## Fri Nov 15 05:58:04 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin11/HSJS_3_bin.38.fa -m mmseqs --itype genome -o HSJS_3_bin.38 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HSJS_3_bin.38 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HSJS3_k127_10032673_0	8010.XP_010884430.1	1.695e-67	248.0	COG1034@1|root,KOG2282@2759|Eukaryota,38DHR@33154|Opisthokonta,3BE04@33208|Metazoa,3CT34@33213|Bilateria,482GT@7711|Chordata,492Y4@7742|Vertebrata,49RE6@7898|Actinopterygii	33208|Metazoa	C	75 kDa subunit	NDUFS1	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005758,GO:0005759,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0008219,GO:0008637,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010257,GO:0012501,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042391,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0050136,GO:0051536,GO:0051540,GO:0051881,GO:0055086,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0072593,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3,1.6.99.3	ko:K03934	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
HSJS3_k127_10057324_1	1396418.BATQ01000186_gene2187	4.067e-32	134.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia,2IVSK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_10057324_2	1123308.KB904557_gene1155	1.131e-19	101.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli	91061|Bacilli	S	hydrolase of the HAD superfamily	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
HSJS3_k127_10057324_0	543728.Vapar_2796	6.166e-37	154.0	COG0590@1|root,COG0596@1|root,COG0590@2|Bacteria,COG0596@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,4A9VR@80864|Comamonadaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
HSJS3_k127_10174335_4	1227484.C471_07495	4.813e-05	55.0	COG2132@1|root,COG3291@1|root,arCOG11135@1|root,arCOG02546@2157|Archaea,arCOG03914@2157|Archaea,arCOG11135@2157|Archaea,2XZZB@28890|Euryarchaeota,23Y8X@183963|Halobacteria	183963|Halobacteria	Q	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
HSJS3_k127_10174335_0	357808.RoseRS_1917	6.78e-168	539.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi,37708@32061|Chloroflexia	32061|Chloroflexia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
HSJS3_k127_10174335_1	641491.DND132_1319	9.925e-47	173.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2MBFG@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HSJS3_k127_10174335_2	644282.Deba_2646	2.583e-26	115.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
HSJS3_k127_10174335_3	1282876.BAOK01000001_gene3173	3.567e-22	99.0	COG0640@1|root,COG0640@2|Bacteria,1ND8B@1224|Proteobacteria,2UI6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HSJS3_k127_10223304_1	1048834.TC41_0555	2.349e-47	177.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,2786V@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HSJS3_k127_10223304_2	479436.Vpar_0522	5.57e-44	169.0	COG0767@1|root,COG0767@2|Bacteria,1U95A@1239|Firmicutes,4H2EU@909932|Negativicutes	909932|Negativicutes	Q	Belongs to the MlaE permease family	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HSJS3_k127_10223304_0	1123371.ATXH01000005_gene2034	1.432e-58	218.0	COG1127@1|root,COG1127@2|Bacteria,2GH9S@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HSJS3_k127_10223304_3	313612.L8106_30620	1.341e-06	60.0	COG1463@1|root,COG1463@2|Bacteria,1G1A7@1117|Cyanobacteria,1H92R@1150|Oscillatoriales	1117|Cyanobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	ycf22	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HSJS3_k127_10242263_1	1125700.HMPREF9195_00374	5.026e-14	72.0	COG1351@1|root,COG1351@2|Bacteria,2J68R@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HSJS3_k127_10242263_0	706587.Desti_2787	2.335e-105	355.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
HSJS3_k127_10301613_6	1232452.BAIB02000016_gene2510	0.0002115	47.0	COG3613@1|root,COG3613@2|Bacteria,1TV14@1239|Firmicutes,24VW7@186801|Clostridia	186801|Clostridia	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_10301613_0	401526.TcarDRAFT_0399	3.433e-128	429.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H34D@909932|Negativicutes	909932|Negativicutes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HSJS3_k127_10301613_1	1313421.JHBV01000016_gene5682	2.893e-102	346.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HSJS3_k127_10301613_5	1266909.AUAG01000024_gene1749	4.843e-27	124.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1WZ62@135613|Chromatiales	135613|Chromatiales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
HSJS3_k127_10301613_4	748449.Halha_0434	1.608e-34	141.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WC9Q@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HSJS3_k127_10301613_2	1489678.RDMS_13645	3.522e-73	267.0	COG0539@1|root,COG0539@2|Bacteria,1WJGM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HSJS3_k127_10301613_3	1211035.CD30_13825	5.774e-52	187.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4HB2M@91061|Bacilli,3IZ8D@400634|Lysinibacillus	91061|Bacilli	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HSJS3_k127_10336090_0	632518.Calow_0751	3.266e-131	437.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,42FGH@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HSJS3_k127_10336090_3	543728.Vapar_3244	1.684e-08	62.0	COG1051@1|root,COG1051@2|Bacteria,1N9PU@1224|Proteobacteria,2W4CW@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HSJS3_k127_10336090_2	485913.Krac_1332	1.345e-18	89.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HSJS3_k127_10336090_1	661478.OP10G_0103	6.285e-111	365.0	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HSJS3_k127_10484253_1	1047013.AQSP01000122_gene2223	7.333e-11	74.0	COG3291@1|root,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,CHU_C,FlgD_ig,Glyco_hydro_6,PKD,VCBS
HSJS3_k127_10484253_0	696281.Desru_3371	1.55e-56	218.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,260IB@186807|Peptococcaceae	186801|Clostridia	O	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_10484253_2	246197.MXAN_5332	1.919e-09	63.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2X58U@28221|Deltaproteobacteria,2YX0P@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_10499276_2	234267.Acid_5686	3.668e-23	105.0	COG0839@1|root,COG0839@2|Bacteria,3Y5QU@57723|Acidobacteria	57723|Acidobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HSJS3_k127_10499276_3	1408424.JHYI01000015_gene4740	1.585e-22	105.0	COG0713@1|root,COG0713@2|Bacteria,1V9Z8@1239|Firmicutes,4HJ9Q@91061|Bacilli,1ZGXH@1386|Bacillus	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HSJS3_k127_10499276_1	512565.AMIS_5670	1.343e-41	175.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4D9JY@85008|Micromonosporales	201174|Actinobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
HSJS3_k127_10499276_0	1232410.KI421424_gene1793	5.434e-83	293.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,43TUC@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HSJS3_k127_10519041_0	608538.HTH_1851	1.289e-59	219.0	COG0604@1|root,COG0604@2|Bacteria,2G4NX@200783|Aquificae	200783|Aquificae	C	Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_10519041_1	742767.HMPREF9456_01762	4.359e-49	185.0	COG1266@1|root,COG1266@2|Bacteria,4P35E@976|Bacteroidetes,2FQQ0@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HSJS3_k127_10519041_2	563192.HMPREF0179_00489	5.158e-42	165.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42U8Q@68525|delta/epsilon subdivisions,2X5AX@28221|Deltaproteobacteria,2MDIT@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HSJS3_k127_10594835_0	1379698.RBG1_1C00001G0785	1.149e-108	368.0	COG1541@1|root,COG1541@2|Bacteria,2NREC@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
HSJS3_k127_10594835_2	1150599.MPHLEI_04138	4.685e-08	62.0	COG5473@1|root,COG5473@2|Bacteria,2GN5K@201174|Actinobacteria,234B0@1762|Mycobacteriaceae	201174|Actinobacteria	J	Zn-ribbon protein possibly nucleic acid-binding	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_10594835_1	330214.NIDE2488	2.157e-76	263.0	28II6@1|root,2Z8JB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1067424_2	1210908.HSB1_14360	8.188e-19	86.0	2E4PM@1|root,2N5ZN@2157|Archaea,2XY56@28890|Euryarchaeota,23W7K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1067424_1	1160707.AJIK01000001_gene276	4.613e-41	168.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,26CY1@186818|Planococcaceae	91061|Bacilli	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HSJS3_k127_1067424_3	886293.Sinac_6587	1.104e-18	93.0	COG1595@1|root,COG1595@2|Bacteria,2IZMT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HSJS3_k127_1067424_0	1254432.SCE1572_32635	9.129e-70	238.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2YZE8@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
HSJS3_k127_11331_1	710393.HSUHS1_0451	5.742e-23	103.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
HSJS3_k127_11331_0	1195236.CTER_1145	1.804e-53	194.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,3WHE8@541000|Ruminococcaceae	186801|Clostridia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HSJS3_k127_1163549_4	1128421.JAGA01000002_gene792	0.0001407	48.0	arCOG11507@1|root,333W5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1163549_2	1499967.BAYZ01000074_gene2091	1.521e-17	97.0	COG0286@1|root,COG1196@1|root,COG0286@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4041,Methylase_S,N6_Mtase,PSCyt2,PSD1
HSJS3_k127_1163549_0	479434.Sthe_1296	1.077e-54	201.0	COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi,27Y6N@189775|Thermomicrobia	189775|Thermomicrobia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HSJS3_k127_1163549_1	251229.Chro_4831	6.663e-50	193.0	COG0204@1|root,COG0204@2|Bacteria,1G3F1@1117|Cyanobacteria,3VJGW@52604|Pleurocapsales	1117|Cyanobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
HSJS3_k127_1163549_3	1463841.JOIR01000043_gene1226	1.424e-07	63.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8
HSJS3_k127_121557_7	7739.XP_002587131.1	6.302e-06	56.0	KOG1216@1|root,KOG1948@1|root,KOG1216@2759|Eukaryota,KOG1948@2759|Eukaryota,38EKX@33154|Opisthokonta,3BBHT@33208|Metazoa,3CSTB@33213|Bilateria,4850W@7711|Chordata	33208|Metazoa	O	carbohydrate binding	NOMO1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0012505,GO:0016020,GO:0031984,GO:0032991,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0098827	-	ko:K21988	-	-	-	-	ko00000,ko02000	1.A.17.4	-	-	CarboxypepD_reg,TMC
HSJS3_k127_121557_6	1173028.ANKO01000170_gene3389	1.387e-06	60.0	COG0488@1|root,COG0488@2|Bacteria,1G0I1@1117|Cyanobacteria,1H6YE@1150|Oscillatoriales	1117|Cyanobacteria	S	of ABC transporters with duplicated ATPase	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HSJS3_k127_121557_4	1246995.AFR_01880	2.337e-08	61.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,4DE05@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
HSJS3_k127_121557_2	1410628.JNKS01000004_gene2198	2.132e-39	156.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,27MET@186928|unclassified Lachnospiraceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HSJS3_k127_121557_3	1385518.N798_10445	5.837e-21	103.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria,4FHQV@85021|Intrasporangiaceae	201174|Actinobacteria	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
HSJS3_k127_121557_5	32507.XP_006811092.1	4.412e-08	64.0	2D0CX@1|root,2SDQB@2759|Eukaryota,39SY8@33154|Opisthokonta,3BKH2@33208|Metazoa,3D53Q@33213|Bilateria,47ZJI@7711|Chordata,496HQ@7742|Vertebrata,4A0PY@7898|Actinopterygii	33208|Metazoa	S	Glycine N-acyltransferase-like	GLYAT	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005813,GO:0005815,GO:0005856,GO:0006082,GO:0006139,GO:0006163,GO:0006520,GO:0006544,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006805,GO:0006807,GO:0008092,GO:0008150,GO:0008152,GO:0009069,GO:0009117,GO:0009150,GO:0009259,GO:0009410,GO:0009636,GO:0009987,GO:0015630,GO:0015631,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042133,GO:0042221,GO:0043015,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0047961,GO:0047962,GO:0050896,GO:0051186,GO:0051716,GO:0055086,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071466,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901787	2.3.1.13,2.3.1.192,2.3.1.71	ko:K00628,ko:K15517	ko00360,map00360	-	R02452,R05841	RC00004,RC00096,RC02865,RC02867	ko00000,ko00001,ko01000	-	-	-	Gly_acyl_tr_C,Gly_acyl_tr_N
HSJS3_k127_121557_1	344747.PM8797T_11846	1.95e-75	260.0	COG3880@1|root,COG3880@2|Bacteria,2IYYJ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
HSJS3_k127_121557_0	344747.PM8797T_11851	5.628e-91	317.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2IXNQ@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase, iron-sulfur binding subunit	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
HSJS3_k127_128320_1	266117.Rxyl_0171	2.543e-95	321.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CPSF@84995|Rubrobacteria	84995|Rubrobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HSJS3_k127_128320_0	266117.Rxyl_0170	1.675e-214	675.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
HSJS3_k127_132726_7	1045855.DSC_06220	7.066e-05	54.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1X69D@135614|Xanthomonadales	135614|Xanthomonadales	M	Polysaccharide biosynthesis protein GumB	gumB	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
HSJS3_k127_132726_2	525904.Tter_2814	5.196e-83	287.0	COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HSJS3_k127_132726_3	745014.OMB55_00004120	1.352e-34	141.0	COG0299@1|root,COG0666@1|root,COG0299@2|Bacteria,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	purN	-	2.1.2.2,2.1.2.9	ko:K00604,ko:K03086,ko:K11175	ko00230,ko00670,ko00970,ko01100,ko01110,ko01130,map00230,map00670,map00970,map01100,map01110,map01130	M00048	R03940,R04325,R04326	RC00026,RC00165,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Formyl_trans_N,YjbR
HSJS3_k127_132726_0	1379698.RBG1_1C00001G0637	1.102e-161	521.0	COG0677@1|root,COG0677@2|Bacteria,2NNQ1@2323|unclassified Bacteria	2|Bacteria	M	UDP binding domain	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HSJS3_k127_132726_5	521095.Apar_0980	3.877e-25	120.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4CVDQ@84998|Coriobacteriia	84998|Coriobacteriia	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
HSJS3_k127_132726_1	357808.RoseRS_4428	6.673e-124	407.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HSJS3_k127_132726_6	1462527.CCDM010000003_gene4236	9.365e-19	91.0	COG1633@1|root,COG1633@2|Bacteria,1V4ZN@1239|Firmicutes,4HH0Q@91061|Bacilli,23KAI@182709|Oceanobacillus	91061|Bacilli	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
HSJS3_k127_132726_8	522306.CAP2UW1_1412	0.0001033	55.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Polysaccharide chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
HSJS3_k127_132726_4	1117108.PAALTS15_10344	4.33e-29	125.0	COG3307@1|root,COG3307@2|Bacteria,1VADQ@1239|Firmicutes,4HN52@91061|Bacilli	91061|Bacilli	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HSJS3_k127_1332028_0	632292.Calhy_1196	3.537e-139	449.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,42EWA@68295|Thermoanaerobacterales	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HSJS3_k127_1332028_4	324602.Caur_1565	6.186e-60	219.0	COG1024@1|root,COG1024@2|Bacteria,2G7Z4@200795|Chloroflexi,375KM@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
HSJS3_k127_1332028_7	1396.DJ87_2793	0.0002686	54.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HBE4@91061|Bacilli,1ZD5Z@1386|Bacillus	91061|Bacilli	M	Spore Coat	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
HSJS3_k127_1332028_2	1121430.JMLG01000011_gene344	6.11e-95	320.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,260TJ@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HSJS3_k127_1332028_1	316274.Haur_4364	1.157e-121	417.0	COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi,374YF@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
HSJS3_k127_1332028_3	1423754.BALY01000022_gene938	7.787e-90	312.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HSJS3_k127_1332028_6	926569.ANT_09460	8.382e-21	106.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
HSJS3_k127_1332028_5	1408424.JHYI01000047_gene1635	3.219e-43	169.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,1ZBIU@1386|Bacillus	91061|Bacilli	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HSJS3_k127_1343363_1	1121937.AUHJ01000009_gene1566	5.217e-53	194.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,468KZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HSJS3_k127_1343363_0	398767.Glov_1762	2.095e-76	268.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1NTJT@1224|Proteobacteria,42NK8@68525|delta/epsilon subdivisions,2WIM0@28221|Deltaproteobacteria,43TCJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
HSJS3_k127_1347839_2	635013.TherJR_1929	6.235e-45	174.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,260JN@186807|Peptococcaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
HSJS3_k127_1347839_1	35841.BT1A1_3283	1.206e-126	413.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1ZBFX@1386|Bacillus	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HSJS3_k127_1347839_0	1307759.JOMJ01000003_gene1862	2.22e-150	489.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2M8XA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HSJS3_k127_1347839_3	518766.Rmar_1033	1.577e-35	142.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1FJDH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HSJS3_k127_1347839_4	1077285.AGDG01000002_gene2075	2.547e-22	103.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,2FM7A@200643|Bacteroidia,4AKW7@815|Bacteroidaceae	976|Bacteroidetes	H	riboflavin biosynthesis protein	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HSJS3_k127_1349952_1	243090.RB12783	0.0004015	52.0	COG2165@1|root,COG2165@2|Bacteria,2J14K@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HSJS3_k127_1349952_0	575540.Isop_3022	4.134e-07	59.0	COG4968@1|root,COG4968@2|Bacteria,2J3MJ@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
HSJS3_k127_1359654_0	751944.HALDL1_08215	5.784e-45	174.0	COG1058@1|root,arCOG00215@2157|Archaea,2XUAN@28890|Euryarchaeota,23S6F@183963|Halobacteria	183963|Halobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	cinA1	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
HSJS3_k127_1359654_2	930169.B5T_03100	1.898e-05	55.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1XM17@135619|Oceanospirillales	135619|Oceanospirillales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HSJS3_k127_1359654_1	1123376.AUIU01000011_gene1012	6.547e-14	76.0	COG0617@1|root,COG0617@2|Bacteria	2|Bacteria	J	CTP:tRNA cytidylyltransferase activity	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974,ko:K07276,ko:K19545	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko01504,ko03016,ko03019	-	-	-	Aminoglyc_resit,HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HSJS3_k127_1366785_1	448385.sce6437	2.816e-39	157.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,42WBG@68525|delta/epsilon subdivisions,2WS3Q@28221|Deltaproteobacteria,2YY0X@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
HSJS3_k127_1366785_2	278963.ATWD01000001_gene1577	1.184e-15	81.0	COG1695@1|root,COG1695@2|Bacteria,3Y873@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_1366785_0	521098.Aaci_2944	4.579e-61	222.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,277VE@186823|Alicyclobacillaceae	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HSJS3_k127_1382520_0	591001.Acfer_1475	8.031e-55	202.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4H217@909932|Negativicutes	909932|Negativicutes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS3_k127_1382520_1	324831.LGAS_1742	1.258e-28	117.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F4AE@33958|Lactobacillaceae	91061|Bacilli	D	Sporulation initiation inhibitor	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HSJS3_k127_139221_4	997346.HMPREF9374_2906	7.277e-27	118.0	COG0500@1|root,COG0500@2|Bacteria,1V1KE@1239|Firmicutes	1239|Firmicutes	Q	Methyltransferase	tehB	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	DUF1971,Methyltransf_25,TehB
HSJS3_k127_139221_8	1120949.KB903297_gene5604	4.886e-05	53.0	COG3170@1|root,COG3170@2|Bacteria,2GT0Z@201174|Actinobacteria,4DFUJ@85008|Micromonosporales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_139221_7	1380386.JIAW01000005_gene1436	3.229e-06	59.0	COG3832@1|root,COG3832@2|Bacteria,2GRHS@201174|Actinobacteria,239EG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS3_k127_139221_6	398767.Glov_0699	5.775e-14	83.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,43B2E@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	peptidyl-prolyl isomerase	peb4	-	5.2.1.8	ko:K01802,ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
HSJS3_k127_139221_1	717605.Theco_2187	9.544e-78	275.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HSJS3_k127_139221_3	500635.MITSMUL_03763	1.803e-46	174.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4H3ZW@909932|Negativicutes	909932|Negativicutes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HSJS3_k127_139221_5	717605.Theco_0816	4.177e-18	89.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,26ZFK@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
HSJS3_k127_139221_2	649639.Bcell_0416	7.999e-66	232.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,1ZAWJ@1386|Bacillus	91061|Bacilli	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HSJS3_k127_139221_0	706587.Desti_1449	1.007e-122	411.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2MREF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HSJS3_k127_1395200_1	459349.CLOAM1805	3.485e-21	97.0	COG1478@1|root,COG1478@2|Bacteria	2|Bacteria	S	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	F420_ligase
HSJS3_k127_1395200_0	452637.Oter_1299	3.715e-72	254.0	COG0039@1|root,COG0039@2|Bacteria,46T5I@74201|Verrucomicrobia,3K79S@414999|Opitutae	414999|Opitutae	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HSJS3_k127_1395200_2	1140.Synpcc7942_0932	1.061e-20	96.0	COG0763@1|root,COG0763@2|Bacteria,1G0V6@1117|Cyanobacteria,1GYVI@1129|Synechococcus	1117|Cyanobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HSJS3_k127_1396632_2	1123392.AQWL01000005_gene3147	1.03e-64	238.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,1KSVJ@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_1396632_1	909663.KI867150_gene1574	7.445e-76	269.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2MQ7C@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_1396632_4	289377.HL41_03190	2.313e-27	128.0	COG0845@1|root,COG0845@2|Bacteria,2GGXV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
HSJS3_k127_1396632_5	1121870.AUAA01000003_gene2554	2.211e-17	86.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1I3YF@117743|Flavobacteriia,3HIC9@358033|Chryseobacterium	976|Bacteroidetes	O	NifU-like domain	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
HSJS3_k127_1396632_6	1356854.N007_15035	1.907e-16	89.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,27845@186823|Alicyclobacillaceae	91061|Bacilli	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HSJS3_k127_1396632_7	1394178.AWOO02000033_gene8475	1.877e-06	58.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,4EJT0@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HSJS3_k127_1396632_3	670487.Ocepr_2208	3.155e-46	178.0	COG0682@1|root,COG0682@2|Bacteria,1WJCB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HSJS3_k127_1396632_0	635013.TherJR_1277	3.033e-144	466.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,260U5@186807|Peptococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HSJS3_k127_1396632_8	633147.Olsu_0957	9.5e-06	55.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4CURU@84998|Coriobacteriia	84998|Coriobacteriia	NU	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HSJS3_k127_1397426_0	246194.CHY_1919	2.107e-93	327.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,42F2X@68295|Thermoanaerobacterales	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HSJS3_k127_1398851_4	999423.HMPREF9161_00292	2.181e-24	105.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4H2MP@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HSJS3_k127_1398851_3	383372.Rcas_0024	2.112e-24	112.0	COG1595@1|root,COG1595@2|Bacteria,2GBQ7@200795|Chloroflexi,376YC@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_1398851_0	1158345.JNLL01000001_gene98	1.011e-172	555.0	COG0499@1|root,COG0499@2|Bacteria,2G3TI@200783|Aquificae	200783|Aquificae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
HSJS3_k127_1398851_2	592028.GCWU000321_00399	7.115e-57	224.0	COG3064@1|root,COG3064@2|Bacteria,1U2T9@1239|Firmicutes,4H255@909932|Negativicutes	909932|Negativicutes	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
HSJS3_k127_1398851_1	1384054.N790_14285	2.331e-66	235.0	COG1222@1|root,COG1222@2|Bacteria,1QVRV@1224|Proteobacteria,1SJQT@1236|Gammaproteobacteria,1X9QK@135614|Xanthomonadales	135614|Xanthomonadales	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
HSJS3_k127_1408476_0	1444309.JAQG01000099_gene4971	1.407e-168	543.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,26SJC@186822|Paenibacillaceae	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HSJS3_k127_1408476_1	411490.ANACAC_02462	1.555e-10	70.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia	186801|Clostridia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
HSJS3_k127_1408476_2	1206777.B195_21070	3.897e-08	62.0	COG0526@1|root,COG0526@2|Bacteria,1RJUZ@1224|Proteobacteria,1SYYB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Prolipoprotein diacylglyceryl transferase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,LGT,Redoxin
HSJS3_k127_1486351_1	666510.ASAC_1438	7.521e-30	128.0	COG1577@1|root,arCOG01028@2157|Archaea,2XQ8U@28889|Crenarchaeota	28889|Crenarchaeota	F	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HSJS3_k127_1486351_0	1449337.JQLL01000001_gene1999	9.791e-55	205.0	COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,27FWI@186828|Carnobacteriaceae	91061|Bacilli	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HSJS3_k127_1486351_2	502025.Hoch_3407	2.146e-05	55.0	COG1577@1|root,COG1577@2|Bacteria,1N400@1224|Proteobacteria	1224|Proteobacteria	I	GHMP kinases N terminal domain	-	-	2.7.4.2	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R03245	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
HSJS3_k127_1494184_0	479434.Sthe_2363	1.185e-280	871.0	COG0209@1|root,COG0209@2|Bacteria,2G8RN@200795|Chloroflexi,27Y2V@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
HSJS3_k127_1503363_3	937777.Deipe_3103	4.449e-21	94.0	COG1494@1|root,COG1494@2|Bacteria,1WI3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
HSJS3_k127_1503363_1	945713.IALB_0211	1.246e-105	351.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HSJS3_k127_1503363_2	589924.Ferp_2133	5.021e-101	356.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,245T6@183980|Archaeoglobi	183980|Archaeoglobi	J	phenylalanyl-tRNA synthetase, beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
HSJS3_k127_1503363_0	477641.MODMU_1128	1.887e-136	449.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4ERBS@85013|Frankiales	201174|Actinobacteria	S	peptidase U62, modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
HSJS3_k127_1507353_1	491952.Mar181_1164	1.274e-19	95.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS3_k127_1507353_2	216596.RL2271	2.308e-07	58.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2UAEV@28211|Alphaproteobacteria,4BFF4@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
HSJS3_k127_1507353_0	926550.CLDAP_27410	8.591e-70	246.0	COG1131@1|root,COG1131@2|Bacteria,2G6KA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_1510011_2	765698.Mesci_2215	5.005e-17	82.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,2UC19@28211|Alphaproteobacteria,43K6R@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HSJS3_k127_1510011_0	1297570.MESS4_800010	7.703e-46	174.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2U986@28211|Alphaproteobacteria,43JYJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
HSJS3_k127_1510011_1	234267.Acid_7234	1.711e-17	97.0	COG0457@1|root,COG0457@2|Bacteria,3Y5ID@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1520793_2	765910.MARPU_15725	3.421e-56	204.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1WVY3@135613|Chromatiales	135613|Chromatiales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_1520793_6	1379698.RBG1_1C00001G0126	9.663e-09	65.0	2C451@1|root,2ZRAU@2|Bacteria,2NS2X@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1520793_4	113355.CM001775_gene3878	7.527e-28	118.0	COG1943@1|root,COG1943@2|Bacteria,1G5Z6@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HSJS3_k127_1520793_7	1280947.HY30_03290	5.528e-06	60.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2U0VY@28211|Alphaproteobacteria,43ZCS@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	-	-	Autotransporter,Peptidase_S8
HSJS3_k127_1520793_0	886293.Sinac_2992	1.746e-68	237.0	COG0302@1|root,COG0302@2|Bacteria,2IYUA@203682|Planctomycetes	203682|Planctomycetes	H	PFAM GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HSJS3_k127_1520793_1	868864.Dester_0390	1.07e-67	243.0	COG0294@1|root,COG0294@2|Bacteria,2G3IT@200783|Aquificae	200783|Aquificae	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HSJS3_k127_1520793_3	706587.Desti_0814	2.232e-31	128.0	COG1943@1|root,COG1943@2|Bacteria,1PDK8@1224|Proteobacteria,430IV@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HSJS3_k127_1520793_5	999411.HMPREF1092_02910	4.445e-11	66.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,24A3T@186801|Clostridia,36E7Y@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
HSJS3_k127_15220_0	1270196.JCKI01000005_gene3072	4.407e-140	455.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_15220_3	1122237.AUGQ01000017_gene2445	9.816e-05	56.0	COG1404@1|root,COG2133@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4FR98@85023|Microbacteriaceae	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,CBM_6,GSDH,PKD
HSJS3_k127_15220_2	509635.N824_26405	7.085e-06	55.0	2BWZA@1|root,32RGQ@2|Bacteria,4NQBI@976|Bacteroidetes,1ITP6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_15220_1	1304885.AUEY01000150_gene651	4.731e-39	160.0	COG3291@1|root,COG3291@2|Bacteria,1NM1Z@1224|Proteobacteria,42XEW@68525|delta/epsilon subdivisions,2WSVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1544210_1	1499968.TCA2_1803	1.702e-05	57.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26SE7@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	prtS	-	3.4.21.110,3.4.21.96	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5
HSJS3_k127_1544210_0	234267.Acid_0291	2.77e-83	295.0	COG1167@1|root,COG1167@2|Bacteria,3Y4RE@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
HSJS3_k127_1579822_5	794903.OPIT5_17385	1.673e-05	56.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
HSJS3_k127_1579822_4	309799.DICTH_0725	1.95e-06	59.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
HSJS3_k127_1579822_6	1324957.K933_16512	0.0002068	57.0	COG3291@1|root,arCOG07560@1|root,arCOG07781@1|root,arCOG10187@1|root,arCOG02546@2157|Archaea,arCOG07560@2157|Archaea,arCOG07781@2157|Archaea,arCOG10187@2157|Archaea,2XYYY@28890|Euryarchaeota,23X3J@183963|Halobacteria	183963|Halobacteria	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PKD
HSJS3_k127_1579822_2	1392502.JNIO01000008_gene2766	5.542e-18	100.0	COG4796@1|root,COG4796@2|Bacteria,1UK31@1239|Firmicutes,4H2BW@909932|Negativicutes	909932|Negativicutes	U	type II and III secretion system protein	pilQ	-	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin,Secretin_N
HSJS3_k127_1579822_1	1168065.DOK_00572	5.5e-21	108.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1J4VC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG4972 Tfp pilus assembly protein, ATPase PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
HSJS3_k127_1579822_7	533247.CRD_01822	0.0005962	53.0	COG3166@1|root,COG3166@2|Bacteria,1G5IC@1117|Cyanobacteria,1HKBQ@1161|Nostocales	1117|Cyanobacteria	NU	PFAM Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
HSJS3_k127_1579822_0	1500257.JQNM01000011_gene5654	1.089e-69	257.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,4BABT@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HSJS3_k127_1579822_3	445335.CBN_3145	4.433e-14	86.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,36ERI@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
HSJS3_k127_1603379_2	190650.CC_1678	2.804e-79	277.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria,2KFB0@204458|Caulobacterales	204458|Caulobacterales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HSJS3_k127_1603379_4	471223.GWCH70_1081	1.054e-60	218.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1WEUB@129337|Geobacillus	91061|Bacilli	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
HSJS3_k127_1603379_1	1297742.A176_02927	2.081e-80	279.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,2YU16@29|Myxococcales	28221|Deltaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HSJS3_k127_1603379_0	382464.ABSI01000010_gene3377	1.737e-95	323.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HSJS3_k127_1603379_3	338963.Pcar_1435	5.702e-65	239.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria,43T0B@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HSJS3_k127_1603379_7	448385.sce4295	1.4e-13	83.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CarboxypepD_reg,HemolysinCabind
HSJS3_k127_1603379_5	526222.Desal_1481	1.594e-60	230.0	COG1305@1|root,COG1305@2|Bacteria,1NS1B@1224|Proteobacteria,42Z4Y@68525|delta/epsilon subdivisions,2WUP9@28221|Deltaproteobacteria,2MAAZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HSJS3_k127_1603379_6	525897.Dbac_1605	3.342e-17	88.0	COG0357@1|root,COG0357@2|Bacteria,1Q2S1@1224|Proteobacteria,42SV8@68525|delta/epsilon subdivisions,2WP78@28221|Deltaproteobacteria,2MAK5@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HSJS3_k127_1604200_9	413816.BBJP01000004_gene240	7.971e-06	50.0	arCOG08936@1|root,arCOG08936@2157|Archaea,2XYCQ@28890|Euryarchaeota,23WHK@183963|Halobacteria	183963|Halobacteria	M	Intracellular proteinase inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI
HSJS3_k127_1604200_7	2325.TKV_c07300	6.727e-38	153.0	28NMK@1|root,2ZBN3@2|Bacteria,1TT4K@1239|Firmicutes,24EKK@186801|Clostridia,42FUC@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	amj	-	-	-	-	-	-	-	-	-	-	-	Amj
HSJS3_k127_1604200_0	401526.TcarDRAFT_1341	2.904e-87	299.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1TQ04@1239|Firmicutes,4H28I@909932|Negativicutes	909932|Negativicutes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
HSJS3_k127_1604200_1	1120985.AUMI01000015_gene1532	1.036e-66	237.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4H32V@909932|Negativicutes	909932|Negativicutes	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HSJS3_k127_1604200_6	338966.Ppro_0982	5.722e-38	154.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HSJS3_k127_1604200_4	1094980.Mpsy_0800	8.712e-52	188.0	COG1432@1|root,arCOG02408@2157|Archaea,2XUXP@28890|Euryarchaeota	28890|Euryarchaeota	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
HSJS3_k127_1604200_2	1453501.JELR01000002_gene1368	2.247e-58	221.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,465J7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HSJS3_k127_1604200_5	1089553.Tph_c06550	3.176e-51	198.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42FSF@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HSJS3_k127_1604200_8	401526.TcarDRAFT_0543	4.864e-35	146.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HSJS3_k127_1604200_3	1381751.JAJB01000106_gene2904	1.146e-54	196.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4F92V@85019|Brevibacteriaceae	201174|Actinobacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HSJS3_k127_1615395_0	391626.OAN307_c06760	1.263e-08	64.0	COG3324@1|root,COG3324@2|Bacteria,1NB88@1224|Proteobacteria,2UBWV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
HSJS3_k127_1615395_2	114615.BRADO2928	7.086e-07	58.0	COG3832@1|root,COG3832@2|Bacteria,1RAW4@1224|Proteobacteria,2UI5Z@28211|Alphaproteobacteria,3JYIZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS3_k127_1615395_1	471852.Tcur_2800	3.037e-08	61.0	COG2329@1|root,COG3832@1|root,COG2329@2|Bacteria,COG3832@2|Bacteria,2HUAP@201174|Actinobacteria,4EPGB@85012|Streptosporangiales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HSJS3_k127_1622895_1	586416.GZ22_01715	0.0006272	49.0	COG3339@1|root,COG3339@2|Bacteria,1VFBU@1239|Firmicutes,4HPPR@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HSJS3_k127_1622895_0	436114.SYO3AOP1_0864	4.83e-48	179.0	COG0223@1|root,COG0223@2|Bacteria,2G3PD@200783|Aquificae	200783|Aquificae	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HSJS3_k127_1626967_0	880073.Calab_0186	6.639e-56	207.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HSJS3_k127_1626967_1	497964.CfE428DRAFT_0914	8.635e-46	174.0	COG0745@1|root,COG0745@2|Bacteria	497964.CfE428DRAFT_0914|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1630802_0	565033.GACE_1720	8.289e-35	148.0	COG1614@1|root,arCOG04360@2157|Archaea,2XTDX@28890|Euryarchaeota,2461C@183980|Archaeoglobi	183980|Archaeoglobi	C	Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex)	-	-	-	ko:K00193	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00357,M00422	R09096,R10219	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HSJS3_k127_1630802_1	2423.NA23_0202575	4.018e-17	91.0	COG0697@1|root,COG0697@2|Bacteria,2GCQS@200918|Thermotogae	200918|Thermotogae	EG	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
HSJS3_k127_166185_8	1122599.AUGR01000027_gene1270	2.515e-06	51.0	2AWWV@1|root,31NUD@2|Bacteria,1QPF3@1224|Proteobacteria,1SJ55@1236|Gammaproteobacteria,1XQNS@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_166185_9	1410668.JNKC01000016_gene993	0.0007844	42.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_166185_0	1121448.DGI_1765	1.54e-197	621.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2M88A@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HSJS3_k127_166185_7	1123373.ATXI01000007_gene1664	5.159e-13	70.0	COG0267@1|root,COG0267@2|Bacteria,2GI3K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HSJS3_k127_166185_4	350688.Clos_0479	1.545e-39	153.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,36F5J@31979|Clostridiaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HSJS3_k127_166185_2	1121364.ATVG01000010_gene1821	1.182e-53	193.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,22MWG@1653|Corynebacteriaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HSJS3_k127_166185_1	635013.TherJR_0284	1.635e-72	252.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,260G7@186807|Peptococcaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HSJS3_k127_166185_6	234267.Acid_5459	5.109e-14	78.0	COG0244@1|root,COG0244@2|Bacteria,3Y4N2@57723|Acidobacteria	57723|Acidobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HSJS3_k127_166185_5	1122216.AUHW01000005_gene455	8.412e-33	132.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes	909932|Negativicutes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HSJS3_k127_166185_3	1032480.MLP_10750	2.421e-47	187.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4DMYN@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HSJS3_k127_1666835_0	864069.MicloDRAFT_00023580	3.165e-69	238.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,1JUR8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HSJS3_k127_1666835_1	1449058.JQKT01000007_gene1661	1.7e-26	116.0	28XTZ@1|root,2ZJQD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_1676060_3	1128421.JAGA01000004_gene2692	4.025e-09	60.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HSJS3_k127_1676060_1	639030.JHVA01000001_gene3757	5.225e-38	161.0	COG1749@1|root,COG2372@1|root,COG4257@1|root,COG4932@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG4257@2|Bacteria,COG4932@2|Bacteria,3Y930@57723|Acidobacteria	57723|Acidobacteria	M	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082
HSJS3_k127_1676060_2	549.BW31_03690	2.24e-18	87.0	COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,1SHYR@1236|Gammaproteobacteria,3W2S8@53335|Pantoea	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
HSJS3_k127_1676060_0	1178537.BA1_05027	1.316e-84	308.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	sftA	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Ftsk_gamma
HSJS3_k127_1698700_1	700598.Niako_6249	4.312e-28	121.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1IQR6@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HSJS3_k127_1698700_0	885272.JonanDRAFT_1141	4.017e-100	338.0	COG4608@1|root,COG4608@2|Bacteria,3TANU@508458|Synergistetes	508458|Synergistetes	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
HSJS3_k127_1708799_1	767817.Desgi_2109	4.222e-51	190.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
HSJS3_k127_1708799_0	644282.Deba_2879	6.403e-122	404.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
HSJS3_k127_1764147_1	1379270.AUXF01000001_gene2485	8.982e-28	116.0	COG0735@1|root,COG0735@2|Bacteria,1ZUXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS3_k127_1764147_2	926559.JoomaDRAFT_2192	8.989e-27	116.0	COG0526@1|root,COG0526@2|Bacteria,4NNU2@976|Bacteroidetes,1I22P@117743|Flavobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_1764147_0	1042377.AFPJ01000020_gene2059	3.525e-111	379.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8
HSJS3_k127_1785603_0	759914.BP951000_2231	1.234e-122	405.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2J5C7@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Asn_synthase,GATase,GMP_synt_C,NAD_synthase
HSJS3_k127_1785603_1	269799.Gmet_0751	7.239e-08	62.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
HSJS3_k127_1802621_3	526227.Mesil_0293	6.814e-10	60.0	COG1902@1|root,COG1902@2|Bacteria,1WIIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HSJS3_k127_1802621_4	491205.JARQ01000007_gene3106	1.875e-08	64.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia,3ZRZ8@59732|Chryseobacterium	976|Bacteroidetes	E	Glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS3_k127_1802621_2	1033734.CAET01000075_gene2765	5.111e-14	81.0	COG0346@1|root,COG0346@2|Bacteria,1V93D@1239|Firmicutes,4HI94@91061|Bacilli,1ZGC0@1386|Bacillus	91061|Bacilli	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS3_k127_1802621_0	767817.Desgi_1785	2.599e-274	857.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia,260G2@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HSJS3_k127_1802621_1	1944.JOAZ01000001_gene4132	1.348e-72	260.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,41956@629295|Streptomyces griseus group	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_1819398_1	484770.UFO1_3708	1.724e-45	176.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_1819398_0	1254432.SCE1572_28745	2.544e-49	191.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_1819398_2	562970.Btus_1426	4.599e-23	115.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HSJS3_k127_18408_0	1131269.AQVV01000002_gene1215	7.137e-160	527.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	fadF	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
HSJS3_k127_18408_1	913325.N799_05555	3.798e-12	78.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1X486@135614|Xanthomonadales	135614|Xanthomonadales	I	3-hydroxyacyl-coa dehydrogenase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HSJS3_k127_1845725_3	768671.ThimaDRAFT_1889	5.755e-64	227.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1S3AX@1236|Gammaproteobacteria,1X2H3@135613|Chromatiales	135613|Chromatiales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HSJS3_k127_1845725_2	706587.Desti_1132	3.222e-68	243.0	COG0715@1|root,COG0715@2|Bacteria,1R5H3@1224|Proteobacteria,42M2N@68525|delta/epsilon subdivisions,2WPCV@28221|Deltaproteobacteria,2MRI0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
HSJS3_k127_1845725_4	373903.Hore_14760	2.632e-55	202.0	COG1116@1|root,COG1116@2|Bacteria,1TT4F@1239|Firmicutes,24FTR@186801|Clostridia,3WBPS@53433|Halanaerobiales	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HSJS3_k127_1845725_1	706587.Desti_1134	2.822e-69	243.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,42NMC@68525|delta/epsilon subdivisions,2WMA8@28221|Deltaproteobacteria,2MQUS@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HSJS3_k127_1845725_0	706587.Desti_1136	1.232e-77	270.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S34@68525|delta/epsilon subdivisions,2WNRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HSJS3_k127_1845725_5	944480.ATUV01000001_gene1070	3.161e-26	109.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2WM6R@28221|Deltaproteobacteria,2M6XC@213113|Desulfurellales	28221|Deltaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HSJS3_k127_1902914_1	1201290.M902_2441	5.589e-15	76.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2MT22@213481|Bdellovibrionales,2WJPD@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS3_k127_1902914_0	1121861.KB899919_gene2748	7.243e-66	238.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JPVE@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg
HSJS3_k127_1906880_1	1123008.KB905696_gene2918	2.99e-65	236.0	COG1409@1|root,COG1409@2|Bacteria,4NEQ8@976|Bacteroidetes,2FNYC@200643|Bacteroidia,22XK6@171551|Porphyromonadaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HSJS3_k127_1906880_2	595460.RRSWK_00745	7.499e-54	203.0	COG0577@1|root,COG0577@2|Bacteria,2IZAQ@203682|Planctomycetes	203682|Planctomycetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HSJS3_k127_1906880_4	313628.LNTAR_08086	3.36e-36	151.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_1906880_0	530564.Psta_1226	1.532e-72	251.0	COG1136@1|root,COG1136@2|Bacteria,2IYT0@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_1906880_6	1123508.JH636442_gene4296	5.707e-13	81.0	COG0845@1|root,COG0845@2|Bacteria,2IYR9@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
HSJS3_k127_1906880_5	1162668.LFE_1242	9.327e-26	113.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_24
HSJS3_k127_1906880_3	439235.Dalk_5032	1.429e-44	166.0	COG0735@1|root,COG0735@2|Bacteria,1Q2NI@1224|Proteobacteria,42SV3@68525|delta/epsilon subdivisions,2WPH8@28221|Deltaproteobacteria,2MKA3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS3_k127_1945577_0	1303518.CCALI_00828	2.395e-105	350.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HSJS3_k127_2028111_0	869210.Marky_1162	1.583e-136	448.0	COG4992@1|root,COG4992@2|Bacteria,1WIII@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.13,2.6.1.82	ko:K00819,ko:K09251	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667,R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HSJS3_k127_2028111_3	1036674.A28LD_1935	5.103e-40	154.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,2QG16@267893|Idiomarinaceae	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HSJS3_k127_2028111_1	103690.17132557	1.044e-57	213.0	COG1089@1|root,COG1089@2|Bacteria,1G2EQ@1117|Cyanobacteria,1HRH8@1161|Nostocales	1117|Cyanobacteria	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HSJS3_k127_2028111_2	1191523.MROS_0441	7.861e-48	177.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS3_k127_2073179_2	768670.Calni_1098	1.718e-08	57.0	COG0325@1|root,COG0325@2|Bacteria,2GFHY@200930|Deferribacteres	200930|Deferribacteres	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HSJS3_k127_2073179_1	264732.Moth_0859	7.614e-10	65.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HSJS3_k127_2073179_0	944564.HMPREF9200_0908	2.664e-98	331.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4H1Y7@909932|Negativicutes	909932|Negativicutes	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HSJS3_k127_207725_0	118005.AWNK01000006_gene1381	1.412e-109	367.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	pitA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HSJS3_k127_207725_3	1047013.AQSP01000139_gene2337	1.506e-32	135.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	CP_0066	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HSJS3_k127_207725_1	690850.Desaf_0151	2.607e-36	144.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,42RXK@68525|delta/epsilon subdivisions,2WNRW@28221|Deltaproteobacteria,2M8EY@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HSJS3_k127_207725_2	1227360.C176_04288	1.531e-34	140.0	COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,26DIB@186818|Planococcaceae	91061|Bacilli	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
HSJS3_k127_207725_4	3075.A0A087SRH5	4.147e-07	56.0	COG0457@1|root,KOG1126@2759|Eukaryota,37KQ2@33090|Viridiplantae,34K1D@3041|Chlorophyta	3041|Chlorophyta	D	Tetratricopeptide repeat	APC3	-	-	ko:K03350	ko04110,ko04111,ko04113,ko04114,ko04120,ko04914,ko05166,map04110,map04111,map04113,map04114,map04120,map04914,map05166	M00389	-	-	ko00000,ko00001,ko00002,ko01009,ko03036,ko04121	-	-	-	ANAPC3,TPR_1,TPR_11,TPR_16,TPR_8
HSJS3_k127_2107309_5	1232410.KI421424_gene1783	7.154e-10	62.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,43TBR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
HSJS3_k127_2107309_6	604331.AUHY01000009_gene376	2.471e-08	63.0	COG0852@1|root,COG0852@2|Bacteria,1WIWA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HSJS3_k127_2107309_3	1267534.KB906754_gene3160	2.754e-23	103.0	2EE2W@1|root,337XH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2107309_0	1380390.JIAT01000001_gene5106	7.533e-85	290.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Methyltransf_31
HSJS3_k127_2107309_1	864563.HMPREF9166_0972	3.692e-41	158.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,4H438@909932|Negativicutes	909932|Negativicutes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HSJS3_k127_2107309_4	575540.Isop_0670	1.624e-10	67.0	COG0838@1|root,COG0838@2|Bacteria,2J09T@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HSJS3_k127_2107309_2	416348.Hlac_2824	8.782e-41	173.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
HSJS3_k127_214011_2	1395587.P364_0129145	4.394e-61	218.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HSJS3_k127_214011_1	1303518.CCALI_00718	2.76e-66	235.0	COG0157@1|root,COG0157@2|Bacteria	2|Bacteria	H	quinolinate catabolic process	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988,iHN637.CLJU_RS12010,iLJ478.TM1645	QRPTase_C,QRPTase_N
HSJS3_k127_214011_3	316274.Haur_1635	1.719e-15	81.0	COG1555@1|root,COG1555@2|Bacteria,2G771@200795|Chloroflexi,377EV@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat protein	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HSJS3_k127_214011_0	1379698.RBG1_1C00001G1510	1.427e-76	273.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
HSJS3_k127_2334158_0	1380763.BG53_15830	0.000488	51.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HGZ2@91061|Bacilli,26SJY@186822|Paenibacillaceae	91061|Bacilli	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HSJS3_k127_235009_1	321332.CYB_1764	2.836e-10	72.0	COG4372@1|root,COG4372@2|Bacteria,1G0XA@1117|Cyanobacteria,1GZ66@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF3084)	sll1424	-	-	-	-	-	-	-	-	-	-	-	DUF3084
HSJS3_k127_235009_0	796606.BMMGA3_05270	1.081e-14	86.0	COG3206@1|root,COG3206@2|Bacteria,1V8AX@1239|Firmicutes,4HCT2@91061|Bacilli,1ZDP1@1386|Bacillus	91061|Bacilli	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
HSJS3_k127_2481349_4	768710.DesyoDRAFT_4333	9.847e-26	119.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,2610Z@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS3_k127_2481349_5	357808.RoseRS_2119	7.013e-25	118.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi,3768V@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_2481349_1	1173029.JH980292_gene83	1.117e-35	150.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_2481349_2	471853.Bcav_3234	3.054e-31	138.0	COG0265@1|root,COG3115@1|root,COG0265@2|Bacteria,COG3115@2|Bacteria,2GJ96@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	degP	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_2481349_3	868864.Dester_0544	2.706e-26	122.0	COG0265@1|root,COG0265@2|Bacteria,2G3MU@200783|Aquificae	200783|Aquificae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_2481349_0	1121904.ARBP01000002_gene7225	4.786e-80	276.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,47JTQ@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HSJS3_k127_2687087_2	698758.AXY_00910	9.947e-17	81.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HSJS3_k127_2687087_3	1121033.AUCF01000006_gene4273	1.982e-07	60.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,2JQ4S@204441|Rhodospirillales	204441|Rhodospirillales	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
HSJS3_k127_2687087_1	1380390.JIAT01000001_gene5042	3.751e-17	89.0	COG5607@1|root,COG5607@2|Bacteria,2HP53@201174|Actinobacteria,4CQGX@84995|Rubrobacteria	84995|Rubrobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
HSJS3_k127_2687087_0	443143.GM18_1550	1.352e-36	151.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,43UE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	FP	metal-dependent phosphohydrolase, HD sub domain	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
HSJS3_k127_2687087_4	675806.VII_003474	0.0001799	49.0	COG4775@1|root,COG4775@2|Bacteria,1MX3H@1224|Proteobacteria,1RQKV@1236|Gammaproteobacteria,1XSM5@135623|Vibrionales	135623|Vibrionales	M	Exopolysaccharide biosynthesis protein YbjH	wbfB	-	-	-	-	-	-	-	-	-	-	-	YjbH
HSJS3_k127_2700192_0	1454004.AW11_02812	1.48e-53	207.0	COG2010@1|root,COG2010@2|Bacteria,1RDNN@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
HSJS3_k127_2700532_2	630626.EBL_c18490	6.983e-37	142.0	COG0411@1|root,COG0411@2|Bacteria,1QUC5@1224|Proteobacteria,1T1SR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
HSJS3_k127_2700532_1	1220589.CD32_05300	8.396e-55	209.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,3IVZV@400634|Lysinibacillus	91061|Bacilli	U	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HSJS3_k127_2700532_0	562970.Btus_1711	2.55e-64	239.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,277YM@186823|Alicyclobacillaceae	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HSJS3_k127_2700532_3	1395587.P364_0106205	7.957e-18	85.0	COG1011@1|root,COG1011@2|Bacteria,1TPBK@1239|Firmicutes,4I3FM@91061|Bacilli,26XBT@186822|Paenibacillaceae	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HSJS3_k127_2700679_0	56780.SYN_02537	5.796e-109	377.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MQD2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HSJS3_k127_2700679_1	358396.C445_15631	8.091e-72	253.0	COG2746@1|root,arCOG06298@2157|Archaea,2XSY6@28890|Euryarchaeota,23TW3@183963|Halobacteria	183963|Halobacteria	V	COG2746 Aminoglycoside N3'-acetyltransferase	aacC	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
HSJS3_k127_2700679_2	1042877.GQS_00525	3.664e-12	74.0	COG5016@1|root,arCOG02095@2157|Archaea,2XV3W@28890|Euryarchaeota,243F6@183968|Thermococci	183968|Thermococci	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
HSJS3_k127_2705441_1	66429.JOFL01000001_gene4411	4.241e-40	154.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	MA20_24580	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HSJS3_k127_2705441_0	861450.HMPREF0080_00483	1.024e-41	161.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HSJS3_k127_2722867_0	1380390.JIAT01000009_gene906	1.718e-08	68.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
HSJS3_k127_2741210_0	697281.Mahau_0283	6.482e-183	584.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42F5B@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HSJS3_k127_2741210_1	1122135.KB893167_gene2313	1.767e-165	530.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HSJS3_k127_2741210_4	309801.trd_A0408	4.183e-30	124.0	COG0717@1|root,COG0717@2|Bacteria,2G8PG@200795|Chloroflexi,27YDB@189775|Thermomicrobia	189775|Thermomicrobia	F	dUTPase	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HSJS3_k127_2741210_3	1120972.AUMH01000015_gene1287	1.56e-35	143.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,279WU@186823|Alicyclobacillaceae	91061|Bacilli	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HSJS3_k127_2741210_2	926550.CLDAP_20370	1.745e-129	426.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
HSJS3_k127_2741210_5	935866.JAER01000002_gene1875	2.263e-27	114.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4DRMD@85009|Propionibacteriales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
HSJS3_k127_2741210_6	469383.Cwoe_5393	5.759e-15	76.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HSJS3_k127_2745832_0	485916.Dtox_3956	3.365e-124	409.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HSJS3_k127_2745832_1	765420.OSCT_1067	2.96e-16	87.0	COG1695@1|root,COG1695@2|Bacteria,2G99R@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HSJS3_k127_2745832_2	293826.Amet_2801	1.451e-05	55.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,36IWC@31979|Clostridiaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
HSJS3_k127_2767456_0	1068980.ARVW01000001_gene5379	1.956e-44	172.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS3_k127_2768722_2	242619.PG_2109	8.545e-05	51.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,4NNFB@976|Bacteroidetes,2FMPB@200643|Bacteroidia,22X6W@171551|Porphyromonadaceae	976|Bacteroidetes	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
HSJS3_k127_2768722_1	1121373.KB903623_gene2288	8.068e-20	102.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HSJS3_k127_2768722_0	1382306.JNIM01000001_gene649	1.806e-33	143.0	COG0859@1|root,COG0859@2|Bacteria,2G8MX@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
HSJS3_k127_2815726_0	765912.Thimo_1752	6.099e-28	130.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1RZ6G@1236|Gammaproteobacteria,1X1H2@135613|Chromatiales	135613|Chromatiales	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HSJS3_k127_2817838_1	945713.IALB_3128	7.916e-12	74.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
HSJS3_k127_2817838_2	7739.XP_002613810.1	4.65e-07	63.0	2C8EZ@1|root,2QQUS@2759|Eukaryota,38DKV@33154|Opisthokonta,3BB2X@33208|Metazoa,3D1H3@33213|Bilateria,48AZI@7711|Chordata	33208|Metazoa	S	Peptidase M60-like family	FAM115C	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010359,GO:0010360,GO:0016020,GO:0022898,GO:0030054,GO:0030334,GO:0030335,GO:0032386,GO:0032388,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0032880,GO:0033157,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040012,GO:0040017,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044325,GO:0044464,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0051049,GO:0051050,GO:0051051,GO:0051222,GO:0051223,GO:0051270,GO:0051272,GO:0060341,GO:0065007,GO:0065009,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:0090314,GO:0090316,GO:1903533,GO:1903792,GO:1903827,GO:1903829,GO:1903959,GO:1903960,GO:1904951,GO:1905475,GO:1905477,GO:2000145,GO:2000147	-	-	-	-	-	-	-	-	-	-	M60-like_N,Peptidase_M60
HSJS3_k127_2817838_3	118161.KB235922_gene3646	0.0003673	53.0	COG0823@1|root,COG4249@1|root,COG0823@2|Bacteria,COG4249@2|Bacteria,1GQ28@1117|Cyanobacteria	1117|Cyanobacteria	U	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
HSJS3_k127_2817838_0	1232410.KI421418_gene2444	2.497e-77	271.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,43T78@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HSJS3_k127_2821707_2	309801.trd_0088	1.915e-13	79.0	COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi,27XJ4@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_2821707_1	1007096.BAGW01000025_gene1472	9.581e-31	138.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,2N6XC@216572|Oscillospiraceae	186801|Clostridia	L	Calcineurin-like phosphoesterase	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
HSJS3_k127_2821707_4	445971.ANASTE_01136	2.378e-06	61.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,25EBC@186801|Clostridia,25ZKF@186806|Eubacteriaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
HSJS3_k127_2821707_0	1121472.AQWN01000002_gene2108	4.685e-78	282.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
HSJS3_k127_2821707_3	1122927.KB895418_gene2874	1.93e-10	66.0	COG1595@1|root,COG1595@2|Bacteria,1VIG7@1239|Firmicutes,4HTNK@91061|Bacilli,26U1D@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_2821727_0	1499967.BAYZ01000173_gene5813	6.005e-62	231.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
HSJS3_k127_284186_3	266940.Krad_3225	3.762e-42	163.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria	201174|Actinobacteria	Q	phytoene	crtI2	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HSJS3_k127_284186_4	218284.CCDN010000001_gene1245	1.618e-21	103.0	COG2324@1|root,COG2324@2|Bacteria,1V4BB@1239|Firmicutes,4HI6A@91061|Bacilli,1ZFZJ@1386|Bacillus	91061|Bacilli	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
HSJS3_k127_284186_0	344747.PM8797T_07207	2.438e-243	775.0	COG0433@1|root,COG0433@2|Bacteria,2IY71@203682|Planctomycetes	203682|Planctomycetes	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87,PDDEXK_1
HSJS3_k127_284186_1	136993.KB900626_gene3694	2.498e-127	424.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,36XH9@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DNA photolyase	phrB	GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
HSJS3_k127_284186_2	1449350.OCH239_08065	1.139e-62	222.0	COG2102@1|root,COG2102@2|Bacteria,1MUU2@1224|Proteobacteria,2U3M8@28211|Alphaproteobacteria,4KNHI@93682|Roseivivax	28211|Alphaproteobacteria	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
HSJS3_k127_284186_5	1131269.AQVV01000022_gene2220	2.219e-13	72.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HSJS3_k127_2907446_0	1267533.KB906737_gene1860	0.0	1125.0	COG0383@1|root,COG0383@2|Bacteria,3Y2RJ@57723|Acidobacteria,2JI5W@204432|Acidobacteriia	204432|Acidobacteriia	G	glycoside hydrolase family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
HSJS3_k127_2907974_1	1200557.JHWV01000002_gene168	1.437e-52	199.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_2907974_2	1121440.AUMA01000020_gene1962	2.403e-15	89.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2M8ZY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HSJS3_k127_2907974_4	643562.Daes_3186	1.79e-11	68.0	COG1937@1|root,COG1937@2|Bacteria,1NIAR@1224|Proteobacteria,42XQ4@68525|delta/epsilon subdivisions,2WRWQ@28221|Deltaproteobacteria,2MCSS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HSJS3_k127_2907974_0	1163407.UU7_05259	1.238e-98	331.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,1RQHJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
HSJS3_k127_2907974_5	888062.HMPREF9083_1195	1.434e-07	63.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,4H9AT@909932|Negativicutes	909932|Negativicutes	U	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,T2SSG
HSJS3_k127_2907974_3	515635.Dtur_0878	4.604e-13	81.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
HSJS3_k127_2914577_1	679201.HMPREF9334_01097	3.01e-43	165.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4H48R@909932|Negativicutes	909932|Negativicutes	S	Bacterial transferase hexapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HSJS3_k127_2914577_0	1120953.AUBH01000004_gene3125	4.152e-48	179.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,46AXN@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
HSJS3_k127_291972_0	1122929.KB908215_gene988	7.294e-61	215.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
HSJS3_k127_291972_1	661478.OP10G_4533	1.996e-30	138.0	2CI0G@1|root,343G2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_2926972_0	1379698.RBG1_1C00001G1502	5.965e-53	192.0	COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HSJS3_k127_2949612_4	1408433.JHXV01000009_gene1189	2.218e-08	63.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia,2PBSD@246874|Cryomorphaceae	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS3_k127_2949612_5	1123060.JONP01000001_gene1441	2.58e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JPRT@204441|Rhodospirillales	204441|Rhodospirillales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
HSJS3_k127_2949612_1	7213.XP_004525523.1	3.625e-20	104.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,41TPQ@6656|Arthropoda,3SGZ4@50557|Insecta,44XMY@7147|Diptera	33208|Metazoa	W	It is involved in the biological process described with signal transduction	SARM1	GO:0002682,GO:0002683,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005856,GO:0005874,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0009611,GO:0009743,GO:0009746,GO:0009749,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010769,GO:0010941,GO:0010975,GO:0015630,GO:0016020,GO:0019867,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030424,GO:0030425,GO:0031090,GO:0031312,GO:0031315,GO:0031344,GO:0031347,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0034121,GO:0034122,GO:0034127,GO:0034128,GO:0034284,GO:0036477,GO:0042221,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043067,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045088,GO:0045202,GO:0045595,GO:0045664,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048678,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051716,GO:0051960,GO:0060284,GO:0065007,GO:0080134,GO:0097447,GO:0097458,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_2949612_3	290317.Cpha266_1840	1.695e-10	74.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria	2|Bacteria	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
HSJS3_k127_2949612_2	7070.TC012668-PA	2.609e-18	99.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,41TPQ@6656|Arthropoda,3SGZ4@50557|Insecta	33208|Metazoa	W	It is involved in the biological process described with signal transduction	SARM1	GO:0002682,GO:0002683,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005856,GO:0005874,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0009611,GO:0009743,GO:0009746,GO:0009749,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010769,GO:0010941,GO:0010975,GO:0015630,GO:0016020,GO:0019867,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030424,GO:0030425,GO:0031090,GO:0031312,GO:0031315,GO:0031344,GO:0031347,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0034121,GO:0034122,GO:0034127,GO:0034128,GO:0034284,GO:0036477,GO:0042221,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043067,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045088,GO:0045202,GO:0045595,GO:0045664,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048678,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051716,GO:0051960,GO:0060284,GO:0065007,GO:0080134,GO:0097447,GO:0097458,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_2949612_0	1123288.SOV_4c07050	3.72e-76	268.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H2ZB@909932|Negativicutes	909932|Negativicutes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HSJS3_k127_2978718_0	1120985.AUMI01000017_gene2643	1.142e-45	176.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes	1239|Firmicutes	G	Belongs to the inositol monophosphatase superfamily	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HSJS3_k127_2980857_1	315749.Bcer98_0224	1.301e-13	81.0	COG0561@1|root,COG0561@2|Bacteria,1VAM3@1239|Firmicutes,4HMW6@91061|Bacilli,1ZQ4D@1386|Bacillus	91061|Bacilli	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HSJS3_k127_2980857_0	1121422.AUMW01000001_gene2493	1.903e-29	128.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,2606Q@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HSJS3_k127_3015348_1	857293.CAAU_2197	1.331e-48	184.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,36EMM@31979|Clostridiaceae	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
HSJS3_k127_3015348_2	760568.Desku_3282	1.288e-23	106.0	COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,24R76@186801|Clostridia,262I1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HSJS3_k127_3015348_0	192952.MM_2234	2.713e-80	277.0	COG5316@1|root,arCOG03524@2157|Archaea,2XZZZ@28890|Euryarchaeota,2NAFM@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
HSJS3_k127_3086379_0	945713.IALB_2925	3.397e-117	388.0	COG3004@1|root,COG3004@2|Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
HSJS3_k127_3086379_4	448385.sce7321	3.735e-40	166.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria,2Z0SK@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HSJS3_k127_3086379_1	557598.LHK_02802	4.282e-76	270.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,2WFJ1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wlbD	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
HSJS3_k127_3086379_2	1173025.GEI7407_2311	2.049e-69	252.0	COG2244@1|root,COG2244@2|Bacteria,1G8R9@1117|Cyanobacteria	1117|Cyanobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
HSJS3_k127_3086379_3	221109.22778574	2.633e-54	200.0	COG0110@1|root,COG0110@2|Bacteria,1V7VQ@1239|Firmicutes,4HKJ5@91061|Bacilli	91061|Bacilli	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HSJS3_k127_3086379_6	357808.RoseRS_4434	5.205e-16	91.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2G9TZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
HSJS3_k127_3086379_5	515635.Dtur_0584	1.95e-35	150.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wblG	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HSJS3_k127_309724_1	479434.Sthe_2389	6.624e-53	194.0	COG4122@1|root,COG4122@2|Bacteria,2G990@200795|Chloroflexi,27ZCN@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HSJS3_k127_309724_0	452637.Oter_2327	7.543e-154	512.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2327|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3119483_2	1378168.N510_02604	7.261e-41	165.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes	1239|Firmicutes	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HSJS3_k127_3119483_0	156889.Mmc1_1764	1.863e-49	187.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria	1224|Proteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767	NAD_kinase
HSJS3_k127_3119483_1	1121405.dsmv_2788	4.996e-48	183.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2MIMF@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HSJS3_k127_3119483_4	350688.Clos_1608	2.969e-32	133.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,36KSA@31979|Clostridiaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
HSJS3_k127_3119483_3	1064537.AGSO01000010_gene2620	2.981e-38	153.0	COG1120@1|root,COG1120@2|Bacteria,2GN5T@201174|Actinobacteria,4FDUI@85020|Dermabacteraceae	201174|Actinobacteria	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HSJS3_k127_3119483_5	555088.DealDRAFT_0689	1.134e-27	122.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,42KYJ@68298|Syntrophomonadaceae	186801|Clostridia	P	PFAM periplasmic binding protein	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HSJS3_k127_3124028_0	635013.TherJR_1108	1.616e-95	326.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,260EJ@186807|Peptococcaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HSJS3_k127_3124028_1	264462.Bd1912	5.21e-84	295.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42S8A@68525|delta/epsilon subdivisions,2MU63@213481|Bdellovibrionales,2WP2E@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HSJS3_k127_3124028_2	211114.JOEF01000002_gene4120	1.309e-23	101.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4E0JN@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HSJS3_k127_3128326_0	204669.Acid345_3484	4.981e-93	319.0	COG0823@1|root,COG0823@2|Bacteria,3Y36H@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HSJS3_k127_3128326_2	309801.trd_0543	2.483e-11	69.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,27XN1@189775|Thermomicrobia	189775|Thermomicrobia	J	DALR anticodon binding domain	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	DALR_1,tRNA-synt_1d
HSJS3_k127_3128326_1	525904.Tter_0438	5.072e-39	156.0	COG0018@1|root,COG0018@2|Bacteria,2NP0H@2323|unclassified Bacteria	2|Bacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HSJS3_k127_3188461_0	1463879.JOHP01000022_gene3292	5.557e-06	59.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
HSJS3_k127_3190628_1	517417.Cpar_0876	1.289e-54	210.0	COG0109@1|root,COG0109@2|Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iJN746.PP_0110,iSB619.SA_RS05465,iSFxv_1172.SFxv_0410,iYO844.BSU12080	UbiA
HSJS3_k127_3190628_0	998674.ATTE01000001_gene3400	1.235e-63	233.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS3_k127_3202457_2	452637.Oter_0597	2.661e-33	136.0	COG4888@1|root,COG4888@2|Bacteria,46UDG@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
HSJS3_k127_3202457_1	1303518.CCALI_02236	2.475e-34	139.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_3202457_0	479434.Sthe_0441	3.49e-65	240.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HSJS3_k127_3245543_0	262724.TT_C1762	7.137e-61	219.0	COG1209@1|root,COG1209@2|Bacteria,1WI71@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HSJS3_k127_3245543_1	1324957.K933_14128	6.697e-57	213.0	COG0153@1|root,arCOG01029@2157|Archaea,2XU7R@28890|Euryarchaeota,23TRG@183963|Halobacteria	183963|Halobacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HSJS3_k127_3276962_2	1064535.MELS_2065	8.72e-05	50.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4H526@909932|Negativicutes	909932|Negativicutes	H	Hydrolase, HD family	-	-	-	-	-	-	-	-	-	-	-	-	HD
HSJS3_k127_3276962_0	211165.AJLN01000045_gene193	4.523e-48	182.0	COG2227@1|root,COG2227@2|Bacteria,1G25I@1117|Cyanobacteria	1117|Cyanobacteria	H	Thiopurine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,TPMT
HSJS3_k127_3276962_1	103733.JNYO01000011_gene4886	6.87e-10	70.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_10,TPR_12,TPR_7,Trans_reg_C
HSJS3_k127_3288818_2	1379698.RBG1_1C00001G1453	4.433e-24	103.0	COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081,iIT341.HP0183	SHMT
HSJS3_k127_3288818_1	439235.Dalk_5032	2.995e-49	180.0	COG0735@1|root,COG0735@2|Bacteria,1Q2NI@1224|Proteobacteria,42SV3@68525|delta/epsilon subdivisions,2WPH8@28221|Deltaproteobacteria,2MKA3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS3_k127_3288818_0	1121899.Q764_12585	2.345e-294	912.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1HWMX@117743|Flavobacteriia,2NSSY@237|Flavobacterium	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
HSJS3_k127_3293497_7	319003.Bra1253DRAFT_02342	7.689e-41	154.0	COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,2U5M6@28211|Alphaproteobacteria,3JY65@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the globin family	MA20_17055	-	1.14.12.17	ko:K05916	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	Globin
HSJS3_k127_3293497_0	997346.HMPREF9374_0342	3.145e-211	670.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,27B33@186824|Thermoactinomycetaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HSJS3_k127_3293497_15	1231190.NA8A_03690	3.606e-06	58.0	COG0810@1|root,COG0810@2|Bacteria,1RESZ@1224|Proteobacteria,2UAM6@28211|Alphaproteobacteria,43RD0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HSJS3_k127_3293497_14	1033802.SSPSH_003676	2.12e-13	78.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
HSJS3_k127_3293497_10	667014.Thein_1996	5.174e-26	115.0	COG0811@1|root,COG0811@2|Bacteria,2GIHG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HSJS3_k127_3293497_8	349521.HCH_05457	5.134e-36	157.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1XJC9@135619|Oceanospirillales	135619|Oceanospirillales	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
HSJS3_k127_3293497_5	1121468.AUBR01000050_gene2015	5.168e-46	177.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HSJS3_k127_3293497_9	1444309.JAQG01000008_gene1713	5.977e-30	126.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,26XIV@186822|Paenibacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HSJS3_k127_3293497_6	1121468.AUBR01000050_gene2015	3.966e-45	173.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HSJS3_k127_3293497_1	1123252.ATZF01000016_gene1646	8.656e-76	263.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,27BNR@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA (Guanine-1)-methyltransferase	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HSJS3_k127_3293497_13	1313265.JNIE01000002_gene754	5.229e-15	83.0	COG0806@1|root,COG0806@2|Bacteria,2G4C8@200783|Aquificae	200783|Aquificae	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HSJS3_k127_3293497_12	573061.Clocel_1904	1.741e-15	78.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,36KGX@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
HSJS3_k127_3293497_11	592015.HMPREF1705_00188	4.146e-24	106.0	COG0228@1|root,COG0228@2|Bacteria,3TBDH@508458|Synergistetes	508458|Synergistetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HSJS3_k127_3293497_3	243231.GSU1968	4.162e-54	205.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,43TN9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HSJS3_k127_3293497_2	1120983.KB894578_gene3677	7.144e-74	269.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2V90G@28211|Alphaproteobacteria,1JQJQ@119043|Rhodobiaceae	28211|Alphaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
HSJS3_k127_3293497_4	1033738.CAEP01000034_gene839	1.364e-48	184.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,26EN1@186818|Planococcaceae	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HSJS3_k127_3308693_1	195103.CPF_2415	4.35e-09	64.0	COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia,36URZ@31979|Clostridiaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
HSJS3_k127_3308693_2	345219.Bcoa_0419	1.107e-07	64.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,1ZC5G@1386|Bacillus	91061|Bacilli	L	DNA repair exonuclease	yhaO	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
HSJS3_k127_3308693_0	13037.EHJ67827	5.11e-87	303.0	COG0372@1|root,KOG2617@2759|Eukaryota,38CK5@33154|Opisthokonta,3BCNS@33208|Metazoa,3CZN5@33213|Bilateria,41WA3@6656|Arthropoda,3SG56@50557|Insecta,445KE@7088|Lepidoptera	33208|Metazoa	C	Citrate synthase, C-terminal domain	CS	GO:0003674,GO:0003824,GO:0004108,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006082,GO:0006084,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0014823,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046483,GO:0046912,GO:0050896,GO:0051186,GO:0055086,GO:0055114,GO:0070013,GO:0071704,GO:0072350,GO:0072521,GO:1901135,GO:1901360,GO:1901564	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HSJS3_k127_3310469_0	1120985.AUMI01000015_gene1548	7.077e-24	117.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4H4F5@909932|Negativicutes	909932|Negativicutes	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,PG_binding_1
HSJS3_k127_331563_9	876269.ARWA01000001_gene2157	6.028e-07	59.0	COG3703@1|root,COG3703@2|Bacteria,1RAZY@1224|Proteobacteria,2U6EG@28211|Alphaproteobacteria,3NAXT@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	AIG2-like family	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2
HSJS3_k127_331563_1	1313172.YM304_38930	1.541e-124	412.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CMR5@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HSJS3_k127_331563_6	344747.PM8797T_07192	8.644e-32	135.0	COG0652@1|root,COG0652@2|Bacteria,2IZWK@203682|Planctomycetes	203682|Planctomycetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HSJS3_k127_331563_5	344747.PM8797T_07192	2.842e-42	168.0	COG0652@1|root,COG0652@2|Bacteria,2IZWK@203682|Planctomycetes	203682|Planctomycetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HSJS3_k127_331563_4	344747.PM8797T_07192	1.348e-45	171.0	COG0652@1|root,COG0652@2|Bacteria,2IZWK@203682|Planctomycetes	203682|Planctomycetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
HSJS3_k127_331563_3	574087.Acear_0602	2.432e-46	181.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3WADT@53433|Halanaerobiales	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
HSJS3_k127_331563_2	1145276.T479_15340	5.185e-98	332.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3IVQQ@400634|Lysinibacillus	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HSJS3_k127_331563_8	5037.XP_001543130.1	2.901e-07	65.0	COG0484@1|root,KOG0550@2759|Eukaryota,38CD1@33154|Opisthokonta,3NV1Y@4751|Fungi,3QQ9D@4890|Ascomycota,20BDM@147545|Eurotiomycetes,3B2PK@33183|Onygenales	4751|Fungi	O	domain-containing protein	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051084,GO:0051085,GO:0061077	-	ko:K09527	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HSJS3_k127_331563_7	1294273.roselon_01049	4.918e-10	69.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HSJS3_k127_331563_0	760568.Desku_2660	1.266e-173	561.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,260NN@186807|Peptococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HSJS3_k127_3341149_0	1479623.JHEL01000015_gene1567	0.0001672	55.0	COG3397@1|root,COG3397@2|Bacteria,2GM54@201174|Actinobacteria	201174|Actinobacteria	L	Chitin-binding domain 3 protein	chb	-	1.14.99.53	ko:K03933,ko:K21713	-	-	-	-	ko00000,ko01000	-	AA10,CBM73	-	LPMO_10
HSJS3_k127_3341514_1	1123489.AUAN01000008_gene110	2.167e-06	58.0	COG3064@1|root,COG3064@2|Bacteria,1U2T9@1239|Firmicutes,4H255@909932|Negativicutes	909932|Negativicutes	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
HSJS3_k127_3341514_0	485913.Krac_3329	1.949e-73	256.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	AAA,TPR_19,TPR_8
HSJS3_k127_3352542_3	765420.OSCT_0415	8.247e-53	201.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi,376Z1@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HSJS3_k127_3352542_2	1479238.JQMZ01000001_gene2248	2.925e-109	372.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,43WB8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HSJS3_k127_3352542_12	1336803.PHEL49_1454	4.521e-07	61.0	COG2010@1|root,COG2010@2|Bacteria,4NWPQ@976|Bacteroidetes,1IN2Q@117743|Flavobacteriia,3VWUB@52959|Polaribacter	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3352542_13	639030.JHVA01000001_gene3757	5.028e-07	61.0	COG1749@1|root,COG2372@1|root,COG4257@1|root,COG4932@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG4257@2|Bacteria,COG4932@2|Bacteria,3Y930@57723|Acidobacteria	57723|Acidobacteria	M	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082
HSJS3_k127_3352542_9	1267533.KB906735_gene4494	4.849e-28	130.0	COG1749@1|root,COG4257@1|root,COG4932@1|root,COG1749@2|Bacteria,COG4257@2|Bacteria,COG4932@2|Bacteria,3Y930@57723|Acidobacteria	57723|Acidobacteria	M	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4082
HSJS3_k127_3352542_6	1304888.ATWF01000002_gene119	9.522e-43	168.0	COG4892@1|root,COG4892@2|Bacteria,2GFKG@200930|Deferribacteres	200930|Deferribacteres	S	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
HSJS3_k127_3352542_10	1035197.HMPREF9999_01092	1.106e-26	109.0	COG1592@1|root,COG1592@2|Bacteria	2|Bacteria	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin,Rubrerythrin
HSJS3_k127_3352542_4	138119.DSY1341	1.562e-49	186.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
HSJS3_k127_3352542_0	592015.HMPREF1705_00314	7.098e-185	595.0	COG4231@1|root,COG4231@2|Bacteria,3T9PR@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
HSJS3_k127_3352542_11	415426.Hbut_1625	7.919e-13	71.0	COG4231@1|root,arCOG01609@2157|Archaea,2XPN3@28889|Crenarchaeota	28889|Crenarchaeota	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
HSJS3_k127_3352542_5	1499967.BAYZ01000179_gene4627	3.59e-44	167.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
HSJS3_k127_3352542_7	1499967.BAYZ01000182_gene4428	8.79e-40	151.0	COG0599@1|root,COG0599@2|Bacteria,2NRHA@2323|unclassified Bacteria	2|Bacteria	O	Carboxymuconolactone decarboxylase family	rnhA	-	3.1.26.4,4.1.1.44	ko:K01607,ko:K03469	ko00362,ko01100,ko01120,ko01220,ko03030,map00362,map01100,map01120,map01220,map03030	-	R03470	RC00938	ko00000,ko00001,ko01000,ko03032	-	-	-	CMD
HSJS3_k127_3352542_8	370438.PTH_1946	9.544e-35	141.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,261K2@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HSJS3_k127_3352542_1	767817.Desgi_0318	5.206e-137	448.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
HSJS3_k127_3357240_28	283942.IL0415	5.592e-14	73.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,2QG4T@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HSJS3_k127_3357240_8	338963.Pcar_1900	8.552e-49	178.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,43URM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L13	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HSJS3_k127_3357240_16	1042156.CXIVA_06410	7.399e-43	168.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,36DP0@31979|Clostridiaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HSJS3_k127_3357240_27	1033737.CAEV01000063_gene2719	9.032e-19	90.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,36IQ8@31979|Clostridiaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HSJS3_k127_3357240_4	1336241.JAEB01000001_gene177	5.36e-66	237.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,25UT6@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HSJS3_k127_3357240_15	1307761.L21SP2_0898	3.752e-43	161.0	COG0100@1|root,COG0100@2|Bacteria,2J7BP@203691|Spirochaetes	203691|Spirochaetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HSJS3_k127_3357240_10	642492.Clole_3520	3.933e-48	175.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HSJS3_k127_3357240_29	553175.POREN0001_0225	1.294e-12	68.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HSJS3_k127_3357240_3	235909.GK0128	1.16e-66	237.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1WEF2@129337|Geobacillus	91061|Bacilli	E	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HSJS3_k127_3357240_12	572546.Arcpr_1334	1.277e-46	175.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
HSJS3_k127_3357240_1	555079.Toce_0138	6.689e-111	372.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,42ESN@68295|Thermoanaerobacterales	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HSJS3_k127_3357240_22	932678.THERU_01490	9.406e-24	106.0	COG0200@1|root,COG0200@2|Bacteria,2G41V@200783|Aquificae	200783|Aquificae	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
HSJS3_k127_3357240_14	1121422.AUMW01000023_gene2770	2.33e-44	171.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,261HV@186807|Peptococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
HSJS3_k127_3357240_18	383372.Rcas_4010	4.445e-35	137.0	COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi,375P7@32061|Chloroflexia	32061|Chloroflexia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
HSJS3_k127_3357240_7	641491.DND132_3415	6.236e-53	191.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,2MB76@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
HSJS3_k127_3357240_19	938289.CAJN020000001_gene1206	3.153e-32	130.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,2696T@186813|unclassified Clostridiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
HSJS3_k127_3357240_26	552811.Dehly_1084	4.628e-20	90.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi,34DIY@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
HSJS3_k127_3357240_5	632335.Calkr_1748	2.744e-62	219.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42F2S@68295|Thermoanaerobacterales	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
HSJS3_k127_3357240_23	1048834.TC41_3030	3.391e-23	103.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,278I9@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
HSJS3_k127_3357240_13	1399115.U719_00535	3.086e-45	168.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3WESB@539002|Bacillales incertae sedis	91061|Bacilli	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
HSJS3_k127_3357240_24	234267.Acid_5109	1.914e-21	96.0	COG0186@1|root,COG0186@2|Bacteria,3Y5I3@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
HSJS3_k127_3357240_9	632518.Calow_1480	1.687e-48	177.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,42G0F@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HSJS3_k127_3357240_6	1121468.AUBR01000044_gene1855	1.087e-61	221.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,42ERW@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HSJS3_k127_3357240_21	1123024.AUII01000003_gene3520	7.187e-26	112.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4E3PV@85010|Pseudonocardiales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
HSJS3_k127_3357240_20	518766.Rmar_0846	5.38e-32	126.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1FJGN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
HSJS3_k127_3357240_2	411471.SUBVAR_05919	1.926e-93	314.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
HSJS3_k127_3357240_30	118163.Ple7327_3480	2.747e-12	70.0	COG0089@1|root,COG0089@2|Bacteria,1G7XC@1117|Cyanobacteria,3VK91@52604|Pleurocapsales	1117|Cyanobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
HSJS3_k127_3357240_25	1235796.C815_02176	6.394e-21	100.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes	1239|Firmicutes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HSJS3_k127_3357240_11	720554.Clocl_3895	5.147e-47	177.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WHH0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HSJS3_k127_3357240_17	913865.DOT_2241	1.284e-40	152.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,2620M@186807|Peptococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HSJS3_k127_3357240_0	994573.T472_0209960	1.931e-119	416.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,36F91@31979|Clostridiaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HSJS3_k127_337230_10	585530.HMPREF0183_1890	6.677e-07	52.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4FAIE@85019|Brevibacteriaceae	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
HSJS3_k127_337230_0	861299.J421_4196	2.843e-294	916.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HSJS3_k127_337230_5	234267.Acid_0589	1.889e-23	112.0	2DBJ5@1|root,2Z9IG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_337230_1	1499967.BAYZ01000177_gene5755	1.188e-174	570.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
HSJS3_k127_337230_3	1408254.T458_21085	3.68e-32	129.0	COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,4HN60@91061|Bacilli,26WT8@186822|Paenibacillaceae	91061|Bacilli	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HSJS3_k127_337230_4	523845.AQXV01000026_gene1469	6.731e-30	139.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
HSJS3_k127_337230_9	717606.PaecuDRAFT_2403	4.341e-07	64.0	COG5498@1|root,COG5498@2|Bacteria,1U7U3@1239|Firmicutes,4IT1H@91061|Bacilli,26SHU@186822|Paenibacillaceae	91061|Bacilli	M	glycoside hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_81,fn3
HSJS3_k127_337230_6	886377.Murru_2512	5.974e-12	78.0	COG5184@1|root,COG5184@2|Bacteria,4NIF9@976|Bacteroidetes,1HZZU@117743|Flavobacteriia	976|Bacteroidetes	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	DUF4988,RCC1,RCC1_2
HSJS3_k127_337230_7	717606.PaecuDRAFT_2403	1.135e-10	74.0	COG5498@1|root,COG5498@2|Bacteria,1U7U3@1239|Firmicutes,4IT1H@91061|Bacilli,26SHU@186822|Paenibacillaceae	91061|Bacilli	M	glycoside hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_81,fn3
HSJS3_k127_337230_2	745310.G432_07405	2.14e-89	315.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2TUA9@28211|Alphaproteobacteria,2K1A5@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase,PBP
HSJS3_k127_337230_8	1455608.JDTH01000006_gene2411	2.037e-09	70.0	COG3979@1|root,arCOG07581@2157|Archaea	1455608.JDTH01000006_gene2411|-	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3373662_0	869210.Marky_1400	8.894e-61	238.0	2FC4C@1|root,34489@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3373662_1	642492.Clole_0684	9.198e-22	104.0	COG0546@1|root,COG0572@1|root,COG0546@2|Bacteria,COG0572@2|Bacteria,1VETJ@1239|Firmicutes	1239|Firmicutes	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48,3.1.3.18	ko:K00876,ko:K01091	ko00240,ko00630,ko00983,ko01100,ko01110,ko01130,map00240,map00630,map00983,map01100,map01110,map01130	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01334,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HSJS3_k127_3376505_0	329726.AM1_1057	8.738e-35	145.0	2DBBI@1|root,2Z888@2|Bacteria,1GR4N@1117|Cyanobacteria	1117|Cyanobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
HSJS3_k127_3380724_1	533247.CRD_02904	5.851e-14	80.0	COG0763@1|root,COG0763@2|Bacteria,1G0V6@1117|Cyanobacteria,1HIBG@1161|Nostocales	1117|Cyanobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HSJS3_k127_3380724_0	986075.CathTA2_0939	5.7e-168	567.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HSJS3_k127_3466386_1	589924.Ferp_0678	0.0003247	54.0	COG3979@1|root,arCOG07581@2157|Archaea,2Y78D@28890|Euryarchaeota,247FP@183980|Archaeoglobi	183980|Archaeoglobi	G	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3466386_0	1296415.JACC01000020_gene3777	0.0001283	56.0	COG3291@1|root,COG4412@1|root,COG5297@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K20276,ko:K21449	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	CARDB,CBM_2,CBM_3,Glyco_hydro_9,PKD,Peptidase_M30
HSJS3_k127_3639818_0	762968.HMPREF9441_01832	5.895e-05	54.0	COG3291@1|root,COG4733@1|root,COG5297@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria,4PNJC@976|Bacteroidetes,2G110@200643|Bacteroidia	976|Bacteroidetes	G	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Laminin_G_3,fn3
HSJS3_k127_3653433_2	865861.AZSU01000002_gene2520	9.862e-37	148.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,36DEP@31979|Clostridiaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HSJS3_k127_3653433_0	880073.Calab_2517	1.153e-126	419.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HSJS3_k127_3653433_1	1304284.L21TH_0036	3.817e-57	216.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HSJS3_k127_3653433_3	641107.CDLVIII_1916	3.375e-28	117.0	COG0730@1|root,COG0730@2|Bacteria,1VAMI@1239|Firmicutes,24MXA@186801|Clostridia,36W1U@31979|Clostridiaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HSJS3_k127_3709035_0	1033739.CAEU01000056_gene469	4.921e-67	240.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,26D4Z@186818|Planococcaceae	91061|Bacilli	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
HSJS3_k127_3709035_1	485913.Krac_7530	1.054e-27	128.0	COG0477@1|root,COG2211@1|root,COG2211@2|Bacteria,COG2814@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_3709035_2	316067.Geob_2842	0.0004091	52.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
HSJS3_k127_3758928_2	469371.Tbis_3287	7.673e-11	72.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
HSJS3_k127_3758928_1	197221.22295107	5.162e-50	193.0	COG0577@1|root,COG0577@2|Bacteria,1G1W4@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type antimicrobial peptide transport system, permease component	salY	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_3758928_0	1499967.BAYZ01000159_gene477	5.075e-60	214.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
HSJS3_k127_3771280_0	324602.Caur_0952	9.957e-73	263.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi,37507@32061|Chloroflexia	32061|Chloroflexia	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
HSJS3_k127_3771280_1	452637.Oter_0742	5.587e-68	242.0	COG1013@1|root,COG1013@2|Bacteria,46SRY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HSJS3_k127_3786298_0	28564.XP_002339929.1	1.667e-38	161.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NW9Q@4751|Fungi,3QJDH@4890|Ascomycota,20AHF@147545|Eurotiomycetes,3S8DS@5042|Eurotiales	4751|Fungi	M	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,NACHT,PNP_UDP_1
HSJS3_k127_3806670_2	344747.PM8797T_17674	5.495e-24	114.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
HSJS3_k127_3806670_3	68570.DC74_8157	7.03e-16	83.0	COG1708@1|root,COG1708@2|Bacteria,2IT8Y@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
HSJS3_k127_3806670_0	483218.BACPEC_03019	2.574e-77	268.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,268CJ@186813|unclassified Clostridiales	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HSJS3_k127_3806670_1	1183438.GKIL_0032	2.179e-69	247.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria	2|Bacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	1.3.1.74	ko:K08070,ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
HSJS3_k127_3862594_3	1123228.AUIH01000038_gene2740	8.686e-10	72.0	COG1361@1|root,COG3291@1|root,COG3656@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG3656@2|Bacteria,1MWIT@1224|Proteobacteria,1S1VQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,PKD
HSJS3_k127_3862594_1	338966.Ppro_2358	8.956e-53	207.0	COG2204@1|root,COG2984@1|root,COG4191@1|root,COG2204@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
HSJS3_k127_3862594_0	1121918.ARWE01000001_gene3224	9.397e-91	309.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,42PJV@68525|delta/epsilon subdivisions,2WKRG@28221|Deltaproteobacteria,43TN5@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HSJS3_k127_3862594_2	1157632.AQWQ01000002_gene4340	8.188e-29	130.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HSJS3_k127_3925765_1	386456.JQKN01000002_gene2422	4.359e-20	101.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,23NUT@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
HSJS3_k127_3925765_0	1218074.BAXZ01000017_gene3473	6.512e-47	178.0	COG2020@1|root,COG2020@2|Bacteria,1RDC4@1224|Proteobacteria,2WFGW@28216|Betaproteobacteria,1K11B@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
HSJS3_k127_3925765_2	1123502.AQXD01000002_gene204	1.341e-14	81.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XCHT@135614|Xanthomonadales	135614|Xanthomonadales	K	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
HSJS3_k127_4021045_1	742766.HMPREF9455_02017	1.512e-40	153.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,2FNBV@200643|Bacteroidia,22W8Q@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C,Radical_SAM
HSJS3_k127_4021045_3	1128421.JAGA01000002_gene428	5.47e-17	85.0	COG2329@1|root,COG2329@2|Bacteria,2NS2V@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	isdG	-	1.14.99.48,1.14.99.57	ko:K07145,ko:K21481	ko00860,ko01110,map00860,map01110	-	R10468,R10510	RC03185	ko00000,ko00001,ko01000	-	-	-	ABM
HSJS3_k127_4021045_4	856793.MICA_2067	3.28e-11	64.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,4BQD8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS3_k127_4021045_2	232348.ADXL01000055_gene1900	3.043e-17	85.0	COG1225@1|root,COG1225@2|Bacteria,1G59X@1117|Cyanobacteria,1H0FU@1129|Synechococcus	1117|Cyanobacteria	O	bacterioferritin comigratory protein	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS3_k127_4021045_0	765910.MARPU_02035	9.869e-113	381.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1WXUR@135613|Chromatiales	135613|Chromatiales	P	PFAM Na Picotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HSJS3_k127_4052814_0	479434.Sthe_1495	1.288e-87	296.0	COG2022@1|root,COG2022@2|Bacteria,2G6DX@200795|Chloroflexi,27XT9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
HSJS3_k127_4052814_1	1094508.Tsac_1981	4.923e-26	121.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,42FE2@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0118	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HSJS3_k127_4052814_2	266264.Rmet_0793	0.000404	47.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2VV9D@28216|Betaproteobacteria,1KGT8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HSJS3_k127_4078201_1	869210.Marky_1209	4.319e-64	228.0	COG0149@1|root,COG0149@2|Bacteria,1WI59@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HSJS3_k127_4078201_2	555793.WSK_0439	4.888e-07	58.0	COG2236@1|root,COG2236@2|Bacteria,1NGI9@1224|Proteobacteria,2UMUF@28211|Alphaproteobacteria,2K4SH@204457|Sphingomonadales	204457|Sphingomonadales	F	phosphoribosyltransferase	-	-	2.4.2.22	ko:K00769,ko:K07101	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HSJS3_k127_4078201_3	1460634.JCM19037_4160	0.000179	52.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HSJS3_k127_4078201_0	706191.PANA_0969	8.909e-73	259.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,3VYFZ@53335|Pantoea	1236|Gammaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.193,3.5.4.26	ko:K01498,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524	RibD_C,dCMP_cyt_deam_1
HSJS3_k127_4091814_3	1449976.KALB_7139	3.55e-05	46.0	COG0491@1|root,COG0491@2|Bacteria,2GN7R@201174|Actinobacteria,4E1FN@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_4091814_0	1128398.Curi_c21840	1.478e-162	531.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,267VP@186813|unclassified Clostridiales	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HSJS3_k127_4091814_1	1198114.AciX9_3595	2.009e-13	77.0	COG0526@1|root,COG0526@2|Bacteria,3Y4MM@57723|Acidobacteria,2JJCE@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS3_k127_4091814_2	945713.IALB_2659	2.293e-13	83.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
HSJS3_k127_4110227_1	642492.Clole_0684	6.573e-22	105.0	COG0546@1|root,COG0572@1|root,COG0546@2|Bacteria,COG0572@2|Bacteria,1VETJ@1239|Firmicutes	1239|Firmicutes	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48,3.1.3.18	ko:K00876,ko:K01091	ko00240,ko00630,ko00983,ko01100,ko01110,ko01130,map00240,map00630,map00983,map01100,map01110,map01130	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01334,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HSJS3_k127_4110227_2	1410620.SHLA_69c000300	0.0003379	51.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,2TRY4@28211|Alphaproteobacteria,4BM2D@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
HSJS3_k127_4110227_0	1238450.VIBNISOn1_800031	5.417e-35	138.0	COG0346@1|root,COG0346@2|Bacteria,1RF7M@1224|Proteobacteria,1S3TZ@1236|Gammaproteobacteria,1XX6E@135623|Vibrionales	135623|Vibrionales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
HSJS3_k127_4111081_5	706587.Desti_0664	2.39e-13	75.0	COG1277@1|root,COG1277@2|Bacteria,1PK2D@1224|Proteobacteria,437V7@68525|delta/epsilon subdivisions,2WWIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
HSJS3_k127_4111081_2	266117.Rxyl_1188	2.232e-48	183.0	COG2846@1|root,COG2846@2|Bacteria,2IKUD@201174|Actinobacteria	201174|Actinobacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
HSJS3_k127_4111081_1	494419.ALPM01000056_gene2961	1.564e-86	297.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,1WBK1@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
HSJS3_k127_4111081_6	1123320.KB889720_gene7504	4.752e-07	64.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
HSJS3_k127_4111081_0	1125863.JAFN01000001_gene2833	1.541e-117	385.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HSJS3_k127_4111081_3	1121405.dsmv_1953	1.921e-42	161.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
HSJS3_k127_4116734_0	1184267.A11Q_801	1.608e-38	156.0	COG0461@1|root,COG0461@2|Bacteria,1Q17P@1224|Proteobacteria,4374Z@68525|delta/epsilon subdivisions,2MTV5@213481|Bdellovibrionales,2WSHR@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HSJS3_k127_4116734_1	477974.Daud_1692	8.543e-22	108.0	COG0438@1|root,COG0438@2|Bacteria,1VN77@1239|Firmicutes	1239|Firmicutes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HSJS3_k127_4117256_1	760568.Desku_0710	2.141e-31	128.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,260C1@186807|Peptococcaceae	186801|Clostridia	C	Acyl-CoA dehydrogenase, N-terminal	-	-	1.3.8.1	ko:K00248,ko:K18244	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HSJS3_k127_4117256_0	1459636.NTE_02403	1.483e-42	162.0	COG0251@1|root,arCOG01630@2157|Archaea,41T4N@651137|Thaumarchaeota	651137|Thaumarchaeota	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HSJS3_k127_4117256_2	237368.SCABRO_01223	8.879e-11	72.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
HSJS3_k127_4137270_0	1047013.AQSP01000139_gene2393	1.345e-48	177.0	COG1704@1|root,COG1704@2|Bacteria,2NPIW@2323|unclassified Bacteria	2|Bacteria	S	LemA family	lemA2	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HSJS3_k127_4137270_1	572477.Alvin_2885	6.771e-48	176.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1WY42@135613|Chromatiales	135613|Chromatiales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HSJS3_k127_4137270_2	1123288.SOV_1c10890	7.83e-09	64.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,4H5W8@909932|Negativicutes	909932|Negativicutes	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4148928_1	1120972.AUMH01000007_gene1700	1.633e-170	547.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,2799H@186823|Alicyclobacillaceae	91061|Bacilli	F	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HSJS3_k127_4148928_15	1303518.CCALI_00107	5.255e-34	136.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HSJS3_k127_4148928_4	515635.Dtur_1604	2.094e-92	318.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HSJS3_k127_4148928_11	1449126.JQKL01000012_gene3510	1.004e-48	188.0	COG0341@1|root,COG0341@2|Bacteria,1TSZE@1239|Firmicutes,249A3@186801|Clostridia,268RB@186813|unclassified Clostridiales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HSJS3_k127_4148928_7	1444309.JAQG01000035_gene2129	1.883e-72	265.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26QNN@186822|Paenibacillaceae	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
HSJS3_k127_4148928_2	292459.STH2437	9.07e-156	518.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
HSJS3_k127_4148928_13	1123237.Salmuc_05404	1.322e-44	166.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2U79I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HSJS3_k127_4148928_3	768704.Desmer_0002	1.833e-114	385.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HSJS3_k127_4148928_14	1121918.ARWE01000001_gene1082	1.197e-35	154.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
HSJS3_k127_4148928_18	1127673.GLIP_2587	7.148e-11	68.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,1SPY1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
HSJS3_k127_4148928_16	1122217.KB899567_gene616	6.855e-29	125.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4H4EK@909932|Negativicutes	909932|Negativicutes	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HSJS3_k127_4148928_12	1206741.BAFX01000096_gene4708	5.219e-47	178.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4FWU0@85025|Nocardiaceae	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2773c	DapB_C,DapB_N
HSJS3_k127_4148928_8	867903.ThesuDRAFT_00219	1.752e-62	232.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WD07@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HSJS3_k127_4148928_6	1123290.AUDQ01000003_gene618	2.746e-75	263.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,26CZF@186818|Planococcaceae	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HSJS3_k127_4148928_9	593117.TGAM_1319	4.328e-60	217.0	COG0846@1|root,arCOG04248@2157|Archaea,2XT4V@28890|Euryarchaeota,2432W@183968|Thermococci	183968|Thermococci	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HSJS3_k127_4148928_0	1123288.SOV_4c06990	2.022e-172	564.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,4H1Y3@909932|Negativicutes	909932|Negativicutes	J	elongation factor G	fusA_1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HSJS3_k127_4148928_17	69781.S8AUN7	1.118e-21	107.0	COG1893@1|root,2QPT5@2759|Eukaryota,39W61@33154|Opisthokonta,3NY0S@4751|Fungi,3QS3S@4890|Ascomycota,20C27@147545|Eurotiomycetes,3SB53@5042|Eurotiales	4751|Fungi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	PAN5	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169,1.14.14.17	ko:K00077,ko:K00511	ko00100,ko00770,ko00909,ko01100,ko01110,ko01130,map00100,map00770,map00909,map01100,map01110,map01130	M00119	R02472,R02874	RC00201,RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HSJS3_k127_4148928_5	696281.Desru_2232	6.217e-83	307.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia,2601V@186807|Peptococcaceae	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	dinG	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T,RadC,ResIII
HSJS3_k127_4148928_10	562970.Btus_0428	1.248e-55	203.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4H9QY@91061|Bacilli,27804@186823|Alicyclobacillaceae	91061|Bacilli	C	Electron transfer flavoprotein domain	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HSJS3_k127_4148928_19	498761.HM1_0891	0.0008789	47.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
HSJS3_k127_4159591_0	522772.Dacet_0369	2.904e-250	788.0	COG0480@1|root,COG0480@2|Bacteria,2GFAG@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HSJS3_k127_4159591_4	1382356.JQMP01000003_gene2257	1.433e-53	192.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HSJS3_k127_4159591_3	880073.Calab_2121	1.279e-62	216.0	COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria	2|Bacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HSJS3_k127_4159591_2	580327.Tthe_1197	2.656e-67	254.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,42EY4@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
HSJS3_k127_4159591_1	1121459.AQXE01000001_gene2820	2.453e-83	287.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2M8FH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM PhoH family protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HSJS3_k127_4159591_5	382464.ABSI01000011_gene2816	4.801e-24	110.0	COG4888@1|root,COG4888@2|Bacteria,46UDG@74201|Verrucomicrobia	2|Bacteria	O	PFAM ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HSJS3_k127_4164092_3	886293.Sinac_3001	0.000718	48.0	2DW63@1|root,33YPW@2|Bacteria,2J3GX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4164092_1	1219084.AP014508_gene211	7.871e-35	143.0	COG1670@1|root,COG1670@2|Bacteria,2GCZ2@200918|Thermotogae	200918|Thermotogae	J	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
HSJS3_k127_4164092_2	1282362.AEAC466_04025	8.023e-15	87.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2KFMT@204458|Caulobacterales	204458|Caulobacterales	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HSJS3_k127_4164092_0	755178.Cyan10605_3134	2.945e-109	378.0	COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HSJS3_k127_4183686_2	1324957.K933_16552	2.426e-08	66.0	COG3291@1|root,COG3979@1|root,arCOG02499@1|root,arCOG07560@1|root,arCOG02499@2157|Archaea,arCOG02508@2157|Archaea,arCOG07560@2157|Archaea,arCOG07581@2157|Archaea,2Y80Y@28890|Euryarchaeota,24124@183963|Halobacteria	183963|Halobacteria	G	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HSJS3_k127_4183686_1	366602.Caul_2222	4.8e-36	145.0	COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria,2U808@28211|Alphaproteobacteria,2KHJ2@204458|Caulobacterales	204458|Caulobacterales	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
HSJS3_k127_4183686_0	645991.Sgly_2669	2.145e-58	205.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,26041@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
HSJS3_k127_4192498_0	1382306.JNIM01000001_gene527	6.017e-43	167.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HSJS3_k127_4192498_1	40571.JOEA01000014_gene2102	6.9e-14	79.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4E31I@85010|Pseudonocardiales	201174|Actinobacteria	O	Redoxin	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS3_k127_4195762_0	1000569.HMPREF1040_0905	8.902e-121	415.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
HSJS3_k127_4195762_1	1476583.DEIPH_ctg066orf0021	0.0005938	46.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	ko:K11938	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_3
HSJS3_k127_4214049_1	316279.Syncc9902_0472	2.194e-16	93.0	COG1333@1|root,COG1333@2|Bacteria,1G0R9@1117|Cyanobacteria,1GYPZ@1129|Synechococcus	1117|Cyanobacteria	O	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment	ccs1	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
HSJS3_k127_4214049_0	1122164.JHWF01000001_gene1958	4.492e-46	177.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1JCST@118969|Legionellales	118969|Legionellales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HSJS3_k127_4222432_2	1048834.TC41_2034	1.1e-35	144.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,278BH@186823|Alicyclobacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
HSJS3_k127_4222432_1	1226325.HMPREF1548_05676	6.795e-37	147.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,36I7Z@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HSJS3_k127_4222432_3	1123500.ATUU01000003_gene1305	2.321e-35	148.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,4AXAS@81850|Leuconostocaceae	91061|Bacilli	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HSJS3_k127_4222432_4	56780.SYN_01352	2.303e-26	109.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HSJS3_k127_4222432_5	754027.HMPREF9554_00785	2.185e-13	76.0	COG0261@1|root,COG0261@2|Bacteria,2J7PP@203691|Spirochaetes	203691|Spirochaetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HSJS3_k127_4222432_0	28444.JODQ01000001_gene2323	1.292e-47	177.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4EFV0@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
HSJS3_k127_424142_4	509191.AEDB02000022_gene2925	1.686e-16	94.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,3WIT1@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,Peptidase_S8,SLH
HSJS3_k127_424142_0	886293.Sinac_1297	1.181e-81	278.0	COG4221@1|root,COG4221@2|Bacteria,2J3BF@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HSJS3_k127_424142_1	525904.Tter_0015	4.136e-60	224.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
HSJS3_k127_424142_3	1280950.HJO_14231	3.097e-18	90.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,43YAG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
HSJS3_k127_424142_7	1408813.AYMG01000001_gene3658	0.0001418	55.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IQVH@117747|Sphingobacteriia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
HSJS3_k127_424142_6	1123239.KB898623_gene1594	1.096e-08	61.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli	91061|Bacilli	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
HSJS3_k127_424142_2	7460.GB51500-PA	1.269e-23	117.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,41TPQ@6656|Arthropoda,3SGZ4@50557|Insecta,46I0C@7399|Hymenoptera	33208|Metazoa	W	SAM domain (Sterile alpha motif)	SARM1	GO:0002682,GO:0002683,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005856,GO:0005874,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0009611,GO:0009743,GO:0009746,GO:0009749,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010769,GO:0010941,GO:0010975,GO:0015630,GO:0016020,GO:0019867,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030424,GO:0030425,GO:0031090,GO:0031312,GO:0031315,GO:0031344,GO:0031347,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0034121,GO:0034122,GO:0034127,GO:0034128,GO:0034284,GO:0036477,GO:0042221,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043067,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045088,GO:0045202,GO:0045595,GO:0045664,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048678,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051716,GO:0051960,GO:0060284,GO:0065007,GO:0080134,GO:0097447,GO:0097458,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_424142_5	485913.Krac_1108	3.463e-16	93.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	485913.Krac_1108|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_424142_8	309798.COPRO5265_0399	0.0002306	49.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,24ACH@186801|Clostridia,42GEA@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
HSJS3_k127_4255187_1	203122.Sde_2587	2.071e-25	113.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,4642M@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
HSJS3_k127_4255187_2	1009370.ALO_15742	3.335e-12	79.0	28HBQ@1|root,2Z7NP@2|Bacteria,1UZ1V@1239|Firmicutes,4H3EF@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4255187_0	1408423.JHYA01000012_gene1563	3.446e-48	190.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HSJS3_k127_4260480_3	743525.TSC_c16680	2.459e-08	60.0	COG1974@1|root,COG1974@2|Bacteria,1WKJJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	Peptidase S24-like	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_31,Peptidase_S24
HSJS3_k127_4260480_4	46429.BV95_02889	0.0001358	49.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,2K5QM@204457|Sphingomonadales	204457|Sphingomonadales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_4260480_2	696369.KI912183_gene2596	1.178e-12	71.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia	186801|Clostridia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_4260480_0	796942.HMPREF9623_01021	1.453e-22	105.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia	186801|Clostridia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
HSJS3_k127_4275617_2	1384057.CD33_01420	6.345e-08	65.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HBCY@91061|Bacilli,3IWWX@400634|Lysinibacillus	91061|Bacilli	S	ABC transporter substrate-binding protein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HSJS3_k127_4275617_3	1128421.JAGA01000002_gene1062	1.441e-06	60.0	COG5180@1|root,COG5180@2|Bacteria,2NRZJ@2323|unclassified Bacteria	2|Bacteria	A	pathogenesis	CP_0034	-	-	ko:K02417,ko:K02519	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044,ko03012,ko03029	3.A.6.2,3.A.6.3	-	-	GPDPase_memb
HSJS3_k127_4275617_0	1089553.Tph_c11140	3.415e-86	297.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,42ENB@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HSJS3_k127_4275617_1	525146.Ddes_0347	4.458e-67	239.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2M9B7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HSJS3_k127_4329695_1	637390.AFOH01000132_gene1879	3.503e-09	60.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,2NCE1@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
HSJS3_k127_4329695_2	1284352.AOIG01000019_gene3674	0.0005953	53.0	COG4676@1|root,COG5492@1|root,COG4676@2|Bacteria,COG5492@2|Bacteria,1VAUC@1239|Firmicutes,4HN5U@91061|Bacilli,26SQP@186822|Paenibacillaceae	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
HSJS3_k127_4329695_0	1341155.FSS13T_19040	3.979e-25	123.0	COG4676@1|root,COG4676@2|Bacteria,4NISW@976|Bacteroidetes,1I0BF@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4329793_0	471852.Tcur_3618	1.131e-80	271.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4EFM1@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
HSJS3_k127_4333728_0	357808.RoseRS_2451	0.00027	53.0	COG4870@1|root,COG4932@1|root,COG5513@1|root,COG4870@2|Bacteria,COG4932@2|Bacteria,COG5513@2|Bacteria,2GA24@200795|Chloroflexi,377PH@32061|Chloroflexia	2|Bacteria	MO	Carboxypeptidase regulatory-like domain	-	-	3.4.22.15	ko:K01365,ko:K02030,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	M00236	-	-	ko00000,ko00001,ko00002,ko00537,ko01000,ko01002,ko02000,ko03110	3.A.1.3	-	-	CarboxypepD_reg,Inhibitor_I42,Peptidase_C1
HSJS3_k127_4333728_1	83219.PM02_00550	0.0006819	53.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,3ZV8F@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
HSJS3_k127_4384642_1	706587.Desti_5082	2.416e-11	75.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MRYH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
HSJS3_k127_4384642_0	592028.GCWU000321_00849	5.268e-21	106.0	COG3203@1|root,COG3203@2|Bacteria,1V1RK@1239|Firmicutes,4H431@909932|Negativicutes	909932|Negativicutes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5,SLH
HSJS3_k127_447198_0	264462.Bd0765	1.734e-31	128.0	COG2259@1|root,COG2259@2|Bacteria,1NCQT@1224|Proteobacteria,42WUM@68525|delta/epsilon subdivisions,2WT9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HSJS3_k127_447198_1	574087.Acear_2174	8.838e-20	104.0	COG3203@1|root,COG3203@2|Bacteria,1VEU4@1239|Firmicutes,24SCU@186801|Clostridia,3WCBJ@53433|Halanaerobiales	186801|Clostridia	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373,SLH
HSJS3_k127_447198_2	1123511.KB905839_gene427	3.301e-06	55.0	COG0816@1|root,COG0816@2|Bacteria,1V9WY@1239|Firmicutes,4H57J@909932|Negativicutes	909932|Negativicutes	L	Likely ribonuclease with RNase H fold.	-	-	-	-	-	-	-	-	-	-	-	-	RuvX,Tex_YqgF
HSJS3_k127_4502199_1	1500893.JQNB01000001_gene1934	2.069e-55	204.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1X3J5@135614|Xanthomonadales	135614|Xanthomonadales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HSJS3_k127_4502199_0	1117314.PCIT_11009	1.842e-115	389.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,2Q08R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
HSJS3_k127_4502199_5	518766.Rmar_2411	6.923e-09	60.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1FJ1C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HSJS3_k127_4502199_2	760568.Desku_1363	6.816e-49	179.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
HSJS3_k127_4502199_3	608538.HTH_0759	1.679e-36	144.0	COG0290@1|root,COG0290@2|Bacteria,2G432@200783|Aquificae	200783|Aquificae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HSJS3_k127_4502199_4	2074.JNYD01000032_gene6518	3.612e-10	66.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4E6HS@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HSJS3_k127_4502199_6	1121472.AQWN01000001_gene179	3.017e-05	46.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,2627I@186807|Peptococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HSJS3_k127_453778_2	203119.Cthe_2146	0.0002743	47.0	COG4124@1|root,COG4124@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM27,CBM_11,Glyco_hydro_26
HSJS3_k127_453778_0	1121405.dsmv_1117	8.153e-22	108.0	COG1503@1|root,COG1503@2|Bacteria,1MXX2@1224|Proteobacteria,42U2M@68525|delta/epsilon subdivisions,2WQS1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_453778_1	1125718.HMPREF1318_0376	7.509e-09	60.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,4D44A@85005|Actinomycetales	201174|Actinobacteria	L	GIY-YIG catalytic domain protein	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
HSJS3_k127_4602521_2	1121434.AULY01000007_gene1420	3.673e-13	80.0	COG1271@1|root,COG1271@2|Bacteria,1QXQF@1224|Proteobacteria,42NKJ@68525|delta/epsilon subdivisions,2WKHM@28221|Deltaproteobacteria,2M95S@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	oxidase subunit	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	-
HSJS3_k127_4602521_3	756067.MicvaDRAFT_4941	6.693e-07	60.0	2BZE4@1|root,33IEP@2|Bacteria,1GCXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4602521_0	479434.Sthe_2325	2.107e-96	329.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HSJS3_k127_4602521_1	309807.SRU_2126	2.819e-18	88.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1FIVY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HSJS3_k127_4608001_2	91464.S7335_2237	2.075e-15	84.0	COG1511@1|root,COG1511@2|Bacteria,1G2V0@1117|Cyanobacteria,1H06M@1129|Synechococcus	1117|Cyanobacteria	S	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HSJS3_k127_4608001_4	1453501.JELR01000001_gene3191	5.153e-06	56.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,4675S@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
HSJS3_k127_4608001_1	1303518.CCALI_00830	3.977e-19	101.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4608001_0	357808.RoseRS_0991	2.067e-32	147.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
HSJS3_k127_4608001_3	1227484.C471_09180	1.145e-14	89.0	COG2133@1|root,COG3794@1|root,arCOG02796@2157|Archaea,arCOG02921@2157|Archaea,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	Copper-bind,DUF4399,GSDH,Laminin_G_3,Malectin,ThuA
HSJS3_k127_4624552_0	349741.Amuc_0540	6.611e-114	377.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HSJS3_k127_4624552_1	1278073.MYSTI_06291	6.952e-10	70.0	2EDTI@1|root,337NU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_4640340_2	1029823.AFIE01000002_gene2328	4.387e-33	133.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,1RPYB@1236|Gammaproteobacteria,3NIGJ@468|Moraxellaceae	1236|Gammaproteobacteria	S	Winged helix DNA-binding domain	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
HSJS3_k127_4640340_0	118163.Ple7327_0425	6.061e-122	404.0	COG0436@1|root,COG0436@2|Bacteria,1GHX7@1117|Cyanobacteria,3VM7E@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HSJS3_k127_4640340_1	1121423.JONT01000010_gene1749	7.279e-83	287.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25ZYS@186807|Peptococcaceae	186801|Clostridia	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HSJS3_k127_4640340_5	755732.Fluta_0704	0.0008371	48.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
HSJS3_k127_4640340_4	5888.CAK66383	0.0002464	51.0	KOG0599@1|root,KOG0599@2759|Eukaryota	5888.CAK66383|-	G	phosphorylase kinase activity	-	-	2.7.11.19	ko:K00871	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	-
HSJS3_k127_4640340_3	1504822.CCNO01000015_gene842	6.97e-06	56.0	COG1381@1|root,COG1381@2|Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HSJS3_k127_4644253_3	1163407.UU7_02712	1.629e-42	163.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
HSJS3_k127_4644253_0	1333523.L593_06205	3.837e-106	373.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
HSJS3_k127_4644253_2	1120973.AQXL01000126_gene2926	3.103e-87	310.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27891@186823|Alicyclobacillaceae	91061|Bacilli	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HSJS3_k127_4644253_1	1266925.JHVX01000004_gene1173	1.264e-89	299.0	COG0020@1|root,COG0020@2|Bacteria,1PWDF@1224|Proteobacteria,2WBY6@28216|Betaproteobacteria,3740E@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Putative undecaprenyl diphosphate synthase	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HSJS3_k127_4683457_0	485913.Krac_0431	4.98e-80	282.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HSJS3_k127_4688120_0	880073.Calab_3076	1.608e-132	458.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NNKC@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HSJS3_k127_4700405_0	1449050.JNLE01000003_gene940	5.069e-119	406.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HSJS3_k127_4700405_1	459349.CLOAM1019	3.35e-118	402.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	3.6.3.44	ko:K06147,ko:K06148,ko:K11085,ko:K16787,ko:K18104,ko:K18889	ko01501,ko02010,map01501,map02010	M00582,M00700,M00707	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
HSJS3_k127_4700405_2	1173028.ANKO01000160_gene5070	2.03e-56	204.0	COG0637@1|root,COG0637@2|Bacteria,1G6EG@1117|Cyanobacteria,1HD99@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
HSJS3_k127_4729094_1	394221.Mmar10_1223	0.0002439	54.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2TSJ3@28211|Alphaproteobacteria,43WEQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Chaperone SurA	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N,SurA_N_3
HSJS3_k127_4729094_0	171693.BN988_00721	1.107e-47	182.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,23IJ9@182709|Oceanobacillus	91061|Bacilli	D	SMC proteins Flexible Hinge Domain	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HSJS3_k127_4756992_2	518766.Rmar_2792	7.526e-39	153.0	COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,1FJW7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HSJS3_k127_4756992_0	1385935.N836_34170	5.562e-116	394.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
HSJS3_k127_4756992_1	713586.KB900536_gene2396	2.17e-42	170.0	COG2227@1|root,COG2227@2|Bacteria,1R0J0@1224|Proteobacteria	1224|Proteobacteria	H	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
HSJS3_k127_4764254_0	383372.Rcas_2353	2.454e-79	276.0	COG1131@1|root,COG1131@2|Bacteria,2G5YX@200795|Chloroflexi,3762X@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_4764254_1	861299.J421_0325	2.051e-38	156.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HSJS3_k127_4764254_2	1205910.B005_0867	0.0002586	47.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria	201174|Actinobacteria	K	AntiSigma factor	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
HSJS3_k127_4802794_4	1089439.KB902242_gene1134	1.552e-06	61.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales	72273|Thiotrichales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HSJS3_k127_4802794_3	686340.Metal_0728	2.534e-16	87.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,1RNQH@1236|Gammaproteobacteria,1XE72@135618|Methylococcales	135618|Methylococcales	K	PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
HSJS3_k127_4802794_1	1408473.JHXO01000004_gene19	4.439e-75	268.0	COG0701@1|root,COG0701@2|Bacteria,4NDUJ@976|Bacteroidetes,2FNF8@200643|Bacteroidia	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,HMA
HSJS3_k127_4802794_2	1713.JOFV01000013_gene1013	2.318e-41	158.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4F2NG@85016|Cellulomonadaceae	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HSJS3_k127_4802794_0	706587.Desti_3017	1.565e-98	363.0	COG0784@1|root,COG2202@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
HSJS3_k127_4821886_1	945713.IALB_3128	2.436e-08	66.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
HSJS3_k127_4821886_0	1303518.CCALI_02735	4.009e-153	497.0	COG1220@1|root,COG1220@2|Bacteria	2|Bacteria	O	peptidase activity, acting on L-amino acid peptides	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
HSJS3_k127_4830064_0	1125863.JAFN01000001_gene2835	6.33e-122	412.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
HSJS3_k127_4830064_1	1125863.JAFN01000001_gene2836	6.712e-67	232.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WNNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
HSJS3_k127_4851493_1	1033743.CAES01000091_gene2877	1.163e-64	244.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos,SLH
HSJS3_k127_4851493_0	1033743.CAES01000033_gene1139	6.169e-96	342.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HSJS3_k127_4852470_0	1120965.AUBV01000004_gene851	9.411e-69	240.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
HSJS3_k127_4867886_1	717605.Theco_2562	1.241e-21	109.0	COG2340@1|root,COG2340@2|Bacteria,1TSUX@1239|Firmicutes,4HDMJ@91061|Bacilli,26TNZ@186822|Paenibacillaceae	91061|Bacilli	G	CAP-associated N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CAP_assoc_N,SLH
HSJS3_k127_4867886_0	1192034.CAP_8821	3.979e-50	184.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS3_k127_496687_6	1379698.RBG1_1C00001G0066	6.084e-73	257.0	COG1305@1|root,COG1305@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
HSJS3_k127_496687_10	1267535.KB906767_gene4079	2.016e-26	113.0	COG0720@1|root,COG0720@2|Bacteria,3Y4HE@57723|Acidobacteria,2JJ9Q@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HSJS3_k127_496687_13	926564.KI911710_gene2850	8.422e-06	59.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4F3H9@85017|Promicromonosporaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,CBM_6,GSDH,PKD
HSJS3_k127_496687_11	1127673.GLIP_1220	3.105e-13	84.0	COG3210@1|root,COG4676@1|root,COG5184@1|root,COG3210@2|Bacteria,COG4676@2|Bacteria,COG5184@2|Bacteria,1QUH2@1224|Proteobacteria,1S0HN@1236|Gammaproteobacteria,467W1@72275|Alteromonadaceae	1236|Gammaproteobacteria	DZ	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_496687_8	880073.Calab_2875	2.684e-53	196.0	COG0704@1|root,COG0704@2|Bacteria,2NPWX@2323|unclassified Bacteria	2|Bacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HSJS3_k127_496687_1	765914.ThisiDRAFT_2348	8.446e-104	346.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales	135613|Chromatiales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HSJS3_k127_496687_4	1395587.P364_0132860	3.447e-83	291.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,26U7E@186822|Paenibacillaceae	91061|Bacilli	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HSJS3_k127_496687_3	926550.CLDAP_00830	7.817e-98	329.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HSJS3_k127_496687_0	402777.KB235904_gene4257	5.168e-114	379.0	COG0226@1|root,COG0226@2|Bacteria,1FZZ0@1117|Cyanobacteria,1H7JB@1150|Oscillatoriales	1117|Cyanobacteria	P	Phosphate ABC transporter substrate-binding protein, PhoT family	sphX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
HSJS3_k127_496687_2	1121422.AUMW01000033_gene3367	1.996e-103	359.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
HSJS3_k127_496687_7	370438.PTH_1831	2.034e-65	238.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HSJS3_k127_496687_9	1032480.MLP_45460	8.628e-35	149.0	COG4990@1|root,COG4990@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
HSJS3_k127_496687_12	935840.JAEQ01000002_gene3277	2.53e-06	56.0	2E5IZ@1|root,330AA@2|Bacteria,1N9JX@1224|Proteobacteria,2UVN3@28211|Alphaproteobacteria,43QQP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_496687_5	926569.ANT_25430	1.642e-80	278.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HSJS3_k127_5003467_4	1385511.N783_21000	1.998e-21	104.0	COG0477@1|root,COG2814@2|Bacteria,1V6VB@1239|Firmicutes,4IT0A@91061|Bacilli,2YATF@289201|Pontibacillus	91061|Bacilli	EGP	Major Facilitator Superfamily	pmrB	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS3_k127_5003467_0	1121920.AUAU01000010_gene46	1.888e-124	413.0	COG0165@1|root,COG0165@2|Bacteria,3Y36Y@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HSJS3_k127_5003467_1	1278073.MYSTI_05595	9.869e-99	336.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,43BFP@68525|delta/epsilon subdivisions,2WMVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HSJS3_k127_5003467_2	1278073.MYSTI_05594	1.736e-76	268.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HSJS3_k127_5003467_3	378806.STAUR_5869	9.106e-47	173.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2YYG6@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HSJS3_k127_5104777_0	1123319.AUBE01000007_gene3735	8.043e-90	310.0	COG0399@1|root,COG0451@1|root,COG0399@2|Bacteria,COG0451@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1,Epimerase
HSJS3_k127_5104777_1	1121448.DGI_2278	1.278e-13	72.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WKPT@28221|Deltaproteobacteria,2M8SR@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HSJS3_k127_531762_0	313606.M23134_07544	2.758e-65	235.0	COG5553@1|root,COG5553@2|Bacteria,4NT62@976|Bacteroidetes	976|Bacteroidetes	C	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
HSJS3_k127_531762_1	391587.KAOT1_02597	1.968e-45	170.0	COG1247@1|root,COG1247@2|Bacteria,4NPIE@976|Bacteroidetes,1I2DZ@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphinothricin acetyltransferase	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
HSJS3_k127_5361501_1	398767.Glov_3125	6.559e-81	287.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HSJS3_k127_5361501_0	316067.Geob_0474	2.788e-83	284.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HSJS3_k127_5378620_9	338966.Ppro_1677	5.645e-42	174.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2WNND@28221|Deltaproteobacteria,43T13@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HSJS3_k127_5378620_0	1123376.AUIU01000002_gene1663	4.872e-276	872.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HSJS3_k127_5378620_14	373903.Hore_01660	1.733e-14	78.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,3WAX2@53433|Halanaerobiales	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
HSJS3_k127_5378620_8	795797.C497_06017	3.973e-62	231.0	COG0604@1|root,arCOG01458@2157|Archaea,2XU74@28890|Euryarchaeota,23T36@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor2	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_5378620_4	1041930.Mtc_1965	1.177e-89	313.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
HSJS3_k127_5378620_15	240016.ABIZ01000001_gene1019	1.889e-13	77.0	COG3011@1|root,COG3011@2|Bacteria,46WSM@74201|Verrucomicrobia,2IUZ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
HSJS3_k127_5378620_13	1121918.ARWE01000001_gene2160	1.261e-18	92.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2X67B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
HSJS3_k127_5378620_6	1379698.RBG1_1C00001G0780	5.906e-64	226.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
HSJS3_k127_5378620_12	1232410.KI421425_gene1569	2.993e-24	107.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,43TZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome b(C-terminal)/b6/petD	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
HSJS3_k127_5378620_5	1379698.RBG1_1C00001G0779	1.795e-67	248.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
HSJS3_k127_5378620_3	671143.DAMO_0826	1.358e-96	333.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569,ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrome_C7
HSJS3_k127_5378620_10	765914.ThisiDRAFT_2684	4.749e-36	142.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HSJS3_k127_5378620_11	555779.Dthio_PD1962	8.408e-27	112.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HSJS3_k127_5378620_1	498848.TaqDRAFT_4327	1.897e-170	548.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
HSJS3_k127_5378620_7	1219084.AP014508_gene878	9.171e-63	237.0	COG0367@1|root,COG0367@2|Bacteria,2GE6X@200918|Thermotogae	200918|Thermotogae	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	-
HSJS3_k127_5378620_2	266117.Rxyl_1110	1.201e-167	541.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
HSJS3_k127_54129_1	326424.FRAAL6340	1.271e-25	118.0	COG2319@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3629@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,Pentapeptide,Pkinase,TIR_2,WD40
HSJS3_k127_54129_2	306281.AJLK01000162_gene45	2.532e-19	91.0	COG1225@1|root,COG1225@2|Bacteria,1G59X@1117|Cyanobacteria,1JIFT@1189|Stigonemataceae	1117|Cyanobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS3_k127_54129_3	269084.syc2152_c	5.963e-09	58.0	COG1225@1|root,COG1225@2|Bacteria,1G59X@1117|Cyanobacteria,1H0FU@1129|Synechococcus	1117|Cyanobacteria	O	bacterioferritin comigratory protein	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HSJS3_k127_54129_0	1449063.JMLS01000057_gene6166	1.995e-30	128.0	COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HFYI@91061|Bacilli,275KD@186822|Paenibacillaceae	91061|Bacilli	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
HSJS3_k127_5470327_2	504728.K649_03445	8.285e-72	246.0	COG1902@1|root,COG1902@2|Bacteria,1WIIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HSJS3_k127_5470327_4	1384049.CD29_18425	8.724e-23	104.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,3IZGY@400634|Lysinibacillus	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
HSJS3_k127_5470327_1	102129.Lepto7375DRAFT_1120	1.691e-89	304.0	COG5424@1|root,COG5424@2|Bacteria,1G36V@1117|Cyanobacteria	1117|Cyanobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5470327_0	204669.Acid345_2004	1.073e-158	507.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
HSJS3_k127_5470327_3	1294265.JCM21738_1209	1.422e-67	238.0	COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,1ZCD1@1386|Bacillus	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
HSJS3_k127_548035_4	314230.DSM3645_01981	2.771e-68	243.0	COG4531@1|root,COG4531@2|Bacteria,2IY65@203682|Planctomycetes	203682|Planctomycetes	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_548035_3	314230.DSM3645_01971	3.261e-69	244.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HSJS3_k127_548035_1	344747.PM8797T_11881	7.719e-87	301.0	COG1622@1|root,COG3474@1|root,COG1622@2|Bacteria,COG3474@2|Bacteria,2IXB7@203682|Planctomycetes	203682|Planctomycetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
HSJS3_k127_548035_0	521674.Plim_3990	1.434e-240	754.0	COG0843@1|root,COG0843@2|Bacteria,2IXCQ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HSJS3_k127_548035_2	1123242.JH636436_gene298	1.55e-69	246.0	COG1845@1|root,COG1845@2|Bacteria,2IYXN@203682|Planctomycetes	203682|Planctomycetes	C	Heme copper-type cytochrome quinol oxidase, subunit	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HSJS3_k127_548035_6	521674.Plim_3992	5.458e-19	93.0	2EAMQ@1|root,338KI@2|Bacteria,2J0SC@203682|Planctomycetes	203682|Planctomycetes	S	Prokaryotic Cytochrome C oxidase subunit IV	ctaF	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
HSJS3_k127_548035_7	1356852.N008_13435	1.32e-12	76.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,47NS2@768503|Cytophagia	976|Bacteroidetes	C	PFAM cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
HSJS3_k127_548035_5	1122176.KB903532_gene2585	1.323e-55	207.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HSJS3_k127_5489739_0	479434.Sthe_0669	5.374e-73	254.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HSJS3_k127_5489739_2	266117.Rxyl_2460	9.634e-29	122.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
HSJS3_k127_5489739_3	1120936.KB907219_gene3091	1.543e-05	53.0	COG2146@1|root,COG2146@2|Bacteria,2IKSY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	Rieske
HSJS3_k127_5489739_1	1123386.AUIW01000002_gene1322	1.066e-42	161.0	COG5322@1|root,COG5322@2|Bacteria,1WI86@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5498613_0	1192034.CAP_5480	1.763e-88	299.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2YZE8@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
HSJS3_k127_5498613_1	1304875.JAFZ01000001_gene1226	5.049e-83	285.0	COG0190@1|root,COG0190@2|Bacteria,3TAFK@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HSJS3_k127_5498613_2	1267533.KB906734_gene3891	6.646e-29	125.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HSJS3_k127_5498613_3	439235.Dalk_2648	8.626e-20	93.0	COG0694@1|root,COG0822@1|root,COG1251@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,COG1251@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MIAE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
HSJS3_k127_5504468_6	1444310.JANV01000136_gene2617	0.0002311	48.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ywkD	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
HSJS3_k127_5504468_1	1220534.B655_2316	1.49e-21	100.0	COG5483@1|root,arCOG00723@2157|Archaea,2XYZG@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
HSJS3_k127_5504468_0	43179.ENSSTOP00000023437	1.279e-22	113.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,480B1@7711|Chordata,48X7E@7742|Vertebrata,3J8UG@40674|Mammalia,35H7N@314146|Euarchontoglires,4PY18@9989|Rodentia	33208|Metazoa	W	Sterile alpha and TIR motif-containing protein 1	SARM1	GO:0002682,GO:0002683,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005856,GO:0005874,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0009611,GO:0009743,GO:0009746,GO:0009749,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010769,GO:0010941,GO:0010975,GO:0015630,GO:0016020,GO:0019867,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030424,GO:0030425,GO:0031090,GO:0031312,GO:0031315,GO:0031344,GO:0031347,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0034121,GO:0034122,GO:0034127,GO:0034128,GO:0034284,GO:0036477,GO:0042221,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043067,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045088,GO:0045202,GO:0045595,GO:0045664,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048678,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051716,GO:0051960,GO:0060284,GO:0065007,GO:0080134,GO:0097447,GO:0097458,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_5504468_5	56110.Oscil6304_0015	1.301e-10	74.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G20P@1117|Cyanobacteria,1HEJ9@1150|Oscillatoriales	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_8
HSJS3_k127_5504468_2	135651.CBN21367	2.669e-16	93.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,40CB6@6231|Nematoda,1KUS9@119089|Chromadorea,40U4I@6236|Rhabditida	33208|Metazoa	W	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_5504468_3	290317.Cpha266_1840	2.669e-16	93.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria	2|Bacteria	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
HSJS3_k127_5504468_4	7260.FBpp0249078	1.522e-15	79.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,41TPQ@6656|Arthropoda,3SGZ4@50557|Insecta,44XMY@7147|Diptera,45VQD@7214|Drosophilidae	33208|Metazoa	W	It is involved in the biological process described with signal transduction	SARM1	GO:0002682,GO:0002683,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005856,GO:0005874,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0009611,GO:0009743,GO:0009746,GO:0009749,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010769,GO:0010941,GO:0010975,GO:0015630,GO:0016020,GO:0019867,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030424,GO:0030425,GO:0031090,GO:0031312,GO:0031315,GO:0031344,GO:0031347,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0034121,GO:0034122,GO:0034127,GO:0034128,GO:0034284,GO:0036477,GO:0042221,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043067,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045088,GO:0045202,GO:0045595,GO:0045664,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048678,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051716,GO:0051960,GO:0060284,GO:0065007,GO:0080134,GO:0097447,GO:0097458,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_5510160_1	1232410.KI421426_gene1359	1.813e-134	457.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,43SE5@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HSJS3_k127_5510160_2	1313421.JHBV01000014_gene3897	2.024e-66	238.0	28JUF@1|root,2Z9JH@2|Bacteria,4NHS3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RskA
HSJS3_k127_5510160_3	243090.RB7297	3.158e-40	154.0	COG4067@1|root,COG4067@2|Bacteria,2J12V@203682|Planctomycetes	203682|Planctomycetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
HSJS3_k127_5510160_0	696747.NIES39_J00050	1.499e-142	457.0	COG0189@1|root,COG0189@2|Bacteria,1G0DT@1117|Cyanobacteria,1H6ZT@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,Zn_protease
HSJS3_k127_5510160_6	1197906.CAJQ02000027_gene1525	3.744e-05	48.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HSJS3_k127_5510160_4	582515.KR51_00007690	2.156e-14	83.0	COG0500@1|root,COG2226@2|Bacteria,1G3V3@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HSJS3_k127_5510160_5	450851.PHZ_c3166	1.39e-05	52.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,2KGBU@204458|Caulobacterales	204458|Caulobacterales	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HSJS3_k127_5512076_7	562970.Btus_0750	3.008e-34	153.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,277ZN@186823|Alicyclobacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	apr	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HSJS3_k127_5512076_6	1282876.BAOK01000002_gene616	5.895e-39	151.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,4BQ6F@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HSJS3_k127_5512076_2	667014.Thein_1217	5.161e-98	329.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HSJS3_k127_5512076_0	273068.TTE1784	1.077e-125	416.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,42FF6@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HSJS3_k127_5512076_8	765914.ThisiDRAFT_2862	2.648e-28	122.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria,1S6QY@1236|Gammaproteobacteria,1X11Y@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HSJS3_k127_5512076_4	459349.CLOAM0275	2.676e-59	236.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
HSJS3_k127_5512076_5	1256908.HMPREF0373_00026	1.39e-41	171.0	COG0076@1|root,COG0076@2|Bacteria,1TSK0@1239|Firmicutes,24A90@186801|Clostridia,25XSN@186806|Eubacteriaceae	186801|Clostridia	E	Pyridoxal-dependent decarboxylase conserved domain	ddc	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
HSJS3_k127_5512076_1	211165.AJLN01000116_gene3143	2.638e-102	339.0	COG3483@1|root,COG3483@2|Bacteria,1GKQY@1117|Cyanobacteria,1JMKF@1189|Stigonemataceae	1117|Cyanobacteria	E	Tryptophan 2,3-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_dioxygenase
HSJS3_k127_5512076_3	457570.Nther_2022	3.23e-79	275.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia	2|Bacteria	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HSJS3_k127_5515005_3	479434.Sthe_2445	1.553e-41	164.0	COG0697@1|root,COG0697@2|Bacteria,2G8R9@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS3_k127_5515005_2	300852.55771436	3.69e-43	162.0	COG0219@1|root,COG0219@2|Bacteria,1WKB4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HSJS3_k127_5515005_4	1121877.JQKF01000027_gene2479	3.692e-39	153.0	COG0780@1|root,COG0780@2|Bacteria,2GS82@201174|Actinobacteria,4CNEJ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
HSJS3_k127_5515005_9	1122614.JHZF01000011_gene1512	3.942e-06	55.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,2U8HG@28211|Alphaproteobacteria,2PE2J@252301|Oceanicola	28211|Alphaproteobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB
HSJS3_k127_5515005_1	1267535.KB906767_gene210	5.411e-130	429.0	COG3004@1|root,COG3004@2|Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
HSJS3_k127_5515005_0	997346.HMPREF9374_2435	1.188e-134	439.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27BAA@186824|Thermoactinomycetaceae	91061|Bacilli	I	Thiolase, C-terminal domain	mmgA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
HSJS3_k127_5515005_6	2325.TKV_c18590	2.061e-33	142.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HSJS3_k127_5515005_8	1007096.BAGW01000006_gene1789	1.127e-16	93.0	COG0169@1|root,COG0703@1|root,COG0169@2|Bacteria,COG0703@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2N701@216572|Oscillospiraceae	186801|Clostridia	E	Shikimate kinase	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
HSJS3_k127_5515005_7	459349.CLOAM1805	6.682e-28	120.0	COG1478@1|root,COG1478@2|Bacteria	2|Bacteria	S	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	F420_ligase
HSJS3_k127_5538903_2	1169144.KB910924_gene461	4.313e-12	78.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,1ZFNB@1386|Bacillus	91061|Bacilli	D	Cell division initiation protein	divIVA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
HSJS3_k127_5538903_3	1461580.CCAS010000047_gene3496	1.781e-05	51.0	COG0762@1|root,COG0762@2|Bacteria,1UAJ7@1239|Firmicutes,4IKXR@91061|Bacilli,1ZI8W@1386|Bacillus	91061|Bacilli	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
HSJS3_k127_5538903_1	717606.PaecuDRAFT_2403	5.656e-17	96.0	COG5498@1|root,COG5498@2|Bacteria,1U7U3@1239|Firmicutes,4IT1H@91061|Bacilli,26SHU@186822|Paenibacillaceae	91061|Bacilli	M	glycoside hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_81,fn3
HSJS3_k127_5538903_0	1173027.Mic7113_3755	3.969e-66	244.0	COG0612@1|root,COG0612@2|Bacteria,1G3GH@1117|Cyanobacteria,1H8R7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HSJS3_k127_5573066_0	1191523.MROS_0480	3.225e-109	367.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HSJS3_k127_5573066_1	926556.Echvi_1560	9.993e-97	323.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47KCJ@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HSJS3_k127_5573746_1	243231.GSU3016	4.265e-86	321.0	COG0823@1|root,COG2885@1|root,COG3291@1|root,COG4412@1|root,COG5492@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5492@2|Bacteria,1PMFY@1224|Proteobacteria,42Y8D@68525|delta/epsilon subdivisions,2WUNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
HSJS3_k127_5573746_5	1121459.AQXE01000020_gene760	3.619e-41	168.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
HSJS3_k127_5573746_2	383372.Rcas_2765	2.022e-65	230.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi,375YQ@32061|Chloroflexia	32061|Chloroflexia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HSJS3_k127_5573746_4	1094508.Tsac_1684	1.561e-47	190.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,42FS4@68295|Thermoanaerobacterales	186801|Clostridia	D	Stage II sporulation D domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
HSJS3_k127_5573746_3	1122994.AUFR01000004_gene707	3.603e-55	209.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DN32@85009|Propionibacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
HSJS3_k127_5573746_0	649638.Trad_0897	1.13e-191	616.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HSJS3_k127_5581626_4	1122939.ATUD01000006_gene1683	5.079e-17	92.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4CS70@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
HSJS3_k127_5581626_5	95619.PM1_0202805	2.971e-07	63.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC-Type Dipeptide Transport System Periplasmic Component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HSJS3_k127_5581626_3	272123.Anacy_4112	3.319e-39	161.0	COG1409@1|root,COG1409@2|Bacteria,1G1J1@1117|Cyanobacteria,1HKKV@1161|Nostocales	1117|Cyanobacteria	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HSJS3_k127_5581626_0	518766.Rmar_0472	1.305e-244	773.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1FIXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
HSJS3_k127_5581626_1	266117.Rxyl_0056	4.723e-151	484.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
HSJS3_k127_5581626_2	443254.Marpi_0243	7.694e-69	239.0	COG0740@1|root,COG0740@2|Bacteria,2GC7E@200918|Thermotogae	200918|Thermotogae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HSJS3_k127_5581626_6	243231.GSU3177	4.135e-07	56.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,43UM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	tssI	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
HSJS3_k127_5582753_1	1121413.JMKT01000011_gene2245	1.694e-79	292.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1
HSJS3_k127_5582753_2	56780.SYN_00173	1.13e-27	116.0	COG0784@1|root,COG0784@2|Bacteria,1QUK7@1224|Proteobacteria,431U0@68525|delta/epsilon subdivisions,2WW6W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HSJS3_k127_5582753_0	537013.CLOSTMETH_03273	1.971e-148	475.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3WHW6@541000|Ruminococcaceae	186801|Clostridia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HSJS3_k127_5585555_1	1449126.JQKL01000038_gene971	1.036e-53	200.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,2688N@186813|unclassified Clostridiales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HSJS3_k127_5585555_0	292459.STH3333	4.996e-90	302.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HSJS3_k127_5592280_5	570268.ANBB01000003_gene430	0.0005396	50.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M15_4
HSJS3_k127_5592280_4	661478.OP10G_1058	3.896e-05	54.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
HSJS3_k127_5592280_0	673860.AciM339_1462	1.155e-174	564.0	COG3404@1|root,arCOG05394@2157|Archaea,arCOG05395@2157|Archaea,2XX41@28890|Euryarchaeota,3F3A8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
HSJS3_k127_5592280_2	398767.Glov_1672	4.168e-49	188.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
HSJS3_k127_5592280_1	498761.HM1_2316	5.753e-54	203.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HSJS3_k127_5592280_3	1217656.F964_01252	1.47e-11	70.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,3NN3B@468|Moraxellaceae	1236|Gammaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HSJS3_k127_5613181_2	1123386.AUIW01000004_gene686	6.607e-13	71.0	COG0205@1|root,COG0205@2|Bacteria,1WINW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HSJS3_k127_5613181_0	290397.Adeh_1764	1.779e-206	655.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
HSJS3_k127_5613181_1	880073.Calab_3613	2.922e-85	295.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944	-	ko:K00412,ko:K02635,ko:K02637,ko:K03887,ko:K03891,ko:K15879	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
HSJS3_k127_5613181_3	1382306.JNIM01000001_gene3494	1.239e-12	75.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K03886	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00151,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
HSJS3_k127_5613598_2	742767.HMPREF9456_00361	0.0003357	51.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,2FQPG@200643|Bacteroidia,22YCD@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
HSJS3_k127_5613598_0	1121374.KB891575_gene1200	2.678e-119	398.0	COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,1RP1J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
HSJS3_k127_5613598_1	1089545.KB913037_gene1860	3.181e-12	67.0	COG0604@1|root,COG0604@2|Bacteria,2IJFY@201174|Actinobacteria	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HSJS3_k127_5627729_1	335541.Swol_2383	3.848e-44	170.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,42K9T@68298|Syntrophomonadaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HSJS3_k127_5627729_6	1347086.CCBA010000030_gene305	1.685e-10	66.0	29RJN@1|root,30CNU@2|Bacteria,1UA58@1239|Firmicutes,4IKFQ@91061|Bacilli,1ZGVS@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5627729_0	246194.CHY_2547	4.453e-211	668.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,42F4E@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HSJS3_k127_5627729_3	1286171.EAL2_c03890	2.603e-24	109.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,25WJZ@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HSJS3_k127_5627729_5	1379698.RBG1_1C00001G0148	2.11e-14	79.0	COG0711@1|root,COG0711@2|Bacteria,2NQ34@2323|unclassified Bacteria	2|Bacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HSJS3_k127_5627729_4	1437425.CSEC_0649	1.403e-21	96.0	COG0636@1|root,COG0636@2|Bacteria,2JGFR@204428|Chlamydiae	204428|Chlamydiae	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HSJS3_k127_5627729_2	1379698.RBG1_1C00001G0146	5.309e-27	123.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HSJS3_k127_5629148_0	1217718.ALOU01000007_gene1258	2.45e-42	168.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2W0N2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
HSJS3_k127_56406_0	518766.Rmar_0304	3.538e-58	214.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1FJQT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	4Fe-4S double cluster binding domain	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
HSJS3_k127_56406_1	195250.CM001776_gene1606	1.192e-11	70.0	COG0330@1|root,COG0330@2|Bacteria,1G8KV@1117|Cyanobacteria,1GZHD@1129|Synechococcus	1117|Cyanobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
HSJS3_k127_564762_0	880073.Calab_3076	2.798e-124	434.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NNKC@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HSJS3_k127_5695889_0	1121468.AUBR01000008_gene2046	1.974e-199	640.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,42EN9@68295|Thermoanaerobacterales	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HSJS3_k127_5695889_6	504472.Slin_4777	5.154e-28	125.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47N2D@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HSJS3_k127_5695889_9	1185653.A1A1_09211	5.192e-05	53.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,26ERH@186818|Planococcaceae	91061|Bacilli	CO	Catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HSJS3_k127_5695889_5	1131814.JAFO01000001_gene3163	4.531e-38	149.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria,3F1DB@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HSJS3_k127_5695889_7	1463901.JOIY01000008_gene2854	8.08e-13	74.0	COG3832@1|root,COG3832@2|Bacteria,2IKRA@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HSJS3_k127_5695889_2	1223410.KN050846_gene2047	1.838e-82	280.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1HYH3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HSJS3_k127_5695889_10	530564.Psta_1036	0.000124	52.0	COG0526@1|root,COG0526@2|Bacteria,2J3XG@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5695889_11	537013.CLOSTMETH_01475	0.0008668	42.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3WGK1@541000|Ruminococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
HSJS3_k127_5695889_1	502025.Hoch_1352	1.648e-119	393.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YU5C@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS3_k127_5695889_4	1121104.AQXH01000001_gene1835	2.487e-42	163.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
HSJS3_k127_5695889_3	404589.Anae109_0218	1.082e-70	254.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2YU9T@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HSJS3_k127_5695889_8	1280944.HY17_07285	2.334e-07	64.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,1QVGM@1224|Proteobacteria,2TWFQ@28211|Alphaproteobacteria,440P6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
HSJS3_k127_5707860_1	278963.ATWD01000001_gene1367	4.534e-06	58.0	COG1538@1|root,COG1538@2|Bacteria,3Y3JU@57723|Acidobacteria,2JI92@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HSJS3_k127_5707860_0	626939.HMPREF9443_01044	1.333e-36	145.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4H3YU@909932|Negativicutes	909932|Negativicutes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HSJS3_k127_5713819_5	886293.Sinac_7377	8.458e-09	67.0	COG2165@1|root,COG2165@2|Bacteria,2J2WG@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
HSJS3_k127_5713819_1	880073.Calab_2862	8.964e-87	301.0	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,PAS_3,Response_reg,dCache_2
HSJS3_k127_5713819_2	1379698.RBG1_1C00001G0167	1.498e-64	224.0	COG1898@1|root,COG1898@2|Bacteria,2NP7U@2323|unclassified Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
HSJS3_k127_5713819_4	562970.Btus_3259	1.48e-19	91.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli,27A86@186823|Alicyclobacillaceae	91061|Bacilli	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HSJS3_k127_5713819_3	292459.STH72	7.29e-46	181.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia	186801|Clostridia	J	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
HSJS3_k127_5713819_0	1286171.EAL2_c03760	1.787e-106	354.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25V56@186806|Eubacteriaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HSJS3_k127_5780470_4	272558.10174146	2.33e-52	190.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus	91061|Bacilli	L	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HSJS3_k127_5780470_1	373903.Hore_17900	2.768e-97	331.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,3WAGT@53433|Halanaerobiales	186801|Clostridia	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
HSJS3_k127_5780470_3	406124.ACPC01000020_gene3904	6.217e-55	205.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,1ZBZB@1386|Bacillus	91061|Bacilli	M	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
HSJS3_k127_5780470_0	644966.Tmar_0462	1.291e-97	341.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3WDH0@538999|Clostridiales incertae sedis	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
HSJS3_k127_5780470_2	1227276.HMPREF9148_00207	1.092e-79	282.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,2FNP7@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HSJS3_k127_5784849_3	387631.Asulf_02259	1.883e-54	195.0	COG0105@1|root,arCOG04313@2157|Archaea,2XWSK@28890|Euryarchaeota,2465T@183980|Archaeoglobi	183980|Archaeoglobi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HSJS3_k127_5784849_0	1284352.AOIG01000041_gene2990	5.786e-212	670.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
HSJS3_k127_5784849_2	1185653.A1A1_09911	3.695e-158	509.0	COG0026@1|root,COG0026@2|Bacteria,1TTDR@1239|Firmicutes,4HDHY@91061|Bacilli	91061|Bacilli	F	Carboxylate--amine ligase	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
HSJS3_k127_5784849_1	218284.CCDN010000002_gene2147	4.019e-193	622.0	2C593@1|root,2Z84R@2|Bacteria,1U546@1239|Firmicutes,4HEHB@91061|Bacilli,1ZMHC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5794008_0	309807.SRU_2235	3.093e-73	271.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1FIP7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HSJS3_k127_5848131_0	1111069.TCCBUS3UF1_40	5.127e-123	413.0	COG0469@1|root,COG0469@2|Bacteria,1WJAC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the pyruvate kinase family	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HSJS3_k127_5848131_1	1122185.N792_05765	1.686e-69	257.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,1RQUG@1236|Gammaproteobacteria,1X59Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
HSJS3_k127_5848131_2	1246459.KB898356_gene2280	2.636e-67	248.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,2TUBP@28211|Alphaproteobacteria,4B77J@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
HSJS3_k127_5861492_0	1379698.RBG1_1C00001G0798	1.347e-89	313.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
HSJS3_k127_5861492_2	349521.HCH_00733	3.289e-33	139.0	29681@1|root,2ZTI1@2|Bacteria,1RA8W@1224|Proteobacteria,1SAMV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
HSJS3_k127_5861492_1	765869.BDW_12915	3.453e-68	239.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2MT3P@213481|Bdellovibrionales,2WNJ6@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HSJS3_k127_5861492_3	742743.HMPREF9453_01303	2.477e-16	81.0	COG3203@1|root,COG3203@2|Bacteria,1V1RK@1239|Firmicutes,4H33J@909932|Negativicutes	909932|Negativicutes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4,Porin_5,SLH
HSJS3_k127_5863910_1	868131.MSWAN_0727	2.103e-60	224.0	COG0527@1|root,arCOG00861@2157|Archaea,2XTJ0@28890|Euryarchaeota,23NKX@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the aspartokinase family	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
HSJS3_k127_5863910_2	572547.Amico_1489	9.167e-18	95.0	COG3660@1|root,COG3660@2|Bacteria,3T9WA@508458|Synergistetes	508458|Synergistetes	M	Nucleoside-diphosphate-sugar epimerase	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
HSJS3_k127_5863910_0	292459.STH463	2.513e-105	354.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS3_k127_5881919_1	768670.Calni_1007	2.026e-40	161.0	COG0543@1|root,COG0543@2|Bacteria,2GF6C@200930|Deferribacteres	200930|Deferribacteres	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
HSJS3_k127_5881919_0	641143.HMPREF9331_02315	1.852e-88	297.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia,1EQZ1@1016|Capnocytophaga	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HSJS3_k127_5881919_2	272562.CA_C3071	6.703e-27	112.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia,36EHG@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_5907343_5	387631.Asulf_00090	3.588e-05	48.0	arCOG09475@1|root,arCOG09475@2157|Archaea,2Y37E@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,PKD
HSJS3_k127_5907343_3	1380356.JNIK01000021_gene4449	8.276e-32	137.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4ESHS@85013|Frankiales	201174|Actinobacteria	I	Phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
HSJS3_k127_5907343_0	1278073.MYSTI_00905	6.733e-109	372.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,43BX1@68525|delta/epsilon subdivisions,2X77U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HSJS3_k127_5907343_4	1236902.ANAS01000044_gene2150	4.35e-08	63.0	COG0596@1|root,COG0596@2|Bacteria,2I2VI@201174|Actinobacteria,4EIRZ@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HSJS3_k127_5907343_1	194439.CT1987	2.79e-65	239.0	COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HSJS3_k127_5907343_2	1128421.JAGA01000003_gene3359	1.363e-63	235.0	COG1233@1|root,COG1233@2|Bacteria,2NQ26@2323|unclassified Bacteria	2|Bacteria	Q	Flavin containing amine oxidoreductase	crtD	-	1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9	ko:K01854,ko:K09845,ko:K10027	ko00052,ko00520,ko00906,ko01100,ko01110,map00052,map00520,map00906,map01100,map01110	-	R00505,R04787,R04798,R04800,R07517,R07520,R07523,R07534,R09009,R09691,R09692	RC00317,RC01214,RC02080,RC02088,RC02396,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HSJS3_k127_5913535_0	1121272.KB903249_gene2209	3.266e-243	786.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,2HVJC@201174|Actinobacteria,4DHAD@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase 101 beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101
HSJS3_k127_5913535_1	1267534.KB906755_gene4821	3.064e-156	521.0	COG3345@1|root,COG3345@2|Bacteria,3Y44J@57723|Acidobacteria,2JIVW@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5913535_3	243365.CV_2309	4.862e-123	405.0	COG1299@1|root,COG1299@2|Bacteria,1MXFN@1224|Proteobacteria,2VK5D@28216|Betaproteobacteria,2KSKJ@206351|Neisseriales	2|Bacteria	G	PTS system, fructose subfamily, IIC subunit	fruA-1	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K11203	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273,M00306	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HSJS3_k127_5913535_4	243365.CV_2310	8.283e-35	135.0	COG1445@1|root,COG1445@2|Bacteria,1N1D8@1224|Proteobacteria	1224|Proteobacteria	G	PFAM phosphotransferase system PTS fructose-specific IIB subunit	-	-	2.7.1.202	ko:K02769,ko:K11202	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273,M00306	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_IIB
HSJS3_k127_5913535_2	155864.EDL933_5283	4.522e-152	512.0	COG1080@1|root,COG1762@1|root,COG1925@1|root,COG1080@2|Bacteria,COG1762@2|Bacteria,COG1925@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,3XP7E@561|Escherichia	1236|Gammaproteobacteria	G	Multifunctional protein that includes general (non sugar-specific) and sugar-specific components of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FrwABC PTS system is involved in fructose transport	ptsA	-	2.7.3.9	ko:K08483,ko:K11189,ko:K11201	ko02060,map02060	M00306	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
HSJS3_k127_59281_0	575540.Isop_3374	3.88e-28	121.0	COG1743@1|root,COG1943@1|root,COG1743@2|Bacteria,COG1943@2|Bacteria,2J099@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07445	-	-	-	-	ko00000	-	-	-	Y1_Tnp
HSJS3_k127_5930399_2	195103.CPF_2581	1.619e-68	240.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,36DG5@31979|Clostridiaceae	186801|Clostridia	I	Dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HSJS3_k127_5930399_3	1120958.AULD01000009_gene792	6.504e-06	51.0	COG0695@1|root,COG0695@2|Bacteria,2GQ85@201174|Actinobacteria,4FQ09@85023|Microbacteriaceae	201174|Actinobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
HSJS3_k127_5930399_1	292459.STH3174	1.599e-104	344.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia	186801|Clostridia	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
HSJS3_k127_5930399_0	1348908.KI518589_gene2582	2.933e-127	418.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05640	FAD_binding_2,Succ_DH_flav_C
HSJS3_k127_5931230_0	1410618.JNKI01000002_gene1009	4.819e-91	327.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HSJS3_k127_5931230_5	883126.HMPREF9710_01633	4.148e-10	69.0	COG0515@1|root,COG0515@2|Bacteria,1NEBV@1224|Proteobacteria,2VXYK@28216|Betaproteobacteria,474X1@75682|Oxalobacteraceae	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5931230_3	604331.AUHY01000046_gene1820	1.38e-20	100.0	COG0632@1|root,COG0632@2|Bacteria,1WKAU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HSJS3_k127_5931230_1	1121344.JHZO01000004_gene1736	4.129e-31	128.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,3WIS5@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HSJS3_k127_5931230_6	1298863.AUEP01000003_gene2728	0.0007465	53.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HSJS3_k127_5931230_4	697281.Mahau_1114	3.814e-11	78.0	COG2730@1|root,COG4733@1|root,COG2730@2|Bacteria,COG4733@2|Bacteria,1TT6J@1239|Firmicutes,24CXA@186801|Clostridia	186801|Clostridia	G	hydrolase family 5	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_X2,Cellulase
HSJS3_k127_5931230_2	314230.DSM3645_26649	1.111e-20	107.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
HSJS3_k127_5951592_1	1122223.KB890699_gene519	2.296e-26	113.0	COG5637@1|root,COG5637@2|Bacteria,1WNGI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
HSJS3_k127_5951592_0	523845.AQXV01000026_gene1469	1.21e-42	181.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
HSJS3_k127_5951592_2	292459.STH718	3.196e-19	104.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,PPC,Peptidase_S8
HSJS3_k127_5964666_1	720554.Clocl_1094	4.407e-05	55.0	2E0UQ@1|root,32WC3@2|Bacteria,1UK0E@1239|Firmicutes,25FGA@186801|Clostridia,3WK6S@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_5964666_0	1123389.ATXJ01000011_gene1035	1.421e-28	121.0	COG3877@1|root,COG3877@2|Bacteria,1WKFA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
HSJS3_k127_5969667_2	631362.Thi970DRAFT_03256	3.725e-54	211.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1S0W3@1236|Gammaproteobacteria,1WX5N@135613|Chromatiales	135613|Chromatiales	KL	DNA RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
HSJS3_k127_5969667_0	317619.ANKN01000158_gene1787	3.903e-99	336.0	COG1473@1|root,COG1473@2|Bacteria,1G01G@1117|Cyanobacteria,1MKFU@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	ama	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HSJS3_k127_5969667_1	292459.STH462	2.337e-65	240.0	COG1721@1|root,COG1721@2|Bacteria,1UYJ3@1239|Firmicutes,24FK2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS3_k127_5969667_4	235909.GK2665	2.843e-35	141.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1WF41@129337|Geobacillus	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HSJS3_k127_5969667_7	1144275.COCOR_07145	1.536e-05	58.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	nreA	-	4.6.1.1	ko:K01768,ko:K02283,ko:K10851,ko:K21685	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044,ko03000	-	-	-	BTAD,FHA,GAF_2,GerE,Guanylate_cyc
HSJS3_k127_5969667_5	1191299.AJYX01000115_gene17	4.129e-14	86.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RNRU@1236|Gammaproteobacteria,1XU1F@135623|Vibrionales	135623|Vibrionales	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
HSJS3_k127_5969667_6	1122182.KB903815_gene1485	1.954e-10	71.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4DB9K@85008|Micromonosporales	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
HSJS3_k127_5969667_3	41431.PCC8801_0049	1.62e-35	143.0	COG1878@1|root,COG1878@2|Bacteria,1GD8S@1117|Cyanobacteria,3KK69@43988|Cyanothece	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
HSJS3_k127_6021932_0	626939.HMPREF9443_01786	3.074e-70	246.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H38B@909932|Negativicutes	909932|Negativicutes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HSJS3_k127_6021932_1	935948.KE386494_gene241	1.147e-27	114.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HSJS3_k127_6021932_2	1163617.SCD_n00850	7.898e-07	56.0	2EBKH@1|root,335KX@2|Bacteria,1NAWH@1224|Proteobacteria,2W4UC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6055763_0	1121920.AUAU01000006_gene293	1.188e-202	661.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HSJS3_k127_6055763_1	999547.KI421502_gene3770	8.068e-83	279.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TTJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
HSJS3_k127_6084879_0	1408439.JHXW01000003_gene1446	5.151e-43	158.0	COG1137@1|root,COG1137@2|Bacteria,379CC@32066|Fusobacteria	32066|Fusobacteria	S	K06861 lipopolysaccharide export system ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
HSJS3_k127_6084879_1	439235.Dalk_2289	4.894e-21	109.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
HSJS3_k127_6084879_3	199306.XP_003071866.1	5.493e-06	53.0	28NNH@1|root,2R38G@2759|Eukaryota,39NSW@33154|Opisthokonta,3P007@4751|Fungi,3QKD3@4890|Ascomycota,20CHS@147545|Eurotiomycetes,3B0Q0@33183|Onygenales,3FM9D@34383|Onygenales incertae sedis	4751|Fungi	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
HSJS3_k127_6084879_2	1502852.FG94_02021	5.273e-21	93.0	COG0735@1|root,COG0735@2|Bacteria,1N18Z@1224|Proteobacteria,2VSUH@28216|Betaproteobacteria,477A9@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HSJS3_k127_6101055_2	1116232.AHBF01000013_gene3068	2.519e-59	214.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HSJS3_k127_6101055_0	383372.Rcas_1200	3.504e-250	798.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi,3753A@32061|Chloroflexia	32061|Chloroflexia	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HSJS3_k127_6101055_4	247490.KSU1_B0647	1.039e-54	198.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6101055_5	671143.DAMO_0350	1.917e-53	201.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6101055_6	330214.NIDE2490	1.128e-50	188.0	29ZH8@1|root,30MGZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6101055_1	247490.KSU1_B0650	2.473e-101	344.0	28MEN@1|root,2ZASA@2|Bacteria,2IZ1H@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6101973_0	998674.ATTE01000001_gene127	5.712e-68	255.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HSJS3_k127_6101973_1	500635.MITSMUL_04802	1.513e-08	61.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4H2TV@909932|Negativicutes	909932|Negativicutes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HSJS3_k127_6123976_1	1279009.ADICEAN_00292	5.711e-36	143.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HSJS3_k127_6123976_0	1121423.JONT01000003_gene1127	2.448e-83	284.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,2603P@186807|Peptococcaceae	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HSJS3_k127_6123976_2	383372.Rcas_0356	1.187e-21	99.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,375IS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM ParB domain protein nuclease	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HSJS3_k127_616916_1	568703.LGG_00821	3.351e-09	58.0	292C0@1|root,2ZPWE@2|Bacteria,1W1IU@1239|Firmicutes,4I189@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_616916_0	866895.HBHAL_4803	7.067e-23	111.0	COG0726@1|root,COG0726@2|Bacteria,1VW0P@1239|Firmicutes,4HWHY@91061|Bacilli,3NEID@45667|Halobacillus	91061|Bacilli	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HSJS3_k127_6222759_2	760192.Halhy_1524	8.104e-14	78.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HSJS3_k127_6222759_0	382464.ABSI01000010_gene3794	5.548e-173	587.0	COG4888@1|root,COG4888@2|Bacteria,46UDG@74201|Verrucomicrobia	2|Bacteria	O	PFAM ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HSJS3_k127_6222759_1	935848.JAEN01000007_gene2875	2.588e-171	553.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,2PW0I@265|Paracoccus	28211|Alphaproteobacteria	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HSJS3_k127_6238605_0	215803.DB30_0065	4.654e-45	169.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2YUHV@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HSJS3_k127_6238605_1	264732.Moth_0916	1.936e-44	169.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,42GDH@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HSJS3_k127_6238605_2	348780.NP_3878A	2.635e-08	61.0	COG1397@1|root,arCOG04448@2157|Archaea,2XV15@28890|Euryarchaeota,23TFB@183963|Halobacteria	183963|Halobacteria	O	ADP-ribosyl-(Dinitrogen reductase) hydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
HSJS3_k127_6282131_2	1121374.KB891590_gene1661	9.668e-26	123.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HSJS3_k127_6282131_1	751945.Theos_0766	6.589e-110	367.0	COG0045@1|root,COG0045@2|Bacteria,1WIT1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HSJS3_k127_6282131_0	572547.Amico_1375	1.328e-161	533.0	COG0272@1|root,COG0272@2|Bacteria,3T9WY@508458|Synergistetes	508458|Synergistetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HSJS3_k127_6312198_1	641143.HMPREF9331_01413	5.735e-08	55.0	COG4260@1|root,COG4260@2|Bacteria,4NHXG@976|Bacteroidetes,1I0MU@117743|Flavobacteriia,1ERQM@1016|Capnocytophaga	976|Bacteroidetes	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT
HSJS3_k127_6312198_0	494419.ALPM01000075_gene1569	4.1e-10	71.0	COG0810@1|root,COG3401@1|root,COG4733@1|root,COG0810@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PA14
HSJS3_k127_6385591_1	536227.CcarbDRAFT_3629	2.158e-08	65.0	COG1585@1|root,COG1585@2|Bacteria,1VD3E@1239|Firmicutes,24H38@186801|Clostridia,36IDP@31979|Clostridiaceae	186801|Clostridia	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449,NfeD
HSJS3_k127_6385591_0	452637.Oter_2033	1.487e-79	272.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
HSJS3_k127_6522783_2	1123371.ATXH01000033_gene420	5.048e-12	76.0	COG0133@1|root,COG0133@2|Bacteria,2GGRX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS3_k127_6522783_1	1449126.JQKL01000014_gene2974	1.291e-21	106.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HSJS3_k127_6522783_0	110319.CF8_2498	1.054e-52	196.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DNTB@85009|Propionibacteriales	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HSJS3_k127_652412_1	1392502.JNIO01000008_gene2111	4.339e-14	75.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,4H2RW@909932|Negativicutes	909932|Negativicutes	M	NeuB family	-	-	-	-	-	-	-	-	-	-	-	-	NeuB,SAF
HSJS3_k127_652412_0	1459636.NTE_01706	5.473e-83	288.0	COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
HSJS3_k127_656827_1	459349.CLOAM0275	1.233e-26	128.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
HSJS3_k127_656827_0	292459.STH2792	2.59e-52	196.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,24BP1@186801|Clostridia	186801|Clostridia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
HSJS3_k127_6608438_0	326424.FRAAL5952	6.765e-56	202.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4ERM5@85013|Frankiales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HSJS3_k127_6608438_2	441620.Mpop_4837	1.302e-28	119.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,1JUJ9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	FG	PFAM histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HSJS3_k127_6608438_1	1170562.Cal6303_1797	1.766e-29	130.0	COG1459@1|root,COG1459@2|Bacteria,1G164@1117|Cyanobacteria,1HKUS@1161|Nostocales	1117|Cyanobacteria	U	PFAM Bacterial type II secretion system protein F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HSJS3_k127_6610065_3	237368.SCABRO_03229	1.187e-10	74.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Laminin_G_3,PKD,PPC,Phage-tail_3,Reprolysin_3,fn3
HSJS3_k127_6610065_2	477974.Daud_1771	3.554e-43	167.0	COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,24B0X@186801|Clostridia,264GQ@186807|Peptococcaceae	186801|Clostridia	M	Cytidylyltransferase	spsF	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
HSJS3_k127_6610065_1	871963.Desdi_0840	3.36e-83	290.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,26039@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HSJS3_k127_6610065_0	1209989.TepiRe1_1374	6.312e-133	430.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HSJS3_k127_6688221_1	1121374.KB891575_gene1478	7.049e-60	214.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
HSJS3_k127_6688221_0	1144275.COCOR_02445	1.127e-61	221.0	COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,42TUC@68525|delta/epsilon subdivisions,2WQGC@28221|Deltaproteobacteria,2YUIJ@29|Myxococcales	28221|Deltaproteobacteria	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
HSJS3_k127_6704972_1	1379858.N508_00613	7.783e-42	172.0	COG0750@1|root,COG0750@2|Bacteria,2GEXF@200930|Deferribacteres	200930|Deferribacteres	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
HSJS3_k127_6704972_2	1218108.KB908293_gene1207	0.0005346	44.0	2EMJ4@1|root,33F7P@2|Bacteria,4NYXT@976|Bacteroidetes,1I5IS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6704972_0	1136163.M565_ctg5P0465	7.614e-51	188.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,1XXKV@135623|Vibrionales	135623|Vibrionales	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HSJS3_k127_6728621_8	706587.Desti_0664	6.388e-36	145.0	COG1277@1|root,COG1277@2|Bacteria,1PK2D@1224|Proteobacteria,437V7@68525|delta/epsilon subdivisions,2WWIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
HSJS3_k127_6728621_10	665959.HMPREF1013_03652	2.962e-20	96.0	COG4314@1|root,COG4314@2|Bacteria,1V86E@1239|Firmicutes,4HJXZ@91061|Bacilli,1ZH53@1386|Bacillus	91061|Bacilli	C	NosL	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HSJS3_k127_6728621_7	1437824.BN940_13256	1.181e-39	161.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,3T2RB@506|Alcaligenaceae	28216|Betaproteobacteria	V	ATP-binding protein	nosF	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
HSJS3_k127_6728621_4	756499.Desde_0188	1.491e-77	284.0	COG3420@1|root,COG3420@2|Bacteria,1U542@1239|Firmicutes,24Z13@186801|Clostridia,264G0@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
HSJS3_k127_6728621_6	404589.Anae109_0245	1.29e-41	175.0	COG4314@1|root,COG4314@2|Bacteria,1R8N3@1224|Proteobacteria,42M7R@68525|delta/epsilon subdivisions,2WXID@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6728621_0	290397.Adeh_2402	1.32e-258	813.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,42P9D@68525|delta/epsilon subdivisions,2WTQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupredoxin_1
HSJS3_k127_6728621_3	404589.Anae109_0243	1.853e-127	420.0	COG2010@1|root,COG2010@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HSJS3_k127_6728621_2	290397.Adeh_2404	6.268e-159	513.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,2Z31Y@29|Myxococcales	28221|Deltaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
HSJS3_k127_6728621_5	404589.Anae109_0241	9.351e-44	165.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
HSJS3_k127_6728621_1	290397.Adeh_2406	4.627e-207	662.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
HSJS3_k127_6728621_9	1123371.ATXH01000004_gene1702	8.728e-26	112.0	COG1959@1|root,COG1959@2|Bacteria,2GI25@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HSJS3_k127_6740445_3	574087.Acear_1187	1.257e-08	60.0	COG0795@1|root,COG0795@2|Bacteria,1UZNX@1239|Firmicutes,24F8X@186801|Clostridia,3WAEC@53433|Halanaerobiales	186801|Clostridia	M	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HSJS3_k127_6740445_2	1123354.AUDR01000016_gene1392	1.735e-11	71.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,1KRSB@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RimP C-terminal SH3 domain	-	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HSJS3_k127_6740445_0	309799.DICTH_1081	4.081e-90	311.0	COG0195@1|root,COG0195@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600,ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021	-	-	-	KH_5,NusA_N,S1
HSJS3_k127_6740445_1	324602.Caur_3013	5.676e-26	121.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi,3753J@32061|Chloroflexia	32061|Chloroflexia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HSJS3_k127_6741481_0	382464.ABSI01000011_gene2323	0.0	1213.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
HSJS3_k127_6741481_3	880073.Calab_1256	1.433e-29	122.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HSJS3_k127_6741481_2	391587.KAOT1_02607	1.454e-74	265.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0008150,GO:0040007	4.2.1.113,5.1.1.20,5.1.1.3	ko:K01776,ko:K02549,ko:K19802	ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110	M00116	R00260,R04031,R10938	RC00302,RC01053,RC03309	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	iNJ661.Rv0553,iSB619.SA_RS09080	MR_MLE_C
HSJS3_k127_6741481_1	391587.KAOT1_02602	5.236e-124	412.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HSJS3_k127_6741979_0	1455608.JDTH01000001_gene3104	2.108e-06	61.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
HSJS3_k127_6747923_6	635013.TherJR_2733	1.922e-72	250.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,25ZXQ@186807|Peptococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HSJS3_k127_6747923_11	626887.J057_21695	3.301e-25	123.0	COG3291@1|root,COG3291@2|Bacteria,1MWIT@1224|Proteobacteria,1S1VQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,PKD
HSJS3_k127_6747923_10	287986.DV20_41760	1.811e-39	154.0	COG1670@1|root,COG1670@2|Bacteria,2I90W@201174|Actinobacteria,4E38Y@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HSJS3_k127_6747923_2	1116375.VEJY3_20506	9.712e-174	557.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria,1XW0M@135623|Vibrionales	135623|Vibrionales	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
HSJS3_k127_6747923_4	76114.ebA6736	2.316e-126	421.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
HSJS3_k127_6747923_5	1121468.AUBR01000012_gene2582	2.527e-120	399.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,42F8F@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HSJS3_k127_6747923_9	1196028.ALEF01000053_gene3522	6.519e-52	204.0	COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,4C5G9@84406|Virgibacillus	91061|Bacilli	E	Peptidase family M20/M25/M40	rocB	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M20
HSJS3_k127_6747923_1	382464.ABSI01000010_gene3794	1.446e-177	600.0	COG4888@1|root,COG4888@2|Bacteria,46UDG@74201|Verrucomicrobia	2|Bacteria	O	PFAM ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HSJS3_k127_6747923_3	941824.TCEL_01253	6.921e-150	484.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,36DDF@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HSJS3_k127_6747923_8	293826.Amet_2777	3.13e-53	196.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,36EV9@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HSJS3_k127_6747923_12	67267.JNXT01000062_gene7349	1.83e-17	94.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HSJS3_k127_6747923_13	946483.Cenrod_1115	8.724e-09	66.0	COG2340@1|root,COG2340@2|Bacteria,1R9R3@1224|Proteobacteria,2VPPC@28216|Betaproteobacteria,4AJTX@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Allergen V5 Tpx-1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	CAP
HSJS3_k127_6747923_7	643648.Slip_0629	1.648e-68	254.0	COG1808@1|root,COG1808@2|Bacteria,1TRFZ@1239|Firmicutes,24PYJ@186801|Clostridia	186801|Clostridia	S	Hydrophobic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
HSJS3_k127_6747923_0	1347392.CCEZ01000010_gene2379	1.147e-253	807.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HSJS3_k127_6747923_14	1391647.AVSV01000016_gene921	3.24e-08	64.0	COG1376@1|root,COG1376@2|Bacteria,1V9CP@1239|Firmicutes,25B2P@186801|Clostridia,36EB4@31979|Clostridiaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HSJS3_k127_6758853_4	768066.HELO_1427	5.275e-52	184.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XI9V@135619|Oceanospirillales	135619|Oceanospirillales	P	Sodium proton antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
HSJS3_k127_6758853_5	1397528.Q671_09620	5.738e-45	169.0	COG0226@1|root,COG0226@2|Bacteria,1N19C@1224|Proteobacteria,1SEQX@1236|Gammaproteobacteria,1XM1Q@135619|Oceanospirillales	135619|Oceanospirillales	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6758853_1	1504981.KO116_3176	2.897e-220	692.0	COG3203@1|root,COG3203@2|Bacteria,1PJNW@1224|Proteobacteria,1RZXJ@1236|Gammaproteobacteria,1XIW3@135619|Oceanospirillales	135619|Oceanospirillales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6758853_0	1380358.JADJ01000005_gene2709	0.0	1394.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XISY@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,dCache_3
HSJS3_k127_6758853_6	187272.Mlg_0150	1.581e-44	171.0	COG3916@1|root,COG3916@2|Bacteria,1RCQC@1224|Proteobacteria,1S3K2@1236|Gammaproteobacteria,1WYXI@135613|Chromatiales	135613|Chromatiales	QT	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
HSJS3_k127_6758853_2	42565.FP66_01050	9.224e-151	485.0	29HQP@1|root,30M4I@2|Bacteria,1RDRF@1224|Proteobacteria,1SNBJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3541)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3541
HSJS3_k127_6758853_3	1397528.Q671_09655	1.011e-96	321.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,1XJ7A@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
HSJS3_k127_6759863_1	1449048.JQKU01000005_gene4748	0.0002914	53.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria,237GJ@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
HSJS3_k127_6759863_0	635013.TherJR_2842	1.086e-92	313.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia,260IV@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HSJS3_k127_6776319_2	1047013.AQSP01000122_gene2224	2.057e-17	95.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
HSJS3_k127_6776319_0	340099.Teth39_1816	1.274e-58	224.0	COG2610@1|root,COG2610@2|Bacteria,1UIHX@1239|Firmicutes,25EYC@186801|Clostridia,42J6S@68295|Thermoanaerobacterales	186801|Clostridia	EG	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
HSJS3_k127_6776319_1	631362.Thi970DRAFT_01394	9.99e-21	98.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1WY14@135613|Chromatiales	135613|Chromatiales	T	PFAM Phosphoglycerate mutase	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
HSJS3_k127_6796948_0	204669.Acid345_3828	1.174e-44	177.0	COG3303@1|root,COG3303@2|Bacteria,3Y999@57723|Acidobacteria,2JP5G@204432|Acidobacteriia	204432|Acidobacteriia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
HSJS3_k127_6796948_2	521095.Apar_1097	0.0001162	54.0	COG0457@1|root,COG0457@2|Bacteria	521095.Apar_1097|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6814360_0	1121104.AQXH01000005_gene210	4.46e-127	412.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HSJS3_k127_6814360_2	445971.ANASTE_01225	2.841e-44	169.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,25VIM@186806|Eubacteriaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HSJS3_k127_6814360_5	477974.Daud_0971	0.0003824	50.0	COG4970@1|root,COG4970@2|Bacteria,1U4QW@1239|Firmicutes,25IDV@186801|Clostridia,266MB@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM general secretion pathway protein H	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	N_methyl
HSJS3_k127_6814360_4	177437.HRM2_27670	1.79e-05	53.0	COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,42X6W@68525|delta/epsilon subdivisions,2WSY4@28221|Deltaproteobacteria,2MMCT@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458,ko:K02671	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	N_methyl
HSJS3_k127_6814360_3	262724.TT_P0078	5.499e-24	118.0	COG3156@1|root,COG3156@2|Bacteria,1WJH7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	type II secretion system protein K	-	-	-	-	-	-	-	-	-	-	-	-	DUF4900,PilX_N
HSJS3_k127_6814360_1	326297.Sama_2476	7.043e-115	384.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,2QAFD@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	PFAM type II secretion system protein E	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HSJS3_k127_6850678_0	552398.HMPREF0866_02094	4.972e-19	100.0	COG0438@1|root,COG2327@1|root,COG0438@2|Bacteria,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,3WHHB@541000|Ruminococcaceae	186801|Clostridia	M	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
HSJS3_k127_689763_0	661478.OP10G_0240	1.644e-42	171.0	COG1626@1|root,COG1626@2|Bacteria	2|Bacteria	G	alpha,alpha-trehalase activity	ygjK	GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716	3.2.1.28	ko:K01194,ko:K03931	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37,GH63	-	Glyco_hydro_63,Trehalase
HSJS3_k127_6901994_1	1121924.ATWH01000031_gene3643	1.241e-07	65.0	COG3401@1|root,COG3401@2|Bacteria,2GMCU@201174|Actinobacteria,4FN94@85023|Microbacteriaceae	201174|Actinobacteria	E	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HSJS3_k127_6901994_0	399550.Smar_0589	1.033e-08	69.0	arCOG02559@1|root,arCOG05978@1|root,arCOG02559@2157|Archaea,arCOG05978@2157|Archaea	2157|Archaea	C	Fibronectin type III domain protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	DUF5122,PEGA,Pkinase,fn3
HSJS3_k127_6903742_0	1089553.Tph_c09750	1.371e-66	241.0	COG0530@1|root,COG0530@2|Bacteria,1UE3Y@1239|Firmicutes,25IY9@186801|Clostridia,42F30@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HSJS3_k127_6903742_1	469381.Dpep_1570	4.636e-66	250.0	COG3426@1|root,COG3426@2|Bacteria,3T9TY@508458|Synergistetes	508458|Synergistetes	H	Belongs to the acetokinase family	-	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
HSJS3_k127_6903742_3	1391647.AVSV01000034_gene410	1.212e-42	178.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,36DC6@31979|Clostridiaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747,GO:0050182	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
HSJS3_k127_6903742_2	1174528.JH992898_gene5196	1.684e-43	170.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1G36D@1117|Cyanobacteria,1JK64@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_6903742_4	688269.Theth_1398	1.257e-37	145.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
HSJS3_k127_6907330_1	592029.DDD_1606	2.93e-23	103.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1HWSY@117743|Flavobacteriia,3HK5E@363408|Nonlabens	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HSJS3_k127_6907330_3	69328.PVLB_03560	0.0009458	48.0	COG0346@1|root,COG0346@2|Bacteria,1RKEC@1224|Proteobacteria,1S79I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HSJS3_k127_6907330_0	86416.Clopa_1260	1.739e-24	114.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,36EPM@31979|Clostridiaceae	186801|Clostridia	I	Lipid kinase	dagK	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
HSJS3_k127_6907330_2	1288494.EBAPG3_2530	0.0001727	45.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,372X4@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HSJS3_k127_6924738_0	546271.Selsp_0877	4.881e-217	693.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4H20K@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HSJS3_k127_6924738_3	1122223.KB890688_gene1569	1.811e-30	130.0	COG0746@1|root,COG0746@2|Bacteria,1WNGF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
HSJS3_k127_6924738_1	203119.Cthe_2174	1.262e-137	456.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,3WGZQ@541000|Ruminococcaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HSJS3_k127_6924738_2	886293.Sinac_1816	3.973e-81	289.0	COG2304@1|root,COG2304@2|Bacteria,2IY1T@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA,VWA_3
HSJS3_k127_6933318_3	1231190.NA8A_00250	3.022e-31	124.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,43NHA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HSJS3_k127_6933318_1	1379270.AUXF01000001_gene1861	5.875e-54	219.0	COG1404@1|root,COG2247@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.4.24.3	ko:K01387,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Peptidase_S8,SLH
HSJS3_k127_6933318_4	1536775.H70737_09395	2.527e-07	65.0	COG0366@1|root,COG4099@1|root,COG5492@1|root,COG0366@2|Bacteria,COG4099@2|Bacteria,COG5492@2|Bacteria,1TRE3@1239|Firmicutes,4HD4N@91061|Bacilli,26QR2@186822|Paenibacillaceae	91061|Bacilli	GN	Glycosyl hydrolase 101 beta sandwich domain	-	-	3.2.1.97	ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,Big_4,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,Gram_pos_anchor,Trypsin_2,YSIRK_signal
HSJS3_k127_6933318_2	927677.ALVU02000001_gene1740	8.356e-37	145.0	COG0671@1|root,COG0671@2|Bacteria,1G63X@1117|Cyanobacteria	1117|Cyanobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HSJS3_k127_6933318_0	338966.Ppro_3650	0.0	1063.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,43U5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
HSJS3_k127_6935993_5	933801.Ahos_2012	1.579e-12	78.0	COG0243@1|root,arCOG01491@2157|Archaea,2XPYH@28889|Crenarchaeota	28889|Crenarchaeota	C	Formate dehydrogenase Alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
HSJS3_k127_6935993_1	570967.JMLV01000005_gene89	2.409e-86	299.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,2JPWU@204441|Rhodospirillales	204441|Rhodospirillales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HSJS3_k127_6935993_2	1120950.KB892779_gene963	8.784e-38	147.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4DP1W@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
HSJS3_k127_6935993_4	1218108.KB908293_gene1339	2.078e-20	99.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I32F@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HSJS3_k127_6935993_3	237368.SCABRO_02000	6.407e-25	107.0	COG0713@1|root,COG0713@2|Bacteria,2J0GU@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HSJS3_k127_6935993_0	316067.Geob_0473	4.925e-97	328.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,43TW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
HSJS3_k127_6951143_1	243233.MCA2132	0.0006046	44.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XGD1@135618|Methylococcales	135618|Methylococcales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HSJS3_k127_6951143_0	13035.Dacsa_1230	1.951e-286	915.0	COG0841@1|root,COG0841@2|Bacteria,1G21T@1117|Cyanobacteria	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HSJS3_k127_6982236_1	330214.NIDE0848	4.205e-48	186.0	COG0755@1|root,COG0755@2|Bacteria,3J0NY@40117|Nitrospirae	40117|Nitrospirae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
HSJS3_k127_6982236_0	1123253.AUBD01000007_gene664	9.334e-54	197.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1X32M@135614|Xanthomonadales	135614|Xanthomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HSJS3_k127_6982236_2	586413.CCDL010000002_gene2544	5.944e-20	100.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,23KFX@182709|Oceanobacillus	91061|Bacilli	MU	Signal peptidase (SPase) II	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HSJS3_k127_6982236_3	1382306.JNIM01000001_gene239	1.73e-10	66.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	ysfE	-	2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5	ko:K00941,ko:K01724,ko:K01759,ko:K07032,ko:K08234	ko00620,ko00730,ko00790,ko01100,map00620,map00730,map00790,map01100	M00127	R02530,R03471,R04509,R04734	RC00002,RC00004,RC00017,RC00740,RC01208	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
HSJS3_k127_7028669_3	330214.NIDE4368	1.152e-28	123.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
HSJS3_k127_7028669_2	693661.Arcve_0846	8.216e-101	353.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,245T6@183980|Archaeoglobi	183980|Archaeoglobi	J	phenylalanyl-tRNA synthetase, beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
HSJS3_k127_7028669_1	945713.IALB_0211	9.228e-103	348.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HSJS3_k127_7028669_0	649638.Trad_2595	2.494e-107	363.0	COG1494@1|root,COG1494@2|Bacteria,1WI3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
HSJS3_k127_7052424_1	1125863.JAFN01000001_gene1966	2.049e-11	74.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria	1224|Proteobacteria	U	Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HSJS3_k127_7052424_0	555088.DealDRAFT_1051	2.173e-82	278.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,42JMV@68298|Syntrophomonadaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HSJS3_k127_7065856_1	1071073.KI530537_gene2356	8.105e-68	235.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HSJS3_k127_7065856_2	1089553.Tph_c12690	1.421e-61	228.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,24948@186801|Clostridia,42ERM@68295|Thermoanaerobacterales	186801|Clostridia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
HSJS3_k127_7065856_3	411467.BACCAP_03884	1.466e-50	193.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,267K5@186813|unclassified Clostridiales	186801|Clostridia	M	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HSJS3_k127_7065856_0	56780.SYN_01747	1.3e-101	348.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MR03@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_7065856_5	1125863.JAFN01000001_gene3162	9.92e-12	78.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N9Y@68525|delta/epsilon subdivisions,2WM7D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HSJS3_k127_7065856_4	888727.HMPREF9092_1267	2.592e-27	119.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,3WCD5@538999|Clostridiales incertae sedis	186801|Clostridia	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HSJS3_k127_7102673_2	43151.ADAC010096-PA	6.37e-22	110.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,41TPQ@6656|Arthropoda,3SGZ4@50557|Insecta,44XMY@7147|Diptera,45BV2@7148|Nematocera	33208|Metazoa	W	TIR domain	SARM1	GO:0002682,GO:0002683,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005856,GO:0005874,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0009611,GO:0009743,GO:0009746,GO:0009749,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010769,GO:0010941,GO:0010975,GO:0015630,GO:0016020,GO:0019867,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030424,GO:0030425,GO:0031090,GO:0031312,GO:0031315,GO:0031344,GO:0031347,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0034121,GO:0034122,GO:0034127,GO:0034128,GO:0034284,GO:0036477,GO:0042221,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043067,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045088,GO:0045202,GO:0045595,GO:0045664,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048678,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051716,GO:0051960,GO:0060284,GO:0065007,GO:0080134,GO:0097447,GO:0097458,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_7102673_1	994479.GL877883_gene7373	1.12e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2IIK3@201174|Actinobacteria,4E2YS@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
HSJS3_k127_7102673_0	1479237.JMLY01000001_gene3533	1.358e-56	202.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,465AD@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HSJS3_k127_7132658_0	745310.G432_08280	5.226e-10	60.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K27R@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HSJS3_k127_7151305_0	1379698.RBG1_1C00001G0875	1.487e-87	300.0	COG3958@1|root,COG3958@2|Bacteria,2NQFH@2323|unclassified Bacteria	2|Bacteria	G	Transketolase, pyrimidine binding domain	tktC	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HSJS3_k127_7151305_1	1449126.JQKL01000014_gene2986	2.226e-76	269.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,267Z6@186813|unclassified Clostridiales	186801|Clostridia	G	Dehydrogenase E1 component	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HSJS3_k127_7177552_4	944480.ATUV01000001_gene759	4.544e-43	171.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,2M6YP@213113|Desulfurellales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HSJS3_k127_7177552_2	1232410.KI421419_gene2479	2.005e-50	195.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,43S9I@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HSJS3_k127_7177552_3	1869.MB27_35525	2.933e-48	189.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4D8TU@85008|Micromonosporales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
HSJS3_k127_7177552_1	1379698.RBG1_1C00001G0215	1.341e-57	216.0	COG0577@1|root,COG0577@2|Bacteria,2NP20@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HSJS3_k127_7177552_0	1232410.KI421419_gene2479	8.201e-83	292.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,43S9I@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HSJS3_k127_7177552_5	1539298.JO41_05990	2.293e-30	132.0	COG0274@1|root,COG0274@2|Bacteria,2J7GA@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HSJS3_k127_7200537_5	570952.ATVH01000015_gene1531	5.785e-17	90.0	COG3650@1|root,COG3650@2|Bacteria	2|Bacteria	CO	response to hydrogen peroxide	-	-	-	ko:K08985	-	-	-	-	ko00000	-	-	-	-
HSJS3_k127_7200537_4	882083.SacmaDRAFT_2449	3.564e-17	89.0	COG0491@1|root,COG0491@2|Bacteria,2IA2U@201174|Actinobacteria,4EB08@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HSJS3_k127_7200537_2	1131269.AQVV01000005_gene388	3.63e-54	203.0	COG3639@1|root,COG3639@2|Bacteria	2|Bacteria	P	organic phosphonate transmembrane transporter activity	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
HSJS3_k127_7200537_1	562970.Btus_3107	5.457e-75	259.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,2789Q@186823|Alicyclobacillaceae	91061|Bacilli	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
HSJS3_k127_7200537_3	1121912.AUHD01000006_gene1332	6.72e-21	94.0	COG3360@1|root,COG3360@2|Bacteria,4NURJ@976|Bacteroidetes,1I534@117743|Flavobacteriia	976|Bacteroidetes	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
HSJS3_k127_7200537_6	1040986.ATYO01000040_gene5625	2.355e-16	87.0	COG1595@1|root,COG1595@2|Bacteria,1RFN0@1224|Proteobacteria,2U8N2@28211|Alphaproteobacteria,43K4S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_7200537_0	533247.CRD_01959	6.343e-122	402.0	COG0516@1|root,COG0516@2|Bacteria,1G1MX@1117|Cyanobacteria,1HJDQ@1161|Nostocales	1117|Cyanobacteria	F	PFAM IMP dehydrogenase GMP reductase	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
HSJS3_k127_72138_0	1280679.ATVX01000001_gene2744	2.803e-58	213.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,4BXKA@830|Butyrivibrio	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HSJS3_k127_72138_1	1123389.ATXJ01000004_gene1285	3.182e-48	186.0	COG2355@1|root,COG2355@2|Bacteria,1WJQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HSJS3_k127_7235074_1	644966.Tmar_1417	1.218e-65	234.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3WCV0@538999|Clostridiales incertae sedis	186801|Clostridia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HSJS3_k127_7235074_0	981383.AEWH01000018_gene3243	1.107e-108	368.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HSJS3_k127_7235074_2	1168034.FH5T_05985	1.271e-20	97.0	29X2D@1|root,30IQV@2|Bacteria,4NPC2@976|Bacteroidetes	976|Bacteroidetes	S	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
HSJS3_k127_7235358_1	387631.Asulf_00521	0.0002652	55.0	COG3979@1|root,COG5306@1|root,arCOG02420@1|root,arCOG03511@1|root,arCOG03553@1|root,arCOG09173@1|root,arCOG02420@2157|Archaea,arCOG03508@2157|Archaea,arCOG03511@2157|Archaea,arCOG03553@2157|Archaea,arCOG07581@2157|Archaea,arCOG09173@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF2341,PKD,Pilin_N,S_layer_C
HSJS3_k127_7235358_0	446470.Snas_4577	4.481e-16	78.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EZDX@85014|Glycomycetales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K13315	ko00523,ko01130,map00523,map01130	M00798,M00799	R11051,R11474	RC00897,RC01516	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
HSJS3_k127_7310766_2	1313304.CALK_1933	7.599e-36	154.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,HDOD,PAS_3,PAS_4,PilJ
HSJS3_k127_7310766_3	553171.HMPREF0648_0563	4.549e-05	54.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,2FPHH@200643|Bacteroidia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HSJS3_k127_7310766_1	1499689.CCNN01000015_gene3399	8.201e-83	292.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,36F3M@31979|Clostridiaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HSJS3_k127_7310766_0	596315.HMPREF0634_0656	8.088e-147	477.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25QN3@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HSJS3_k127_7487386_0	1157490.EL26_04050	1.943e-63	230.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,279QT@186823|Alicyclobacillaceae	91061|Bacilli	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
HSJS3_k127_7490221_0	1307761.L21SP2_3229	3.467e-08	60.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HSJS3_k127_7576251_1	67352.JODS01000015_gene7029	5.045e-42	166.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HSJS3_k127_7576251_0	1156937.MFUM_830011	8.996e-82	285.0	COG1363@1|root,COG1363@2|Bacteria,46SM3@74201|Verrucomicrobia,37FYC@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HSJS3_k127_7593147_2	1194972.MVAC_15083	9.483e-05	55.0	COG3391@1|root,COG4932@1|root,COG3391@2|Bacteria,COG4932@2|Bacteria,2GK45@201174|Actinobacteria,2366T@1762|Mycobacteriaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Lactonase
HSJS3_k127_7593147_0	649638.Trad_2559	2.409e-28	120.0	COG1607@1|root,COG1607@2|Bacteria,1WJZ4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM thioesterase superfamily	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
HSJS3_k127_7593147_1	941824.TCEL_00162	3.912e-25	108.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,36DQF@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HSJS3_k127_7622291_2	479434.Sthe_1030	6.334e-59	217.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,27Y0B@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HSJS3_k127_7622291_3	580332.Slit_1271	5.642e-58	217.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
HSJS3_k127_7622291_1	903818.KI912268_gene1621	7.724e-60	215.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	yafV	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0044464,GO:0050152,GO:0071944,GO:0106008	3.5.1.3,3.5.1.77,3.5.5.1	ko:K01459,ko:K01501,ko:K11206,ko:K13566	ko00250,ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00250,map00380,map00460,map00627,map00643,map00910,map01120	-	R00269,R00348,R00540,R01887,R03093,R03542,R05591,R07855	RC00010,RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,CN_hydrolase
HSJS3_k127_7622291_5	883078.HMPREF9695_02297	4.814e-32	130.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2U922@28211|Alphaproteobacteria,3JY6M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
HSJS3_k127_7622291_6	448385.sce4803	2.558e-18	93.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales	28221|Deltaproteobacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
HSJS3_k127_7622291_4	443143.GM18_4316	3.092e-41	171.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
HSJS3_k127_7622291_0	207559.Dde_1854	3.864e-119	394.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42MUA@68525|delta/epsilon subdivisions,2WJWH@28221|Deltaproteobacteria,2MAFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex,PGPGW
HSJS3_k127_7622291_7	1296416.JACB01000031_gene2565	1.187e-05	56.0	COG0526@1|root,COG0526@2|Bacteria,4NNU2@976|Bacteroidetes,1I22P@117743|Flavobacteriia,2YHTN@290174|Aquimarina	976|Bacteroidetes	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HSJS3_k127_7674452_4	1195236.CTER_3705	0.0004646	47.0	COG0726@1|root,COG4193@1|root,COG0726@2|Bacteria,COG4193@2|Bacteria,1TT17@1239|Firmicutes,24CQR@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 11 (cellulase G) family	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_6,Dockerin_1,Glyco_hydro_10,Glyco_hydro_11,Polysacc_deac_1
HSJS3_k127_7674452_2	243365.CV_3741	1.541e-13	79.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,2KQ9Z@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
HSJS3_k127_7674452_0	439235.Dalk_4469	3.445e-33	136.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2X5P3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HSJS3_k127_7674452_1	396588.Tgr7_0462	1.414e-14	83.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,1S3GT@1236|Gammaproteobacteria,1X151@135613|Chromatiales	135613|Chromatiales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_7674452_3	300852.55771385	0.0002839	44.0	COG0469@1|root,COG0469@2|Bacteria,1WJAC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the pyruvate kinase family	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HSJS3_k127_7778302_8	300852.55773110	4.003e-06	56.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	2|Bacteria	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	dsbE	-	-	ko:K02199,ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
HSJS3_k127_7778302_9	536233.CLO_0840	0.0002859	50.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,249IS@186801|Clostridia,36FFI@31979|Clostridiaceae	186801|Clostridia	O	Cytochrome c biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD,Redoxin
HSJS3_k127_7778302_6	1034347.CAHJ01000084_gene1356	2.821e-33	134.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,1ZGAT@1386|Bacillus	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
HSJS3_k127_7778302_7	926561.KB900620_gene3036	1.269e-07	61.0	2DYM3@1|root,34AAK@2|Bacteria,1VZ8W@1239|Firmicutes,25JGS@186801|Clostridia,3WC03@53433|Halanaerobiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7778302_0	1210884.HG799465_gene12267	2.32e-99	345.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,CarboxypepD_reg,IAT_beta,Invasin_D3,PPC
HSJS3_k127_7778302_3	671143.DAMO_0351	2.5e-55	200.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7778302_2	671143.DAMO_0350	2.341e-62	224.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7778302_4	247490.KSU1_B0649	5.571e-51	189.0	29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7778302_1	247490.KSU1_B0650	2.961e-94	330.0	28MEN@1|root,2ZASA@2|Bacteria,2IZ1H@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7778302_5	344747.PM8797T_23696	2.328e-50	182.0	28II6@1|root,2Z8JB@2|Bacteria,2IXG8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_7950006_0	1209989.TepiRe1_0743	3.485e-207	669.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
HSJS3_k127_7950006_1	330214.NIDE2542	1.137e-63	226.0	COG0505@1|root,COG0505@2|Bacteria,3J0CS@40117|Nitrospirae	40117|Nitrospirae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HSJS3_k127_8026206_2	1121035.AUCH01000012_gene3023	3.025e-53	196.0	COG0501@1|root,COG0501@2|Bacteria,1NG7Y@1224|Proteobacteria	1224|Proteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HSJS3_k127_8026206_0	1469607.KK073765_gene6639	9.974e-102	336.0	COG2370@1|root,COG2370@2|Bacteria,1G65K@1117|Cyanobacteria	1117|Cyanobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
HSJS3_k127_8026206_1	228410.NE0543	1.917e-64	226.0	293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,2VSIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8056345_0	1121930.AQXG01000005_gene666	3.807e-49	184.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1IQGT@117747|Sphingobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HSJS3_k127_8110875_1	641524.ADICYQ_3871	1.719e-146	473.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS3_k127_8110875_3	1303518.CCALI_02162	7.869e-60	219.0	COG0548@1|root,COG0548@2|Bacteria	2|Bacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784	AA_kinase
HSJS3_k127_8110875_2	886379.AEWI01000033_gene2743	1.776e-84	293.0	COG3457@1|root,COG3457@2|Bacteria,4NFEJ@976|Bacteroidetes,2FWAC@200643|Bacteroidia,3XKPC@558415|Marinilabiliaceae	976|Bacteroidetes	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
HSJS3_k127_8110875_4	403833.Pmob_1650	1.261e-36	144.0	COG0454@1|root,COG0456@2|Bacteria,2GE5M@200918|Thermotogae	200918|Thermotogae	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8110875_0	517417.Cpar_1399	1.302e-180	578.0	COG0591@1|root,COG0591@2|Bacteria,1FEER@1090|Chlorobi	1090|Chlorobi	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HSJS3_k127_8113947_2	903818.KI912269_gene301	3.835e-49	184.0	COG0002@1|root,COG0002@2|Bacteria,3Y450@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HSJS3_k127_8113947_1	378806.STAUR_5874	3.827e-105	356.0	COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria,438QP@68525|delta/epsilon subdivisions,2X92A@28221|Deltaproteobacteria,2YXIK@29|Myxococcales	28221|Deltaproteobacteria	H	Domain of unknown function (DUF1611_C) P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611
HSJS3_k127_8113947_0	1121920.AUAU01000010_gene47	1.622e-130	429.0	COG0137@1|root,COG0137@2|Bacteria,3Y4Y9@57723|Acidobacteria	57723|Acidobacteria	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HSJS3_k127_8139188_0	1056512.D515_01852	3.484e-165	532.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1Y01B@135623|Vibrionales	135623|Vibrionales	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
HSJS3_k127_8147046_0	502025.Hoch_5710	1.084e-113	383.0	COG0490@1|root,COG1226@1|root,COG4651@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,2YX01@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
HSJS3_k127_818916_0	1123288.SOV_4c01930	1.467e-29	124.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H437@909932|Negativicutes	909932|Negativicutes	S	Peptidase M50	spoIVFB	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HSJS3_k127_818916_1	517417.Cpar_0091	2.769e-27	119.0	COG1354@1|root,COG1354@2|Bacteria,1FD8J@1090|Chlorobi	1090|Chlorobi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HSJS3_k127_8196517_2	1068980.ARVW01000001_gene1045	6.773e-05	51.0	COG3832@1|root,COG3832@2|Bacteria,2GNVY@201174|Actinobacteria,4E2JC@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HSJS3_k127_8196517_1	1122611.KB903963_gene4803	1.505e-39	154.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4EI7R@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HSJS3_k127_8196517_0	243164.DET1216	1.219e-43	169.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi,34CKY@301297|Dehalococcoidia	301297|Dehalococcoidia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
HSJS3_k127_82358_0	1499967.BAYZ01000139_gene142	1.581e-45	184.0	COG1216@1|root,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HSJS3_k127_82358_1	435590.BVU_3961	3.373e-15	89.0	COG1216@1|root,COG1216@2|Bacteria,4NEJB@976|Bacteroidetes,2FMB7@200643|Bacteroidia,4AKPW@815|Bacteroidaceae	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HSJS3_k127_8264524_1	439235.Dalk_2289	3.65e-25	122.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
HSJS3_k127_8264524_3	1123401.JHYQ01000037_gene1613	1.162e-05	59.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	atl	-	3.2.1.96,3.5.1.28	ko:K13714	-	-	-	-	ko00000,ko01000	-	GH73	-	Glucosaminidase,Gram_pos_anchor,SH3_8,SPOR,YSIRK_signal
HSJS3_k127_8264524_2	1280001.BAOA01000205_gene1301	4.043e-07	64.0	COG3266@1|root,COG3266@2|Bacteria,1R230@1224|Proteobacteria,1T60F@1236|Gammaproteobacteria,1XZHC@135623|Vibrionales	1224|Proteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8264524_0	1121924.ATWH01000001_gene4299	1.025e-34	155.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
HSJS3_k127_8291096_2	382464.ABSI01000005_gene1147	9.503e-15	86.0	COG1538@1|root,COG1538@2|Bacteria,46VZS@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HSJS3_k127_8291096_0	1304284.L21TH_0519	8.165e-97	324.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,36DXW@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HSJS3_k127_8291096_1	1267533.KB906734_gene4069	1.067e-63	228.0	COG0179@1|root,COG0179@2|Bacteria,3Y30T@57723|Acidobacteria,2JJ0G@204432|Acidobacteriia	204432|Acidobacteriia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HSJS3_k127_8380572_2	1267535.KB906767_gene3809	5.699e-16	86.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3809|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8380572_0	1125863.JAFN01000001_gene2804	2.397e-121	406.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HSJS3_k127_8380572_1	1089553.Tph_c28850	7.077e-82	288.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,42H8N@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HSJS3_k127_8390532_7	1408423.JHYA01000012_gene1539	1.472e-16	91.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,4H2PV@909932|Negativicutes	909932|Negativicutes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HSJS3_k127_8390532_5	321332.CYB_2385	4.389e-20	105.0	COG0795@1|root,COG0795@2|Bacteria,1G14H@1117|Cyanobacteria,1GZDN@1129|Synechococcus	1117|Cyanobacteria	S	Permease, YjgP YjgQ family	ycf84	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HSJS3_k127_8390532_2	289376.THEYE_A0840	6.396e-29	129.0	COG4783@1|root,COG4783@2|Bacteria,3J19Q@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HSJS3_k127_8390532_1	518766.Rmar_0090	2.263e-51	192.0	COG1842@1|root,COG1842@2|Bacteria,4P0T5@976|Bacteroidetes,1FIR5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
HSJS3_k127_8390532_8	880526.KE386488_gene91	4.444e-11	65.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,2FUJ7@200643|Bacteroidia,22UK2@171550|Rikenellaceae	976|Bacteroidetes	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HSJS3_k127_8390532_9	1382356.JQMP01000003_gene1811	1.735e-09	64.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,27YJ4@189775|Thermomicrobia	189775|Thermomicrobia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HSJS3_k127_8390532_4	521045.Kole_0256	7.059e-24	103.0	COG0759@1|root,COG0759@2|Bacteria,2GD8E@200918|Thermotogae	200918|Thermotogae	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HSJS3_k127_8390532_6	469381.Dpep_2016	1.261e-19	102.0	COG0706@1|root,COG0706@2|Bacteria,3T9Q5@508458|Synergistetes	508458|Synergistetes	U	Membrane protein insertase, YidC Oxa1 family	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HSJS3_k127_8390532_10	1128421.JAGA01000004_gene2577	2.424e-09	66.0	COG1847@1|root,COG1847@2|Bacteria,2NQ3F@2323|unclassified Bacteria	2|Bacteria	S	Jag_N	jag	-	-	ko:K06346,ko:K09749	-	-	-	-	ko00000	-	-	-	KH_4,R3H
HSJS3_k127_8390532_13	880074.BARVI_13045	0.0003851	45.0	COG1983@1|root,COG1983@2|Bacteria,4NX1N@976|Bacteroidetes,2FUW2@200643|Bacteroidia,22YYQ@171551|Porphyromonadaceae	976|Bacteroidetes	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
HSJS3_k127_8390532_0	269799.Gmet_0135	1.863e-82	293.0	COG1109@1|root,COG1109@2|Bacteria,1R96J@1224|Proteobacteria,42PM2@68525|delta/epsilon subdivisions,2WKSP@28221|Deltaproteobacteria,43T3P@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HSJS3_k127_8390532_3	414996.IL38_01740	9.184e-25	107.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4094P@622450|Actinopolysporales	201174|Actinobacteria	O	Thioredoxin-like domain	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HSJS3_k127_8390532_12	317619.ANKN01000183_gene272	0.0002347	52.0	COG0170@1|root,COG0170@2|Bacteria,1GC2P@1117|Cyanobacteria,1MMFV@1212|Prochloraceae	1117|Cyanobacteria	I	Alternative locus ID	sec59	-	2.7.1.182	ko:K18678	-	-	R10659	RC00002,RC00017	ko00000,ko01000	-	-	-	-
HSJS3_k127_8390532_11	375451.RD1_4207	6.072e-05	55.0	COG1083@1|root,COG3980@1|root,COG1083@2|Bacteria,COG3980@2|Bacteria,1QACI@1224|Proteobacteria,2U5PV@28211|Alphaproteobacteria,2P3R2@2433|Roseobacter	28211|Alphaproteobacteria	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
HSJS3_k127_8392989_3	1043493.BBLU01000001_gene1056	2.263e-14	81.0	COG0840@1|root,COG0840@2|Bacteria,2IEV7@201174|Actinobacteria	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_2
HSJS3_k127_8392989_1	1244869.H261_01102	5.285e-45	171.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria	1224|Proteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
HSJS3_k127_8392989_0	349521.HCH_02328	2.386e-54	213.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1XR34@135619|Oceanospirillales	135619|Oceanospirillales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
HSJS3_k127_8392989_6	2423.NA23_0204925	3.782e-06	60.0	COG4254@1|root,COG4254@2|Bacteria,2GD0Z@200918|Thermotogae	200918|Thermotogae	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
HSJS3_k127_8392989_5	796940.HMPREF9628_00517	9.119e-09	59.0	COG0333@1|root,COG0333@2|Bacteria,1UEFG@1239|Firmicutes,25JCA@186801|Clostridia,25RXJ@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal L32p protein family	-	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HSJS3_k127_8392989_2	82654.Pse7367_0764	2.443e-18	87.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria,1HCZT@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HSJS3_k127_8392989_4	1484479.DI14_01265	8.379e-12	72.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,4HPRP@91061|Bacilli,3WFSU@539002|Bacillales incertae sedis	91061|Bacilli	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ytlP	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
HSJS3_k127_8457043_0	1158604.I591_01408	4.113e-45	178.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,4B0SI@81852|Enterococcaceae	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HSJS3_k127_8565793_1	439235.Dalk_2289	9.062e-66	254.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
HSJS3_k127_8565793_0	1033734.CAET01000082_gene3407	5.484e-104	355.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
HSJS3_k127_8565793_2	1303518.CCALI_02276	1.414e-64	226.0	COG0462@1|root,COG0462@2|Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
HSJS3_k127_8604982_1	945713.IALB_1358	1.566e-23	105.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HSJS3_k127_8604982_2	290512.Paes_0560	1.942e-11	69.0	COG0848@1|root,COG0848@2|Bacteria,1FFFC@1090|Chlorobi	1090|Chlorobi	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
HSJS3_k127_8604982_0	697281.Mahau_1050	2.391e-58	205.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HSJS3_k127_8663820_1	929703.KE386491_gene756	2.769e-27	119.0	COG2866@1|root,COG2866@2|Bacteria,4NHBS@976|Bacteroidetes,47MR4@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HSJS3_k127_8663820_0	530564.Psta_3804	2.152e-179	578.0	COG2866@1|root,COG2866@2|Bacteria,2J1Z2@203682|Planctomycetes	203682|Planctomycetes	M	PFAM peptidase M14 carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HSJS3_k127_8710613_2	682795.AciX8_0772	0.0008765	51.0	COG0793@1|root,COG3577@1|root,COG0793@2|Bacteria,COG3577@2|Bacteria,3Y8S0@57723|Acidobacteria	57723|Acidobacteria	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
HSJS3_k127_8710613_0	1250005.PHEL85_2215	2.637e-10	63.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia,3VWUA@52959|Polaribacter	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HSJS3_k127_8721948_0	383372.Rcas_4102	1.377e-196	625.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HSJS3_k127_8721948_9	515635.Dtur_0877	1.356e-08	67.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
HSJS3_k127_8721948_2	1408423.JHYA01000012_gene1492	4.423e-156	516.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H2FJ@909932|Negativicutes	909932|Negativicutes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HSJS3_k127_8721948_3	1191523.MROS_0061	1.354e-83	287.0	COG0506@1|root,COG0506@2|Bacteria	2|Bacteria	E	proline dehydrogenase activity	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HSJS3_k127_8721948_7	1267535.KB906767_gene3822	5.218e-13	83.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria	57723|Acidobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_8
HSJS3_k127_8721948_8	290397.Adeh_0060	9.582e-09	61.0	COG1826@1|root,COG1826@2|Bacteria,1PJQP@1224|Proteobacteria,4358S@68525|delta/epsilon subdivisions,2WZJX@28221|Deltaproteobacteria,2Z2A9@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HSJS3_k127_8721948_5	246194.CHY_0863	9.027e-32	134.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,24KCD@186801|Clostridia,42GQG@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HSJS3_k127_8721948_4	1156937.MFUM_1020071	1.544e-46	180.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia,37GAR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS3_k127_8721948_6	1408304.JAHA01000005_gene875	2.258e-26	110.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,4BZTJ@830|Butyrivibrio	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HSJS3_k127_8721948_1	485915.Dret_0561	2.866e-169	559.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2M83K@213115|Desulfovibrionales	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
HSJS3_k127_8727190_0	82654.Pse7367_2156	6.771e-56	212.0	COG0433@1|root,COG0433@2|Bacteria,1G7KD@1117|Cyanobacteria	1117|Cyanobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
HSJS3_k127_8727190_2	1173263.Syn7502_00887	2.201e-08	66.0	COG2380@1|root,COG2380@2|Bacteria,1GBVK@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_8727190_3	879212.DespoDRAFT_02962	1.224e-07	58.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2WQIY@28221|Deltaproteobacteria,2MK9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HSJS3_k127_8727190_1	518766.Rmar_1412	4.411e-21	101.0	COG0417@1|root,COG0417@2|Bacteria,4PEEF@976|Bacteroidetes,1FIZ9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA polymerase type-B family	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B,DNA_pol_B_exo1
HSJS3_k127_8737520_0	635013.TherJR_0010	3.616e-135	436.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25ZYC@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
HSJS3_k127_8810551_0	227086.JGI_V11_41402	2.201e-33	130.0	COG0372@1|root,KOG2617@2759|Eukaryota	2759|Eukaryota	C	citrate (Si)-synthase activity	CS	GO:0000166,GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005975,GO:0006081,GO:0006082,GO:0006084,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006195,GO:0006520,GO:0006536,GO:0006537,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009060,GO:0009062,GO:0009064,GO:0009084,GO:0009109,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009403,GO:0009404,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0014823,GO:0015980,GO:0016042,GO:0016053,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017001,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019637,GO:0019679,GO:0019693,GO:0019748,GO:0019752,GO:0030312,GO:0030554,GO:0031974,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0035639,GO:0036094,GO:0036440,GO:0042221,GO:0042579,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043385,GO:0043386,GO:0043436,GO:0043603,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044262,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044550,GO:0045333,GO:0045460,GO:0045461,GO:0046356,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046487,GO:0046686,GO:0046700,GO:0046872,GO:0046912,GO:0046914,GO:0050440,GO:0050896,GO:0051186,GO:0051187,GO:0055086,GO:0055114,GO:0070013,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901376,GO:1901378,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HSJS3_k127_8892651_0	324602.Caur_0573	1.098e-172	554.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi,376SB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HSJS3_k127_8899740_1	1384484.AEQU_0785	3.252e-22	98.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4CV5T@84998|Coriobacteriia	84998|Coriobacteriia	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HSJS3_k127_8899740_0	227941.CCA_00854	1.162e-22	102.0	COG0799@1|root,COG0799@2|Bacteria	2|Bacteria	S	negative regulation of ribosome biogenesis	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RsfS
HSJS3_k127_8899740_2	1304875.JAFZ01000001_gene1895	0.0007587	49.0	COG1316@1|root,COG1316@2|Bacteria,3TA77@508458|Synergistetes	508458|Synergistetes	K	TIGRFAM cell envelope-related function transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
HSJS3_k127_9085003_1	1235790.C805_01828	9.454e-80	274.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,25VRI@186806|Eubacteriaceae	186801|Clostridia	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HSJS3_k127_9085003_3	6669.EFX86461	5.363e-54	201.0	COG1446@1|root,KOG1592@2759|Eukaryota,38JIS@33154|Opisthokonta,3BB1E@33208|Metazoa,3CRC6@33213|Bilateria,41XIG@6656|Arthropoda	33208|Metazoa	E	hydrolase activity	ASRGL1	GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006528,GO:0006530,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008798,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0019439,GO:0019538,GO:0019752,GO:0032787,GO:0033345,GO:0034641,GO:0042737,GO:0043170,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0070011,GO:0071704,GO:0072329,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
HSJS3_k127_9085003_4	1209989.TepiRe1_0069	6.166e-21	107.0	2DB83@1|root,2Z7Q0@2|Bacteria,1TQP1@1239|Firmicutes,249DW@186801|Clostridia,42GCH@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF4127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4127
HSJS3_k127_9085003_2	1227352.C173_16536	1.006e-72	261.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,4HBWH@91061|Bacilli,26SAR@186822|Paenibacillaceae	91061|Bacilli	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HSJS3_k127_9085003_0	500633.CLOHIR_00230	2.274e-95	326.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25QZG@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS3_k127_9233163_2	713587.THITH_06200	0.0009338	49.0	COG1075@1|root,COG1075@2|Bacteria,1NAEF@1224|Proteobacteria,1RZCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	plaB	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9233163_1	525904.Tter_0097	2.635e-51	189.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HSJS3_k127_9233163_0	96561.Dole_2292	1.633e-62	223.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria,2MHXR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
HSJS3_k127_925777_0	1121374.KB891576_gene602	3.856e-08	59.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
HSJS3_k127_925777_1	1122176.KB903539_gene1336	2.517e-06	60.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IQVH@117747|Sphingobacteriia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
HSJS3_k127_9332384_3	886293.Sinac_0803	2.829e-05	53.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
HSJS3_k127_9332384_1	439235.Dalk_2377	1.007e-60	218.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2WN0R@28221|Deltaproteobacteria,2MJ9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
HSJS3_k127_9332384_2	716544.wcw_0294	7.192e-29	131.0	28N6X@1|root,2ZBBQ@2|Bacteria,2JFR2@204428|Chlamydiae	204428|Chlamydiae	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HSJS3_k127_9332384_0	926550.CLDAP_17900	7.025e-88	310.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HSJS3_k127_9389948_0	457570.Nther_2188	3.644e-109	382.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
HSJS3_k127_9389948_3	234267.Acid_7896	1.561e-08	65.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
HSJS3_k127_9389948_2	1250005.PHEL85_0621	4.586e-10	69.0	arCOG02770@1|root,33PR0@2|Bacteria,4P237@976|Bacteroidetes,1I7R8@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HSJS3_k127_9389948_1	936572.HMPREF1148_0207	1.393e-32	139.0	COG1560@1|root,COG1560@2|Bacteria,1TT7A@1239|Firmicutes,4H33V@909932|Negativicutes	909932|Negativicutes	M	Lipid A biosynthesis	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HSJS3_k127_9390687_0	379066.GAU_3114	2.349e-59	216.0	COG3016@1|root,COG3016@2|Bacteria,1ZUD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
HSJS3_k127_9390687_2	292459.STH1152	9.808e-10	67.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24NF2@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_9390687_1	67257.JODR01000018_gene4235	2.984e-15	83.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_9399757_0	644282.Deba_2196	4.648e-15	83.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HSJS3_k127_9403257_1	1278073.MYSTI_01391	7.326e-67	235.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42T87@68525|delta/epsilon subdivisions,2WP52@28221|Deltaproteobacteria,2YURQ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HSJS3_k127_9403257_3	227882.SAV_4614	0.0001792	48.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
HSJS3_k127_9403257_2	479434.Sthe_2983	2.131e-08	61.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,27Y1J@189775|Thermomicrobia	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,HMA,Hydrolase
HSJS3_k127_9403257_0	1121472.AQWN01000008_gene1868	1.102e-117	392.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,260V7@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HSJS3_k127_9414911_0	589865.DaAHT2_0644	1.519e-67	239.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MJDX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HSJS3_k127_9414911_1	1121422.AUMW01000001_gene2527	1.3e-13	77.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,26201@186807|Peptococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HSJS3_k127_9415082_2	748671.LCRIS_00818	2.581e-13	77.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae	91061|Bacilli	M	Involved in formation and maintenance of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HSJS3_k127_9415082_0	1523503.JPMY01000009_gene631	5.828e-42	166.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675	RsgA_GTPase
HSJS3_k127_9415082_3	1121091.AUMP01000002_gene2122	7.548e-06	57.0	COG1714@1|root,COG1714@2|Bacteria,1VATS@1239|Firmicutes,4HKJ3@91061|Bacilli	91061|Bacilli	S	membrane protein domain	yteJ	-	-	-	-	-	-	-	-	-	-	-	RDD
HSJS3_k127_9415082_1	1121289.JHVL01000001_gene1994	4.81e-36	150.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,36G1R@31979|Clostridiaceae	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HSJS3_k127_9421011_0	443218.AS9A_2937	3.533e-43	162.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,235FM@1762|Mycobacteriaceae	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
HSJS3_k127_9421011_1	710111.FraQA3DRAFT_3360	9.987e-36	144.0	COG1309@1|root,COG1309@2|Bacteria,2GJBV@201174|Actinobacteria,4EWF0@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
HSJS3_k127_9421011_3	665959.HMPREF1013_02959	1.384e-10	66.0	COG0590@1|root,COG0590@2|Bacteria,1VBAQ@1239|Firmicutes,4HKP3@91061|Bacilli,1ZHBX@1386|Bacillus	91061|Bacilli	FJ	tRNA wobble adenosine to inosine editing	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9421011_2	1192034.CAP_8821	6.325e-22	96.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HSJS3_k127_9475396_0	1158318.ATXC01000001_gene229	3.961e-133	436.0	COG0550@1|root,COG0550@2|Bacteria,2G3R3@200783|Aquificae	200783|Aquificae	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
HSJS3_k127_9475396_1	1415754.JQMK01000013_gene602	6.34e-74	262.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,465H4@72275|Alteromonadaceae	1236|Gammaproteobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HSJS3_k127_9478261_2	1125863.JAFN01000001_gene2277	3.49e-05	55.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	-
HSJS3_k127_9478261_0	1117647.M5M_01975	1.372e-13	77.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,1S70H@1236|Gammaproteobacteria,1J6ZV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Invasion gene expression up-regulator, SirB	-	-	-	-	-	-	-	-	-	-	-	-	SirB
HSJS3_k127_9478261_1	211165.AJLN01000116_gene3142	7.138e-07	53.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
HSJS3_k127_948813_1	379066.GAU_1531	1.232e-39	159.0	COG0324@1|root,COG0324@2|Bacteria,1ZTBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HSJS3_k127_948813_0	489825.LYNGBM3L_58480	2.957e-147	478.0	COG1252@1|root,COG1252@2|Bacteria,1G20T@1117|Cyanobacteria,1H80B@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase, FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HSJS3_k127_948813_3	1118054.CAGW01000063_gene2147	9.315e-06	57.0	COG0103@1|root,COG1520@1|root,COG0103@2|Bacteria,COG1520@2|Bacteria,1U1N3@1239|Firmicutes,4IB4I@91061|Bacilli,273PI@186822|Paenibacillaceae	91061|Bacilli	J	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_948813_2	1122194.AUHU01000014_gene1158	9.071e-35	144.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,467T2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
HSJS3_k127_9512479_0	573064.Mefer_0200	2.404e-20	106.0	COG1614@1|root,arCOG04360@2157|Archaea,2XU0D@28890|Euryarchaeota,23Q7P@183939|Methanococci	183939|Methanococci	C	Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex)	cdhC	-	1.2.7.4	ko:K00192,ko:K00193	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00357,M00422	R07157,R09096,R10219	RC00004,RC00113,RC02800,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
HSJS3_k127_9534007_4	1033736.CAHK01000003_gene2751	8.791e-05	55.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4F8FF@85019|Brevibacteriaceae	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
HSJS3_k127_9534007_3	1033743.CAES01000078_gene3811	7.421e-06	57.0	2BZCW@1|root,32R4U@2|Bacteria,1VK3Y@1239|Firmicutes,4HR17@91061|Bacilli,26YWH@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
HSJS3_k127_9534007_5	1242864.D187_004403	0.0001905	53.0	2A5Z5@1|root,30URA@2|Bacteria,1PVG3@1224|Proteobacteria,434XN@68525|delta/epsilon subdivisions,2WZ8E@28221|Deltaproteobacteria,2Z1JW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9534007_1	1256908.HMPREF0373_01696	2.573e-36	151.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,25V2Z@186806|Eubacteriaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HSJS3_k127_9534007_0	319795.Dgeo_0757	2.071e-92	317.0	COG1459@1|root,COG1459@2|Bacteria,1WIU3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	PFAM Bacterial type II secretion system protein F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HSJS3_k127_9534007_2	515635.Dtur_0877	4.276e-12	71.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
HSJS3_k127_9537981_0	1121430.JMLG01000002_gene1155	7.231e-204	659.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,260C9@186807|Peptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HSJS3_k127_9537981_2	1303518.CCALI_00247	1.512e-05	56.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	ydzE	-	-	-	-	-	-	-	-	-	-	-	EamA
HSJS3_k127_9537981_1	1382359.JIAL01000001_gene1535	3.574e-71	258.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HSJS3_k127_9537981_3	866895.HBHAL_1085	0.0001189	52.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3NDE0@45667|Halobacillus	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HSJS3_k127_9557069_1	1131269.AQVV01000004_gene636	8.072e-68	241.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
HSJS3_k127_9557069_0	391625.PPSIR1_39300	2.208e-73	257.0	COG3361@1|root,COG3361@2|Bacteria,1Q2C9@1224|Proteobacteria,437YP@68525|delta/epsilon subdivisions,2X38K@28221|Deltaproteobacteria,2YUU6@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
HSJS3_k127_9557468_6	713586.KB900536_gene829	7.104e-50	185.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,1T2UV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Thij pfpi	inhA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
HSJS3_k127_9557468_1	1288963.ADIS_1532	7.247e-148	487.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,47N8E@768503|Cytophagia	976|Bacteroidetes	U	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
HSJS3_k127_9557468_4	272952.HpaP806918	6.515e-84	289.0	COG0042@1|root,KOG2335@2759|Eukaryota,3QEGX@4776|Peronosporales	4776|Peronosporales	J	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	-	-	-	-	-	-	-	-	-	-	-	-	Dus
HSJS3_k127_9557468_3	1273538.G159_19780	1.14e-101	338.0	COG2321@1|root,COG2321@2|Bacteria,1TQKF@1239|Firmicutes,4HB7I@91061|Bacilli,26E8G@186818|Planococcaceae	91061|Bacilli	S	Putative neutral zinc metallopeptidase	XK27_03670	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
HSJS3_k127_9557468_7	1033806.HTIA_2513	8.548e-23	115.0	arCOG02420@1|root,arCOG03991@1|root,arCOG02420@2157|Archaea,arCOG03991@2157|Archaea,2Y822@28890|Euryarchaeota	28890|Euryarchaeota	S	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Pilin_N
HSJS3_k127_9557468_2	1121403.AUCV01000040_gene4280	8.254e-125	411.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42MUA@68525|delta/epsilon subdivisions,2WJWH@28221|Deltaproteobacteria,2MJ2G@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HSJS3_k127_9557468_5	1304885.AUEY01000014_gene3322	5.567e-77	273.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2MKXA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
HSJS3_k127_9557468_0	880072.Desac_2067	2.061e-247	777.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2MR4W@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Elongation factor Tu domain 2	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
HSJS3_k127_9562787_1	121225.PHUM011730-PA	2.903e-22	104.0	KOG3678@1|root,KOG3678@2759|Eukaryota,38FZM@33154|Opisthokonta,3BBRG@33208|Metazoa,3D1T5@33213|Bilateria,41TPQ@6656|Arthropoda,3SGZ4@50557|Insecta,3E7DS@33342|Paraneoptera	33208|Metazoa	W	Sterile alpha motif.	SARM1	GO:0002682,GO:0002683,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005856,GO:0005874,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0009611,GO:0009743,GO:0009746,GO:0009749,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010769,GO:0010941,GO:0010975,GO:0015630,GO:0016020,GO:0019867,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030424,GO:0030425,GO:0031090,GO:0031312,GO:0031315,GO:0031344,GO:0031347,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0034121,GO:0034122,GO:0034127,GO:0034128,GO:0034284,GO:0036477,GO:0042221,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043067,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045088,GO:0045202,GO:0045595,GO:0045664,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048678,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051716,GO:0051960,GO:0060284,GO:0065007,GO:0080134,GO:0097447,GO:0097458,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	SAM_2,TIR_2
HSJS3_k127_9562787_0	649747.HMPREF0083_06251	5.535e-106	359.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HT98@91061|Bacilli,277FI@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HSJS3_k127_9562787_3	1297865.APJD01000031_gene1583	3.438e-05	51.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JTAD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Heavy-metal-associated domain	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HSJS3_k127_9562787_2	1828.JOKB01000009_gene5358	6.003e-14	79.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4FVYM@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HSJS3_k127_9572670_1	1121104.AQXH01000001_gene1249	2.296e-135	445.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	hndC	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HSJS3_k127_9572670_9	1313172.YM304_04100	7.182e-22	104.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CN1U@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HSJS3_k127_9572670_0	237368.SCABRO_02007	6.196e-136	444.0	COG0649@1|root,COG0649@2|Bacteria,2IY7J@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
HSJS3_k127_9572670_7	944481.JAFP01000001_gene1528	3.308e-38	149.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2WQB1@28221|Deltaproteobacteria,2M6PV@213113|Desulfurellales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
HSJS3_k127_9572670_3	1379698.RBG1_1C00001G1051	2.563e-62	220.0	COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HSJS3_k127_9572670_10	314225.ELI_06695	9.703e-17	86.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,2K4KM@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HSJS3_k127_9572670_6	351607.Acel_1009	1.932e-43	175.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4ES9A@85013|Frankiales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
HSJS3_k127_9572670_2	1120985.AUMI01000015_gene1501	1.971e-87	305.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4H30K@909932|Negativicutes	909932|Negativicutes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_9572670_5	1410628.JNKS01000030_gene2904	7.86e-46	179.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,27IAW@186928|unclassified Lachnospiraceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HSJS3_k127_9572670_4	574087.Acear_0742	1.213e-59	228.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WAD2@53433|Halanaerobiales	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_9572670_8	537013.CLOSTMETH_03312	2.14e-24	104.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WHE3@541000|Ruminococcaceae	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HSJS3_k127_9577805_9	1120792.JAFV01000001_gene2943	0.0008535	47.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,36YA4@31993|Methylocystaceae	28211|Alphaproteobacteria	H	Dephospho-CoA kinase	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HSJS3_k127_9577805_4	66692.ABC0644	2.93e-31	132.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4HGXQ@91061|Bacilli,1ZFQT@1386|Bacillus	91061|Bacilli	G	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	celCD	-	2.7.1.196,2.7.1.205,3.5.1.105	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	YdjC
HSJS3_k127_9577805_6	324602.Caur_3597	1.985e-25	124.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,37570@32061|Chloroflexia	32061|Chloroflexia	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
HSJS3_k127_9577805_7	1123326.JFBL01000002_gene1670	2.387e-21	107.0	COG1721@1|root,COG1721@2|Bacteria,1RA3X@1224|Proteobacteria,42UN9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HSJS3_k127_9577805_0	1174504.AJTN02000003_gene2110	1.966e-112	372.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZDJ1@1386|Bacillus	91061|Bacilli	S	COG0714 MoxR-like ATPases	yeaC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HSJS3_k127_9577805_3	240015.ACP_1626	1.968e-40	158.0	COG1853@1|root,COG1853@2|Bacteria,3Y51K@57723|Acidobacteria,2JMFE@204432|Acidobacteriia	204432|Acidobacteriia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HSJS3_k127_9577805_1	479434.Sthe_0408	1.756e-86	298.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,27XWX@189775|Thermomicrobia	189775|Thermomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HSJS3_k127_9577805_5	404589.Anae109_2535	2.466e-26	114.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HSJS3_k127_9577805_2	269797.Mbar_A1866	1.677e-45	175.0	COG1712@1|root,arCOG00254@2157|Archaea,2XUNA@28890|Euryarchaeota,2NBJI@224756|Methanomicrobia	224756|Methanomicrobia	F	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
HSJS3_k127_9577805_8	584708.Apau_0949	1.745e-14	81.0	29A4E@1|root,2ZX5H@2|Bacteria,3TB5P@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9581187_2	1380390.JIAT01000017_gene5273	4.961e-12	69.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CPI6@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HSJS3_k127_9581187_1	574376.BAMA_14165	2.461e-65	233.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus	91061|Bacilli	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22430	Pantoate_transf
HSJS3_k127_9581187_0	349102.Rsph17025_2495	1.825e-77	269.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,1FB8J@1060|Rhodobacter	28211|Alphaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HSJS3_k127_9610339_2	671143.DAMO_2943	1.078e-65	229.0	COG0451@1|root,COG0451@2|Bacteria,2NPSM@2323|unclassified Bacteria	2|Bacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO0058,iYL1228.KPN_03963	Epimerase
HSJS3_k127_9610339_5	362976.HQ_1466A	1.713e-18	90.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HSJS3_k127_9610339_6	368407.Memar_1137	2.621e-18	99.0	COG1305@1|root,arCOG02167@2157|Archaea	2157|Archaea	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HSJS3_k127_9610339_1	391623.TERMP_00505	6.264e-68	249.0	COG1457@1|root,arCOG03447@2157|Archaea,2Y0SR@28890|Euryarchaeota,2436W@183968|Thermococci	183968|Thermococci	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
HSJS3_k127_9610339_0	1111479.AXAR01000023_gene2903	1.247e-234	743.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,2788E@186823|Alicyclobacillaceae	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
HSJS3_k127_9610339_4	1288484.APCS01000110_gene1159	3.746e-23	106.0	COG1544@1|root,COG1544@2|Bacteria,1WJUY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HSJS3_k127_9610339_7	1173025.GEI7407_0339	2.276e-06	59.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
HSJS3_k127_9610339_3	1304875.JAFZ01000001_gene1319	1.091e-64	231.0	COG1212@1|root,COG1212@2|Bacteria,3TA3G@508458|Synergistetes	508458|Synergistetes	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
HSJS3_k127_9628733_2	500635.MITSMUL_05214	4.154e-14	82.0	COG1566@1|root,COG1566@2|Bacteria,1TRB8@1239|Firmicutes,4H2VS@909932|Negativicutes	909932|Negativicutes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HSJS3_k127_9628733_1	349521.HCH_05430	2.707e-15	79.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1XMVY@135619|Oceanospirillales	135619|Oceanospirillales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HSJS3_k127_9628733_4	56107.Cylst_4306	4.086e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1HIQE@1161|Nostocales	1117|Cyanobacteria	K	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
HSJS3_k127_9628733_3	525904.Tter_1208	7.412e-14	83.0	COG0400@1|root,COG0400@2|Bacteria,2NRU7@2323|unclassified Bacteria	2|Bacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
HSJS3_k127_9628733_0	1121930.AQXG01000008_gene116	7.11e-51	200.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
HSJS3_k127_9655022_0	1353528.DT23_05040	7.289e-20	98.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,2XN3R@285107|Thioclava	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HSJS3_k127_9655022_1	926550.CLDAP_22820	6.607e-06	56.0	COG0845@1|root,COG0845@2|Bacteria,2G8HH@200795|Chloroflexi	200795|Chloroflexi	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
HSJS3_k127_9658906_0	1907.SGLAU_08740	1.185e-115	382.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HSJS3_k127_9658906_3	1120936.KB907208_gene786	1.114e-41	165.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4EH37@85012|Streptosporangiales	201174|Actinobacteria	M	RmlD substrate binding domain	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HSJS3_k127_9658906_5	69042.WH5701_15896	2.908e-07	63.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria,1GZKT@1129|Synechococcus	1117|Cyanobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	comA	-	-	-	-	-	-	-	-	-	-	-	HHH_3,PLDc_2
HSJS3_k127_9658906_6	383372.Rcas_0293	2.112e-05	57.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi,3757B@32061|Chloroflexia	32061|Chloroflexia	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
HSJS3_k127_9658906_4	1385510.N781_09540	3.746e-12	79.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1UXD9@1239|Firmicutes,4I2J1@91061|Bacilli,2YBSI@289201|Pontibacillus	91061|Bacilli	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9658906_1	1121920.AUAU01000027_gene1499	6.839e-79	268.0	COG1335@1|root,COG1335@2|Bacteria,3Y5W2@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HSJS3_k127_9658906_2	1120954.ATXE01000002_gene687	3.526e-51	191.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DNT7@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HSJS3_k127_9658906_7	1463881.KL591008_gene1823	0.0007807	45.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HSJS3_k127_9677989_0	1118054.CAGW01000049_gene1680	5.759e-47	174.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,274ZQ@186822|Paenibacillaceae	91061|Bacilli	V	ABC-2 type transporter	ybhR	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HSJS3_k127_9677989_1	608506.COB47_0163	8.735e-47	182.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,42F0X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HSJS3_k127_9677989_3	1121413.JMKT01000009_gene2170	1.154e-24	106.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HSJS3_k127_9677989_2	685778.AORL01000010_gene2890	7.175e-28	126.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,2U06S@28211|Alphaproteobacteria,2JZZD@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
HSJS3_k127_9692797_0	1123508.JH636443_gene4721	1.577e-44	170.0	COG2890@1|root,COG2890@2|Bacteria,2IYX6@203682|Planctomycetes	203682|Planctomycetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
HSJS3_k127_9692797_3	1449080.JQMV01000003_gene699	2.814e-14	80.0	COG0009@1|root,COG0009@2|Bacteria,1WJN4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Sua5 YciO YrdC YwlC family protein	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HSJS3_k127_9692797_5	1116232.AHBF01000125_gene9441	5.626e-06	61.0	COG4733@1|root,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
HSJS3_k127_9692797_2	456442.Mboo_0818	8.089e-29	136.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
HSJS3_k127_9692797_4	1449063.JMLS01000002_gene1370	7.286e-14	87.0	COG2247@1|root,COG2755@1|root,COG3250@1|root,COG5434@1|root,COG2247@2|Bacteria,COG2755@2|Bacteria,COG3250@2|Bacteria,COG5434@2|Bacteria,1UWBV@1239|Firmicutes,4I2E0@91061|Bacilli,26W7A@186822|Paenibacillaceae	91061|Bacilli	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C
HSJS3_k127_9692797_1	313596.RB2501_13489	5.36e-35	154.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
HSJS3_k127_9698126_2	1453505.JASY01000003_gene2225	3.376e-10	70.0	COG4932@1|root,COG4932@2|Bacteria,4NT1H@976|Bacteroidetes,1I663@117743|Flavobacteriia,2NV9S@237|Flavobacterium	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9698126_0	243274.THEMA_02070	3.279e-68	236.0	COG5405@1|root,COG5405@2|Bacteria,2GCRK@200918|Thermotogae	200918|Thermotogae	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
HSJS3_k127_9698126_1	927658.AJUM01000037_gene1982	6.305e-19	95.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,2FNNF@200643|Bacteroidia,3XJ64@558415|Marinilabiliaceae	976|Bacteroidetes	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HSJS3_k127_9730930_0	1449126.JQKL01000061_gene1910	3.311e-220	701.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,2682S@186813|unclassified Clostridiales	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HSJS3_k127_9730930_2	882.DVU_0499	3.7e-38	147.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2WQ0Z@28221|Deltaproteobacteria,2MBJY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
HSJS3_k127_9730930_1	1047013.AQSP01000125_gene2629	1.035e-52	205.0	COG4365@1|root,COG4365@2|Bacteria,2NP8Q@2323|unclassified Bacteria	2|Bacteria	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HSJS3_k127_9732752_0	330214.NIDE2553	6.601e-64	231.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
HSJS3_k127_9755396_0	398579.Spea_0316	1.327e-26	118.0	COG1075@1|root,COG1075@2|Bacteria,1NAEF@1224|Proteobacteria,1RZCX@1236|Gammaproteobacteria,2QB8G@267890|Shewanellaceae	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	plaB	-	-	-	-	-	-	-	-	-	-	-	-
HSJS3_k127_9757096_7	1448860.BBJO01000014_gene1290	3.95e-05	46.0	COG1250@1|root,arCOG00250@2157|Archaea,2XT9S@28890|Euryarchaeota,23TDY@183963|Halobacteria	183963|Halobacteria	I	3-hydroxyacyl-CoA dehydrogenase	hbd3	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HSJS3_k127_9757096_6	1179226.AJXO01000003_gene1667	2.838e-05	53.0	COG2010@1|root,COG2010@2|Bacteria,1VBJT@1239|Firmicutes,4HKX4@91061|Bacilli,4GZRQ@90964|Staphylococcaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	cccA	-	-	ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
HSJS3_k127_9757096_3	720554.Clocl_1565	2.264e-24	120.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24A1W@186801|Clostridia	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_19
HSJS3_k127_9757096_2	243090.RB8026	2.079e-34	144.0	COG1262@1|root,COG1262@2|Bacteria,2J355@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HSJS3_k127_9757096_4	485913.Krac_4070	1.732e-15	83.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HSJS3_k127_9757096_0	360911.EAT1b_2229	2.637e-179	597.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,3WEP9@539002|Bacillales incertae sedis	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HSJS3_k127_9757096_1	373994.Riv7116_0552	8.594e-154	499.0	COG0034@1|root,COG0034@2|Bacteria,1G1C9@1117|Cyanobacteria,1HJQK@1161|Nostocales	1117|Cyanobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HSJS3_k127_9757096_5	1173022.Cri9333_1649	1.731e-10	71.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8
HSJS3_k127_9802201_2	1128421.JAGA01000003_gene3247	8.403e-63	239.0	COG2304@1|root,COG2304@2|Bacteria,2NQHG@2323|unclassified Bacteria	2|Bacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
HSJS3_k127_9802201_4	1329516.JPST01000038_gene2745	6.956e-43	170.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HBIW@91061|Bacilli,27BFM@186824|Thermoactinomycetaceae	91061|Bacilli	K	Sigma-70 region 3	sigB	GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043620,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HSJS3_k127_9802201_5	1347087.CBYO010000004_gene455	4.89e-09	63.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli	91061|Bacilli	T	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
HSJS3_k127_9802201_1	1118054.CAGW01000024_gene455	2.683e-73	258.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HDBB@91061|Bacilli,274T8@186822|Paenibacillaceae	91061|Bacilli	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HSJS3_k127_9802201_0	1461580.CCAS010000019_gene2200	2.035e-92	315.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,1ZBXY@1386|Bacillus	91061|Bacilli	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HSJS3_k127_9802201_3	891968.Anamo_2096	5.578e-44	167.0	COG4166@1|root,COG4166@2|Bacteria,3TA34@508458|Synergistetes	508458|Synergistetes	E	family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
HSJS3_k127_984418_1	314230.DSM3645_25522	4.198e-19	89.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,2IXEW@203682|Planctomycetes	203682|Planctomycetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
HSJS3_k127_984418_0	313606.M23134_03791	3.113e-81	280.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,47NU5@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
HSJS3_k127_984418_2	83406.HDN1F_13540	1.984e-07	57.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1J670@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
HSJS3_k127_9854416_0	478741.JAFS01000002_gene421	3.624e-42	163.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,37GTF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HSJS3_k127_9854416_1	867903.ThesuDRAFT_00332	3.333e-37	160.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WCKM@538999|Clostridiales incertae sedis	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HSJS3_k127_9924123_2	1382356.JQMP01000004_gene476	2.417e-09	65.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,27YAY@189775|Thermomicrobia	189775|Thermomicrobia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HSJS3_k127_9924123_0	383372.Rcas_1103	8.757e-66	235.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,374SY@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HSJS3_k127_9924123_1	1184267.A11Q_2030	5.214e-50	198.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2MSU9@213481|Bdellovibrionales,2WK0W@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
## 1361 queries scanned
## Total time (seconds): 157.2822368144989
## Rate: 8.65 q/s