@28211|Alphaproteobacteria,3JR7A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
HSJS3_k127_2087117_2	383372.Rcas_0019	5.313e-135	442.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,376ZQ@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
HSJS3_k127_2087117_4	1470593.BW43_05294	6.246e-122	402.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	mdeA	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HSJS3_k127_2087117_0	518766.Rmar_1486	1.37e-147	495.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FINA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HSJS3_k127_2087117_16	614083.AWQR01000025_gene3722	2.763e-21	97.0	COG2388@1|root,COG2388@2|Bacteria,1N6YS@1224|Proteobacteria,2VXW3@28216|Betaproteobacteria,4AI2Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
HSJS3_k127_2087117_1	861299.J421_3301	1.022e-136	443.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
HSJS3_k127_2087117_6	379066.GAU_1671	3.397e-117	388.0	COG2896@1|root,COG2896@2|Bacteria,1ZSMN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
HSJS3_k127_2087117_11	1382306.JNIM01000001_gene1158	8.165e-36	140.0	COG0314@1|root,COG0314@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
HSJS3_k127_2087117_17	861299.J421_3304	5.866e-12	69.0	COG1977@1|root,COG1977@2|Bacteria,1ZU69@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HSJS3_k127_2087117_14	765869.BDW_02565	3.175e-30	126.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2MUR4@213481|Bdellovibrionales,2WQA9@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_2087117_15	379066.GAU_1674	1.679e-29	124.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HSJS3_k127_2087117_3	379066.GAU_1675	1.233e-122	406.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HSJS3_k127_2087117_9	861299.J421_2372	7.315e-51	189.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
HSJS3_k127_2087117_8	266117.Rxyl_2547	2.015e-62	224.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4CQ38@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HSJS3_k127_2087117_13	861299.J421_3595	7.636e-33	130.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HSJS3_k127_2121265_9	935840.JAEQ01000021_gene4408	2.808e-11	64.0	2E3HM@1|root,32YG7@2|Bacteria,1NM0U@1224|Proteobacteria,2TZYE@28211|Alphaproteobacteria,43RX1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2121265_8	264201.pc0548	5.728e-17	85.0	COG1186@1|root,COG1186@2|Bacteria,2JH72@204428|Chlamydiae	204428|Chlamydiae	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
HSJS3_k127_2121265_3	1192034.CAP_1749	5.997e-74	263.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,2YVSY@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HSJS3_k127_2121265_6	861299.J421_0105	2.015e-31	136.0	28NRS@1|root,2ZBQZ@2|Bacteria,1ZV13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2121265_2	472759.Nhal_2694	3.975e-75	269.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1WWM3@135613|Chromatiales	135613|Chromatiales	S	PFAM Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
HSJS3_k127_2121265_5	861299.J421_2044	1.337e-53	215.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2121265_7	1385517.N800_07985	1.007e-26	117.0	COG1309@1|root,COG1309@2|Bacteria,1RHEM@1224|Proteobacteria,1S6XW@1236|Gammaproteobacteria,1X77E@135614|Xanthomonadales	135614|Xanthomonadales	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
HSJS3_k127_2121265_1	1121930.AQXG01000001_gene1200	4.786e-80	285.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HSJS3_k127_2121265_4	518766.Rmar_0880	6.291e-55	208.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1FJ10@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
HSJS3_k127_2121265_0	1121104.AQXH01000001_gene2028	1.91e-254	811.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HSJS3_k127_2176471_1	644966.Tmar_0122	4.299e-54	195.0	COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia	186801|Clostridia	S	ATP cob(I)alamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HSJS3_k127_2176471_4	1379270.AUXF01000001_gene2507	3.298e-07	60.0	2FCBU@1|root,344FF@2|Bacteria,1ZU39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2176471_3	1089550.ATTH01000001_gene1932	4.369e-43	172.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HSJS3_k127_2176471_0	525904.Tter_0543	1.719e-84	304.0	COG3294@1|root,COG3294@2|Bacteria,2NR9E@2323|unclassified Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
HSJS3_k127_2176471_2	861299.J421_2831	1.737e-49	190.0	COG0785@1|root,COG0785@2|Bacteria,1ZTJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
HSJS3_k127_2200310_73	1121124.JNIX01000013_gene1550	0.0003158	49.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2200310_48	1463936.JOJI01000059_gene6084	1.452e-47	181.0	COG0346@1|root,COG0346@2|Bacteria,2GRGB@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
HSJS3_k127_2200310_40	1379270.AUXF01000004_gene3199	1.848e-62	225.0	COG3342@1|root,COG3342@2|Bacteria,1ZUFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
HSJS3_k127_2200310_49	483219.LILAB_35130	4.299e-47	173.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HSJS3_k127_2200310_11	926560.KE387023_gene1159	1.709e-171	551.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HSJS3_k127_2200310_26	1121033.AUCF01000007_gene5866	2.038e-102	342.0	COG0115@1|root,COG0115@2|Bacteria,1MX5D@1224|Proteobacteria,2TRVR@28211|Alphaproteobacteria,2JQHN@204441|Rhodospirillales	204441|Rhodospirillales	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HSJS3_k127_2200310_72	670292.JH26_21880	0.0002874	51.0	COG1388@1|root,COG1388@2|Bacteria,1N46M@1224|Proteobacteria	1224|Proteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HSJS3_k127_2200310_53	1217720.ALOX01000032_gene199	1.766e-42	178.0	COG1402@1|root,COG1402@2|Bacteria,1R4JB@1224|Proteobacteria,2UA21@28211|Alphaproteobacteria,2JWRJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_2200310_22	379066.GAU_0121	9.082e-123	419.0	COG1402@1|root,COG1402@2|Bacteria,1ZUR7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
HSJS3_k127_2200310_8	1121930.AQXG01000010_gene3057	5.89e-191	627.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_2200310_42	671143.DAMO_2352	3.188e-60	223.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yeeZ	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
HSJS3_k127_2200310_69	1386089.N865_01860	3.832e-10	70.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4FE4F@85021|Intrasporangiaceae	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HSJS3_k127_2200310_31	448385.sce3874	2.246e-90	315.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42QVM@68525|delta/epsilon subdivisions,2WN3E@28221|Deltaproteobacteria,2YTVS@29|Myxococcales	28221|Deltaproteobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HSJS3_k127_2200310_9	525897.Dbac_1384	1.248e-185	591.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_2200310_68	479434.Sthe_0403	5.939e-11	74.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS3_k127_2200310_16	525904.Tter_2684	3.651e-156	510.0	COG2141@1|root,COG2141@2|Bacteria,2NQKB@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS3_k127_2200310_36	1173264.KI913949_gene2156	1.299e-70	253.0	COG0845@1|root,COG0845@2|Bacteria,1G29R@1117|Cyanobacteria,1H9Z0@1150|Oscillatoriales	1117|Cyanobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HSJS3_k127_2200310_3	349124.Hhal_1917	6.58e-212	684.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria,1WXMT@135613|Chromatiales	135613|Chromatiales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_2200310_30	748247.AZKH_1669	1.961e-90	317.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_2200310_67	379066.GAU_2309	1.294e-12	74.0	COG2010@1|root,COG2010@2|Bacteria,1ZT07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,HupE_UreJ_2
HSJS3_k127_2200310_24	234267.Acid_5043	7.17e-118	400.0	COG0026@1|root,COG0026@2|Bacteria,3Y3RI@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
HSJS3_k127_2200310_45	42256.RradSPS_2923	4.281e-55	200.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CQ7C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HSJS3_k127_2200310_7	313606.M23134_04351	3.818e-196	644.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,47KEQ@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM Aspartate kinase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
HSJS3_k127_2200310_55	134676.ACPL_2167	5.651e-40	167.0	COG4191@1|root,COG4191@2|Bacteria,2IF7B@201174|Actinobacteria	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
HSJS3_k127_2200310_62	1121448.DGI_2663	4.703e-21	98.0	COG0784@1|root,COG0784@2|Bacteria,1QUK7@1224|Proteobacteria,431U0@68525|delta/epsilon subdivisions,2WW6W@28221|Deltaproteobacteria,2MH8A@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HSJS3_k127_2200310_32	518766.Rmar_2408	2.12e-87	312.0	COG0745@1|root,COG2204@1|root,COG3852@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,4PN2Z@976|Bacteroidetes	976|Bacteroidetes	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
HSJS3_k127_2200310_71	1454004.AW11_01696	8.272e-08	60.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HSJS3_k127_2200310_47	861299.J421_2212	2.894e-50	193.0	COG0742@1|root,COG0742@2|Bacteria,1ZTNJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HSJS3_k127_2200310_54	1313421.JHBV01000007_gene4195	3.058e-41	171.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1IQ41@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HSJS3_k127_2200310_41	1121124.JNIX01000016_gene2092	1.059e-60	222.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,2KHP5@204458|Caulobacterales	204458|Caulobacterales	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
HSJS3_k127_2200310_14	665959.HMPREF1013_04029	1.133e-166	541.0	COG1960@1|root,COG1960@2|Bacteria,1TSVJ@1239|Firmicutes,4H9RM@91061|Bacilli,1ZCN6@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_2200310_35	1205680.CAKO01000002_gene2854	5.214e-71	260.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2TV0U@28211|Alphaproteobacteria,2JRPC@204441|Rhodospirillales	204441|Rhodospirillales	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N
HSJS3_k127_2200310_4	234267.Acid_3064	1.089e-208	711.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-oxidase_3,HYR,PAP2,PATR,P_proprotein,Peptidase_M14,Peptidase_M64,Peptidase_S8,SLH
HSJS3_k127_2200310_66	1005048.CFU_3476	5.618e-14	78.0	COG3794@1|root,COG3794@2|Bacteria,1RH5A@1224|Proteobacteria,2VSEN@28216|Betaproteobacteria,474NF@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
HSJS3_k127_2200310_0	379066.GAU_2315	1.312e-285	899.0	COG0551@1|root,COG0551@2|Bacteria,1ZUEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
HSJS3_k127_2200310_5	1379270.AUXF01000004_gene3192	5.447e-207	653.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
HSJS3_k127_2200310_12	1379270.AUXF01000003_gene3619	3.661e-168	551.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2200310_34	379066.GAU_3045	6.048e-80	280.0	COG0491@1|root,COG0491@2|Bacteria,1ZU73@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_2200310_25	1192034.CAP_4902	9.005e-108	362.0	COG1448@1|root,COG1448@2|Bacteria	2|Bacteria	E	Aminotransferase	tyrB	GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0008793,GO:0009058,GO:0009066,GO:0009067,GO:0009072,GO:0009073,GO:0009081,GO:0009082,GO:0009094,GO:0009095,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019292,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050048,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECED1_1282.ECED1_4768,iECSE_1348.ECSE_4347,iJN746.PP_3590,iLF82_1304.LF82_2339,iNRG857_1313.NRG857_20250,iPC815.YPO1410,iSFxv_1172.SFxv_1000,iUTI89_1310.UTI89_C4629	Aminotran_1_2
HSJS3_k127_2200310_61	379066.GAU_2316	6.038e-23	109.0	COG3836@1|root,COG3836@2|Bacteria,1ZU9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HSJS3_k127_2200310_46	1089550.ATTH01000001_gene765	6.022e-51	188.0	2CDT7@1|root,2ZZ6E@2|Bacteria,4PERQ@976|Bacteroidetes,1FJHB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2200310_33	1532558.JL39_15995	1.35e-84	297.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,4B8GN@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767,ko:K03813	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HSJS3_k127_2200310_19	1120983.KB894572_gene2860	1.925e-138	449.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,1JNHB@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	Quinolinate synthetase A protein	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HSJS3_k127_2200310_43	1396858.Q666_00060	2.654e-58	211.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,466UT@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	mip	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
HSJS3_k127_2200310_70	861299.J421_3542	4.968e-08	62.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
HSJS3_k127_2200310_60	309807.SRU_1340	9.674e-25	106.0	COG1534@1|root,COG1534@2|Bacteria,4PF83@976|Bacteroidetes,1FK9S@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
HSJS3_k127_2200310_65	1049564.TevJSym_aa00710	5.203e-14	79.0	2EANF@1|root,334QY@2|Bacteria,1N8X0@1224|Proteobacteria,1SCTI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2200310_13	1121104.AQXH01000001_gene1688	1.771e-167	551.0	COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1IQZ9@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2200310_17	504472.Slin_2735	7.562e-139	456.0	COG2041@1|root,COG2041@2|Bacteria,4NEIQ@976|Bacteroidetes,47MW5@768503|Cytophagia	976|Bacteroidetes	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
HSJS3_k127_2200310_52	471854.Dfer_1616	1.517e-42	181.0	COG2010@1|root,COG2010@2|Bacteria,4NM76@976|Bacteroidetes,47PI1@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
HSJS3_k127_2200310_38	1033802.SSPSH_000463	1.745e-64	234.0	COG3108@1|root,COG3108@2|Bacteria,1RAMQ@1224|Proteobacteria,1S35S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
HSJS3_k127_2200310_21	439235.Dalk_3479	3.865e-131	443.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2WKBM@28221|Deltaproteobacteria,2MHN3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
HSJS3_k127_2200310_29	518766.Rmar_0141	1.037e-90	312.0	COG0668@1|root,COG0668@2|Bacteria,4NMNE@976|Bacteroidetes	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
HSJS3_k127_2200310_39	518766.Rmar_0142	1.45e-63	249.0	COG1672@1|root,COG1672@2|Bacteria,4NN64@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2200310_56	1268622.AVS7_00792	9.282e-38	154.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKYM@28216|Betaproteobacteria,4AA9N@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HSJS3_k127_2200310_1	278963.ATWD01000001_gene2416	5.932e-247	773.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
HSJS3_k127_2200310_50	1089550.ATTH01000002_gene10	2.612e-46	171.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1FK4G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HSJS3_k127_2200310_37	518766.Rmar_0269	2.05e-67	237.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1FK1T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HSJS3_k127_2200310_59	33898.JRHJ01000069_gene7445	3.01e-25	120.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria	201174|Actinobacteria	Q	beta-lactamase domain protein	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
HSJS3_k127_2200310_2	234267.Acid_3515	8.031e-240	767.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_2200310_15	1161401.ASJA01000004_gene2178	6.167e-166	537.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2TRSE@28211|Alphaproteobacteria,43WF5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HSJS3_k127_2200310_51	861299.J421_2069	8.057e-46	173.0	COG0234@1|root,COG0234@2|Bacteria,1ZU6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
HSJS3_k127_2200310_27	867903.ThesuDRAFT_00992	1.333e-92	324.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
HSJS3_k127_2200310_63	1379270.AUXF01000002_gene1759	1.466e-18	96.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	mutT	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55,3.6.1.65	ko:K03574,ko:K08320	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129	NUDIX,NUDIX_4,TMP-TENI
HSJS3_k127_2200310_23	518766.Rmar_1990	3.921e-121	406.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
HSJS3_k127_2200310_44	1379270.AUXF01000002_gene1485	9.735e-58	213.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	blaB3	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_2200310_6	1121920.AUAU01000005_gene1052	7.5e-204	651.0	COG3604@1|root,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
HSJS3_k127_2200310_57	1158318.ATXC01000001_gene1003	6.946e-37	141.0	COG0347@1|root,COG0347@2|Bacteria,2G43N@200783|Aquificae	200783|Aquificae	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HSJS3_k127_2200310_10	439235.Dalk_3033	1.219e-179	574.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HSJS3_k127_2200310_18	243231.GSU1820	1.898e-138	473.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
HSJS3_k127_2200310_20	1121405.dsmv_1337	6.789e-134	434.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2WIVJ@28221|Deltaproteobacteria,2MIV0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
HSJS3_k127_221775_2	234267.Acid_1255	2.511e-99	334.0	COG0451@1|root,COG0451@2|Bacteria,3Y5IZ@57723|Acidobacteria	57723|Acidobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HSJS3_k127_221775_1	935863.AWZR01000005_gene2169	1.566e-101	346.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1XC3M@135614|Xanthomonadales	135614|Xanthomonadales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS3_k127_221775_3	1449126.JQKL01000009_gene342	1.299e-27	117.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,268ZE@186813|unclassified Clostridiales	186801|Clostridia	K	Psort location Cytoplasmic, score	cadC	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HSJS3_k127_221775_0	795797.C497_04262	5.267e-123	417.0	COG2217@1|root,arCOG02764@1|root,arCOG01576@2157|Archaea,arCOG02764@2157|Archaea,2XTD8@28890|Euryarchaeota,23SNP@183963|Halobacteria	183963|Halobacteria	P	COG2217 Cation transport ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HSJS3_k127_2273214_4	485913.Krac_3074	4.518e-82	280.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
HSJS3_k127_2273214_3	518766.Rmar_1253	1.46e-110	372.0	COG2715@1|root,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1FISA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleoside recognition	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HSJS3_k127_2273214_5	1089550.ATTH01000001_gene816	7.402e-78	265.0	COG0700@1|root,COG0700@2|Bacteria,4PM62@976|Bacteroidetes,1FJ72@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleoside recognition	-	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
HSJS3_k127_2273214_2	204669.Acid345_2620	6.831e-128	426.0	COG0773@1|root,COG0773@2|Bacteria,3Y2M2@57723|Acidobacteria,2JIE2@204432|Acidobacteriia	204432|Acidobacteriia	M	Mur ligase middle domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_2273214_1	448385.sce8554	4.317e-138	461.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YU0V@29|Myxococcales	28221|Deltaproteobacteria	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HSJS3_k127_2273214_7	379066.GAU_2718	4.941e-63	231.0	COG1619@1|root,COG1619@2|Bacteria,1ZTIC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HSJS3_k127_2273214_8	935261.JAGL01000026_gene689	3.107e-55	197.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,43KJG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	YCII-related domain	MA20_04055	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS3_k127_2273214_6	215803.DB30_7311	7.484e-73	263.0	COG2010@1|root,COG2010@2|Bacteria,1QX4J@1224|Proteobacteria,437VA@68525|delta/epsilon subdivisions,2X34V@28221|Deltaproteobacteria,2YUNT@29|Myxococcales	28221|Deltaproteobacteria	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,Cu2_monooxygen
HSJS3_k127_2273214_0	309807.SRU_2257	1.145e-281	885.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1FJSS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
HSJS3_k127_2529451_0	338969.Rfer_0414	1.255e-36	141.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,2VQH7@28216|Betaproteobacteria,4AGU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HSJS3_k127_2529451_1	694427.Palpr_2946	1.163e-19	94.0	2BFHQ@1|root,329BH@2|Bacteria,4P73M@976|Bacteroidetes,2FZWT@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2529451_2	1406840.Q763_16590	8.511e-06	56.0	28JZK@1|root,2Z9PJ@2|Bacteria,4NIWX@976|Bacteroidetes,1I16C@117743|Flavobacteriia,2NXXN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_260129_31	1121930.AQXG01000001_gene1352	0.0006363	46.0	2EAWV@1|root,334Y2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_260129_19	926562.Oweho_2422	6.042e-43	167.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
HSJS3_k127_260129_29	1379270.AUXF01000005_gene835	2.242e-13	80.0	2F5A9@1|root,33XWF@2|Bacteria,1ZTU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_260129_25	861299.J421_3201	3.073e-22	106.0	2EPTK@1|root,33HE4@2|Bacteria,1ZTUK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
HSJS3_k127_260129_15	1238182.C882_4238	1.239e-48	179.0	COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,2UBYN@28211|Alphaproteobacteria,2JTMZ@204441|Rhodospirillales	204441|Rhodospirillales	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
HSJS3_k127_260129_21	1033802.SSPSH_001588	2.258e-31	126.0	COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria,1SE40@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Multiple resistance and pH regulation protein F	mnhF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
HSJS3_k127_260129_26	1123355.JHYO01000024_gene1812	3.452e-18	92.0	COG1320@1|root,COG1320@2|Bacteria,1N75I@1224|Proteobacteria,2UETR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	monovalent cation proton antiporter, MnhG PhaG subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
HSJS3_k127_260129_12	402881.Plav_2970	1.104e-59	213.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,2U7UT@28211|Alphaproteobacteria,1JQ4B@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Domain of unknown function (DUF4040)	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040
HSJS3_k127_260129_20	1304275.C41B8_05753	1.883e-40	159.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na H antiporter, MnhB	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040,MnhB
HSJS3_k127_260129_18	2340.JV46_13160	3.241e-43	160.0	COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,1S6BB@1236|Gammaproteobacteria,1J68T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
HSJS3_k127_260129_4	425104.Ssed_3666	7.13e-168	547.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,2QAGX@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
HSJS3_k127_260129_2	1198232.CYCME_1781	1.147e-179	575.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,1T20X@1236|Gammaproteobacteria,463WT@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
HSJS3_k127_260129_27	1336233.JAEH01000001_gene756	1.057e-16	85.0	2EAIM@1|root,334MN@2|Bacteria,1N6XM@1224|Proteobacteria,1SF6C@1236|Gammaproteobacteria,2QCJS@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_260129_1	1122134.KB893651_gene2100	2.96e-231	728.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,1RQK5@1236|Gammaproteobacteria,1XI22@135619|Oceanospirillales	135619|Oceanospirillales	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
HSJS3_k127_260129_30	1232427.CAVS020000012_gene1340	7.474e-12	76.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,22KPZ@1653|Corynebacteriaceae	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
HSJS3_k127_260129_14	1121459.AQXE01000005_gene1524	1.398e-50	189.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria,2MBFN@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
HSJS3_k127_260129_9	1379270.AUXF01000005_gene838	1.036e-83	284.0	COG0689@1|root,COG0689@2|Bacteria,1ZSYT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
HSJS3_k127_260129_13	861299.J421_3204	1.177e-52	200.0	COG0127@1|root,COG0127@2|Bacteria,1ZTSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HSJS3_k127_260129_24	1379698.RBG1_1C00001G0517	8.569e-23	104.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HSJS3_k127_260129_7	234267.Acid_4084	8.338e-99	339.0	COG2421@1|root,COG2421@2|Bacteria,3Y40F@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
HSJS3_k127_260129_28	479431.Namu_4048	1.596e-15	89.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4EVE7@85013|Frankiales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HSJS3_k127_260129_3	246197.MXAN_5426	8.065e-170	554.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YZRQ@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
HSJS3_k127_260129_17	1267535.KB906767_gene904	6.907e-48	185.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
HSJS3_k127_260129_22	1210884.HG799465_gene11440	2.049e-27	119.0	28WG9@1|root,2ZIGE@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HSJS3_k127_260129_10	379066.GAU_3418	8.894e-75	262.0	COG1402@1|root,COG1402@2|Bacteria,1ZUCY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
HSJS3_k127_260129_8	1267535.KB906767_gene4866	4.542e-85	293.0	COG2863@1|root,COG2863@2|Bacteria	2|Bacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3,DUF1566
HSJS3_k127_260129_11	1142394.PSMK_13220	2.981e-66	229.0	COG2343@1|root,COG2343@2|Bacteria,2J097@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
HSJS3_k127_260129_16	1235457.C404_06955	2.805e-48	188.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VMPC@28216|Betaproteobacteria,1K5RV@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HSJS3_k127_260129_0	251229.Chro_5330	3.11e-259	813.0	COG1132@1|root,COG1132@2|Bacteria,1G0EY@1117|Cyanobacteria,3VISV@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS3_k127_260129_23	888833.HMPREF9421_1500	2.205e-24	106.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli	91061|Bacilli	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HSJS3_k127_260129_5	925409.KI911562_gene1602	6.359e-159	509.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1INWU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HSJS3_k127_260129_6	1283300.ATXB01000001_gene1150	1.203e-142	460.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1XE2G@135618|Methylococcales	135618|Methylococcales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
HSJS3_k127_2687488_22	379066.GAU_2186	1.303e-29	120.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HSJS3_k127_2687488_25	1265502.KB905933_gene1978	4.564e-19	90.0	COG2388@1|root,COG2388@2|Bacteria,1PN9N@1224|Proteobacteria,2VW1K@28216|Betaproteobacteria,4AFP4@80864|Comamonadaceae	28216|Betaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
HSJS3_k127_2687488_15	709032.Sulku_1100	2.399e-52	199.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
HSJS3_k127_2687488_24	316274.Haur_0275	1.979e-21	99.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS3_k127_2687488_11	1236541.BALL01000021_gene2736	5.385e-73	257.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,2Q8QS@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HSJS3_k127_2687488_13	861299.J421_1231	3.725e-69	265.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1231|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
HSJS3_k127_2687488_16	861299.J421_0625	4.204e-50	185.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
HSJS3_k127_2687488_4	43989.cce_0694	6.054e-117	386.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,3KJEA@43988|Cyanothece	1117|Cyanobacteria	M	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
HSJS3_k127_2687488_20	1392493.JIAB01000001_gene1199	1.999e-38	165.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,27I77@186928|unclassified Lachnospiraceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
HSJS3_k127_2687488_8	452637.Oter_1528	3.485e-78	269.0	COG4555@1|root,COG4555@2|Bacteria	2|Bacteria	CP	ABC transporter	natA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	iYO844.BSU02750	ABC_tran
HSJS3_k127_2687488_21	1142394.PSMK_20110	1.209e-34	149.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,2IXUG@203682|Planctomycetes	203682|Planctomycetes	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane_2,Abi
HSJS3_k127_2687488_27	1033734.CAET01000077_gene2899	2.024e-11	72.0	COG3369@1|root,COG3369@2|Bacteria,1VFK3@1239|Firmicutes,4HNHY@91061|Bacilli,1ZIZQ@1386|Bacillus	91061|Bacilli	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
HSJS3_k127_2687488_1	644966.Tmar_1012	9.042e-190	600.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WCC9@538999|Clostridiales incertae sedis	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
HSJS3_k127_2687488_19	1144275.COCOR_03636	2.329e-43	178.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
HSJS3_k127_2687488_5	1122194.AUHU01000008_gene3329	5.459e-98	337.0	COG0834@1|root,COG0834@2|Bacteria,1NN6F@1224|Proteobacteria,1RZ35@1236|Gammaproteobacteria,467ZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	ET	Ligand-gated ion channel	-	-	-	ko:K02030,ko:K10036	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.2	-	-	Lig_chan,SBP_bac_3
HSJS3_k127_2687488_0	388413.ALPR1_11530	8.436e-218	702.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,47MK3@768503|Cytophagia	976|Bacteroidetes	S	glutamate carboxypeptidase	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
HSJS3_k127_2687488_2	1340493.JNIF01000003_gene4071	3.185e-139	457.0	COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_2687488_23	1379270.AUXF01000001_gene2139	6.079e-22	100.0	COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_2687488_7	1379270.AUXF01000001_gene1961	6.748e-82	282.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_2687488_6	1379270.AUXF01000001_gene1962	5.751e-83	299.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_2687488_12	497321.C664_15313	9.136e-73	257.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2VIH3@28216|Betaproteobacteria,2KVPA@206389|Rhodocyclales	206389|Rhodocyclales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HSJS3_k127_2687488_18	765952.PUV_14650	1.918e-49	188.0	COG0494@1|root,COG0494@2|Bacteria,2JGDU@204428|Chlamydiae	204428|Chlamydiae	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HSJS3_k127_2687488_26	1079460.ATTQ01000005_gene2386	2.011e-14	81.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria,4BENB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Cupin 2 conserved barrel domain protein	MA20_13155	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS3_k127_2687488_10	861299.J421_0082	1.557e-75	271.0	28M10@1|root,2ZAFW@2|Bacteria,1ZSP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
HSJS3_k127_2687488_3	929556.Solca_0511	4.703e-130	450.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IRAR@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
HSJS3_k127_2687488_14	290397.Adeh_1509	5.616e-61	222.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the phosphatidylserine decarboxylase family	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HSJS3_k127_2687488_17	518766.Rmar_0644	1.337e-49	192.0	COG0845@1|root,COG0845@2|Bacteria,4NHJH@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HSJS3_k127_2687488_28	794903.OPIT5_18660	0.0002585	53.0	COG1538@1|root,COG1538@2|Bacteria,46T0P@74201|Verrucomicrobia,3K73I@414999|Opitutae	414999|Opitutae	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HSJS3_k127_2687488_9	945713.IALB_0693	4.281e-78	277.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	mdtC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HSJS3_k127_2705100_1	1496688.ER33_15955	1.882e-76	270.0	COG1364@1|root,COG1364@2|Bacteria,1G1H7@1117|Cyanobacteria,22S9R@167375|Cyanobium	1117|Cyanobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argJ	ArgJ
HSJS3_k127_2705100_2	1449126.JQKL01000028_gene2601	4.745e-39	166.0	COG1246@1|root,COG1246@2|Bacteria,1V6TZ@1239|Firmicutes,24KQF@186801|Clostridia	186801|Clostridia	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HSJS3_k127_2705100_0	644966.Tmar_0537	2.109e-95	326.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WCR1@538999|Clostridiales incertae sedis	186801|Clostridia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS3_k127_2713660_0	945713.IALB_0006	3.05e-246	785.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HSJS3_k127_2713660_1	861299.J421_2400	1.029e-119	396.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
HSJS3_k127_2713660_2	344747.PM8797T_25601	2.94e-55	203.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PDZ_2,Peptidase_M28
HSJS3_k127_2733493_0	1382306.JNIM01000001_gene264	2.466e-108	356.0	COG3396@1|root,COG3396@2|Bacteria,2G9AI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HSJS3_k127_2733493_1	1118054.CAGW01000061_gene2428	1.045e-29	123.0	COG2151@1|root,COG2151@2|Bacteria,1VE3S@1239|Firmicutes,4HKP6@91061|Bacilli	91061|Bacilli	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
HSJS3_k127_2733493_3	1118054.CAGW01000061_gene2429	1.21e-15	79.0	2DTNH@1|root,33M2H@2|Bacteria,1W1AW@1239|Firmicutes,4HZ7K@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2733493_2	1382306.JNIM01000001_gene267	5.263e-23	110.0	COG3396@1|root,COG3396@2|Bacteria,2G9KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HSJS3_k127_2795245_3	760568.Desku_1207	2.669e-107	353.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HSJS3_k127_2795245_6	861299.J421_3350	2.008e-99	337.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HSJS3_k127_2795245_4	861299.J421_1451	1.428e-106	366.0	COG0661@1|root,COG0661@2|Bacteria,1ZSYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
HSJS3_k127_2795245_5	1270196.JCKI01000004_gene882	2.904e-104	359.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HSJS3_k127_2795245_12	379066.GAU_1713	5.899e-25	110.0	COG0319@1|root,COG0319@2|Bacteria,1ZTUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
HSJS3_k127_2795245_1	861299.J421_3354	4.496e-134	464.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
HSJS3_k127_2795245_2	379066.GAU_1714	7.166e-113	383.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HSJS3_k127_2795245_0	861299.J421_3356	5.359e-204	655.0	COG0173@1|root,COG0173@2|Bacteria,1ZTFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HSJS3_k127_2795245_13	290397.Adeh_2354	4.565e-14	78.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HSJS3_k127_2795245_7	1379270.AUXF01000006_gene172	2.072e-95	324.0	COG0820@1|root,COG0820@2|Bacteria,1ZTAJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
HSJS3_k127_2795245_8	861299.J421_2921	3.928e-61	219.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HSJS3_k127_2795245_14	379066.GAU_1718	9.856e-10	69.0	2E48Y@1|root,32Z4R@2|Bacteria,1ZV5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
HSJS3_k127_2795245_11	379066.GAU_1719	4.886e-33	136.0	COG1713@1|root,COG1713@2|Bacteria,1ZTTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	HD superfamily hydrolase involved in NAD metabolism	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HSJS3_k127_2795245_10	751945.Theos_1355	2.286e-44	181.0	COG1293@1|root,COG1293@2|Bacteria,1WJ78@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
HSJS3_k127_2795245_9	639283.Snov_3924	1.791e-49	183.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2TQN2@28211|Alphaproteobacteria,3EY1C@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HSJS3_k127_2874503_9	314345.SPV1_09338	3.885e-29	117.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria	1224|Proteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HSJS3_k127_2874503_0	1048834.TC41_2255	1.659e-174	556.0	COG1830@1|root,COG1830@2|Bacteria,1TR60@1239|Firmicutes,4HT90@91061|Bacilli	91061|Bacilli	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
HSJS3_k127_2874503_5	1453496.AT03_03735	1.559e-87	304.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RZAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	aminotransferase	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_2874503_1	1356852.N008_09615	1.013e-113	386.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,47MY8@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HSJS3_k127_2874503_10	1340493.JNIF01000003_gene4229	6.284e-29	122.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
HSJS3_k127_2874503_11	118173.KB235914_gene3240	2.675e-26	115.0	COG3631@1|root,COG3631@2|Bacteria,1GDTN@1117|Cyanobacteria,1HH10@1150|Oscillatoriales	1117|Cyanobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2874503_3	945713.IALB_0139	3.741e-100	369.0	COG1301@1|root,COG1301@2|Bacteria	2|Bacteria	C	dicarboxylic acid transport	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
HSJS3_k127_2874503_2	861299.J421_0779	2.809e-100	369.0	COG0652@1|root,COG0652@2|Bacteria,1ZTYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HSJS3_k127_2874503_6	1117108.PAALTS15_01155	9.121e-68	240.0	COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,4HCP9@91061|Bacilli,275W8@186822|Paenibacillaceae	91061|Bacilli	K	PaaX-like protein	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
HSJS3_k127_2874503_4	697281.Mahau_2241	8.903e-88	306.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,42FUG@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47,6.2.1.14	ko:K00639,ko:K00652,ko:K01906	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03209,R03210,R10124	RC00004,RC00014,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_2874503_7	309807.SRU_2309	6.592e-53	194.0	COG1028@1|root,COG1028@2|Bacteria,4NGAH@976|Bacteroidetes	976|Bacteroidetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HSJS3_k127_2874503_8	309801.trd_A0259	1.366e-36	154.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
HSJS3_k127_2876224_4	1283299.AUKG01000001_gene2424	1.727e-45	171.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
HSJS3_k127_2876224_0	926569.ANT_00930	5.721e-196	628.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
HSJS3_k127_2876224_3	861299.J421_1026	2.13e-86	298.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
HSJS3_k127_2876224_2	1278073.MYSTI_01766	7.051e-94	340.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_2876224_5	234267.Acid_2305	8.943e-20	94.0	COG1695@1|root,COG1695@2|Bacteria,3Y5ZC@57723|Acidobacteria	57723|Acidobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_2876224_1	997346.HMPREF9374_2257	4.136e-115	381.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,27BPV@186824|Thermoactinomycetaceae	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HSJS3_k127_2883910_11	861299.J421_3065	6.254e-31	135.0	2DUTE@1|root,33S5W@2|Bacteria,1ZSMI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2883910_2	1379270.AUXF01000005_gene674	2.261e-102	353.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
HSJS3_k127_2883910_3	379066.GAU_1411	1.116e-94	334.0	COG0593@1|root,COG0593@2|Bacteria,1ZUFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bacterial dnaA  protein	-	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA
HSJS3_k127_2883910_4	1125863.JAFN01000001_gene3379	1.311e-85	297.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HSJS3_k127_2883910_0	861299.J421_3048	0.0	1103.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HSJS3_k127_2883910_14	913865.DOT_3794	1.111e-13	82.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,262G3@186807|Peptococcaceae	186801|Clostridia	D	PFAM DivIVA	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
HSJS3_k127_2883910_9	644966.Tmar_0879	4.562e-49	186.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WCI6@538999|Clostridiales incertae sedis	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HSJS3_k127_2883910_15	1158292.JPOE01000002_gene1436	2.275e-09	67.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HSJS3_k127_2883910_13	880073.Calab_2426	1.784e-14	79.0	COG0848@1|root,COG0848@2|Bacteria,2NRQH@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
HSJS3_k127_2883910_12	880073.Calab_2425	1.218e-17	88.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
HSJS3_k127_2883910_10	1089550.ATTH01000001_gene2396	3.16e-38	154.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1FIYM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HSJS3_k127_2883910_5	861299.J421_3044	9.416e-81	277.0	COG1624@1|root,COG1624@2|Bacteria,1ZUI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HSJS3_k127_2883910_1	1379270.AUXF01000005_gene656	2.309e-244	771.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
HSJS3_k127_2883910_8	379066.GAU_1392	8.582e-51	202.0	COG0634@1|root,COG0634@2|Bacteria,1ZTH7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HSJS3_k127_2883910_6	1122919.KB905597_gene4270	1.128e-53	208.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HSJS3_k127_2883910_7	266117.Rxyl_1999	4.822e-51	191.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4CQHH@84995|Rubrobacteria	84995|Rubrobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
HSJS3_k127_2893670_0	861299.J421_2266	9.293e-190	610.0	COG3653@1|root,COG3653@2|Bacteria,1ZTDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HSJS3_k127_2893670_3	1382304.JNIL01000001_gene97	8.988e-14	81.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,SoxE
HSJS3_k127_2893670_1	388051.AUFE01000012_gene2920	2.796e-82	284.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,1K1V9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Pfam Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HSJS3_k127_2893670_2	240015.ACP_2502	1.946e-27	122.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_2898024_0	1380394.JADL01000024_gene101	6.514e-239	750.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JRCI@204441|Rhodospirillales	204441|Rhodospirillales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
HSJS3_k127_2898024_2	1122604.JONR01000004_gene853	8.199e-39	167.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria,1XDC3@135614|Xanthomonadales	135614|Xanthomonadales	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2898024_1	1128421.JAGA01000001_gene2194	8.014e-68	241.0	COG2986@1|root,COG2986@2|Bacteria,2NNRU@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
HSJS3_k127_2903463_47	1304875.JAFZ01000004_gene476	1.122e-13	73.0	2DD8T@1|root,2ZH33@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2903463_21	861299.J421_4228	5.513e-95	330.0	28P8D@1|root,33Q3E@2|Bacteria,1ZU8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
HSJS3_k127_2903463_3	861299.J421_4227	1.124e-230	756.0	COG1629@1|root,COG4771@2|Bacteria,1ZUM3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HSJS3_k127_2903463_9	861299.J421_3434	2.189e-156	510.0	COG0497@1|root,COG0497@2|Bacteria,1ZSV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
HSJS3_k127_2903463_35	861299.J421_3435	3.944e-55	206.0	COG0061@1|root,COG0061@2|Bacteria,1ZT32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HSJS3_k127_2903463_4	861299.J421_3436	1.265e-225	717.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HSJS3_k127_2903463_26	379066.GAU_1867	5.617e-75	265.0	COG0142@1|root,COG0142@2|Bacteria,1ZSR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HSJS3_k127_2903463_51	1144275.COCOR_04850	4.46e-06	57.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MM@1224|Proteobacteria,42X37@68525|delta/epsilon subdivisions,2WSNI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HSJS3_k127_2903463_19	861299.J421_3439	2.767e-101	347.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HSJS3_k127_2903463_16	1121403.AUCV01000002_gene556	4.206e-111	366.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2MHRX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HSJS3_k127_2903463_7	861299.J421_3441	2.685e-172	555.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HSJS3_k127_2903463_49	861299.J421_3442	6.788e-11	66.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HSJS3_k127_2903463_8	1379270.AUXF01000006_gene86	8.182e-167	562.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1ZSWJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HSJS3_k127_2903463_17	861299.J421_3445	4.96e-110	367.0	COG0016@1|root,COG0016@2|Bacteria,1ZSQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HSJS3_k127_2903463_41	1379270.AUXF01000006_gene84	6.118e-41	154.0	COG0292@1|root,COG0292@2|Bacteria,1ZTUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HSJS3_k127_2903463_46	1443122.Z958_08715	1.196e-16	81.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,36MNG@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HSJS3_k127_2903463_32	379066.GAU_1878	1.077e-59	222.0	COG0290@1|root,COG0290@2|Bacteria,1ZTM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HSJS3_k127_2903463_2	379066.GAU_1285	2.619e-260	817.0	COG0441@1|root,COG0441@2|Bacteria,1ZT2I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HSJS3_k127_2903463_20	545276.KB898724_gene2028	3.968e-96	349.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1S0YE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	GTP cyclohydrolase II	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
HSJS3_k127_2903463_11	314278.NB231_03260	8.182e-153	519.0	COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,1RMGX@1236|Gammaproteobacteria,1WWAY@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K03669	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.3.1.1	GT2	-	Glyco_trans_2_3,Glycos_transf_2
HSJS3_k127_2903463_10	1255043.TVNIR_1289	8.966e-154	505.0	COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,1WVW5@135613|Chromatiales	135613|Chromatiales	P	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)	-	-	-	ko:K03670	-	-	-	-	ko00000	-	-	-	MdoG
HSJS3_k127_2903463_14	1255043.TVNIR_1287	2.065e-124	435.0	COG3119@1|root,COG3119@2|Bacteria,1PWEJ@1224|Proteobacteria,1RZ2R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HSJS3_k127_2903463_23	1255043.TVNIR_1800	7.155e-87	302.0	COG4076@1|root,COG4076@2|Bacteria,1QXIM@1224|Proteobacteria,1T3CA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HSJS3_k127_2903463_25	545276.KB898724_gene2051	1.569e-79	284.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1S16H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_2903463_27	1266914.ATUK01000001_gene809	2.698e-71	253.0	COG1985@1|root,COG1985@2|Bacteria,1RES9@1224|Proteobacteria,1S3BT@1236|Gammaproteobacteria,1WYR6@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HSJS3_k127_2903463_38	85643.Tmz1t_2457	2.532e-52	208.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,2VPUX@28216|Betaproteobacteria,2KZIN@206389|Rhodocyclales	206389|Rhodocyclales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
HSJS3_k127_2903463_31	713587.THITH_08015	6.524e-62	228.0	COG0438@1|root,COG0438@2|Bacteria,1QZ3G@1224|Proteobacteria,1T4PT@1236|Gammaproteobacteria,1X2UP@135613|Chromatiales	135613|Chromatiales	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2903463_22	1266908.AQPB01000048_gene2155	3.996e-91	317.0	COG0438@1|root,COG0438@2|Bacteria,1P81Z@1224|Proteobacteria,1RYFP@1236|Gammaproteobacteria,1WZ87@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_2903463_34	497321.C664_07118	2.251e-56	199.0	COG0720@1|root,COG0720@2|Bacteria,1RI8E@1224|Proteobacteria,2VTBS@28216|Betaproteobacteria	28216|Betaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PTPS
HSJS3_k127_2903463_15	331869.BAL199_21974	1.068e-114	379.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,2U09B@28211|Alphaproteobacteria,4BQQE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C
HSJS3_k127_2903463_40	1158762.KB898038_gene2037	2.319e-44	171.0	COG0558@1|root,COG0558@2|Bacteria,1N1AE@1224|Proteobacteria,1SBCI@1236|Gammaproteobacteria,1X1ZI@135613|Chromatiales	135613|Chromatiales	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
HSJS3_k127_2903463_24	861299.J421_2931	1.054e-85	304.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
HSJS3_k127_2903463_5	469371.Tbis_2156	2.106e-219	707.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4DYAF@85010|Pseudonocardiales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HSJS3_k127_2903463_0	234267.Acid_4922	4.98e-285	894.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HSJS3_k127_2903463_29	90814.KL370891_gene896	9.803e-66	235.0	COG3391@1|root,COG3391@2|Bacteria,1RGAJ@1224|Proteobacteria,1S2QK@1236|Gammaproteobacteria,462Y7@72273|Thiotrichales	72273|Thiotrichales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
HSJS3_k127_2903463_37	379066.GAU_3100	3.345e-53	203.0	29X7K@1|root,30IWU@2|Bacteria,1ZUTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
HSJS3_k127_2903463_6	861299.J421_6286	1.89e-191	616.0	COG3653@1|root,COG3653@2|Bacteria,1ZTFY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HSJS3_k127_2903463_1	861299.J421_3164	4.219e-271	842.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HSJS3_k127_2903463_43	1379698.RBG1_1C00001G0288	4.2e-35	136.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HSJS3_k127_2903463_42	1232410.KI421426_gene1513	1.944e-39	165.0	2C4IE@1|root,30ERP@2|Bacteria,1RG2Q@1224|Proteobacteria,42S4W@68525|delta/epsilon subdivisions,2WND7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2903463_36	264732.Moth_0146	2.542e-53	197.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,42FD2@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HSJS3_k127_2903463_44	867903.ThesuDRAFT_01585	5.291e-34	141.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WCNE@538999|Clostridiales incertae sedis	186801|Clostridia	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HSJS3_k127_2903463_39	1121930.AQXG01000002_gene2035	8.346e-52	194.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HSJS3_k127_2903463_13	861299.J421_3157	3.029e-127	419.0	COG0438@1|root,COG0438@2|Bacteria,1ZT2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_2903463_30	867903.ThesuDRAFT_00174	8.775e-64	240.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WCHJ@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HSJS3_k127_2903463_18	338963.Pcar_1304	4.158e-103	366.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,43T6C@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HSJS3_k127_2903463_33	379066.GAU_1562	1.861e-58	212.0	COG0084@1|root,COG0084@2|Bacteria,1ZST0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HSJS3_k127_2903463_28	1125863.JAFN01000001_gene1341	6.065e-68	243.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HSJS3_k127_2903463_12	861299.J421_3192	7.264e-132	440.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HSJS3_k127_2903463_52	439235.Dalk_5083	0.0007513	51.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria	1224|Proteobacteria	P	PFAM Phosphate-selective porin O	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
HSJS3_k127_2903463_45	1536772.R70723_16250	2.919e-20	98.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HGB5@91061|Bacilli,26RSX@186822|Paenibacillaceae	91061|Bacilli	T	Heme response regulator HssR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS3_k127_2903463_48	546271.Selsp_1867	1.029e-11	73.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
HSJS3_k127_2941801_3	1192034.CAP_2782	1.407e-50	186.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria,2YYUX@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme C-terminal domain	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
HSJS3_k127_2941801_5	379066.GAU_0210	9.029e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,1ZV8Z@142182|Gemmatimonadetes	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
HSJS3_k127_2941801_7	326424.FRAAL2823	5.703e-07	61.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS3_k127_2941801_4	379066.GAU_0209	3.299e-31	137.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS3_k127_2941801_0	502025.Hoch_5093	1.236e-72	256.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_2941801_2	402626.Rpic_3832	2.619e-55	209.0	COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2VM6S@28216|Betaproteobacteria,1K3I3@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	abmB	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.30	ko:K00019,ko:K07535	ko00072,ko00362,ko00650,ko01100,ko01120,ko01220,map00072,map00362,map00650,map01100,map01120,map01220	M00088,M00540	R01361,R05582	RC00117,RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
HSJS3_k127_2941801_6	1120983.KB894572_gene3012	1.051e-30	136.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HSJS3_k127_2941801_1	1089545.KB913037_gene2275	1.188e-67	237.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA5	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS3_k127_2944754_2	1128421.JAGA01000001_gene2365	3.927e-86	300.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
HSJS3_k127_2944754_4	861299.J421_4371	1.383e-82	288.0	COG1215@1|root,COG1215@2|Bacteria,1ZU0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 21	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HSJS3_k127_2944754_5	696281.Desru_1268	2.273e-37	147.0	COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,24KA0@186801|Clostridia,2621J@186807|Peptococcaceae	186801|Clostridia	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
HSJS3_k127_2944754_1	1128421.JAGA01000003_gene3228	6.11e-87	299.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_2944754_7	1379270.AUXF01000001_gene2471	4.289e-15	81.0	2FDUV@1|root,345VG@2|Bacteria,1ZTXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2944754_3	448385.sce2577	1.156e-85	289.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,2YWKZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
HSJS3_k127_2944754_6	861299.J421_4367	1.028e-32	137.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HSJS3_k127_2944754_0	945713.IALB_1882	1.435e-127	417.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
HSJS3_k127_2944754_8	1166018.FAES_3381	6.234e-15	85.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HSJS3_k127_2949678_1	379066.GAU_1736	5.971e-93	310.0	COG0047@1|root,COG0047@2|Bacteria,1ZTF8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HSJS3_k127_2949678_0	861299.J421_3380	3.132e-233	733.0	COG0046@1|root,COG0046@2|Bacteria,1ZT8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HSJS3_k127_2955812_1	1123073.KB899241_gene2922	8.946e-162	515.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1S1KH@1236|Gammaproteobacteria,1X3PX@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutaryl-7-ACA acylase	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HSJS3_k127_2955812_2	526227.Mesil_0734	1.744e-106	357.0	COG3181@1|root,COG3181@2|Bacteria,1WJNT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
HSJS3_k127_2955812_8	869210.Marky_0165	8.154e-13	76.0	2CQ1K@1|root,330SJ@2|Bacteria,1WKKB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
HSJS3_k127_2955812_0	649638.Trad_0128	5.851e-205	654.0	COG3333@1|root,COG3333@2|Bacteria,1WIRN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
HSJS3_k127_2955812_4	518766.Rmar_0728	2.178e-58	211.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1FJ6B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
HSJS3_k127_2955812_6	349521.HCH_00750	1.012e-32	147.0	COG2982@1|root,COG2982@2|Bacteria,1P6EN@1224|Proteobacteria,1S1EC@1236|Gammaproteobacteria,1XKNN@135619|Oceanospirillales	135619|Oceanospirillales	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2955812_7	96561.Dole_0797	4.207e-30	125.0	COG3216@1|root,COG3216@2|Bacteria,1N1Q6@1224|Proteobacteria,42VQP@68525|delta/epsilon subdivisions,2WRUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2062
HSJS3_k127_2955812_5	472759.Nhal_3328	5.605e-56	211.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXFS@135613|Chromatiales	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HSJS3_k127_2955812_3	648996.Theam_1289	1.162e-75	266.0	COG0463@1|root,COG0463@2|Bacteria,2G3VF@200783|Aquificae	200783|Aquificae	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HSJS3_k127_295916_1	1379270.AUXF01000007_gene950	4.672e-95	322.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1ZU8B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_CBB3
HSJS3_k127_295916_4	1255043.TVNIR_3648	2.798e-18	91.0	COG2319@1|root,COG2319@2|Bacteria,1QZ0Z@1224|Proteobacteria,1T3ZB@1236|Gammaproteobacteria,1X2UI@135613|Chromatiales	135613|Chromatiales	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HSJS3_k127_295916_2	391625.PPSIR1_29518	7.838e-39	159.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42S9C@68525|delta/epsilon subdivisions,2WM4G@28221|Deltaproteobacteria,2YU8Y@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	dlhH2	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
HSJS3_k127_295916_3	68570.DC74_3322	7.475e-37	148.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
HSJS3_k127_295916_0	861299.J421_2374	1.237e-95	326.0	COG0624@1|root,COG0624@2|Bacteria,1ZSZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HSJS3_k127_2981414_8	234267.Acid_0469	2.894e-24	109.0	COG1506@1|root,COG1506@2|Bacteria,3Y3DT@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
HSJS3_k127_2981414_9	402881.Plav_2200	4.303e-11	69.0	COG3409@1|root,COG3409@2|Bacteria,1NP3I@1224|Proteobacteria,2UM8V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2981414_0	1379270.AUXF01000001_gene2303	1.112e-176	579.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1ZUB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
HSJS3_k127_2981414_7	1379270.AUXF01000001_gene2302	3.611e-46	183.0	COG4249@1|root,COG4249@2|Bacteria,1ZUQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2981414_2	1379270.AUXF01000001_gene2301	1.852e-136	481.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1ZUF5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2981414_6	379066.GAU_3100	1.408e-57	210.0	29X7K@1|root,30IWU@2|Bacteria,1ZUTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
HSJS3_k127_2981414_3	379066.GAU_3101	1.659e-135	440.0	COG0714@1|root,COG0714@2|Bacteria,1ZUSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS3_k127_2981414_4	1267534.KB906756_gene96	2.317e-83	286.0	COG1721@1|root,COG1721@2|Bacteria,3Y5XW@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS3_k127_2981414_5	379066.GAU_3103	2.312e-79	291.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,1ZUB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
HSJS3_k127_2981414_1	379066.GAU_3104	4.628e-147	503.0	COG1196@1|root,COG1196@2|Bacteria,1ZU8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3002926_0	1123073.KB899241_gene2922	2.997e-129	423.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1S1KH@1236|Gammaproteobacteria,1X3PX@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutaryl-7-ACA acylase	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HSJS3_k127_3002926_1	714943.Mucpa_4857	2.778e-76	269.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HSJS3_k127_3002926_2	861299.J421_3626	1.39e-51	199.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3002926_4	1278073.MYSTI_06129	1.689e-16	88.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,42XMG@68525|delta/epsilon subdivisions,2WSJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
HSJS3_k127_3002926_3	1379270.AUXF01000003_gene3824	3.261e-21	97.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
HSJS3_k127_3005986_0	1121405.dsmv_1337	6.28e-154	500.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2WIVJ@28221|Deltaproteobacteria,2MIV0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
HSJS3_k127_3005986_1	266117.Rxyl_2372	5.138e-67	231.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4CQ9H@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
HSJS3_k127_3041612_0	379066.GAU_2152	1.38e-274	854.0	COG0481@1|root,COG0481@2|Bacteria,1ZTGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,LepA_C
HSJS3_k127_3041612_28	671143.DAMO_1641	4.83e-35	147.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	rfaF	-	2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28	ko:K02841,ko:K02843,ko:K02849,ko:K03271,ko:K03272,ko:K03273	ko00540,ko01100,map00540,map01100	M00064,M00080	R05644,R05645,R05646,R05647,R09768,R09769,R09771	RC00002,RC00017,RC00078,RC00434	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
HSJS3_k127_3041612_9	861299.J421_3753	2.196e-113	377.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HSJS3_k127_3041612_13	379066.GAU_2155	4.449e-86	305.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3041612_17	861299.J421_3755	4.536e-76	265.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3041612_31	861299.J421_3756	4.411e-25	118.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3041612_32	858215.Thexy_0839	5.007e-19	91.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia,42GUA@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NifU
HSJS3_k127_3041612_12	1379270.AUXF01000003_gene3479	5.755e-97	331.0	COG0489@1|root,COG0489@2|Bacteria,1ZSW7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HSJS3_k127_3041612_25	861299.J421_3911	1.69e-50	192.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
HSJS3_k127_3041612_36	861299.J421_3909	0.0002745	52.0	2F9A9@1|root,341MC@2|Bacteria,1ZU0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3041612_19	861299.J421_3908	2.022e-65	230.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_3041612_15	861299.J421_3907	9.916e-80	279.0	COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HSJS3_k127_3041612_23	237368.SCABRO_00905	7.224e-53	207.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_3041612_7	243231.GSU0927	8.535e-116	396.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,43TJ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_3041612_20	1121468.AUBR01000058_gene880	2.234e-62	225.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,42G5U@68295|Thermoanaerobacterales	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HSJS3_k127_3041612_29	1030157.AFMP01000043_gene1709	2.873e-33	146.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2UCR7@28211|Alphaproteobacteria,2K5MQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HSJS3_k127_3041612_8	546271.Selsp_1021	9.656e-115	388.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HSJS3_k127_3041612_14	390989.JOEG01000001_gene5219	2.19e-83	288.0	COG0501@1|root,COG0501@2|Bacteria,2GKJQ@201174|Actinobacteria,4DBRM@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HSJS3_k127_3041612_5	861299.J421_3896	3.479e-140	458.0	COG0626@1|root,COG0626@2|Bacteria,1ZT9F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
HSJS3_k127_3041612_6	379066.GAU_2428	7.236e-139	456.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HSJS3_k127_3041612_1	861299.J421_3893	4.085e-241	764.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HSJS3_k127_3041612_26	1519464.HY22_13900	4.204e-50	189.0	COG1490@1|root,COG1490@2|Bacteria,1FE5M@1090|Chlorobi	1090|Chlorobi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HSJS3_k127_3041612_24	1379270.AUXF01000003_gene3504	8.333e-53	200.0	COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HSJS3_k127_3041612_4	159087.Daro_1922	1.304e-165	536.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria,2KV0H@206389|Rhodocyclales	206389|Rhodocyclales	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HSJS3_k127_3041612_30	1379270.AUXF01000004_gene3076	7.067e-27	115.0	COG2332@1|root,COG2332@2|Bacteria,1ZTNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
HSJS3_k127_3041612_3	861299.J421_2742	1.995e-200	645.0	COG1138@1|root,COG1138@2|Bacteria,1ZTBY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
HSJS3_k127_3041612_33	379066.GAU_0822	2.86e-07	59.0	29W2Z@1|root,30HMM@2|Bacteria,1ZTXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3041612_21	1125863.JAFN01000001_gene3012	7.252e-61	220.0	COG1131@1|root,COG1131@2|Bacteria,1RGM1@1224|Proteobacteria,43ADE@68525|delta/epsilon subdivisions,2X5TA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
HSJS3_k127_3041612_27	1125863.JAFN01000001_gene3011	5.562e-38	152.0	COG2386@1|root,COG2386@2|Bacteria,1QF23@1224|Proteobacteria,42RAM@68525|delta/epsilon subdivisions,2WMS1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
HSJS3_k127_3041612_22	309801.trd_1217	7.289e-55	211.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi,27Y6D@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
HSJS3_k127_3041612_35	1492922.GY26_18315	8.94e-07	63.0	COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,1RN4J@1236|Gammaproteobacteria,1J64Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	salt-induced outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
HSJS3_k127_3041612_11	379066.GAU_1232	3.313e-105	359.0	COG1946@1|root,COG1946@2|Bacteria,1ZUM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase-like superfamily	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
HSJS3_k127_3041612_10	1047013.AQSP01000110_gene67	1.975e-112	374.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HSJS3_k127_3041612_34	379066.GAU_2229	5.698e-07	59.0	2960H@1|root,2ZTB5@2|Bacteria,1ZU7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3041612_18	861299.J421_3527	1.319e-66	233.0	COG0468@1|root,COG0468@2|Bacteria,1ZT78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HSJS3_k127_3041612_16	1414720.CBYM010000016_gene2890	1.484e-79	269.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,36DUE@31979|Clostridiaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HSJS3_k127_3041612_2	1211114.ALIP01000113_gene866	5.703e-226	721.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1X3MQ@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HSJS3_k127_3094678_1	1236902.ANAS01000001_gene1927	1.729e-118	401.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4EI2I@85012|Streptosporangiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
HSJS3_k127_3094678_3	335541.Swol_0785	1.445e-80	287.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,42K9F@68298|Syntrophomonadaceae	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
HSJS3_k127_3094678_0	246194.CHY_0733	1.682e-164	533.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,42J1I@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	-	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
HSJS3_k127_3094678_2	1191523.MROS_0895	6.649e-115	386.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	bamW	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
HSJS3_k127_3107068_0	1267535.KB906767_gene2436	3.603e-214	688.0	COG0578@1|root,COG0578@2|Bacteria,3Y2YF@57723|Acidobacteria,2JI40@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HSJS3_k127_3107068_2	518766.Rmar_1847	3.478e-74	263.0	28PR2@1|root,2ZCCZ@2|Bacteria,4NMVK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3107068_4	1396141.BATP01000045_gene1849	4.097e-15	80.0	2DRAF@1|root,33AYA@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
HSJS3_k127_3107068_1	33876.JNXY01000009_gene8908	1.67e-109	389.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulator	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
HSJS3_k127_3107068_3	633149.Bresu_1575	3.632e-43	176.0	COG2010@1|root,COG2010@2|Bacteria,1N0EF@1224|Proteobacteria,2UCVE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3107068_6	401053.AciPR4_2427	2.017e-06	61.0	COG3866@1|root,COG5492@1|root,COG3866@2|Bacteria,COG5492@2|Bacteria,3Y3VF@57723|Acidobacteria,2JHRK@204432|Acidobacteriia	204432|Acidobacteriia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HSJS3_k127_3107068_5	1379270.AUXF01000002_gene1160	9.422e-11	75.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HSJS3_k127_3111834_9	309807.SRU_2647	8.555e-114	382.0	28I15@1|root,2Z85U@2|Bacteria,4NIUE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3111834_12	309807.SRU_2646	1.326e-95	328.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HSJS3_k127_3111834_8	309807.SRU_2646	1.173e-121	411.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HSJS3_k127_3111834_1	1313301.AUGC01000012_gene1308	2.684e-227	717.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
HSJS3_k127_3111834_15	309801.trd_0794	3.927e-79	274.0	COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi,27XIZ@189775|Thermomicrobia	189775|Thermomicrobia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
HSJS3_k127_3111834_10	309807.SRU_2273	2.507e-113	385.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,Na_H_Exchanger,TrkA_N
HSJS3_k127_3111834_5	309807.SRU_2272	5.571e-132	445.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,1FJIA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
HSJS3_k127_3111834_17	502025.Hoch_3068	1.387e-60	220.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WJX5@28221|Deltaproteobacteria,2YZM2@29|Myxococcales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	cfa1	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iAF987.Gmet_2187	CMAS
HSJS3_k127_3111834_14	861299.J421_6122	1.126e-80	284.0	28P8D@1|root,33QB6@2|Bacteria,1ZSQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
HSJS3_k127_3111834_0	861299.J421_6121	2.418e-310	983.0	COG1629@1|root,COG4771@2|Bacteria,1ZT9M@142182|Gemmatimonadetes	861299.J421_6121|-	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3111834_11	1379270.AUXF01000003_gene3634	1.853e-104	353.0	COG2234@1|root,COG2234@2|Bacteria,1ZUGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HSJS3_k127_3111834_2	1379270.AUXF01000002_gene1544	5.143e-220	698.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HSJS3_k127_3111834_6	234267.Acid_4580	1.486e-131	439.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	dap	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Beta-lactamase,DAP_B
HSJS3_k127_3111834_7	1124780.ANNU01000059_gene866	1.578e-123	417.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47K06@768503|Cytophagia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HSJS3_k127_3111834_23	338966.Ppro_3073	8.375e-09	62.0	2EDV0@1|root,337Q4@2|Bacteria,1NFM4@1224|Proteobacteria,43264@68525|delta/epsilon subdivisions,2WXFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3111834_3	322710.Avin_20870	5.713e-196	627.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
HSJS3_k127_3111834_22	1401065.HMPREF2130_01235	1.028e-09	62.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2VXNN@28216|Betaproteobacteria,3T4ZA@506|Alcaligenaceae	28216|Betaproteobacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
HSJS3_k127_3111834_18	981369.JQMJ01000001_gene6692	2.446e-51	192.0	COG2761@1|root,COG2761@2|Bacteria,2GNBC@201174|Actinobacteria,2NIM7@228398|Streptacidiphilus	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
HSJS3_k127_3111834_13	768066.HELO_2552	4.036e-84	291.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1XH9Y@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HSJS3_k127_3111834_19	330214.NIDE3508	4.645e-51	190.0	28N6F@1|root,2ZBBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3111834_21	321327.CYA_0560	2.37e-10	66.0	COG1950@1|root,COG1950@2|Bacteria,1G835@1117|Cyanobacteria,1H1UR@1129|Synechococcus	1117|Cyanobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
HSJS3_k127_3111834_20	1294143.H681_06105	1.066e-15	78.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,TPR_2
HSJS3_k127_3111834_16	1123377.AUIV01000020_gene2478	3.33e-66	233.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1X6M0@135614|Xanthomonadales	135614|Xanthomonadales	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
HSJS3_k127_3111834_4	1123377.AUIV01000020_gene2477	3.441e-193	623.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,1RQUG@1236|Gammaproteobacteria,1X59Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
HSJS3_k127_3130751_0	926550.CLDAP_23540	1.902e-260	842.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
HSJS3_k127_3130751_2	566466.NOR53_446	4.434e-59	233.0	COG1680@1|root,COG4319@1|root,COG1680@2|Bacteria,COG4319@2|Bacteria,1P3SQ@1224|Proteobacteria,1S64P@1236|Gammaproteobacteria,1J7VV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440
HSJS3_k127_3130751_3	1248916.ANFY01000017_gene1475	1.146e-44	181.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,2KDZF@204457|Sphingomonadales	204457|Sphingomonadales	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HSJS3_k127_3130751_1	1038859.AXAU01000004_gene4428	5.862e-72	252.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
HSJS3_k127_3130751_4	633149.Bresu_1073	2.698e-27	118.0	COG4625@1|root,COG4625@2|Bacteria,1N0QY@1224|Proteobacteria,2VGGQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3145809_5	338963.Pcar_1300	2.495e-09	68.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,43US2@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HSJS3_k127_3145809_4	1033802.SSPSH_002399	8.179e-32	138.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HSJS3_k127_3145809_3	880072.Desac_1392	8.372e-46	173.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2X6DV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HSJS3_k127_3145809_6	1122179.KB890424_gene3634	1.611e-08	66.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1ITAU@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HSJS3_k127_3145809_0	861299.J421_3143	5.202e-162	520.0	COG0044@1|root,COG0044@2|Bacteria,1ZT4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HSJS3_k127_3145809_1	861299.J421_3142	2.087e-154	496.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HSJS3_k127_3145809_2	379066.GAU_1514	1.156e-49	183.0	COG2065@1|root,COG2065@2|Bacteria,1ZTHG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HSJS3_k127_327366_11	1111069.TCCBUS3UF1_530	2.088e-39	151.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
HSJS3_k127_327366_13	1267533.KB906733_gene3563	1.852e-20	107.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
HSJS3_k127_327366_8	861299.J421_2851	1.04e-55	218.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	BTAD
HSJS3_k127_327366_17	357808.RoseRS_1915	1.378e-10	73.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
HSJS3_k127_327366_0	861299.J421_2569	6.648e-144	466.0	COG0343@1|root,COG0343@2|Bacteria,1ZSRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HSJS3_k127_327366_14	485915.Dret_0845	4.792e-17	95.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MCSM@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HSJS3_k127_327366_10	684719.HIMB114_00012750	5.114e-42	167.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,4BQGS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630	-	R00653	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	Pep_deformylase
HSJS3_k127_327366_2	861299.J421_2566	3.649e-101	339.0	COG0223@1|root,COG0223@2|Bacteria,1ZTE5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HSJS3_k127_327366_12	134676.ACPL_817	7.61e-29	124.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4DADP@85008|Micromonosporales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
HSJS3_k127_327366_16	1007103.AFHW01000170_gene2552	1.201e-11	67.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,4HR3T@91061|Bacilli,26ZWR@186822|Paenibacillaceae	91061|Bacilli	H	Thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HSJS3_k127_327366_3	1162668.LFE_0106	8.883e-89	301.0	COG2022@1|root,COG2022@2|Bacteria,3J0EI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
HSJS3_k127_327366_4	379066.GAU_0623	6.549e-81	291.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
HSJS3_k127_327366_15	1125718.HMPREF1318_0369	3.842e-15	89.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4D3IX@85005|Actinomycetales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HSJS3_k127_327366_9	861299.J421_2562	3.555e-45	170.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS3_k127_327366_18	882.DVU_1281	9.536e-07	60.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MC38@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
HSJS3_k127_327366_1	379066.GAU_0619	4.222e-102	358.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HSJS3_k127_327366_6	379066.GAU_0618	8.71e-60	216.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HSJS3_k127_327366_5	472759.Nhal_2909	1.674e-61	223.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,1S5S8@1236|Gammaproteobacteria,1WYBG@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HSJS3_k127_327366_7	861299.J421_2544	2.357e-56	216.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HSJS3_k127_3291596_2	379066.GAU_1377	8.309e-43	162.0	COG2050@1|root,COG2050@2|Bacteria,1ZV1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
HSJS3_k127_3291596_1	926560.KE387023_gene2647	3.158e-47	186.0	COG0596@1|root,COG0596@2|Bacteria,1WN2Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3291596_3	638303.Thal_1500	6.148e-09	63.0	COG0568@1|root,COG0568@2|Bacteria,2G3PM@200783|Aquificae	200783|Aquificae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS3_k127_3291596_0	1121104.AQXH01000001_gene2028	7.583e-132	435.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HSJS3_k127_3360657_2	388413.ALPR1_14609	9.638e-22	111.0	arCOG07533@1|root,2ZF5I@2|Bacteria,4NMWZ@976|Bacteroidetes,47S9K@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
HSJS3_k127_3360657_0	749927.AMED_2015	7.77e-93	315.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
HSJS3_k127_3360657_1	391625.PPSIR1_29955	4.451e-49	181.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
HSJS3_k127_3415881_1	379066.GAU_0969	3.779e-14	76.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HSJS3_k127_3415881_0	379066.GAU_0968	5.757e-110	370.0	COG3550@1|root,COG3550@2|Bacteria	2|Bacteria	S	kinase activity	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
HSJS3_k127_3415881_2	278963.ATWD01000001_gene1196	1.802e-05	53.0	COG0577@1|root,COG0577@2|Bacteria	278963.ATWD01000001_gene1196|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3546754_4	379066.GAU_1144	6.649e-67	242.0	COG0577@1|root,COG0577@2|Bacteria,1ZUN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_3546754_1	861299.J421_2901	3.486e-104	358.0	COG0577@1|root,COG0577@2|Bacteria,1ZSU3@142182|Gemmatimonadetes	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_3546754_2	1379270.AUXF01000005_gene458	1.824e-98	340.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
HSJS3_k127_3546754_6	517418.Ctha_0641	1.406e-21	110.0	COG1538@1|root,COG1538@2|Bacteria,1FDGZ@1090|Chlorobi	1090|Chlorobi	MU	PFAM outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HSJS3_k127_3546754_7	861299.J421_2905	2.274e-19	97.0	2FH8I@1|root,3492W@2|Bacteria,1ZTXF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3546754_5	861299.J421_2906	3.915e-44	171.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_3546754_3	1379270.AUXF01000005_gene461	9.848e-94	348.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HSJS3_k127_3546754_0	1382306.JNIM01000001_gene1966	3.663e-111	367.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
HSJS3_k127_3647100_2	867903.ThesuDRAFT_01015	1.002e-17	84.0	COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,247UT@186801|Clostridia	186801|Clostridia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HSJS3_k127_3647100_0	861299.J421_2931	1.144e-75	274.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
HSJS3_k127_3647100_1	208444.JNYY01000009_gene3606	2.833e-28	116.0	COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria,4E19E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_3784044_9	28042.GU90_17710	6.932e-31	129.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4E2W5@85010|Pseudonocardiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HSJS3_k127_3784044_11	880073.Calab_2051	4.05e-22	104.0	COG0228@1|root,COG0228@2|Bacteria,2NPWN@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HSJS3_k127_3784044_5	234267.Acid_5931	1.01e-60	219.0	COG0730@1|root,COG0730@2|Bacteria,3Y4IM@57723|Acidobacteria	57723|Acidobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HSJS3_k127_3784044_4	379066.GAU_2187	6.744e-69	239.0	COG0431@1|root,COG0431@2|Bacteria,1ZUYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
HSJS3_k127_3784044_1	1278073.MYSTI_00528	9.916e-176	563.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YWP2@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HSJS3_k127_3784044_6	1047013.AQSP01000107_gene2087	1.358e-44	176.0	COG0668@1|root,COG0668@2|Bacteria,2NPVN@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	mscS_1	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	BON,MS_channel
HSJS3_k127_3784044_2	379066.GAU_2347	8.95e-158	509.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HSJS3_k127_3784044_10	438753.AZC_3668	1.944e-28	121.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,3EZKM@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	MA20_31615	-	-	-	-	-	-	-	-	-	-	-	CBS
HSJS3_k127_3784044_7	1123368.AUIS01000035_gene81	2.17e-38	150.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
HSJS3_k127_3784044_0	861299.J421_0786	1.313e-274	871.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HSJS3_k127_3784044_12	1411123.JQNH01000001_gene3917	1.331e-07	55.0	2EPB0@1|root,33GXS@2|Bacteria,1NHGH@1224|Proteobacteria,2UMMF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3784044_3	861299.J421_5896	1.027e-150	509.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_5896|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3784044_8	1278073.MYSTI_07863	3.764e-31	127.0	COG1695@1|root,COG1695@2|Bacteria,1PMEN@1224|Proteobacteria,43544@68525|delta/epsilon subdivisions,2WZF7@28221|Deltaproteobacteria,2Z209@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_397050_0	1121104.AQXH01000004_gene27	0.0	1133.0	COG4447@1|root,COG4447@2|Bacteria,4P16I@976|Bacteroidetes,1IWTV@117747|Sphingobacteriia	976|Bacteroidetes	G	SPTR Glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HSJS3_k127_397050_2	290315.Clim_2334	1.126e-107	363.0	COG0498@1|root,COG0498@2|Bacteria,1FDCN@1090|Chlorobi	1090|Chlorobi	H	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
HSJS3_k127_397050_4	861299.J421_1590	9.773e-45	180.0	COG0083@1|root,COG0083@2|Bacteria	2|Bacteria	E	homoserine kinase activity	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620	GHMP_kinases_C,GHMP_kinases_N
HSJS3_k127_397050_1	880073.Calab_2482	1.989e-128	425.0	COG0534@1|root,COG0534@2|Bacteria,2NPFE@2323|unclassified Bacteria	2|Bacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
HSJS3_k127_397050_7	1445613.JALM01000019_gene5723	1.116e-05	57.0	2DBIT@1|root,2Z9GU@2|Bacteria,2GN9J@201174|Actinobacteria,4DXD1@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM carotene biosynthesis associated membrane protein	mptA	GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
HSJS3_k127_397050_6	290397.Adeh_2899	2.103e-09	70.0	COG0823@1|root,COG0823@2|Bacteria,1NKG5@1224|Proteobacteria	1224|Proteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HSJS3_k127_397050_9	1408418.JNJH01000020_gene967	4.781e-05	50.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2JV8U@204441|Rhodospirillales	204441|Rhodospirillales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HSJS3_k127_397050_11	1247024.JRLH01000002_gene196	0.0001024	46.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria,1SHSY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_397050_12	1150626.PHAMO_320002	0.0001133	44.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,2JTWP@204441|Rhodospirillales	204441|Rhodospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HSJS3_k127_397050_13	1197906.CAJQ02000003_gene3219	0.0001562	45.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HSJS3_k127_397050_8	1423807.BACO01000097_gene2535	1.163e-05	54.0	2DRA2@1|root,33AVQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_397050_15	59538.XP_005979423.1	0.0005322	47.0	COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3BEEV@33208|Metazoa,3CRTP@33213|Bilateria,4801S@7711|Chordata,492UT@7742|Vertebrata,3JDRF@40674|Mammalia,4J43Y@91561|Cetartiodactyla	33208|Metazoa	C	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
HSJS3_k127_397050_5	1283283.ATXA01000001_gene422	4.104e-29	129.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,CHRD,CarboxypepD_reg,DUF3455,G8,HemolysinCabind,Prenyltrans
HSJS3_k127_397050_3	861299.J421_4338	1.171e-63	231.0	COG0457@1|root,COG0457@2|Bacteria,1ZU8U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
HSJS3_k127_4043391_6	925409.KI911562_gene2345	8.352e-38	145.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HSJS3_k127_4043391_1	570967.JMLV01000006_gene206	3.495e-83	288.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HSJS3_k127_4043391_9	1236541.BALL01000036_gene3656	3.311e-08	67.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,2Q9X4@267890|Shewanellaceae	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	ShlB
HSJS3_k127_4043391_2	309807.SRU_2423	1.487e-74	273.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1FJQP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
HSJS3_k127_4043391_10	102129.Lepto7375DRAFT_2177	0.000432	51.0	COG1442@1|root,COG1442@2|Bacteria,1G8UX@1117|Cyanobacteria,1HD4F@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
HSJS3_k127_4043391_0	1444309.JAQG01000017_gene776	3.49e-86	311.0	COG2866@1|root,COG2866@2|Bacteria,1UZ9X@1239|Firmicutes,4HW2F@91061|Bacilli	91061|Bacilli	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HSJS3_k127_4043391_3	879243.Poras_0727	1.604e-66	252.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,2FMUK@200643|Bacteroidia,22VY0@171551|Porphyromonadaceae	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HSJS3_k127_4043391_4	1150864.MILUP08_41270	3.618e-47	196.0	COG0438@1|root,COG0438@2|Bacteria,2IDYB@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HSJS3_k127_4043391_5	935261.JAGL01000054_gene643	2.771e-41	177.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,1QVAX@1224|Proteobacteria,2TWQU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Glycos_transf_2
HSJS3_k127_4043391_7	290397.Adeh_2641	3.417e-23	117.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,42PY5@68525|delta/epsilon subdivisions,2WIU8@28221|Deltaproteobacteria,2YVJ5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	tuaH	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
HSJS3_k127_4043391_8	861299.J421_3786	3.683e-13	70.0	COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HSJS3_k127_4055614_14	1382356.JQMP01000004_gene149	1.359e-17	85.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,27Y9H@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
HSJS3_k127_4055614_13	326427.Cagg_3411	6.171e-28	117.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi,377N3@32061|Chloroflexia	32061|Chloroflexia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HSJS3_k127_4055614_16	644282.Deba_2004	7.42e-13	72.0	COG2608@1|root,COG2608@2|Bacteria,1PUDD@1224|Proteobacteria,42XJ7@68525|delta/epsilon subdivisions,2WSKI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HSJS3_k127_4055614_3	926569.ANT_12590	1.604e-232	742.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HSJS3_k127_4055614_19	322710.Avin_01040	7.617e-05	54.0	2AEBT@1|root,31468@2|Bacteria,1RC39@1224|Proteobacteria,1S7QQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4055614_7	1121918.ARWE01000001_gene2577	4.164e-75	258.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,43SE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS3_k127_4055614_10	1198452.Jab_2c15020	1.446e-57	223.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,2VI30@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HAMP,HATPase_c,HisKA
HSJS3_k127_4055614_8	991905.SL003B_0612	1.268e-64	233.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,2TQPX@28211|Alphaproteobacteria,4BSFG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
HSJS3_k127_4055614_11	1379270.AUXF01000007_gene949	1.008e-38	153.0	COG0723@1|root,COG0723@2|Bacteria,1ZUKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
HSJS3_k127_4055614_0	1123368.AUIS01000008_gene2263	0.0	1216.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,2NCMA@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
HSJS3_k127_4055614_5	379066.GAU_1315	2.64e-77	290.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4,YtkA
HSJS3_k127_4055614_9	671143.DAMO_0961	3.828e-59	224.0	COG1538@1|root,COG1538@2|Bacteria,2NPI8@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
HSJS3_k127_4055614_12	379066.GAU_1320	6.809e-33	135.0	COG4319@1|root,COG4319@2|Bacteria,1ZV6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4055614_18	1123320.KB889730_gene5928	1.568e-08	63.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
HSJS3_k127_4055614_2	404589.Anae109_4267	4.724e-244	778.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42PNF@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Multicopper oxidase	copA	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HSJS3_k127_4055614_6	404589.Anae109_4266	1.313e-75	261.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,42SFY@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Copper resistance protein B precursor (CopB)	-	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
HSJS3_k127_4055614_15	913325.N799_11570	2.947e-16	85.0	COG4319@1|root,COG4319@2|Bacteria,1QFY7@1224|Proteobacteria,1TD9Q@1236|Gammaproteobacteria,1XACW@135614|Xanthomonadales	135614|Xanthomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
HSJS3_k127_4055614_4	1089550.ATTH01000001_gene1182	8.59e-150	483.0	COG0701@1|root,COG0701@2|Bacteria,4NI2E@976|Bacteroidetes	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
HSJS3_k127_4055614_1	1211115.ALIQ01000030_gene2231	1.617e-255	798.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3NAW2@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	YHS domain	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
HSJS3_k127_4058869_2	1379698.RBG1_1C00001G0393	1.249e-105	355.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
HSJS3_k127_4058869_3	1379270.AUXF01000005_gene686	4.643e-91	328.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_4058869_0	861299.J421_3071	1.627e-140	461.0	COG0769@1|root,COG0769@2|Bacteria,1ZSS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_4058869_1	861299.J421_3070	8.24e-116	403.0	COG0768@1|root,COG0768@2|Bacteria,1ZSYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
HSJS3_k127_4058869_4	379066.GAU_1420	6.132e-85	302.0	COG0275@1|root,COG0275@2|Bacteria,1ZT4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HSJS3_k127_4058869_5	246194.CHY_2079	1.097e-21	99.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,42GA2@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HSJS3_k127_4067188_3	861299.J421_2656	1.713e-131	425.0	COG0587@1|root,COG0587@2|Bacteria,1ZT8N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HSJS3_k127_4067188_8	1379270.AUXF01000001_gene2190	4.105e-34	138.0	2A22Y@1|root,30QD2@2|Bacteria,1ZUZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4067188_5	1122179.KB890436_gene1350	1.361e-120	398.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,1IQ6Y@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
HSJS3_k127_4067188_11	518766.Rmar_1051	5.645e-13	80.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,1FJ29@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
HSJS3_k127_4067188_0	649638.Trad_1981	5.655e-234	743.0	COG0339@1|root,COG0339@2|Bacteria,1WM8B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase family M3	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
HSJS3_k127_4067188_2	1278073.MYSTI_07864	4.463e-161	542.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_4067188_10	861299.J421_6140	4.45e-20	93.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_4067188_4	379066.GAU_3326	2.131e-130	429.0	COG2081@1|root,COG2081@2|Bacteria,1ZUAT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HSJS3_k127_4067188_9	290318.Cvib_1767	6.679e-27	124.0	COG0705@1|root,COG0705@2|Bacteria,1FDF1@1090|Chlorobi	1090|Chlorobi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HSJS3_k127_4067188_1	869210.Marky_1927	2.677e-168	543.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
HSJS3_k127_4067188_7	861299.J421_0095	6.545e-71	247.0	COG1739@1|root,COG1739@2|Bacteria,1ZTND@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1949)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
HSJS3_k127_4067188_6	32049.SYNPCC7002_A2163	3.481e-96	323.0	COG0668@1|root,COG0668@2|Bacteria,1G2IB@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Mechanosensitive ion channel	-	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
HSJS3_k127_4074536_3	1134912.AJTV01000056_gene3811	2.023e-29	123.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,36X6A@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Amino acid kinase family	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HSJS3_k127_4074536_1	748658.KB907320_gene879	1.226e-81	284.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1WWVX@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HSJS3_k127_4074536_0	379066.GAU_0971	7.586e-90	311.0	COG1228@1|root,COG1228@2|Bacteria,1ZUSA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_4074536_2	379066.GAU_3767	3.509e-54	196.0	COG0451@1|root,COG0451@2|Bacteria,1ZUDW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NAD(P)H-binding	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
HSJS3_k127_4088647_2	324602.Caur_1068	5.023e-65	236.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,37579@32061|Chloroflexia	32061|Chloroflexia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HSJS3_k127_4088647_1	204669.Acid345_4314	2.984e-97	335.0	COG4941@1|root,COG4941@2|Bacteria,3Y42G@57723|Acidobacteria,2JM1K@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
HSJS3_k127_4088647_3	1379270.AUXF01000001_gene2271	2.274e-25	109.0	COG3795@1|root,COG3795@2|Bacteria,1ZV0M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS3_k127_4088647_0	452637.Oter_1829	4.254e-151	512.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_4088647_4	1267533.KB906734_gene4016	2.444e-15	79.0	COG1695@1|root,COG1695@2|Bacteria,3Y8CC@57723|Acidobacteria,2JP3G@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_4131997_4	926550.CLDAP_16500	2.443e-120	400.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
HSJS3_k127_4131997_5	861299.J421_3104	3.66e-87	315.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1ZSMY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
HSJS3_k127_4131997_3	379066.GAU_1454	8.589e-141	473.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HSJS3_k127_4131997_8	479436.Vpar_0886	2.676e-69	251.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4H2GA@909932|Negativicutes	909932|Negativicutes	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
HSJS3_k127_4131997_15	861299.J421_3097	2.039e-12	80.0	2EYUI@1|root,33S1Q@2|Bacteria,1ZTHR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4131997_13	555088.DealDRAFT_0904	5.595e-34	135.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,42K0G@68298|Syntrophomonadaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HSJS3_k127_4131997_10	861299.J421_3093	3.81e-68	252.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HSJS3_k127_4131997_11	861299.J421_3092	1.443e-64	230.0	COG1694@1|root,COG3956@2|Bacteria,1ZSZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
HSJS3_k127_4131997_6	861299.J421_2802	3.386e-80	280.0	COG0111@1|root,COG0111@2|Bacteria,1ZUG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
HSJS3_k127_4131997_0	379066.GAU_1447	3.318e-178	579.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HSJS3_k127_4131997_1	292459.STH1384	5.987e-178	581.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HSJS3_k127_4131997_7	1111479.AXAR01000004_gene2042	1.363e-72	256.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,2783K@186823|Alicyclobacillaceae	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HSJS3_k127_4131997_14	861299.J421_3082	1.35e-31	143.0	COG1572@1|root,COG1572@2|Bacteria,1ZSTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4131997_9	396588.Tgr7_2406	9.985e-69	250.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1WX4H@135613|Chromatiales	135613|Chromatiales	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
HSJS3_k127_4131997_2	861299.J421_3080	6.988e-147	476.0	COG0206@1|root,COG0206@2|Bacteria,1ZSNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HSJS3_k127_4131997_12	1379270.AUXF01000005_gene693	6.313e-61	218.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
HSJS3_k127_4132543_0	517418.Ctha_1886	6.504e-193	609.0	COG4147@1|root,COG4147@2|Bacteria,1FDIY@1090|Chlorobi	1090|Chlorobi	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
HSJS3_k127_4140991_3	713586.KB900536_gene634	4.287e-24	107.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
HSJS3_k127_4140991_0	880073.Calab_2482	1.969e-118	395.0	COG0534@1|root,COG0534@2|Bacteria,2NPFE@2323|unclassified Bacteria	2|Bacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
HSJS3_k127_4140991_2	861299.J421_1590	4.02e-57	211.0	COG0083@1|root,COG0083@2|Bacteria	2|Bacteria	E	homoserine kinase activity	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620	GHMP_kinases_C,GHMP_kinases_N
HSJS3_k127_4140991_1	319225.Plut_1987	8.236e-108	364.0	COG0498@1|root,COG0498@2|Bacteria,1FDCN@1090|Chlorobi	1090|Chlorobi	H	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
HSJS3_k127_4166699_19	234267.Acid_3515	2.406e-64	241.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_4166699_27	1267535.KB906767_gene2332	1.449e-24	106.0	COG1695@1|root,COG1695@2|Bacteria,3Y4WY@57723|Acidobacteria,2JJYG@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_4166699_4	379066.GAU_0638	1.208e-170	550.0	COG0745@1|root,COG0745@2|Bacteria,1ZTEW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
HSJS3_k127_4166699_6	1379270.AUXF01000004_gene3243	4.466e-144	478.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
HSJS3_k127_4166699_20	379066.GAU_2095	7.771e-57	218.0	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HSJS3_k127_4166699_21	861299.J421_2674	5.874e-56	217.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
HSJS3_k127_4166699_22	861299.J421_1980	1.937e-50	196.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
HSJS3_k127_4166699_26	861299.J421_3339	5.172e-29	124.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
HSJS3_k127_4166699_14	861299.J421_3870	1.142e-104	351.0	COG0859@1|root,COG0859@2|Bacteria,1ZT3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HSJS3_k127_4166699_29	379066.GAU_2418	2.358e-18	100.0	COG3642@1|root,COG3642@2|Bacteria,1ZTTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
HSJS3_k127_4166699_35	861299.J421_1466	7.556e-06	53.0	2A0X4@1|root,30P27@2|Bacteria,1ZUWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4166699_2	478741.JAFS01000001_gene1421	1.575e-191	612.0	COG0146@1|root,COG0146@2|Bacteria,46UMR@74201|Verrucomicrobia,37G2Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
HSJS3_k127_4166699_31	861299.J421_4201	7.775e-15	77.0	2CA00@1|root,344QM@2|Bacteria,1ZU1Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4166699_13	861299.J421_4211	1.021e-105	355.0	COG0457@1|root,COG0457@2|Bacteria,1ZSYB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
HSJS3_k127_4166699_30	1379270.AUXF01000002_gene1804	4.965e-18	96.0	2F95J@1|root,341H1@2|Bacteria,1ZTZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4166699_12	1183377.Py04_0852	1.744e-106	357.0	COG0473@1|root,arCOG01163@2157|Archaea,2XT99@28890|Euryarchaeota,242YH@183968|Thermococci	183968|Thermococci	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HSJS3_k127_4166699_8	7425.NV12952-PA	2.241e-132	434.0	COG0183@1|root,KOG1391@2759|Eukaryota,39QWG@33154|Opisthokonta,3BAQ0@33208|Metazoa,3CS5N@33213|Bilateria,41U9C@6656|Arthropoda,3SKFP@50557|Insecta,46HC3@7399|Hymenoptera	33208|Metazoa	I	Thiolase, C-terminal domain	ACAA2	GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234	2.3.1.16,2.3.1.254	ko:K07508,ko:K17972	ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212	M00085,M00087	R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko03029	-	-	-	Thiolase_C,Thiolase_N
HSJS3_k127_4166699_11	316274.Haur_1203	1.297e-107	359.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HSJS3_k127_4166699_34	379066.GAU_0668	2.613e-07	61.0	COG2207@1|root,COG2207@2|Bacteria,1ZV67@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HSJS3_k127_4166699_32	1209989.TepiRe1_1203	3.311e-10	63.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,42H3D@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HSJS3_k127_4166699_25	861299.J421_3557	3.305e-34	139.0	COG0629@1|root,COG0629@2|Bacteria,1ZTPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HSJS3_k127_4166699_18	880073.Calab_0535	1.234e-77	270.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS3_k127_4166699_17	861299.J421_2731	3.153e-80	284.0	COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HSJS3_k127_4166699_33	526227.Mesil_0055	1.995e-07	58.0	COG5512@1|root,COG5512@2|Bacteria,1WIYS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
HSJS3_k127_4166699_1	635013.TherJR_0008	4.327e-268	839.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HSJS3_k127_4166699_36	1121875.KB907549_gene1891	1.78e-05	55.0	2E3AK@1|root,32YA3@2|Bacteria,4NUYM@976|Bacteroidetes,1I4YQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4166699_10	497964.CfE428DRAFT_3487	2.435e-111	383.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
HSJS3_k127_4166699_24	1156935.QWE_00580	4.16e-40	166.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,2VBXY@28211|Alphaproteobacteria,4BI6G@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF234
HSJS3_k127_4166699_0	518766.Rmar_2149	8.585e-304	947.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
HSJS3_k127_4166699_16	1047013.AQSP01000120_gene969	4.286e-91	338.0	COG3857@1|root,COG3857@2|Bacteria,2NQ4T@2323|unclassified Bacteria	2|Bacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
HSJS3_k127_4166699_15	6500.XP_005092325.1	3.726e-93	319.0	COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria	33208|Metazoa	ET	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
HSJS3_k127_4166699_3	1120971.AUCA01000065_gene1882	6.133e-174	590.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,277XR@186823|Alicyclobacillaceae	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HSJS3_k127_4166699_23	379066.GAU_1355	2.41e-40	169.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
HSJS3_k127_4166699_9	378806.STAUR_4654	1.968e-113	387.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HSJS3_k127_4166699_37	861299.J421_0091	0.0003772	48.0	28XFN@1|root,2ZJD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4166699_28	309807.SRU_0806	1.598e-23	113.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
HSJS3_k127_4166699_5	443152.MDG893_04739	8.581e-150	496.0	COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,1RYR4@1236|Gammaproteobacteria,465J4@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1226 Kef-type K transport systems	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
HSJS3_k127_4166699_7	1379270.AUXF01000003_gene3657	3.715e-143	459.0	COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HSJS3_k127_4168879_3	985255.APHJ01000026_gene2359	3.409e-93	313.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2P6GI@244698|Gillisia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HSJS3_k127_4168879_11	517418.Ctha_2705	5.658e-06	58.0	29GHY@1|root,303FP@2|Bacteria,1FFD5@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4168879_9	1303518.CCALI_01175	5.478e-15	85.0	COG0607@1|root,32YCZ@2|Bacteria	2|Bacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HSJS3_k127_4168879_5	1123256.KB907925_gene1355	1.639e-69	251.0	COG0740@1|root,COG0740@2|Bacteria,1RBNX@1224|Proteobacteria,1S4TV@1236|Gammaproteobacteria,1X6ND@135614|Xanthomonadales	135614|Xanthomonadales	OU	Clp protease	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
HSJS3_k127_4168879_4	309807.SRU_2346	2.042e-89	311.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
HSJS3_k127_4168879_10	1132509.C447_07903	1.673e-11	73.0	COG3794@1|root,arCOG02921@2157|Archaea,2XX78@28890|Euryarchaeota,241G7@183963|Halobacteria	28890|Euryarchaeota	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
HSJS3_k127_4168879_7	886293.Sinac_2076	3.361e-35	145.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HSJS3_k127_4168879_1	861299.J421_2356	1.439e-231	747.0	COG0480@1|root,COG0480@2|Bacteria,1ZTFA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
HSJS3_k127_4168879_6	1128421.JAGA01000003_gene2924	8.566e-62	222.0	2CAZH@1|root,2Z7RU@2|Bacteria,2NRIS@2323|unclassified Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
HSJS3_k127_4168879_0	1128421.JAGA01000003_gene2923	0.0	1004.0	COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria	2|Bacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HSJS3_k127_4168879_2	1128421.JAGA01000003_gene2922	4.639e-114	372.0	COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
HSJS3_k127_4168879_8	180281.CPCC7001_125	7.266e-33	132.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,22RTY@167375|Cyanobium	1117|Cyanobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HSJS3_k127_4181975_10	1267535.KB906767_gene4512	2.34e-85	302.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_4181975_11	443144.GM21_1947	2.545e-76	271.0	COG0280@1|root,COG0280@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
HSJS3_k127_4181975_14	75379.Tint_0744	2.696e-49	186.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,1KKNP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HSJS3_k127_4181975_18	861299.J421_3458	7.132e-37	159.0	COG0742@1|root,COG0742@2|Bacteria,1ZTVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HSJS3_k127_4181975_1	861299.J421_3460	5.887e-136	454.0	COG0608@1|root,COG0608@2|Bacteria,1ZTGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HSJS3_k127_4181975_23	1279009.ADICEAN_01911	1.278e-14	83.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,47JBK@768503|Cytophagia	976|Bacteroidetes	S	Zn-ribbon protein, possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
HSJS3_k127_4181975_5	379066.GAU_1891	1.385e-125	425.0	COG0358@1|root,COG0358@2|Bacteria,1ZSTR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
HSJS3_k127_4181975_2	292459.STH1115	7.825e-131	452.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HSJS3_k127_4181975_20	1200557.JHWV01000006_gene1896	6.386e-31	126.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4H4MK@909932|Negativicutes	909932|Negativicutes	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HSJS3_k127_4181975_17	1122169.AREN01000015_gene1093	7.262e-42	158.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1JEIC@118969|Legionellales	118969|Legionellales	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HSJS3_k127_4181975_16	309801.trd_0343	2.15e-42	168.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,27Y0Q@189775|Thermomicrobia	189775|Thermomicrobia	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HSJS3_k127_4181975_6	1379698.RBG1_1C00001G1488	6.541e-113	377.0	COG0484@1|root,COG0484@2|Bacteria,2NNNG@2323|unclassified Bacteria	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HSJS3_k127_4181975_8	379066.GAU_1899	9.485e-105	352.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
HSJS3_k127_4181975_9	861299.J421_3470	9.407e-94	325.0	COG0635@1|root,COG0635@2|Bacteria,1ZSSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HSJS3_k127_4181975_12	279714.FuraDRAFT_2797	1.609e-67	244.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,2KPZT@206351|Neisseriales	206351|Neisseriales	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HSJS3_k127_4181975_4	861299.J421_3472	1.561e-126	414.0	COG0536@1|root,COG0536@2|Bacteria,1ZSVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
HSJS3_k127_4181975_7	861299.J421_2940	2.874e-108	370.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
HSJS3_k127_4181975_15	1121428.DESHY_40111___1	1.313e-47	179.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,2624N@186807|Peptococcaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
HSJS3_k127_4181975_0	861299.J421_3601	3.652e-211	665.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
HSJS3_k127_4181975_22	861299.J421_2938	1.024e-16	92.0	COG3679@1|root,COG3679@2|Bacteria,1ZTRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HSJS3_k127_4181975_13	338966.Ppro_3005	1.915e-64	235.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,43TP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
HSJS3_k127_4181975_3	861299.J421_2936	1.319e-128	420.0	COG0216@1|root,COG0216@2|Bacteria,1ZSNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HSJS3_k127_4181975_21	411471.SUBVAR_05136	2.179e-22	102.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HSJS3_k127_4181975_19	644282.Deba_1054	2.498e-34	151.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
HSJS3_k127_4181975_24	1379270.AUXF01000005_gene488	7.044e-08	56.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HSJS3_k127_421515_6	1379270.AUXF01000005_gene723	3.162e-74	263.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HSJS3_k127_421515_8	195250.CM001776_gene2878	5.352e-44	175.0	COG0307@1|root,COG0307@2|Bacteria,1G1C6@1117|Cyanobacteria,1GZ30@1129|Synechococcus	1117|Cyanobacteria	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HSJS3_k127_421515_0	1158345.JNLL01000001_gene1100	1.527e-166	532.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2G3UE@200783|Aquificae	200783|Aquificae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HSJS3_k127_421515_7	1415778.JQMM01000001_gene801	7.989e-45	169.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1J5Y6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0380	DMRL_synthase
HSJS3_k127_421515_14	429009.Adeg_1279	6.326e-19	100.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,42H28@68295|Thermoanaerobacterales	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HSJS3_k127_421515_4	861299.J421_3119	1.037e-114	383.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_421515_3	861299.J421_3121	1.997e-117	385.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HSJS3_k127_421515_16	309798.COPRO5265_1498	1.497e-05	53.0	COG2893@1|root,COG2893@2|Bacteria,1VG0G@1239|Firmicutes,24SWY@186801|Clostridia,42H4D@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
HSJS3_k127_421515_11	1379270.AUXF01000005_gene732	6.206e-29	123.0	COG3444@1|root,COG3444@2|Bacteria,1ZTQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose subfamily IIB component	-	-	-	ko:K19507	ko02060,map02060	M00764	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.19	-	-	PTSIIB_sorb
HSJS3_k127_421515_17	1545702.LACWKB8_0348	2.085e-05	55.0	COG3715@1|root,COG3715@2|Bacteria,1UZ1T@1239|Firmicutes,4HF54@91061|Bacilli,3FC9H@33958|Lactobacillaceae	91061|Bacilli	G	PTS system sorbose-specific iic component	ptsC	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
HSJS3_k127_421515_10	861299.J421_3125	1.387e-38	154.0	COG3716@1|root,COG3716@2|Bacteria,1ZTJH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
HSJS3_k127_421515_12	1379270.AUXF01000005_gene735	2.225e-23	106.0	COG1925@1|root,COG1925@2|Bacteria,1ZTYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HSJS3_k127_421515_2	1408254.T458_27735	2.839e-123	417.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,26QD5@186822|Paenibacillaceae	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HSJS3_k127_421515_1	861299.J421_3128	1.277e-165	529.0	COG0192@1|root,COG0192@2|Bacteria,1ZSZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HSJS3_k127_421515_9	1379270.AUXF01000005_gene738	2.234e-39	155.0	COG1259@1|root,COG1259@2|Bacteria,1ZTKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
HSJS3_k127_421515_13	1379270.AUXF01000005_gene739	3.242e-19	102.0	COG2010@1|root,COG2010@2|Bacteria,1ZT9T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_421515_15	1292373.H640_02837	5.462e-14	83.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4DP6A@85009|Propionibacteriales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HSJS3_k127_421515_5	398767.Glov_3567	4.892e-110	368.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
HSJS3_k127_4259713_0	1123367.C666_01495	0.0	1067.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2VKIR@28216|Betaproteobacteria,2KVIK@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
HSJS3_k127_4259713_10	1304880.JAGB01000004_gene1371	7.345e-83	290.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia	186801|Clostridia	L	Ser Thr phosphatase family protein	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
HSJS3_k127_4259713_8	1304880.JAGB01000004_gene1370	3.269e-96	347.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
HSJS3_k127_4259713_14	261292.Nit79A3_1337	9.047e-43	168.0	COG2267@1|root,COG2267@2|Bacteria,1PE8E@1224|Proteobacteria,2W9K3@28216|Betaproteobacteria,373RZ@32003|Nitrosomonadales	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS3_k127_4259713_2	748449.Halha_0730	2.074e-187	620.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WB3A@53433|Halanaerobiales	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HSJS3_k127_4259713_19	479432.Sros_6751	4.618e-06	59.0	COG1503@1|root,COG1503@2|Bacteria,2IJI5@201174|Actinobacteria,4EMMU@85012|Streptosporangiales	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4259713_4	1121104.AQXH01000001_gene1476	5.176e-164	531.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1IUY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HSJS3_k127_4259713_13	880071.Fleli_1580	1.052e-46	179.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes,47RXQ@768503|Cytophagia	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
HSJS3_k127_4259713_12	404589.Anae109_4241	1.594e-71	250.0	COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,43AKT@68525|delta/epsilon subdivisions,2X60V@28221|Deltaproteobacteria,2Z23B@29|Myxococcales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
HSJS3_k127_4259713_5	404589.Anae109_4240	2.955e-152	492.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,437TD@68525|delta/epsilon subdivisions,2WT6I@28221|Deltaproteobacteria,2YX1E@29|Myxococcales	28221|Deltaproteobacteria	C	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
HSJS3_k127_4259713_7	404589.Anae109_4239	3.787e-114	382.0	COG0654@1|root,COG0654@2|Bacteria,1R03K@1224|Proteobacteria,43CQQ@68525|delta/epsilon subdivisions,2X7Y6@28221|Deltaproteobacteria,2Z1K0@29|Myxococcales	28221|Deltaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HSJS3_k127_4259713_18	1121085.AUCI01000002_gene4020	2.322e-08	58.0	2BFS6@1|root,329M0@2|Bacteria,1UBZZ@1239|Firmicutes,4INFW@91061|Bacilli,1ZNF2@1386|Bacillus	91061|Bacilli	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
HSJS3_k127_4259713_20	1232410.KI421412_gene336	0.0002115	50.0	29SGJ@1|root,2ZKKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4259713_17	479433.Caci_1944	3.117e-11	66.0	2DG6U@1|root,2ZURF@2|Bacteria,2HCGM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4259713_15	379066.GAU_1552	6.864e-35	144.0	COG1496@1|root,COG1496@2|Bacteria,1ZTTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HSJS3_k127_4259713_1	1122939.ATUD01000001_gene152	3.651e-279	889.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CPG1@84995|Rubrobacteria	84995|Rubrobacteria	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,Biotin_lipoyl,E1_dh,E3_binding,OxoGdeHyase_C,Transket_pyr
HSJS3_k127_4259713_9	502025.Hoch_5173	1.21e-94	320.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2YUHA@29|Myxococcales	28221|Deltaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_4259713_11	886293.Sinac_2516	1.642e-73	256.0	COG0847@1|root,COG0847@2|Bacteria,2IZQY@203682|Planctomycetes	203682|Planctomycetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HSJS3_k127_4259713_16	215803.DB30_2479	2.269e-20	98.0	2C5K3@1|root,344B2@2|Bacteria,1QMRP@1224|Proteobacteria,43E9X@68525|delta/epsilon subdivisions,2X8WK@28221|Deltaproteobacteria,2Z0QP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4259713_6	105559.Nwat_1689	6.812e-133	437.0	COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1WYC3@135613|Chromatiales	135613|Chromatiales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HSJS3_k127_4259713_3	219305.MCAG_01505	1.572e-164	529.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria,4DB5R@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
HSJS3_k127_4278149_2	643648.Slip_0135	5.984e-20	95.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,42JVZ@68298|Syntrophomonadaceae	186801|Clostridia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HSJS3_k127_4278149_0	1382356.JQMP01000001_gene1202	4.483e-91	312.0	COG0413@1|root,COG0413@2|Bacteria,2G5TQ@200795|Chloroflexi,27XR8@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HSJS3_k127_4278149_1	357808.RoseRS_0744	2.298e-69	243.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HSJS3_k127_4295070_2	633149.Bresu_0327	3.158e-114	379.0	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,2U85Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_4295070_5	1121946.AUAX01000055_gene3677	1.171e-14	86.0	COG1075@1|root,COG1075@2|Bacteria,2I090@201174|Actinobacteria,4DG74@85008|Micromonosporales	201174|Actinobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
HSJS3_k127_4295070_1	324602.Caur_0607	1.407e-130	445.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
HSJS3_k127_4295070_4	216594.MMAR_2405	3.168e-36	157.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
HSJS3_k127_4295070_3	1121104.AQXH01000004_gene155	1.009e-66	239.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
HSJS3_k127_4295070_0	861299.J421_2004	9.428e-207	672.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZTB3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HSJS3_k127_4338020_16	1144275.COCOR_00518	6.77e-09	62.0	COG1612@1|root,COG1612@2|Bacteria,1PV6F@1224|Proteobacteria,4303Y@68525|delta/epsilon subdivisions,2WVAK@28221|Deltaproteobacteria,2YUJ2@29|Myxococcales	28221|Deltaproteobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
HSJS3_k127_4338020_0	384765.SIAM614_22982	5.258e-233	731.0	COG0069@1|root,COG4638@1|root,COG0069@2|Bacteria,COG4638@2|Bacteria,1MU7B@1224|Proteobacteria,2TRWC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rieske,zf-CDGSH
HSJS3_k127_4338020_6	1379270.AUXF01000004_gene3256	1.935e-114	380.0	COG0809@1|root,COG0809@2|Bacteria,1ZSV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HSJS3_k127_4338020_3	861299.J421_2575	3.719e-151	489.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HSJS3_k127_4338020_17	240015.ACP_0350	8.044e-06	52.0	COG1918@1|root,COG1918@2|Bacteria,3Y92B@57723|Acidobacteria,2JNUD@204432|Acidobacteriia	204432|Acidobacteriia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HSJS3_k127_4338020_2	1267535.KB906767_gene1113	2.999e-213	679.0	COG0370@1|root,COG0370@2|Bacteria,3Y3CZ@57723|Acidobacteria,2JJQ0@204432|Acidobacteriia	204432|Acidobacteriia	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
HSJS3_k127_4338020_14	1379270.AUXF01000004_gene3249	1.398e-35	153.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HSJS3_k127_4338020_13	379066.GAU_0634	1.124e-44	175.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HSJS3_k127_4338020_8	861299.J421_2581	9.951e-93	311.0	COG0217@1|root,COG0217@2|Bacteria,1ZTF4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HSJS3_k127_4338020_5	1541065.JRFE01000032_gene3585	2.626e-131	438.0	COG0154@1|root,COG2931@1|root,COG0154@2|Bacteria,COG2931@2|Bacteria,1G1H1@1117|Cyanobacteria,3VJEW@52604|Pleurocapsales	1117|Cyanobacteria	JQ	Amidase	-	-	-	ko:K21801	ko00380,ko01100,map00380,map01100	-	-	-	ko00000,ko00001,ko01000	-	-	-	Amidase
HSJS3_k127_4338020_4	861299.J421_0659	6.09e-146	481.0	COG0154@1|root,COG0154@2|Bacteria,1ZT2R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HSJS3_k127_4338020_7	344747.PM8797T_03239	7.183e-104	363.0	COG3424@1|root,COG3424@2|Bacteria,2IYDA@203682|Planctomycetes	203682|Planctomycetes	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
HSJS3_k127_4338020_9	180281.CPCC7001_2431	6.471e-67	248.0	COG0644@1|root,COG0644@2|Bacteria,1GKHV@1117|Cyanobacteria,22TBB@167375|Cyanobium	1117|Cyanobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
HSJS3_k127_4338020_12	180281.CPCC7001_1226	2.532e-55	202.0	COG2227@1|root,COG2227@2|Bacteria,1GQY3@1117|Cyanobacteria,22TNZ@167375|Cyanobium	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS3_k127_4338020_1	379066.GAU_3084	2.177e-227	715.0	COG1473@1|root,COG1473@2|Bacteria,1ZSTC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer
HSJS3_k127_4338020_11	861299.J421_0342	4.16e-59	234.0	COG0642@1|root,COG2205@2|Bacteria,1ZUZJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HSJS3_k127_4338020_10	861299.J421_0341	8.538e-67	240.0	COG0745@1|root,COG0745@2|Bacteria,1ZUFQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HSJS3_k127_4338020_15	1408473.JHXO01000017_gene2951	4.349e-18	97.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,2FXQC@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
HSJS3_k127_4352384_2	1123024.AUII01000019_gene3990	0.0006963	48.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4E8X8@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156
HSJS3_k127_4352384_1	1380390.JIAT01000010_gene4637	3.136e-32	138.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4CRKU@84995|Rubrobacteria	84995|Rubrobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
HSJS3_k127_4352384_0	1079460.ATTQ01000016_gene5421	3.481e-115	397.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
HSJS3_k127_4353456_0	331869.BAL199_16353	2.764e-168	546.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,4BPZA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HSJS3_k127_4353456_1	266779.Meso_0348	1.321e-61	222.0	2E3HM@1|root,32YG7@2|Bacteria,1NM0U@1224|Proteobacteria,2TZYE@28211|Alphaproteobacteria,43RX1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4375057_0	1379270.AUXF01000005_gene693	2.47e-118	393.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
HSJS3_k127_4375057_3	861299.J421_3078	9.263e-19	99.0	COG1589@1|root,COG1589@2|Bacteria,1ZTRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
HSJS3_k127_4375057_1	1184607.AUCHE_01_00390	4.671e-104	369.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4F6C3@85018|Dermatophilaceae	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_4375057_2	518766.Rmar_2701	2.118e-77	273.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1FIU4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HSJS3_k127_4390119_8	1125863.JAFN01000001_gene2764	1.744e-136	449.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
HSJS3_k127_4390119_42	319225.Plut_2036	6.123e-08	56.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	fmdB	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
HSJS3_k127_4390119_47	1499968.TCA2_5335	4.901e-05	49.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HRQH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4390119_43	1461580.CCAS010000118_gene4580	5.219e-07	53.0	2DDW9@1|root,2ZJJ8@2|Bacteria,1W4EI@1239|Firmicutes,4I1RT@91061|Bacilli,1ZK7C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4390119_16	1403819.BATR01000092_gene2754	1.127e-90	316.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
HSJS3_k127_4390119_30	1177181.T9A_00687	7.621e-40	152.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,1XKHH@135619|Oceanospirillales	135619|Oceanospirillales	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
HSJS3_k127_4390119_7	243231.GSU0752	1.447e-136	448.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,43TZS@69541|Desulfuromonadales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
HSJS3_k127_4390119_27	1282360.ABAC460_10930	2.169e-45	177.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2U3WV@28211|Alphaproteobacteria,2KK3E@204458|Caulobacterales	204458|Caulobacterales	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
HSJS3_k127_4390119_2	1123253.AUBD01000010_gene2193	6.181e-240	775.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales	135614|Xanthomonadales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
HSJS3_k127_4390119_34	1056820.KB900699_gene1277	3.11e-27	118.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria,2PP92@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HSJS3_k127_4390119_4	886293.Sinac_6978	1.695e-190	613.0	COG0488@1|root,COG0488@2|Bacteria,2IX59@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HSJS3_k127_4390119_17	405948.SACE_1566	5.191e-86	305.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4DZQJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_NADP
HSJS3_k127_4390119_35	861299.J421_2526	3.823e-27	123.0	COG2802@1|root,COG2802@2|Bacteria,1ZUZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
HSJS3_k127_4390119_15	1121930.AQXG01000019_gene82	3.614e-95	319.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes	976|Bacteroidetes	F	Creatinine amidohydrolase	crnA	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HSJS3_k127_4390119_21	517418.Ctha_1804	7.283e-67	237.0	COG2859@1|root,COG2859@2|Bacteria,1FEXS@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
HSJS3_k127_4390119_22	322710.Avin_11210	1.265e-64	239.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria	1224|Proteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CIA30
HSJS3_k127_4390119_14	861299.J421_3108	8.376e-98	330.0	2F044@1|root,33T7T@2|Bacteria,1ZTDC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4390119_1	1117647.M5M_18295	1.143e-256	808.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,1J4VU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0339 Zn-dependent oligopeptidases	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
HSJS3_k127_4390119_37	426355.Mrad2831_0496	1.291e-20	104.0	COG0840@1|root,COG1017@1|root,COG0840@2|Bacteria,COG1017@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,1JXPW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CNT	Globin	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Globin,HAMP,MCPsignal
HSJS3_k127_4390119_40	656024.FsymDg_1261	8.004e-09	67.0	COG1357@1|root,COG1357@2|Bacteria,2IB55@201174|Actinobacteria	201174|Actinobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
HSJS3_k127_4390119_29	234267.Acid_1844	1.986e-43	164.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS3_k127_4390119_12	1379270.AUXF01000001_gene2428	4.633e-99	340.0	COG2514@1|root,COG2514@2|Bacteria,1ZTDT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HSJS3_k127_4390119_32	861299.J421_0824	6.799e-33	139.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	catD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HSJS3_k127_4390119_31	861299.J421_0770	4.034e-35	150.0	COG1846@1|root,COG1846@2|Bacteria,1ZU5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HSJS3_k127_4390119_39	1266914.ATUK01000014_gene2257	2.203e-12	81.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales	135613|Chromatiales	M	PFAM AsmA family protein	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
HSJS3_k127_4390119_19	1123503.KB908057_gene2511	8.533e-70	248.0	COG3591@1|root,COG3591@2|Bacteria,1NQI1@1224|Proteobacteria,2U5SD@28211|Alphaproteobacteria,2KIHQ@204458|Caulobacterales	204458|Caulobacterales	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4390119_24	926550.CLDAP_05980	1.053e-55	214.0	COG3842@1|root,COG3842@2|Bacteria,2G6S3@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE_2
HSJS3_k127_4390119_20	379066.GAU_2885	4.865e-67	246.0	COG4149@1|root,COG4149@2|Bacteria	2|Bacteria	P	molybdate abc transporter	modB	-	-	ko:K02018,ko:K15496	ko02010,map02010	M00189,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5,3.A.1.8	-	-	BPD_transp_1
HSJS3_k127_4390119_25	292459.STH996	5.595e-48	186.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia	186801|Clostridia	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
HSJS3_k127_4390119_18	479434.Sthe_3086	6.617e-72	257.0	COG1476@1|root,COG1910@1|root,COG1476@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi,27Y40@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcriptional Regulator of molybdate metabolism, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,PBP_like
HSJS3_k127_4390119_26	521674.Plim_3696	6.276e-46	178.0	COG0288@1|root,COG0288@2|Bacteria,2J02F@203682|Planctomycetes	203682|Planctomycetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HSJS3_k127_4390119_9	1379270.AUXF01000003_gene3364	1.304e-134	436.0	COG3329@1|root,COG3329@2|Bacteria	2|Bacteria	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
HSJS3_k127_4390119_36	300852.55771898	7.349e-26	109.0	COG0347@1|root,COG0347@2|Bacteria,1WK66@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4390119_23	502025.Hoch_2991	8.182e-64	239.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HSJS3_k127_4390119_46	1297742.A176_04929	3.737e-05	50.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_4390119_41	861299.J421_0393	5.311e-08	56.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0393|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4390119_3	1121930.AQXG01000001_gene1298	3.015e-195	637.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
HSJS3_k127_4390119_6	1254432.SCE1572_50310	2.488e-166	550.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,438BA@68525|delta/epsilon subdivisions,2X3KK@28221|Deltaproteobacteria,2YWFN@29|Myxococcales	28221|Deltaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_4390119_10	309807.SRU_2448	3.265e-109	373.0	COG1228@1|root,COG1228@2|Bacteria,4P0JM@976|Bacteroidetes	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_4390119_5	574966.KB898651_gene2097	2.34e-176	570.0	COG1823@1|root,COG1823@2|Bacteria,1R3F8@1224|Proteobacteria,1T677@1236|Gammaproteobacteria,1XS30@135619|Oceanospirillales	135619|Oceanospirillales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K06956	-	-	-	-	ko00000	-	-	-	SDF
HSJS3_k127_4390119_13	983917.RGE_30580	1.016e-98	336.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2WEME@28216|Betaproteobacteria,1KN2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
HSJS3_k127_4390119_33	1280941.HY2_01015	6.728e-28	123.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,2TSDQ@28211|Alphaproteobacteria,43YQB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
HSJS3_k127_4390119_38	861299.J421_1004	2.355e-16	87.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
HSJS3_k127_4390119_28	391625.PPSIR1_23129	6.156e-44	174.0	2AF1T@1|root,31507@2|Bacteria,1PUYN@1224|Proteobacteria,43842@68525|delta/epsilon subdivisions,2X3E0@28221|Deltaproteobacteria,2YVMX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4390119_0	309807.SRU_2720	2.22e-273	872.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HSJS3_k127_4390119_11	483219.LILAB_05640	7.125e-106	355.0	COG1192@1|root,COG1192@2|Bacteria,1Q4ZN@1224|Proteobacteria,43082@68525|delta/epsilon subdivisions,2WV4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HSJS3_k127_4390119_45	1242864.D187_002139	5.128e-06	59.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
HSJS3_k127_4390119_48	111781.Lepto7376_0229	8.055e-05	46.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
HSJS3_k127_4476983_9	1128421.JAGA01000001_gene2365	1.806e-13	74.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
HSJS3_k127_4476983_12	1415779.JOMH01000001_gene1725	4.537e-06	50.0	28JE9@1|root,2Z98H@2|Bacteria,1R6X4@1224|Proteobacteria,1S09Q@1236|Gammaproteobacteria,1X9MP@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4476983_3	331869.BAL199_20420	2.666e-153	498.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,4BPTY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD linked oxidases, C-terminal domain	MA20_27310	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
HSJS3_k127_4476983_1	550540.Fbal_0688	9.986e-177	561.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYL1228.KPN_03348	2-Hacid_dh,2-Hacid_dh_C,ACT
HSJS3_k127_4476983_5	1337936.IJ00_04735	6.443e-58	215.0	COG4912@1|root,COG4912@2|Bacteria,1G8NP@1117|Cyanobacteria	1117|Cyanobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HSJS3_k127_4476983_4	765420.OSCT_0403	7.217e-126	419.0	COG0530@1|root,COG0530@2|Bacteria,2G6GV@200795|Chloroflexi,376V8@32061|Chloroflexia	32061|Chloroflexia	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HSJS3_k127_4476983_2	344747.PM8797T_18104	2.276e-169	550.0	COG1115@1|root,COG1115@2|Bacteria,2IX3I@203682|Planctomycetes	203682|Planctomycetes	U	COG1115 Na alanine symporter	dagA	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HSJS3_k127_4476983_10	680198.SCAB_90731	3.843e-12	70.0	COG1695@1|root,COG1695@2|Bacteria,2IQ70@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator padr family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_4476983_0	1183438.GKIL_4354	1.389e-183	606.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_4476983_6	1192034.CAP_1726	1.64e-54	202.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria,43CA0@68525|delta/epsilon subdivisions,2X7KG@28221|Deltaproteobacteria,2YVW6@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS3_k127_4476983_11	856793.MICA_1695	2.068e-09	59.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4BP62@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	cckA	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
HSJS3_k127_4476983_8	1121017.AUFG01000024_gene2059	8.836e-16	79.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4FF43@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HSJS3_k127_4479656_2	517418.Ctha_1737	5.714e-156	526.0	COG1629@1|root,COG4771@2|Bacteria,1FEFM@1090|Chlorobi	1090|Chlorobi	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HSJS3_k127_4479656_7	379066.GAU_2485	4.777e-102	342.0	COG1208@1|root,COG1208@2|Bacteria,1ZSYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HSJS3_k127_4479656_24	935565.JAEM01000045_gene651	6.134e-31	134.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,2PWHI@265|Paracoccus	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
HSJS3_k127_4479656_32	215803.DB30_2683	2.551e-07	59.0	COG4446@1|root,COG4446@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
HSJS3_k127_4479656_29	235909.GK0639	9.51e-14	84.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1WEDY@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
HSJS3_k127_4479656_3	1379270.AUXF01000004_gene3069	1.707e-147	491.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
HSJS3_k127_4479656_10	379066.GAU_0826	9.121e-91	308.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_4479656_19	706587.Desti_4625	3.18e-51	201.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HSJS3_k127_4479656_31	272557.APE_1648.1	7.102e-08	63.0	COG2110@1|root,arCOG04225@2157|Archaea,2XQEQ@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
HSJS3_k127_4479656_28	663610.JQKO01000010_gene2275	1.068e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3NA3Z@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
HSJS3_k127_4479656_25	290397.Adeh_1133	5.161e-29	120.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
HSJS3_k127_4479656_4	1382359.JIAL01000001_gene2768	4.558e-140	471.0	COG1022@1|root,COG1022@2|Bacteria,3Y2KU@57723|Acidobacteria,2JHTA@204432|Acidobacteriia	204432|Acidobacteriia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
HSJS3_k127_4479656_27	997296.PB1_11184	2.589e-21	99.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HIEM@91061|Bacilli,1ZQR8@1386|Bacillus	91061|Bacilli	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
HSJS3_k127_4479656_26	1379270.AUXF01000004_gene3091	6.281e-22	102.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
HSJS3_k127_4479656_30	861299.J421_2706	1.392e-10	72.0	2FCPE@1|root,344SN@2|Bacteria,1ZU2F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4479656_18	379066.GAU_0781	1.33e-52	199.0	COG4221@1|root,COG4221@2|Bacteria,1ZTPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS3_k127_4479656_12	1379270.AUXF01000004_gene3097	8.822e-76	264.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HSJS3_k127_4479656_20	391596.PBAL39_24440	8.265e-44	167.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1IXEM@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HSJS3_k127_4479656_9	861299.J421_3762	2.306e-92	311.0	COG0648@1|root,COG0648@2|Bacteria,1ZSY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
HSJS3_k127_4479656_1	1896.JOAU01000016_gene2912	5.523e-162	522.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
HSJS3_k127_4479656_13	649638.Trad_2700	1.274e-64	229.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS3_k127_4479656_16	1192034.CAP_3784	9.598e-54	204.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,434F1@68525|delta/epsilon subdivisions,2WYSG@28221|Deltaproteobacteria,2Z0HG@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
HSJS3_k127_4479656_5	861299.J421_3590	6.85e-130	422.0	COG0492@1|root,COG0492@2|Bacteria,1ZTEH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HSJS3_k127_4479656_6	1111479.AXAR01000003_gene1676	7.832e-111	368.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,279CW@186823|Alicyclobacillaceae	91061|Bacilli	C	Ferredoxin--NADP reductase	trxB5	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
HSJS3_k127_4479656_15	523841.HFX_2543	4.847e-54	201.0	arCOG07538@1|root,arCOG07538@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4479656_23	439235.Dalk_4322	1.785e-31	141.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2MJDG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
HSJS3_k127_4479656_8	1125863.JAFN01000001_gene2253	4.311e-101	346.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
HSJS3_k127_4479656_17	1101189.AQUO01000001_gene1139	1.097e-53	205.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,2PUP2@265|Paracoccus	28211|Alphaproteobacteria	S	AI-2E family transporter	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
HSJS3_k127_4479656_22	1379270.AUXF01000007_gene1059	5.908e-40	162.0	COG1463@1|root,COG1463@2|Bacteria,1ZUJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HSJS3_k127_4479656_11	861299.J421_2625	4.505e-90	316.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HSJS3_k127_4479656_21	1122613.ATUP01000002_gene2508	1.103e-41	163.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,43WM1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HSJS3_k127_4479656_14	880072.Desac_0962	2.46e-56	211.0	COG1994@1|root,COG1994@2|Bacteria,1QZHR@1224|Proteobacteria,43CIT@68525|delta/epsilon subdivisions,2X7T2@28221|Deltaproteobacteria,2MRQV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HSJS3_k127_4479656_0	1125863.JAFN01000001_gene3383	6.805e-168	540.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HSJS3_k127_4479656_33	1379270.AUXF01000004_gene3215	1.441e-05	56.0	COG0816@1|root,COG0816@2|Bacteria,1ZTWG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HSJS3_k127_4500055_16	388467.A19Y_2033	8.028e-06	59.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
HSJS3_k127_4500055_12	326427.Cagg_2882	1.274e-19	95.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
HSJS3_k127_4500055_4	861299.J421_4487	9.572e-77	270.0	COG3595@1|root,COG3595@2|Bacteria,1ZTJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HSJS3_k127_4500055_17	234267.Acid_3083	4.049e-05	56.0	COG3595@1|root,COG3595@2|Bacteria,3Y5AF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4500055_15	1535422.ND16A_3501	3.424e-08	64.0	COG3595@1|root,COG3595@2|Bacteria,1NG89@1224|Proteobacteria,1SCZV@1236|Gammaproteobacteria,2Q846@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HSJS3_k127_4500055_13	1379270.AUXF01000001_gene2633	1.721e-13	83.0	2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4500055_8	861299.J421_4375	2.958e-46	177.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_4500055_10	313612.L8106_29480	2.5e-40	159.0	COG0584@1|root,COG0584@2|Bacteria,1G20Z@1117|Cyanobacteria,1H9KY@1150|Oscillatoriales	1117|Cyanobacteria	C	Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
HSJS3_k127_4500055_1	1121430.JMLG01000002_gene1106	1.899e-139	467.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248QX@186801|Clostridia,260AJ@186807|Peptococcaceae	186801|Clostridia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HSJS3_k127_4500055_6	292459.STH749	1.375e-52	208.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
HSJS3_k127_4500055_14	1340493.JNIF01000003_gene1555	1.265e-10	70.0	COG2133@1|root,COG3258@1|root,COG2133@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	gdhB	-	1.1.5.2,1.1.9.1,1.8.2.2	ko:K00117,ko:K02030,ko:K17760,ko:K19713	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	M00236	R06620	RC00066	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	Cytochrom_C,Cytochrome_CBB3,GSDH,PA14,PQQ,PSCyt3,PSD3,PSD4,PSD5,SBP_bac_3
HSJS3_k127_4500055_11	1123511.KB905846_gene2614	7.118e-27	124.0	COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1VA6T@1239|Firmicutes,4H4ZE@909932|Negativicutes	909932|Negativicutes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
HSJS3_k127_4500055_3	1306406.ASHX01000002_gene4932	1.853e-84	290.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HSJS3_k127_4500055_2	596151.DesfrDRAFT_3374	7.717e-97	329.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QAG@68525|delta/epsilon subdivisions,2X5DT@28221|Deltaproteobacteria,2MGPX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
HSJS3_k127_4500055_5	1121033.AUCF01000024_gene250	2.781e-76	263.0	COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,2U5PF@28211|Alphaproteobacteria,2JSDP@204441|Rhodospirillales	204441|Rhodospirillales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HSJS3_k127_4500055_9	1569209.BBPH01000076_gene302	9.81e-43	167.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2UBYU@28211|Alphaproteobacteria,2PUT2@265|Paracoccus	28211|Alphaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB,YceI
HSJS3_k127_4500055_7	330214.NIDE0596	1.37e-48	186.0	COG0253@1|root,COG0253@2|Bacteria,3J0JV@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HSJS3_k127_4500055_0	880073.Calab_1134	2.485e-182	597.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_4549175_1	1382306.JNIM01000001_gene2874	5.621e-53	199.0	COG0559@1|root,COG0559@2|Bacteria,2G6M5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HSJS3_k127_4549175_0	1125863.JAFN01000001_gene400	4.704e-155	503.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
HSJS3_k127_4556139_15	1278307.KB907040_gene1962	1.011e-15	79.0	COG1550@1|root,COG1550@2|Bacteria,1NGDU@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
HSJS3_k127_4556139_14	1122918.KB907258_gene2556	2.327e-25	111.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,26YF0@186822|Paenibacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HSJS3_k127_4556139_10	502025.Hoch_3849	4.067e-62	225.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
HSJS3_k127_4556139_9	861299.J421_3191	1.579e-80	283.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HSJS3_k127_4556139_13	246195.DNO_1048	7.318e-29	118.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HSJS3_k127_4556139_0	861299.J421_3401	2.298e-273	857.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HSJS3_k127_4556139_6	861299.J421_3400	1.329e-115	388.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_4556139_2	861299.J421_3399	1.675e-159	514.0	COG0686@1|root,COG0686@2|Bacteria,1ZSSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HSJS3_k127_4556139_11	452662.SJA_C1-35120	3.645e-44	171.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HSJS3_k127_4556139_1	861299.J421_3398	3.585e-166	529.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HSJS3_k127_4556139_12	379066.GAU_1760	8.83e-36	148.0	COG1792@1|root,COG1792@2|Bacteria,1ZSYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HSJS3_k127_4556139_16	861299.J421_3396	2.665e-09	65.0	2CIX2@1|root,33ZZP@2|Bacteria,1ZTZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
HSJS3_k127_4556139_3	379066.GAU_1758	8.134e-145	482.0	COG0768@1|root,COG0768@2|Bacteria,1ZSX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HSJS3_k127_4556139_5	379066.GAU_1757	2.872e-120	400.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HSJS3_k127_4556139_7	243231.GSU2370	1.268e-98	330.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WP9B@28221|Deltaproteobacteria,43U3E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HSJS3_k127_4556139_8	379066.GAU_1755	4.159e-83	295.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
HSJS3_k127_4556139_4	861299.J421_3391	1.393e-128	425.0	COG0124@1|root,COG0124@2|Bacteria,1ZSXX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
HSJS3_k127_4566979_1	861299.J421_3780	3.454e-181	576.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HSJS3_k127_4566979_0	1191523.MROS_1041	5.25e-313	982.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HSJS3_k127_4566979_2	1136417.AZWE01000007_gene1951	4.271e-76	270.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DB0R@85008|Micromonosporales	201174|Actinobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
HSJS3_k127_4566979_3	1173028.ANKO01000116_gene5724	3.834e-51	192.0	COG0546@1|root,COG0546@2|Bacteria,1G6AW@1117|Cyanobacteria,1HCZI@1150|Oscillatoriales	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HSJS3_k127_4566979_5	443152.MDG893_03255	9.434e-40	158.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,1SASV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1651 Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HSJS3_k127_4566979_8	694429.Pyrfu_0196	0.0006898	49.0	COG1530@1|root,arCOG04307@2157|Archaea,2XQ31@28889|Crenarchaeota	28889|Crenarchaeota	J	Binds to RNA in loop regions with AU-rich sequences	aubA	-	-	ko:K22469	-	-	-	-	ko00000,ko03009	-	-	-	DUF402,RNase_E_G
HSJS3_k127_4566979_6	1121090.KB894685_gene3540	1.166e-19	102.0	COG1975@1|root,COG1975@2|Bacteria,1VFRE@1239|Firmicutes,4IKUK@91061|Bacilli,1ZHNN@1386|Bacillus	91061|Bacilli	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
HSJS3_k127_4566979_4	264732.Moth_2006	2.572e-43	172.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HSJS3_k127_4566979_7	743720.Psefu_3488	1.388e-10	64.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1S9Q1@1236|Gammaproteobacteria,1YVP8@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HSJS3_k127_4609028_16	1122963.AUHB01000006_gene2393	2.52e-36	142.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,36X45@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Oxidoreductase molybdopterin binding domain	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
HSJS3_k127_4609028_12	1123053.AUDG01000026_gene187	5.453e-46	173.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,1WZFI@135613|Chromatiales	135613|Chromatiales	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
HSJS3_k127_4609028_17	443218.AS9A_4420	4.9e-34	142.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria,238T5@1762|Mycobacteriaceae	201174|Actinobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HSJS3_k127_4609028_13	344747.PM8797T_31008	3.381e-44	172.0	COG0296@1|root,COG0561@1|root,COG0296@2|Bacteria,COG0561@2|Bacteria,2IXPW@203682|Planctomycetes	203682|Planctomycetes	G	Alpha amylase, catalytic domain	-	-	3.2.1.1,3.2.1.141	ko:K01176,ko:K01236	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	M00565	R02108,R02112,R09995,R11256,R11262	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459,S6PP
HSJS3_k127_4609028_2	1283300.ATXB01000001_gene479	4.684e-249	803.0	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1XDS7@135618|Methylococcales	135618|Methylococcales	M	Sucrose phosphate synthase, sucrose phosphatase-like	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1,S6PP
HSJS3_k127_4609028_0	105559.Nwat_3123	7.718e-283	901.0	COG0438@1|root,COG0438@2|Bacteria,1QZ01@1224|Proteobacteria,1RZJA@1236|Gammaproteobacteria,1X05E@135613|Chromatiales	135613|Chromatiales	M	sucrose synthase	-	-	2.4.1.13	ko:K00695	ko00500,ko01100,map00500,map01100	-	R00806	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glycos_transf_1,Sucrose_synth
HSJS3_k127_4609028_10	1192034.CAP_3975	1.173e-106	354.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42VTH@68525|delta/epsilon subdivisions,2WS84@28221|Deltaproteobacteria,2YYDW@29|Myxococcales	28221|Deltaproteobacteria	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HSJS3_k127_4609028_18	1121468.AUBR01000014_gene2232	1.961e-31	134.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,42GDJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
HSJS3_k127_4609028_9	861299.J421_3422	7.937e-109	371.0	COG0128@1|root,COG0128@2|Bacteria	2|Bacteria	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390	EPSP_synthase
HSJS3_k127_4609028_14	582515.KR51_00020380	3.265e-42	169.0	COG0283@1|root,COG0414@1|root,COG0283@2|Bacteria,COG0414@2|Bacteria,1G1BX@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC/cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25,6.3.2.1	ko:K13799	ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110	M00052,M00119	R00158,R00512,R01665,R02473	RC00002,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,Pantoate_ligase
HSJS3_k127_4609028_3	1379270.AUXF01000006_gene109	2.838e-230	731.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HSJS3_k127_4609028_21	401526.TcarDRAFT_0889	1.058e-07	65.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H37Z@909932|Negativicutes	909932|Negativicutes	E	Ligand-binding protein	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HSJS3_k127_4609028_1	379066.GAU_1783	1.446e-255	814.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HSJS3_k127_4609028_20	1121013.P873_05025	1.468e-20	105.0	COG0265@1|root,COG0265@2|Bacteria,1PCJA@1224|Proteobacteria,1SXM8@1236|Gammaproteobacteria,1X6DM@135614|Xanthomonadales	135614|Xanthomonadales	O	PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
HSJS3_k127_4609028_5	1128421.JAGA01000003_gene3673	8.197e-162	524.0	COG4770@1|root,COG4770@2|Bacteria,2NQKT@2323|unclassified Bacteria	2|Bacteria	I	Biotin carboxylase C-terminal domain	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3285	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
HSJS3_k127_4609028_11	292459.STH2818	1.96e-54	211.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HSJS3_k127_4609028_15	379066.GAU_1780	3.864e-37	148.0	COG4770@1|root,COG4770@2|Bacteria,1ZTVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
HSJS3_k127_4609028_4	1123405.AUMM01000010_gene1224	4.779e-208	660.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,26P9A@186821|Sporolactobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HSJS3_k127_4609028_19	1379698.RBG1_1C00001G1439	9.566e-21	95.0	COG2331@1|root,COG2331@2|Bacteria,2NQ36@2323|unclassified Bacteria	2|Bacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
HSJS3_k127_4609028_6	439292.Bsel_3203	1.042e-156	512.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,26NXQ@186821|Sporolactobacillaceae	91061|Bacilli	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HSJS3_k127_4609028_7	861299.J421_3111	8.628e-114	381.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
HSJS3_k127_4609028_8	861299.J421_3112	8.122e-113	374.0	COG0150@1|root,COG0150@2|Bacteria,1ZSQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HSJS3_k127_4609028_22	379066.GAU_1470	7.846e-06	57.0	2F30H@1|root,33VVT@2|Bacteria,1ZTRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4717277_13	1382304.JNIL01000001_gene95	8.831e-25	106.0	COG2267@1|root,COG2267@2|Bacteria,1W2QR@1239|Firmicutes,4I0G2@91061|Bacilli	91061|Bacilli	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS3_k127_4717277_1	1121957.ATVL01000009_gene1068	3.488e-146	488.0	COG0477@1|root,COG0477@2|Bacteria,4PKB1@976|Bacteroidetes,47NAF@768503|Cytophagia	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS3_k127_4717277_16	1036674.A28LD_1735	2.396e-05	52.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,2QG2W@267893|Idiomarinaceae	1236|Gammaproteobacteria	U	general secretion pathway protein	gspG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
HSJS3_k127_4717277_10	1379270.AUXF01000002_gene1118	3.213e-38	162.0	2CDZB@1|root,3340J@2|Bacteria,1ZU24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4717277_5	518766.Rmar_2799	3.216e-68	250.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes	976|Bacteroidetes	S	Iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
HSJS3_k127_4717277_14	1137799.GZ78_06635	9.281e-18	91.0	COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,1XMRX@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HSJS3_k127_4717277_8	357808.RoseRS_0914	1.254e-52	197.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HSJS3_k127_4717277_6	234267.Acid_2792	1.194e-58	218.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,3Y4XJ@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9
HSJS3_k127_4717277_3	309801.trd_1816	9.653e-69	245.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,27YVM@189775|Thermomicrobia	189775|Thermomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HSJS3_k127_4717277_15	1123267.JONN01000001_gene431	1.47e-07	58.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Response_reg
HSJS3_k127_4717277_9	314345.SPV1_11551	9.693e-43	163.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria	1224|Proteobacteria	S	metal-binding protein	copG	-	-	-	-	-	-	-	-	-	-	-	DUF411
HSJS3_k127_4717277_2	1144275.COCOR_04880	2.977e-87	301.0	COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,42XHB@68525|delta/epsilon subdivisions,2WSKY@28221|Deltaproteobacteria,2YVC2@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
HSJS3_k127_4717277_12	861299.J421_1222	1.233e-32	136.0	COG1393@1|root,COG1393@2|Bacteria,1ZTUV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
HSJS3_k127_4717277_0	379066.GAU_1458	2.284e-187	608.0	COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,DUF1566,LVIVD,SLH
HSJS3_k127_4717277_7	566466.NOR53_3363	5.576e-56	207.0	COG0823@1|root,COG0823@2|Bacteria,1N9FB@1224|Proteobacteria,1SCP0@1236|Gammaproteobacteria,1J91H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HSJS3_k127_4717277_4	357808.RoseRS_0026	1.729e-68	253.0	COG1169@1|root,COG1169@2|Bacteria,2G5RQ@200795|Chloroflexi,375P4@32061|Chloroflexia	32061|Chloroflexia	HQ	TIGRFAM isochorismate synthase	-	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
HSJS3_k127_4717277_11	518766.Rmar_0582	7.547e-37	143.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,1FJ02@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
HSJS3_k127_4752098_0	861299.J421_3780	1.337e-198	638.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HSJS3_k127_4752098_2	1379270.AUXF01000002_gene1409	2.348e-102	343.0	COG0040@1|root,COG0040@2|Bacteria,1ZSZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
HSJS3_k127_4752098_1	1242864.D187_009926	1.593e-120	415.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,2YTXD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HSJS3_k127_4752098_4	1379270.AUXF01000002_gene1407	1.605e-72	259.0	COG0079@1|root,COG0079@2|Bacteria,1ZV8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	-
HSJS3_k127_4752098_5	861299.J421_1271	1.711e-63	231.0	COG0118@1|root,COG0118@2|Bacteria,1ZTIJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HSJS3_k127_4752098_6	1379270.AUXF01000002_gene1405	3.214e-63	228.0	COG0106@1|root,COG0106@2|Bacteria,1ZSZJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HSJS3_k127_4752098_7	379066.GAU_0136	1.443e-60	218.0	COG0131@1|root,COG0131@2|Bacteria,1ZTHU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HSJS3_k127_4752098_3	379066.GAU_0135	2.4e-97	338.0	COG0107@1|root,COG0107@2|Bacteria,1ZT55@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HSJS3_k127_4752098_8	868864.Dester_1103	1.663e-24	106.0	COG0139@1|root,COG0139@2|Bacteria,2G462@200783|Aquificae	200783|Aquificae	E	belongs to the PRA-CH family	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
HSJS3_k127_4870577_1	1380394.JADL01000024_gene101	8.331e-94	321.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JRCI@204441|Rhodospirillales	204441|Rhodospirillales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
HSJS3_k127_4870577_0	266117.Rxyl_2278	2.39e-102	346.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria,4CSG2@84995|Rubrobacteria	84995|Rubrobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_4870577_2	1254432.SCE1572_12185	3.309e-87	295.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2YYYW@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS3_k127_4883577_0	234267.Acid_4952	3.453e-172	559.0	COG0154@1|root,COG0154@2|Bacteria,3Y3E5@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HSJS3_k127_4883577_9	266117.Rxyl_2863	1.761e-19	96.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
HSJS3_k127_4883577_4	96561.Dole_0431	1.021e-110	377.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper	cumA	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HSJS3_k127_4883577_6	379066.GAU_0945	5.065e-59	216.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
HSJS3_k127_4883577_3	243231.GSU3318	1.038e-134	451.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
HSJS3_k127_4883577_7	861299.J421_2925	1.39e-47	176.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
HSJS3_k127_4883577_2	765914.ThisiDRAFT_0107	2.958e-150	487.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1WXKA@135613|Chromatiales	135613|Chromatiales	G	PFAM Alpha amylase, catalytic	-	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
HSJS3_k127_4883577_1	631362.Thi970DRAFT_01921	1.13e-157	503.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1WXKA@135613|Chromatiales	135613|Chromatiales	G	PFAM Alpha amylase, catalytic	-	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
HSJS3_k127_4883577_5	1121930.AQXG01000010_gene3078	9.251e-87	297.0	COG0668@1|root,COG0668@2|Bacteria,4NH7C@976|Bacteroidetes	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HSJS3_k127_4883577_8	1121930.AQXG01000010_gene3079	5.861e-32	135.0	COG2430@1|root,COG2430@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF432
HSJS3_k127_4900845_4	861299.J421_0915	8.266e-62	222.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_4900845_3	861299.J421_0907	2.833e-89	299.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_4900845_8	273068.TTE0873	0.0008605	49.0	COG3206@1|root,COG3206@2|Bacteria,1V8AX@1239|Firmicutes,25EXZ@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
HSJS3_k127_4900845_6	861299.J421_0905	6.864e-27	126.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HSJS3_k127_4900845_5	1307761.L21SP2_2687	1.567e-35	139.0	COG3439@1|root,COG3439@2|Bacteria,2JAKY@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
HSJS3_k127_4900845_0	292459.STH1757	1.763e-251	818.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HSJS3_k127_4900845_7	207559.Dde_0456	2.514e-05	51.0	COG0810@1|root,COG0810@2|Bacteria,1QEMV@1224|Proteobacteria,436F5@68525|delta/epsilon subdivisions,2X10H@28221|Deltaproteobacteria,2MDXX@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HSJS3_k127_4900845_1	861299.J421_0897	3.12e-171	551.0	COG0031@1|root,COG0031@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HSJS3_k127_4900845_2	349521.HCH_06188	1.467e-94	321.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1XHNJ@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HSJS3_k127_5180335_0	861299.J421_4450	2.432e-51	192.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HSJS3_k127_5180335_1	706587.Desti_4875	4.638e-39	153.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
HSJS3_k127_5180335_2	1379270.AUXF01000001_gene1905	9.855e-31	125.0	COG0405@1|root,COG0405@2|Bacteria,1ZUCB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HSJS3_k127_5352944_1	234267.Acid_0469	2.486e-263	822.0	COG1506@1|root,COG1506@2|Bacteria,3Y3DT@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
HSJS3_k127_5352944_13	1392502.JNIO01000008_gene2022	1.545e-70	243.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H408@909932|Negativicutes	909932|Negativicutes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
HSJS3_k127_5352944_3	379066.GAU_2748	7.389e-189	609.0	COG4188@1|root,COG4188@2|Bacteria,1ZUJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
HSJS3_k127_5352944_32	861299.J421_2391	8.294e-08	59.0	28TV6@1|root,2ZG24@2|Bacteria,1ZV98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5352944_25	357808.RoseRS_1163	2.086e-28	115.0	COG0361@1|root,COG0361@2|Bacteria,2G70W@200795|Chloroflexi,375UY@32061|Chloroflexia	32061|Chloroflexia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HSJS3_k127_5352944_26	1300345.LF41_2696	7.335e-28	119.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HSJS3_k127_5352944_18	661478.OP10G_1964	4.163e-50	200.0	COG0513@1|root,COG0513@2|Bacteria	2|Bacteria	L	helicase activity	deaD	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HSJS3_k127_5352944_30	1231190.NA8A_20552	1.952e-09	66.0	COG2761@1|root,COG2761@2|Bacteria,1RDEK@1224|Proteobacteria	1224|Proteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
HSJS3_k127_5352944_8	667014.Thein_1377	4.042e-90	314.0	COG0436@1|root,COG0436@2|Bacteria,2GGVQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_5352944_15	309807.SRU_0740	2.893e-62	226.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1FJ00@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
HSJS3_k127_5352944_20	869210.Marky_2210	2.12e-45	171.0	COG0394@1|root,COG0394@2|Bacteria,1WJT5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HSJS3_k127_5352944_6	1304275.C41B8_04951	1.557e-103	354.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HSJS3_k127_5352944_21	382464.ABSI01000011_gene2976	1.967e-42	158.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS3_k127_5352944_28	1379698.RBG1_1C00001G0464	2.333e-14	81.0	COG0170@1|root,COG0170@2|Bacteria,2NQ5M@2323|unclassified Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	sec59	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HSJS3_k127_5352944_33	438753.AZC_3566	1.732e-07	60.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2TZSN@28211|Alphaproteobacteria,3F0HW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_7,PAS_9
HSJS3_k127_5352944_11	1381123.AYOD01000001_gene729	1.177e-76	269.0	COG1647@1|root,COG1647@2|Bacteria,1NIYY@1224|Proteobacteria,2U1Z4@28211|Alphaproteobacteria,43IXS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HSJS3_k127_5352944_22	316274.Haur_1893	2.834e-37	143.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HSJS3_k127_5352944_19	861299.J421_0662	2.979e-46	171.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
HSJS3_k127_5352944_17	1457250.BBMO01000001_gene1688	1.494e-54	203.0	COG0702@1|root,arCOG03015@2157|Archaea,2Y1X3@28890|Euryarchaeota,23YEJ@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
HSJS3_k127_5352944_29	1406840.Q763_12110	9.185e-10	69.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,2NSAQ@237|Flavobacterium	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5352944_35	234267.Acid_4526	0.0006531	44.0	COG0577@1|root,COG0577@2|Bacteria,3Y36E@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_5352944_2	1089550.ATTH01000001_gene2023	1.534e-198	640.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1FJQN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HSJS3_k127_5352944_14	404589.Anae109_0937	2.181e-69	246.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
HSJS3_k127_5352944_12	404589.Anae109_0938	5.643e-76	270.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
HSJS3_k127_5352944_0	404589.Anae109_0939	5.194e-291	919.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
HSJS3_k127_5352944_7	861299.J421_2830	6.47e-93	338.0	COG1629@1|root,COG4771@2|Bacteria,1ZU8C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
HSJS3_k127_5352944_34	861299.J421_2829	0.0002892	54.0	2F5V8@1|root,33YE7@2|Bacteria,1ZUZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
HSJS3_k127_5352944_16	861299.J421_4361	1.098e-56	206.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HSJS3_k127_5352944_31	1230342.CTM_01609	6.571e-08	61.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes	1239|Firmicutes	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,T2SSG
HSJS3_k127_5352944_23	861299.J421_3698	4.934e-37	149.0	COG2967@1|root,COG2967@2|Bacteria,1ZTR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
HSJS3_k127_5352944_4	665571.STHERM_c03590	4.167e-159	520.0	COG3044@1|root,COG3044@2|Bacteria	2|Bacteria	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
HSJS3_k127_5352944_10	1265313.HRUBRA_00646	8.962e-77	265.0	COG1024@1|root,COG1024@2|Bacteria,1MVA6@1224|Proteobacteria,1S5M4@1236|Gammaproteobacteria,1JBVT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
HSJS3_k127_5352944_5	243090.RB1381	3.334e-127	417.0	COG1899@1|root,COG1899@2|Bacteria,2IWZ8@203682|Planctomycetes	203682|Planctomycetes	O	COG1899 Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
HSJS3_k127_5352944_24	1144305.PMI02_03956	2.212e-31	129.0	COG2350@1|root,COG2350@2|Bacteria,1MZ8Y@1224|Proteobacteria,2UHFW@28211|Alphaproteobacteria,2KB02@204457|Sphingomonadales	204457|Sphingomonadales	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
HSJS3_k127_5352944_27	861299.J421_2919	8.256e-24	114.0	COG1629@1|root,COG1629@2|Bacteria,1ZTI4@142182|Gemmatimonadetes	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Caps_assemb_Wzi
HSJS3_k127_5352944_9	382464.ABSI01000020_gene125	3.75e-80	281.0	COG0471@1|root,COG0471@2|Bacteria,46UA9@74201|Verrucomicrobia,2ITKW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
HSJS3_k127_5376109_7	518766.Rmar_2563	2.339e-42	167.0	COG0707@1|root,COG0707@2|Bacteria,4PKSS@976|Bacteroidetes,1FIZE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
HSJS3_k127_5376109_2	861299.J421_0796	1.409e-115	383.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HSJS3_k127_5376109_1	861299.J421_2666	1.255e-126	421.0	COG0508@1|root,COG0508@2|Bacteria,1ZSYJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HSJS3_k127_5376109_0	1280944.HY17_15580	4.162e-127	413.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,43W9A@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
HSJS3_k127_5376109_4	861299.J421_2668	4.211e-102	343.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HSJS3_k127_5376109_3	671143.DAMO_1599	6.884e-112	374.0	COG0320@1|root,COG0320@2|Bacteria,2NNPI@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HSJS3_k127_5376109_5	266117.Rxyl_2215	2.189e-91	307.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CQ3Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HSJS3_k127_5376109_6	886293.Sinac_6848	4.575e-45	176.0	COG0451@1|root,COG0451@2|Bacteria,2J2KW@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HSJS3_k127_5376109_8	861299.J421_0446	4.782e-11	69.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5419756_0	1121439.dsat_0582	2.08e-88	308.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2M9JU@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
HSJS3_k127_5419756_1	1122621.ATZA01000036_gene3422	5.724e-05	46.0	COG0624@1|root,COG0624@2|Bacteria,4NJN0@976|Bacteroidetes,1IP8H@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HSJS3_k127_5443051_0	861299.J421_3281	2.651e-158	512.0	COG1109@1|root,COG1109@2|Bacteria,1ZSP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HSJS3_k127_5443051_3	498761.HM1_2565	1.175e-124	434.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0182	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
HSJS3_k127_5443051_1	1379270.AUXF01000006_gene245	1.392e-154	497.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HSJS3_k127_5443051_2	1379270.AUXF01000006_gene246	9.411e-130	419.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
HSJS3_k127_5443051_8	861299.J421_3277	3.076e-18	92.0	COG0517@1|root,COG1762@1|root,COG0517@2|Bacteria,COG1762@2|Bacteria,1ZUGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	CBS,PTS_EIIA_2
HSJS3_k127_5443051_6	1379270.AUXF01000006_gene247	3.192e-50	182.0	COG0105@1|root,COG0105@2|Bacteria,1ZTTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NDK	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HSJS3_k127_5443051_7	861299.J421_3275	8.36e-23	104.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HSJS3_k127_5443051_9	316067.Geob_2610	2.971e-15	76.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HSJS3_k127_5443051_4	861299.J421_3273	6.588e-92	313.0	COG0416@1|root,COG0416@2|Bacteria,1ZSN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HSJS3_k127_5443051_5	1121930.AQXG01000003_gene2731	1.452e-53	194.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HSJS3_k127_5457551_3	1121930.AQXG01000010_gene3058	1.882e-14	79.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_5457551_1	1291050.JAGE01000002_gene3640	8.578e-68	236.0	COG0500@1|root,COG2226@2|Bacteria,1V20J@1239|Firmicutes,24BSI@186801|Clostridia	186801|Clostridia	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HSJS3_k127_5457551_0	1249627.D779_1354	3.864e-149	486.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
HSJS3_k127_5457551_4	1445613.JALM01000020_gene4852	8.955e-10	64.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
HSJS3_k127_5457551_2	240015.ACP_0608	2.942e-62	224.0	COG0077@1|root,COG0077@2|Bacteria,3Y49H@57723|Acidobacteria,2JJ3X@204432|Acidobacteriia	204432|Acidobacteriia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
HSJS3_k127_5539368_1	287.DR97_3909	7.885e-62	223.0	COG1028@1|root,COG1028@2|Bacteria,1QTU9@1224|Proteobacteria,1T1HD@1236|Gammaproteobacteria,1YKZ2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS3_k127_5539368_7	196162.Noca_1783	1.376e-06	57.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_3
HSJS3_k127_5539368_6	667015.Bacsa_0441	2.929e-13	79.0	COG0666@1|root,COG0666@2|Bacteria,4NXSH@976|Bacteroidetes,2FM5T@200643|Bacteroidia,4AMUZ@815|Bacteroidaceae	976|Bacteroidetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4
HSJS3_k127_5539368_4	880073.Calab_3376	8.973e-51	186.0	COG3295@1|root,COG3295@2|Bacteria	2|Bacteria	C	Protein conserved in bacteria	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM,PepSY_TM_like_2
HSJS3_k127_5539368_2	378806.STAUR_5358	2.071e-60	231.0	COG1729@1|root,COG1729@2|Bacteria,1N780@1224|Proteobacteria,42V4V@68525|delta/epsilon subdivisions,2WR6U@28221|Deltaproteobacteria,2YW0N@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5539368_3	1237149.C900_02705	3.735e-53	192.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47PG1@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K01802,ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HSJS3_k127_5539368_0	234267.Acid_1953	0.0	1024.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5737990_2	861299.J421_2873	2.547e-92	326.0	COG0166@1|root,COG0166@2|Bacteria,1ZU5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HSJS3_k127_5737990_3	861299.J421_2872	7.223e-80	278.0	COG1235@1|root,COG1235@2|Bacteria,1ZT49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
HSJS3_k127_5737990_0	861299.J421_2871	4.096e-133	450.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HSJS3_k127_5737990_4	861299.J421_2109	1.453e-78	282.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
HSJS3_k127_5737990_6	861299.J421_3049	1.791e-45	169.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
HSJS3_k127_5737990_7	379066.GAU_0167	2.502e-24	106.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
HSJS3_k127_5737990_1	1121346.KB899812_gene2043	2.1e-123	403.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,275IX@186822|Paenibacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HSJS3_k127_5737990_5	596327.PORUE0001_1737	1.412e-60	220.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,2FN1C@200643|Bacteroidia,22X6Y@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HSJS3_k127_5737990_8	1379270.AUXF01000004_gene3086	8.544e-05	47.0	COG0457@1|root,COG0457@2|Bacteria,1ZTR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5880988_4	1123278.KB893560_gene3115	1.45e-24	105.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47N4P@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HSJS3_k127_5880988_0	1121920.AUAU01000013_gene1698	5.64e-296	925.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
HSJS3_k127_5880988_5	246197.MXAN_0696	6.086e-06	52.0	COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria	1224|Proteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_5880988_3	1230457.C476_15800	1.411e-70	245.0	COG0819@1|root,arCOG01128@2157|Archaea,2XTG7@28890|Euryarchaeota,23STS@183963|Halobacteria	183963|Halobacteria	K	transcription activator	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
HSJS3_k127_5880988_1	861299.J421_3694	2.912e-255	806.0	COG2183@1|root,COG2183@2|Bacteria,1ZSMQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Tex-like protein N-terminal domain	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HSJS3_k127_5880988_2	502025.Hoch_1692	1.221e-97	332.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria	1224|Proteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.310	ko:K16843	ko00270,map00270	-	R05693	RC00031	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HSJS3_k127_5945756_0	232721.Ajs_2164	1.816e-314	981.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHNJ@28216|Betaproteobacteria,4AGI0@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HSJS3_k127_5945756_9	243231.GSU2317	2.054e-123	427.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,43S4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
HSJS3_k127_5945756_22	29306.JOBE01000001_gene2614	6.678e-46	182.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HSJS3_k127_5945756_8	1379270.AUXF01000001_gene2645	4.342e-166	559.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HSJS3_k127_5945756_4	1379270.AUXF01000004_gene3297	2.849e-197	634.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
HSJS3_k127_5945756_3	1379698.RBG1_1C00001G0629	1.707e-206	661.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
HSJS3_k127_5945756_33	1335760.ASTG01000001_gene3000	7.002e-05	48.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,2UCEY@28211|Alphaproteobacteria,2K7ZX@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
HSJS3_k127_5945756_30	1121004.ATVC01000022_gene1699	9.136e-19	91.0	2CGNP@1|root,32S4A@2|Bacteria,1N1J7@1224|Proteobacteria,2VUN9@28216|Betaproteobacteria,2KRN5@206351|Neisseriales	206351|Neisseriales	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5945756_34	1078020.KEK_02356	0.0002695	50.0	COG3631@1|root,COG3631@2|Bacteria,2IT24@201174|Actinobacteria,23AMY@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HSJS3_k127_5945756_14	379066.GAU_2316	4.106e-83	296.0	COG3836@1|root,COG3836@2|Bacteria,1ZU9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
HSJS3_k127_5945756_13	1120705.FG95_02625	3.114e-89	311.0	COG1228@1|root,COG1228@2|Bacteria,1R86X@1224|Proteobacteria,2U400@28211|Alphaproteobacteria,2K1TI@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_5945756_24	296591.Bpro_1055	6.347e-44	171.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,4ABG9@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	Lactamase_B,NUDIX
HSJS3_k127_5945756_5	861299.J421_2136	9.353e-189	605.0	COG0405@1|root,COG0405@2|Bacteria,1ZUCB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HSJS3_k127_5945756_23	706587.Desti_4875	9.332e-45	171.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
HSJS3_k127_5945756_2	1121382.JQKG01000017_gene1834	1.949e-239	769.0	COG0466@1|root,COG0466@2|Bacteria,1WISX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HSJS3_k127_5945756_12	2074.JNYD01000022_gene1521	1.88e-99	334.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4DYK1@85010|Pseudonocardiales	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HSJS3_k127_5945756_18	489825.LYNGBM3L_07050	1.879e-65	233.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H8P0@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
HSJS3_k127_5945756_26	215803.DB30_0168	3.288e-38	160.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
HSJS3_k127_5945756_29	1379270.AUXF01000007_gene972	2.823e-27	114.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_5945756_32	1121440.AUMA01000008_gene847	7.034e-06	51.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria,2MBM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
HSJS3_k127_5945756_19	1122176.KB903532_gene2524	4.519e-63	235.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1IVD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5945756_10	926566.Terro_2774	2.401e-100	337.0	COG0492@1|root,COG0492@2|Bacteria,3Y2NX@57723|Acidobacteria,2JI8S@204432|Acidobacteriia	204432|Acidobacteriia	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
HSJS3_k127_5945756_6	688270.Celal_0295	8.758e-171	564.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_5945756_17	316274.Haur_0795	1.553e-72	259.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,LuxE
HSJS3_k127_5945756_21	1134413.ANNK01000094_gene900	6.483e-48	196.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,1ZCXK@1386|Bacillus	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
HSJS3_k127_5945756_15	1198114.AciX9_0727	2.252e-79	276.0	COG4152@1|root,COG4152@2|Bacteria,3Y2NV@57723|Acidobacteria,2JHVX@204432|Acidobacteriia	204432|Acidobacteriia	S	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HSJS3_k127_5945756_20	518766.Rmar_2404	6.435e-59	223.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1FIJ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HSJS3_k127_5945756_28	1210045.ALNP01000002_gene4181	1.174e-29	134.0	COG1999@1|root,COG1999@2|Bacteria,2GKF0@201174|Actinobacteria	201174|Actinobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HSJS3_k127_5945756_16	502025.Hoch_6586	1.503e-74	279.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2Z315@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
HSJS3_k127_5945756_25	321332.CYB_0462	7.086e-41	168.0	COG1721@1|root,COG1721@2|Bacteria,1G15B@1117|Cyanobacteria,1GZR9@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS3_k127_5945756_11	321327.CYA_1224	3.106e-100	341.0	COG0714@1|root,COG0714@2|Bacteria,1G1CG@1117|Cyanobacteria,1GZ7G@1129|Synechococcus	1117|Cyanobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS3_k127_5945756_27	861299.J421_3631	1.99e-36	146.0	COG2010@1|root,COG2010@2|Bacteria,1ZTKA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
HSJS3_k127_5945756_1	861299.J421_3630	1.034e-239	775.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
HSJS3_k127_5945756_7	379066.GAU_2035	2.703e-170	550.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HSJS3_k127_5945756_31	404589.Anae109_0843	3.876e-06	52.0	COG2010@1|root,COG2010@2|Bacteria,1NDP7@1224|Proteobacteria,43BBN@68525|delta/epsilon subdivisions,2X6QV@28221|Deltaproteobacteria,2Z02F@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
HSJS3_k127_5963509_2	215803.DB30_8370	6.434e-139	478.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_5963509_5	234267.Acid_4721	5.475e-25	111.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HSJS3_k127_5963509_3	880073.Calab_2443	7.649e-96	324.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_5963509_0	1379270.AUXF01000002_gene1243	1.782e-185	599.0	COG0488@1|root,COG0488@2|Bacteria,1ZSV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
HSJS3_k127_5963509_4	1041930.Mtc_1406	3.529e-38	151.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
HSJS3_k127_5963509_1	1144275.COCOR_03147	1.045e-139	458.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,4360M@68525|delta/epsilon subdivisions,2X2HZ@28221|Deltaproteobacteria,2Z0WC@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HSJS3_k127_5963509_6	1122609.AUGT01000018_gene109	0.0001736	54.0	COG3468@1|root,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,CHAP,TIG
HSJS3_k127_5967680_3	861299.J421_0290	5.795e-74	260.0	COG0845@1|root,COG0845@2|Bacteria,1ZUP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
HSJS3_k127_5967680_4	861299.J421_2904	2.985e-58	222.0	COG1538@1|root,COG1538@2|Bacteria,1ZSMB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HSJS3_k127_5967680_7	1122179.KB890440_gene1034	3.227e-29	126.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1IXPF@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
HSJS3_k127_5967680_2	518766.Rmar_2509	1.981e-115	383.0	COG0812@1|root,COG0812@2|Bacteria,4PEBS@976|Bacteroidetes,1FISG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
HSJS3_k127_5967680_1	861299.J421_0332	4.851e-116	404.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0332|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5967680_6	861299.J421_3999	1.634e-46	186.0	COG0400@1|root,COG0400@2|Bacteria,1ZTYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5967680_5	638303.Thal_1464	2.253e-56	208.0	COG1898@1|root,COG1898@2|Bacteria,2G3ZK@200783|Aquificae	200783|Aquificae	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
HSJS3_k127_5967680_0	1379270.AUXF01000006_gene146	2.326e-123	413.0	COG0534@1|root,COG0534@2|Bacteria,1ZUAU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HSJS3_k127_5967680_8	448385.sce5230	0.0003354	48.0	COG2050@1|root,COG2050@2|Bacteria,1RHAN@1224|Proteobacteria,43157@68525|delta/epsilon subdivisions,2WWIW@28221|Deltaproteobacteria,2YVGQ@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
HSJS3_k127_5968141_0	1232683.ADIMK_2406	9.015e-195	617.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4643G@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HSJS3_k127_5968141_1	1382359.JIAL01000001_gene2880	9.173e-22	109.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
HSJS3_k127_6062228_4	1379270.AUXF01000002_gene1323	1.051e-70	261.0	COG3170@1|root,COG3291@1|root,COG3170@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBM_6,GSDH,He_PIG,Malectin,PKD,Secretin,T2SS-T3SS_pil_N,VCBS,fn3
HSJS3_k127_6062228_6	748727.CLJU_c15530	5.664e-55	204.0	COG1404@1|root,COG1404@2|Bacteria,1UFB1@1239|Firmicutes,24DCR@186801|Clostridia,36H0Y@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HSJS3_k127_6062228_7	234267.Acid_3601	2.585e-42	166.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
HSJS3_k127_6062228_0	1121104.AQXH01000001_gene1406	3.679e-177	587.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_6062228_3	1078085.HMPREF1210_01416	3.717e-92	333.0	COG0842@1|root,COG0842@2|Bacteria,1UNMI@1239|Firmicutes,4IUIA@91061|Bacilli	91061|Bacilli	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6062228_1	304371.MCP_1300	1.083e-119	392.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HSJS3_k127_6062228_8	298654.FraEuI1c_1435	1.577e-35	148.0	2AMVA@1|root,31CS1@2|Bacteria,2IG5A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6062228_5	870187.Thini_4391	4.761e-57	213.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,NHL,TIG
HSJS3_k127_6062228_2	251221.35211765	1.324e-119	418.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_6062228_9	861299.J421_6140	1.122e-19	93.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_6062228_10	1379270.AUXF01000005_gene585	4.922e-11	62.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HSJS3_k127_6139412_10	875328.JDM601_0616	3.365e-21	106.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,2GMX8@201174|Actinobacteria,235G4@1762|Mycobacteriaceae	201174|Actinobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,PDDEXK_1,RNase_H_2
HSJS3_k127_6139412_7	502025.Hoch_5381	7.458e-50	188.0	COG4221@1|root,COG4221@2|Bacteria,1QVTE@1224|Proteobacteria	1224|Proteobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	yueD	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS3_k127_6139412_6	326424.FRAAL1397	1.482e-57	214.0	2CF7S@1|root,2ZB6P@2|Bacteria,2H77W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6139412_14	926569.ANT_07310	4.104e-09	68.0	COG0500@1|root,COG0537@1|root,COG0500@2|Bacteria,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi	200795|Chloroflexi	FG	Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT,NUDIX
HSJS3_k127_6139412_12	1385521.N803_13240	1.102e-13	75.0	COG3742@1|root,COG3742@2|Bacteria,2IS39@201174|Actinobacteria,4FJ3T@85021|Intrasporangiaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
HSJS3_k127_6139412_2	1081640.AGFU01000045_gene614	3.162e-116	396.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2K0M0@204457|Sphingomonadales	204457|Sphingomonadales	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
HSJS3_k127_6139412_3	865937.Gilli_1295	1.612e-112	379.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia,2P7G2@244698|Gillisia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_6139412_11	196490.AUEZ01000005_gene3658	2.747e-14	84.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQS8@28211|Alphaproteobacteria,3JXE1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
HSJS3_k127_6139412_8	485915.Dret_0514	1.49e-48	180.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MBEX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
HSJS3_k127_6139412_0	309807.SRU_2720	1.991e-183	607.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
HSJS3_k127_6139412_9	1254432.SCE1572_45490	1.019e-27	119.0	COG3409@1|root,COG3409@2|Bacteria,1Q95M@1224|Proteobacteria,43760@68525|delta/epsilon subdivisions,2X24E@28221|Deltaproteobacteria,2Z001@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6139412_5	497964.CfE428DRAFT_3322	1.605e-90	311.0	COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
HSJS3_k127_6139412_13	870187.Thini_3841	2.2e-12	75.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6139412_4	205922.Pfl01_3893	8.57e-106	351.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria,1YPWK@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
HSJS3_k127_6139412_1	1089550.ATTH01000001_gene1191	3.332e-165	533.0	COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes	976|Bacteroidetes	H	sulfatase	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
HSJS3_k127_6199758_0	1429851.X548_10080	2.811e-07	61.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,1SG73@1236|Gammaproteobacteria,1X5NU@135614|Xanthomonadales	135614|Xanthomonadales	M	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta,He_PIG
HSJS3_k127_6387754_2	1280949.HAD_14109	4.212e-177	563.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	MA20_01050	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3
HSJS3_k127_6387754_1	861299.J421_0440	9.221e-192	619.0	COG2304@1|root,COG2304@2|Bacteria,1ZSKK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
HSJS3_k127_6387754_0	1313172.YM304_27660	3.94e-213	689.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
HSJS3_k127_6387754_12	314345.SPV1_07149	0.0003385	50.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria	1224|Proteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	gppA	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643	HD,Ppx-GppA
HSJS3_k127_6387754_6	1501230.ET33_18720	2.925e-91	312.0	COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,26QIZ@186822|Paenibacillaceae	91061|Bacilli	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HSJS3_k127_6387754_3	518766.Rmar_1911	2.982e-157	509.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HSJS3_k127_6387754_8	1379270.AUXF01000004_gene3199	1.379e-67	243.0	COG3342@1|root,COG3342@2|Bacteria,1ZUFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
HSJS3_k127_6387754_5	1121104.AQXH01000003_gene384	3.058e-127	418.0	COG2421@1|root,COG2421@2|Bacteria,4NKD7@976|Bacteroidetes	976|Bacteroidetes	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
HSJS3_k127_6387754_4	479434.Sthe_1822	3.135e-142	483.0	COG0154@1|root,COG0154@2|Bacteria,2G82J@200795|Chloroflexi,27XKT@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HSJS3_k127_6387754_10	2340.JV46_21820	1.165e-24	104.0	2FDFA@1|root,345GY@2|Bacteria,1P1RR@1224|Proteobacteria,1SVK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6387754_7	1089551.KE386572_gene3150	3.103e-68	243.0	COG2518@1|root,COG2518@2|Bacteria,1QURA@1224|Proteobacteria,2TW4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
HSJS3_k127_6387754_9	861299.J421_1911	3.688e-31	124.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HSJS3_k127_6392180_9	1379270.AUXF01000007_gene949	1.609e-11	71.0	COG0723@1|root,COG0723@2|Bacteria,1ZUKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
HSJS3_k127_6392180_5	1379270.AUXF01000001_gene2741	1.124e-95	323.0	COG3342@1|root,COG3342@2|Bacteria,1ZUQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
HSJS3_k127_6392180_8	1537715.JQFJ01000002_gene2184	1.824e-20	93.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2TSWU@28211|Alphaproteobacteria,2K50T@204457|Sphingomonadales	204457|Sphingomonadales	L	UreE urease accessory protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UDG
HSJS3_k127_6392180_6	1125863.JAFN01000001_gene1580	7.252e-72	256.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
HSJS3_k127_6392180_4	234267.Acid_2447	7.418e-101	342.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
HSJS3_k127_6392180_1	1237149.C900_05343	1.938e-180	578.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47K4A@768503|Cytophagia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	gabD	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HSJS3_k127_6392180_0	56780.SYN_02082	9.751e-281	897.0	COG0744@1|root,COG5009@1|root,COG0744@2|Bacteria,COG5009@2|Bacteria,1NRPB@1224|Proteobacteria,42ZB6@68525|delta/epsilon subdivisions,2WTUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
HSJS3_k127_6392180_2	1123276.KB893268_gene5037	3.202e-156	507.0	COG1249@1|root,COG1249@2|Bacteria,4NEMS@976|Bacteroidetes,47KQ1@768503|Cytophagia	976|Bacteroidetes	C	Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0)	merA	-	-	ko:K21739	-	-	-	-	ko00000	-	-	-	Pyr_redox_2,Pyr_redox_dim
HSJS3_k127_6392180_7	861299.J421_2070	1.536e-47	178.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
HSJS3_k127_6392180_3	1379270.AUXF01000003_gene3619	8.306e-119	395.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_640603_1	234267.Acid_1951	1.037e-260	833.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
HSJS3_k127_640603_17	1265313.HRUBRA_00995	4.052e-09	59.0	2DZZ5@1|root,32VNT@2|Bacteria,1MZ40@1224|Proteobacteria,1SMUW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_640603_10	518766.Rmar_0717	2.136e-64	235.0	COG1506@1|root,COG1506@2|Bacteria,4P5XA@976|Bacteroidetes	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_640603_15	1041146.ATZB01000029_gene5429	1.466e-19	96.0	COG1309@1|root,COG1309@2|Bacteria,1PZQF@1224|Proteobacteria,2UZQA@28211|Alphaproteobacteria,4BJUY@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HSJS3_k127_640603_6	1379270.AUXF01000002_gene1448	2.502e-101	338.0	COG3340@1|root,COG3340@2|Bacteria,1ZUA9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
HSJS3_k127_640603_5	1192759.AKIB01000027_gene2114	1.919e-114	378.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,2KA1H@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
HSJS3_k127_640603_8	479433.Caci_0748	4.157e-68	241.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_640603_0	204669.Acid345_1384	5.174e-289	904.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HSJS3_k127_640603_3	1210884.HG799466_gene12573	9.442e-125	407.0	COG0479@1|root,COG0479@2|Bacteria,2J136@203682|Planctomycetes	203682|Planctomycetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
HSJS3_k127_640603_12	1210884.HG799466_gene12574	6.927e-42	160.0	2EDAV@1|root,33776@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_640603_11	478741.JAFS01000001_gene1850	1.41e-62	229.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia,37GE9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
HSJS3_k127_640603_14	682795.AciX8_4833	1.446e-20	97.0	COG1695@1|root,COG1695@2|Bacteria,3Y8CC@57723|Acidobacteria,2JP3G@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_640603_4	861299.J421_2272	1.751e-122	429.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_640603_7	391625.PPSIR1_13430	1.088e-68	241.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2WS0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
HSJS3_k127_640603_13	935863.AWZR01000004_gene672	2.032e-38	152.0	COG4319@1|root,COG4319@2|Bacteria,1N361@1224|Proteobacteria,1S9P8@1236|Gammaproteobacteria,1X7TS@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_3
HSJS3_k127_640603_2	861299.J421_1357	2.645e-160	514.0	COG2159@1|root,COG2159@2|Bacteria,1ZSR7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
HSJS3_k127_640603_9	379066.GAU_3786	2.991e-66	241.0	COG0488@1|root,COG0488@2|Bacteria,1ZTBH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HSJS3_k127_6543141_6	404589.Anae109_1755	2.934e-59	216.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HSJS3_k127_6543141_0	379066.GAU_1492	0.0	1101.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HSJS3_k127_6543141_8	203275.BFO_0966	4.442e-31	134.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22XX8@171551|Porphyromonadaceae	976|Bacteroidetes	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HSJS3_k127_6543141_7	379066.GAU_1250	6.946e-37	141.0	COG3118@1|root,COG3118@2|Bacteria,1ZTS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HSJS3_k127_6543141_4	861299.J421_2975	6.296e-70	246.0	COG0313@1|root,COG0313@2|Bacteria,1ZTK1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HSJS3_k127_6543141_3	861299.J421_2976	1.209e-77	265.0	COG1657@1|root,COG1657@2|Bacteria,1ZSPV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
HSJS3_k127_6543141_5	1379270.AUXF01000005_gene566	1.938e-62	246.0	COG1196@1|root,COG1196@2|Bacteria,1ZSU8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6543141_9	861299.J421_2978	2.234e-18	101.0	COG1729@1|root,COG1729@2|Bacteria,1ZTBJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	-
HSJS3_k127_6543141_1	861299.J421_2979	2.442e-153	499.0	2CD20@1|root,2Z7SQ@2|Bacteria,1ZTFE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6543141_2	861299.J421_2981	3.742e-94	321.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1ZT1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RadC
HSJS3_k127_6698939_8	1215092.PA6_010_00160	7.364e-110	366.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RYET@1236|Gammaproteobacteria,1YF03@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
HSJS3_k127_6698939_15	861299.J421_0777	6.826e-38	147.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
HSJS3_k127_6698939_3	1125971.ASJB01000065_gene6243	8.916e-130	441.0	COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria,4E19E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_6698939_11	1128421.JAGA01000002_gene1518	3.23e-91	322.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
HSJS3_k127_6698939_10	1122939.ATUD01000011_gene2213	2.778e-93	314.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HSJS3_k127_6698939_4	379066.GAU_0452	6.058e-127	434.0	COG0744@1|root,COG0744@2|Bacteria,1ZSUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HSJS3_k127_6698939_7	1121439.dsat_0040	1.772e-114	387.0	COG0391@1|root,COG0391@2|Bacteria,1NW3K@1224|Proteobacteria,42QAP@68525|delta/epsilon subdivisions,2WIZS@28221|Deltaproteobacteria,2M7XZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0052	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
HSJS3_k127_6698939_1	1121930.AQXG01000011_gene1722	3.739e-165	538.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
HSJS3_k127_6698939_13	1144275.COCOR_02130	1.067e-46	177.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria	1224|Proteobacteria	J	endoribonuclease L-PSP	ridA	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HSJS3_k127_6698939_0	1121930.AQXG01000011_gene1720	3.095e-213	678.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HSJS3_k127_6698939_17	861299.J421_3108	9.454e-32	138.0	2F044@1|root,33T7T@2|Bacteria,1ZTDC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6698939_18	84531.JMTZ01000024_gene4034	2.726e-30	135.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S9VR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HSJS3_k127_6698939_9	671143.DAMO_1554	3.547e-102	360.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HSJS3_k127_6698939_12	329726.AM1_2306	2.599e-82	282.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
HSJS3_k127_6698939_2	1121930.AQXG01000003_gene2654	4.18e-130	436.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1IPCU@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HSJS3_k127_6698939_19	1122169.AREN01000004_gene465	1.649e-21	106.0	COG2120@1|root,COG2204@1|root,COG2120@2|Bacteria,COG2204@2|Bacteria,1MUTM@1224|Proteobacteria,1S2K7@1236|Gammaproteobacteria,1JFW1@118969|Legionellales	118969|Legionellales	T	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L,Response_reg
HSJS3_k127_6698939_5	309807.SRU_1894	1.55e-120	407.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1FJEG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
HSJS3_k127_6698939_6	1396141.BATP01000006_gene5499	7.222e-116	381.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia,2IU0V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACCA
HSJS3_k127_6698939_16	861299.J421_2654	1.169e-33	139.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
HSJS3_k127_6706113_5	861299.J421_3009	4.17e-27	128.0	COG0611@1|root,COG0611@2|Bacteria,1ZTIU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HSJS3_k127_6706113_3	1232410.KI421415_gene3033	1.758e-71	261.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,43T92@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HSJS3_k127_6706113_6	861299.J421_3007	1.144e-26	111.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6706113_4	861299.J421_3006	5.295e-35	142.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6706113_0	1232410.KI421413_gene687	2.651e-173	557.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43SDW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Serine hydroxymethyltransferase	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HSJS3_k127_6706113_1	1329516.JPST01000036_gene3052	1.791e-120	396.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27BNG@186824|Thermoactinomycetaceae	91061|Bacilli	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HSJS3_k127_6706113_2	861299.J421_3003	2.205e-97	331.0	COG1960@1|root,COG1960@2|Bacteria,1ZSRC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_6712228_4	29875.EHK25674	3.252e-08	56.0	2AAWD@1|root,2SAUR@2759|Eukaryota,39YPR@33154|Opisthokonta,3NYJM@4751|Fungi,3R1JE@4890|Ascomycota,215RQ@147550|Sordariomycetes,3TK7W@5125|Hypocreales	4751|Fungi	E	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
HSJS3_k127_6712228_3	1502850.FG91_02996	2.534e-22	103.0	2AAWD@1|root,3109H@2|Bacteria,1N31N@1224|Proteobacteria	1224|Proteobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
HSJS3_k127_6712228_0	448385.sce5442	2.07e-140	459.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,42YEF@68525|delta/epsilon subdivisions,2WU92@28221|Deltaproteobacteria,2YYRX@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
HSJS3_k127_6712228_2	1267535.KB906767_gene1277	3.142e-52	208.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
HSJS3_k127_6712228_1	215803.DB30_8370	7.922e-56	209.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_6734907_0	861299.J421_3857	1.114e-235	752.0	COG0466@1|root,COG0466@2|Bacteria,1ZT5P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HSJS3_k127_6734907_14	696281.Desru_1009	3.869e-48	194.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,261YZ@186807|Peptococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HSJS3_k127_6734907_24	1379270.AUXF01000003_gene3510	9.052e-15	87.0	2F4EZ@1|root,33X55@2|Bacteria,1ZTSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6734907_7	379066.GAU_2498	1.549e-128	436.0	COG2204@1|root,COG2204@2|Bacteria,1ZSWY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
HSJS3_k127_6734907_16	861299.J421_3956	5.093e-46	176.0	COG0521@1|root,COG0521@2|Bacteria,1ZU2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
HSJS3_k127_6734907_8	861299.J421_3957	9.829e-123	411.0	COG0404@1|root,COG0404@2|Bacteria,1ZTBZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HSJS3_k127_6734907_9	861299.J421_3960	1.846e-116	396.0	COG0078@1|root,COG0078@2|Bacteria,1ZT4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HSJS3_k127_6734907_3	1379270.AUXF01000003_gene3408	3.444e-186	593.0	COG1220@1|root,COG1220@2|Bacteria,1ZSVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
HSJS3_k127_6734907_13	861299.J421_3964	2.811e-72	248.0	COG5405@1|root,COG5405@2|Bacteria,1ZSVH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
HSJS3_k127_6734907_12	861299.J421_3967	2.617e-83	286.0	COG4974@1|root,COG4974@2|Bacteria,1ZT3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HSJS3_k127_6734907_6	1382358.JHVN01000004_gene2488	2.871e-137	458.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,21W8W@150247|Anoxybacillus	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
HSJS3_k127_6734907_2	1123393.KB891332_gene2768	8.958e-209	677.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1KSKD@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
HSJS3_k127_6734907_20	264732.Moth_1556	2.209e-30	127.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,42GWP@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
HSJS3_k127_6734907_5	861299.J421_3974	8.052e-139	455.0	COG0082@1|root,COG0082@2|Bacteria,1ZT39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HSJS3_k127_6734907_11	861299.J421_3976	2.477e-114	390.0	COG4796@1|root,COG4796@2|Bacteria,1ZSRT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	AMIN domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
HSJS3_k127_6734907_25	1397528.Q671_16250	7.593e-06	56.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1XJVN@135619|Oceanospirillales	135619|Oceanospirillales	NU	Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
HSJS3_k127_6734907_21	379066.GAU_2517	2.395e-26	117.0	COG3166@1|root,COG3166@2|Bacteria,1ZTR8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Fimbrial assembly protein (PilN)	-	-	-	-	-	-	-	-	-	-	-	-	PilN
HSJS3_k127_6734907_10	379066.GAU_2518	1.183e-115	381.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
HSJS3_k127_6734907_22	861299.J421_6360	9.289e-26	122.0	2F0M3@1|root,33TPR@2|Bacteria,1ZUAZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6734907_26	1163407.UU7_01912	2.265e-05	56.0	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1S3DY@1236|Gammaproteobacteria,1X6P5@135614|Xanthomonadales	135614|Xanthomonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
HSJS3_k127_6734907_29	1123393.KB891316_gene1149	0.0008308	50.0	COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,2VX03@28216|Betaproteobacteria,1KTHP@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HSJS3_k127_6734907_1	861299.J421_2007	6.176e-227	738.0	COG4262@1|root,COG4262@2|Bacteria,1ZU7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
HSJS3_k127_6734907_27	1157708.KB907450_gene5380	5.102e-05	52.0	COG4970@1|root,COG4970@2|Bacteria,1RK57@1224|Proteobacteria,2VTNI@28216|Betaproteobacteria,4AEBB@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
HSJS3_k127_6734907_4	448385.sce2881	2.578e-139	461.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
HSJS3_k127_6734907_15	243231.GSU2042	1.802e-46	186.0	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,43RXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HSJS3_k127_6734907_18	1379270.AUXF01000002_gene1199	8.033e-33	132.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HSJS3_k127_6734907_23	861299.J421_1152	9.953e-23	102.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HSJS3_k127_6734907_19	45351.EDO43484	1.31e-32	147.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa	33208|Metazoa	C	positive regulation of proteasomal protein catabolic process	TMTC4	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
HSJS3_k127_6734907_17	1125863.JAFN01000001_gene2892	2.449e-35	137.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
HSJS3_k127_6740563_7	204669.Acid345_2395	1.339e-77	274.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
HSJS3_k127_6740563_6	472759.Nhal_1409	2.436e-78	270.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,1S2XY@1236|Gammaproteobacteria,1WYES@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_6740563_0	383372.Rcas_1858	1.348e-228	744.0	COG0577@1|root,COG0577@2|Bacteria,2G6IW@200795|Chloroflexi,374ZQ@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_6740563_5	1242864.D187_001016	1.739e-114	413.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
HSJS3_k127_6740563_9	1232410.KI421428_gene1021	2.984e-25	115.0	COG0011@1|root,COG0011@2|Bacteria,1N2GU@1224|Proteobacteria,42UPF@68525|delta/epsilon subdivisions,2WR94@28221|Deltaproteobacteria,43W2X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
HSJS3_k127_6740563_2	1265313.HRUBRA_00684	1.247e-173	557.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,1RP3N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	amidohydrolase	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HSJS3_k127_6740563_11	1296415.JACC01000026_gene1733	4.82e-21	107.0	COG3391@1|root,COG3391@2|Bacteria,4NWE6@976|Bacteroidetes,1I650@117743|Flavobacteriia,2YI2P@290174|Aquimarina	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,SGL
HSJS3_k127_6740563_3	1288484.APCS01000057_gene2859	2.679e-168	552.0	COG0475@1|root,COG1226@1|root,COG5207@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,COG5207@2|Bacteria,1WJ1X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
HSJS3_k127_6740563_4	215803.DB30_7235	8.271e-119	418.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	1224|Proteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_6740563_13	365528.KB891256_gene5491	5.765e-09	64.0	COG1695@1|root,COG1695@2|Bacteria,2IQ70@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator padr family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_6740563_10	234267.Acid_1052	2.84e-22	100.0	COG1695@1|root,COG1695@2|Bacteria,3Y5ZC@57723|Acidobacteria	57723|Acidobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_6740563_1	1278073.MYSTI_07864	1.774e-196	644.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_6740563_8	861299.J421_2173	1.1e-51	194.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_2173|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6740563_12	870187.Thini_3841	3.604e-19	94.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6780280_12	479434.Sthe_1613	3.838e-28	119.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi,27Z70@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HSJS3_k127_6780280_4	1379270.AUXF01000004_gene3227	3.848e-103	359.0	COG1432@1|root,COG1432@2|Bacteria,1ZSRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
HSJS3_k127_6780280_3	861299.J421_2604	4.071e-128	436.0	COG0318@1|root,COG0318@2|Bacteria,1ZSXP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HSJS3_k127_6780280_6	861299.J421_2532	1.742e-90	318.0	COG0337@1|root,COG0337@2|Bacteria,1ZSS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HSJS3_k127_6780280_11	379066.GAU_2350	6.758e-37	157.0	COG2856@1|root,COG2856@2|Bacteria,1ZSXU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6780280_1	861299.J421_2591	2.096e-169	557.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HSJS3_k127_6780280_2	861299.J421_2719	6.462e-136	446.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HSJS3_k127_6780280_15	671143.DAMO_0014	5.984e-06	53.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
HSJS3_k127_6780280_16	33035.JPJF01000049_gene581	0.0005593	49.0	COG1719@1|root,COG1719@2|Bacteria,1V370@1239|Firmicutes,25DJT@186801|Clostridia	186801|Clostridia	S	V4R	-	-	-	-	-	-	-	-	-	-	-	-	V4R
HSJS3_k127_6780280_13	237368.SCABRO_01685	5.226e-26	113.0	COG0816@1|root,COG0816@2|Bacteria,2J0EV@203682|Planctomycetes	203682|Planctomycetes	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HSJS3_k127_6780280_8	861299.J421_2620	2.599e-65	241.0	COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HSJS3_k127_6780280_10	479434.Sthe_1494	1.208e-46	180.0	COG0352@1|root,COG0352@2|Bacteria,2G6P0@200795|Chloroflexi,27Y70@189775|Thermomicrobia	189775|Thermomicrobia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
HSJS3_k127_6780280_9	429009.Adeg_1471	3.824e-56	205.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,42GGH@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
HSJS3_k127_6780280_14	379066.GAU_0717	2.48e-13	75.0	COG0355@1|root,COG0355@2|Bacteria,1ZU1K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
HSJS3_k127_6780280_0	768670.Calni_1587	2.725e-219	697.0	COG0055@1|root,COG0055@2|Bacteria,2GEQN@200930|Deferribacteres	200930|Deferribacteres	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HSJS3_k127_6780280_5	861299.J421_2628	2.086e-101	339.0	COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HSJS3_k127_6780280_7	1449126.JQKL01000005_gene873	1.07e-84	285.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,2684Y@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HSJS3_k127_6805584_7	1189612.A33Q_1758	2.485e-37	149.0	COG0624@1|root,COG0624@2|Bacteria,4NJN0@976|Bacteroidetes,47MGJ@768503|Cytophagia	976|Bacteroidetes	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HSJS3_k127_6805584_5	861299.J421_3492	1.391e-43	173.0	COG3765@1|root,COG3765@2|Bacteria,1ZV56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6805584_0	1379270.AUXF01000003_gene3703	1.446e-249	785.0	COG1217@1|root,COG1217@2|Bacteria,1ZT8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
HSJS3_k127_6805584_4	690850.Desaf_2356	2.152e-48	192.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,42SZH@68525|delta/epsilon subdivisions,2WPX7@28221|Deltaproteobacteria,2M9RM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
HSJS3_k127_6805584_8	1121931.AUHG01000010_gene495	2.538e-23	106.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia	976|Bacteroidetes	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HSJS3_k127_6805584_3	861299.J421_1678	5.42e-106	355.0	COG0075@1|root,COG0075@2|Bacteria,1ZTF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_6805584_1	1191523.MROS_2848	9.498e-155	503.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
HSJS3_k127_6805584_2	448385.sce5442	2.415e-139	456.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,42YEF@68525|delta/epsilon subdivisions,2WU92@28221|Deltaproteobacteria,2YYRX@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
HSJS3_k127_6805584_6	1210884.HG799467_gene13462	1.756e-37	146.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
HSJS3_k127_6818853_5	1232410.KI421426_gene1373	1.313e-167	547.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,43U78@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
HSJS3_k127_6818853_3	1448860.BBJO01000009_gene842	8.329e-179	583.0	COG0272@1|root,arCOG04754@2157|Archaea,2XTQT@28890|Euryarchaeota,23S29@183963|Halobacteria	183963|Halobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HSJS3_k127_6818853_10	479433.Caci_8801	2.413e-123	436.0	COG0520@1|root,COG0520@2|Bacteria,2H9MG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_6818853_33	324057.Pjdr2_1702	2.132e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,1V94Z@1239|Firmicutes,4HJG5@91061|Bacilli,26XHJ@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_6818853_41	398527.Bphyt_1667	0.0007487	49.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VP8R@28216|Betaproteobacteria,1K201@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
HSJS3_k127_6818853_37	1379270.AUXF01000004_gene3112	3.033e-17	92.0	COG2207@1|root,COG3749@1|root,COG2207@2|Bacteria,COG3749@2|Bacteria,1ZUCG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HSJS3_k127_6818853_20	1254432.SCE1572_34120	1.081e-81	307.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,43823@68525|delta/epsilon subdivisions,2X3C5@28221|Deltaproteobacteria,2YVD0@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HSJS3_k127_6818853_9	1158756.AQXQ01000008_gene2388	3.227e-129	420.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,1SM99@1236|Gammaproteobacteria,1X016@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6818853_23	1265502.KB905946_gene1118	2.903e-71	253.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VR34@28216|Betaproteobacteria,4AA2R@80864|Comamonadaceae	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HSJS3_k127_6818853_12	1089546.AQUI01000002_gene2068	6.099e-114	383.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,409RH@622450|Actinopolysporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
HSJS3_k127_6818853_21	869210.Marky_1929	5.165e-79	274.0	COG0247@1|root,COG0247@2|Bacteria,1WIZV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
HSJS3_k127_6818853_4	526227.Mesil_1095	1.945e-176	571.0	COG1139@1|root,COG1139@2|Bacteria,1WITJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	protein containing a ferredoxin-like domain	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
HSJS3_k127_6818853_27	869210.Marky_1932	2.064e-55	199.0	COG1556@1|root,COG1556@2|Bacteria,1WJRT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
HSJS3_k127_6818853_28	644282.Deba_1638	1.872e-52	203.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42MGQ@68525|delta/epsilon subdivisions,2WJ87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	COGs COG0531 Amino acid transporter	-	-	-	ko:K03294,ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.2,2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
HSJS3_k127_6818853_26	1122132.AQYH01000002_gene1245	8.446e-65	248.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2TT5I@28211|Alphaproteobacteria,4BCWB@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
HSJS3_k127_6818853_22	861299.J421_0510	2.196e-77	273.0	COG2220@1|root,COG2220@2|Bacteria,1ZUY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HSJS3_k127_6818853_31	1123252.ATZF01000002_gene2431	3.047e-33	135.0	COG1309@1|root,COG1309@2|Bacteria,1V71B@1239|Firmicutes,4HJ9J@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	tetR1	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HSJS3_k127_6818853_2	1250232.JQNJ01000001_gene3006	2.391e-214	679.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HSJS3_k127_6818853_15	204669.Acid345_0985	2.86e-107	364.0	COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria,2JKGK@204432|Acidobacteriia	204432|Acidobacteriia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HSJS3_k127_6818853_16	247633.GP2143_03848	1.434e-101	346.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria,1J7Y5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	nylB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS3_k127_6818853_19	240016.ABIZ01000001_gene997	7.58e-93	312.0	COG0396@1|root,COG0396@2|Bacteria,46SGE@74201|Verrucomicrobia,2ITY7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HSJS3_k127_6818853_1	745776.DGo_CA2472	2.146e-224	703.0	COG0719@1|root,COG0719@2|Bacteria,1WIDC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
HSJS3_k127_6818853_14	309801.trd_0379	1.082e-108	368.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HSJS3_k127_6818853_36	575540.Isop_3231	2.699e-19	93.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
HSJS3_k127_6818853_6	765420.OSCT_1487	2.884e-158	510.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,3766K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
HSJS3_k127_6818853_29	1121085.AUCI01000006_gene1494	3.511e-36	154.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,1ZFQ8@1386|Bacillus	91061|Bacilli	C	COG0822 NifU homolog involved in Fe-S cluster formation	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HSJS3_k127_6818853_30	1117108.PAALTS15_19618	3.447e-34	139.0	COG0350@1|root,COG1600@1|root,COG0350@2|Bacteria,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,26R4Y@186822|Paenibacillaceae	91061|Bacilli	C	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
HSJS3_k127_6818853_13	935863.AWZR01000005_gene2169	3.897e-109	364.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1XC3M@135614|Xanthomonadales	135614|Xanthomonadales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS3_k127_6818853_24	1131451.O1K_20392	2.947e-70	256.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1X3PM@135614|Xanthomonadales	135614|Xanthomonadales	E	acid dehydrogenase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
HSJS3_k127_6818853_17	644966.Tmar_0616	1.31e-94	324.0	COG1063@1|root,COG1063@2|Bacteria,1UY29@1239|Firmicutes,24C7S@186801|Clostridia	186801|Clostridia	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_6818853_40	1499967.BAYZ01000036_gene2434	0.0004005	51.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
HSJS3_k127_6818853_7	1452718.JBOY01000048_gene1091	2.545e-139	456.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NAD FAD-binding protein	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
HSJS3_k127_6818853_18	887062.HGR_05454	5.525e-93	314.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
HSJS3_k127_6818853_8	1384056.N787_09915	2.757e-133	445.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1X2ZB@135614|Xanthomonadales	135614|Xanthomonadales	M	synthase	cfaA	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
HSJS3_k127_6818853_11	1500890.JQNL01000001_gene3702	5.72e-119	394.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1X38D@135614|Xanthomonadales	135614|Xanthomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
HSJS3_k127_6818853_32	384765.SIAM614_26603	3.726e-30	129.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
HSJS3_k127_6818853_35	469383.Cwoe_3568	1.159e-21	107.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria,4CTK9@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
HSJS3_k127_6818853_25	926556.Echvi_1259	8.851e-66	230.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PZ4@768503|Cytophagia	976|Bacteroidetes	O	peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HSJS3_k127_6818853_38	1179778.PMM47T1_24209	9.681e-12	74.0	COG1309@1|root,COG1309@2|Bacteria,1RCI9@1224|Proteobacteria,1S3KX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HSJS3_k127_6818853_0	234267.Acid_4902	4.853e-242	784.0	COG5549@1|root,COG5549@2|Bacteria,3Y2IY@57723|Acidobacteria	57723|Acidobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HSJS3_k127_6818853_34	1229909.NSED_06605	4.976e-22	107.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	ko:K21990	-	-	-	-	ko00000	1.A.16.4	-	-	Form_Nir_trans,Thioredoxin_4
HSJS3_k127_6819459_0	502025.Hoch_4261	5.282e-178	570.0	COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria	1224|Proteobacteria	S	C4-dicarboxylate anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
HSJS3_k127_6871418_4	1121405.dsmv_0318	1.586e-112	374.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2MHY9@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
HSJS3_k127_6871418_0	861299.J421_2423	0.0	1092.0	COG0495@1|root,COG0495@2|Bacteria,1ZSXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HSJS3_k127_6871418_1	866536.Belba_2633	1.997e-222	704.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47MDS@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran,Peptidase_C39
HSJS3_k127_6871418_11	1123024.AUII01000010_gene681	4.234e-64	226.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
HSJS3_k127_6871418_9	1379270.AUXF01000004_gene3140	3.519e-72	259.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
HSJS3_k127_6871418_6	861299.J421_2641	1.859e-93	332.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
HSJS3_k127_6871418_18	518766.Rmar_1680	3.783e-22	101.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HSJS3_k127_6871418_7	292459.STH1268	3.023e-84	301.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
HSJS3_k127_6871418_3	861299.J421_2359	5.982e-155	525.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_2359|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6871418_17	234267.Acid_5730	1.431e-26	112.0	COG1695@1|root,COG1695@2|Bacteria,3Y5BK@57723|Acidobacteria	57723|Acidobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_6871418_2	1379270.AUXF01000003_gene3673	3.7e-183	590.0	COG1132@1|root,COG1132@2|Bacteria,1ZSZC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HSJS3_k127_6871418_10	42256.RradSPS_2739	8.768e-68	240.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,4CPXC@84995|Rubrobacteria	84995|Rubrobacteria	K	TipAS antibiotic-recognition domain	-	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TipAS
HSJS3_k127_6871418_13	1379270.AUXF01000006_gene150	4.655e-51	188.0	2DEWU@1|root,2ZPJP@2|Bacteria,1ZUFA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6871418_8	102129.Lepto7375DRAFT_2070	3.46e-78	276.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria,1H7VM@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
HSJS3_k127_6871418_21	1335757.SPICUR_04885	1.306e-05	51.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1X2FV@135613|Chromatiales	135613|Chromatiales	S	Smr protein	-	-	-	-	-	-	-	-	-	-	-	-	Smr
HSJS3_k127_6871418_12	204669.Acid345_1150	2.459e-54	199.0	arCOG09454@1|root,31B41@2|Bacteria,3Y8HD@57723|Acidobacteria,2JNG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6871418_20	1206732.BAGD01000097_gene4156	1.356e-09	59.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4G2TT@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HSJS3_k127_6871418_16	2074.JNYD01000019_gene2458	2.013e-31	130.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4E57U@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HSJS3_k127_6871418_15	452637.Oter_1329	9.3e-34	138.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HSJS3_k127_6871418_19	1123508.JH636442_gene3962	3.004e-17	89.0	COG0745@1|root,COG0745@2|Bacteria,2J0GS@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Response_reg
HSJS3_k127_6871418_14	195250.CM001776_gene2964	7.125e-40	155.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1H0K1@1129|Synechococcus	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
HSJS3_k127_6871418_5	935948.KE386494_gene944	1.556e-105	357.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HSJS3_k127_6890790_0	269800.Tfu_2024	1.146e-301	944.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EH1A@85012|Streptosporangiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HSJS3_k127_6891025_5	378806.STAUR_2943	7.634e-45	174.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria,2YYUS@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HSJS3_k127_6891025_7	1379270.AUXF01000002_gene1849	1.052e-36	146.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_6891025_8	383372.Rcas_0300	4.612e-11	75.0	COG0720@1|root,COG0720@2|Bacteria,2G992@200795|Chloroflexi,3753G@32061|Chloroflexia	32061|Chloroflexia	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HSJS3_k127_6891025_4	1379270.AUXF01000004_gene3235	1.085e-76	263.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
HSJS3_k127_6891025_1	861299.J421_2825	4.174e-246	786.0	COG1198@1|root,COG1198@2|Bacteria,1ZTE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
HSJS3_k127_6891025_2	379066.GAU_2584	1.096e-109	371.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
HSJS3_k127_6891025_6	861299.J421_2820	1.716e-37	154.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MetW,Methyltransf_11,Methyltransf_20,Methyltransf_23,Methyltransf_25,Methyltransf_31
HSJS3_k127_6891025_9	671143.DAMO_1586	7.237e-08	64.0	COG3088@1|root,COG3088@2|Bacteria,2NRBD@2323|unclassified Bacteria	2|Bacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02198,ko:K02200	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmH
HSJS3_k127_6891025_3	290397.Adeh_3438	3.723e-85	294.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
HSJS3_k127_6891025_0	861299.J421_3571	0.0	1443.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HSJS3_k127_6974949_0	1379698.RBG1_1C00001G0312	2.206e-123	399.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HSJS3_k127_6974949_2	861299.J421_2712	1.007e-41	159.0	COG2236@1|root,COG2236@2|Bacteria,1ZTQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
HSJS3_k127_6974949_1	882.DVU_1942	3.482e-99	346.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,42U2G@68525|delta/epsilon subdivisions,2WQBG@28221|Deltaproteobacteria,2M8TG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Dihydroxyacetone kinase family	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
HSJS3_k127_6974949_3	700598.Niako_6385	1.737e-35	136.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HSJS3_k127_6982182_0	861299.J421_0666	1.562e-169	539.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6982182_4	1122138.AQUZ01000078_gene6139	2.139e-17	86.0	COG1977@1|root,COG1977@2|Bacteria,2GQM9@201174|Actinobacteria,4DW7X@85009|Propionibacteriales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HSJS3_k127_6982182_3	1044.EH31_01500	1.674e-17	96.0	COG3595@1|root,COG3595@2|Bacteria,1QUNK@1224|Proteobacteria,2TW1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6982182_1	644966.Tmar_2240	4.198e-146	479.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WCEJ@538999|Clostridiales incertae sedis	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HSJS3_k127_6982182_6	1210884.HG799462_gene8760	0.0001838	52.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
HSJS3_k127_6982182_2	861299.J421_0916	2.461e-132	435.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_6982182_5	644282.Deba_0427	3.141e-12	80.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_7009860_4	861299.J421_0308	6.998e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_7009860_1	234267.Acid_4169	1.855e-145	475.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HSJS3_k127_7009860_0	926566.Terro_2393	7.19e-169	552.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HSJS3_k127_7009860_2	234267.Acid_6478	1.065e-97	323.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HSJS3_k127_7009860_3	1267533.KB906736_gene1139	3.889e-57	201.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_7042263_5	1379270.AUXF01000002_gene1586	5.09e-153	516.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1586|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7042263_3	1121939.L861_10115	1.888e-164	528.0	COG0075@1|root,COG0075@2|Bacteria,1QCKV@1224|Proteobacteria,1RQ1T@1236|Gammaproteobacteria,1XIT4@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_7042263_10	869210.Marky_1251	5.729e-127	417.0	COG0665@1|root,COG0665@2|Bacteria,1WIHS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
HSJS3_k127_7042263_31	1122975.AQVC01000064_gene82	0.0007138	53.0	2BZQ4@1|root,32TE6@2|Bacteria,4NTHT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7042263_11	1479238.JQMZ01000001_gene442	3e-118	402.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,43WJ0@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HSJS3_k127_7042263_29	84531.JMTZ01000056_gene2553	1.186e-16	91.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,1S914@1236|Gammaproteobacteria,1XC1N@135614|Xanthomonadales	135614|Xanthomonadales	KT	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,Polyketide_cyc2
HSJS3_k127_7042263_21	861299.J421_3686	5.599e-54	209.0	COG2755@1|root,COG2755@2|Bacteria,1ZTN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GDSL-like Lipase/Acylhydrolase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
HSJS3_k127_7042263_17	1122603.ATVI01000006_gene572	8.925e-78	268.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X623@135614|Xanthomonadales	135614|Xanthomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_7042263_2	309807.SRU_0696	6.19e-165	549.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1FIZR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_7042263_8	861299.J421_2577	4.423e-137	451.0	COG0436@1|root,COG0436@2|Bacteria,1ZT26@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_7042263_23	66869.JNXG01000003_gene3107	1.134e-46	185.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria,41BY1@629295|Streptomyces griseus group	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
HSJS3_k127_7042263_13	861299.J421_0488	3.06e-107	375.0	COG2223@1|root,COG2223@2|Bacteria,1ZT8I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS3_k127_7042263_30	1458427.BAWN01000028_gene1642	3.061e-11	69.0	COG2372@1|root,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	copC	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
HSJS3_k127_7042263_28	479434.Sthe_3292	1.17e-19	100.0	COG1276@1|root,COG2372@1|root,COG2834@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,COG2834@2|Bacteria,2G8KM@200795|Chloroflexi,27XZB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
HSJS3_k127_7042263_14	1265313.HRUBRA_02839	2.047e-103	366.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RPSP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycine betaine	opuCC	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
HSJS3_k127_7042263_20	645465.ACUR01000525_gene2383	1.953e-65	233.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	opuCA	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
HSJS3_k127_7042263_19	1906.SFRA_05205	7.655e-71	251.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
HSJS3_k127_7042263_15	397945.Aave_1144	5.94e-93	310.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,4AAK0@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
HSJS3_k127_7042263_26	443143.GM18_4390	2.045e-28	130.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42W9X@68525|delta/epsilon subdivisions,2WSEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA-1	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HSJS3_k127_7042263_18	1379270.AUXF01000006_gene230	2.258e-76	263.0	COG0377@1|root,COG0377@2|Bacteria,1ZT85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HSJS3_k127_7042263_24	861299.J421_3293	2.582e-39	158.0	COG0852@1|root,COG0852@2|Bacteria,1ZTCJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HSJS3_k127_7042263_1	861299.J421_3292	1.223e-176	562.0	COG0649@1|root,COG0649@2|Bacteria,1ZSV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
HSJS3_k127_7042263_22	1379270.AUXF01000006_gene233	2.12e-52	195.0	COG1905@1|root,COG1905@2|Bacteria,1ZTJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HSJS3_k127_7042263_6	765869.BDW_11310	6.407e-147	482.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2MTQY@213481|Bdellovibrionales,2WJ1W@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
HSJS3_k127_7042263_7	861299.J421_3289	4.803e-143	471.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1ZTDW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
HSJS3_k127_7042263_9	861299.J421_3288	2.329e-128	422.0	COG1005@1|root,COG1005@2|Bacteria,1ZTDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HSJS3_k127_7042263_16	1379270.AUXF01000006_gene237	3.778e-79	267.0	COG1143@1|root,COG1143@2|Bacteria,1ZTHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
HSJS3_k127_7042263_27	247490.KSU1_D0319	1.111e-25	117.0	COG0839@1|root,COG0839@2|Bacteria,2J0MC@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HSJS3_k127_7042263_25	1379270.AUXF01000006_gene239	8.914e-31	125.0	COG0713@1|root,COG0713@2|Bacteria,1ZU00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HSJS3_k127_7042263_0	861299.J421_3284	4.777e-205	660.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
HSJS3_k127_7042263_4	1379698.RBG1_1C00001G1061	2.889e-155	502.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HSJS3_k127_7042263_12	398767.Glov_3125	1.185e-112	378.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HSJS3_k127_7073530_0	861299.J421_2656	9.718e-300	943.0	COG0587@1|root,COG0587@2|Bacteria,1ZT8N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
HSJS3_k127_7073530_1	525904.Tter_2300	0.0004873	46.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
HSJS3_k127_7116036_2	1182590.BN5_03290	2.219e-68	243.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1YDFT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HSJS3_k127_7116036_0	1379270.AUXF01000001_gene2028	9.588e-119	389.0	COG0623@1|root,COG0623@2|Bacteria,1ZTGW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS3_k127_7116036_1	1123070.KB899254_gene1284	7.407e-99	342.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
HSJS3_k127_7116036_3	215803.DB30_7195	1.019e-19	101.0	COG1075@1|root,COG1075@2|Bacteria,1Q8HV@1224|Proteobacteria,439QR@68525|delta/epsilon subdivisions,2X539@28221|Deltaproteobacteria,2Z01W@29|Myxococcales	28221|Deltaproteobacteria	S	Lipase (class 2)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2
HSJS3_k127_7230921_0	518766.Rmar_0491	1.173e-100	335.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJX9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HSJS3_k127_7230921_1	1267535.KB906767_gene4657	5.472e-96	327.0	COG3852@1|root,COG3852@2|Bacteria,3Y3JR@57723|Acidobacteria,2JIY1@204432|Acidobacteriia	204432|Acidobacteriia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
HSJS3_k127_726725_2	379066.GAU_3104	2.461e-05	49.0	COG1196@1|root,COG1196@2|Bacteria,1ZU8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_726725_1	1210884.HG799463_gene9356	2.563e-33	136.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,2J2QP@203682|Planctomycetes	203682|Planctomycetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Reg_prop,Y_Y_Y
HSJS3_k127_726725_0	502025.Hoch_5309	6.384e-141	463.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
HSJS3_k127_7365942_1	746697.Aeqsu_0161	1.056e-30	133.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1HZGV@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
HSJS3_k127_7365942_0	309807.SRU_1980	4.979e-174	563.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1FJYD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HSJS3_k127_7366954_17	1379270.AUXF01000003_gene3516	2.844e-13	74.0	COG0740@1|root,COG0740@2|Bacteria,1ZSPR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HSJS3_k127_7366954_5	861299.J421_3854	4.648e-86	300.0	COG0544@1|root,COG0544@2|Bacteria,1ZSSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
HSJS3_k127_7366954_3	861299.J421_3849	3.14e-96	333.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_7366954_0	56780.SYN_01983	1.08e-263	827.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MR7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HSJS3_k127_7366954_9	215803.DB30_3898	2.78e-64	228.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HSJS3_k127_7366954_7	562970.Btus_1326	2.376e-73	263.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,277XQ@186823|Alicyclobacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HSJS3_k127_7366954_6	1122962.AULH01000007_gene1881	9.747e-78	270.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,36Y2Q@31993|Methylocystaceae	28211|Alphaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HSJS3_k127_7366954_13	1121428.DESHY_110209___1	1.029e-41	164.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,261RV@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HSJS3_k127_7366954_10	379066.GAU_2351	7.178e-54	199.0	COG1989@1|root,COG1989@2|Bacteria,1ZT9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HSJS3_k127_7366954_4	497964.CfE428DRAFT_1013	4.29e-87	299.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HSJS3_k127_7366954_12	266117.Rxyl_1750	7.747e-47	175.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4CTCP@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HSJS3_k127_7366954_11	373903.Hore_12560	1.865e-53	205.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HSJS3_k127_7366954_1	379066.GAU_2494	1.562e-131	430.0	COG0714@1|root,COG0714@2|Bacteria,1ZT5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS3_k127_7366954_8	379066.GAU_2490	8.405e-66	241.0	COG0356@1|root,COG0356@2|Bacteria,1ZSQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HSJS3_k127_7366954_16	861299.J421_3946	1.001e-16	82.0	COG0636@1|root,COG0636@2|Bacteria,1ZU1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HSJS3_k127_7366954_15	290315.Clim_2489	4.686e-27	123.0	COG0711@1|root,COG0711@2|Bacteria,1FDW3@1090|Chlorobi	1090|Chlorobi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HSJS3_k127_7366954_14	1379270.AUXF01000003_gene3430	3.437e-35	141.0	COG0712@1|root,COG0712@2|Bacteria,1ZTP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HSJS3_k127_7366954_2	986075.CathTA2_2809	4.708e-125	407.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HSJS3_k127_749440_13	1379270.AUXF01000005_gene399	2.51e-75	261.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HSJS3_k127_749440_7	379066.GAU_1124	4.54e-120	397.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HSJS3_k127_749440_28	379066.GAU_1123	9.492e-28	122.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HSJS3_k127_749440_9	379066.GAU_1122	1.59e-91	322.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HSJS3_k127_749440_24	1379270.AUXF01000005_gene391	8.022e-41	165.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HSJS3_k127_749440_10	861299.J421_2886	2.269e-89	298.0	COG1100@1|root,COG1100@2|Bacteria,1ZSQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
HSJS3_k127_749440_14	1379270.AUXF01000005_gene387	4.531e-72	248.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HSJS3_k127_749440_30	1232410.KI421424_gene1852	1.19e-22	106.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,43SPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	YbaB/EbfC DNA-binding family	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
HSJS3_k127_749440_6	861299.J421_2881	8.883e-132	440.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HSJS3_k127_749440_34	1273125.Rrhod_2637	3.598e-18	89.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4G1R8@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HSJS3_k127_749440_4	379066.GAU_1191	5.743e-138	458.0	COG2876@1|root,COG2876@2|Bacteria,1ZTB0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
HSJS3_k127_749440_21	1379270.AUXF01000005_gene503	2.428e-45	174.0	COG1234@1|root,COG1234@2|Bacteria,1ZT5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HSJS3_k127_749440_1	861299.J421_2945	3.429e-207	690.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HSJS3_k127_749440_37	1173027.Mic7113_6231	0.0008004	51.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1G0TN@1117|Cyanobacteria,1H8RU@1150|Oscillatoriales	1117|Cyanobacteria	D	exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
HSJS3_k127_749440_27	290315.Clim_0102	3.996e-31	132.0	COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi	1090|Chlorobi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HSJS3_k127_749440_26	891968.Anamo_0374	1.274e-31	130.0	COG0359@1|root,COG0359@2|Bacteria,3TB7W@508458|Synergistetes	508458|Synergistetes	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HSJS3_k127_749440_32	861299.J421_2951	2.74e-20	104.0	2F1RZ@1|root,33US3@2|Bacteria,1ZUSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
HSJS3_k127_749440_36	1565129.JSFF01000037_gene3003	3.39e-12	78.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,2QCHQ@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HSJS3_k127_749440_33	555079.Toce_2257	4.476e-19	99.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,42GZP@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HSJS3_k127_749440_29	565045.NOR51B_630	3.043e-27	115.0	2FG7R@1|root,34844@2|Bacteria,1P1QM@1224|Proteobacteria,1SRGS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_749440_31	472759.Nhal_1569	1.023e-21	108.0	COG4850@1|root,COG4850@2|Bacteria,1R3ST@1224|Proteobacteria,1RYC6@1236|Gammaproteobacteria,1WZHP@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
HSJS3_k127_749440_12	1255043.TVNIR_0316	2.499e-80	282.0	COG1018@1|root,COG1018@2|Bacteria,1R5YD@1224|Proteobacteria,1T2RI@1236|Gammaproteobacteria,1WY0W@135613|Chromatiales	135613|Chromatiales	C	PFAM Oxidoreductase FAD NAD(P)-binding	-	-	1.6.2.2	ko:K00326	ko00520,map00520	-	R00100	-	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
HSJS3_k127_749440_15	935948.KE386494_gene460	2.456e-68	247.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,42FC4@68295|Thermoanaerobacterales	186801|Clostridia	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
HSJS3_k127_749440_0	522772.Dacet_0072	5.263e-245	775.0	COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres	200930|Deferribacteres	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
HSJS3_k127_749440_16	1379270.AUXF01000005_gene524	6.334e-60	213.0	COG0193@1|root,COG0193@2|Bacteria,1ZTKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HSJS3_k127_749440_23	1379270.AUXF01000005_gene525	7.86e-42	162.0	COG1825@1|root,COG1825@2|Bacteria,1ZTHZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HSJS3_k127_749440_5	1379270.AUXF01000005_gene526	3.72e-135	443.0	COG0462@1|root,COG0462@2|Bacteria,1ZT7Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HSJS3_k127_749440_18	861299.J421_0491	4.219e-55	216.0	2EZKR@1|root,33SRW@2|Bacteria,1ZSQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_749440_22	604331.AUHY01000015_gene2669	7.769e-43	179.0	COG1947@1|root,COG1947@2|Bacteria,1WJXM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HSJS3_k127_749440_19	861299.J421_2969	8.499e-54	203.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HSJS3_k127_749440_11	13035.Dacsa_2686	2.376e-82	286.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
HSJS3_k127_749440_35	1121428.DESHY_40225___1	8.958e-14	82.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,261DG@186807|Peptococcaceae	186801|Clostridia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HSJS3_k127_749440_3	861299.J421_3506	3.189e-142	464.0	COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HSJS3_k127_749440_2	861299.J421_3508	1.324e-164	531.0	COG2256@1|root,COG2256@2|Bacteria,1ZTCA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
HSJS3_k127_749440_8	861299.J421_3513	1.129e-92	323.0	COG0617@1|root,COG0617@2|Bacteria,1ZSKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HSJS3_k127_749440_17	861299.J421_3519	1.579e-55	202.0	COG0279@1|root,COG0279@2|Bacteria,1ZTY5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
HSJS3_k127_749440_25	861299.J421_3520	7.478e-35	143.0	COG4464@1|root,COG4464@2|Bacteria,1ZTQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HSJS3_k127_749440_20	379066.GAU_1915	1.2e-48	182.0	COG0013@1|root,COG0013@2|Bacteria,1ZT18@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HSJS3_k127_7667167_9	335543.Sfum_0899	3.13e-79	272.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2MRD0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
HSJS3_k127_7667167_24	1121104.AQXH01000001_gene2164	2.399e-05	50.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
HSJS3_k127_7667167_17	946483.Cenrod_2260	1.381e-33	148.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS3_k127_7667167_13	861299.J421_0860	1.499e-66	233.0	COG2353@1|root,COG2353@2|Bacteria,1ZV1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HSJS3_k127_7667167_7	204669.Acid345_3014	2.258e-82	303.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HSJS3_k127_7667167_20	861299.J421_4538	3.866e-27	124.0	2C9AW@1|root,2ZVNX@2|Bacteria,1ZUAK@142182|Gemmatimonadetes	861299.J421_4538|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7667167_23	861299.J421_4539	2.174e-10	72.0	28YSJ@1|root,2ZKJZ@2|Bacteria,1ZU1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7667167_21	861299.J421_4540	4.267e-21	103.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
HSJS3_k127_7667167_16	861299.J421_4541	1.159e-33	138.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HSJS3_k127_7667167_22	1121875.KB907548_gene1518	3.3e-20	103.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HSJS3_k127_7667167_19	1385935.N836_35030	3.791e-29	123.0	2DMJE@1|root,32RYR@2|Bacteria,1G6SI@1117|Cyanobacteria,1HBXF@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
HSJS3_k127_7667167_18	215803.DB30_7236	2.433e-30	124.0	COG1695@1|root,COG1695@2|Bacteria,1PMEN@1224|Proteobacteria,43544@68525|delta/epsilon subdivisions,2WZF7@28221|Deltaproteobacteria,2Z209@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_7667167_1	861299.J421_2535	8.291e-162	542.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_7667167_10	1040987.AZUY01000001_gene2594	1.174e-78	297.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TUAM@28211|Alphaproteobacteria,43PW5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS3_k127_7667167_3	861299.J421_1395	3.598e-126	437.0	COG2234@1|root,COG2234@2|Bacteria,1ZSXY@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HSJS3_k127_7667167_14	986075.CathTA2_1906	6.123e-60	219.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli	91061|Bacilli	M	Sortase and related acyltransferases	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
HSJS3_k127_7667167_26	262724.TT_C0492	0.0003556	52.0	COG1266@1|root,COG1266@2|Bacteria,1WK1W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HSJS3_k127_7667167_11	379066.GAU_0494	1.263e-76	284.0	COG4206@1|root,COG4206@2|Bacteria,1ZV6P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
HSJS3_k127_7667167_15	379066.GAU_0493	8.884e-35	154.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7667167_5	1121930.AQXG01000016_gene1813	7.592e-102	341.0	COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,1IYJY@117747|Sphingobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
HSJS3_k127_7667167_2	1340493.JNIF01000003_gene3440	4.668e-161	540.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,Laminin_G_3
HSJS3_k127_7667167_25	1125701.HMPREF1221_00533	0.0002931	54.0	COG0457@1|root,COG3391@1|root,COG0457@2|Bacteria,COG3391@2|Bacteria,2J5QG@203691|Spirochaetes	203691|Spirochaetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
HSJS3_k127_7667167_12	1304880.JAGB01000002_gene1591	2.922e-67	237.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia	186801|Clostridia	T	domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
HSJS3_k127_7667167_0	941449.dsx2_1144	4.602e-163	539.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2MB2B@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
HSJS3_k127_7667167_6	472759.Nhal_1587	4.47e-87	296.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,1RZBF@1236|Gammaproteobacteria,1X0F6@135613|Chromatiales	135613|Chromatiales	Q	PFAM isochorismatase hydrolase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
HSJS3_k127_7667167_8	595460.RRSWK_05281	7.085e-80	279.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
HSJS3_k127_7667167_4	1379270.AUXF01000001_gene2140	4.048e-108	362.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
HSJS3_k127_7678745_1	1121930.AQXG01000002_gene2074	1.01e-41	158.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IQ09@117747|Sphingobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_7678745_0	1122218.KB893665_gene182	3.885e-271	854.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,1JTJS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Vitamin B12 dependent methionine synthase activation	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HSJS3_k127_7690196_2	309800.C498_05446	2.138e-47	181.0	COG3845@1|root,arCOG00186@2157|Archaea,2XUEG@28890|Euryarchaeota,23S1J@183963|Halobacteria	183963|Halobacteria	E	transport systems, ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HSJS3_k127_7690196_0	861299.J421_1178	4.915e-86	298.0	COG4603@1|root,COG4603@2|Bacteria,1ZTGR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HSJS3_k127_7690196_1	861299.J421_1179	4.3e-80	291.0	COG1079@1|root,COG1079@2|Bacteria,1ZSUD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HSJS3_k127_7739556_4	1297742.A176_01972	4.69e-32	133.0	COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria	1224|Proteobacteria	E	Xaa-Pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
HSJS3_k127_7739556_7	1089547.KB913013_gene857	1.549e-08	64.0	28N6F@1|root,2ZBBB@2|Bacteria,4NGM1@976|Bacteroidetes,47P0U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7739556_5	1479237.JMLY01000001_gene1882	1.046e-10	63.0	28N6F@1|root,2ZBBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7739556_2	1304875.JAFZ01000003_gene580	7.299e-56	215.0	COG1115@1|root,COG1115@2|Bacteria,3TAMW@508458|Synergistetes	508458|Synergistetes	E	TIGRFAM amino acid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
HSJS3_k127_7739556_3	1507.HMPREF0262_01151	4.884e-39	153.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HSJS3_k127_7739556_6	446462.Amir_4170	1.738e-09	70.0	COG4126@1|root,COG4126@2|Bacteria,2ICBM@201174|Actinobacteria,4E5X1@85010|Pseudonocardiales	201174|Actinobacteria	E	AroM protein	-	-	-	ko:K14591	-	-	-	-	ko00000	-	-	-	AroM
HSJS3_k127_7739556_0	1120973.AQXL01000085_gene2898	3.257e-119	397.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4HBNG@91061|Bacilli	91061|Bacilli	F	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring	-	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HSJS3_k127_7739556_1	887062.HGR_00400	1.629e-71	250.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2VMFS@28216|Betaproteobacteria,4AES4@80864|Comamonadaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HSJS3_k127_7765308_1	1192034.CAP_4888	2.144e-218	698.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HSJS3_k127_7765308_9	502025.Hoch_4148	6.594e-111	375.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2WJZA@28221|Deltaproteobacteria,2YZ8X@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HSJS3_k127_7765308_13	861299.J421_1168	1.246e-85	295.0	COG1744@1|root,COG1744@2|Bacteria,1ZSMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HSJS3_k127_7765308_10	446470.Snas_1353	5.481e-105	359.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4EXVX@85014|Glycomycetales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HSJS3_k127_7765308_12	861299.J421_1178	2.32e-86	306.0	COG4603@1|root,COG4603@2|Bacteria,1ZTGR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HSJS3_k127_7765308_11	861299.J421_1179	2.802e-93	320.0	COG1079@1|root,COG1079@2|Bacteria,1ZSUD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HSJS3_k127_7765308_4	926549.KI421517_gene2980	7.392e-137	472.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia	976|Bacteroidetes	G	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HSJS3_k127_7765308_0	861299.J421_1758	1.853e-235	743.0	COG0591@1|root,COG0591@2|Bacteria,1ZT93@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HSJS3_k127_7765308_5	439235.Dalk_1022	1.449e-131	428.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HSJS3_k127_7765308_2	1123389.ATXJ01000002_gene1468	4.663e-193	612.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
HSJS3_k127_7765308_14	765911.Thivi_0252	1.425e-74	259.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1WXW3@135613|Chromatiales	135613|Chromatiales	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
HSJS3_k127_7765308_6	414684.RC1_1901	1.11e-126	414.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2TQJI@28211|Alphaproteobacteria,2JR70@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
HSJS3_k127_7765308_16	929703.KE386491_gene4222	1.77e-26	119.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HSJS3_k127_7765308_3	861299.J421_1107	5.353e-178	565.0	COG3391@1|root,COG3391@2|Bacteria,1ZSNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7765308_7	861299.J421_1106	2.672e-125	416.0	COG2010@1|root,COG2010@2|Bacteria,1ZT07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,HupE_UreJ_2
HSJS3_k127_7765308_20	1480694.DC28_02705	5.568e-12	78.0	COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	hoxI	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	EAL,FliG_C,HATPase_c,HisKA,cNMP_binding
HSJS3_k127_7765308_18	243274.THEMA_02235	3.092e-25	113.0	COG2151@1|root,COG2151@2|Bacteria,2GDA3@200918|Thermotogae	200918|Thermotogae	S	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
HSJS3_k127_7765308_8	266117.Rxyl_1756	3.549e-120	394.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4CQIA@84995|Rubrobacteria	84995|Rubrobacteria	S	phenylacetic acid catabolic	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HSJS3_k127_7765308_15	1118054.CAGW01000061_gene2428	5.51e-31	126.0	COG2151@1|root,COG2151@2|Bacteria,1VE3S@1239|Firmicutes,4HKP6@91061|Bacilli	91061|Bacilli	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
HSJS3_k127_7765308_19	1111479.AXAR01000003_gene1557	1.38e-15	78.0	2DTNH@1|root,33M2H@2|Bacteria,1W1AW@1239|Firmicutes,4HZ7K@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7765308_17	1230457.C476_08153	6.064e-26	122.0	COG3396@1|root,arCOG04786@2157|Archaea,2XUT6@28890|Euryarchaeota,23T4K@183963|Halobacteria	183963|Halobacteria	Q	Phenylacetate-CoA oxygenase	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HSJS3_k127_7765308_21	997346.HMPREF9374_3778	9.283e-06	51.0	COG2151@1|root,COG2151@2|Bacteria,1V3QG@1239|Firmicutes,4HHST@91061|Bacilli,27C29@186824|Thermoactinomycetaceae	91061|Bacilli	S	Iron-sulfur cluster assembly protein	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
HSJS3_k127_7765308_22	291985.CCSI01000003_gene235	1.905e-05	55.0	COG1266@1|root,COG1266@2|Bacteria,1MYYZ@1224|Proteobacteria,2UM8W@28211|Alphaproteobacteria,2KAEK@204457|Sphingomonadales	204457|Sphingomonadales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HSJS3_k127_7996587_4	760192.Halhy_0693	6.233e-135	435.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1IPRF@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
HSJS3_k127_7996587_13	1379270.AUXF01000001_gene2506	1.443e-27	115.0	COG1403@1|root,COG1403@2|Bacteria,1ZV49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
HSJS3_k127_7996587_7	661478.OP10G_1068	8.644e-114	397.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
HSJS3_k127_7996587_16	338963.Pcar_0653	7.863e-18	98.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,43S7H@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS3_k127_7996587_10	305700.B447_01516	1.817e-38	149.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,2KX0T@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
HSJS3_k127_7996587_15	1297742.A176_02985	1.033e-18	93.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,4346C@68525|delta/epsilon subdivisions,2X20P@28221|Deltaproteobacteria,2Z2GY@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin reductase like domain	-	-	1.5.1.36	ko:K00484,ko:K16048	ko00350,ko00740,ko00984,ko01100,ko01120,ko01220,map00350,map00740,map00984,map01100,map01120,map01220	-	R02698,R03299,R05705,R09748,R09750,R09819	RC00046,RC00126,RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct,Methyltransf_11
HSJS3_k127_7996587_1	1192034.CAP_3532	5.97e-159	523.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HSJS3_k127_7996587_11	1123252.ATZF01000010_gene417	1.853e-32	136.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,27C7P@186824|Thermoactinomycetaceae	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
HSJS3_k127_7996587_2	518766.Rmar_1907	4.738e-147	493.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HSJS3_k127_7996587_6	251221.35212995	1.414e-125	436.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_7996587_14	1183438.GKIL_3602	4.142e-20	93.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_7996587_0	518766.Rmar_1656	2.828e-289	912.0	COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	2.7.2.4,4.1.1.20	ko:K00928,ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00451,R00480	RC00002,RC00043,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC
HSJS3_k127_7996587_9	886293.Sinac_2431	1.833e-40	172.0	COG2318@1|root,COG2318@2|Bacteria,2IZP2@203682|Planctomycetes	203682|Planctomycetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
HSJS3_k127_7996587_8	517418.Ctha_0981	1.392e-66	250.0	COG4206@1|root,COG4206@2|Bacteria,1FE55@1090|Chlorobi	1090|Chlorobi	M	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HSJS3_k127_7996587_12	1196029.ALIM01000022_gene985	1.951e-30	138.0	COG2866@1|root,COG2866@2|Bacteria,1TS1W@1239|Firmicutes,4HE6H@91061|Bacilli,1ZR8F@1386|Bacillus	91061|Bacilli	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HSJS3_k127_7996587_5	1123257.AUFV01000001_gene1899	3.569e-126	411.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria,1X5WS@135614|Xanthomonadales	135614|Xanthomonadales	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_7996587_3	382464.ABSI01000012_gene2189	4.353e-141	474.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_8021372_15	525904.Tter_2300	1.937e-49	180.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
HSJS3_k127_8021372_0	1121422.AUMW01000026_gene381	4.911e-205	650.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8,1.2.1.99	ko:K00130,ko:K00135,ko:K09472,ko:K22187	ko00040,ko00250,ko00260,ko00310,ko00330,ko00350,ko00650,ko00760,ko01100,ko01120,map00040,map00250,map00260,map00310,map00330,map00350,map00650,map00760,map01100,map01120	M00027,M00136,M00555	R00713,R00714,R02401,R02565,R02566,R07417,R07418,R11768	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HSJS3_k127_8021372_8	443143.GM18_0267	3.196e-71	248.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
HSJS3_k127_8021372_6	1122221.JHVI01000028_gene1302	6.708e-75	256.0	COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
HSJS3_k127_8021372_27	33876.JNXY01000048_gene2429	3.716e-06	58.0	COG0596@1|root,COG0596@2|Bacteria,2HVJX@201174|Actinobacteria,4DHBM@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HSJS3_k127_8021372_12	1429916.X566_21020	3.963e-57	214.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HSJS3_k127_8021372_17	1267211.KI669560_gene557	1.481e-43	167.0	COG0652@1|root,COG0652@2|Bacteria,4NQYP@976|Bacteroidetes	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
HSJS3_k127_8021372_1	861299.J421_1997	9.989e-154	491.0	COG0031@1|root,COG0031@2|Bacteria,1ZTHE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS3_k127_8021372_11	926550.CLDAP_20140	3.76e-63	222.0	COG2193@1|root,COG2193@2|Bacteria,2G6RN@200795|Chloroflexi	200795|Chloroflexi	P	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
HSJS3_k127_8021372_3	379066.GAU_3214	1.412e-118	402.0	28J2H@1|root,2Z8YZ@2|Bacteria,1ZUTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8021372_23	985867.AEWF01000006_gene556	1.795e-23	108.0	COG2346@1|root,COG2346@2|Bacteria,1MZSM@1224|Proteobacteria,2UCHK@28211|Alphaproteobacteria,47FND@766|Rickettsiales	766|Rickettsiales	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	-
HSJS3_k127_8021372_20	1479235.KK366039_gene1982	2.995e-29	122.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria,1XJZ2@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional regulator	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
HSJS3_k127_8021372_19	379066.GAU_2186	1.053e-30	122.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HSJS3_k127_8021372_25	1123242.JH636436_gene271	2.345e-17	85.0	COG1393@1|root,COG1393@2|Bacteria,2J19I@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8021372_5	159450.NH14_30605	6.002e-90	311.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VJI2@28216|Betaproteobacteria,1K0SM@119060|Burkholderiaceae	28216|Betaproteobacteria	EJ	Belongs to the asparaginase 1 family	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HSJS3_k127_8021372_7	1142394.PSMK_10080	3.891e-72	266.0	COG0500@1|root,COG2226@2|Bacteria,2IZB5@203682|Planctomycetes	203682|Planctomycetes	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
HSJS3_k127_8021372_21	518766.Rmar_1082	8.245e-29	126.0	COG4843@1|root,COG4843@2|Bacteria,4NRH5@976|Bacteroidetes	976|Bacteroidetes	S	UPF0316 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
HSJS3_k127_8021372_26	1173020.Cha6605_1045	8.247e-12	76.0	COG3631@1|root,COG3631@2|Bacteria,1G96H@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HSJS3_k127_8021372_10	530564.Psta_0821	2.59e-68	241.0	COG0024@1|root,COG0024@2|Bacteria,2J1QY@203682|Planctomycetes	203682|Planctomycetes	J	Methionine aminopeptidase	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HSJS3_k127_8021372_14	1392838.AWNM01000080_gene2636	4.628e-52	185.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,2VWR8@28216|Betaproteobacteria,3T7XT@506|Alcaligenaceae	28216|Betaproteobacteria	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
HSJS3_k127_8021372_2	378806.STAUR_6541	7.612e-138	451.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YXGA@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HSJS3_k127_8021372_22	522306.CAP2UW1_2595	1.681e-23	111.0	COG3015@1|root,COG3126@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3126@2|Bacteria,COG3187@2|Bacteria,1N8AF@1224|Proteobacteria,2VXB0@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	MliC,YscW
HSJS3_k127_8021372_9	1379270.AUXF01000006_gene55	1.808e-70	252.0	COG0697@1|root,COG0697@2|Bacteria,1ZUKF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS3_k127_8021372_18	324602.Caur_1088	2.684e-42	167.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi,37661@32061|Chloroflexia	32061|Chloroflexia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HSJS3_k127_8021372_4	1379270.AUXF01000002_gene1543	1.534e-110	368.0	COG0252@1|root,COG0252@2|Bacteria,1ZUYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EJ	Asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HSJS3_k127_8021372_13	402626.Rpic_2399	6.166e-53	197.0	COG1216@1|root,COG1216@2|Bacteria,1QV95@1224|Proteobacteria,2VQ6S@28216|Betaproteobacteria,1K0YW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
HSJS3_k127_8021372_24	293826.Amet_4277	3.367e-22	106.0	arCOG06802@1|root,2ZBBG@2|Bacteria,1V17K@1239|Firmicutes,24DHN@186801|Clostridia,36IHR@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8021372_16	926560.KE387027_gene284	4.485e-47	175.0	COG0622@1|root,COG0622@2|Bacteria,1WMMY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HSJS3_k127_8021487_0	500633.CLOHIR_01720	7.448e-150	483.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25QVH@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HSJS3_k127_8021487_1	379066.GAU_1732	6.299e-111	370.0	COG0152@1|root,COG0152@2|Bacteria,1ZT6T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HSJS3_k127_8021487_2	379066.GAU_1734	1.843e-73	259.0	COG1183@1|root,COG1183@2|Bacteria,1ZTJP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HSJS3_k127_8021487_3	379066.GAU_1735	2.109e-21	96.0	COG1828@1|root,COG1828@2|Bacteria,1ZU3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
HSJS3_k127_8021487_4	1280948.HY36_07530	3.356e-07	53.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,43WZQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HSJS3_k127_8059327_2	861299.J421_1064	4.214e-38	149.0	COG0486@1|root,COG0486@2|Bacteria,1ZSRA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HSJS3_k127_8059327_1	1379270.AUXF01000002_gene1186	2.497e-103	357.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
HSJS3_k127_8059327_3	557598.LHK_03237	4.226e-28	118.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KS03@206351|Neisseriales	206351|Neisseriales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HSJS3_k127_8059327_4	861299.J421_1069	1.013e-11	78.0	COG0594@1|root,COG0594@2|Bacteria,1ZV89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HSJS3_k127_8059327_5	379066.GAU_3935	4.525e-10	63.0	COG0230@1|root,COG0230@2|Bacteria,1ZU59@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HSJS3_k127_8059327_0	743719.PaelaDRAFT_2065	1.372e-103	349.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,26QJZ@186822|Paenibacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HSJS3_k127_806726_0	379066.GAU_1291	9.81e-119	387.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HSJS3_k127_806726_1	1122237.AUGQ01000012_gene511	3.964e-22	103.0	COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HSJS3_k127_8079539_13	861299.J421_0336	3.695e-29	119.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_8079539_2	234267.Acid_3515	2.613e-166	559.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_8079539_16	240015.ACP_1550	5.61e-20	94.0	COG1695@1|root,COG1695@2|Bacteria,3Y4WY@57723|Acidobacteria,2JJYG@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_8079539_17	1379270.AUXF01000003_gene3376	1.642e-17	85.0	2DING@1|root,303QG@2|Bacteria,1ZV8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
HSJS3_k127_8079539_18	522772.Dacet_2977	2.761e-07	60.0	COG1664@1|root,COG1664@2|Bacteria,2GFXX@200930|Deferribacteres	200930|Deferribacteres	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HSJS3_k127_8079539_6	28444.JODQ01000008_gene1133	6.774e-95	332.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria,4EP5I@85012|Streptosporangiales	201174|Actinobacteria	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
HSJS3_k127_8079539_14	1183438.GKIL_2903	2.009e-23	104.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_8079539_5	251221.35211765	8.938e-110	390.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_8079539_12	765911.Thivi_1400	2.667e-29	123.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1X17B@135613|Chromatiales	135613|Chromatiales	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
HSJS3_k127_8079539_8	290397.Adeh_0307	1.774e-63	231.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
HSJS3_k127_8079539_10	861299.J421_6122	2.904e-40	169.0	28P8D@1|root,33QB6@2|Bacteria,1ZSQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
HSJS3_k127_8079539_3	861299.J421_6121	1.672e-161	546.0	COG1629@1|root,COG4771@2|Bacteria,1ZT9M@142182|Gemmatimonadetes	861299.J421_6121|-	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8079539_15	1519464.HY22_04215	5.805e-21	105.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HSJS3_k127_8079539_1	379066.GAU_2911	1.148e-210	674.0	COG5276@1|root,COG5276@2|Bacteria,1ZSZX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8079539_9	1267534.KB906756_gene239	8.797e-47	179.0	COG3544@1|root,COG3544@2|Bacteria,3Y4G7@57723|Acidobacteria,2JKAH@204432|Acidobacteriia	204432|Acidobacteriia	P	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
HSJS3_k127_8079539_7	319795.Dgeo_2731	1.012e-72	268.0	COG1228@1|root,COG1228@2|Bacteria,1WIAT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HSJS3_k127_8079539_11	1304874.JAFY01000002_gene300	8.573e-34	151.0	COG0010@1|root,COG0010@2|Bacteria,3T9YE@508458|Synergistetes	508458|Synergistetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HSJS3_k127_8079539_0	926569.ANT_31720	1.594e-228	724.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
HSJS3_k127_8079539_4	1128421.JAGA01000001_gene2194	2.304e-161	523.0	COG2986@1|root,COG2986@2|Bacteria,2NNRU@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
HSJS3_k127_8087745_3	234267.Acid_6481	2.144e-88	295.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_8087745_8	1192034.CAP_5022	2.638e-28	130.0	COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria	1224|Proteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HSJS3_k127_8087745_2	1121920.AUAU01000004_gene751	4.728e-116	385.0	COG1748@1|root,COG1748@2|Bacteria,3Y84N@57723|Acidobacteria	57723|Acidobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
HSJS3_k127_8087745_7	861299.J421_0442	7.367e-32	130.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_8087745_10	861299.J421_0441	0.0002095	53.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
HSJS3_k127_8087745_9	1163617.SCD_n02419	9.76e-17	88.0	COG3064@1|root,COG3064@2|Bacteria,1P2CR@1224|Proteobacteria	1224|Proteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8087745_4	1123059.KB823011_gene1227	1.01e-80	284.0	COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,2TTZC@28211|Alphaproteobacteria,43X6X@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HSJS3_k127_8087745_0	1089550.ATTH01000001_gene1799	3.864e-200	644.0	COG0517@1|root,COG2170@1|root,COG0517@2|Bacteria,COG2170@2|Bacteria,4NGW0@976|Bacteroidetes,1FIUK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
HSJS3_k127_8087745_6	616991.JPOO01000003_gene2479	1.775e-64	250.0	COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,1HZQK@117743|Flavobacteriia,23I9H@178469|Arenibacter	976|Bacteroidetes	E	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
HSJS3_k127_8087745_5	357808.RoseRS_0421	9.679e-77	272.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
HSJS3_k127_8087745_1	1242864.D187_009666	1.541e-118	398.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
HSJS3_k127_8102983_6	521674.Plim_2056	1.198e-21	100.0	COG2172@1|root,COG2172@2|Bacteria,2J0BZ@203682|Planctomycetes	203682|Planctomycetes	T	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
HSJS3_k127_8102983_1	861299.J421_3453	5.945e-97	337.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1ZSPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
HSJS3_k127_8102983_3	861299.J421_3452	4.365e-57	215.0	COG0030@1|root,COG0030@2|Bacteria,1ZT2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HSJS3_k127_8102983_2	379066.GAU_1881	1.029e-61	219.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HSJS3_k127_8102983_4	1379270.AUXF01000006_gene80	7.609e-55	207.0	COG0847@1|root,COG0847@2|Bacteria,1ZTNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HSJS3_k127_8102983_0	861299.J421_3449	1.565e-111	373.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_8102983_5	1382306.JNIM01000001_gene430	5.834e-42	158.0	COG0183@1|root,COG0183@2|Bacteria,2G66E@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HSJS3_k127_8128801_39	479431.Namu_2374	4.813e-46	188.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4EUZ4@85013|Frankiales	201174|Actinobacteria	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
HSJS3_k127_8128801_37	670487.Ocepr_0010	6.697e-55	199.0	COG2316@1|root,COG2316@2|Bacteria,1WJ48@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
HSJS3_k127_8128801_27	379066.GAU_0535	2.375e-80	276.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HSJS3_k127_8128801_46	1122222.AXWR01000029_gene2249	3.298e-23	108.0	COG3824@1|root,COG3824@2|Bacteria,1WJSP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
HSJS3_k127_8128801_11	945713.IALB_0655	9.01e-150	488.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	CP_0468	-	-	ko:K03308,ko:K03466	-	-	-	-	ko00000,ko03036	2.A.22.4,2.A.22.5,3.A.12	-	-	SNF
HSJS3_k127_8128801_34	1121937.AUHJ01000009_gene1566	7.221e-64	222.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,468KZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HSJS3_k127_8128801_3	880073.Calab_2803	2.167e-203	642.0	COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
HSJS3_k127_8128801_43	649638.Trad_2621	1.383e-31	134.0	COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	erpA	-	-	ko:K07400,ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HSJS3_k127_8128801_35	861299.J421_6284	9.326e-63	229.0	COG4242@1|root,COG4242@2|Bacteria,1ZTBM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
HSJS3_k127_8128801_45	479434.Sthe_2189	7.346e-26	113.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_8128801_40	1379270.AUXF01000002_gene1281	1.023e-37	164.0	COG1629@1|root,COG4771@2|Bacteria,1ZU8C@142182|Gemmatimonadetes	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HSJS3_k127_8128801_48	448385.sce1953	8.822e-21	97.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HSJS3_k127_8128801_13	266117.Rxyl_3138	1.718e-131	428.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HSJS3_k127_8128801_12	1121405.dsmv_3219	5.574e-135	462.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,2MHR6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HSJS3_k127_8128801_31	396595.TK90_2008	1.098e-74	269.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
HSJS3_k127_8128801_32	278963.ATWD01000002_gene472	2.232e-74	263.0	COG1209@1|root,COG1209@2|Bacteria	2|Bacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	GalU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HSJS3_k127_8128801_2	1122179.KB890441_gene1057	2.489e-219	700.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1IW3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HSJS3_k127_8128801_38	1380391.JIAS01000001_gene2839	7.261e-53	213.0	COG1287@1|root,COG1287@2|Bacteria,1Q7NF@1224|Proteobacteria,2VDTS@28211|Alphaproteobacteria,2JYAM@204441|Rhodospirillales	204441|Rhodospirillales	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8128801_54	323098.Nwi_0850	6.427e-07	62.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TU56@28211|Alphaproteobacteria,3JZJ1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
HSJS3_k127_8128801_29	373903.Hore_18840	1.95e-78	273.0	COG1215@1|root,COG1215@2|Bacteria,1VS3N@1239|Firmicutes,24XJR@186801|Clostridia,3WBK3@53433|Halanaerobiales	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8128801_53	379066.GAU_2745	3.091e-08	59.0	2CA9X@1|root,2ZJY8@2|Bacteria,1ZU1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8128801_44	1304275.C41B8_18191	2.481e-30	133.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	dmsD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
HSJS3_k127_8128801_0	525909.Afer_1020	0.0	1478.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
HSJS3_k127_8128801_7	525909.Afer_1021	3.615e-174	561.0	COG0437@1|root,COG5557@1|root,COG0437@2|Bacteria,COG5557@2|Bacteria,2H0W0@201174|Actinobacteria,4CNMM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
HSJS3_k127_8128801_49	443143.GM18_1276	2.078e-11	75.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,42UMQ@68525|delta/epsilon subdivisions,2WQY1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
HSJS3_k127_8128801_5	344747.PM8797T_20638	1.035e-183	588.0	COG0415@1|root,COG0415@2|Bacteria,2IXWI@203682|Planctomycetes	203682|Planctomycetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
HSJS3_k127_8128801_10	1379270.AUXF01000003_gene3622	5.266e-158	511.0	COG3391@1|root,COG3391@2|Bacteria,1ZSNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8128801_41	1121918.ARWE01000001_gene188	6.956e-36	144.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,42TD7@68525|delta/epsilon subdivisions,2WPIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
HSJS3_k127_8128801_50	555778.Hneap_1075	3.276e-11	72.0	29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,1S4I9@1236|Gammaproteobacteria,1X0Z0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8128801_26	797304.Natgr_0465	1.479e-88	311.0	COG1232@1|root,arCOG01522@2157|Archaea,2XT3Z@28890|Euryarchaeota,23TW5@183963|Halobacteria	183963|Halobacteria	H	protoporphyrinogen oxidase	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
HSJS3_k127_8128801_19	1261545.MBE-HAL_1355	1.261e-109	381.0	COG0276@1|root,arCOG05373@2157|Archaea,2XTYB@28890|Euryarchaeota,23TSA@183963|Halobacteria	183963|Halobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
HSJS3_k127_8128801_22	1121403.AUCV01000012_gene4020	1.158e-98	340.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2MP6C@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
HSJS3_k127_8128801_9	518766.Rmar_1199	3.816e-158	514.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1FIZB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS3_k127_8128801_42	383372.Rcas_2031	5.817e-33	141.0	COG1587@1|root,COG1587@2|Bacteria,2G70F@200795|Chloroflexi,375S5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Uroporphyrinogen III synthase HEM4	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HSJS3_k127_8128801_30	1120973.AQXL01000116_gene281	7.613e-76	271.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,278YD@186823|Alicyclobacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
HSJS3_k127_8128801_33	1122939.ATUD01000015_gene1015	1.938e-66	244.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CPKE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HSJS3_k127_8128801_17	1121121.KB894306_gene3593	2.353e-116	385.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,26RU4@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HSJS3_k127_8128801_47	1089550.ATTH01000001_gene1551	3.065e-22	107.0	2AB52@1|root,310J6@2|Bacteria,4PF3R@976|Bacteroidetes,1FK3A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8128801_18	314345.SPV1_13177	2.605e-111	370.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria	1224|Proteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HSJS3_k127_8128801_51	861299.J421_4201	1.107e-10	67.0	2CA00@1|root,344QM@2|Bacteria,1ZU1Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8128801_16	744980.TRICHSKD4_0144	4.18e-119	395.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
HSJS3_k127_8128801_20	251221.35214577	1.433e-100	352.0	COG0249@1|root,COG0249@2|Bacteria	2|Bacteria	L	mismatched DNA binding	mutS1	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
HSJS3_k127_8128801_28	243231.GSU2816	6.446e-79	292.0	COG2204@1|root,COG4191@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
HSJS3_k127_8128801_15	930171.Asphe3_35670	2.537e-120	409.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,1W7IC@1268|Micrococcaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HSJS3_k127_8128801_36	379066.GAU_3045	7.547e-57	213.0	COG0491@1|root,COG0491@2|Bacteria,1ZU73@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_8128801_14	504728.K649_04880	7.68e-123	407.0	COG0010@1|root,COG0010@2|Bacteria,1WIEY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HSJS3_k127_8128801_24	401053.AciPR4_2794	3.128e-91	318.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria,2JHRQ@204432|Acidobacteriia	57723|Acidobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS3_k127_8128801_23	248742.XP_005650249.1	1.177e-97	342.0	COG0436@1|root,KOG0257@2759|Eukaryota	2759|Eukaryota	E	transferase activity, transferring nitrogenous groups	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HSJS3_k127_8128801_6	1121939.L861_18095	1.304e-180	576.0	COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Gate
HSJS3_k127_8128801_25	1379270.AUXF01000001_gene2470	3.834e-89	308.0	COG0506@1|root,COG0506@2|Bacteria,1ZT6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HSJS3_k127_8128801_8	1379270.AUXF01000004_gene3193	1.992e-171	558.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
HSJS3_k127_8128801_4	379066.GAU_0118	1.063e-192	611.0	COG2960@1|root,COG2960@2|Bacteria,1ZUAW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
HSJS3_k127_8128801_1	379066.GAU_0117	2.919e-275	872.0	COG0551@1|root,COG0551@2|Bacteria,1ZU9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
HSJS3_k127_8128801_21	314285.KT71_14529	6.529e-99	333.0	COG1402@1|root,COG1402@2|Bacteria,1R4JB@1224|Proteobacteria,1SMBB@1236|Gammaproteobacteria,1J9TE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
HSJS3_k127_8149287_0	562970.Btus_0347	4.592e-184	585.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,278VK@186823|Alicyclobacillaceae	91061|Bacilli	H	ThiC-associated domain	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU08790	ThiC-associated,ThiC_Rad_SAM
HSJS3_k127_8149287_8	886293.Sinac_5806	0.0001205	55.0	COG1807@1|root,COG1807@2|Bacteria,2J1H1@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HSJS3_k127_8149287_6	1161401.ASJA01000009_gene1796	1.873e-26	120.0	2EH1A@1|root,33ATA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8149287_3	926569.ANT_25430	8.085e-127	432.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HSJS3_k127_8149287_2	518766.Rmar_0050	2.323e-147	501.0	COG1629@1|root,COG4796@1|root,COG1629@2|Bacteria,COG4796@2|Bacteria,4PM5G@976|Bacteroidetes,1FKEJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Secretin and TonB N terminus short domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8149287_4	309807.SRU_2250	8.443e-48	186.0	COG3712@1|root,COG3712@2|Bacteria,4PF6H@976|Bacteroidetes,1FK7Q@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HSJS3_k127_8149287_5	1379270.AUXF01000001_gene1940	7.821e-42	161.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyco_hydro_cc,Sigma70_r2,Sigma70_r4_2
HSJS3_k127_8149287_1	761193.Runsl_0557	3.387e-155	503.0	COG0823@1|root,COG1680@1|root,COG0823@2|Bacteria,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,47JBV@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HSJS3_k127_8149287_7	1500894.JQNN01000001_gene3126	3.896e-12	71.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,47606@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_8,Response_reg
HSJS3_k127_828535_2	485913.Krac_3074	5.965e-54	194.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
HSJS3_k127_828535_0	1121918.ARWE01000001_gene3106	1.529e-218	707.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,42N7P@68525|delta/epsilon subdivisions,2WMCJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	-	DUF2156,LPG_synthase_TM
HSJS3_k127_828535_3	290315.Clim_0095	1.291e-42	171.0	COG0347@1|root,COG0347@2|Bacteria,1FF5F@1090|Chlorobi	1090|Chlorobi	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HSJS3_k127_828535_1	96561.Dole_0566	1.257e-165	535.0	COG0004@1|root,COG0004@2|Bacteria,1R50W@1224|Proteobacteria,42PKR@68525|delta/epsilon subdivisions,2WM8P@28221|Deltaproteobacteria,2MII5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HSJS3_k127_8325833_6	379066.GAU_2152	2.703e-97	336.0	COG0481@1|root,COG0481@2|Bacteria,1ZTGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,LepA_C
HSJS3_k127_8325833_28	1379698.RBG1_1C00001G1235	1.633e-09	70.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HSJS3_k127_8325833_8	861299.J421_3749	1.181e-81	284.0	COG1721@1|root,COG1721@2|Bacteria,1ZT0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS3_k127_8325833_14	1379270.AUXF01000003_gene3697	7.763e-66	248.0	COG2304@1|root,COG2304@2|Bacteria,1ZT05@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
HSJS3_k127_8325833_1	518766.Rmar_2754	9.242e-248	806.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1FIP1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HSJS3_k127_8325833_26	1125863.JAFN01000001_gene2568	5.336e-23	113.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
HSJS3_k127_8325833_17	861299.J421_3745	8.816e-59	229.0	COG0760@1|root,COG0760@2|Bacteria,1ZSU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
HSJS3_k127_8325833_11	1125863.JAFN01000001_gene447	1.03e-70	257.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
HSJS3_k127_8325833_10	379066.GAU_2160	4.164e-79	271.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HSJS3_k127_8325833_24	439235.Dalk_4635	5.142e-30	130.0	COG2177@1|root,COG2177@2|Bacteria,1R85B@1224|Proteobacteria,42PXG@68525|delta/epsilon subdivisions,2WKX3@28221|Deltaproteobacteria,2MIBU@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HSJS3_k127_8325833_15	861299.J421_3761	1.001e-65	242.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HSJS3_k127_8325833_21	861299.J421_3797	1.048e-50	204.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
HSJS3_k127_8325833_20	1089551.KE386572_gene4359	6.022e-54	194.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,4BQG0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
HSJS3_k127_8325833_18	644282.Deba_0596	1.171e-56	213.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
HSJS3_k127_8325833_2	861299.J421_3918	1.001e-226	721.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HSJS3_k127_8325833_27	861299.J421_3920	4.703e-18	92.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8325833_9	861299.J421_3861	2.243e-80	279.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
HSJS3_k127_8325833_0	1379270.AUXF01000001_gene2792	1.002e-299	931.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HSJS3_k127_8325833_3	479434.Sthe_2282	6.629e-160	534.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,27YTH@189775|Thermomicrobia	189775|Thermomicrobia	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
HSJS3_k127_8325833_22	886293.Sinac_5507	4.435e-31	127.0	COG0735@1|root,COG0735@2|Bacteria,2J1A1@203682|Planctomycetes	203682|Planctomycetes	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS3_k127_8325833_12	570268.ANBB01000022_gene5160	5.644e-70	259.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4EH36@85012|Streptosporangiales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HSJS3_k127_8325833_32	1540221.JQNI01000002_gene2059	0.000105	55.0	COG0739@1|root,COG0739@2|Bacteria,1WN24@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
HSJS3_k127_8325833_34	497321.C664_19356	0.0005751	51.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria,2KZS6@206389|Rhodocyclales	206389|Rhodocyclales	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
HSJS3_k127_8325833_31	861299.J421_6322	8.018e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1ZV94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
HSJS3_k127_8325833_19	1121930.AQXG01000011_gene1732	1.159e-54	205.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS3_k127_8325833_13	861299.J421_2657	3.562e-69	263.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
HSJS3_k127_8325833_33	589865.DaAHT2_2324	0.000331	52.0	COG3807@1|root,COG3807@2|Bacteria,1RIYJ@1224|Proteobacteria,42SNK@68525|delta/epsilon subdivisions,2WPNS@28221|Deltaproteobacteria,2MK8E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
HSJS3_k127_8325833_29	1379270.AUXF01000003_gene3466	7.125e-08	66.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8325833_7	861299.J421_3927	2.167e-86	308.0	COG0303@1|root,COG0303@2|Bacteria,1ZT4D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HSJS3_k127_8325833_25	765911.Thivi_1600	2.275e-27	119.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1WX4H@135613|Chromatiales	135613|Chromatiales	M	PFAM peptidase	-	-	-	ko:K19304	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	OapA,Peptidase_M23
HSJS3_k127_8325833_5	861299.J421_3930	5.415e-98	330.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HSJS3_k127_8325833_16	945713.IALB_1843	4.163e-64	229.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HSJS3_k127_8325833_4	1117647.M5M_07605	1.614e-152	496.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1J53V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C4-dicarboxylate anaerobic carrier	mleN	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
HSJS3_k127_8325833_23	1122962.AULH01000007_gene1867	2.33e-30	124.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,2U7N6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HSJS3_k127_8368176_0	240016.ABIZ01000001_gene5815	3.242e-71	249.0	COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
HSJS3_k127_8368176_3	385682.AFSL01000008_gene2603	4.033e-16	84.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HSJS3_k127_8368176_1	273068.TTE0841	1.811e-25	116.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,24JM4@186801|Clostridia,42FFZ@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HSJS3_k127_8368176_2	1384054.N790_12760	4.248e-18	88.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1X3IJ@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HSJS3_k127_8439603_2	404589.Anae109_0082	1.539e-102	344.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	peptidase, M16	MA20_05660	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_8439603_1	1379698.RBG1_1C00001G1403	1.414e-115	386.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
HSJS3_k127_8439603_3	861299.J421_4495	1.425e-43	175.0	COG4219@1|root,COG4219@2|Bacteria,1ZUY4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
HSJS3_k127_8439603_4	861299.J421_4494	2.735e-36	148.0	COG3682@1|root,COG3682@2|Bacteria,1ZU4Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HSJS3_k127_8439603_5	861299.J421_5847	8.428e-29	124.0	2E3HM@1|root,30MSF@2|Bacteria,1ZV6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8439603_0	215803.DB30_7235	5.941e-160	539.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	1224|Proteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_8439603_6	861299.J421_6316	3.942e-26	109.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_8441661_7	1121468.AUBR01000030_gene1224	3.33e-51	189.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,42F9Z@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS3_k127_8441661_9	670487.Ocepr_1867	4.6e-45	178.0	COG4665@1|root,COG4665@2|Bacteria,1WJCH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	TRAP-type mannitol chloroaromatic compound transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
HSJS3_k127_8441661_1	518766.Rmar_2648	4.179e-172	550.0	COG4664@1|root,COG4664@2|Bacteria,4PM5T@976|Bacteroidetes,1FIK6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
HSJS3_k127_8441661_10	1242864.D187_010364	2.823e-42	162.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2YXGM@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HSJS3_k127_8441661_6	765912.Thimo_0479	2.177e-84	291.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,1S02F@1236|Gammaproteobacteria,1WXYH@135613|Chromatiales	135613|Chromatiales	S	PFAM O-methyltransferase, family 3	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
HSJS3_k127_8441661_4	1123389.ATXJ01000001_gene867	3.434e-117	391.0	COG4663@1|root,COG4663@2|Bacteria,1WJ6R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
HSJS3_k127_8441661_13	635013.TherJR_2281	9.042e-06	55.0	COG3088@1|root,COG3088@2|Bacteria,1VETA@1239|Firmicutes,24TPT@186801|Clostridia,265EA@186807|Peptococcaceae	186801|Clostridia	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
HSJS3_k127_8441661_3	861299.J421_1321	1.594e-119	392.0	COG0115@1|root,COG0115@2|Bacteria,1ZTH5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HSJS3_k127_8441661_5	861299.J421_6340	2.11e-94	318.0	COG1028@1|root,COG1028@2|Bacteria,1ZTIT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HSJS3_k127_8441661_8	861299.J421_6341	9.814e-46	170.0	COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS3_k127_8441661_2	379066.GAU_2477	9.298e-134	434.0	COG0473@1|root,COG0473@2|Bacteria,1ZTDX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HSJS3_k127_8441661_11	68194.JNXR01000004_gene4565	6.181e-28	129.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
HSJS3_k127_8441661_0	1379270.AUXF01000003_gene3453	9.7e-188	594.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_8441661_12	1191523.MROS_2048	7.975e-28	130.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
HSJS3_k127_8441661_14	765913.ThidrDRAFT_1549	1.512e-05	55.0	COG3005@1|root,COG3005@2|Bacteria,1N8UB@1224|Proteobacteria,1RSJQ@1236|Gammaproteobacteria,1WWBB@135613|Chromatiales	135613|Chromatiales	P	Nitrate TMAO reductase, membrane-bound tetraheme cytochrome c subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Paired_CXXCH_1
HSJS3_k127_8516900_8	1340493.JNIF01000003_gene3677	2.568e-96	322.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
HSJS3_k127_8516900_0	861299.J421_4119	1.187e-195	620.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HSJS3_k127_8516900_17	195250.CM001776_gene934	1.271e-48	178.0	COG2947@1|root,COG2947@2|Bacteria,1G5R2@1117|Cyanobacteria,1H08Y@1129|Synechococcus	1117|Cyanobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
HSJS3_k127_8516900_26	1121285.AUFK01000011_gene314	5.086e-11	69.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HYK4@117743|Flavobacteriia,3ZPS9@59732|Chryseobacterium	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HSJS3_k127_8516900_5	760192.Halhy_3357	6.79e-126	417.0	COG0160@1|root,COG0160@2|Bacteria,4NIHH@976|Bacteroidetes,1IWIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS3_k127_8516900_9	1242864.D187_005627	2.059e-87	316.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YXMW@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG type nucleases (URI domain)	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	UVR
HSJS3_k127_8516900_6	861299.J421_3775	1.593e-121	419.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
HSJS3_k127_8516900_18	861299.J421_3777	4.658e-41	162.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
HSJS3_k127_8516900_7	379066.GAU_0710	2.11e-102	341.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS3_k127_8516900_12	379066.GAU_2851	1.744e-70	252.0	COG1162@1|root,COG1162@2|Bacteria,1ZSSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
HSJS3_k127_8516900_13	861299.J421_3133	2.613e-60	232.0	COG1120@1|root,COG1120@2|Bacteria,1ZTB9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HSJS3_k127_8516900_10	379066.GAU_0496	1.242e-86	300.0	COG0609@1|root,COG0609@2|Bacteria,1ZTAA@142182|Gemmatimonadetes	2|Bacteria	P	FecCD transport family	btuC	-	3.6.3.34	ko:K02013,ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	FecCD
HSJS3_k127_8516900_22	379066.GAU_0497	3.703e-34	145.0	COG0614@1|root,COG0614@2|Bacteria,1ZTIM@142182|Gemmatimonadetes	2|Bacteria	P	Periplasmic binding protein	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HSJS3_k127_8516900_21	999550.KI421507_gene3583	1.613e-36	145.0	COG1853@1|root,COG2267@1|root,COG1853@2|Bacteria,COG2267@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	ntaB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Flavin_Reduct
HSJS3_k127_8516900_20	1379270.AUXF01000004_gene3102	1.616e-38	167.0	COG0420@1|root,COG0420@2|Bacteria,1ZSPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
HSJS3_k127_8516900_27	379066.GAU_0775	9.077e-11	76.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
HSJS3_k127_8516900_23	1499967.BAYZ01000194_gene3125	5.962e-33	134.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HSJS3_k127_8516900_4	861299.J421_2988	2.76e-145	488.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8516900_2	1382356.JQMP01000001_gene806	1.039e-171	574.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Hydantoinaseoxoprolinase domain protein	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
HSJS3_k127_8516900_3	861299.J421_3867	1.153e-167	541.0	COG0147@1|root,COG0147@2|Bacteria,1ZSPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HSJS3_k127_8516900_1	379066.GAU_0444	3.876e-176	563.0	COG0624@1|root,COG0624@2|Bacteria,1ZT2K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HSJS3_k127_8516900_28	861299.J421_2676	1.764e-05	55.0	2FDPQ@1|root,345QV@2|Bacteria,1ZU3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8516900_11	861299.J421_0907	5.883e-77	263.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_8516900_16	861299.J421_3598	3.862e-49	190.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HSJS3_k127_8516900_24	1379270.AUXF01000001_gene2808	2.159e-14	81.0	2C9AX@1|root,33WUH@2|Bacteria,1ZTQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8516900_15	570952.ATVH01000011_gene301	8.817e-53	191.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2JS6P@204441|Rhodospirillales	204441|Rhodospirillales	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS3_k127_8516900_25	85643.Tmz1t_1244	2.286e-14	83.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2VHX5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
HSJS3_k127_8516900_19	404589.Anae109_0944	1.304e-38	148.0	COG2322@1|root,COG2322@2|Bacteria,1NF1F@1224|Proteobacteria,43BE2@68525|delta/epsilon subdivisions,2X6SJ@28221|Deltaproteobacteria,2Z3CM@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
HSJS3_k127_8516900_14	469371.Tbis_0532	7.755e-58	208.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria,4DZH1@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE10	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
HSJS3_k127_8527572_2	379066.GAU_1590	7.199e-98	330.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HSJS3_k127_8527572_3	1379270.AUXF01000006_gene297	6.909e-84	293.0	COG0763@1|root,COG0763@2|Bacteria,1ZTAD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HSJS3_k127_8527572_6	861299.J421_3225	3.849e-45	174.0	COG2121@1|root,COG2121@2|Bacteria,1ZTU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
HSJS3_k127_8527572_5	861299.J421_3226	3.349e-47	189.0	COG1663@1|root,COG1663@2|Bacteria,1ZTIE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
HSJS3_k127_8527572_7	1379270.AUXF01000006_gene293	4.805e-33	142.0	COG1576@1|root,COG1576@2|Bacteria,1ZTQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HSJS3_k127_8527572_4	1047013.AQSP01000125_gene2629	1.066e-70	260.0	COG4365@1|root,COG4365@2|Bacteria,2NP8Q@2323|unclassified Bacteria	2|Bacteria	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HSJS3_k127_8527572_1	861299.J421_3230	6.186e-118	399.0	COG0728@1|root,COG0728@2|Bacteria,1ZTCM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HSJS3_k127_8527572_0	379066.GAU_1598	1.59e-199	640.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
HSJS3_k127_8527572_8	1382306.JNIM01000001_gene1156	4.093e-08	66.0	COG0457@1|root,COG0457@2|Bacteria	1382306.JNIM01000001_gene1156|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_853089_31	278963.ATWD01000001_gene1197	2.759e-20	95.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_853089_30	290512.Paes_1180	9.566e-21	95.0	COG1950@1|root,COG1950@2|Bacteria,1FE4Y@1090|Chlorobi	1090|Chlorobi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
HSJS3_k127_853089_1	861299.J421_0704	3.338e-310	972.0	COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_853089_17	518766.Rmar_1660	8.805e-90	315.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1FJ1Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
HSJS3_k127_853089_19	1131269.AQVV01000016_gene1859	1.295e-80	280.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HSJS3_k127_853089_24	158190.SpiGrapes_0769	2.845e-47	179.0	COG0289@1|root,COG0289@2|Bacteria,2J647@203691|Spirochaetes	203691|Spirochaetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HSJS3_k127_853089_20	861299.J421_3426	2.933e-79	288.0	COG0527@1|root,COG0527@2|Bacteria,1ZSXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HSJS3_k127_853089_16	309801.trd_0366	3.228e-95	326.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,27XNM@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HSJS3_k127_853089_12	1379270.AUXF01000007_gene888	2.08e-130	435.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HSJS3_k127_853089_28	1235457.C404_29410	4.19e-23	104.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VII1@28216|Betaproteobacteria,1K2HH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	similarity to GP 17427840	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
HSJS3_k127_853089_2	1173027.Mic7113_0014	1.463e-295	925.0	COG0531@1|root,COG0531@2|Bacteria,1G248@1117|Cyanobacteria,1H8SD@1150|Oscillatoriales	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
HSJS3_k127_853089_13	518766.Rmar_1790	1.502e-115	388.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes	976|Bacteroidetes	Q	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HSJS3_k127_853089_6	1128421.JAGA01000002_gene1962	3.071e-162	525.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2NQDQ@2323|unclassified Bacteria	2|Bacteria	P	Rhodanese Homology Domain	baeB	-	3.1.2.6,3.4.21.102	ko:K01069,ko:K03797	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000,ko01002	-	-	-	Lactamase_B,Rhodanese
HSJS3_k127_853089_32	1125863.JAFN01000001_gene3054	5.243e-19	100.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria	1224|Proteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
HSJS3_k127_853089_9	861299.J421_2988	1.062e-139	470.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_853089_7	1382359.JIAL01000001_gene1431	9.527e-158	509.0	COG0476@1|root,COG0476@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
HSJS3_k127_853089_11	883.DvMF_0907	3.172e-134	442.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2MA22@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	pyridine nucleotide-disulfide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HSJS3_k127_853089_33	251221.35211248	1.68e-17	86.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_853089_8	215803.DB30_8370	5.282e-141	482.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_853089_3	266117.Rxyl_2540	9.724e-220	702.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HSJS3_k127_853089_35	861299.J421_2311	1.028e-16	84.0	2FKCY@1|root,34C0C@2|Bacteria,1ZU3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_853089_34	525909.Afer_1818	3.737e-17	90.0	COG0586@1|root,COG0586@2|Bacteria,2GKKC@201174|Actinobacteria,4CNDD@84992|Acidimicrobiia	84992|Acidimicrobiia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HSJS3_k127_853089_26	1379270.AUXF01000004_gene3113	1.419e-39	166.0	COG0237@1|root,COG0237@2|Bacteria,1ZTM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HSJS3_k127_853089_18	861299.J421_3916	6.749e-81	282.0	COG0618@1|root,COG0618@2|Bacteria,1ZSS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HSJS3_k127_853089_27	861299.J421_2828	2.528e-36	145.0	COG0735@1|root,COG0735@2|Bacteria,1ZTN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS3_k127_853089_23	1379698.RBG1_1C00001G0708	8.72e-69	246.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HSJS3_k127_853089_14	1234364.AMSF01000016_gene1566	4.681e-102	359.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1X513@135614|Xanthomonadales	135614|Xanthomonadales	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HSJS3_k127_853089_21	379066.GAU_0930	1.738e-78	269.0	COG0785@1|root,COG0785@2|Bacteria,1ZTJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
HSJS3_k127_853089_4	861299.J421_2834	4.145e-164	544.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HSJS3_k127_853089_5	518766.Rmar_2108	2.993e-163	532.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1FIXA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HSJS3_k127_853089_15	861299.J421_2838	5.877e-96	323.0	COG2103@1|root,COG2103@2|Bacteria,1ZT2A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
HSJS3_k127_853089_29	391587.KAOT1_02912	1.511e-22	114.0	COG1807@1|root,COG4642@1|root,COG1807@2|Bacteria,COG4642@2|Bacteria,4PME4@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	MORN
HSJS3_k127_853089_10	861299.J421_2845	1.359e-137	477.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSWP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HSJS3_k127_853089_0	861299.J421_2847	0.0	1044.0	COG0209@1|root,COG0209@2|Bacteria,1ZSU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
HSJS3_k127_853089_25	768066.HELO_3854	9.853e-42	161.0	COG0346@1|root,COG0346@2|Bacteria,1RIN8@1224|Proteobacteria,1S8N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS3_k127_853089_22	1121875.KB907549_gene1714	3.065e-71	253.0	28KH6@1|root,2ZA2R@2|Bacteria,4NI7X@976|Bacteroidetes,1HYH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_853089_36	1047013.AQSP01000139_gene2414	4.35e-08	63.0	COG0457@1|root,COG0457@2|Bacteria,2NRWN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8596576_2	1121930.AQXG01000001_gene1298	6.648e-189	613.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
HSJS3_k127_8596576_8	316274.Haur_0063	0.0003288	48.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi,374X7@32061|Chloroflexia	32061|Chloroflexia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
HSJS3_k127_8596576_1	1379270.AUXF01000005_gene635	8.243e-254	804.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
HSJS3_k127_8596576_0	266117.Rxyl_0316	8.849e-261	823.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HSJS3_k127_8596576_3	379066.GAU_1365	6.282e-144	503.0	COG0297@1|root,COG0297@2|Bacteria,1ZUKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HSJS3_k127_8596576_4	861299.J421_0427	3.262e-136	478.0	COG1449@1|root,COG1449@2|Bacteria,1ZTEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
HSJS3_k127_8596576_5	1123371.ATXH01000006_gene822	3.01e-114	411.0	COG1449@1|root,COG1449@2|Bacteria,2GIGQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Domain of unknown function (DUF1925)	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
HSJS3_k127_8596576_6	1265313.HRUBRA_00481	2.905e-61	222.0	COG1402@1|root,COG1402@2|Bacteria,1R4JB@1224|Proteobacteria	1224|Proteobacteria	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
HSJS3_k127_8596576_7	196490.AUEZ01000001_gene7478	3.012e-05	50.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2TR0X@28211|Alphaproteobacteria,3JV8E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CK	FMN_bind	nosR	-	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4_5
HSJS3_k127_8605645_1	379066.GAU_1458	1.217e-209	672.0	COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,DUF1566,LVIVD,SLH
HSJS3_k127_8605645_5	398720.MED217_08460	8.495e-71	250.0	COG4221@1|root,COG4221@2|Bacteria,4NHEQ@976|Bacteroidetes,1HWXM@117743|Flavobacteriia,2XK19@283735|Leeuwenhoekiella	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS3_k127_8605645_8	1089550.ATTH01000001_gene1862	6.014e-41	162.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1FIK9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Permease MlaE	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HSJS3_k127_8605645_6	1379270.AUXF01000004_gene3177	1.211e-58	213.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HSJS3_k127_8605645_10	313596.RB2501_13264	4.865e-21	105.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HSJS3_k127_8605645_0	518766.Rmar_0629	3.35e-298	955.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
HSJS3_k127_8605645_3	379066.GAU_1210	2.801e-95	328.0	COG4409@1|root,COG4409@2|Bacteria,1ZUBR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8605645_9	391625.PPSIR1_09520	5.954e-27	120.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_8605645_2	215803.DB30_0807	1.173e-108	368.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,42PES@68525|delta/epsilon subdivisions,2WME8@28221|Deltaproteobacteria,2YWIV@29|Myxococcales	28221|Deltaproteobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
HSJS3_k127_8605645_4	1379270.AUXF01000006_gene54	6.471e-94	319.0	COG2870@1|root,COG2870@2|Bacteria,1ZT0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
HSJS3_k127_8605645_7	1125863.JAFN01000001_gene1797	5.242e-42	171.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HSJS3_k127_8605645_11	379066.GAU_1564	0.0001894	49.0	2FIMZ@1|root,34ADU@2|Bacteria,1ZTYV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8670950_7	1386089.N865_16840	3.191e-66	234.0	COG3911@1|root,COG3911@2|Bacteria	2|Bacteria	K	COG3911 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
HSJS3_k127_8670950_5	411474.COPEUT_02209	2.775e-95	330.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia	186801|Clostridia	P	TIGRFAM anion transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
HSJS3_k127_8670950_0	861299.J421_4227	4.986e-219	715.0	COG1629@1|root,COG4771@2|Bacteria,1ZUM3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HSJS3_k127_8670950_6	1379270.AUXF01000004_gene2896	2.599e-73	264.0	28P8D@1|root,33Q3E@2|Bacteria,1ZU8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
HSJS3_k127_8670950_9	251221.35211906	1.258e-58	209.0	COG2249@1|root,COG2249@2|Bacteria,1G57U@1117|Cyanobacteria	1117|Cyanobacteria	S	Flavodoxin-like fold	-	-	-	ko:K03923,ko:K11748	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
HSJS3_k127_8670950_1	331678.Cphamn1_0086	3.103e-210	670.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1FD6D@1090|Chlorobi	1090|Chlorobi	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
HSJS3_k127_8670950_10	861299.J421_6344	1.172e-32	131.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_8670950_3	234267.Acid_1737	3.36e-134	461.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_8670950_4	1280692.AUJL01000008_gene2468	4.403e-128	416.0	COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,2485S@186801|Clostridia,36FJ8@31979|Clostridiaceae	186801|Clostridia	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HSJS3_k127_8670950_2	1122221.JHVI01000022_gene1208	5.676e-152	499.0	COG0156@1|root,COG0156@2|Bacteria,1WIXA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_8670950_11	1449076.JOOE01000004_gene189	3.913e-11	70.0	COG3909@1|root,COG3909@2|Bacteria,1Q594@1224|Proteobacteria,2UG98@28211|Alphaproteobacteria,2K7WU@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
HSJS3_k127_8670950_8	1379270.AUXF01000007_gene915	1.044e-61	225.0	2CESB@1|root,2Z8UZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8778537_0	1121920.AUAU01000018_gene1826	1.755e-49	184.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
HSJS3_k127_8778537_1	880073.Calab_3408	3.263e-34	147.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
HSJS3_k127_8822400_11	861299.J421_3032	2.787e-21	106.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZTF0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HSJS3_k127_8822400_7	9031.ENSGALP00000009883	1.861e-60	220.0	COG0329@1|root,2QWNS@2759|Eukaryota,399HY@33154|Opisthokonta,3BGNT@33208|Metazoa,3CUM9@33213|Bilateria,481FN@7711|Chordata,48XJ6@7742|Vertebrata,4GT29@8782|Aves	33208|Metazoa	E	4-hydroxy-2-oxoglutarate aldolase	HOGA1	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.1.3.16	ko:K18123	ko00330,ko00630,ko01100,map00330,map00630,map01100	-	R00470,R00471	RC00307,RC00308	ko00000,ko00001,ko01000	-	-	-	DHDPS
HSJS3_k127_8822400_4	1379270.AUXF01000004_gene3004	7.516e-131	428.0	COG2805@1|root,COG2805@2|Bacteria,1ZT2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HSJS3_k127_8822400_5	237368.SCABRO_01228	1.907e-119	393.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1b
HSJS3_k127_8822400_8	227377.CBU_1133	8.605e-54	200.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1JCIP@118969|Legionellales	118969|Legionellales	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HSJS3_k127_8822400_0	861299.J421_2166	2.666e-266	838.0	COG1529@1|root,COG1529@2|Bacteria,1ZSUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HSJS3_k127_8822400_6	1379270.AUXF01000001_gene2420	2.844e-63	224.0	COG2080@1|root,COG2080@2|Bacteria,1ZTHW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HSJS3_k127_8822400_9	944481.JAFP01000001_gene1269	2.613e-28	121.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2M76J@213113|Desulfurellales	28221|Deltaproteobacteria	O	CS domain	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HSJS3_k127_8822400_10	485913.Krac_8141	1.572e-26	121.0	COG2971@1|root,COG2971@2|Bacteria,2G6Y6@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HSJS3_k127_8822400_2	1379270.AUXF01000003_gene3853	5.825e-147	480.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HSJS3_k127_8822400_1	518766.Rmar_0925	3.066e-212	700.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
HSJS3_k127_8822400_3	861299.J421_3604	1.158e-143	480.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
HSJS3_k127_8830657_3	1283300.ATXB01000001_gene2015	0.000355	46.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1XDIM@135618|Methylococcales	135618|Methylococcales	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HSJS3_k127_8830657_2	41431.PCC8801_1300	9.085e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,1GIT8@1117|Cyanobacteria,3KHZU@43988|Cyanothece	1117|Cyanobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8,Trypsin_2
HSJS3_k127_8830657_1	1121937.AUHJ01000011_gene2889	2.83e-160	514.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
HSJS3_k127_8830657_0	215803.DB30_8370	1.012e-169	563.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_9078932_8	469371.Tbis_0981	6.567e-20	94.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4E2W5@85010|Pseudonocardiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HSJS3_k127_9078932_1	861299.J421_3824	4.559e-99	327.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HSJS3_k127_9078932_3	861299.J421_2221	1.222e-65	241.0	2ECQU@1|root,336NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PHP
HSJS3_k127_9078932_2	861299.J421_2056	1.664e-95	339.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HSJS3_k127_9078932_9	395961.Cyan7425_2162	5.205e-16	92.0	COG2242@1|root,COG2242@2|Bacteria,1G3ZR@1117|Cyanobacteria,3KGHB@43988|Cyanothece	1117|Cyanobacteria	H	methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HSJS3_k127_9078932_6	1120972.AUMH01000011_gene239	1.55e-38	157.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HSJS3_k127_9078932_4	107635.AZUO01000001_gene2828	4.578e-53	196.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,36YDE@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HSJS3_k127_9078932_0	861299.J421_5712	1.794e-158	537.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_5712|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9078932_5	861299.J421_2218	1.921e-39	152.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_9078932_7	1499967.BAYZ01000159_gene545	1.828e-33	139.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_4_9,Exo_endo_phos,F5_F8_type_C,FIVAR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N
HSJS3_k127_9202551_0	1265313.HRUBRA_01348	2.607e-78	281.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
HSJS3_k127_9202551_1	743721.Psesu_2270	2.022e-08	66.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
HSJS3_k127_9255546_0	1385515.N791_05215	8.146e-135	440.0	COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1X65W@135614|Xanthomonadales	135614|Xanthomonadales	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HSJS3_k127_9255546_2	1218075.BAYA01000003_gene845	1.093e-21	104.0	COG0666@1|root,COG0666@2|Bacteria,1RG3W@1224|Proteobacteria,2VXC0@28216|Betaproteobacteria,1KFIJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Ankyrin repeats (many copies)	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
HSJS3_k127_9255546_1	335543.Sfum_0899	1.147e-103	348.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2MRD0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
HSJS3_k127_9306695_2	309807.SRU_0542	3.959e-60	216.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
HSJS3_k127_9306695_3	1201293.AKXQ01000003_gene2551	1.088e-53	203.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
HSJS3_k127_9306695_0	518766.Rmar_2467	2.312e-151	488.0	COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes	976|Bacteroidetes	P	Chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HSJS3_k127_9306695_1	420246.GTNG_1290	3.522e-119	397.0	COG3876@1|root,COG3876@2|Bacteria,1VRMG@1239|Firmicutes,4HA8F@91061|Bacilli,1WFX8@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF1343)	ybbC	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HSJS3_k127_9334085_4	1260251.SPISAL_03315	6.011e-50	179.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S5BM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phospholipid-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
HSJS3_k127_9334085_2	483219.LILAB_16300	1.096e-80	281.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,439QP@68525|delta/epsilon subdivisions,2X537@28221|Deltaproteobacteria,2Z01T@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix domain	dpbF	-	-	-	-	-	-	-	-	-	-	-	HHH_5,HHH_8
HSJS3_k127_9334085_1	1146883.BLASA_1145	5.075e-81	285.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4EVS8@85013|Frankiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
HSJS3_k127_9334085_3	1499967.BAYZ01000145_gene6200	7.869e-66	231.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
HSJS3_k127_9334085_6	1121920.AUAU01000004_gene593	3.384e-29	120.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
HSJS3_k127_9334085_5	243090.RB621	3.669e-43	165.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
HSJS3_k127_9334085_0	1267533.KB906735_gene5020	1.624e-121	422.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
HSJS3_k127_9334085_7	317936.Nos7107_0143	1.986e-05	59.0	COG1749@1|root,COG5492@1|root,COG1749@2|Bacteria,COG5492@2|Bacteria,1G2ZW@1117|Cyanobacteria	1117|Cyanobacteria	N	Ig domain protein group 1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,DUF4082
HSJS3_k127_9423999_11	1123377.AUIV01000020_gene2477	5.471e-07	52.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,1RQUG@1236|Gammaproteobacteria,1X59Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
HSJS3_k127_9423999_3	1051501.AYTL01000028_gene1871	5.928e-113	380.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,1ZCZN@1386|Bacillus	91061|Bacilli	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
HSJS3_k127_9423999_7	251229.Chro_4000	6.088e-59	214.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,3VK4S@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HSJS3_k127_9423999_1	984262.SGRA_1697	1.286e-147	483.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1IQIE@117747|Sphingobacteriia	976|Bacteroidetes	S	FAD-dependent dehydrogenase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
HSJS3_k127_9423999_9	861299.J421_0637	2.827e-15	79.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0637|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9423999_10	740709.A10D4_05457	1.292e-10	68.0	2EK6E@1|root,33DWT@2|Bacteria,1NJFR@1224|Proteobacteria,1SHVU@1236|Gammaproteobacteria,2QGGK@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
HSJS3_k127_9423999_6	908612.HMPREF9720_1882	9.259e-61	221.0	COG1216@1|root,COG1216@2|Bacteria,4PKFB@976|Bacteroidetes,2FSAV@200643|Bacteroidia,22VCA@171550|Rikenellaceae	976|Bacteroidetes	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
HSJS3_k127_9423999_5	314285.KT71_09537	9.707e-95	321.0	2DUWV@1|root,33SRV@2|Bacteria,1QQST@1224|Proteobacteria,1SKRU@1236|Gammaproteobacteria,1J990@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
HSJS3_k127_9423999_14	204669.Acid345_2760	5.224e-06	55.0	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HSJS3_k127_9423999_8	523791.Kkor_0590	4.367e-31	136.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XRBY@135619|Oceanospirillales	135619|Oceanospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_9423999_13	1233950.IW22_23100	2.179e-06	59.0	29A5Q@1|root,2ZX6Q@2|Bacteria,4NP43@976|Bacteroidetes,1I3P0@117743|Flavobacteriia,3ZQYM@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9423999_12	1125863.JAFN01000001_gene3358	8.365e-07	59.0	2DYDA@1|root,34983@2|Bacteria,1N38S@1224|Proteobacteria,4318W@68525|delta/epsilon subdivisions,2WWC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
HSJS3_k127_9423999_0	1122179.KB890419_gene24	0.0	1045.0	COG4447@1|root,COG4447@2|Bacteria,4NI14@976|Bacteroidetes	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HSJS3_k127_9423999_4	477641.MODMU_4191	2.727e-98	345.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4EV6E@85013|Frankiales	201174|Actinobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
HSJS3_k127_9423999_2	1121937.AUHJ01000011_gene2889	2.991e-120	400.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
HSJS3_k127_9423999_16	1449338.JQLU01000005_gene3179	0.000629	51.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,27GIM@186828|Carnobacteriaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ywkD	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
HSJS3_k127_9423999_15	485913.Krac_5098	0.0003851	45.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_9568337_1	861299.J421_3088	1.154e-50	198.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
HSJS3_k127_9568337_0	1173028.ANKO01000114_gene6142	2.607e-177	580.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,1H9GG@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HSJS3_k127_9755446_1	1121413.JMKT01000009_gene1936	1.17e-78	273.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2WJR5@28221|Deltaproteobacteria,2MAEE@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	LysM,MS_channel,TM_helix
HSJS3_k127_9755446_0	385682.AFSL01000102_gene55	3.89e-294	920.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
HSJS3_k127_9755446_2	945713.IALB_0509	1.872e-76	268.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
HSJS3_k127_9755446_4	1202962.KB907160_gene3401	7.589e-26	117.0	COG0428@1|root,COG0701@1|root,COG4531@1|root,COG0428@2|Bacteria,COG0701@2|Bacteria,COG4531@2|Bacteria,1R5Z4@1224|Proteobacteria,1RY3U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
HSJS3_k127_9755446_3	517722.AEUE01000010_gene614	5.104e-37	150.0	COG1416@1|root,COG1416@2|Bacteria,1RI2V@1224|Proteobacteria,2U98Z@28211|Alphaproteobacteria,2K5CI@204457|Sphingomonadales	204457|Sphingomonadales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
HSJS3_k127_9755446_5	1134912.AJTV01000025_gene2730	6.526e-23	102.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,36XPA@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HSJS3_k127_9776084_0	234267.Acid_5446	1.802e-86	300.0	COG0665@1|root,COG0665@2|Bacteria,3Y3W7@57723|Acidobacteria	57723|Acidobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
HSJS3_k127_9781446_1	1121035.AUCH01000005_gene125	6.038e-66	238.0	COG2199@1|root,COG3706@2|Bacteria,1MYK0@1224|Proteobacteria	1224|Proteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
HSJS3_k127_9781446_2	861299.J421_0305	6.396e-31	135.0	COG1413@1|root,COG1413@2|Bacteria,1ZTU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
HSJS3_k127_9781446_0	861299.J421_0306	9.684e-71	257.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
HSJS3_k127_9804623_0	861299.J421_0332	1.18e-43	179.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0332|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9804623_2	1348114.OM33_12095	5.391e-20	102.0	COG1695@1|root,COG1695@2|Bacteria,1NBHS@1224|Proteobacteria,1T1AU@1236|Gammaproteobacteria,2Q5G1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_9804623_3	178901.AmDm5_0209	2.167e-06	58.0	COG3577@1|root,COG3577@2|Bacteria,1N45S@1224|Proteobacteria,2UGU4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
HSJS3_k127_9804623_1	1379270.AUXF01000001_gene1925	8.97e-24	105.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56,SHD1
HSJS3_k127_9855031_7	1150469.RSPPHO_02781	1.851e-06	52.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9855031_5	272624.lpg1742	3.058e-14	85.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9855031_6	1121930.AQXG01000001_gene1539	3.957e-13	81.0	2C4JB@1|root,30BI1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9855031_3	1280947.HY30_12510	1.062e-32	137.0	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,2UGMI@28211|Alphaproteobacteria,43Y8Q@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HSJS3_k127_9855031_1	309807.SRU_2374	5.339e-156	508.0	COG1233@1|root,COG1233@2|Bacteria,4P1B3@976|Bacteroidetes,1FIWM@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	Q	Flavin containing amine oxidoreductase	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
HSJS3_k127_9855031_0	661478.OP10G_0832	2.97e-160	532.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
HSJS3_k127_9855031_2	552811.Dehly_1358	2.889e-60	225.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,34CQG@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HSJS3_k127_9855031_4	443598.AUFA01000015_gene6774	3.854e-26	125.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2TR0X@28211|Alphaproteobacteria,3JV8E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CK	FMN_bind	nosR	-	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4_5
HSJS3_k127_9936548_0	748247.AZKH_2442	1.277e-59	212.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,2VQH7@28216|Betaproteobacteria,2KZ16@206389|Rhodocyclales	206389|Rhodocyclales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HSJS3_k127_9936548_2	518766.Rmar_0373	6.159e-12	77.0	COG0457@1|root,COG0457@2|Bacteria,4PJ45@976|Bacteroidetes,1FJJ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HSJS3_k127_9936548_1	694427.Palpr_2946	2.763e-20	95.0	2BFHQ@1|root,329BH@2|Bacteria,4P73M@976|Bacteroidetes,2FZWT@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9936548_3	1406840.Q763_16590	6.339e-06	56.0	28JZK@1|root,2Z9PJ@2|Bacteria,4NIWX@976|Bacteroidetes,1I16C@117743|Flavobacteriia,2NXXN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 2352 queries scanned
## Total time (seconds): 204.5456941127777
## Rate: 11.50 q/s